ID GB_ACC SPOT_ID Species Scientific Name Annotation Date Sequence Type Sequence Source Target Description Representative Public ID Gene Title Gene Symbol ENTREZ_GENE_ID RefSeq Transcript ID Gene Ontology Biological Process Gene Ontology Cellular Component Gene Ontology Molecular Function 1007_s_at U48705 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database "U48705 /FEATURE=mRNA /DEFINITION=HSU48705 Human receptor tyrosine kinase DDR gene, complete cds" U48705 discoidin domain receptor tyrosine kinase 1 /// microRNA 4640 DDR1 /// MIR4640 780 /// 100616237 NM_001202521 /// NM_001202522 /// NM_001202523 /// NM_001954 /// NM_013993 /// NM_013994 /// NR_039783 /// XM_005249385 /// XM_005249386 /// XM_005249387 /// XM_005249389 /// XM_005272873 /// XM_005272874 /// XM_005272875 /// XM_005272877 /// XM_005275027 /// XM_005275028 /// XM_005275030 /// XM_005275031 /// XM_005275162 /// XM_005275163 /// XM_005275164 /// XM_005275166 /// XM_005275457 /// XM_005275458 /// XM_005275459 /// XM_005275461 /// XM_006715185 /// XM_006715186 /// XM_006715187 /// XM_006715188 /// XM_006715189 /// XM_006715190 /// XM_006725501 /// XM_006725502 /// XM_006725503 /// XM_006725504 /// XM_006725505 /// XM_006725506 /// XM_006725714 /// XM_006725715 /// XM_006725716 /// XM_006725717 /// XM_006725718 /// XM_006725719 /// XM_006725720 /// XM_006725721 /// XM_006725722 /// XM_006725827 /// XM_006725828 /// XM_006725829 /// XM_006725830 /// XM_006725831 /// XM_006725832 /// XM_006726017 /// XM_006726018 /// XM_006726019 /// XM_006726020 /// XM_006726021 /// XM_006726022 /// XR_427836 /// XR_430858 /// XR_430938 /// XR_430974 /// XR_431015 "0001558 // regulation of cell growth // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from direct assay /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0061302 // smooth muscle cell-matrix adhesion // inferred from mutant phenotype" 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0005518 // collagen binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038062 // protein tyrosine kinase collagen receptor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 1053_at M87338 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "M87338 /FEATURE= /DEFINITION=HUMA1SBU Human replication factor C, 40-kDa subunit (A1) mRNA, complete cds" M87338 "replication factor C (activator 1) 2, 40kDa" RFC2 5982 NM_001278791 /// NM_001278792 /// NM_001278793 /// NM_002914 /// NM_181471 /// XM_006716080 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 117_at X51757 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database X51757 /FEATURE=cds /DEFINITION=HSP70B Human heat-shock protein HSP70B' gene X51757 heat shock 70kDa protein 6 (HSP70B') HSPA6 3310 NM_002155 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0070370 // cellular heat acclimation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay" 121_at X69699 Homo sapiens 6-Oct-14 Exemplar sequence GenBank X69699 /FEATURE= /DEFINITION=HSPAX8A H.sapiens Pax8 mRNA X69699 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 "0001655 // urogenital system development // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from expression pattern /// 0001823 // mesonephros development // inferred from sequence or structural similarity /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from expression pattern /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0030878 // thyroid gland development // inferred from mutant phenotype /// 0038194 // thyroid-stimulating hormone signaling pathway // traceable author statement /// 0039003 // pronephric field specification // inferred from sequence or structural similarity /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048793 // pronephros development // inferred from sequence or structural similarity /// 0071371 // cellular response to gonadotropin stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from expression pattern /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072073 // kidney epithelium development // inferred from electronic annotation /// 0072108 // positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0072164 // mesonephric tubule development // inferred from electronic annotation /// 0072207 // metanephric epithelium development // inferred from expression pattern /// 0072221 // metanephric distal convoluted tubule development // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0072305 // negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis // inferred from sequence or structural similarity /// 0072307 // regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900212 // negative regulation of mesenchymal cell apoptotic process involved in metanephros development // inferred from sequence or structural similarity /// 1900215 // negative regulation of apoptotic process involved in metanephric collecting duct development // inferred from sequence or structural similarity /// 1900218 // negative regulation of apoptotic process involved in metanephric nephron tubule development // inferred from sequence or structural similarity /// 2000594 // positive regulation of metanephric DCT cell differentiation // inferred from sequence or structural similarity /// 2000611 // positive regulation of thyroid hormone generation // inferred from mutant phenotype /// 2000612 // regulation of thyroid-stimulating hormone secretion // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 1255_g_at L36861 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database "L36861 /FEATURE=expanded_cds /DEFINITION=HUMGCAPB Homo sapiens guanylate cyclase activating protein (GCAP) gene exons 1-4, complete cds" L36861 guanylate cyclase activator 1A (retina) GUCA1A 2978 NM_000409 /// XM_006715073 "0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0031282 // regulation of guanylate cyclase activity // inferred from electronic annotation /// 0031284 // positive regulation of guanylate cyclase activity // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation" 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0097381 // photoreceptor disc membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // inferred from electronic annotation /// 0030249 // guanylate cyclase regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 1294_at L13852 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "L13852 /FEATURE= /DEFINITION=HUME1URP Homo sapiens ubiquitin-activating enzyme E1 related protein mRNA, complete cds" L13852 microRNA 5193 /// ubiquitin-like modifier activating enzyme 7 MIR5193 /// UBA7 7318 /// 100847079 NM_003335 /// NR_049825 /// XM_005265430 /// XM_006713321 0006464 // cellular protein modification process // inferred from direct assay /// 0016567 // protein ubiquitination // not recorded /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019941 // modification-dependent protein catabolic process // not recorded /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // not recorded /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019782 // ISG15 activating enzyme activity // inferred from direct assay 1316_at X55005 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database "X55005 /FEATURE=mRNA /DEFINITION=HSCERBAR Homo sapiens mRNA for thyroid hormone receptor alpha 1 THRA1, (c-erbA-1 gene)" X55005 "thyroid hormone receptor, alpha" THRA 7067 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_199334 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 1320_at X79510 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database X79510 /FEATURE=cds /DEFINITION=HSPTPD1 H.sapiens mRNA for protein-tyrosine-phosphatase D1 X79510 "protein tyrosine phosphatase, non-receptor type 21" PTPN21 11099 NM_007039 /// XM_005267287 /// XM_006720011 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 1405_i_at M21121 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "M21121 /FEATURE= /DEFINITION=HUMTCSM Human T cell-specific protein (RANTES) mRNA, complete cds" M21121 chemokine (C-C motif) ligand 5 CCL5 6352 NM_001278736 /// NM_002985 0000165 // MAPK cascade // inferred from mutant phenotype /// 0002407 // dendritic cell chemotaxis // traceable author statement /// 0002548 // monocyte chemotaxis // inferred by curator /// 0002676 // regulation of chronic inflammatory response // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0006887 // exocytosis // inferred from direct assay /// 0006935 // chemotaxis // non-traceable author statement /// 0006954 // inflammatory response // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009615 // response to virus // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0010535 // positive regulation of activation of JAK2 kinase activity // traceable author statement /// 0010759 // positive regulation of macrophage chemotaxis // inferred from direct assay /// 0010820 // positive regulation of T cell chemotaxis // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031328 // positive regulation of cellular biosynthetic process // inferred from direct assay /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034112 // positive regulation of homotypic cell-cell adhesion // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042119 // neutrophil activation // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043623 // cellular protein complex assembly // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from expression pattern /// 0045070 // positive regulation of viral genome replication // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045089 // positive regulation of innate immune response // traceable author statement /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0045948 // positive regulation of translational initiation // non-traceable author statement /// 0046427 // positive regulation of JAK-STAT cascade // traceable author statement /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0048246 // macrophage chemotaxis // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050863 // regulation of T cell activation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070098 // chemokine-mediated signaling pathway // traceable author statement /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from direct assay /// 0070233 // negative regulation of T cell apoptotic process // inferred from direct assay /// 0070234 // positive regulation of T cell apoptotic process // inferred from direct assay /// 0071346 // cellular response to interferon-gamma // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 2000110 // negative regulation of macrophage apoptotic process // inferred from electronic annotation /// 2000406 // positive regulation of T cell migration // inferred from direct assay /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // non-traceable author statement /// 0016004 // phospholipase activator activity // inferred from direct assay /// 0030298 // receptor signaling protein tyrosine kinase activator activity // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from direct assay /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction /// 0031726 // CCR1 chemokine receptor binding // traceable author statement /// 0031729 // CCR4 chemokine receptor binding // traceable author statement /// 0031730 // CCR5 chemokine receptor binding // inferred from physical interaction /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042379 // chemokine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0046817 // chemokine receptor antagonist activity // inferred from direct assay 1431_at J02843 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database "J02843 /FEATURE=cds /DEFINITION=HUMCYPIIE Human cytochrome P450IIE1 (ethanol-inducible) gene, complete cds" J02843 "cytochrome P450, family 2, subfamily E, polypeptide 1" CYP2E1 1571 NM_000773 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0010193 // response to ozone // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // traceable author statement /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation" 1438_at X75208 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database X75208 /FEATURE=cds /DEFINITION=HSPTKR H.sapiens HEK2 mRNA for protein tyrosine kinase receptor X75208 EPH receptor B3 EPHB3 2049 NM_004443 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001655 // urogenital system development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007413 // axonal fasciculation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0022407 // regulation of cell-cell adhesion // inferred from direct assay /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048546 // digestive tract morphogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 1487_at L38487 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database "L38487 /FEATURE=mRNA /DEFINITION=HUMHERRA1 Human estrogen receptor-related protein (hERRa1) mRNA, 3' end, partial cds" L38487 estrogen-related receptor alpha ESRRA 2101 NM_001282450 /// NM_001282451 /// NM_004451 /// XM_006718449 /// XM_006718450 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 1494_f_at M33318 Homo sapiens 6-Oct-14 Exemplar sequence Affymetrix Proprietary Database "M33318 /FEATURE=mRNA /DEFINITION=HUMCPIIA3A Human cytochrome P450IIA3 (CYP2A3) mRNA, complete cds" M33318 "cytochrome P450, family 2, subfamily A, polypeptide 6" CYP2A6 1548 NM_000762 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0009804 // coumarin metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from mutant phenotype /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046226 // coumarin catabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation" 1598_g_at L13720 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "L13720 /FEATURE= /DEFINITION=HUMGAS Homo sapiens growth-arrest-specific protein (gas) mRNA, complete cds" L13720 growth arrest-specific 6 GAS6 2621 NM_000820 /// NM_001143945 /// NM_001143946 "0001764 // neuron migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006909 // phagocytosis // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010934 // macrophage cytokine production // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019064 // fusion of virus membrane with host plasma membrane // inferred from direct assay /// 0019079 // viral genome replication // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033159 // negative regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035754 // B cell chemotaxis // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046718 // viral entry into host cell // inferred from direct assay /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050711 // negative regulation of interleukin-1 secretion // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070168 // negative regulation of biomineral tissue development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071307 // cellular response to vitamin K // inferred from direct assay /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 0097241 // hematopoietic stem cell migration to bone marrow // inferred from direct assay /// 1900142 // negative regulation of oligodendrocyte apoptotic process // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from direct assay /// 2000533 // negative regulation of renal albumin absorption // inferred from sequence or structural similarity /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0001786 // phosphatidylserine binding // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048018 // receptor agonist activity // inferred from direct assay /// 0060090 // binding, bridging // inferred from direct assay" 160020_at Z48481 Homo sapiens 6-Oct-14 Consensus sequence GenBank Z48481 /FEATURE=cds /DEFINITION=HSMMPM1 H.sapiens mRNA for membrane-type matrix metalloproteinase 1 /NOTE=replacement of probe set 1301_s_at Z48481 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 "0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 1729_at L41690 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "L41690 /FEATURE= /DEFINITION=HUMTRADD Homo sapiens TNF receptor-1 associated protein (TRADD) mRNA, 3' end of cds" L41690 TNFRSF1A-associated via death domain TRADD 8717 NM_003789 /// NM_153425 /// XM_005256213 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation "0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from physical interaction /// 0070513 // death domain binding // inferred from physical interaction" 1773_at L00635 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "L00635 /FEATURE= /DEFINITION=HUMFPTB Human farnesyl-protein transferase beta-subunit mRNA, complete cds" L00635 "CHURC1-FNTB readthrough /// farnesyltransferase, CAAX box, beta" CHURC1-FNTB /// FNTB 2342 /// 100529261 NM_001202558 /// NM_001202559 /// NM_002028 "0007275 // multicellular organismal development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018343 // protein farnesylation // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from electronic annotation" 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005965 // protein farnesyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 177_at U38545 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "U38545 /FEATURE= /DEFINITION=HSU38545 Human ARF-activated phosphatidylcholine-specific phospholipase D1a (hPLD1) mRNA, complete cds" U38545 "phospholipase D1, phosphatidylcholine-specific" PLD1 5337 NM_001130081 /// NM_002662 /// XM_005247533 /// XM_005247534 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 179_at U38980 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "U38980 /FEATURE= /DEFINITION=U38980 Human PMS2 related (hPMSR6) mRNA, complete cds" U38980 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene DTX2P1-UPK3BP1-PMS2P11 441263 NR_023383 0006298 // mismatch repair // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0032300 // mismatch repair complex // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 1861_at U66879 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "U66879 /FEATURE= /DEFINITION=HSU66879 Human Bcl-2 binding component 6 (bbc6) mRNA, complete cds" U66879 BCL2-associated agonist of cell death BAD 572 NM_004322 /// NM_032989 0001666 // response to hypoxia // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // traceable author statement /// 0010918 // positive regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019050 // suppression by virus of host apoptotic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044342 // type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046031 // ADP metabolic process // inferred from sequence or structural similarity /// 0046034 // ATP metabolic process // inferred from sequence or structural similarity /// 0046902 // regulation of mitochondrial membrane permeability // inferred from mutant phenotype /// 0046931 // pore complex assembly // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060139 // positive regulation of apoptotic process by virus // inferred from electronic annotation /// 0060154 // cellular process regulating host cell cycle in response to virus // inferred from electronic annotation /// 0071247 // cellular response to chromate // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071316 // cellular response to nicotine // inferred from direct assay /// 0071396 // cellular response to lipid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901216 // positive regulation of neuron death // inferred from electronic annotation /// 2000078 // positive regulation of type B pancreatic cell development // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from mutant phenotype /// 0008289 // lipid binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200000_s_at NM_006445 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006445.1 /DEF=Homo sapiens U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p (PRP8), mRNA. /FEA=mRNA /GEN=PRP8 /PROD=U5 snRNP-specific protein (220 kD), ortholog ofS. cerevisiae Prp8p /DB_XREF=gi:5453983 /UG=Hs.181368 U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p /FL=gb:AB007510.1 gb:AF092565.1 gb:NM_006445.1" NM_006445 pre-mRNA processing factor 8 PRPF8 10594 NM_006445 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005682 // U5 snRNP // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from electronic annotation /// 0030623 // U5 snRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200001_at NM_001749 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001749.1 /DEF=Homo sapiens calpain 4, small subunit (30K) (CAPN4), mRNA. /FEA=mRNA /GEN=CAPN4 /PROD=calpain 4 small subunit /DB_XREF=gi:4502564 /UG=Hs.74451 calpain 4, small subunit (30K) /FL=gb:BC000592.1 gb:NM_001749.1" NM_001749 "calpain, small subunit 1" CAPNS1 826 NM_001003962 /// NM_001749 /// XM_005259295 /// XM_005259296 /// XM_005259297 0006508 // proteolysis // not recorded /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200002_at NM_007209 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007209.1 /DEF=Homo sapiens ribosomal protein L35 (RPL35), mRNA. /FEA=mRNA /GEN=RPL35 /PROD=ribosomal protein L35 /DB_XREF=gi:6005859 /UG=Hs.182825 ribosomal protein L35 /FL=gb:BC000348.1 gb:U12465.1 gb:NM_007209.1" NM_007209 ribosomal protein L35 RPL35 11224 NM_007209 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003729 // mRNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200003_s_at NM_000991 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000991.1 /DEF=Homo sapiens ribosomal protein L28 (RPL28), mRNA. /FEA=mRNA /GEN=RPL28 /PROD=ribosomal protein L28 /DB_XREF=gi:4506626 /UG=Hs.4437 ribosomal protein L28 /FL=gb:BC000072.1 gb:NM_000991.1 gb:U14969.1" NM_000991 microRNA 6805 /// ribosomal protein L28 MIR6805 /// RPL28 6158 /// 102465483 NM_000991 /// NM_001136134 /// NM_001136135 /// NM_001136136 /// NM_001136137 /// NR_106863 /// XM_005259132 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200004_at NM_001418 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001418.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2), mRNA. /FEA=mRNA /GEN=EIF4G2 /PROD=eukaryotic translation initiation factor 4gamma, 2 /DB_XREF=gi:4503538 /UG=Hs.183684 eukaryotic translation initiation factor 4 gamma, 2 /FL=gb:U73824.1 gb:U76111.1 gb:NM_001418.1" NM_001418 "eukaryotic translation initiation factor 4 gamma, 2" EIF4G2 1982 NM_001042559 /// NM_001172705 /// NM_001418 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0008219 // cell death // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay" 200005_at NM_003753 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003753.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 7 (zeta, 6667kD) (EIF3S7), mRNA. /FEA=mRNA /GEN=EIF3S7 /PROD=eukaryotic translation initiation factor 3,subunit 7 (zeta, 6667kD) /DB_XREF=gi:4503522 /UG=Hs.55682 eukaryotic translation initiation factor 3, subunit 7 (zeta, 6667kD) /FL=gb:BC000328.1 gb:BC000469.1 gb:U54558.1 gb:NM_003753.1" NM_003753 "eukaryotic translation initiation factor 3, subunit D" EIF3D 8664 NM_003753 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200006_at NM_007262 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007262.1 /DEF=Homo sapiens RNA-binding protein regulatory subunit (DJ-1), mRNA. /FEA=mRNA /GEN=DJ-1 /PROD=RNA-binding protein regulatory subunit /DB_XREF=gi:6005748 /UG=Hs.10958 RNA-binding protein regulatory subunit /FL=gb:AF021819.1 gb:NM_007262.1 gb:D61380.1" NM_007262 parkinson protein 7 PARK7 11315 NM_001123377 /// NM_007262 /// XM_005263424 "0001933 // negative regulation of protein phosphorylation // inferred from genetic interaction /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from genetic interaction /// 0006508 // proteolysis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007338 // single fertilization // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from genetic interaction /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0045560 // regulation of TRAIL receptor biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046826 // negative regulation of protein export from nucleus // inferred from genetic interaction /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051583 // dopamine uptake involved in synaptic transmission // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from direct assay /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0090073 // positive regulation of protein homodimerization activity // inferred from direct assay /// 1900182 // positive regulation of protein localization to nucleus // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from direct assay /// 1901671 // positive regulation of superoxide dismutase activity // inferred from direct assay /// 1901984 // negative regulation of protein acetylation // inferred from direct assay /// 1903073 // negative regulation of death-inducing signaling complex assembly // inferred by curator /// 1903094 // negative regulation of protein K48-linked deubiquitination // inferred from direct assay /// 1903122 // negative regulation of TRAIL-activated apoptotic signaling pathway // inferred from mutant phenotype /// 2000157 // negative regulation of ubiquitin-specific protease activity // inferred from direct assay /// 2000277 // positive regulation of oxidative phosphorylation uncoupler activity // inferred from electronic annotation /// 2000825 // positive regulation of androgen receptor activity // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001268 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005829 // cytosol // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004601 // peroxidase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0016532 // superoxide dismutase copper chaperone activity // inferred from direct assay /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044388 // small protein activating enzyme binding // inferred from physical interaction /// 0044390 // small protein conjugating enzyme binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0051920 // peroxiredoxin activity // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction /// 1903135 // cupric ion binding // inferred from direct assay /// 1903136 // cuprous ion binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction" 200007_at NM_003134 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003134.1 /DEF=Homo sapiens signal recognition particle 14kD (homologous Alu RNA-binding protein) (SRP14), mRNA. /FEA=mRNA /GEN=SRP14 /PROD=signal recognition particle 14kD (homologous AluRNA-binding protein) /DB_XREF=gi:4507210 /UG=Hs.180394 signal recognition particle 14kD (homologous Alu RNA-binding protein) /FL=gb:NM_003134.1 gb:U07857.1" NM_003134 signal recognition particle 14kDa (homologous Alu RNA binding protein) SRP14 6727 NM_003134 /// NR_104021 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045047 // protein targeting to ER // inferred from mutant phenotype "0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0048500 // signal recognition particle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0030942 // endoplasmic reticulum signal peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200008_s_at D13988 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D13988.1 /DEF=Human rab GDI mRNA, complete cds. /FEA=mRNA /PROD=human rab GDI /DB_XREF=gi:285974 /UG=Hs.56845 GDP dissociation inhibitor 2 /FL=gb:BC005145.1 gb:D13988.1 gb:NM_001494.2" D13988 GDP dissociation inhibitor 2 GDI2 2665 NM_001115156 /// NM_001494 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005093 // Rab GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200009_at NM_001494 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001494.2 /DEF=Homo sapiens GDP dissociation inhibitor 2 (GDI2), mRNA. /FEA=mRNA /GEN=GDI2 /PROD=GDP dissociation inhibitor 2 /DB_XREF=gi:6598322 /UG=Hs.56845 GDP dissociation inhibitor 2 /FL=gb:BC005145.1 gb:D13988.1 gb:NM_001494.2" NM_001494 GDP dissociation inhibitor 2 GDI2 2665 NM_001115156 /// NM_001494 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005093 // Rab GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200010_at NM_000975 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000975.1 /DEF=Homo sapiens ribosomal protein L11 (RPL11), mRNA. /FEA=mRNA /GEN=RPL11 /PROD=ribosomal protein L11 /DB_XREF=gi:4506594 /UG=Hs.179943 ribosomal protein L11 /FL=gb:L05092.1 gb:NM_000975.1" NM_000975 ribosomal protein L11 RPL11 6135 NM_000975 /// NM_001199802 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200011_s_at NM_001659 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001659.1 /DEF=Homo sapiens ADP-ribosylation factor 3 (ARF3), mRNA. /FEA=mRNA /GEN=ARF3 /PROD=ADP-ribosylation factor 3 /DB_XREF=gi:4502202 /UG=Hs.119177 ADP-ribosylation factor 3 /FL=gb:M74491.1 gb:NM_001659.1" NM_001659 ADP-ribosylation factor 3 ARF3 377 NM_001659 /// XM_005268856 /// XM_006719391 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 200012_x_at NM_000982 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000982.1 /DEF=Homo sapiens ribosomal protein L21 (gene or pseudogene) (RPL21), mRNA. /FEA=mRNA /GEN=RPL21 /PROD=ribosomal protein L21 (gene or pseudogene) /DB_XREF=gi:4506610 /UG=Hs.184108 ribosomal protein L21 /FL=gb:BC001603.1 gb:NM_000982.1 gb:U14967.1 gb:U25789.1" NM_000982 "ribosomal protein L21 /// ribosomal protein L21 pseudogene 28 /// small nucleolar RNA, H/ACA box 27 /// small nucleolar RNA, C/D box 102" RPL21 /// RPL21P28 /// SNORA27 /// SNORD102 6144 /// 26771 /// 619499 /// 100131205 NM_000982 /// NR_002574 /// NR_002575 /// NR_026911 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200013_at NM_000986 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000986.1 /DEF=Homo sapiens ribosomal protein L24 (RPL24), mRNA. /FEA=mRNA /GEN=RPL24 /PROD=ribosomal protein L24 /DB_XREF=gi:4506618 /UG=Hs.184582 ribosomal protein L24 /FL=gb:BC000690.1 gb:M94314.1 gb:NM_000986.1" NM_000986 ribosomal protein L24 RPL24 6152 NM_000986 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200014_s_at NM_004500 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004500.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein C (C1C2) (HNRPC), mRNA. /FEA=mRNA /GEN=HNRPC /PROD=heterogeneous nuclear ribonucleoprotein C(C1C2) /DB_XREF=gi:4758543 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) /FL=gb:BC003394.1 gb:M16342.1 gb:NM_004500.1" NM_004500 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 /// XM_006720124 /// XM_006720125 /// XM_006720126 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200015_s_at NM_004404 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004404.1 /DEF=Homo sapiens neural precursor cell expressed, developmentally down-regulated 5 (NEDD5), mRNA. /FEA=mRNA /GEN=NEDD5 /PROD=neural precursor cell expressed, developmentallydown-regulated 5 /DB_XREF=gi:4758157 /UG=Hs.155595 neural precursor cell expressed, developmentally down-regulated 5 /FL=gb:D28540.1 gb:NM_004404.1 gb:D63878.1" NM_004404 septin 2 SEPT2 4735 NM_001008491 /// NM_001008492 /// NM_001282972 /// NM_001282973 /// NM_004404 /// NM_006155 /// XM_005247011 /// XM_005247012 /// XM_005247013 /// XM_006712546 /// XM_006712547 /// XM_006712548 /// XM_006712549 /// XM_006712550 0002036 // regulation of L-glutamate transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation "0000145 // exocyst // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation 200016_x_at NM_002136 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002136.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein A1 (HNRPA1), mRNA. /FEA=mRNA /GEN=HNRPA1 /PROD=heterogeneous nuclear ribonucleoprotein A1 /DB_XREF=gi:4504444 /UG=Hs.249495 heterogeneous nuclear ribonucleoprotein A1 /FL=gb:NM_002136.1" NM_002136 heterogeneous nuclear ribonucleoprotein A1 /// heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 HNRNPA1 /// HNRNPA1P10 3178 /// 664709 NM_002136 /// NM_031157 /// NR_002944 /// XM_005268826 /// XR_245923 /// XR_245924 "0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006405 // RNA export from nucleus // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200017_at NM_002954 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002954.1 /DEF=Homo sapiens ribosomal protein S27a (RPS27A), mRNA. /FEA=mRNA /GEN=RPS27A /PROD=ribosomal protein S27a /DB_XREF=gi:4506712 /UG=Hs.3297 ribosomal protein S27a /FL=gb:BC001392.1 gb:BC005328.1 gb:NM_002954.1" NM_002954 ribosomal protein S27a RPS27A 6233 NM_001135592 /// NM_001177413 /// NM_002954 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010992 // ubiquitin homeostasis // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0021888 // hypothalamus gonadotrophin-releasing hormone neuron development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060613 // fat pad development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement /// 0097009 // energy homeostasis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200018_at NM_001017 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001017.1 /DEF=Homo sapiens ribosomal protein S13 (RPS13), mRNA. /FEA=mRNA /GEN=RPS13 /PROD=ribosomal protein S13 /DB_XREF=gi:4506684 /UG=Hs.165590 ribosomal protein S13 /FL=gb:BC000475.1 gb:L01124.1 gb:NM_001017.1" NM_001017 "uncharacterized LOC100508408 /// ribosomal protein S13 /// small nucleolar RNA, C/D box 14B" LOC100508408 /// RPS13 /// SNORD14B 6207 /// 85388 /// 100508408 NM_001017 /// NR_001452 /// XR_111163 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200019_s_at NM_001997 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001997.1 /DEF=Homo sapiens Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 (FAU), mRNA. /FEA=mRNA /GEN=FAU /PROD=Finkel-Biskis-Reilly murine sarcoma virus(FBR-MuSV) ubiquitously expressed (fox derived); ribosomalprotein S30 /DB_XREF=gi:4503658 /UG=Hs.177415 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 /FL=gb:NM_001997.1" NM_001997 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed FAU 2197 NM_001997 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay" 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200020_at NM_007375 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007375.1 /DEF=Homo sapiens TAR DNA binding protein (TARDBP), mRNA. /FEA=mRNA /GEN=TARDBP /PROD=TAR DNA binding protein /DB_XREF=gi:6678270 /UG=Hs.193989 TAR DNA binding protein /FL=gb:AL050265.1 gb:NM_007375.1 gb:U23731.1" NM_007375 TAR DNA binding protein TARDBP 23435 NM_007375 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200021_at NM_005507 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005507.1 /DEF=Homo sapiens cofilin 1 (non-muscle) (CFL1), mRNA. /FEA=mRNA /GEN=CFL1 /PROD=cofilin 1 (non-muscle) /DB_XREF=gi:5031634 /UG=Hs.180370 cofilin 1 (non-muscle) /FL=gb:NM_005507.1" NM_005507 cofilin 1 (non-muscle) CFL1 1072 NM_005507 0000910 // cytokinesis // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001842 // neural fold formation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030042 // actin filament depolymerization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045792 // negative regulation of cell size // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200022_at NM_000979 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000979.1 /DEF=Homo sapiens ribosomal protein L18 (RPL18), mRNA. /FEA=mRNA /GEN=RPL18 /PROD=ribosomal protein L18 /DB_XREF=gi:4506606 /UG=Hs.75458 ribosomal protein L18 /FL=gb:BC000374.1 gb:L11566.1 gb:NM_000979.1" NM_000979 ribosomal protein L18 RPL18 6141 NM_000979 /// NM_001270490 /// NR_073022 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200023_s_at NM_003754 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003754.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) (EIF3S5), mRNA. /FEA=mRNA /GEN=EIF3S5 /PROD=eukaryotic translation initiation factor 3,subunit 5 (epsilon, 47kD) /DB_XREF=gi:4503518 /UG=Hs.7811 eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) /FL=gb:BC000490.1 gb:U94855.1 gb:NM_003754.1" NM_003754 "eukaryotic translation initiation factor 3, subunit F" EIF3F 8665 NM_003754 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200024_at NM_001009 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001009.1 /DEF=Homo sapiens ribosomal protein S5 (RPS5), mRNA. /FEA=mRNA /GEN=RPS5 /PROD=ribosomal protein S5 /DB_XREF=gi:4506728 /UG=Hs.76194 ribosomal protein S5 /FL=gb:NM_001009.1 gb:U14970.1" NM_001009 ribosomal protein S5 RPS5 6193 NM_001009 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from genetic interaction /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006450 // regulation of translational fidelity // inferred from genetic interaction /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200025_s_at NM_000988 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000988.1 /DEF=Homo sapiens ribosomal protein L27 (RPL27), mRNA. /FEA=mRNA /GEN=RPL27 /PROD=ribosomal protein L27 /DB_XREF=gi:4506622 /UG=Hs.111611 ribosomal protein L27 /FL=gb:BC002588.1 gb:L05094.1 gb:L19527.1 gb:NM_000988.1" NM_000988 ribosomal protein L27 RPL27 6155 NM_000988 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200026_at NM_000995 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000995.1 /DEF=Homo sapiens ribosomal protein L34 (RPL34), mRNA. /FEA=mRNA /GEN=RPL34 /PROD=ribosomal protein L34 /DB_XREF=gi:4506636 /UG=Hs.250895 ribosomal protein L34 /FL=gb:L38941.1 gb:BC001773.1 gb:NM_000995.1" NM_000995 ribosomal protein L34 RPL34 6164 NM_000995 /// NM_033625 /// XM_005263172 /// XM_006714287 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200027_at NM_004539 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004539.2 /DEF=Homo sapiens asparaginyl-tRNA synthetase (NARS), mRNA. /FEA=mRNA /GEN=NARS /PROD=asparaginyl-tRNA synthetase /DB_XREF=gi:7262387 /UG=Hs.181311 asparaginyl-tRNA synthetase /FL=gb:BC001687.1 gb:D84273.1 gb:NM_004539.2" NM_004539 asparaginyl-tRNA synthetase NARS 4677 NM_004539 /// XM_005266700 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006421 // asparaginyl-tRNA aminoacylation // inferred from electronic annotation /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0004816 // asparagine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200028_s_at NM_020151 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020151.1 /DEF=Homo sapiens GTT1 protein (GTT1), mRNA. /FEA=mRNA /GEN=GTT1 /PROD=GTT1 protein /DB_XREF=gi:9910251 /UG=Hs.283722 GTT1 protein /FL=gb:AF270647.1 gb:NM_020151.1" NM_020151 StAR-related lipid transfer (START) domain containing 7 STARD7 56910 NM_020151 /// NM_139267 0005739 // mitochondrion // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation 200029_at NM_000981 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000981.1 /DEF=Homo sapiens ribosomal protein L19 (RPL19), mRNA. /FEA=mRNA /GEN=RPL19 /PROD=ribosomal protein L19 /DB_XREF=gi:4506608 /UG=Hs.252723 ribosomal protein L19 /FL=gb:BC000530.1 gb:NM_000981.1" NM_000981 ribosomal protein L19 RPL19 6143 NM_000981 /// XM_005257564 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200030_s_at NM_002635 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002635.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 (SLC25A3), nuclear gene encoding mitochondrial protein, transcript variant 1b, mRNA. /FEA=mRNA /GEN=SLC25A3 /PROD=phosphate carrier precursor isoform 1b /DB_XREF=gi:4505774 /UG=Hs.78713 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 /FL=gb:BC000998.1 gb:BC001328.1 gb:BC003504.1 gb:BC004345.1 gb:NM_002635.1" NM_002635 "solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3" SLC25A3 5250 NM_002635 /// NM_005888 /// NM_213611 /// NM_213612 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006810 // transport // traceable author statement /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015293 // symporter activity // inferred from electronic annotation /// 0015320 // phosphate ion carrier activity // traceable author statement /// 0032403 // protein complex binding // inferred from direct assay 200031_s_at NM_001015 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001015.1 /DEF=Homo sapiens ribosomal protein S11 (RPS11), mRNA. /FEA=mRNA /GEN=RPS11 /PROD=ribosomal protein S11 /DB_XREF=gi:4506680 /UG=Hs.182740 ribosomal protein S11 /FL=gb:NM_001015.1" NM_001015 "ribosomal protein S11 /// small nucleolar RNA, C/D box 35B" RPS11 /// SNORD35B 6205 /// 84546 NM_001015 /// NR_001285 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200032_s_at NM_000661 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000661.1 /DEF=Homo sapiens ribosomal protein L9 (RPL9), mRNA. /FEA=mRNA /GEN=RPL9 /PROD=ribosomal protein L9 /DB_XREF=gi:4506664 /UG=Hs.157850 ribosomal protein L9 /FL=gb:U09953.1 gb:NM_000661.1" NM_000661 ribosomal protein L9 RPL9 6133 NM_000661 /// NM_001024921 /// XM_005262661 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation "0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0047961 // glycine N-acyltransferase activity // inferred from electronic annotation" 200033_at NM_004396 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004396.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 (RNA helicase, 68kD) (DDX5), mRNA. /FEA=mRNA /GEN=DDX5 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 /DB_XREF=gi:13514826 /UG=Hs.76053 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 (RNA helicase, 68kD) /FL=gb:NM_004396.2" NM_004396 DEAD (Asp-Glu-Ala-Asp) box helicase 5 /// microRNA 3064 /// microRNA 5047 DDX5 /// MIR3064 /// MIR5047 1655 /// 100616387 /// 100616408 NM_004396 /// NR_039891 /// NR_039969 /// XM_005257111 /// XM_006721738 /// XR_429871 /// XR_429872 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0060765 // regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // inferred from mutant phenotype /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay" 200034_s_at NM_000970 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000970.1 /DEF=Homo sapiens ribosomal protein L6 (RPL6), mRNA. /FEA=mRNA /GEN=RPL6 /PROD=ribosomal protein L6 /DB_XREF=gi:4506656 /UG=Hs.174131 ribosomal protein L6 /FL=gb:BC004138.1 gb:D17554.1 gb:NM_000970.1 gb:AF261087.1" NM_000970 ribosomal protein L6 RPL6 6128 NM_000970 /// NM_001024662 /// XM_005253920 /// XM_006719546 /// XM_006719547 /// XM_006719548 /// XM_006719549 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200035_at NM_015343 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015343.1 /DEF=Homo sapiens hypothetical protein (HSA011916), mRNA. /FEA=mRNA /GEN=HSA011916 /PROD=hypothetical protein /DB_XREF=gi:7661721 /UG=Hs.84359 hypothetical protein /FL=gb:NM_015343.1" NM_015343 CTD nuclear envelope phosphatase 1 CTDNEP1 23399 NM_001143775 /// NM_015343 0006470 // protein dephosphorylation // inferred from direct assay /// 0006998 // nuclear envelope organization // inferred from direct assay /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from genetic interaction /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0071595 // Nem1-Spo7 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200036_s_at NM_007104 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007104.2 /DEF=Homo sapiens ribosomal protein L10a (RPL10A), mRNA. /FEA=mRNA /GEN=RPL10A /PROD=ribosomal protein L10a /DB_XREF=gi:6325471 /UG=Hs.252574 ribosomal protein L10a /FL=gb:U12404.1 gb:NM_007104.2" NM_007104 ribosomal protein L10a RPL10A 4736 NM_007104 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200037_s_at NM_016587 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016587.1 /DEF=Homo sapiens heterochromatin-like protein 1 (HECH), mRNA. /FEA=mRNA /GEN=HECH /PROD=heterochromatin-like protein 1 /DB_XREF=gi:7705406 /UG=Hs.278554 heterochromatin-like protein 1 /FL=gb:AF136630.1 gb:NM_016587.1" NM_016587 chromobox homolog 3 CBX3 11335 NM_007276 /// NM_016587 /// XM_005249611 /// XM_005249612 "0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation" "0000779 // condensed chromosome, centromeric region // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005637 // nuclear inner membrane // non-traceable author statement /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0031618 // nuclear centromeric heterochromatin // inferred from sequence or structural similarity" 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 1990226 // histone methyltransferase binding // inferred from physical interaction 200038_s_at NM_000985 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000985.1 /DEF=Homo sapiens ribosomal protein L17 (RPL17), mRNA. /FEA=mRNA /GEN=RPL17 /PROD=ribosomal protein L17 /DB_XREF=gi:4506616 /UG=Hs.82202 ribosomal protein L17 /FL=gb:BC000502.1 gb:NM_000985.1" NM_000985 "chromosome 18 open reading frame 32 /// ribosomal protein L17 /// RPL17-C18orf32 readthrough /// small nucleolar RNA, C/D box 58A /// small nucleolar RNA, C/D box 58B /// small nucleolar RNA, C/D box 58C" C18orf32 /// RPL17 /// RPL17-C18orf32 /// SNORD58A /// SNORD58B /// SNORD58C 6139 /// 26790 /// 26791 /// 497661 /// 100124516 /// 100526842 NM_000985 /// NM_001035005 /// NM_001035006 /// NM_001199340 /// NM_001199341 /// NM_001199342 /// NM_001199343 /// NM_001199344 /// NM_001199345 /// NM_001199346 /// NM_001199355 /// NM_001199356 /// NR_002571 /// NR_002572 /// NR_003701 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay 200039_s_at NM_002794 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002794.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 2 (PSMB2), mRNA. /FEA=mRNA /GEN=PSMB2 /PROD=proteasome (prosome, macropain) subunit, betatype, 2 /DB_XREF=gi:4506194 /UG=Hs.1390 proteasome (prosome, macropain) subunit, beta type, 2 /FL=gb:BC000268.1 gb:NM_002794.1 gb:D26599.1" NM_002794 "proteasome (prosome, macropain) subunit, beta type, 2" PSMB2 5690 NM_001199779 /// NM_001199780 /// NM_002794 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200040_at NM_006559 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006559.1 /DEF=Homo sapiens GAP-associated tyrosine phosphoprotein p62 (Sam68) (SAM68), mRNA. /FEA=mRNA /GEN=SAM68 /PROD=GAP-associated tyrosine phosphoprotein p62(Sam68) /DB_XREF=gi:5730026 /UG=Hs.119537 GAP-associated tyrosine phosphoprotein p62 (Sam68) /FL=gb:BC000717.1 gb:M88108.1 gb:NM_006559.1" NM_006559 "KH domain containing, RNA binding, signal transduction associated 1" KHDRBS1 10657 NM_001271878 /// NM_006559 /// NR_073498 /// NR_073499 "0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from physical interaction /// 0031647 // regulation of protein stability // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045948 // positive regulation of translational initiation // inferred from direct assay /// 0046831 // regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0046833 // positive regulation of RNA export from nucleus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070618 // Grb2-Sos complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200041_s_at NM_004640 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004640.1 /DEF=Homo sapiens HLA-B associated transcript-1 (D6S81E), mRNA. /FEA=mRNA /GEN=D6S81E /PROD=HLA-B associated transcript-1 /DB_XREF=gi:4758111 /UG=Hs.55296 HLA-B associated transcript-1 /FL=gb:BC004350.1 gb:NM_004640.1" NM_004640 "ATP6V1G2-DDX39B readthrough (NMD candidate) /// DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B /// small nucleolar RNA, C/D box 84" ATP6V1G2-DDX39B /// DDX39B /// SNORD84 7919 /// 692199 /// 100532737 NM_004640 /// NM_080598 /// NR_003065 /// NR_037852 /// NR_037853 "0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype" 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005688 // U6 snRNP // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008186 // RNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0030621 // U4 snRNA binding // inferred from direct assay /// 0043008 // ATP-dependent protein binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay" 200042_at NM_014306 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014306.1 /DEF=Homo sapiens hypothetical protein (HSPC117), mRNA. /FEA=mRNA /GEN=HSPC117 /PROD=similar to C. elegens hypothetical 55.2 kDprotein F16A11.2 /DB_XREF=gi:7657014 /UG=Hs.10729 hypothetical protein /FL=gb:BC000151.1 gb:BC002970.1 gb:AF161466.1 gb:NM_014306.1 gb:AF155658.1" NM_014306 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" RTCB 51493 NM_014306 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from direct assay /// 0006396 // RNA processing // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // non-traceable author statement" 0005737 // cytoplasm // inferred from electronic annotation /// 0072669 // tRNA-splicing ligase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003972 // RNA ligase (ATP) activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008452 // RNA ligase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200043_at NM_004450 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004450.1 /DEF=Homo sapiens enhancer of rudimentary (Drosophila) homolog (ERH), mRNA. /FEA=mRNA /GEN=ERH /PROD=enhancer of rudimentary (Drosophila) homolog /DB_XREF=gi:4758301 /UG=Hs.118757 enhancer of rudimentary (Drosophila) homolog /FL=gb:D85758.1 gb:U66871.1 gb:NM_004450.1" NM_004450 enhancer of rudimentary homolog (Drosophila) ERH 2079 NM_004450 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006213 // pyrimidine nucleoside metabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0030496 // midbody // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 200044_at NM_003769 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003769.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 9 (SFRS9), mRNA. /FEA=mRNA /GEN=SFRS9 /PROD=splicing factor, arginineserine-rich 9 /DB_XREF=gi:4506902 /UG=Hs.77608 splicing factor, arginineserine-rich 9 /FL=gb:U30825.1 gb:NM_003769.1" NM_003769 "glutamyl-tRNA(Gln) amidotransferase, subunit C /// serine/arginine-rich splicing factor 9" GATC /// SRSF9 8683 /// 283459 NM_003769 /// NM_176818 /// NR_033684 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay" 200045_at NM_001090 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001090.1 /DEF=Homo sapiens ATP-binding cassette, sub-family F (GCN20), member 1 (ABCF1), mRNA. /FEA=mRNA /GEN=ABCF1 /PROD=ATP-binding cassette, sub-family F, member 1 /DB_XREF=gi:10947134 /UG=Hs.9573 ATP-binding cassette, sub-family F (GCN20), member 1 /FL=gb:NM_001090.1 gb:AF027302.1" NM_001090 "ATP-binding cassette, sub-family F (GCN20), member 1" ABCF1 23 NM_001025091 /// NM_001090 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from mutant phenotype /// 0006954 // inflammatory response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042788 // polysomal ribosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0008494 // translation activator activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay" 200046_at NM_001344 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001344.1 /DEF=Homo sapiens defender against cell death 1 (DAD1), mRNA. /FEA=mRNA /GEN=DAD1 /PROD=defender against cell death 1 /DB_XREF=gi:4503252 /UG=Hs.82890 defender against cell death 1 /FL=gb:NM_001344.1 gb:D15057.1" NM_001344 defender against cell death 1 DAD1 1603 NM_001344 0001824 // blastocyst development // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred by curator /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004576 // oligosaccharyl transferase activity // inferred from sequence or structural similarity /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred by curator /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation" 200047_s_at NM_003403 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003403.2 /DEF=Homo sapiens YY1 transcription factor (YY1), mRNA. /FEA=mRNA /GEN=YY1 /PROD=YY1 transcription factor /DB_XREF=gi:6042207 /UG=Hs.97496 YY1 transcription factor /FL=gb:M77698.1 gb:M76541.1 gb:NM_003403.2" NM_003403 YY1 transcription factor YY1 7528 NM_003403 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006403 // RNA localization // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from electronic annotation 0000400 // four-way junction DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200048_s_at NM_006694 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006694.1 /DEF=Homo sapiens jumping translocation breakpoint (JTB), mRNA. /FEA=mRNA /GEN=JTB /PROD=jumping translocation breakpoint /DB_XREF=gi:5729888 /UG=Hs.6396 jumping translocation breakpoint /FL=gb:BC000499.1 gb:BC001363.1 gb:BC000996.2 gb:BC001667.1 gb:AB016488.1 gb:AF131797.1 gb:NM_006694.1 gb:AF115850.2" NM_006694 jumping translocation breakpoint JTB 10899 NM_006694 0000910 // cytokinesis // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0019901 // protein kinase binding // inferred from direct assay 200049_at NM_007067 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007067.1 /DEF=Homo sapiens histone acetyltransferase (HBOA), mRNA. /FEA=mRNA /GEN=HBOA /PROD=histone acetyltransferase /DB_XREF=gi:5901961 /UG=Hs.21907 histone acetyltransferase /FL=gb:AF074606.1 gb:AF140360.1 gb:NM_007067.1" NM_007067 K(lysine) acetyltransferase 7 KAT7 11143 NM_001199155 /// NM_001199156 /// NM_001199157 /// NM_001199158 /// NM_007067 "0006260 // DNA replication // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay" 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 200050_at NM_007145 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007145.1 /DEF=Homo sapiens zinc finger protein 146 (ZNF146), mRNA. /FEA=mRNA /GEN=ZNF146 /PROD=zinc finger protein 146 /DB_XREF=gi:6005965 /UG=Hs.301819 zinc finger protein 146 /FL=gb:BC005154.1 gb:NM_007145.1" NM_007145 zinc finger protein 146 ZNF146 7705 NM_001099638 /// NM_001099639 /// NM_007145 /// XM_005259214 "0006355 // regulation of transcription, DNA-templated // not recorded" 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // not recorded /// 0008201 // heparin binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200051_at NM_005146 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005146.1 /DEF=Homo sapiens squamous cell carcinoma antigen recognised by T cells (SART1), mRNA. /FEA=mRNA /GEN=SART1 /PROD=squamous cell carcinoma antigen recognised by Tcells /DB_XREF=gi:10863888 /UG=Hs.288319 squamous cell carcinoma antigen recognised by T cells /FL=gb:NM_005146.1 gb:BC001058.1 gb:AB006198.1" NM_005146 squamous cell carcinoma antigen recognized by T cells SART1 9092 NM_005146 "0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007050 // cell cycle arrest // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045585 // positive regulation of cytotoxic T cell differentiation // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // non-traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200052_s_at NM_004515 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004515.1 /DEF=Homo sapiens interleukin enhancer binding factor 2, 45kD (ILF2), mRNA. /FEA=mRNA /GEN=ILF2 /PROD=interleukin enhancer binding factor 2, 45kD /DB_XREF=gi:4758601 /UG=Hs.75117 interleukin enhancer binding factor 2, 45kD /FL=gb:BC000382.1 gb:NM_004515.1 gb:U10323.1" NM_004515 interleukin enhancer binding factor 2 ILF2 3608 NM_001267809 /// NM_004515 "0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200053_at NM_004890 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004890.1 /DEF=Homo sapiens sperm associated antigen 7 (SPAG7), mRNA. /FEA=mRNA /GEN=SPAG7 /PROD=sperm associated antigen 7 /DB_XREF=gi:4757715 /UG=Hs.90436 sperm associated antigen 7 /FL=gb:AF047437.1 gb:NM_004890.1" NM_004890 sperm associated antigen 7 SPAG7 9552 NM_004890 /// XM_005256865 /// XM_006721600 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation 200054_at NM_003904 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003904.1 /DEF=Homo sapiens zinc finger protein 259 (ZNF259), mRNA. /FEA=mRNA /GEN=ZNF259 /PROD=zinc finger protein 259 /DB_XREF=gi:4508020 /UG=Hs.7165 zinc finger protein 259 /FL=gb:BC004256.1 gb:AF019767.1 gb:NM_003904.1" NM_003904 ZPR1 zinc finger ZPR1 8882 NM_003904 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0001834 // trophectodermal cell proliferation // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030576 // Cajal body organization // inferred from mutant phenotype /// 0030576 // Cajal body organization // inferred from sequence or structural similarity /// 0031641 // regulation of myelination // inferred from sequence or structural similarity /// 0033120 // positive regulation of RNA splicing // inferred from mutant phenotype /// 0042023 // DNA endoreduplication // inferred from sequence or structural similarity /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0045927 // positive regulation of growth // inferred from sequence or structural similarity /// 0061564 // axon development // inferred from mutant phenotype /// 0061564 // axon development // inferred from sequence or structural similarity /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 1902742 // apoptotic process involved in development // inferred from sequence or structural similarity /// 1990261 // pre-mRNA catabolic process // inferred from mutant phenotype /// 2000672 // negative regulation of motor neuron apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0032797 // SMN complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031369 // translation initiation factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200055_at NM_006284 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006284.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD (TAF2H), mRNA. /FEA=mRNA /GEN=TAF2H /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, H, 30kD /DB_XREF=gi:5454105 /UG=Hs.89657 TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD /FL=gb:NM_006284.1 gb:U13991.1" NM_006284 "TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa" TAF10 6881 NM_006284 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred by curator /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016578 // histone deubiquitination // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay" 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from direct assay 200056_s_at NM_006333 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006333.1 /DEF=Homo sapiens nuclear DNA-binding protein (C1D), mRNA. /FEA=mRNA /GEN=C1D /PROD=nuclear DNA-binding protein /DB_XREF=gi:5453582 /UG=Hs.15164 nuclear DNA-binding protein /FL=gb:NM_006333.1" NM_006333 C1D nuclear receptor corepressor C1D 10438 NM_001190263 /// NM_001190265 /// NM_006333 /// NM_173177 "0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation" 0000176 // nuclear exosome (RNase complex) // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation 200057_s_at NM_007363 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007363.2 /DEF=Homo sapiens non-POU-domain-containing, octamer-binding (NONO), mRNA. /FEA=mRNA /GEN=NONO /PROD=non-Pou domain-containing octamer (ATGCAAAT)binding protein /DB_XREF=gi:7657382 /UG=Hs.172207 non-POU-domain-containing, octamer-binding /FL=gb:NM_007363.2" NM_007363 "non-POU domain containing, octamer-binding" NONO 4841 NM_001145408 /// NM_001145409 /// NM_001145410 /// NM_007363 "0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200058_s_at BC001417 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001417.1 /DEF=Homo sapiens, Similar to U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family), clone MGC:2580, mRNA, complete cds. /FEA=mRNA /PROD=Similar to U5 snRNP-specific protein, 200 kDa(DEXH RNA helicase family) /DB_XREF=gi:12655128 /UG=Hs.246112 KIAA0788 protein /FL=gb:BC001417.1 gb:AF119874.1" BC001417 U5 small nuclear ribonucleoprotein 200 kDa helicase-like /// small nuclear ribonucleoprotein 200kDa (U5) LOC101929240 /// SNRNP200 23020 /// 101929240 NM_014014 /// XR_243770 /// XR_253745 /// XR_424859 "0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200059_s_at BC001360 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001360.1 /DEF=Homo sapiens, ras homolog gene family, member A, clone MGC:2330, mRNA, complete cds. /FEA=mRNA /PROD=ras homolog gene family, member A /DB_XREF=gi:12655024 /UG=Hs.77273 ras homolog gene family, member A /FL=gb:NM_001664.1 gb:BC001360.1 gb:L25080.1" BC001360 ras homolog family member A RHOA 387 NM_001664 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008064 // regulation of actin polymerization or depolymerization // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031098 // stress-activated protein kinase signaling cascade // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0033688 // regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0036089 // cleavage furrow formation // inferred from direct assay /// 0042346 // positive regulation of NF-kappaB import into nucleus // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043931 // ossification involved in bone maturation // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0061383 // trabecula morphogenesis // inferred from sequence or structural similarity /// 0071803 // positive regulation of podosome assembly // inferred from electronic annotation /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200060_s_at BC001659 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001659.1 /DEF=Homo sapiens, RNA-binding protein S1, serine-rich domain, clone MGC:1125, mRNA, complete cds. /FEA=mRNA /PROD=RNA-binding protein S1, serine-rich domain /DB_XREF=gi:12804496 /UG=Hs.75104 RNA-binding protein S1, serine-rich domain /FL=gb:BC001659.1 gb:BC001838.1" BC001659 "RNA binding protein S1, serine-rich domain" RNPS1 10921 NM_001286625 /// NM_001286626 /// NM_001286627 /// NM_006711 /// NM_080594 /// NR_104485 /// XM_005255048 /// XM_005255049 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // traceable author statement /// 0061574 // ASAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // non-traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200061_s_at BC000523 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000523.1 /DEF=Homo sapiens, Similar to ribosomal protein S24, clone MGC:8595, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein S24 /DB_XREF=gi:12653502 /UG=Hs.180450 ribosomal protein S24 /FL=gb:BC000523.1 gb:BC003149.1" BC000523 ribosomal protein S24 RPS24 6229 NM_001026 /// NM_001142282 /// NM_001142283 /// NM_001142284 /// NM_001142285 /// NM_033022 /// XM_006717938 /// XR_428711 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0015935 // small ribosomal subunit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 200062_s_at L05095 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L05095.1 /DEF=Homo sapiens ribosomal protein L30 mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L30 /DB_XREF=gi:388034 /UG=Hs.111222 ribosomal protein L30 /FL=gb:L05095.1 gb:NM_000989.1" L05095 ribosomal protein L30 RPL30 6156 NM_000989 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200063_s_at BC002398 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002398.1 /DEF=Homo sapiens, nucleophosmin (nucleolar phosphoprotein B23, numatrin), clone MGC:8463, mRNA, complete cds. /FEA=mRNA /PROD=nucleophosmin (nucleolar phosphoprotein B23,numatrin) /DB_XREF=gi:12803184 /UG=Hs.9614 nucleophosmin (nucleolar phosphoprotein B23, numatrin) /FL=gb:NM_002520.1 gb:BC002398.1 gb:BC003670.1 gb:M23613.1 gb:M26697.1 gb:M28699.1" BC002398 "nucleophosmin (nucleolar phosphoprotein B23, numatrin)" NPM1 4869 NM_001037738 /// NM_002520 /// NM_199185 /// XM_005265920 /// XM_006714869 0006281 // DNA repair // inferred from direct assay /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032071 // regulation of endodeoxyribonuclease activity // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0042255 // ribosome assembly // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0060699 // regulation of endoribonuclease activity // inferred from direct assay /// 0060735 // regulation of eIF2 alpha phosphorylation by dsRNA // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043023 // ribosomal large subunit binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 200064_at AF275719 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF275719.1 /DEF=Homo sapiens isolate Liv chaperone protein HSP90 beta (HSP90BETA) mRNA, complete cds. /FEA=mRNA /GEN=HSP90BETA /PROD=chaperone protein HSP90 beta /DB_XREF=gi:9082288 /UG=Hs.74335 heat shock 90kD protein 1, beta /FL=gb:BC004928.1 gb:M16660.1 gb:NM_007355.1 gb:AF275719.1" AF275719 "heat shock protein 90kDa alpha (cytosolic), class B member 1" HSP90AB1 3326 NM_001271969 /// NM_001271970 /// NM_001271971 /// NM_001271972 /// NM_007355 /// NR_073528 /// XM_005249075 "0001890 // placenta development // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009651 // response to salt stress // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // inferred from mutant phenotype /// 0060338 // regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002134 // UTP binding // inferred from electronic annotation /// 0002135 // CTP binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017098 // sulfonylurea receptor binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030235 // nitric-oxide synthase regulator activity // inferred from sequence or structural similarity /// 0030911 // TPR domain binding // inferred from sequence or structural similarity /// 0032564 // dATP binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200065_s_at AF052179 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF052179.1 /DEF=Homo sapiens clone 24537 ADP-ribosylation factor 1 mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor 1 /DB_XREF=gi:3360490 /UG=Hs.74571 ADP-ribosylation factor 1 /FL=gb:M84326.1 gb:M36340.1 gb:AF055002.1 gb:AF052179.1 gb:NM_001658.2" AF052179 ADP-ribosylation factor 1 /// microRNA 3620 ARF1 /// MIR3620 375 /// 100500810 NM_001024226 /// NM_001024227 /// NM_001024228 /// NM_001658 /// NR_037415 "0002090 // regulation of receptor internalization // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0034315 // regulation of Arp2/3 complex-mediated actin nucleation // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0061024 // membrane organization // traceable author statement /// 0097061 // dendritic spine organization // inferred from sequence or structural similarity" 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200066_at AF182645 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF182645.1 /DEF=Homo sapiens chondrosarcoma-associated protein 2 (CSA2) mRNA, complete cds. /FEA=mRNA /GEN=CSA2 /PROD=chondrosarcoma-associated protein 2 /DB_XREF=gi:5901877 /UG=Hs.8024 IK cytokine, down-regulator of HLA II /FL=gb:NM_006083.2 gb:AF182645.1" AF182645 "IK cytokine, down-regulator of HLA II" IK 3550 NM_006083 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 200067_x_at AL078596 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL078596 /DEF=Human DNA sequence from clone RP3-429G5 on chromosome 6q21-22.1. Contains the NR2E1 gene for nuclear receptor 2E1 (tailless, TLL, TLX, XTLL), the 3 end of the SNX3 gene for sorting nexin 3, ESTs, STSs, GSSs and four predicted CpG islands /FEA=mRNA_2 /DB_XREF=gi:6010168 /UG=Hs.12102 sorting nexin 3 /FL=gb:AF062483.1 gb:AF034546.1 gb:NM_003795.1" AL078596 sorting nexin 3 SNX3 8724 NM_003795 /// NM_152827 /// NM_152828 /// XM_005267192 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // not recorded 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 200068_s_at M94859 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M94859.1 /DEF=Human calnexin mRNA, complete cds. /FEA=mRNA /PROD=calnexin /DB_XREF=gi:179831 /UG=Hs.155560 calnexin /FL=gb:NM_001746.1 gb:BC003552.1 gb:M94859.1 gb:M98452.1 gb:L10284.1 gb:L18887.1" M94859 calnexin CANX 821 NM_001024649 /// NM_001746 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048488 // synaptic vesicle endocytosis // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0072583 // clathrin-mediated endocytosis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 200069_at AI656011 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI656011 /FEA=EST /DB_XREF=gi:4739990 /DB_XREF=est:tt42e08.x1 /CLONE=IMAGE:2243462 /UG=Hs.116875 KIAA0156 gene product /FL=gb:AB020880.1 gb:NM_014706.1 gb:D63879.1 AI656011 squamous cell carcinoma antigen recognized by T cells 3 SART3 9733 NM_014706 /// XM_005269241 0006396 // RNA processing // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200070_at BC001393 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001393.1 /DEF=Homo sapiens, hypothetical protein, clone MGC:782, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:12655084 /UG=Hs.4973 hypothetical protein /FL=gb:BC001393.1" BC001393 cyclin Pas1/PHO80 domain containing 1 CNPPD1 27013 NM_015680 /// XM_005246462 /// XM_005246463 /// XM_006712419 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019901 // protein kinase binding // inferred from electronic annotation 200071_at BF224259 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF224259 /FEA=EST /DB_XREF=gi:11131523 /DB_XREF=est:7q85c09.x1 /CLONE=IMAGE:3705208 /UG=Hs.79968 splicing factor 30, survival of motor neuron-related /FL=gb:AF083385.1 gb:AF107463.1 gb:NM_005871.1" BF224259 survival motor neuron domain containing 1 SMNDC1 10285 NM_005871 /// XM_005269382 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200072_s_at AF061832 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF061832.1 /DEF=Homo sapiens M4 protein deletion mutant mRNA, complete cds. /FEA=mRNA /PROD=M4 protein deletion mutant /DB_XREF=gi:3126877 /UG=Hs.79024 heterogeneous nuclear ribonucleoprotein M /FL=gb:AF061832.1" AF061832 heterogeneous nuclear ribonucleoprotein M HNRNPM 4670 NM_001297418 /// NM_005968 /// NM_031203 /// XM_005272478 /// XM_005272479 /// XM_005272480 /// XM_005272481 /// XM_005272482 /// XM_005272483 "0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042382 // paraspeckles // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200073_s_at M94630 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M94630.1 /DEF=Homo sapiens hnRNP-C like protein mRNA, complete cds. /FEA=mRNA /PROD=DNA-binding protein /DB_XREF=gi:181913 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) /FL=gb:M94630.1" M94630 "heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)" HNRNPD 3184 NM_001003810 /// NM_002138 /// NM_031369 /// NM_031370 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0097167 // circadian regulation of translation // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200074_s_at U16738 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U16738.1 /DEF=Homo sapiens CAG-isl 7 mRNA, complete cds. /FEA=mRNA /PROD=CAG-isl 7 /DB_XREF=gi:608516 /UG=Hs.738 ribosomal protein L14 /FL=gb:U16738.1" U16738 ribosomal protein L14 RPL14 9045 NM_001034996 /// NM_003973 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200075_s_at BC006249 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC006249.1 /DEF=Homo sapiens, guanylate kinase 1, clone MGC:10618, mRNA, complete cds. /FEA=mRNA /PROD=guanylate kinase 1 /DB_XREF=gi:13623296 /FL=gb:BC006249.1" BC006249 guanylate kinase 1 GUK1 2987 NM_000858 /// NM_001159390 /// NM_001159391 /// NM_001242839 /// NM_001242840 /// XM_005273103 /// XM_005273104 /// XM_005273105 /// XM_005273106 0006163 // purine nucleotide metabolic process // inferred from direct assay /// 0006185 // dGDP biosynthetic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017144 // drug metabolic process // traceable author statement /// 0019673 // GDP-mannose metabolic process // inferred from electronic annotation /// 0034436 // glycoprotein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046037 // GMP metabolic process // inferred from electronic annotation /// 0046054 // dGMP metabolic process // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046711 // GDP biosynthetic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004385 // guanylate kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200076_s_at BC006479 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC006479.1 /DEF=Homo sapiens, hypothetical protein MGC2749, clone MGC:4376, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein MGC2749 /DB_XREF=gi:13623702 /FL=gb:BC006479.1" BC006479 KxDL motif containing 1 KXD1 79036 NM_001171948 /// NM_001171949 /// NM_024069 /// XM_005260073 /// XM_006722883 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity 0031083 // BLOC-1 complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 200077_s_at D87914 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D87914.1 /DEF=Human mRNA for ornithine decarboxylase antizyme, complete cds. /FEA=mRNA /GEN=hAZ-brain /PROD=ornithine decarboxylase antizyme /DB_XREF=gi:1590807 /FL=gb:D87914.1" D87914 ornithine decarboxylase antizyme 1 OAZ1 4946 NM_004152 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 200078_s_at BC005876 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005876.1 /DEF=Homo sapiens, ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD, clone MGC:4498, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 21kD /DB_XREF=gi:13543437 /FL=gb:BC005876.1" BC005876 "ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b" ATP6V0B 533 NM_001039457 /// NM_001294333 /// NM_004047 /// XM_005270944 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005768 // endosome // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation" 0005215 // transporter activity // traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 200079_s_at AF285758 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF285758.1 /DEF=Homo sapiens lysyl-tRNA synthetase mRNA, complete cds; nuclear gene for mitochondrial product; alternatively spliced. /FEA=CDS /PROD=lysyl-tRNA synthetase /DB_XREF=gi:11095908 /UG=Hs.3100 lysyl-tRNA synthetase /FL=gb:AF285758.1" AF285758 lysyl-tRNA synthetase KARS 3735 NM_001130089 /// NM_005548 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006430 // lysyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015966 // diadenosine tetraphosphate biosynthetic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from electronic annotation 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // inferred from direct assay /// 0004824 // lysine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200080_s_at AI955655 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI955655 /FEA=EST /DB_XREF=gi:5747965 /DB_XREF=est:wt36f03.x1 /CLONE=IMAGE:2509565 /UG=Hs.181307 H3 histone, family 3A" AI955655 "H3 histone, family 3A /// H3 histone, family 3A, pseudogene 4 /// H3 histone, family 3B (H3.3B)" H3F3A /// H3F3AP4 /// H3F3B 3020 /// 3021 /// 440926 NM_002107 /// NM_005324 /// NR_002315 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype 0000228 // nuclear chromosome // inferred from direct assay /// 0000786 // nucleosome // inferred from electronic annotation /// 0000788 // nuclear nucleosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200081_s_at BE741754 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE741754 /FEA=EST /DB_XREF=gi:10155746 /DB_XREF=est:601595220F1 /CLONE=IMAGE:3949109 /UG=Hs.241507 ribosomal protein S6 BE741754 ribosomal protein S6 RPS6 6194 NM_001010 "0000028 // ribosomal small subunit assembly // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0031929 // TOR signaling // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200082_s_at AI805587 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI805587 /FEA=EST /DB_XREF=gi:5392153 /DB_XREF=est:tx97a02.x1 /CLONE=IMAGE:2277482 /UG=Hs.301547 ribosomal protein S7 AI805587 ribosomal protein S7 RPS7 6201 NM_001011 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030686 // 90S preribosome // not recorded /// 0032040 // small-subunit processome // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200083_at AA621731 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA621731 /FEA=EST /DB_XREF=gi:2525670 /DB_XREF=est:af54h05.s1 /CLONE=IMAGE:1035513 /UG=Hs.12064 ubiquitin specific protease 22 AA621731 ubiquitin specific peptidase 22 USP22 23326 NM_015276 /// XM_005256575 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0016578 // histone deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype" 0000124 // SAGA complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0070461 // SAGA-type complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200084_at BE748698 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE748698 /FEA=EST /DB_XREF=gi:10162690 /DB_XREF=est:601571740T1 /CLONE=IMAGE:3838712 /UG=Hs.78050 small acidic protein BE748698 chromosome 11 open reading frame 58 C11orf58 10944 NM_001142705 /// NM_014267 200085_s_at NM_007108 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:NM_007108.1 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) (TCEB2), mRNA. /FEA=CDS /GEN=TCEB2 /PROD=elongin B /DB_XREF=gi:6005889 /UG=Hs.172772 transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) /FL=gb:NM_007108.1 gb:L42856.1" NM_007108 "transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)" TCEB2 6923 NM_007108 /// NM_207013 /// XM_006720937 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070449 // elongin complex // inferred from electronic annotation 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 200086_s_at AA854966 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA854966 /FEA=EST /DB_XREF=gi:2942504 /DB_XREF=est:aj70d12.s1 /CLONE=IMAGE:1401815 /UG=Hs.113205 cytochrome c oxidase subunit IV AA854966 cytochrome c oxidase subunit IV isoform 1 COX4I1 1327 NM_001861 /// XM_005255798 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200087_s_at AK024976 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK024976.1 /DEF=Homo sapiens cDNA: FLJ21323 fis, clone COL02374. /FEA=mRNA /DB_XREF=gi:10437405 /UG=Hs.75914 Homo sapiens cDNA: FLJ21323 fis, clone COL02374" AK024976 transmembrane emp24 domain trafficking protein 2 TMED2 10959 NM_006815 /// XM_005253544 0001893 // maternal placenta development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0035459 // cargo loading into vesicle // traceable author statement /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200088_x_at AK026491 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK026491.1 /DEF=Homo sapiens cDNA: FLJ22838 fis, clone KAIA4494, highly similar to HUML12A Human ribosomal protein L12 mRNA. /FEA=mRNA /DB_XREF=gi:10439364 /UG=Hs.182979 ribosomal protein L12" AK026491 neurobeachin-like 1 /// ribosomal protein L12 NBEAL1 /// RPL12 6136 /// 65065 NM_000976 /// NM_001099273 /// NM_001114132 /// NM_198945 /// NM_205543 /// XM_005246787 /// XM_005246788 /// XM_006712698 /// XM_006712699 /// XM_006712700 /// XM_006712701 /// XM_006712702 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200089_s_at AI953886 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI953886 /FEA=EST /DB_XREF=gi:5746196 /DB_XREF=est:wx70g02.x1 /CLONE=IMAGE:2549042 /UG=Hs.286 ribosomal protein L4 AI953886 "ribosomal protein L4 /// small nucleolar RNA, C/D box 16 /// small nucleolar RNA, C/D box 18A /// small nucleolar RNA, C/D box 18B /// small nucleolar RNA, C/D box 18C" RPL4 /// SNORD16 /// SNORD18A /// SNORD18B /// SNORD18C 6124 /// 595097 /// 595098 /// 595099 /// 595100 NM_000968 /// NR_002440 /// NR_002441 /// NR_002442 /// NR_002443 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200090_at BG168896 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG168896 /FEA=EST /DB_XREF=gi:12675599 /DB_XREF=est:602320235F1 /CLONE=IMAGE:4415240 /UG=Hs.138381 farnesyltransferase, CAAX box, alpha" BG168896 "farnesyltransferase, CAAX box, alpha" FNTA 2339 NM_001018676 /// NM_001018677 /// NM_002027 /// NR_033698 "0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0018342 // protein prenylation // inferred from electronic annotation /// 0018343 // protein farnesylation // inferred from direct assay /// 0018344 // protein geranylgeranylation // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0090044 // positive regulation of tubulin deacetylation // inferred from direct assay /// 0090045 // positive regulation of deacetylase activity // inferred from direct assay" 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005953 // CAAX-protein geranylgeranyltransferase complex // inferred from direct assay /// 0005965 // protein farnesyltransferase complex // inferred from direct assay 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // inferred from direct assay /// 0004661 // protein geranylgeranyltransferase activity // inferred from direct assay /// 0004662 // CAAX-protein geranylgeranyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 200091_s_at AA888388 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA888388 /FEA=EST /DB_XREF=gi:3004063 /DB_XREF=est:nw79f03.s1 /CLONE=IMAGE:1252829 /UG=Hs.113029 ribosomal protein S25 AA888388 ribosomal protein S25 RPS25 6230 NM_001028 "0000028 // ribosomal small subunit assembly // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200092_s_at BF216701 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF216701 /FEA=EST /DB_XREF=gi:11110287 /DB_XREF=est:601884615F1 /CLONE=IMAGE:4103235 /UG=Hs.179779 ribosomal protein L37 BF216701 ribosomal protein L37 RPL37 6167 NM_000997 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0019843 // rRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200093_s_at N32864 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N32864 /FEA=EST /DB_XREF=gi:1153263 /DB_XREF=est:yw88d08.s1 /CLONE=IMAGE:259311 /UG=Hs.256697 histidine triad nucleotide-binding protein N32864 histidine triad nucleotide binding protein 1 HINT1 3094 NM_005340 /// NR_024610 /// NR_024611 /// NR_073488 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009154 // purine ribonucleotide catabolic process // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype" 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0016787 // hydrolase activity // inferred from direct assay 200094_s_at AI004246 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI004246 /FEA=EST /DB_XREF=gi:3213756 /DB_XREF=est:ou03g06.x1 /CLONE=IMAGE:1625242 /UG=Hs.75309 eukaryotic translation elongation factor 2 AI004246 eukaryotic translation elongation factor 2 EEF2 1938 NM_001961 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008494 // translation activator activity // inferred from genetic interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200095_x_at AA320764 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA320764 /FEA=EST /DB_XREF=gi:1973113 /DB_XREF=est:EST23183 /UG=Hs.76230 ribosomal protein S10 AA320764 ribosomal protein S10 RPS10 6204 NM_001014 /// NM_001203245 /// NM_001204091 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015961 // diadenosine polyphosphate catabolic process // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071544 // diphosphoinositol polyphosphate catabolic process // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from direct assay /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // inferred from electronic annotation /// 0008486 // diphosphoinositol-polyphosphate diphosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052840 // inositol diphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052841 // inositol bisdiphosphate tetrakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052842 // inositol diphosphate pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052843 // inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052844 // inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052845 // inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity // inferred from electronic annotation /// 0052846 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity // inferred from electronic annotation /// 0052847 // inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation /// 0052848 // inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity // inferred from electronic annotation" 200096_s_at AI862255 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI862255 /FEA=EST /DB_XREF=gi:5526362 /DB_XREF=est:tb77d10.x1 /CLONE=IMAGE:2060371 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD" AI862255 "ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1" ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation" "0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 200097_s_at AI701949 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI701949 /FEA=EST /DB_XREF=gi:4989849 /DB_XREF=est:tq09c07.x1 /CLONE=IMAGE:2208300 /UG=Hs.129548 heterogeneous nuclear ribonucleoprotein K AI701949 heterogeneous nuclear ribonucleoprotein K HNRNPK 3190 NM_002140 /// NM_031262 /// NM_031263 /// XM_005251960 /// XM_005251961 /// XM_005251963 /// XM_005251964 /// XM_005251965 /// XM_005251966 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0072369 // regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200098_s_at T33068 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:T33068 /FEA=EST /DB_XREF=gi:615166 /DB_XREF=est:EST56576 /UG=Hs.7101 anaphase-promoting complex subunit 5 T33068 anaphase promoting complex subunit 5 ANAPC5 51433 NM_001137559 /// NM_016237 /// XM_005253900 /// XM_006719449 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction 200099_s_at AL356115 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL356115 /DEF=Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands /FEA=CDS_1 /DB_XREF=gi:9795038 /UG=Hs.307132 Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands" AL356115 "ribosomal protein S3A /// small nucleolar RNA, C/D box 73A" RPS3A /// SNORD73A 6189 /// 8944 NM_001006 /// NM_001267699 /// NR_000007 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200593_s_at BC003621 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003621.1 /DEF=Homo sapiens, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A), clone MGC:1992, mRNA, complete cds. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein U(scaffold attachment factor A) /DB_XREF=gi:13177672 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) /FL=gb:BC003367.1 gb:BC003621.1 gb:NM_004501.1" BC003621 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) HNRNPU 3192 NM_004501 /// NM_031844 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200594_x_at NM_004501 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004501.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRPU), mRNA. /FEA=mRNA /GEN=HNRPU /PROD=heterogeneous nuclear ribonucleoprotein U(scaffold attachment factor A) /DB_XREF=gi:4758545 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) /FL=gb:BC003367.1 gb:BC003621.1 gb:NM_004501.1" NM_004501 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) HNRNPU 3192 NM_004501 /// NM_031844 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200595_s_at NM_003750 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003750.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) (EIF3S10), mRNA. /FEA=mRNA /GEN=EIF3S10 /PROD=eukaryotic translation initiation factor 3,subunit 10 (theta, 150170kD) /DB_XREF=gi:4503508 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1" NM_003750 "eukaryotic translation initiation factor 3, subunit A" EIF3A 8661 NM_003750 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200596_s_at BE614908 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE614908 /FEA=EST /DB_XREF=gi:9896507 /DB_XREF=est:601280348F1 /CLONE=IMAGE:3622499 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1" BE614908 "eukaryotic translation initiation factor 3, subunit A" EIF3A 8661 NM_003750 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200597_at AI123320 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI123320 /FEA=EST /DB_XREF=gi:3539086 /DB_XREF=est:qa48a10.x1 /CLONE=IMAGE:1689978 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1" AI123320 "eukaryotic translation initiation factor 3, subunit A" EIF3A 8661 NM_003750 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0001732 // formation of translation initiation complex // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200598_s_at AI582238 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI582238 /FEA=EST /DB_XREF=gi:4568135 /DB_XREF=est:tq65c10.x1 /CLONE=IMAGE:2213682 /UG=Hs.82689 tumor rejection antigen (gp96) 1 /FL=gb:NM_003299.1 AI582238 "heat shock protein 90kDa beta (Grp94), member 1 /// microRNA 3652" HSP90B1 /// MIR3652 7184 /// 100500842 NM_003299 /// NR_037425 0001666 // response to hypoxia // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031247 // actin rod assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement /// 0071318 // cellular response to ATP // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200599_s_at NM_003299 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003299.1 /DEF=Homo sapiens tumor rejection antigen (gp96) 1 (TRA1), mRNA. /FEA=mRNA /GEN=TRA1 /PROD=tumor rejection antigen (gp96) 1 /DB_XREF=gi:4507676 /UG=Hs.82689 tumor rejection antigen (gp96) 1 /FL=gb:NM_003299.1" NM_003299 "heat shock protein 90kDa beta (Grp94), member 1 /// microRNA 3652" HSP90B1 /// MIR3652 7184 /// 100500842 NM_003299 /// NR_037425 0001666 // response to hypoxia // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031247 // actin rod assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement /// 0071318 // cellular response to ATP // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from direct assay /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200600_at NM_002444 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002444.1 /DEF=Homo sapiens moesin (MSN), mRNA. /FEA=mRNA /GEN=MSN /PROD=moesin /DB_XREF=gi:4505256 /UG=Hs.170328 moesin /FL=gb:M69066.1 gb:NM_002444.1" NM_002444 moesin MSN 4478 NM_002444 /// XM_005262269 0006928 // cellular component movement // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from expression pattern /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0050900 // leukocyte migration // inferred from expression pattern /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 2000401 // regulation of lymphocyte migration // inferred from mutant phenotype 0001931 // uropod // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 200601_at U48734 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U48734.1 /DEF=Human non-muscle alpha-actinin mRNA, complete cds. /FEA=mRNA /PROD=alpha actinin /DB_XREF=gi:3157975 /UG=Hs.182485 actinin, alpha 4 /FL=gb:NM_004924.2 gb:BC005033.1 gb:D89980.1 gb:U48734.1" U48734 "actinin, alpha 4" ACTN4 81 NM_004924 /// XM_005259281 /// XM_005259282 /// XM_006723406 0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032417 // positive regulation of sodium:proton antiporter activity // non-traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048549 // positive regulation of pinocytosis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from electronic annotation /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051272 // positive regulation of cellular component movement // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001882 // nucleoside binding // inferred from direct assay /// 0003779 // actin binding // traceable author statement /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 200602_at NM_000484 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000484.1 /DEF=Homo sapiens amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) (APP), mRNA. /FEA=mRNA /GEN=APP /PROD=amyloid beta (A4) precursor protein (proteasenexin-II, Alzheimer disease) /DB_XREF=gi:4502166 /UG=Hs.177486 amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) /FL=gb:NM_000484.1" NM_000484 amyloid beta (A4) precursor protein APP 351 NM_000484 /// NM_001136016 /// NM_001136129 /// NM_001136130 /// NM_001136131 /// NM_001204301 /// NM_001204302 /// NM_001204303 /// NM_201413 /// NM_201414 "0000085 // mitotic G2 phase // inferred from sequence or structural similarity /// 0001967 // suckling behavior // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006878 // cellular copper ion homeostasis // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007617 // mating behavior // inferred from sequence or structural similarity /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008088 // axon cargo transport // inferred from sequence or structural similarity /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0016199 // axon midline choice point recognition // inferred from sequence or structural similarity /// 0016322 // neuron remodeling // inferred from sequence or structural similarity /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048669 // collateral sprouting in absence of injury // inferred from sequence or structural similarity /// 0050803 // regulation of synapse structure and activity // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051124 // synaptic growth at neuromuscular junction // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from mutant phenotype /// 0051563 // smooth endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030424 // axon // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from direct assay /// 0043198 // dendritic shaft // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from sequence or structural similarity /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from physical interaction /// 0070851 // growth factor receptor binding // inferred from electronic annotation 200603_at AL050038 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL050038.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566J0124 (from clone DKFZp566J0124). /FEA=mRNA /DB_XREF=gi:4884279 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1" AL050038 "protein kinase, cAMP-dependent, regulatory, type I, alpha" PRKAR1A 5573 NM_001276289 /// NM_001276290 /// NM_001278433 /// NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 200604_s_at M18468 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M18468.1 /DEF=Human cAMP-dependent protein kinase regulatory subunit type I (PRKAR1A) mRNA, complete cds. /FEA=mRNA /GEN=PRKAR1A /PROD=cAMP-dependent protein kinase regulatory subunittype 1 /DB_XREF=gi:1526988 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1" M18468 "protein kinase, cAMP-dependent, regulatory, type I, alpha" PRKAR1A 5573 NM_001276289 /// NM_001276290 /// NM_001278433 /// NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 200605_s_at NM_002734 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002734.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), mRNA. /FEA=mRNA /GEN=PRKAR1A /PROD=protein kinase, cAMP-dependent, regulatory, typeI, alpha /DB_XREF=gi:4506062 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1" NM_002734 "protein kinase, cAMP-dependent, regulatory, type I, alpha" PRKAR1A 5573 NM_001276289 /// NM_001276290 /// NM_001278433 /// NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045835 // negative regulation of meiosis // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 200606_at NM_004415 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004415.1 /DEF=Homo sapiens desmoplakin (DPI, DPII) (DSP), mRNA. /FEA=mRNA /GEN=DSP /PROD=desmoplakin (DPI, DPII) /DB_XREF=gi:4758199 /UG=Hs.74316 desmoplakin (DPI, DPII) /FL=gb:M77830.3 gb:NM_004415.1" NM_004415 desmoplakin DSP 1832 NM_001008844 /// NM_004415 0002934 // desmosome organization // inferred from sequence or structural similarity /// 0003223 // ventricular compact myocardium morphogenesis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from sequence or structural similarity /// 0071896 // protein localization to adherens junction // inferred from sequence or structural similarity /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype 0001533 // cornified envelope // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005080 // protein kinase C binding // inferred from physical interaction /// 0005198 // structural molecule activity // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from physical interaction" 200607_s_at BG289967 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG289967 /FEA=EST /DB_XREF=gi:13046289 /DB_XREF=est:602381386F1 /CLONE=IMAGE:4499085 /UG=Hs.81848 RAD21 (S. pombe) homolog /FL=gb:D38551.1 gb:NM_006265.1 BG289967 RAD21 homolog (S. pombe) RAD21 5885 NM_006265 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0071168 // protein localization to chromatin // inferred from mutant phenotype "0000228 // nuclear chromosome // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation" 0005515 // protein binding // inferred from physical interaction 200608_s_at NM_006265 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006265.1 /DEF=Homo sapiens RAD21 (S. pombe) homolog (RAD21), mRNA. /FEA=mRNA /GEN=RAD21 /PROD=RAD21 (S. pombe) homolog /DB_XREF=gi:5453993 /UG=Hs.81848 RAD21 (S. pombe) homolog /FL=gb:D38551.1 gb:NM_006265.1" NM_006265 RAD21 homolog (S. pombe) RAD21 5885 NM_006265 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0071168 // protein localization to chromatin // inferred from mutant phenotype "0000228 // nuclear chromosome // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0034991 // nuclear meiotic cohesin complex // inferred from electronic annotation" 0005515 // protein binding // inferred from physical interaction 200609_s_at NM_017491 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017491.1 /DEF=Homo sapiens WD repeat domain 1 (WDR1), transcript variant 1, mRNA. /FEA=mRNA /GEN=WDR1 /PROD=WD repeat-containing protein 1, isoform 1 /DB_XREF=gi:9257256 /UG=Hs.85100 WD repeat domain 1 /FL=gb:BC000201.1 gb:BC002489.1 gb:AF020056.1 gb:AB010427.2 gb:NM_017491.1" NM_017491 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 /// XM_006713988 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0030168 // platelet activation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200610_s_at NM_005381 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005381.1 /DEF=Homo sapiens nucleolin (NCL), mRNA. /FEA=mRNA /GEN=NCL /PROD=nucleolin /DB_XREF=gi:4885510 /UG=Hs.79110 nucleolin /FL=gb:NM_005381.1" NM_005381 nucleolin NCL 4691 NM_005381 0001525 // angiogenesis // inferred from direct assay /// 1901838 // positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200611_s_at AB010427 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB010427.2 /DEF=Homo sapiens mRNA for NORI-1, complete cds. /FEA=mRNA /PROD=NORI-1 /DB_XREF=gi:5103672 /UG=Hs.85100 WD repeat domain 1 /FL=gb:BC000201.1 gb:BC002489.1 gb:AF020056.1 gb:AB010427.2 gb:NM_017491.1" AB010427 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 /// XM_006713988 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0030168 // platelet activation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200612_s_at NM_001282 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001282.1 /DEF=Homo sapiens adaptor-related protein complex 2, beta 1 subunit (AP2B1), mRNA. /FEA=mRNA /GEN=AP2B1 /PROD=adaptor-related protein complex 2, beta 1subunit /DB_XREF=gi:4557468 /UG=Hs.74626 adaptor-related protein complex 2, beta 1 subunit /FL=gb:M34175.1 gb:NM_001282.1" NM_001282 "adaptor-related protein complex 2, beta 1 subunit" AP2B1 163 NM_001030006 /// NM_001282 /// XM_005257937 /// XM_005257938 /// XM_005257941 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 200613_at NM_004068 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004068.1 /DEF=Homo sapiens adaptor-related protein complex 2, mu 1 subunit (AP2M1), mRNA. /FEA=mRNA /GEN=AP2M1 /PROD=adaptor-related protein complex 2, mu 1 subunit /DB_XREF=gi:4757993 /UG=Hs.152936 adaptor-related protein complex 2, mu 1 subunit /FL=gb:U36188.1 gb:BC004996.1 gb:D63475.1 gb:NM_004068.1" NM_004068 "adaptor-related protein complex 2, mu 1 subunit" AP2M1 1173 NM_001025205 /// NM_004068 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 200614_at NM_004859 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004859.1 /DEF=Homo sapiens clathrin, heavy polypeptide (Hc) (CLTC), mRNA. /FEA=mRNA /GEN=CLTC /PROD=clathrin heavy chain /DB_XREF=gi:4758011 /UG=Hs.178710 clathrin, heavy polypeptide (Hc) /FL=gb:D21260.1 gb:NM_004859.1" NM_004859 "clathrin, heavy chain (Hc)" CLTC 1213 NM_001288653 /// NM_004859 /// XM_005257012 0001649 // osteoblast differentiation // inferred from direct assay /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0033572 // transferrin transport // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031523 // Myb complex // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005198 // structural molecule activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0032051 // clathrin light chain binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200615_s_at AL567295 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL567295 /FEA=EST /DB_XREF=gi:12920509 /DB_XREF=est:AL567295 /CLONE=CS0DF027YO06 (3 prime) /UG=Hs.74626 adaptor-related protein complex 2, beta 1 subunit /FL=gb:M34175.1 gb:NM_001282.1" AL567295 "adaptor-related protein complex 2, beta 1 subunit" AP2B1 163 NM_001030006 /// NM_001282 /// XM_005257937 /// XM_005257938 /// XM_005257941 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 200616_s_at BC000371 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000371.1 /DEF=Homo sapiens, KIAA0152 gene product, clone MGC:8341, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0152 gene product /DB_XREF=gi:12653206 /UG=Hs.181418 KIAA0152 gene product /FL=gb:BC000371.1 gb:D63486.1 gb:NM_014730.1" BC000371 malectin MLEC 9761 NM_014730 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019899 // enzyme binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from sequence or structural similarity 200617_at NM_014730 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014730.1 /DEF=Homo sapiens KIAA0152 gene product (KIAA0152), mRNA. /FEA=mRNA /GEN=KIAA0152 /PROD=KIAA0152 gene product /DB_XREF=gi:7661947 /UG=Hs.181418 KIAA0152 gene product /FL=gb:BC000371.1 gb:D63486.1 gb:NM_014730.1" NM_014730 malectin MLEC 9761 NM_014730 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0019899 // enzyme binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from sequence or structural similarity 200618_at NM_006148 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006148.1 /DEF=Homo sapiens LIM and SH3 protein 1 (LASP1), mRNA. /FEA=mRNA /GEN=LASP1 /PROD=LIM and SH3 protein 1 /DB_XREF=gi:5453709 /UG=Hs.75080 LIM and SH3 protein 1 /FL=gb:NM_006148.1" NM_006148 LIM and SH3 protein 1 LASP1 3927 NM_001271608 /// NM_006148 /// NR_073384 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 200619_at NM_006842 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006842.1 /DEF=Homo sapiens splicing factor 3b, subunit 2, 145kD (SF3B2), mRNA. /FEA=mRNA /GEN=SF3B2 /PROD=splicing factor 3b, subunit 2, 145kD /DB_XREF=gi:5803154 /UG=Hs.75916 splicing factor 3b, subunit 2, 145kD /FL=gb:U41371.1 gb:NM_006842.1" NM_006842 "splicing factor 3b, subunit 2, 145kDa" SF3B2 10992 NM_006842 /// XM_005273726 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200620_at NM_004872 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004872.1 /DEF=Homo sapiens chromosome 1 open reading frame 8 (C1ORF8), mRNA. /FEA=mRNA /GEN=C1ORF8 /PROD=chromosome 1 open reading frame 8 /DB_XREF=gi:4758571 /UG=Hs.11441 chromosome 1 open reading frame 8 /FL=gb:BC003106.1 gb:AF290615.1 gb:AF047439.1 gb:NM_004872.1" NM_004872 transmembrane protein 59 TMEM59 9528 NM_004872 /// XM_005271350 /// XM_005271351 /// XM_006711051 0006508 // proteolysis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0010955 // negative regulation of protein processing // inferred from direct assay /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090285 // negative regulation of protein glycosylation in Golgi // inferred from direct assay 0000137 // Golgi cis cisterna // inferred from direct assay /// 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005797 // Golgi medial cisterna // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200621_at NM_004078 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004078.1 /DEF=Homo sapiens cysteine and glycine-rich protein 1 (CSRP1), mRNA. /FEA=mRNA /GEN=CSRP1 /PROD=cysteine and glycine-rich protein 1 /DB_XREF=gi:4758085 /UG=Hs.108080 cysteine and glycine-rich protein 1 /FL=gb:M33146.1 gb:NM_004078.1" NM_004078 cysteine and glycine-rich protein 1 CSRP1 1465 NM_001144773 /// NM_001193570 /// NM_001193571 /// NM_001193572 /// NM_004078 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200622_x_at AV685208 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AV685208 /FEA=EST /DB_XREF=gi:10287071 /DB_XREF=est:AV685208 /CLONE=GKCCXA06 /UG=Hs.141011 calmodulin 3 (phosphorylase kinase, delta) /FL=gb:BC005137.1 gb:J04046.1 gb:NM_005184.1" AV685208 "calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta)" CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 "0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator" 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200623_s_at NM_005184 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005184.1 /DEF=Homo sapiens calmodulin 3 (phosphorylase kinase, delta) (CALM3), mRNA. /FEA=mRNA /GEN=CALM3 /PROD=calmodulin 3 (phosphorylase kinase, delta) /DB_XREF=gi:4885108 /UG=Hs.141011 calmodulin 3 (phosphorylase kinase, delta) /FL=gb:BC005137.1 gb:J04046.1 gb:NM_005184.1" NM_005184 "calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta)" CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 "0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator" 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200624_s_at AA577695 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA577695 /FEA=EST /DB_XREF=gi:2355879 /DB_XREF=est:nn22h02.s1 /CLONE=IMAGE:1084659 /UG=Hs.78825 matrin 3 /FL=gb:NM_018834.1 gb:AB018266.1 AA577695 matrin 3 /// small nucleolar RNA host gene 4 (non-protein coding) MATR3 /// SNHG4 9782 /// 724102 NM_001194954 /// NM_001194955 /// NM_001194956 /// NM_001282278 /// NM_018834 /// NM_199189 /// NR_003141 /// NR_036536 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200625_s_at NM_006367 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006367.2 /DEF=Homo sapiens adenylyl cyclase-associated protein (CAP), mRNA. /FEA=mRNA /GEN=CAP /PROD=adenylyl cyclase-associated protein /DB_XREF=gi:10938021 /UG=Hs.104125 adenylyl cyclase-associated protein /FL=gb:NM_006367.2 gb:L12168.1 gb:M98474.1" NM_006367 "CAP, adenylate cyclase-associated protein 1 (yeast)" CAP1 10487 NM_001105530 /// NM_006367 /// XM_005270367 /// XM_005270368 /// XM_006710294 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200626_s_at NM_018834 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018834.1 /DEF=Homo sapiens matrin 3 (MATR3), mRNA. /FEA=mRNA /GEN=MATR3 /PROD=matrin 3 /DB_XREF=gi:10047081 /UG=Hs.78825 matrin 3 /FL=gb:NM_018834.1 gb:AB018266.1" NM_018834 matrin 3 /// small nucleolar RNA host gene 4 (non-protein coding) MATR3 /// SNHG4 9782 /// 724102 NM_001194954 /// NM_001194955 /// NM_001194956 /// NM_001282278 /// NM_018834 /// NM_199189 /// NR_003141 /// NR_036536 0005634 // nucleus // inferred from direct assay /// 0005637 // nuclear inner membrane // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200627_at BC003005 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003005.1 /DEF=Homo sapiens, unactive progesterone receptor, 23 kD, clone MGC:4004, mRNA, complete cds. /FEA=mRNA /PROD=unactive progesterone receptor, 23 kD /DB_XREF=gi:12804292 /UG=Hs.278270 unactive progesterone receptor, 23 kD /FL=gb:BC003005.1 gb:L24804.1 gb:NM_006601.1" BC003005 prostaglandin E synthase 3 (cytosolic) PTGES3 10728 NM_001282601 /// NM_001282602 /// NM_001282603 /// NM_001282604 /// NM_001282605 /// NM_006601 /// NR_104219 /// XM_005268576 /// XM_006719199 /// XR_245889 /// XR_429072 0000723 // telomere maintenance // traceable author statement /// 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0006278 // RNA-dependent DNA replication // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay "0000781 // chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0003720 // telomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0050220 // prostaglandin-E synthase activity // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 200628_s_at M61715 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M61715.1 /DEF=Human tryptophanyl-tRNA synthetase (WRS) mRNA, complete cds. /FEA=mRNA /GEN=WARS /PROD=transfer RNA-Trp synthetase /DB_XREF=gi:340367 /UG=Hs.82030 tryptophanyl-tRNA synthetase /FL=gb:M77804.1 gb:M61715.1 gb:NM_004184.2" M61715 tryptophanyl-tRNA synthetase WARS 7453 NM_004184 /// NM_173701 /// NM_213645 /// NM_213646 /// XM_005268044 /// XM_006720248 /// XM_006720249 0001525 // angiogenesis // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006436 // tryptophanyl-tRNA aminoacylation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004830 // tryptophan-tRNA ligase activity // non-traceable author statement /// 0004830 // tryptophan-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200629_at NM_004184 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004184.2 /DEF=Homo sapiens tryptophanyl-tRNA synthetase (WARS), mRNA. /FEA=mRNA /GEN=WARS /PROD=tryptophanyl-tRNA synthetase /DB_XREF=gi:7710155 /UG=Hs.82030 tryptophanyl-tRNA synthetase /FL=gb:M77804.1 gb:M61715.1 gb:NM_004184.2" NM_004184 tryptophanyl-tRNA synthetase WARS 7453 NM_004184 /// NM_173701 /// NM_213645 /// NM_213646 /// XM_005268044 /// XM_006720248 /// XM_006720249 0001525 // angiogenesis // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006436 // tryptophanyl-tRNA aminoacylation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004830 // tryptophan-tRNA ligase activity // non-traceable author statement /// 0004830 // tryptophan-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200630_x_at AV702810 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV702810 /FEA=EST /DB_XREF=gi:10719140 /DB_XREF=est:AV702810 /CLONE=ADBDGH01 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) /FL=gb:U51924.1 gb:M93651.1 gb:NM_003011.1 AV702810 SET nuclear proto-oncogene /// SET-like protein SET /// SETSIP 6418 /// 646817 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_001287737 /// NM_003011 "0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 200631_s_at NM_003011 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003011.1 /DEF=Homo sapiens SET translocation (myeloid leukemia-associated) (SET), mRNA. /FEA=mRNA /GEN=SET /PROD=SET translocation (myeloid leukemia-associated) /DB_XREF=gi:4506890 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) /FL=gb:U51924.1 gb:M93651.1 gb:NM_003011.1" NM_003011 SET nuclear proto-oncogene /// SET-like protein SET /// SETSIP 6418 /// 646817 NM_001122821 /// NM_001248000 /// NM_001248001 /// NM_001287737 /// NM_003011 "0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0045446 // endothelial cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050790 // regulation of catalytic activity // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 200632_s_at NM_006096 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006096.1 /DEF=Homo sapiens N-myc downstream regulated (NDRG1), mRNA. /FEA=mRNA /GEN=NDRG1 /PROD=N-myc downstream regulated /DB_XREF=gi:5174656 /UG=Hs.75789 N-myc downstream regulated /FL=gb:BC003175.1 gb:D87953.1 gb:AF004162.1 gb:NM_006096.1" NM_006096 N-myc downstream regulated 1 NDRG1 10397 NM_001135242 /// NM_001258432 /// NM_001258433 /// NM_006096 "0008219 // cell death // inferred from electronic annotation /// 0010038 // response to metal ion // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from expression pattern /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0045576 // mast cell activation // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090232 // positive regulation of spindle checkpoint // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from direct assay /// 0043015 // gamma-tubulin binding // inferred from direct assay /// 0045296 // cadherin binding // inferred from direct assay 200633_at NM_018955 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018955.1 /DEF=Homo sapiens ubiquitin B (UBB), mRNA. /FEA=mRNA /GEN=UBB /PROD=ubiquitin B /DB_XREF=gi:11024713 /UG=Hs.183842 ubiquitin B /FL=gb:NM_018955.1 gb:BC000379.1" NM_018955 ubiquitin B UBB 7314 NM_001281716 /// NM_001281717 /// NM_001281718 /// NM_001281719 /// NM_001281720 /// NM_018955 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010992 // ubiquitin homeostasis // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0021888 // hypothalamus gonadotrophin-releasing hormone neuron development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060613 // fat pad development // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0072520 // seminiferous tubule development // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement /// 0097009 // energy homeostasis // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 200634_at NM_005022 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005022.1 /DEF=Homo sapiens profilin 1 (PFN1), mRNA. /FEA=mRNA /GEN=PFN1 /PROD=profilin 1 /DB_XREF=gi:4826897 /UG=Hs.75721 profilin 1 /FL=gb:BC002475.1 gb:J03191.1 gb:NM_005022.1" NM_005022 profilin 1 PFN1 5216 NM_005022 0001843 // neural tube closure // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030837 // negative regulation of actin filament polymerization // inferred from direct assay /// 0030838 // positive regulation of actin filament polymerization // inferred from genetic interaction /// 0032232 // negative regulation of actin filament bundle assembly // inferred from mutant phenotype /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // inferred from electronic annotation /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 1900029 // positive regulation of ruffle assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay "0000774 // adenyl-nucleotide exchange factor activity // inferred from direct assay /// 0003779 // actin binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction" 200635_s_at AU145351 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU145351 /FEA=EST /DB_XREF=gi:11006872 /DB_XREF=est:AU145351 /CLONE=HEMBA1004591 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1" AU145351 "protein tyrosine phosphatase, receptor type, F" PTPRF 5792 NM_002840 /// NM_130440 /// XM_005271079 /// XM_005271080 /// XM_005271081 /// XM_005271082 /// XM_006710795 /// XM_006710796 /// XM_006710797 /// XM_006710798 /// XM_006710799 /// XM_006710800 /// XM_006710801 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 1900121 // negative regulation of receptor binding // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200636_s_at NM_002840 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002840.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, F (PTPRF), mRNA. /FEA=mRNA /GEN=PTPRF /PROD=protein tyrosine phosphatase, receptor type, fpolypeptide /DB_XREF=gi:4506310 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1" NM_002840 "protein tyrosine phosphatase, receptor type, F" PTPRF 5792 NM_002840 /// NM_130440 /// XM_005271079 /// XM_005271080 /// XM_005271081 /// XM_005271082 /// XM_006710795 /// XM_006710796 /// XM_006710797 /// XM_006710798 /// XM_006710799 /// XM_006710800 /// XM_006710801 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 1900121 // negative regulation of receptor binding // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200637_s_at AI762627 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI762627 /FEA=EST /DB_XREF=gi:5178294 /DB_XREF=est:wi56g01.x1 /CLONE=IMAGE:2394288 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1" AI762627 "protein tyrosine phosphatase, receptor type, F" PTPRF 5792 NM_002840 /// NM_130440 /// XM_005271079 /// XM_005271080 /// XM_005271081 /// XM_005271082 /// XM_006710795 /// XM_006710796 /// XM_006710797 /// XM_006710798 /// XM_006710799 /// XM_006710800 /// XM_006710801 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 1900121 // negative regulation of receptor binding // inferred from mutant phenotype 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from mutant phenotype /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200638_s_at BC003623 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003623.1 /DEF=Homo sapiens, tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide, clone MGC:2153, mRNA, complete cds. /FEA=mRNA /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:13177678 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1" BC003623 "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta" YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200639_s_at NM_003406 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003406.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), mRNA. /FEA=mRNA /GEN=YWHAZ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:4507952 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1" NM_003406 "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta" YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200640_at NM_003406 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003406.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), mRNA. /FEA=mRNA /GEN=YWHAZ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:4507952 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1" NM_003406 "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta" YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200641_s_at U28964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U28964.1 /DEF=Homo sapiens 14-3-3 protein mRNA, complete cds. /FEA=mRNA /PROD=14-3-3 protein /DB_XREF=gi:899458 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1" U28964 "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta" YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 /// XM_005251060 /// XM_005251061 /// XM_005251062 /// XM_005251063 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200642_at NM_000454 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000454.1 /DEF=Homo sapiens superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1), mRNA. /FEA=mRNA /GEN=SOD1 /PROD=superoxide dismutase 1, soluble (amyotrophiclateral sclerosis 1 (adult)) /DB_XREF=gi:4507148 /UG=Hs.75428 superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) /FL=gb:BC001034.1 gb:K00065.1 gb:NM_000454.1" NM_000454 "superoxide dismutase 1, soluble" SOD1 6647 NM_000454 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000303 // response to superoxide // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0001890 // placenta development // non-traceable author statement /// 0001895 // retina homeostasis // inferred from sequence or structural similarity /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from sequence or structural similarity /// 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // inferred from sequence or structural similarity /// 0006879 // cellular iron ion homeostasis // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007566 // embryo implantation // inferred from sequence or structural similarity /// 0007566 // embryo implantation // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008219 // cell death // inferred from electronic annotation /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0010033 // response to organic substance // inferred from direct assay /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0019430 // removal of superoxide radicals // not recorded /// 0019430 // removal of superoxide radicals // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032287 // peripheral nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0033081 // regulation of T cell differentiation in thymus // non-traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from sequence or structural similarity /// 0042554 // superoxide anion generation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred by curator /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0046620 // regulation of organ growth // non-traceable author statement /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity /// 0048538 // thymus development // non-traceable author statement /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0050665 // hydrogen peroxide biosynthetic process // inferred from direct assay /// 0050665 // hydrogen peroxide biosynthetic process // inferred from sequence or structural similarity /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060047 // heart contraction // inferred from direct assay /// 0060052 // neurofilament cytoskeleton organization // inferred from sequence or structural similarity /// 0060087 // relaxation of vascular smooth muscle // inferred from sequence or structural similarity /// 0060088 // auditory receptor cell stereocilium organization // inferred from sequence or structural similarity /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 1902177 // positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0032839 // dendrite cytoplasm // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004784 // superoxide dismutase activity // not recorded /// 0004784 // superoxide dismutase activity // inferred from direct assay /// 0004784 // superoxide dismutase activity // traceable author statement /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction 200643_at NM_005336 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005336.1 /DEF=Homo sapiens high density lipoprotein binding protein (vigilin) (HDLBP), mRNA. /FEA=mRNA /GEN=HDLBP /PROD=high density lipoprotein binding protein /DB_XREF=gi:4885408 /UG=Hs.177516 high density lipoprotein binding protein (vigilin) /FL=gb:BC001179.1 gb:M64098.1 gb:NM_005336.1" NM_005336 high density lipoprotein binding protein HDLBP 3069 NM_001243900 /// NM_005336 /// NM_203346 /// XM_005247000 /// XM_005247001 /// XM_005247002 /// XM_005247003 /// XM_006712475 /// XM_006712476 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0034364 // high-density lipoprotein particle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200644_at NM_023009 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_023009.1 /DEF=Homo sapiens macrophage myristoylated alanine-rich C kinase substrate (MACMARCKS), mRNA. /FEA=mRNA /GEN=MACMARCKS /PROD=macrophage myristoylated alanine-rich C kinasesubstrate /DB_XREF=gi:13491173 /UG=Hs.75061 macrophage myristoylated alanine-rich C kinase substrate /FL=gb:NM_023009.1" NM_023009 MARCKS-like 1 MARCKSL1 65108 NM_023009 /// NR_052852 0008284 // positive regulation of cell proliferation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 200645_at NM_007278 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007278.1 /DEF=Homo sapiens GABA(A) receptor-associated protein (GABARAP), mRNA. /FEA=mRNA /GEN=GABARAP /PROD=GABA(A) receptor-associated protein /DB_XREF=gi:6005763 /UG=Hs.7719 GABA(A) receptor-associated protein /FL=gb:AB030711.1 gb:AF044671.1 gb:AF067171.1 gb:AF161586.1 gb:NM_007278.1 gb:AF183425.1" NM_007278 GABA(A) receptor-associated protein GABARAP 11337 NM_007278 0000045 // autophagic vacuole assembly // not recorded /// 0000226 // microtubule cytoskeleton organization // not recorded /// 0000422 // mitochondrion degradation // not recorded /// 0006605 // protein targeting // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0032258 // CVT pathway // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0044805 // late nucleophagy // not recorded /// 0071211 // protein targeting to vacuole involved in autophagy // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // not recorded /// 0008429 // phosphatidylethanolamine binding // not recorded /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from physical interaction 200646_s_at NM_006184 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006184.1 /DEF=Homo sapiens nucleobindin 1 (NUCB1), mRNA. /FEA=mRNA /GEN=NUCB1 /PROD=nucleobindin 1 /DB_XREF=gi:5453817 /UG=Hs.172609 nucleobindin 1 /FL=gb:BC002356.1 gb:M96824.1 gb:NM_006184.1" NM_006184 nucleobindin 1 NUCB1 4924 NM_006184 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200647_x_at NM_003752 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003752.2 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 8 (110kD) (EIF3S8), mRNA. /FEA=mRNA /GEN=EIF3S8 /PROD=eukaryotic translation initiation factor 3,subunit 8 (110kD) /DB_XREF=gi:5579457 /UG=Hs.4835 eukaryotic translation initiation factor 3, subunit 8 (110kD) /FL=gb:NM_003752.2" NM_003752 "eukaryotic translation initiation factor 3, subunit C /// eukaryotic translation initiation factor 3, subunit C-like" EIF3C /// EIF3CL 8663 /// 728689 NM_001037808 /// NM_001099661 /// NM_001199142 /// NM_001267574 /// NM_001286478 /// NM_003752 /// XM_005255535 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from electronic annotation /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200648_s_at NM_002065 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002065.1 /DEF=Homo sapiens glutamate-ammonia ligase (glutamine synthase) (GLUL), mRNA. /FEA=mRNA /GEN=GLUL /PROD=glutamate-ammonia ligase (glutamine synthase) /DB_XREF=gi:4504026 /UG=Hs.170171 glutamate-ammonia ligase (glutamine synthase) /FL=gb:NM_002065.1" NM_002065 glutamate-ammonia ligase GLUL 2752 NM_001033044 /// NM_001033056 /// NM_002065 /// XM_006711278 "0001504 // neurotransmitter uptake // traceable author statement /// 0006536 // glutamate metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // traceable author statement /// 0006542 // glutamine biosynthetic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity // inferred from electronic annotation /// 0004356 // glutamate-ammonia ligase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045503 // dynein light chain binding // inferred from electronic annotation 200649_at BC002356 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002356.1 /DEF=Homo sapiens, nucleobindin 1, clone MGC:8479, mRNA, complete cds. /FEA=mRNA /PROD=nucleobindin 1 /DB_XREF=gi:12803104 /UG=Hs.172609 nucleobindin 1 /FL=gb:BC002356.1 gb:M96824.1 gb:NM_006184.1" BC002356 nucleobindin 1 NUCB1 4924 NM_006184 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200650_s_at NM_005566 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005566.1 /DEF=Homo sapiens lactate dehydrogenase A (LDHA), mRNA. /FEA=mRNA /GEN=LDHA /PROD=LDHA /DB_XREF=gi:5031856 /UG=Hs.2795 lactate dehydrogenase A /FL=gb:BC001829.1 gb:NM_005566.1" NM_005566 lactate dehydrogenase A LDHA 3939 NM_001135239 /// NM_001165414 /// NM_001165415 /// NM_001165416 /// NM_005566 /// NR_028500 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // non-traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation" 200651_at NM_006098 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006098.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 (GNB2L1), mRNA. /FEA=mRNA /GEN=GNB2L1 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 2-like 1 /DB_XREF=gi:5174446 /UG=Hs.5662 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 /FL=gb:BC000214.1 gb:BC000366.1 gb:BC000672.1 gb:M24194.1 gb:NM_006098.1" NM_006098 "guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 /// small nucleolar RNA, C/D box 95 /// small nucleolar RNA, C/D box 96A" GNB2L1 /// SNORD95 /// SNORD96A 10399 /// 619570 /// 619571 NM_006098 /// NR_002591 /// NR_002592 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030822 // positive regulation of cAMP catabolic process // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from sequence or structural similarity /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from mutant phenotype /// 0051302 // regulation of cell division // inferred from sequence or structural similarity /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051901 // positive regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay /// 0090003 // regulation of establishment of protein localization to plasma membrane // inferred from electronic annotation /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from genetic interaction /// 2000114 // regulation of establishment of cell polarity // inferred from sequence or structural similarity /// 2000543 // positive regulation of gastrulation // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0001891 // phagocytic cup // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005829 // cytosol // inferred from mutant phenotype /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from direct assay /// 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008200 // ion channel inhibitor activity // inferred from sequence or structural similarity /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030292 // protein tyrosine kinase inhibitor activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from direct assay /// 0032947 // protein complex scaffold // traceable author statement /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200652_at NM_003145 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003145.2 /DEF=Homo sapiens signal sequence receptor, beta (translocon-associated protein beta) (SSR2), mRNA. /FEA=mRNA /GEN=SSR2 /PROD=signal sequence receptor, beta precursor /DB_XREF=gi:6552341 /UG=Hs.74564 signal sequence receptor, beta (translocon-associated protein beta) /FL=gb:D37991.1 gb:BC000341.1 gb:NM_003145.2" NM_003145 "signal sequence receptor, beta (translocon-associated protein beta)" SSR2 6746 NM_003145 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200653_s_at M27319 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M27319.1 /DEF=Human calmodulin mRNA, complete cds. /FEA=mRNA /PROD=calmodulin /DB_XREF=gi:179809 /UG=Hs.177656 calmodulin 1 (phosphorylase kinase, delta) /FL=gb:M27319.1 gb:NM_006888.1" M27319 "calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta)" CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 "0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator" 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200654_at J02783 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J02783.1 /DEF=Human thyroid hormone binding protein (p55) mRNA, complete cds. /FEA=mRNA /GEN=P4HB /DB_XREF=gi:339646 /UG=Hs.75655 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) /FL=gb:J02783.1 gb:NM_000918.1" J02783 "prolyl 4-hydroxylase, beta polypeptide" P4HB 5034 NM_000918 0006457 // protein folding // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016222 // procollagen-proline 4-dioxygenase complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0004656 // procollagen-proline 4-dioxygenase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 200655_s_at NM_006888 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006888.1 /DEF=Homo sapiens calmodulin 1 (phosphorylase kinase, delta) (CALM1), mRNA. /FEA=mRNA /GEN=CALM1 /PROD=calmodulin 1 (phosphorylase kinase, delta) /DB_XREF=gi:5901911 /UG=Hs.177656 calmodulin 1 (phosphorylase kinase, delta) /FL=gb:M27319.1 gb:NM_006888.1" NM_006888 "calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta)" CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001166106 /// NM_001743 /// NM_005184 /// NM_006888 /// XM_006720258 "0001975 // response to amphetamine // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0005513 // detection of calcium ion // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030801 // positive regulation of cyclic nucleotide metabolic process // inferred from direct assay /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051343 // positive regulation of cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from electronic annotation /// 1901844 // regulation of cell communication by electrical coupling involved in cardiac conduction // inferred by curator" 0000922 // spindle pole // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0030017 // sarcomere // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0034704 // calcium channel complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0031800 // type 3 metabotropic glutamate receptor binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation /// 0072542 // protein phosphatase activator activity // inferred from direct assay 200656_s_at NM_000918 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000918.1 /DEF=Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) (P4HB), mRNA. /FEA=mRNA /GEN=P4HB /PROD=procollagen-proline, 2-oxoglutarate4-dioxygenase (proline 4-hydroxylase), beta polypeptide(protein disulfide isomerase; thyroid hormone bindingprotein p55) /DB_XREF=gi:4505566 /UG=Hs.75655 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) /FL=gb:J02783.1 gb:NM_000918.1" NM_000918 "prolyl 4-hydroxylase, beta polypeptide" P4HB 5034 NM_000918 0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 1902175 // regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016222 // procollagen-proline 4-dioxygenase complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // not recorded /// 0004656 // procollagen-proline 4-dioxygenase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 200657_at NM_001152 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001152.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 (SLC25A5), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC25A5 /PROD=solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 5 /DB_XREF=gi:4502098 /UG=Hs.79172 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 /FL=gb:J02683.1 gb:NM_001152.1" NM_001152 "solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5" SLC25A5 292 NM_001152 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0015853 // adenine transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071817 // MMXD complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015207 // adenine transmembrane transporter activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200658_s_at AL560017 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL560017 /FEA=EST /DB_XREF=gi:12906073 /DB_XREF=est:AL560017 /CLONE=CS0DG004YD08 (5 prime) /UG=Hs.75323 prohibitin /FL=gb:NM_002634.2 AL560017 prohibitin PHB 5245 NM_001281496 /// NM_001281497 /// NM_001281715 /// NM_002634 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016575 // histone deacetylation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0071354 // cellular response to interleukin-6 // inferred from direct assay /// 0071897 // DNA biosynthetic process // inferred from electronic annotation /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 200659_s_at NM_002634 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002634.2 /DEF=Homo sapiens prohibitin (PHB), mRNA. /FEA=mRNA /GEN=PHB /PROD=prohibitin /DB_XREF=gi:6031190 /UG=Hs.75323 prohibitin /FL=gb:NM_002634.2" NM_002634 prohibitin PHB 5245 NM_001281496 /// NM_001281497 /// NM_001281715 /// NM_002634 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016575 // histone deacetylation // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050847 // progesterone receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0071354 // cellular response to interleukin-6 // inferred from direct assay /// 0071897 // DNA biosynthetic process // inferred from electronic annotation /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 200660_at NM_005620 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005620.1 /DEF=Homo sapiens S100 calcium-binding protein A11 (calgizzarin) (S100A11), mRNA. /FEA=mRNA /GEN=S100A11 /PROD=S100 calcium-binding protein A11 /DB_XREF=gi:5032056 /UG=Hs.256290 S100 calcium-binding protein A11 (calgizzarin) /FL=gb:D49355.1 gb:BC001410.1 gb:D50374.1 gb:NM_005620.1 gb:D38583.1" NM_005620 S100 calcium binding protein A11 S100A11 6282 NM_005620 0007165 // signal transduction // traceable author statement /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from direct assay 200661_at NM_000308 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000308.1 /DEF=Homo sapiens protective protein for beta-galactosidase (galactosialidosis) (PPGB), mRNA. /FEA=mRNA /GEN=PPGB /PROD=protective protein for beta-galactosidase /DB_XREF=gi:4505988 /UG=Hs.118126 protective protein for beta-galactosidase (galactosialidosis) /FL=gb:BC000597.1 gb:M22960.1 gb:NM_000308.1" NM_000308 cathepsin A CTSA 5476 NM_000308 /// NM_001127695 /// NM_001167594 0006508 // proteolysis // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030239 // myofibril assembly // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005927 // muscle tendon junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030891 // VCB complex // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200662_s_at NM_014765 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014765.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 20 (yeast) homolog (KIAA0016), mRNA. /FEA=mRNA /GEN=KIAA0016 /PROD=translocase of outer mitochondrial membrane 20(yeast) homolog /DB_XREF=gi:7657256 /UG=Hs.75187 translocase of outer mitochondrial membrane 20 (yeast) homolog /FL=gb:BC000882.1 gb:D13641.1 gb:NM_014765.1" NM_014765 translocase of outer mitochondrial membrane 20 homolog (yeast) TOMM20 9804 NM_014765 0006605 // protein targeting // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // non-traceable author statement /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 200663_at NM_001780 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001780.1 /DEF=Homo sapiens CD63 antigen (melanoma 1 antigen) (CD63), mRNA. /FEA=mRNA /GEN=CD63 /PROD=CD63 antigen (melanoma 1 antigen) /DB_XREF=gi:4502678 /UG=Hs.76294 CD63 antigen (melanoma 1 antigen) /FL=gb:BC002349.1 gb:M59907.1 gb:NM_001780.1" NM_001780 CD63 molecule CD63 967 NM_001040034 /// NM_001257389 /// NM_001257390 /// NM_001257391 /// NM_001257392 /// NM_001257400 /// NM_001257401 /// NM_001267698 /// NM_001780 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0034613 // cellular protein localization // inferred from direct assay /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0048757 // pigment granule maturation // inferred from mutant phenotype /// 1900746 // regulation of vascular endothelial growth factor signaling pathway // inferred from mutant phenotype /// 2000680 // regulation of rubidium ion transport // inferred from direct assay /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from mutant phenotype "0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097487 // multivesicular body, internal vesicle // inferred from direct assay" 0005515 // protein binding // inferred from physical interaction 200664_s_at BG537255 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG537255 /FEA=EST /DB_XREF=gi:13529117 /DB_XREF=est:602565318F1 /CLONE=IMAGE:4689748 /UG=Hs.82646 DnaJ (Hsp40) homolog, subfamily B, member 1 /FL=gb:BC002352.1 gb:NM_006145.1 gb:D49547.1" BG537255 "DnaJ (Hsp40) homolog, subfamily B, member 1" DNAJB1 3337 NM_006145 /// XM_006722733 /// XM_006722734 /// XM_006722735 /// XM_006722736 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 200665_s_at NM_003118 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003118.1 /DEF=Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin) (SPARC), mRNA. /FEA=mRNA /GEN=SPARC /PROD=secreted protein, acidic, cysteine-rich(osteonectin) /DB_XREF=gi:4507170 /UG=Hs.111779 secreted protein, acidic, cysteine-rich (osteonectin) /FL=gb:BC004974.1 gb:J03040.1 gb:NM_003118.1" NM_003118 "secreted protein, acidic, cysteine-rich (osteonectin)" SPARC 6678 NM_003118 0001503 // ossification // inferred from electronic annotation /// 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043312 // neutrophil degranulation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045088 // regulation of innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // non-traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031941 // filamentous actin // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005518 // collagen binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 200666_s_at NM_006145 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006145.1 /DEF=Homo sapiens heat shock 40kD protein 1 (HSPF1), mRNA. /FEA=mRNA /GEN=HSPF1 /PROD=heat shock 40kD protein 1 /DB_XREF=gi:5453689 /UG=Hs.82646 DnaJ (Hsp40) homolog, subfamily B, member 1 /FL=gb:BC002352.1 gb:NM_006145.1 gb:D49547.1" NM_006145 "DnaJ (Hsp40) homolog, subfamily B, member 1" DNAJB1 3337 NM_006145 /// XM_006722733 /// XM_006722734 /// XM_006722735 /// XM_006722736 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 200667_at BF448062 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF448062 /FEA=EST /DB_XREF=gi:11513123 /DB_XREF=est:7q97h09.x1 /CLONE=IMAGE:3706600 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1 BF448062 ubiquitin-conjugating enzyme E2D 3 UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 /// XM_005263200 /// XM_005263205 /// XM_006714297 /// XM_006714298 /// XM_006714299 /// XM_006714300 /// XM_006714301 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement" 0005654 // nucleoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 200668_s_at BC003395 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003395.1 /DEF=Homo sapiens, ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45), clone MGC:5416, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin-conjugating enzyme E2D 3 (homologousto yeast UBC45) /DB_XREF=gi:13097281 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1" BC003395 ubiquitin-conjugating enzyme E2D 3 UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 /// XM_005263200 /// XM_005263205 /// XM_006714297 /// XM_006714298 /// XM_006714299 /// XM_006714300 /// XM_006714301 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement" 0005654 // nucleoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 200669_s_at NM_003340 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003340.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) (UBE2D3), mRNA. /FEA=mRNA /GEN=UBE2D3 /PROD=ubiquitin-conjugating enzyme E2D 3 (homologousto yeast UBC45) /DB_XREF=gi:4507776 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1" NM_003340 ubiquitin-conjugating enzyme E2D 3 UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 /// XM_005263200 /// XM_005263205 /// XM_006714297 /// XM_006714298 /// XM_006714299 /// XM_006714300 /// XM_006714301 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement" 0005654 // nucleoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 200670_at NM_005080 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005080.1 /DEF=Homo sapiens X-box binding protein 1 (XBP1), mRNA. /FEA=mRNA /GEN=XBP1 /PROD=X-box binding protein 1 /DB_XREF=gi:4827057 /UG=Hs.149923 X-box binding protein 1 /FL=gb:BC000938.1 gb:M31627.1 gb:NM_005080.1" NM_005080 X-box binding protein 1 XBP1 7494 NM_001079539 /// NM_005080 "0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060096 // serotonin secretion, neurotransmission // inferred from electronic annotation /// 0060691 // epithelial cell maturation involved in salivary gland development // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 1900103 // positive regulation of endoplasmic reticulum unfolded protein response // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200671_s_at N92501 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N92501 /FEA=EST /DB_XREF=gi:1264810 /DB_XREF=est:zb28a07.s1 /CLONE=IMAGE:304884 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 /FL=gb:M96803.1 gb:NM_003128.1" N92501 "spectrin, beta, non-erythrocytic 1" SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200672_x_at NM_003128 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003128.1 /DEF=Homo sapiens spectrin, beta, non-erythrocytic 1 (SPTBN1), mRNA. /FEA=mRNA /GEN=SPTBN1 /PROD=spectrin, beta, non-erythrocytic 1 /DB_XREF=gi:4507194 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 /FL=gb:M96803.1 gb:NM_003128.1" NM_003128 "spectrin, beta, non-erythrocytic 1" SPTBN1 6711 NM_003128 /// NM_178313 /// XM_005264517 /// XM_005264518 /// XM_006712087 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0007009 // plasma membrane organization // inferred from mutant phenotype /// 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0051693 // actin filament capping // inferred from electronic annotation /// 0071709 // membrane assembly // inferred from mutant phenotype /// 0072661 // protein targeting to plasma membrane // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // inferred from electronic annotation /// 0014731 // spectrin-associated cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030673 // axolemma // inferred from sequence or structural similarity /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0032437 // cuticular plate // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0030506 // ankyrin binding // non-traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200673_at NM_014713 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014713.2 /DEF=Homo sapiens lysosomal-associated protein transmembrane 4 alpha (MBNT), mRNA. /FEA=mRNA /GEN=MBNT /PROD=lysosomal-associated protein transmembrane 4alpha /DB_XREF=gi:13518239 /UG=Hs.111894 lysosomal-associated protein transmembrane 4 alpha /FL=gb:BC000421.1 gb:BC003158.1 gb:NM_014713.2 gb:D14696.1" NM_014713 lysosomal protein transmembrane 4 alpha LAPTM4A 9741 NM_014713 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200674_s_at NM_000994 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000994.1 /DEF=Homo sapiens ribosomal protein L32 (RPL32), mRNA. /FEA=mRNA /GEN=RPL32 /PROD=ribosomal protein L32 /DB_XREF=gi:4506634 /UG=Hs.169793 ribosomal protein L32 /FL=gb:NM_000994.1" NM_000994 ribosomal protein L32 RPL32 6161 NM_000994 /// NM_001007073 /// NM_001007074 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200675_at NM_004356 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004356.1 /DEF=Homo sapiens CD81 antigen (target of antiproliferative antibody 1) (CD81), mRNA. /FEA=mRNA /GEN=CD81 /PROD=CD81 antigen (target of antiproliferativeantibody 1) /DB_XREF=gi:4757943 /UG=Hs.54457 CD81 antigen (target of antiproliferative antibody 1) /FL=gb:BC002978.1 gb:M33680.1 gb:NM_004356.1" NM_004356 CD81 molecule CD81 975 NM_004356 /// XM_005253260 0000187 // activation of MAPK activity // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0008104 // protein localization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043128 // positive regulation of 1-phosphatidylinositol 4-kinase activity // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from direct assay /// 0046718 // viral entry into host cell // traceable author statement /// 0046813 // receptor-mediated virion attachment to host cell // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay 200676_s_at NM_003347 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003347.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), mRNA. /FEA=mRNA /GEN=UBE2L3 /PROD=ubiquitin-conjugating enzyme E2L 3 /DB_XREF=gi:4507788 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1" NM_003347 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 "0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay" 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200677_at NM_004339 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004339.2 /DEF=Homo sapiens pituitary tumor-transforming 1 interacting protein (PTTG1IP), mRNA. /FEA=mRNA /GEN=PTTG1IP /PROD=pituitary tumor-transforming protein1-interacting protein precursor /DB_XREF=gi:11038670 /UG=Hs.111126 pituitary tumor-transforming 1 interacting protein /FL=gb:NM_004339.2 gb:BC000415.1 gb:AF149785.1" NM_004339 pituitary tumor-transforming 1 interacting protein PTTG1IP 754 NM_001286822 /// NM_004339 /// NR_104597 0006606 // protein import into nucleus // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation 200678_x_at NM_002087 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002087.1 /DEF=Homo sapiens granulin (GRN), mRNA. /FEA=mRNA /GEN=GRN /PROD=granulin /DB_XREF=gi:4504150 /UG=Hs.180577 granulin /FL=gb:M75161.1 gb:AF055008.1 gb:NM_002087.1" NM_002087 granulin GRN 2896 NM_001012479 /// NM_002087 /// XM_005257253 0001835 // blastocyst hatching // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200679_x_at BE311760 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE311760 /FEA=EST /DB_XREF=gi:9148272 /DB_XREF=est:601143587F1 /CLONE=IMAGE:3507284 /UG=Hs.274472 high-mobility group (nonhistone chromosomal) protein 1 /FL=gb:BC003378.1 gb:NM_002128.1 gb:D63874.1 BE311760 high mobility group box 1 HMGB1 3146 NM_002128 /// XM_005266363 /// XM_005266365 /// XM_005266368 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001773 // myeloid dendritic cell activation // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from expression pattern /// 0006265 // DNA topological change // inferred from sequence or structural similarity /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006310 // DNA recombination // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051103 // DNA ligation involved in DNA repair // inferred from sequence or structural similarity /// 2000426 // negative regulation of apoptotic cell clearance // inferred from electronic annotation" 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from mutant phenotype /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0042056 // chemoattractant activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction" 200680_x_at NM_002128 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002128.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 1 (HMG1), mRNA. /FEA=mRNA /GEN=HMG1 /PROD=high-mobility group (nonhistone chromosomal)protein 1 /DB_XREF=gi:4504424 /UG=Hs.274472 high-mobility group (nonhistone chromosomal) protein 1 /FL=gb:BC003378.1 gb:NM_002128.1 gb:D63874.1" NM_002128 high mobility group box 1 HMGB1 3146 NM_002128 /// XM_005266363 /// XM_005266365 /// XM_005266368 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001773 // myeloid dendritic cell activation // inferred from sequence or structural similarity /// 0002407 // dendritic cell chemotaxis // inferred from sequence or structural similarity /// 0002437 // inflammatory response to antigenic stimulus // inferred from expression pattern /// 0006265 // DNA topological change // inferred from sequence or structural similarity /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006310 // DNA recombination // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from sequence or structural similarity /// 0051103 // DNA ligation involved in DNA repair // inferred from sequence or structural similarity /// 2000426 // negative regulation of apoptotic cell clearance // inferred from electronic annotation" 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from sequence or structural similarity /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from mutant phenotype /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0042056 // chemoattractant activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050786 // RAGE receptor binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction" 200681_at NM_006708 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006708.1 /DEF=Homo sapiens glyoxalase I (GLO1), mRNA. /FEA=mRNA /GEN=GLO1 /PROD=glyoxalase I /DB_XREF=gi:5729841 /UG=Hs.75207 glyoxalase I /FL=gb:BC001741.1 gb:L07837.1 gb:NM_006708.1" NM_006708 glyoxalase I GLO1 2739 NM_006708 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009438 // methylglyoxal metabolic process // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004462 // lactoylglutathione lyase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200682_s_at BG531983 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG531983 /FEA=EST /DB_XREF=gi:13523521 /DB_XREF=est:602561007F1 /CLONE=IMAGE:4699176 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 BG531983 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 "0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay" 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200683_s_at BE964689 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE964689 /FEA=EST /DB_XREF=gi:11768267 /DB_XREF=est:601658226R1 /CLONE=IMAGE:3885630 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 BE964689 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 "0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay" 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200684_s_at AI819709 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI819709 /FEA=EST /DB_XREF=gi:5438788 /DB_XREF=est:wj77c07.x1 /CLONE=IMAGE:2408844 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 AI819709 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_001256355 /// NM_001256356 /// NM_003347 /// NM_198157 /// NR_028436 /// NR_046082 "0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay" 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200685_at AU146237 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU146237 /FEA=EST /DB_XREF=gi:11007758 /DB_XREF=est:AU146237 /CLONE=HEMBA1007233 /UG=Hs.11482 splicing factor, arginineserine-rich 11 /FL=gb:M74002.1 gb:NM_004768.1" AU146237 serine/arginine-rich splicing factor 11 SRSF11 9295 NM_001190987 /// NM_004768 /// XM_005271338 /// XM_005271339 /// XM_006711037 /// XM_006711038 /// XM_006711039 /// XM_006711040 /// XM_006711041 /// XR_426640 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200686_s_at NM_004768 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004768.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 11 (SFRS11), mRNA. /FEA=mRNA /GEN=SFRS11 /PROD=splicing factor, arginineserine-rich 11 /DB_XREF=gi:4759099 /UG=Hs.11482 splicing factor, arginineserine-rich 11 /FL=gb:M74002.1 gb:NM_004768.1" NM_004768 serine/arginine-rich splicing factor 11 SRSF11 9295 NM_001190987 /// NM_004768 /// XM_005271338 /// XM_005271339 /// XM_006711037 /// XM_006711038 /// XM_006711039 /// XM_006711040 /// XM_006711041 /// XR_426640 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200687_s_at NM_012426 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012426.1 /DEF=Homo sapiens splicing factor 3b, subunit 3, 130kD (SF3B3), mRNA. /FEA=mRNA /GEN=SF3B3 /PROD=splicing factor 3b, subunit 3, 130kD /DB_XREF=gi:11034822 /UG=Hs.195614 splicing factor 3b, subunit 3, 130kD /FL=gb:NM_012426.1 gb:BC000463.1 gb:BC003146.1 gb:D13642.1 gb:D87686.1" NM_012426 "splicing factor 3b, subunit 3, 130kDa" SF3B3 23450 NM_012426 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200688_at D13642 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D13642.1 /DEF=Human mRNA for KIAA0017 gene, complete cds. /FEA=mRNA /GEN=KIAA0017 /DB_XREF=gi:285998 /UG=Hs.195614 splicing factor 3b, subunit 3, 130kD /FL=gb:NM_012426.1 gb:BC000463.1 gb:BC003146.1 gb:D13642.1 gb:D87686.1" D13642 "splicing factor 3b, subunit 3, 130kDa" SF3B3 23450 NM_012426 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200689_x_at NM_001404 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001404.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 gamma (EEF1G), mRNA. /FEA=mRNA /GEN=EEF1G /PROD=eukaryotic translation elongation factor 1gamma /DB_XREF=gi:4503480 /UG=Hs.2186 eukaryotic translation elongation factor 1 gamma /FL=gb:BC000384.1 gb:BC004189.1 gb:BC004215.1 gb:NM_001404.1" NM_001404 eukaryotic translation elongation factor 1 gamma /// microRNA 3654 EEF1G /// MIR3654 1937 /// 100500804 NM_001404 /// NR_037427 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200690_at AA927701 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA927701 /FEA=EST /DB_XREF=gi:3076521 /DB_XREF=est:om72d09.s1 /CLONE=IMAGE:1552721 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1 AA927701 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement" 200691_s_at BC000478 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000478.1 /DEF=Homo sapiens, heat shock 70kD protein 9B (mortalin-2), clone MGC:8684, mRNA, complete cds. /FEA=mRNA /PROD=heat shock 70kD protein 9B (mortalin-2) /DB_XREF=gi:12653414 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1" BC000478 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement" 200692_s_at NM_004134 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004134.1 /DEF=Homo sapiens heat shock 70kD protein 9B (mortalin-2) (HSPA9B), mRNA. /FEA=mRNA /GEN=HSPA9B /PROD=heat shock 70kD protein 9B (mortalin-2) /DB_XREF=gi:4758569 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1" NM_004134 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0000902 // cell morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement" 200693_at NM_006826 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006826.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide (YWHAQ), mRNA. /FEA=mRNA /GEN=YWHAQ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, theta polypeptide /DB_XREF=gi:5803226 /UG=Hs.74405 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide /FL=gb:NM_006826.1" NM_006826 "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta" YWHAQ 10971 NM_006826 "0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 200694_s_at NM_020414 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020414.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 (DDX24), mRNA. /FEA=mRNA /GEN=DDX24 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /DB_XREF=gi:13787212 /UG=Hs.155986 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /FL=gb:AL136886.1 gb:NM_020414.2 gb:AF214731.1" NM_020414 DEAD (Asp-Glu-Ala-Asp) box helicase 24 DDX24 57062 NM_020414 0003351 // epithelial cilium movement // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016070 // RNA metabolic process // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0072372 // primary cilium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200695_at NM_014225 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014225.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA. /FEA=mRNA /GEN=PPP2R1A /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit A (PR 65), alpha isoform /DB_XREF=gi:7657474 /UG=Hs.173902 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform /FL=gb:J02902.1 gb:NM_014225.1" NM_014225 "protein phosphatase 2, regulatory subunit A, alpha" PPP2R1A 5518 NM_014225 /// NR_033500 "0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000188 // inactivation of MAPK activity // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006275 // regulation of DNA replication // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006470 // protein dephosphorylation // traceable author statement /// 0006672 // ceramide metabolic process // non-traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007059 // chromosome segregation // inferred from direct assay /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0008380 // RNA splicing // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019932 // second-messenger-mediated signaling // non-traceable author statement /// 0030111 // regulation of Wnt signaling pathway // non-traceable author statement /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0040008 // regulation of growth // non-traceable author statement /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // non-traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // non-traceable author statement /// 0070262 // peptidyl-serine dephosphorylation // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation" "0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // non-traceable author statement /// 0016020 // membrane // non-traceable author statement" 0003823 // antigen binding // inferred from physical interaction /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200696_s_at NM_000177 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000177.1 /DEF=Homo sapiens gelsolin (amyloidosis, Finnish type) (GSN), mRNA. /FEA=mRNA /GEN=GSN /PROD=gelsolin (amyloidosis, Finnish type) /DB_XREF=gi:4504164 /UG=Hs.290070 gelsolin (amyloidosis, Finnish type) /FL=gb:NM_000177.1" NM_000177 gelsolin GSN 2934 NM_000177 /// NM_001127662 /// NM_001127663 /// NM_001127664 /// NM_001127665 /// NM_001127666 /// NM_001127667 /// NM_001258029 /// NM_001258030 /// NM_198252 /// XM_005251940 /// XM_005251943 /// XM_005251944 /// XM_005251945 /// XM_006717075 /// XM_006717076 /// XM_006717077 /// XM_006717078 /// XM_006717079 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051014 // actin filament severing // inferred from direct assay /// 0051014 // actin filament severing // inferred from sequence or structural similarity /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200697_at NM_000188 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000188.1 /DEF=Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=HK1 /PROD=hexokinase 1 /DB_XREF=gi:4504390 /UG=Hs.118625 hexokinase 1 /FL=gb:M75126.1 gb:NM_000188.1" NM_000188 hexokinase 1 HK1 3098 NM_000188 /// NM_033496 /// NM_033497 /// NM_033498 /// NM_033500 /// XM_005269735 /// XM_005269736 /// XM_005269737 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006096 // glycolytic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019318 // hexose metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // not recorded /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement /// 0051156 // glucose 6-phosphate metabolic process // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004340 // glucokinase activity // not recorded /// 0004396 // hexokinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded" 200698_at AL542253 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL542253 /FEA=EST /DB_XREF=gi:12874115 /DB_XREF=est:AL542253 /CLONE=CS0DE008YC08 (3 prime) /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 AL542253 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200699_at BE962456 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE962456 /FEA=EST /DB_XREF=gi:11765376 /DB_XREF=est:601655751R1 /CLONE=IMAGE:3846156 /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 BE962456 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200700_s_at NM_006854 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006854.2 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (KDELR2), mRNA. /FEA=mRNA /GEN=KDELR2 /PROD=KDEL receptor 2 /DB_XREF=gi:8051609 /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2" NM_006854 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200701_at NM_006432 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006432.1 /DEF=Homo sapiens epididymal secretory protein (19.5kD) (HE1), mRNA. /FEA=mRNA /GEN=HE1 /PROD=epididymal secretory protein (19.5kD) /DB_XREF=gi:5453677 /UG=Hs.119529 epididymal secretory protein (19.5kD) /FL=gb:BC002532.1 gb:NM_006432.1" NM_006432 "Niemann-Pick disease, type C2" NPC2 10577 NM_006432 /// XM_006720004 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0015914 // phospholipid transport // traceable author statement /// 0019747 // regulation of isoprenoid metabolic process // traceable author statement /// 0030301 // cholesterol transport // inferred from direct assay /// 0032366 // intracellular sterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from genetic interaction /// 0033344 // cholesterol efflux // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0046836 // glycolipid transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction 200702_s_at BG421209 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG421209 /FEA=EST /DB_XREF=gi:13327715 /DB_XREF=est:602451696F1 /CLONE=IMAGE:4590215 /UG=Hs.155986 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /FL=gb:AL136886.1 gb:NM_020414.2 gb:AF214731.1 BG421209 DEAD (Asp-Glu-Ala-Asp) box helicase 24 DDX24 57062 NM_020414 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016070 // RNA metabolic process // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200703_at NM_003746 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003746.1 /DEF=Homo sapiens dynein, cytoplasmic, light polypeptide (PIN), mRNA. /FEA=mRNA /GEN=PIN /PROD=dynein, cytoplasmic, light polypeptide /DB_XREF=gi:4505812 /UG=Hs.5120 dynein, cytoplasmic, light polypeptide /FL=gb:U32944.1 gb:NM_003746.1" NM_003746 "dynein, light chain, LC8-type 1" DYNLL1 8655 NM_001037494 /// NM_001037495 /// NM_003746 "0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement" 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 200704_at AB034747 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB034747.1 /DEF=Homo sapiens SIMPLE mRNA for small integral membrane protein of lysosomelate endosome, complete cds. /FEA=mRNA /GEN=SIMPLE /PROD=small integral membrane protein of lysosomelateendosome /DB_XREF=gi:12862475 /UG=Hs.76507 LPS-induced TNF-alpha factor /FL=gb:AB034747.1 gb:U77396.1 gb:AF010312.1 gb:NM_004862.1" AB034747 lipopolysaccharide-induced TNF factor LITAF 9516 NM_001136472 /// NM_001136473 /// NM_004862 /// NR_024320 /// XM_006720982 /// XM_006720983 /// XM_006720984 /// XM_006720985 "0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 200705_s_at NM_001959 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001959.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 beta 2 (EEF1B2), mRNA. /FEA=mRNA /GEN=EEF1B2 /PROD=eukaryotic translation elongation factor 1 beta2 /DB_XREF=gi:4503476 /UG=Hs.275959 eukaryotic translation elongation factor 1 beta 2 /FL=gb:BC004931.1 gb:NM_001959.1" NM_001959 "eukaryotic translation elongation factor 1 beta 2 /// small nucleolar RNA, H/ACA box 41" EEF1B2 /// SNORA41 1933 /// 619569 NM_001037663 /// NM_001959 /// NM_021121 /// NR_002590 0006412 // translation // traceable author statement /// 0006414 // translational elongation // non-traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // non-traceable author statement 0003746 // translation elongation factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200706_s_at NM_004862 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004862.1 /DEF=Homo sapiens LPS-induced TNF-alpha factor (PIG7), mRNA. /FEA=mRNA /GEN=PIG7 /PROD=LPS-induced TNF-alpha factor /DB_XREF=gi:4758913 /UG=Hs.76507 LPS-induced TNF-alpha factor /FL=gb:AB034747.1 gb:U77396.1 gb:AF010312.1 gb:NM_004862.1" NM_004862 lipopolysaccharide-induced TNF factor LITAF 9516 NM_001136472 /// NM_001136473 /// NM_004862 /// NR_024320 /// XM_006720982 /// XM_006720983 /// XM_006720984 /// XM_006720985 "0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 200707_at NM_002743 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002743.1 /DEF=Homo sapiens protein kinase C substrate 80K-H (PRKCSH), mRNA. /FEA=mRNA /GEN=PRKCSH /PROD=protein kinase C substrate 80K-H /DB_XREF=gi:4506076 /UG=Hs.1432 protein kinase C substrate 80K-H /FL=gb:J03075.1 gb:NM_002743.1 gb:AF144075.1" NM_002743 protein kinase C substrate 80K-H PRKCSH 5589 NM_001001329 /// NM_001289102 /// NM_001289103 /// NM_001289104 /// NM_002743 /// XM_006722795 /// XM_006722796 /// XM_006722797 /// XM_006722798 /// XR_430144 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006491 // N-glycan processing // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from physical interaction 200708_at NM_002080 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002080.1 /DEF=Homo sapiens glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) (GOT2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=GOT2 /PROD=aspartate aminotransferase 2 precursor /DB_XREF=gi:4504068 /UG=Hs.170197 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) /FL=gb:BC000525.1 gb:M22632.1 gb:NM_002080.1" NM_002080 "glutamic-oxaloacetic transaminase 2, mitochondrial" GOT2 2806 NM_001286220 /// NM_002080 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006531 // aspartate metabolic process // inferred from sequence or structural similarity /// 0006532 // aspartate biosynthetic process // inferred from electronic annotation /// 0006533 // aspartate catabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from expression pattern /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0019550 // glutamate catabolic process to aspartate // inferred from electronic annotation /// 0019551 // glutamate catabolic process to 2-oxoglutarate // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from direct assay /// 0097052 // L-kynurenine metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // not recorded /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // inferred from direct assay /// 0004069 // L-aspartate:2-oxoglutarate aminotransferase activity // inferred from sequence or structural similarity /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016212 // kynurenine-oxoglutarate transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0080130 // L-phenylalanine:2-oxoglutarate aminotransferase activity // inferred from electronic annotation 200709_at NM_000801 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000801.1 /DEF=Homo sapiens FK506-binding protein 1A (12kD) (FKBP1A), mRNA. /FEA=mRNA /GEN=FKBP1A /PROD=FK506-binding protein 1A (12kD) /DB_XREF=gi:4503724 /UG=Hs.752 FK506-binding protein 1A (12kD) /FL=gb:BC001925.1 gb:M34539.1 gb:NM_000801.1" NM_000801 "FK506 binding protein 1A, 12kDa /// uncharacterized LOC101929368" FKBP1A /// LOC101929368 2280 /// 101929368 NM_000801 /// NM_001199786 /// NM_054014 /// XR_245428 /// XR_247917 /// XR_253167 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // non-traceable author statement /// 0006458 // 'de novo' protein folding // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0018208 // peptidyl-proline modification // /// 0022417 // protein maturation by protein folding // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from genetic interaction /// 0032925 // regulation of activin receptor signaling pathway // inferred from direct assay /// 0034205 // beta-amyloid formation // inferred from direct assay /// 0042026 // protein refolding // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043206 // extracellular fibril organization // inferred from direct assay /// 0050776 // regulation of immune response // inferred from mutant phenotype /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity /// 0061077 // chaperone-mediated protein folding // not recorded /// 0070588 // calcium ion transmembrane transport // non-traceable author statement /// 1902991 // regulation of amyloid precursor protein catabolic process // inferred from genetic interaction /// 1990000 // amyloid fibril formation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0014802 // terminal cisterna // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from direct assay /// 0030424 // axon // /// 0033017 // sarcoplasmic reticulum membrane // /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005024 // transforming growth factor beta-activated receptor activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005527 // macrolide binding // non-traceable author statement /// 0005528 // FK506 binding // inferred from direct assay /// 0005528 // FK506 binding // non-traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019855 // calcium channel inhibitor activity // inferred from direct assay /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046332 // SMAD binding // inferred from physical interaction /// 0048185 // activin binding // inferred from physical interaction 200710_at NM_000018 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000018.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, very long chain (ACADVL), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADVL /PROD=acyl-Coenzyme A dehydrogenase, very long chainprecursor /DB_XREF=gi:4557234 /UG=Hs.82208 acyl-Coenzyme A dehydrogenase, very long chain /FL=gb:D43682.1 gb:BC000399.1 gb:NM_000018.1" NM_000018 "acyl-CoA dehydrogenase, very long chain" ACADVL 37 NM_000018 /// NM_001033859 /// NM_001270447 /// NM_001270448 /// XM_006721516 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015980 // energy derivation by oxidation of organic compounds // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0046322 // negative regulation of fatty acid oxidation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090181 // regulation of cholesterol metabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay "0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0004466 // long-chain-acyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 200711_s_at NM_003197 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003197.2 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 1-like (TCEB1L), mRNA. /FEA=mRNA /GEN=TCEB1L /PROD=transcription elongation factor B polypeptide1-like /DB_XREF=gi:6006030 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2" NM_003197 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 200712_s_at AI633566 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI633566 /FEA=EST /DB_XREF=gi:4684896 /DB_XREF=est:th68f09.x1 /CLONE=IMAGE:2123849 /UG=Hs.234279 microtubule-associated protein, RPEB family, member 1 /FL=gb:NM_012325.1 gb:U24166.1" AI633566 "microtubule-associated protein, RP/EB family, member 1" MAPRE1 22919 NM_012325 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0031113 // regulation of microtubule polymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0035372 // protein localization to microtubule // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0030981 // cortical microtubule cytoskeleton // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 200713_s_at NM_012325 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012325.1 /DEF=Homo sapiens microtubule-associated protein, RPEB family, member 1 (MAPRE1), mRNA. /FEA=mRNA /GEN=MAPRE1 /PROD=microtubule-associated protein, RPEB family,member 1 /DB_XREF=gi:6912493 /UG=Hs.234279 microtubule-associated protein, RPEB family, member 1 /FL=gb:NM_012325.1 gb:U24166.1" NM_012325 "microtubule-associated protein, RP/EB family, member 1" MAPRE1 22919 NM_012325 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0031113 // regulation of microtubule polymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0035372 // protein localization to microtubule // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0030981 // cortical microtubule cytoskeleton // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 200714_x_at NM_006812 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006812.1 /DEF=Homo sapiens amplified in osteosarcoma (OS-9), mRNA. /FEA=mRNA /GEN=OS-9 /PROD=amplified in osteosarcoma /DB_XREF=gi:5803108 /UG=Hs.76228 amplified in osteosarcoma /FL=gb:U41635.1 gb:AB002806.1 gb:NM_006812.1" NM_006812 "osteosarcoma amplified 9, endoplasmic reticulum lectin" OS9 10956 NM_001017956 /// NM_001017957 /// NM_001017958 /// NM_001261420 /// NM_001261421 /// NM_001261422 /// NM_001261423 /// NM_006812 /// XM_005268581 /// XM_006719200 /// XM_006719201 0006605 // protein targeting // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype 0000836 // Hrd1p ubiquitin ligase complex // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0002020 // protease binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200715_x_at BC000514 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000514.1 /DEF=Homo sapiens, ribosomal protein L13a, clone MGC:8547, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L13a /DB_XREF=gi:12653484 /UG=Hs.119122 ribosomal protein L13a /FL=gb:BC000514.1 gb:NM_012423.1" BC000514 "ribosomal protein L13a /// small nucleolar RNA, C/D box 32A /// small nucleolar RNA, C/D box 33 /// small nucleolar RNA, C/D box 34 /// small nucleolar RNA, C/D box 35A" RPL13A /// SNORD32A /// SNORD33 /// SNORD34 /// SNORD35A 23521 /// 26816 /// 26817 /// 26818 /// 26819 NM_001270491 /// NM_012423 /// NR_000018 /// NR_000019 /// NR_000020 /// NR_000021 /// NR_073024 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1901194 // negative regulation of formation of translation preinitiation complex // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200716_x_at NM_012423 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012423.1 /DEF=Homo sapiens ribosomal protein L13a (RPL13A), mRNA. /FEA=mRNA /GEN=RPL13A /PROD=ribosomal protein L13a /DB_XREF=gi:6912633 /UG=Hs.119122 ribosomal protein L13a /FL=gb:BC000514.1 gb:NM_012423.1" NM_012423 "ribosomal protein L13a /// ribosomal protein L13a pseudogene 5 /// small nucleolar RNA, C/D box 32A /// small nucleolar RNA, C/D box 33 /// small nucleolar RNA, C/D box 34 /// small nucleolar RNA, C/D box 35A" RPL13A /// RPL13AP5 /// SNORD32A /// SNORD33 /// SNORD34 /// SNORD35A 23521 /// 26816 /// 26817 /// 26818 /// 26819 /// 728658 NM_001270491 /// NM_012423 /// NR_000018 /// NR_000019 /// NR_000020 /// NR_000021 /// NR_026712 /// NR_073024 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 1901194 // negative regulation of formation of translation preinitiation complex // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200717_x_at NM_000971 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000971.1 /DEF=Homo sapiens ribosomal protein L7 (RPL7), mRNA. /FEA=mRNA /GEN=RPL7 /PROD=ribosomal protein L7 /DB_XREF=gi:4506658 /UG=Hs.153 ribosomal protein L7 /FL=gb:L16558.1 gb:NM_000971.1" NM_000971 ribosomal protein L7 RPL7 6129 NM_000971 /// XM_006716463 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200718_s_at AA927664 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA927664 /FEA=EST /DB_XREF=gi:3076484 /DB_XREF=est:om71h10.s1 /CLONE=IMAGE:1552675 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2" AA927664 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 200719_at BE964043 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE964043 /FEA=EST /DB_XREF=gi:11767371 /DB_XREF=est:601657616R1 /CLONE=IMAGE:3875955 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2" BE964043 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031146 // SCF-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 200720_s_at AL532341 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL532341 /FEA=EST /DB_XREF=gi:12795834 /DB_XREF=est:AL532341 /CLONE=CS0DM014YJ21 (5 prime) /UG=Hs.153961 ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) /FL=gb:BC000693.1 gb:NM_005736.2" AL532341 "ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)" ACTR1A 10121 NM_005736 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200721_s_at NM_005736 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005736.2 /DEF=Homo sapiens ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) (ACTR1A), mRNA. /FEA=mRNA /GEN=ACTR1A /PROD=actin-related protein 1A /DB_XREF=gi:13325058 /UG=Hs.153961 ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) /FL=gb:BC000693.1 gb:NM_005736.2" NM_005736 "ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)" ACTR1A 10121 NM_005736 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200722_s_at BG258784 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG258784 /FEA=EST /DB_XREF=gi:12768600 /DB_XREF=est:602378049F1 /CLONE=IMAGE:4508820 /UG=Hs.278672 membrane component, chromosome 11, surface marker 1 /FL=gb:BC001731.1 gb:NM_005898.1" BG258784 cell cycle associated protein 1 CAPRIN1 4076 NM_005898 /// NM_203364 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003723 // RNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 200723_s_at NM_005898 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005898.1 /DEF=Homo sapiens membrane component, chromosome 11, surface marker 1 (M11S1), mRNA. /FEA=mRNA /GEN=M11S1 /PROD=membrane component, chromosome 11, surfacemarker 1 /DB_XREF=gi:5174502 /UG=Hs.278672 membrane component, chromosome 11, surface marker 1 /FL=gb:BC001731.1 gb:NM_005898.1" NM_005898 cell cycle associated protein 1 CAPRIN1 4076 NM_005898 /// NM_203364 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003723 // RNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 200724_at BC003358 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003358.1 /DEF=Homo sapiens, ribosomal protein L10, clone MGC:5189, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L10 /DB_XREF=gi:13097176 /UG=Hs.29797 ribosomal protein L10 /FL=gb:BC003358.1 gb:M73791.1 gb:M64241.1 gb:NM_006013.1" BC003358 "ribosomal protein L10 /// small nucleolar RNA, H/ACA box 70" RPL10 /// SNORA70 6134 /// 26778 NM_001256577 /// NM_001256580 /// NM_006013 /// NR_000011 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200725_x_at NM_006013 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006013.1 /DEF=Homo sapiens ribosomal protein L10 (RPL10), mRNA. /FEA=mRNA /GEN=RPL10 /PROD=ribosomal protein L10 /DB_XREF=gi:5174430 /UG=Hs.29797 ribosomal protein L10 /FL=gb:BC003358.1 gb:M73791.1 gb:M64241.1 gb:NM_006013.1" NM_006013 "ribosomal protein L10 /// small nucleolar RNA, H/ACA box 70" RPL10 /// SNORA70 6134 /// 26778 NM_001256577 /// NM_001256580 /// NM_006013 /// NR_000011 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200726_at NM_002710 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002710.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, gamma isoform (PPP1CC), mRNA. /FEA=mRNA /GEN=PPP1CC /PROD=protein phosphatase 1, catalytic subunit, gammaisoform /DB_XREF=gi:4506006 /UG=Hs.79081 protein phosphatase 1, catalytic subunit, gamma isoform /FL=gb:NM_002710.1" NM_002710 "protein phosphatase 1, catalytic subunit, gamma isozyme" PPP1CC 5501 NM_001244974 /// NM_002710 /// XM_006719469 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation "0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0043234 // protein complex // inferred from mutant phenotype /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay" 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 200727_s_at AA699583 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA699583 /FEA=EST /DB_XREF=gi:2703730 /DB_XREF=est:zi42g07.s1 /CLONE=IMAGE:433500 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1" AA699583 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from reviewed computational analysis /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030478 // actin cap // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200728_at BE566290 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE566290 /FEA=EST /DB_XREF=gi:9810010 /DB_XREF=est:601339864F1 /CLONE=IMAGE:3682406 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1" BE566290 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from reviewed computational analysis /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030478 // actin cap // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200729_s_at NM_005722 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005722.1 /DEF=Homo sapiens ARP2 (actin-related protein 2, yeast) homolog (ACTR2), mRNA. /FEA=mRNA /GEN=ACTR2 /PROD=ARP2 (actin-related protein 2, yeast) homolog /DB_XREF=gi:5031570 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1" NM_005722 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from reviewed computational analysis /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030478 // actin cap // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200730_s_at BF576710 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF576710 /FEA=EST /DB_XREF=gi:11650422 /DB_XREF=est:602135085F1 /CLONE=IMAGE:4290141 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1" BF576710 "protein tyrosine phosphatase type IVA, member 1" PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200731_s_at AW165960 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW165960 /FEA=EST /DB_XREF=gi:6397485 /DB_XREF=est:xf43a12.x1 /CLONE=IMAGE:2620798 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1" AW165960 "protein tyrosine phosphatase type IVA, member 1" PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200732_s_at AL578310 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL578310 /FEA=EST /DB_XREF=gi:12942259 /DB_XREF=est:AL578310 /CLONE=CS0DK010YM06 (3 prime) /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1" AL578310 "protein tyrosine phosphatase type IVA, member 1" PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200733_s_at U48296 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U48296.1 /DEF=Homo sapiens protein tyrosine phosphatase PTPCAAX1 (hPTPCAAX1) mRNA, complete cds. /FEA=mRNA /GEN=hPTPCAAX1 /PROD=protein tyrosine phosphatase PTPCAAX1 /DB_XREF=gi:1777754 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1" U48296 "protein tyrosine phosphatase type IVA, member 1" PTP4A1 7803 NM_003463 /// XM_006715563 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200734_s_at BG341906 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG341906 /FEA=EST /DB_XREF=gi:13148344 /DB_XREF=est:602463246F1 /CLONE=IMAGE:4576258 /UG=Hs.119177 ADP-ribosylation factor 3 /FL=gb:M74491.1 gb:NM_001659.1 BG341906 ADP-ribosylation factor 3 ARF3 377 NM_001659 /// XM_005268856 /// XM_006719391 0006184 // GTP catabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 200735_x_at NM_005594 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005594.1 /DEF=Homo sapiens nascent-polypeptide-associated complex alpha polypeptide (NACA), mRNA. /FEA=mRNA /GEN=NACA /PROD=nascent-polypeptide-associated complex alphapolypeptide /DB_XREF=gi:5031930 /UG=Hs.32916 nascent-polypeptide-associated complex alpha polypeptide /FL=gb:AF054187.1 gb:NM_005594.1" NM_005594 nascent polypeptide-associated complex alpha subunit NACA 4666 NM_001113201 /// NM_001113202 /// NM_001113203 /// NM_005594 /// NR_045277 /// XM_006719412 /// XM_006719413 /// XM_006719414 /// XM_006719415 /// XM_006719416 /// XM_006719417 /// XM_006719418 /// XM_006719419 /// XM_006719420 /// XM_006719421 "0003231 // cardiac ventricle development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043403 // skeletal muscle tissue regeneration // inferred from sequence or structural similarity /// 0048633 // positive regulation of skeletal muscle tissue growth // inferred from sequence or structural similarity /// 0048742 // regulation of skeletal muscle fiber development // inferred from sequence or structural similarity /// 0061384 // heart trabecula morphogenesis // inferred from sequence or structural similarity /// 1901227 // negative regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 1901228 // positive regulation of transcription from RNA polymerase II promoter involved in heart development // inferred from sequence or structural similarity /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005854 // nascent polypeptide-associated complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from sequence or structural similarity 200736_s_at NM_000581 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000581.1 /DEF=Homo sapiens glutathione peroxidase 1 (GPX1), mRNA. /FEA=mRNA /GEN=GPX1 /PROD=glutathione peroxidase 1 /DB_XREF=gi:10834975 /UG=Hs.76686 glutathione peroxidase 1 /FL=gb:NM_000581.1 gb:BC000742.1 gb:M21304.1" NM_000581 glutathione peroxidase 1 GPX1 2876 NM_000581 /// NM_201397 "0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001659 // temperature homeostasis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006982 // response to lipid hydroperoxide // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0009609 // response to symbiotic bacterium // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from mutant phenotype /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0018158 // protein oxidation // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from mutant phenotype /// 0035094 // response to nicotine // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from direct assay /// 0042311 // vasodilation // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from mutant phenotype /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0051702 // interaction with symbiont // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060047 // heart contraction // inferred from mutant phenotype /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0043295 // glutathione binding // inferred from electronic annotation /// 0047066 // phospholipid-hydroperoxide glutathione peroxidase activity // inferred from electronic annotation 200737_at NM_000291 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000291.1 /DEF=Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA. /FEA=mRNA /GEN=PGK1 /PROD=phosphoglycerate kinase 1 /DB_XREF=gi:4505762 /UG=Hs.78771 phosphoglycerate kinase 1 /FL=gb:NM_000291.1" NM_000291 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // not recorded /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200738_s_at NM_000291 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000291.1 /DEF=Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA. /FEA=mRNA /GEN=PGK1 /PROD=phosphoglycerate kinase 1 /DB_XREF=gi:4505762 /UG=Hs.78771 phosphoglycerate kinase 1 /FL=gb:NM_000291.1" NM_000291 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // not recorded /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200739_s_at BG338532 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG338532 /FEA=EST /DB_XREF=gi:13144970 /DB_XREF=est:602436260F1 /CLONE=IMAGE:4554278 /UG=Hs.85119 SMT3 (suppressor of mif two 3, yeast) homolog 1 /FL=gb:BC000036.1 gb:NM_006936.1" BG338532 small ubiquitin-like modifier 3 SUMO3 6612 NM_001286416 /// NM_006936 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019789 // SUMO ligase activity // inferred from electronic annotation 200740_s_at NM_006936 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006936.1 /DEF=Homo sapiens SMT3 (suppressor of mif two 3, yeast) homolog 1 (SMT3H1), mRNA. /FEA=mRNA /GEN=SMT3H1 /PROD=SMT3 (suppressor of mif two 3, yeast) homolog 1 /DB_XREF=gi:5902095 /UG=Hs.85119 SMT3 (suppressor of mif two 3, yeast) homolog 1 /FL=gb:BC000036.1 gb:NM_006936.1" NM_006936 small ubiquitin-like modifier 3 SUMO3 6612 NM_001286416 /// NM_006936 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // traceable author statement /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019789 // SUMO ligase activity // inferred from electronic annotation 200741_s_at NM_001030 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001030.1 /DEF=Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA. /FEA=mRNA /GEN=RPS27 /PROD=ribosomal protein S27 (metallopanstimulin 1) /DB_XREF=gi:4506710 /UG=Hs.195453 ribosomal protein S27 (metallopanstimulin 1) /FL=gb:U57847.1 gb:L19739.1 gb:NM_001030.1" NM_001030 ribosomal protein S27 RPS27 6232 NM_001030 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200742_s_at BG231932 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG231932 /FEA=EST /DB_XREF=gi:12727071 /DB_XREF=est:naf34b12.x1 /CLONE=IMAGE:4142926 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) /FL=gb:AF017456.1 gb:NM_000391.2" BG231932 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 200743_s_at NM_000391 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000391.2 /DEF=Homo sapiens ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) (CLN2), mRNA. /FEA=mRNA /GEN=CLN2 /PROD=ceroid-lipofuscinosis, neuronal 2, lateinfantile (Jansky-Bielschowsky disease) /DB_XREF=gi:5597012 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) /FL=gb:AF017456.1 gb:NM_000391.2" NM_000391 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030163 // protein catabolic process // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 200744_s_at AI741124 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI741124 /FEA=EST /DB_XREF=gi:5109412 /DB_XREF=est:wg19c04.x1 /CLONE=IMAGE:2365542 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1" AI741124 "guanine nucleotide binding protein (G protein), beta polypeptide 1" GNB1 2782 NM_001282538 /// NM_001282539 /// NM_002074 "0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity" 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200745_s_at AF070603 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF070603.1 /DEF=Homo sapiens clone 24584 beta-subunit signal transducing proteins GSGI mRNA, partial cds. /FEA=mRNA /PROD=beta-subunit signal transducing proteins GSGI /DB_XREF=gi:3387983 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1" AF070603 "guanine nucleotide binding protein (G protein), beta polypeptide 1" GNB1 2782 NM_001282538 /// NM_001282539 /// NM_002074 "0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity" 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200746_s_at NM_002074 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002074.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1), mRNA. /FEA=mRNA /GEN=GNB1 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 1 /DB_XREF=gi:11321584 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1" NM_002074 "guanine nucleotide binding protein (G protein), beta polypeptide 1" GNB1 2782 NM_001282538 /// NM_001282539 /// NM_002074 "0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010659 // cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity" 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097381 // photoreceptor disc membrane // traceable author statement 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200747_s_at NM_006185 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006185.1 /DEF=Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), mRNA. /FEA=mRNA /GEN=NUMA1 /PROD=nuclear mitotic apparatus protein 1 /DB_XREF=gi:5453819 /UG=Hs.301512 nuclear mitotic apparatus protein 1 /FL=gb:NM_006185.1" NM_006185 nuclear mitotic apparatus protein 1 NUMA1 4926 NM_001286561 /// NM_006185 /// NR_104476 /// XM_006718562 /// XM_006718563 /// XM_006718564 /// XM_006718565 /// XM_006718566 /// XM_006718567 /// XM_006718568 /// XM_006718569 /// XM_006718570 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006997 // nucleus organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0060487 // lung epithelial cell differentiation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation 200748_s_at NM_002032 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002032.1 /DEF=Homo sapiens ferritin, heavy polypeptide 1 (FTH1), mRNA. /FEA=mRNA /GEN=FTH1 /PROD=ferritin, heavy polypeptide 1 /DB_XREF=gi:4503794 /UG=Hs.62954 ferritin, heavy polypeptide 1 /FL=gb:BC000857.1 gb:BC001399.1 gb:M11146.1 gb:M12937.1 gb:M97164.1 gb:NM_002032.1 gb:L20941.1" NM_002032 "ferritin, heavy polypeptide 1" FTH1 2495 NM_002032 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006880 // intracellular sequestering of iron ion // inferred from direct assay /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006955 // immune response // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0008043 // intracellular ferritin complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004322 // ferroxidase activity // inferred from electronic annotation /// 0005506 // iron ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 200749_at BF112006 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF112006 /FEA=EST /DB_XREF=gi:10941619 /DB_XREF=est:7l37e05.x1 /CLONE=IMAGE:3523665 /UG=Hs.10842 RAN, member RAS oncogene family /FL=gb:BC000852.1 gb:BC004272.1 gb:M31469.1 gb:AF052578.1 gb:AF054183.1 gb:NM_006325.2" BF112006 "RAN, member RAS oncogene family" RAN 5901 NM_006325 /// XM_005253592 "0000055 // ribosomal large subunit export from nucleus // inferred from mutant phenotype /// 0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006405 // RNA export from nucleus // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0034629 // cellular protein complex localization // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement" 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // non-traceable author statement 200750_s_at AF054183 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF054183.1 /DEF=Homo sapiens GTP binding protein mRNA, complete cds. /FEA=mRNA /PROD=GTP binding protein /DB_XREF=gi:4092053 /UG=Hs.10842 RAN, member RAS oncogene family /FL=gb:BC000852.1 gb:BC004272.1 gb:M31469.1 gb:AF052578.1 gb:AF054183.1 gb:NM_006325.2" AF054183 "RAN, member RAS oncogene family" RAN 5901 NM_006325 /// XM_005253592 "0000055 // ribosomal large subunit export from nucleus // inferred from mutant phenotype /// 0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006405 // RNA export from nucleus // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0034629 // cellular protein complex localization // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0075733 // intracellular transport of virus // traceable author statement" 0000785 // chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // non-traceable author statement 200751_s_at BE898861 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE898861 /FEA=EST /DB_XREF=gi:10365758 /DB_XREF=est:601682157F1 /CLONE=IMAGE:3952046 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) /FL=gb:BC003394.1 gb:M16342.1 gb:NM_004500.1 BE898861 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 /// XM_006720124 /// XM_006720125 /// XM_006720126 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200752_s_at NM_005186 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005186.2 /DEF=Homo sapiens calpain 1, (muI) large subunit (CAPN1), mRNA. /FEA=mRNA /GEN=CAPN1 /PROD=calpain 1, large subunit /DB_XREF=gi:12408655 /UG=Hs.2575 calpain 1, (muI) large subunit /FL=gb:NM_005186.2" NM_005186 "calpain 1, (mu/I) large subunit" CAPN1 823 NM_001198868 /// NM_001198869 /// NM_005186 /// NR_040008 /// XM_006718698 0006508 // proteolysis // not recorded /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0032801 // receptor catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200753_x_at BE866585 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE866585 /FEA=EST /DB_XREF=gi:10315361 /DB_XREF=est:601678773F1 /CLONE=IMAGE:3961243 /UG=Hs.73965 splicing factor, arginineserine-rich 2 /FL=gb:BC000339.1 gb:BC001303.1 gb:M90104.1 gb:NM_003016.1" BE866585 microRNA 636 /// serine/arginine-rich splicing factor 2 MIR636 /// SRSF2 6427 /// 693221 NM_001195427 /// NM_003016 /// NR_030366 /// NR_036608 /// XR_429913 /// XR_429914 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // non-traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200754_x_at NM_003016 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003016.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 2 (SFRS2), mRNA. /FEA=mRNA /GEN=SFRS2 /PROD=splicing factor, arginineserine-rich 2 /DB_XREF=gi:4506898 /UG=Hs.73965 splicing factor, arginineserine-rich 2 /FL=gb:BC000339.1 gb:BC001303.1 gb:M90104.1 gb:NM_003016.1" NM_003016 microRNA 636 /// serine/arginine-rich splicing factor 2 MIR636 /// SRSF2 6427 /// 693221 NM_001195427 /// NM_003016 /// NR_030366 /// NR_036608 /// XR_429913 /// XR_429914 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // non-traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200755_s_at BF939365 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF939365 /FEA=EST /DB_XREF=gi:12356685 /DB_XREF=est:nad87h04.x1 /CLONE=IMAGE:3410551 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2 BF939365 calumenin CALU 813 NM_001130674 /// NM_001199671 /// NM_001199672 /// NM_001199673 /// NM_001199674 /// NM_001219 /// NR_074086 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200756_x_at U67280 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U67280.1 /DEF=Homo sapiens calumenin mRNA, complete cds. /FEA=mRNA /PROD=calumenin /DB_XREF=gi:2809323 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2" U67280 calumenin CALU 813 NM_001130674 /// NM_001199671 /// NM_001199672 /// NM_001199673 /// NM_001199674 /// NM_001219 /// NR_074086 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200757_s_at NM_001219 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001219.2 /DEF=Homo sapiens calumenin (CALU), mRNA. /FEA=mRNA /GEN=CALU /PROD=calumenin precursor /DB_XREF=gi:6005991 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2" NM_001219 calumenin CALU 813 NM_001130674 /// NM_001199671 /// NM_001199672 /// NM_001199673 /// NM_001199674 /// NM_001219 /// NR_074086 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200758_s_at AI361227 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI361227 /FEA=EST /DB_XREF=gi:4112848 /DB_XREF=est:qy12a07.x1 /CLONE=IMAGE:2011764 /UG=Hs.83469 nuclear factor (erythroid-derived 2)-like 1 /FL=gb:NM_003204.1 gb:U08853.1 AI361227 "nuclear factor, erythroid 2-like 1" NFE2L1 4779 NM_003204 /// XM_005257410 /// XM_005257411 /// XM_005257412 /// XM_005257413 /// XM_005257415 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200759_x_at NM_003204 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003204.1 /DEF=Homo sapiens nuclear factor (erythroid-derived 2)-like 1 (NFE2L1), mRNA. /FEA=mRNA /GEN=NFE2L1 /PROD=transcription factor 11 (basic leucine zippertype) /DB_XREF=gi:4505378 /UG=Hs.83469 nuclear factor (erythroid-derived 2)-like 1 /FL=gb:NM_003204.1 gb:U08853.1" NM_003204 "nuclear factor, erythroid 2-like 1" NFE2L1 4779 NM_003204 /// XM_005257410 /// XM_005257411 /// XM_005257412 /// XM_005257413 /// XM_005257415 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200760_s_at N92494 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N92494 /FEA=EST /DB_XREF=gi:1264803 /DB_XREF=est:zb12h11.s1 /CLONE=IMAGE:301893 /UG=Hs.92384 vitamin A responsive; cytoskeleton related /FL=gb:BC005143.1 gb:AF070523.1 gb:AF125530.1 gb:AF161476.1 gb:NM_006407.2 N92494 ADP-ribosylation factor-like 6 interacting protein 5 ARL6IP5 10550 NM_006407 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051051 // negative regulation of transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation 200761_s_at NM_006407 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006407.2 /DEF=Homo sapiens vitamin A responsive; cytoskeleton related (JWA), mRNA. /FEA=mRNA /GEN=JWA /PROD=vitamin A responsive; cytoskeleton related /DB_XREF=gi:7669496 /UG=Hs.92384 vitamin A responsive; cytoskeleton related /FL=gb:BC005143.1 gb:AF070523.1 gb:AF125530.1 gb:AF161476.1 gb:NM_006407.2" NM_006407 ADP-ribosylation factor-like 6 interacting protein 5 ARL6IP5 10550 NM_006407 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051051 // negative regulation of transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation 200762_at NM_001386 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001386.1 /DEF=Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), mRNA. /FEA=mRNA /GEN=DPYSL2 /PROD=dihydropyrimidinase-like 2 /DB_XREF=gi:4503376 /UG=Hs.173381 dihydropyrimidinase-like 2 /FL=gb:U17279.1 gb:D78013.1 gb:U97105.1 gb:NM_001386.1" NM_001386 dihydropyrimidinase-like 2 DPYSL2 1808 NM_001197293 /// NM_001244604 /// NM_001386 0001975 // response to amphetamine // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004157 // dihydropyrimidinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation" 200763_s_at NM_001003 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001003.1 /DEF=Homo sapiens ribosomal protein, large, P1 (RPLP1), mRNA. /FEA=mRNA /GEN=RPLP1 /PROD=ribosomal protein, large, P1 /DB_XREF=gi:4506668 /UG=Hs.177592 ribosomal protein, large, P1 /FL=gb:BC003369.1 gb:M17886.1 gb:NM_001003.1" NM_001003 "ribosomal protein, large, P1" RPLP1 6176 NM_001003 /// NM_213725 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200764_s_at AI826881 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI826881 /FEA=EST /DB_XREF=gi:5447552 /DB_XREF=est:wk75f03.x1 /CLONE=IMAGE:2421245 /UG=Hs.178452 catenin (cadherin-associated protein), alpha 1 (102kD) /FL=gb:L23805.1 gb:NM_001903.1" AI826881 "catenin (cadherin-associated protein), alpha 1, 102kDa" CTNNA1 1495 NM_001290307 /// NM_001290309 /// NM_001290310 /// NM_001290312 /// NM_001903 /// XM_005271898 /// XM_005271899 /// XM_006714536 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016264 // gap junction assembly // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from electronic annotation /// 2001045 // negative regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from electronic annotation 200765_x_at NM_001903 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001903.1 /DEF=Homo sapiens catenin (cadherin-associated protein), alpha 1 (102kD) (CTNNA1), mRNA. /FEA=mRNA /GEN=CTNNA1 /PROD=catenin (cadherin-associated protein), alpha 1(102kD) /DB_XREF=gi:4503126 /UG=Hs.178452 catenin (cadherin-associated protein), alpha 1 (102kD) /FL=gb:L23805.1 gb:NM_001903.1" NM_001903 "catenin (cadherin-associated protein), alpha 1, 102kDa" CTNNA1 1495 NM_001290307 /// NM_001290309 /// NM_001290310 /// NM_001290312 /// NM_001903 /// XM_005271898 /// XM_005271899 /// XM_006714536 0001541 // ovarian follicle development // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016264 // gap junction assembly // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation /// 0050808 // synapse organization // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from electronic annotation /// 2001045 // negative regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from electronic annotation 200766_at NM_001909 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001909.1 /DEF=Homo sapiens cathepsin D (lysosomal aspartyl protease) (CTSD), mRNA. /FEA=mRNA /GEN=CTSD /PROD=cathepsin D (lysosomal aspartyl protease) /DB_XREF=gi:4503142 /UG=Hs.79572 cathepsin D (lysosomal aspartyl protease) /FL=gb:M11233.1 gb:NM_001909.1" NM_001909 cathepsin D CTSD 1509 NM_001909 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200767_s_at NM_014612 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014612.1 /DEF=Homo sapiens C9orf10 protein (C9orf10), mRNA. /FEA=mRNA /GEN=C9orf10 /PROD=C9orf10 protein /DB_XREF=gi:8922113 /UG=Hs.76666 C9orf10 protein /FL=gb:AF214737.1 gb:NM_014612.1" NM_014612 family with sequence similarity 120A FAM120A 23196 NM_001286722 /// NM_001286723 /// NM_001286724 /// NM_014612 /// XM_005251842 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200768_s_at BC001686 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001686.1 /DEF=Homo sapiens, methionine adenosyltransferase II, alpha, clone MGC:2907, mRNA, complete cds. /FEA=mRNA /PROD=methionine adenosyltransferase II, alpha /DB_XREF=gi:12804546 /UG=Hs.77502 methionine adenosyltransferase II, alpha /FL=gb:BC001686.1 gb:BC001854.1 gb:NM_005911.1" BC001686 "methionine adenosyltransferase II, alpha" MAT2A 4144 NM_005911 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from direct assay /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0048269 // methionine adenosyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004478 // methionine adenosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200769_s_at NM_005911 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005911.1 /DEF=Homo sapiens methionine adenosyltransferase II, alpha (MAT2A), mRNA. /FEA=mRNA /GEN=MAT2A /PROD=methionine adenosyltransferase II, alpha /DB_XREF=gi:5174528 /UG=Hs.77502 methionine adenosyltransferase II, alpha /FL=gb:BC001686.1 gb:BC001854.1 gb:NM_005911.1" NM_005911 "methionine adenosyltransferase II, alpha" MAT2A 4144 NM_005911 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from direct assay /// 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0048269 // methionine adenosyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004478 // methionine adenosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200770_s_at J03202 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J03202.1 /DEF=Human laminin B2 chain mRNA, complete cds. /FEA=mRNA /GEN=LAMB2 /DB_XREF=gi:186916 /UG=Hs.214982 laminin, gamma 1 (formerly LAMB2) /FL=gb:J03202.1 gb:NM_002293.2" J03202 "laminin, gamma 1 (formerly LAMB2)" LAMC1 3915 NM_002293 0006461 // protein complex assembly // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007492 // endoderm development // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // non-traceable author statement /// 0005606 // laminin-1 complex // traceable author statement /// 0005615 // extracellular space // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043259 // laminin-10 complex // traceable author statement /// 0043260 // laminin-11 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 200771_at NM_002293 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002293.2 /DEF=Homo sapiens laminin, gamma 1 (formerly LAMB2) (LAMC1), mRNA. /FEA=mRNA /GEN=LAMC1 /PROD=laminin, gamma 1 precursor /DB_XREF=gi:9845497 /UG=Hs.214982 laminin, gamma 1 (formerly LAMB2) /FL=gb:J03202.1 gb:NM_002293.2" NM_002293 "laminin, gamma 1 (formerly LAMB2)" LAMC1 3915 NM_002293 0006461 // protein complex assembly // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007492 // endoderm development // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // non-traceable author statement /// 0005606 // laminin-1 complex // traceable author statement /// 0005615 // extracellular space // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043259 // laminin-10 complex // traceable author statement /// 0043260 // laminin-11 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 200772_x_at BF686442 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF686442 /FEA=EST /DB_XREF=gi:11971850 /DB_XREF=est:602143234F1 /CLONE=IMAGE:4304193 /UG=Hs.250655 prothymosin, alpha (gene sequence 28) /FL=gb:BC003510.1 gb:M26708.1 gb:M14630.1 gb:NM_002823.1" BF686442 "prothymosin alpha-like /// prothymosin alpha-like /// microRNA 1244-1 /// microRNA 1244-2 /// microRNA 1244-3 /// prothymosin, alpha" LOC100506248 /// LOC728026 /// MIR1244-1 /// MIR1244-2 /// MIR1244-3 /// PTMA 5757 /// 728026 /// 100302285 /// 100422872 /// 100422885 /// 100506248 NM_001099285 /// NM_002823 /// NR_036052 /// NR_036262 /// NR_036263 /// XM_001126659 /// XM_003960458 /// XM_005275719 /// XM_005276418 "0006351 // transcription, DNA-templated // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200773_x_at NM_002823 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002823.1 /DEF=Homo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA. /FEA=mRNA /GEN=PTMA /PROD=prothymosin, alpha (gene sequence 28) /DB_XREF=gi:4506276 /UG=Hs.250655 prothymosin, alpha (gene sequence 28) /FL=gb:BC003510.1 gb:M26708.1 gb:M14630.1 gb:NM_002823.1" NM_002823 "prothymosin, alpha" PTMA 5757 NM_001099285 /// NM_002823 "0006351 // transcription, DNA-templated // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200774_at BE963765 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE963765 /FEA=EST /DB_XREF=gi:11767182 /DB_XREF=est:601657412R1 /CLONE=IMAGE:3875738 /UG=Hs.76666 C9orf10 protein /FL=gb:AF214737.1 gb:NM_014612.1 BE963765 family with sequence similarity 120A FAM120A 23196 NM_001286722 /// NM_001286723 /// NM_001286724 /// NM_014612 /// XM_005251842 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200775_s_at BC000355 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000355.1 /DEF=Homo sapiens, heterogeneous nuclear ribonucleoprotein K, clone MGC:8660, mRNA, complete cds. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein K /DB_XREF=gi:12653174 /UG=Hs.129548 heterogeneous nuclear ribonucleoprotein K /FL=gb:BC000355.1 gb:NM_002140.1" BC000355 heterogeneous nuclear ribonucleoprotein K HNRNPK 3190 NM_002140 /// NM_031262 /// NM_031263 /// XM_005251960 /// XM_005251961 /// XM_005251963 /// XM_005251964 /// XM_005251965 /// XM_005251966 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0072369 // regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200776_s_at AL518328 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL518328 /FEA=EST /DB_XREF=gi:12781821 /DB_XREF=est:AL518328 /CLONE=CS0DA009YK18 (3 prime) /UG=Hs.155291 KIAA0005 gene product /FL=gb:D13630.1 gb:NM_014670.1 AL518328 basic leucine zipper and W2 domains 1 BZW1 9689 NM_001207067 /// NM_001207068 /// NM_001207069 /// NM_014670 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200777_s_at NM_014670 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014670.1 /DEF=Homo sapiens KIAA0005 gene product (KIAA0005), mRNA. /FEA=mRNA /GEN=KIAA0005 /PROD=KIAA0005 gene product /DB_XREF=gi:7661849 /UG=Hs.155291 KIAA0005 gene product /FL=gb:D13630.1 gb:NM_014670.1" NM_014670 basic leucine zipper and W2 domains 1 BZW1 9689 NM_001207067 /// NM_001207068 /// NM_001207069 /// NM_014670 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200778_s_at AI191427 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI191427 /FEA=EST /DB_XREF=gi:3742636 /DB_XREF=est:qe48g03.x1 /CLONE=IMAGE:1742260 /UG=Hs.155595 neural precursor cell expressed, developmentally down-regulated 5 /FL=gb:D28540.1 gb:NM_004404.1 gb:D63878.1" AI191427 septin 2 SEPT2 4735 NM_001008491 /// NM_001008492 /// NM_001282972 /// NM_001282973 /// NM_004404 /// NM_006155 /// XM_005247011 /// XM_005247012 /// XM_005247013 /// XM_006712546 /// XM_006712547 /// XM_006712548 /// XM_006712549 /// XM_006712550 0002036 // regulation of L-glutamate transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation "0000145 // exocyst // inferred from electronic annotation /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation 200779_at NM_001675 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001675.1 /DEF=Homo sapiens activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4), mRNA. /FEA=mRNA /GEN=ATF4 /PROD=activating transcription factor 4 /DB_XREF=gi:4502264 /UG=Hs.181243 activating transcription factor 4 (tax-responsive enhancer element B67) /FL=gb:M86842.1 gb:NM_001675.1" NM_001675 activating transcription factor 4 ATF4 468 NM_001675 /// NM_182810 "0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0043267 // negative regulation of potassium ion transport // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032590 // dendrite membrane // inferred from electronic annotation 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200780_x_at NM_000516 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000516.2 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1), mRNA. /FEA=mRNA /GEN=GNAS1 /PROD=guanine nucleotide binding protein (G protein),alpha stimulating activity polypeptide 1 /DB_XREF=gi:8659565 /UG=Hs.273385 guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 /FL=gb:BC002722.1 gb:AF088185.1 gb:NM_000516.2" NM_000516 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 200781_s_at NM_001019 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001019.1 /DEF=Homo sapiens ribosomal protein S15a (RPS15A), mRNA. /FEA=mRNA /GEN=RPS15A /PROD=ribosomal protein S15a /DB_XREF=gi:4506688 /UG=Hs.2953 ribosomal protein S15a /FL=gb:BC001697.1 gb:NM_001019.1" NM_001019 ribosomal protein S15a RPS15A 6210 NM_001019 /// NM_001030009 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from direct assay" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200782_at NM_001154 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001154.2 /DEF=Homo sapiens annexin A5 (ANXA5), mRNA. /FEA=mRNA /GEN=ANXA5 /PROD=annexin V /DB_XREF=gi:4809273 /UG=Hs.300711 annexin A5 /FL=gb:BC001429.1 gb:BC004993.1 gb:M18366.1 gb:J03745.1 gb:M21731.1 gb:M19384.1 gb:D00172.1 gb:NM_001154.2" NM_001154 annexin A5 ANXA5 308 NM_001154 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072563 // endothelial microparticle // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay 200783_s_at NM_005563 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005563.2 /DEF=Homo sapiens leukemia-associated phosphoprotein p18 (stathmin) (LAP18), mRNA. /FEA=mRNA /GEN=LAP18 /PROD=leukemia-associated phosphoprotein p18 /DB_XREF=gi:13518023 /UG=Hs.81915 leukemia-associated phosphoprotein p18 (stathmin) /FL=gb:NM_005563.2 gb:J04991.1" NM_005563 stathmin 1 STMN1 3925 NM_001145454 /// NM_005563 /// NM_152497 /// NM_203399 /// NM_203401 0007019 // microtubule depolymerization // inferred from direct assay /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0015631 // tubulin binding // inferred from direct assay 200784_s_at BF304759 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF304759 /FEA=EST /DB_XREF=gi:11251657 /DB_XREF=est:601888339F1 /CLONE=IMAGE:4122417 /UG=Hs.89137 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /FL=gb:NM_002332.1 BF304759 low density lipoprotein receptor-related protein 1 LRP1 4035 NM_002332 "0001523 // retinoid metabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from sequence or structural similarity /// 0014912 // negative regulation of smooth muscle cell migration // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032370 // positive regulation of lipid transport // inferred from sequence or structural similarity /// 0032374 // regulation of cholesterol transport // inferred from sequence or structural similarity /// 0032429 // regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042953 // lipoprotein transport // non-traceable author statement /// 0043277 // apoptotic cell clearance // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0051222 // positive regulation of protein transport // inferred from electronic annotation /// 0097242 // beta-amyloid clearance // traceable author statement /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0042954 // lipoprotein transporter activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070325 // lipoprotein particle receptor binding // inferred by curator 200785_s_at NM_002332 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002332.1 /DEF=Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (LRP1), mRNA. /FEA=mRNA /GEN=LRP1 /PROD=low density lipoprotein-related protein 1(alpha-2-macroglobulin receptor) /DB_XREF=gi:4758685 /UG=Hs.89137 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /FL=gb:NM_002332.1" NM_002332 low density lipoprotein receptor-related protein 1 LRP1 4035 NM_002332 "0001523 // retinoid metabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010875 // positive regulation of cholesterol efflux // inferred from sequence or structural similarity /// 0014912 // negative regulation of smooth muscle cell migration // inferred from sequence or structural similarity /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0032370 // positive regulation of lipid transport // inferred from sequence or structural similarity /// 0032374 // regulation of cholesterol transport // inferred from sequence or structural similarity /// 0032429 // regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0042953 // lipoprotein transport // non-traceable author statement /// 0043277 // apoptotic cell clearance // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0051222 // positive regulation of protein transport // inferred from electronic annotation /// 0097242 // beta-amyloid clearance // traceable author statement /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0042954 // lipoprotein transporter activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070325 // lipoprotein particle receptor binding // inferred by curator 200786_at NM_002799 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002799.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7), mRNA. /FEA=mRNA /GEN=PSMB7 /PROD=proteasome (prosome, macropain) subunit, betatype, 7 /DB_XREF=gi:4506202 /UG=Hs.118065 proteasome (prosome, macropain) subunit, beta type, 7 /FL=gb:BC000509.1 gb:D38048.1 gb:NM_002799.1" NM_002799 "proteasome (prosome, macropain) subunit, beta type, 7" PSMB7 5695 NM_002799 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200787_s_at BC002426 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002426.1 /DEF=Homo sapiens, phosphoprotein enriched in astrocytes 15, clone MGC:1685, mRNA, complete cds. /FEA=mRNA /PROD=phosphoprotein enriched in astrocytes 15 /DB_XREF=gi:12803230 /UG=Hs.194673 phosphoprotein enriched in astrocytes 15 /FL=gb:BC002426.1 gb:NM_003768.1" BC002426 phosphoprotein enriched in astrocytes 15 PEA15 8682 NM_003768 /// XM_005245564 /// XM_006711598 /// XM_006711599 0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 200788_s_at NM_003768 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003768.1 /DEF=Homo sapiens phosphoprotein enriched in astrocytes 15 (PEA15), mRNA. /FEA=mRNA /GEN=PEA15 /PROD=phosphoprotein enriched in astrocytes 15 /DB_XREF=gi:4505704 /UG=Hs.194673 phosphoprotein enriched in astrocytes 15 /FL=gb:BC002426.1 gb:NM_003768.1" NM_003768 phosphoprotein enriched in astrocytes 15 PEA15 8682 NM_003768 /// XM_005245564 /// XM_006711598 /// XM_006711599 0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 200789_at NM_001398 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001398.1 /DEF=Homo sapiens enoyl Coenzyme A hydratase 1, peroxisomal (ECH1), mRNA. /FEA=mRNA /GEN=ECH1 /PROD=peroxisomal enoyl-coenzyme A hydratase-likeprotein /DB_XREF=gi:4503446 /UG=Hs.196176 enoyl Coenzyme A hydratase 1, peroxisomal /FL=gb:NM_001398.1 gb:U16660.1" NM_001398 "enoyl CoA hydratase 1, peroxisomal" ECH1 1891 NM_001398 /// XM_005258610 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 200790_at NM_002539 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:NM_002539.1 /DEF=Homo sapiens ornithine decarboxylase 1 (ODC1) mRNA. /FEA=mRNA /GEN=ODC1 /PROD=ornithine decarboxylase 1 /DB_XREF=gi:4505488 /UG=Hs.75212 ornithine decarboxylase 1 /FL=gb:M16650.1 gb:NM_002539.1 NM_002539 ornithine decarboxylase 1 ODC1 4953 NM_001287188 /// NM_001287189 /// NM_001287190 /// NM_002539 0001822 // kidney development // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006596 // polyamine biosynthetic process // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009446 // putrescine biosynthetic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0033387 // putrescine biosynthetic process from ornithine // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004586 // ornithine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity 200791_s_at NM_003870 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003870.1 /DEF=Homo sapiens IQ motif containing GTPase activating protein 1 (IQGAP1), mRNA. /FEA=mRNA /GEN=IQGAP1 /PROD=IQ motif containing GTPase activating protein 1 /DB_XREF=gi:4506786 /UG=Hs.1742 IQ motif containing GTPase activating protein 1 /FL=gb:NM_003870.1 gb:L33075.1" NM_003870 IQ motif containing GTPase activating protein 1 IQGAP1 8826 NM_003870 /// XM_005254984 0001817 // regulation of cytokine production // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0035305 // negative regulation of dephosphorylation // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005884 // actin filament // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from electronic annotation" 200792_at NM_001469 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001469.1 /DEF=Homo sapiens thyroid autoantigen 70kD (Ku antigen) (G22P1), mRNA. /FEA=mRNA /GEN=G22P1 /PROD=thyroid autoantigen 70kD (Ku antigen) /DB_XREF=gi:4503840 /UG=Hs.197345 thyroid autoantigen 70kD (Ku antigen) /FL=gb:J04611.1 gb:M32865.1 gb:J04607.1 gb:NM_001469.1" NM_001469 X-ray repair complementing defective repair in Chinese hamster cells 6 XRCC6 2547 NM_001288976 /// NM_001288977 /// NM_001288978 /// NM_001469 "0000723 // telomere maintenance // traceable author statement /// 0006266 // DNA ligation // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from mutant phenotype /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation /// 0071475 // cellular hyperosmotic salinity response // inferred from electronic annotation /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0075713 // establishment of integrated proviral latency // traceable author statement" 0000783 // nuclear telomere cap complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0043564 // Ku70:Ku80 complex // inferred from direct assay /// 0070419 // nonhomologous end joining complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0042162 // telomeric DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from mutant phenotype 200793_s_at NM_001098 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001098.1 /DEF=Homo sapiens aconitase 2, mitochondrial (ACO2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACO2 /PROD=aconitase 2 /DB_XREF=gi:4501866 /UG=Hs.300463 aconitase 2, mitochondrial /FL=gb:U80040.1 gb:NM_001098.1" NM_001098 "aconitase 2, mitochondrial" ACO2 50 NM_001098 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006101 // citrate metabolic process // inferred from direct assay /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement "0003994 // aconitate hydratase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051538 // 3 iron, 4 sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation" 200794_x_at NM_014764 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014764.1 /DEF=Homo sapiens DAZ associated protein 2 (DAZAP2), mRNA. /FEA=mRNA /GEN=DAZAP2 /PROD=DAZ associated protein 2 /DB_XREF=gi:7661885 /UG=Hs.75416 DAZ associated protein 2 /FL=gb:BC002334.1 gb:D31767.1 gb:NM_014764.1" NM_014764 DAZ associated protein 2 DAZAP2 9802 NM_001136264 /// NM_001136266 /// NM_001136267 /// NM_001136268 /// NM_001136269 /// NM_014764 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 200795_at NM_004684 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004684.1 /DEF=Homo sapiens SPARC-like 1 (mast9, hevin) (SPARCL1), mRNA. /FEA=mRNA /GEN=SPARCL1 /PROD=SPARC-like 1 /DB_XREF=gi:4758521 /UG=Hs.75445 SPARC-like 1 (mast9, hevin) /FL=gb:NM_004684.1" NM_004684 SPARC-like 1 (hevin) SPARCL1 8404 NM_001128310 /// NM_001291976 /// NM_001291977 /// NM_004684 0007165 // signal transduction // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200796_s_at BF594446 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF594446 /FEA=EST /DB_XREF=gi:11686770 /DB_XREF=est:7i06c12.x1 /CLONE=IMAGE:3324694 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 BF594446 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 200797_s_at AI275690 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI275690 /FEA=EST /DB_XREF=gi:3897964 /DB_XREF=est:qw03a03.x1 /CLONE=IMAGE:1989964 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 AI275690 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 200798_x_at NM_021960 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021960.1 /DEF=Homo sapiens myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), mRNA. /FEA=mRNA /GEN=MCL1 /PROD=myeloid cell leukemia sequence 1 (BCL2-related) /DB_XREF=gi:11386164 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1" NM_021960 myeloid cell leukemia 1 MCL1 4170 NM_001197320 /// NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0071806 // protein transmembrane transport // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 1900118 // negative regulation of execution phase of apoptosis // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097136 // Bcl-2 family protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0042803 // protein homodimerization activity // not recorded /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction 200799_at NM_005345 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005345.3 /DEF=Homo sapiens heat shock 70kD protein 1A (HSPA1A), mRNA. /FEA=mRNA /GEN=HSPA1A /PROD=heat shock 70kD protein 1A /DB_XREF=gi:5579469 /UG=Hs.8997 heat shock 70kD protein 1A /FL=gb:BC002453.1 gb:NM_005345.3" NM_005345 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B HSPA1A /// HSPA1B 3303 /// 3304 NM_005345 /// NM_005346 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070370 // cellular heat acclimation // inferred from mutant phenotype /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0001618 // virus receptor activity // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0044183 // protein binding involved in protein folding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement" 200800_s_at NM_005345 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005345.3 /DEF=Homo sapiens heat shock 70kD protein 1A (HSPA1A), mRNA. /FEA=mRNA /GEN=HSPA1A /PROD=heat shock 70kD protein 1A /DB_XREF=gi:5579469 /UG=Hs.8997 heat shock 70kD protein 1A /FL=gb:BC002453.1 gb:NM_005345.3" NM_005345 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B /// heat shock 70kDa protein 1-like HSPA1A /// HSPA1B /// HSPA1L 3303 /// 3304 /// 3305 NM_005345 /// NM_005346 /// NM_005527 /// XM_005249070 /// XM_005249071 /// XM_005249073 /// XM_005272813 /// XM_005272816 /// XM_005272817 /// XM_005274859 /// XM_005274861 /// XM_005274862 /// XM_005274970 /// XM_005274973 /// XM_005274974 /// XM_005275399 /// XM_005275401 /// XM_005275402 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0006986 // response to unfolded protein // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070370 // cellular heat acclimation // inferred from mutant phenotype /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0001618 // virus receptor activity // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0044183 // protein binding involved in protein folding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement" 200801_x_at NM_001101 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001101.2 /DEF=Homo sapiens actin, beta (ACTB), mRNA. /FEA=mRNA /GEN=ACTB /PROD=beta actin /DB_XREF=gi:5016088 /UG=Hs.288061 actin, beta /FL=gb:BC001301.1 gb:BC002409.1 gb:BC004251.1 gb:NM_001101.2" NM_001101 "actin, beta" ACTB 60 NM_001101 /// XM_006715764 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 200802_at NM_006513 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006513.1 /DEF=Homo sapiens seryl-tRNA synthetase (SARS), mRNA. /FEA=mRNA /GEN=SARS /PROD=seryl-tRNA synthetase /DB_XREF=gi:5730028 /UG=Hs.4888 seryl-tRNA synthetase /FL=gb:BC000716.1 gb:NM_006513.1 gb:D49914.1" NM_006513 seryl-tRNA synthetase SARS 6301 NM_006513 /// NR_034072 /// NR_034073 /// XM_006710813 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0008033 // tRNA processing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0097056 // selenocysteinyl-tRNA(Sec) biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004828 // serine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200803_s_at AF033095 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF033095.1 /DEF=Homo sapiens testis enhanced gene transcript protein (TEGT) mRNA, complete cds. /FEA=mRNA /GEN=TEGT /PROD=testis enhanced gene transcript protein /DB_XREF=gi:2645728 /UG=Hs.74637 testis enhanced gene transcript (BAX inhibitor 1) /FL=gb:BC000916.1 gb:AF033095.1 gb:NM_003217.1" AF033095 transmembrane BAX inhibitor motif containing 6 TMBIM6 7009 NM_001098576 /// NM_003217 /// XM_005269126 0006915 // apoptotic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200804_at NM_003217 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003217.1 /DEF=Homo sapiens testis enhanced gene transcript (TEGT), mRNA. /FEA=mRNA /GEN=TEGT /PROD=testis enhanced gene transcript /DB_XREF=gi:4507432 /UG=Hs.74637 testis enhanced gene transcript (BAX inhibitor 1) /FL=gb:BC000916.1 gb:AF033095.1 gb:NM_003217.1" NM_003217 transmembrane BAX inhibitor motif containing 6 TMBIM6 7009 NM_001098576 /// NM_003217 /// XM_005269126 0006915 // apoptotic process // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200805_at NM_006816 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006816.1 /DEF=Homo sapiens endoplasmic reticulum glycoprotein (GP36B), mRNA. /FEA=mRNA /GEN=GP36B /PROD=endoplasmic reticulum glycoprotein /DB_XREF=gi:5803022 /UG=Hs.75864 endoplasmic reticulum glycoprotein /FL=gb:U10362.1 gb:NM_006816.1" NM_006816 "lectin, mannose-binding 2" LMAN2 10960 NM_006816 "0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from mutant phenotype" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from mutant phenotype /// 0030246 // carbohydrate binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200806_s_at BE256479 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE256479 /FEA=EST /DB_XREF=gi:9126938 /DB_XREF=est:601111293F1 /CLONE=IMAGE:3352031 /UG=Hs.79037 heat shock 60kD protein 1 (chaperonin) /FL=gb:BC002676.1 gb:BC003030.1 gb:M34664.1 gb:M22382.1 gb:NM_002156.1 BE256479 heat shock 60kDa protein 1 (chaperonin) HSPD1 3329 NM_002156 /// NM_199440 /// XM_005246518 0002368 // B cell cytokine production // inferred from direct assay /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from direct assay /// 0002842 // positive regulation of T cell mediated immune response to tumor cell // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006458 // 'de novo' protein folding // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042113 // B cell activation // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048291 // isotype switching to IgG isotypes // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051131 // chaperone-mediated protein complex assembly // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0030135 // coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003688 // DNA replication origin binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred by curator /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 200807_s_at NM_002156 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002156.1 /DEF=Homo sapiens heat shock 60kD protein 1 (chaperonin) (HSPD1), mRNA. /FEA=mRNA /GEN=HSPD1 /PROD=heat shock 60kD protein 1 (chaperonin) /DB_XREF=gi:4504520 /UG=Hs.79037 heat shock 60kD protein 1 (chaperonin) /FL=gb:BC002676.1 gb:BC003030.1 gb:M34664.1 gb:M22382.1 gb:NM_002156.1" NM_002156 heat shock 60kDa protein 1 (chaperonin) HSPD1 3329 NM_002156 /// NM_199440 /// XM_005246518 0002368 // B cell cytokine production // inferred from direct assay /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from direct assay /// 0002842 // positive regulation of T cell mediated immune response to tumor cell // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006458 // 'de novo' protein folding // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0042113 // B cell activation // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048291 // isotype switching to IgG isotypes // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051131 // chaperone-mediated protein complex assembly // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0030135 // coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003688 // DNA replication origin binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred by curator /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 200808_s_at NM_003461 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003461.1 /DEF=Homo sapiens zyxin (ZYX), mRNA. /FEA=mRNA /GEN=ZYX /PROD=zyxin /DB_XREF=gi:4508046 /UG=Hs.75873 zyxin /FL=gb:NM_003461.1" NM_003461 zyxin ZYX 7791 NM_001010972 /// NM_003461 /// XM_005250052 /// XM_005250053 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200809_x_at NM_000976 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000976.1 /DEF=Homo sapiens ribosomal protein L12 (RPL12), mRNA. /FEA=mRNA /GEN=RPL12 /PROD=ribosomal protein L12 /DB_XREF=gi:4506596 /UG=Hs.182979 ribosomal protein L12 /FL=gb:L06505.1 gb:NM_000976.1" NM_000976 ribosomal protein L12 RPL12 6136 NM_000976 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200810_s_at NM_001280 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001280.1 /DEF=Homo sapiens cold inducible RNA-binding protein (CIRBP), mRNA. /FEA=mRNA /GEN=CIRBP /PROD=cold inducible RNA-binding protein /DB_XREF=gi:4502846 /UG=Hs.119475 cold inducible RNA-binding protein /FL=gb:D78134.1 gb:BC000403.1 gb:BC000901.1 gb:AF021336.1 gb:NM_001280.1" NM_001280 cold inducible RNA binding protein CIRBP 1153 NM_001280 /// NR_023312 /// NR_023313 /// XM_006722636 /// XM_006722637 /// XM_006722638 /// XR_430127 /// XR_430128 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0034063 // stress granule assembly // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030371 // translation repressor activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070181 // small ribosomal subunit rRNA binding // inferred from direct assay 200811_at NM_001280 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001280.1 /DEF=Homo sapiens cold inducible RNA-binding protein (CIRBP), mRNA. /FEA=mRNA /GEN=CIRBP /PROD=cold inducible RNA-binding protein /DB_XREF=gi:4502846 /UG=Hs.119475 cold inducible RNA-binding protein /FL=gb:D78134.1 gb:BC000403.1 gb:BC000901.1 gb:AF021336.1 gb:NM_001280.1" NM_001280 cold inducible RNA binding protein CIRBP 1153 NM_001280 /// NR_023312 /// NR_023313 /// XM_006722636 /// XM_006722637 /// XM_006722638 /// XR_430127 /// XR_430128 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0034063 // stress granule assembly // inferred from sequence or structural similarity /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030371 // translation repressor activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070181 // small ribosomal subunit rRNA binding // inferred from direct assay 200812_at NM_006429 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006429.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 7 (eta) (CCT7), mRNA. /FEA=mRNA /GEN=CCT7 /PROD=chaperonin containing TCP1, subunit 7 (eta) /DB_XREF=gi:5453606 /UG=Hs.108809 chaperonin containing TCP1, subunit 7 (eta) /FL=gb:AF026292.1 gb:NM_006429.1" NM_006429 "chaperonin containing TCP1, subunit 7 (eta)" CCT7 10574 NM_001009570 /// NM_001166284 /// NM_001166285 /// NM_006429 /// NR_029402 /// NR_029403 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 200813_s_at BE256969 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE256969 /FEA=EST /DB_XREF=gi:9127437 /DB_XREF=est:601112157F1 /CLONE=IMAGE:3352623 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2" BE256969 "platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)" PAFAH1B1 5048 NM_000430 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001675 // acrosome assembly // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0036035 // osteoclast development // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051660 // establishment of centrosome localization // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200814_at NM_006263 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006263.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (PSME1), mRNA. /FEA=mRNA /GEN=PSME1 /PROD=proteasome (prosome, macropain) activatorsubunit 1 (PA28 alpha) /DB_XREF=gi:5453989 /UG=Hs.75348 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) /FL=gb:BC000352.1 gb:L07633.1 gb:NM_006263.1" NM_006263 "proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)" PSME1 5720 NM_001281528 /// NM_001281529 /// NM_006263 /// NM_176783 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019884 // antigen processing and presentation of exogenous antigen // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0061133 // endopeptidase activator activity // inferred from electronic annotation 200815_s_at L13386 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L13386.1 /DEF=Homo sapiens (clone 47) Miller-Dieker lissencephaly protein (LIS1) mRNA, complete cds. /FEA=mRNA /GEN=LIS1 /PROD=Miller-Dieker lissencephaly protein /DB_XREF=gi:349825 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2" L13386 "platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)" PAFAH1B1 5048 NM_000430 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001675 // acrosome assembly // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0036035 // osteoclast development // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051660 // establishment of centrosome localization // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200816_s_at NM_000430 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000430.2 /DEF=Homo sapiens platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) (PAFAH1B1), mRNA. /FEA=mRNA /GEN=PAFAH1B1 /PROD=platelet-activating factor acetylhydrolase,isoform Ib, alpha subunit (45kD) /DB_XREF=gi:6031206 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2" NM_000430 "platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)" PAFAH1B1 5048 NM_000430 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001675 // acrosome assembly // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0009306 // protein secretion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in cerebral cortex // inferred from sequence or structural similarity /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0036035 // osteoclast development // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from electronic annotation /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051081 // nuclear envelope disassembly // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051660 // establishment of centrosome localization // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0045505 // dynein intermediate chain binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200817_x_at NM_001014 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001014.1 /DEF=Homo sapiens ribosomal protein S10 (RPS10), mRNA. /FEA=mRNA /GEN=RPS10 /PROD=ribosomal protein S10 /DB_XREF=gi:4506678 /UG=Hs.76230 ribosomal protein S10 /FL=gb:BC001032.1 gb:BC001955.1 gb:BC005012.1 gb:NM_001014.1 gb:U14972.1" NM_001014 ribosomal protein S10 RPS10 6204 NM_001014 /// NM_001203245 /// NM_001204091 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200818_at NM_001697 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001697.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) (ATP5O), mRNA. /FEA=mRNA /GEN=ATP5O /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, O subunit (oligomycin sensitivity conferringprotein) /DB_XREF=gi:4502302 /UG=Hs.76572 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) /FL=gb:NM_001697.1" NM_001697 "ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit" ATP5O 539 NM_001697 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred from mutant phenotype /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005215 // transporter activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation" 200819_s_at NM_001018 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001018.1 /DEF=Homo sapiens ribosomal protein S15 (RPS15), mRNA. /FEA=mRNA /GEN=RPS15 /PROD=ribosomal protein S15 /DB_XREF=gi:4506686 /UG=Hs.133230 ribosomal protein S15 /FL=gb:J02984.1 gb:NM_001018.1" NM_001018 ribosomal protein S15 RPS15 6209 NM_001018 "0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200820_at NM_002812 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002812.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8), mRNA. /FEA=mRNA /GEN=PSMD8 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 8 /DB_XREF=gi:4506232 /UG=Hs.78466 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 /FL=gb:D38047.1 gb:BC001164.1 gb:NM_002812.1" NM_002812 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 8" PSMD8 5714 NM_002812 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200821_at NM_013995 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013995.1 /DEF=Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant LAMP2B, mRNA. /FEA=mRNA /GEN=LAMP2 /PROD=lysosomal-associated membrane protein 2precursor /DB_XREF=gi:7669502 /UG=Hs.8262 lysosomal-associated membrane protein 2 /FL=gb:U36336.1 gb:BC002965.1 gb:NM_013995.1" NM_013995 lysosomal-associated membrane protein 2 LAMP2 3920 NM_001122606 /// NM_002294 /// NM_013995 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019899 // enzyme binding // inferred from physical interaction 200822_x_at NM_000365 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000365.1 /DEF=Homo sapiens triosephosphate isomerase 1 (TPI1), mRNA. /FEA=mRNA /GEN=TPI1 /PROD=triosephosphate isomerase 1 /DB_XREF=gi:4507644 /UG=Hs.83848 triosephosphate isomerase 1 /FL=gb:BC004230.1 gb:NM_000365.1" NM_000365 triosephosphate isomerase 1 TPI1 7167 NM_000365 /// NM_001159287 /// NM_001258026 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0019682 // glyceraldehyde-3-phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004807 // triose-phosphate isomerase activity // not recorded /// 0004807 // triose-phosphate isomerase activity // non-traceable author statement /// 0004807 // triose-phosphate isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 200823_x_at NM_000992 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000992.1 /DEF=Homo sapiens ribosomal protein L29 (RPL29), mRNA. /FEA=mRNA /GEN=RPL29 /PROD=ribosomal protein L29 /DB_XREF=gi:4506628 /UG=Hs.183698 ribosomal protein L29 /FL=gb:U49083.1 gb:NM_000992.1 gb:U10248.1" NM_000992 ribosomal protein L29 RPL29 6159 NM_000992 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007566 // embryo implantation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200824_at NM_000852 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000852.2 /DEF=Homo sapiens glutathione S-transferase pi (GSTP1), mRNA. /FEA=mRNA /GEN=GSTP1 /PROD=glutathione transferase /DB_XREF=gi:6552334 /UG=Hs.226795 glutathione S-transferase pi /FL=gb:U62589.1 gb:U30897.1 gb:NM_000852.2" NM_000852 glutathione S-transferase pi 1 GSTP1 2950 NM_000852 0000302 // response to reactive oxygen species // inferred from sequence or structural similarity /// 0002674 // negative regulation of acute inflammatory response // non-traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009890 // negative regulation of biosynthetic process // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred by curator /// 0032691 // negative regulation of interleukin-1 beta production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0032930 // positive regulation of superoxide anion generation // inferred from sequence or structural similarity /// 0035726 // common myeloid progenitor cell proliferation // inferred from sequence or structural similarity /// 0035732 // nitric oxide storage // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // non-traceable author statement /// 0043508 // negative regulation of JUN kinase activity // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0051771 // negative regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay /// 0060547 // negative regulation of necrotic cell death // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070664 // negative regulation of leukocyte proliferation // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097057 // TRAF2-GSTP1 complex // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008432 // JUN kinase binding // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0019207 // kinase regulator activity // inferred from sequence or structural similarity /// 0035730 // S-nitrosoglutathione binding // inferred from direct assay /// 0035731 // dinitrosyl-iron complex binding // inferred from direct assay /// 0070026 // nitric oxide binding // non-traceable author statement 200825_s_at NM_006389 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006389.2 /DEF=Homo sapiens oxygen regulated protein (150kD) (ORP150), mRNA. /FEA=mRNA /GEN=ORP150 /PROD=oxygen regulated protein precursor /DB_XREF=gi:13699861 /UG=Hs.277704 oxygen regulated protein (150kD) /FL=gb:NM_006389.2 gb:U65785.1" NM_006389 hypoxia up-regulated 1 HYOU1 10525 NM_001130991 /// NM_006389 /// XM_005271390 /// XM_005271392 /// XM_005271393 /// XM_005271394 0002931 // response to ischemia // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200826_at NM_004597 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004597.3 /DEF=Homo sapiens small nuclear ribonucleoprotein D2 polypeptide (16.5kD) (SNRPD2), mRNA. /FEA=mRNA /GEN=SNRPD2 /PROD=small nuclear ribonucleoprotein D2 polypeptide(16.5kD) /DB_XREF=gi:7242206 /UG=Hs.53125 small nuclear ribonucleoprotein D2 polypeptide (16.5kD) /FL=gb:BC000486.1 gb:BC001930.1 gb:U15008.1 gb:NM_004597.3" NM_004597 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa SNRPD2 6633 NM_004597 /// NM_177542 /// XM_005259180 "0000245 // spliceosomal complex assembly // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200827_at NM_000302 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000302.1 /DEF=Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) (PLOD), mRNA. /FEA=mRNA /GEN=PLOD /PROD=procollagen-lysine 5-dioxygenase /DB_XREF=gi:4557836 /UG=Hs.75093 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) /FL=gb:L06419.1 gb:NM_000302.1" NM_000302 "procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1" PLOD1 5351 NM_000302 0001666 // response to hypoxia // inferred from expression pattern /// 0006464 // cellular protein modification process // non-traceable author statement /// 0008544 // epidermis development // inferred from mutant phenotype /// 0008544 // epidermis development // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0046947 // hydroxylysine biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005506 // iron ion binding // inferred from electronic annotation /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 200828_s_at BE871379 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE871379 /FEA=EST /DB_XREF=gi:10320155 /DB_XREF=est:601449306F1 /CLONE=IMAGE:3853200 /UG=Hs.62112 zinc finger protein 207 /FL=gb:AF046001.1 gb:NM_003457.1 BE871379 zinc finger protein 207 ZNF207 7756 NM_001032293 /// NM_001098507 /// NM_003457 /// XM_005258028 /// XM_005258029 /// XM_005258030 "0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000776 // kinetochore // inferred from mutant phenotype /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation" 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200829_x_at NM_003457 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003457.1 /DEF=Homo sapiens zinc finger protein 207 (ZNF207), mRNA. /FEA=mRNA /GEN=ZNF207 /PROD=zinc finger protein 207 /DB_XREF=gi:4508016 /UG=Hs.62112 zinc finger protein 207 /FL=gb:AF046001.1 gb:NM_003457.1" NM_003457 zinc finger protein 207 ZNF207 7756 NM_001032293 /// NM_001098507 /// NM_003457 /// XM_005258028 /// XM_005258029 /// XM_005258030 "0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051983 // regulation of chromosome segregation // inferred from mutant phenotype" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000776 // kinetochore // inferred from mutant phenotype /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation" 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200830_at NM_002808 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002808.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (PSMD2), mRNA. /FEA=mRNA /GEN=PSMD2 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 2 /DB_XREF=gi:4506226 /UG=Hs.74619 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 /FL=gb:D78151.1 gb:BC002368.1 gb:BC002997.1 gb:NM_002808.1 gb:U18247.1 gb:U12596.1" NM_002808 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 2" PSMD2 5708 NM_001278708 /// NM_001278709 /// NM_002808 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation 200831_s_at AA678241 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA678241 /FEA=EST /DB_XREF=gi:2658763 /DB_XREF=est:zi27a06.s1 /CLONE=IMAGE:431986 /UG=Hs.119597 stearoyl-CoA desaturase (delta-9-desaturase) /FL=gb:AF097514.1 gb:NM_005063.1 gb:AB032261.1 AA678241 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation" 200832_s_at AB032261 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB032261.1 /DEF=Homo sapiens Scd mRNA for stearoyl-CoA desaturase, complete cds. /FEA=mRNA /GEN=Scd /PROD=stearoyl-CoA desaturase /DB_XREF=gi:7415720 /UG=Hs.119597 stearoyl-CoA desaturase (delta-9-desaturase) /FL=gb:AF097514.1 gb:NM_005063.1 gb:AB032261.1" AB032261 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation" 200833_s_at NM_015646 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015646.1 /DEF=Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), mRNA. /FEA=mRNA /GEN=RAP1B /PROD=DKFZP586H0723 protein /DB_XREF=gi:7661677 /UG=Hs.156764 RAP1B, member of RAS oncogene family /FL=gb:BC000176.2 gb:NM_015646.1" NM_015646 "RAP1B, member of RAS oncogene family" RAP1B 5908 NM_001010942 /// NM_001251917 /// NM_001251918 /// NM_001251921 /// NM_001251922 /// NM_015646 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from electronic annotation /// 0038180 // nerve growth factor signaling pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from electronic annotation /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype /// 2001214 // positive regulation of vasculogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from direct assay 200834_s_at NM_001024 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001024.1 /DEF=Homo sapiens ribosomal protein S21 (RPS21), mRNA. /FEA=mRNA /GEN=RPS21 /PROD=ribosomal protein S21 /DB_XREF=gi:4506698 /UG=Hs.1948 ribosomal protein S21 /FL=gb:L04483.1 gb:NM_001024.1" NM_001024 ribosomal protein S21 RPS21 6227 NM_001024 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000447 // endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0000461 // endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0042274 // ribosomal small subunit biogenesis // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 200835_s_at AI553791 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI553791 /FEA=EST /DB_XREF=gi:4486154 /DB_XREF=est:tn29a04.x1 /CLONE=IMAGE:2169006 /UG=Hs.239298 microtubule-associated protein 4 /FL=gb:M64571.1 gb:NM_002375.1 gb:U19727.1 AI553791 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200836_s_at NM_002375 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002375.1 /DEF=Homo sapiens microtubule-associated protein 4 (MAP4), mRNA. /FEA=mRNA /GEN=MAP4 /PROD=microtubule-associated protein 4 /DB_XREF=gi:4505098 /UG=Hs.239298 microtubule-associated protein 4 /FL=gb:M64571.1 gb:NM_002375.1 gb:U19727.1" NM_002375 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 /// XM_005265133 /// XM_005265134 /// XM_005265135 /// XM_005265138 /// XM_005265139 /// XM_005265147 /// XM_005265155 /// XM_005265157 /// XM_005265158 /// XM_005265159 /// XM_006713140 /// XM_006713141 /// XM_006713142 /// XM_006713143 /// XM_006713144 /// XM_006713145 /// XM_006713146 /// XM_006713147 /// XM_006713148 /// XM_006713149 /// XM_006713150 /// XM_006713151 /// XM_006713152 /// XM_006713153 /// XM_006713154 /// XM_006713155 /// XM_006713156 /// XM_006713157 /// XM_006713158 /// XM_006713159 /// XM_006713160 /// XM_006713161 /// XM_006713162 /// XM_006713163 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0051012 // microtubule sliding // inferred from mutant phenotype /// 0051294 // establishment of spindle orientation // inferred from genetic interaction /// 0051294 // establishment of spindle orientation // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200837_at NM_005745 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005745.3 /DEF=Homo sapiens accessory proteins BAP31BAP29 (DXS1357E), mRNA. /FEA=mRNA /GEN=DXS1357E /PROD=accessory proteins BAP31BAP29 /DB_XREF=gi:10047078 /UG=Hs.291904 accessory proteins BAP31BAP29 /FL=gb:NM_005745.3" NM_005745 B-cell receptor-associated protein 31 BCAP31 10134 NM_001139441 /// NM_001139457 /// NM_001256447 /// NM_005745 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200838_at NM_001908 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001908.1 /DEF=Homo sapiens cathepsin B (CTSB), mRNA. /FEA=mRNA /GEN=CTSB /PROD=cathepsin B /DB_XREF=gi:4503138 /UG=Hs.297939 cathepsin B /FL=gb:M14221.1 gb:L16510.1 gb:NM_001908.1" NM_001908 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 /// XM_006716244 /// XM_006716245 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005622 // intracellular // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 200839_s_at NM_001908 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001908.1 /DEF=Homo sapiens cathepsin B (CTSB), mRNA. /FEA=mRNA /GEN=CTSB /PROD=cathepsin B /DB_XREF=gi:4503138 /UG=Hs.297939 cathepsin B /FL=gb:M14221.1 gb:L16510.1 gb:NM_001908.1" NM_001908 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 /// XM_006716244 /// XM_006716245 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042981 // regulation of apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005622 // intracellular // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 200840_at NM_005548 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005548.1 /DEF=Homo sapiens lysyl-tRNA synthetase (KARS), mRNA. /FEA=mRNA /GEN=KARS /PROD=lysyl-tRNA synthetase /DB_XREF=gi:5031814 /UG=Hs.3100 lysyl-tRNA synthetase /FL=gb:BC004132.1 gb:D32053.1 gb:NM_005548.1" NM_005548 lysyl-tRNA synthetase KARS 3735 NM_001130089 /// NM_005548 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006430 // lysyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015966 // diadenosine tetraphosphate biosynthetic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from electronic annotation 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // inferred from direct assay /// 0004824 // lysine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200841_s_at AI142677 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI142677 /FEA=EST /DB_XREF=gi:3659036 /DB_XREF=est:ok33h03.s1 /CLONE=IMAGE:1509653 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 AI142677 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // traceable author statement /// 0004827 // proline-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0035613 // RNA stem-loop binding // inferred from direct assay" 200842_s_at AI475965 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI475965 /FEA=EST /DB_XREF=gi:4329010 /DB_XREF=est:tl96a09.x1 /CLONE=IMAGE:2154904 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 AI475965 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // traceable author statement /// 0004827 // proline-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0035613 // RNA stem-loop binding // inferred from direct assay" 200843_s_at NM_004446 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004446.1 /DEF=Homo sapiens glutamyl-prolyl-tRNA synthetase (EPRS), mRNA. /FEA=mRNA /GEN=EPRS /PROD=glutamyl-prolyl tRNA synthetase /DB_XREF=gi:4758293 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1" NM_004446 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0097452 // GAIT complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // traceable author statement /// 0004827 // proline-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0035613 // RNA stem-loop binding // inferred from direct assay" 200844_s_at BE869583 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE869583 /FEA=EST /DB_XREF=gi:10318463 /DB_XREF=est:601445695F1 /CLONE=IMAGE:3849815 /UG=Hs.120 anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) /FL=gb:D14662.1 gb:NM_004905.1" BE869583 peroxiredoxin 6 PRDX6 9588 NM_004905 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 200845_s_at NM_004905 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004905.1 /DEF=Homo sapiens anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) (KIAA0106), mRNA. /FEA=mRNA /GEN=KIAA0106 /PROD=anti-oxidant protein 2 (non-selenium glutathioneperoxidase, acidic calcium-independent phospholipase A2) /DB_XREF=gi:4758637 /UG=Hs.120 anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) /FL=gb:D14662.1 gb:NM_004905.1" NM_004905 peroxiredoxin 6 PRDX6 9588 NM_004905 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 200846_s_at NM_002708 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002708.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, alpha isoform (PPP1CA), mRNA. /FEA=mRNA /GEN=PPP1CA /PROD=protein phosphatase 1, catalytic subunit, alphaisoform /DB_XREF=gi:4506002 /UG=Hs.183994 protein phosphatase 1, catalytic subunit, alpha isoform /FL=gb:BC001888.1 gb:BC004482.1 gb:M63960.1 gb:NM_002708.1" NM_002708 "protein phosphatase 1, catalytic subunit, alpha isozyme" PPP1CA 5499 NM_001008709 /// NM_002708 /// NM_206873 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200847_s_at NM_016127 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016127.1 /DEF=Homo sapiens HSPC035 protein (LOC51669), mRNA. /FEA=mRNA /GEN=LOC51669 /PROD=HSPC035 protein /DB_XREF=gi:7706384 /UG=Hs.279921 HSPC035 protein /FL=gb:AF100748.1 gb:AF078855.1 gb:NM_016127.1" NM_016127 store-operated calcium entry-associated regulatory factor SARAF 51669 NM_001284239 /// NM_016127 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 2001256 // regulation of store-operated calcium entry // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from direct assay 200848_at AA479488 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA479488 /FEA=EST /DB_XREF=gi:2208044 /DB_XREF=est:zv21c09.s1 /CLONE=IMAGE:754288 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 AA479488 adenosylhomocysteinase-like 1 AHCYL1 10768 NM_001242673 /// NM_001242674 /// NM_001242675 /// NM_001242676 /// NM_006621 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0031440 // regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0032412 // regulation of ion transmembrane transporter activity // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation" 200849_s_at AI589266 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI589266 /FEA=EST /DB_XREF=gi:4598314 /DB_XREF=est:tr58c06.x2 /CLONE=IMAGE:2222506 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 AI589266 adenosylhomocysteinase-like 1 AHCYL1 10768 NM_001242673 /// NM_001242674 /// NM_001242675 /// NM_001242676 /// NM_006621 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0031440 // regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0032412 // regulation of ion transmembrane transporter activity // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation" 200850_s_at NM_006621 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006621.1 /DEF=Homo sapiens S-adenosylhomocysteine hydrolase-like 1 (AHCYL1), mRNA. /FEA=mRNA /GEN=AHCYL1 /PROD=S-adenosylhomocysteine hydrolase-like 1 /DB_XREF=gi:5729723 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1" NM_006621 adenosylhomocysteinase-like 1 AHCYL1 10768 NM_001242673 /// NM_001242674 /// NM_001242675 /// NM_001242676 /// NM_006621 0006378 // mRNA polyadenylation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation /// 0031440 // regulation of mRNA 3'-end processing // inferred from electronic annotation /// 0032412 // regulation of ion transmembrane transporter activity // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation" 200851_s_at NM_014761 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014761.1 /DEF=Homo sapiens KIAA0174 gene product (KIAA0174), mRNA. /FEA=mRNA /GEN=KIAA0174 /PROD=KIAA0174 gene product /DB_XREF=gi:7661971 /UG=Hs.75824 KIAA0174 gene product /FL=gb:D79996.1 gb:BC000430.1 gb:BC004359.1 gb:NM_014761.1" NM_014761 increased sodium tolerance 1 homolog (yeast) IST1 9798 NM_001270975 /// NM_001270976 /// NM_001270977 /// NM_001270978 /// NM_001270979 /// NM_014761 0000910 // cytokinesis // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008104 // protein localization // inferred from mutant phenotype /// 0009838 // abscission // inferred from direct assay /// 0009838 // abscission // inferred from mutant phenotype /// 0019076 // viral release from host cell // inferred from direct assay /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046745 // viral capsid secondary envelopment // inferred from direct assay /// 0048672 // positive regulation of collateral sprouting // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0090543 // Flemming body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0090541 // MIT domain binding // inferred from physical interaction 200852_x_at NM_005273 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005273.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2 (GNB2), mRNA. /FEA=mRNA /GEN=GNB2 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 2 /DB_XREF=gi:4885282 /UG=Hs.91299 guanine nucleotide binding protein (G protein), beta polypeptide 2 /FL=gb:M16538.1 gb:M36429.1 gb:NM_005273.1" NM_005273 "guanine nucleotide binding protein (G protein), beta polypeptide 2" GNB2 2783 NM_005273 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 200853_at NM_002106 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002106.1 /DEF=Homo sapiens H2A histone family, member Z (H2AFZ), mRNA. /FEA=mRNA /GEN=H2AFZ /PROD=H2A histone family, member Z /DB_XREF=gi:4504254 /UG=Hs.119192 H2A histone family, member Z /FL=gb:M37583.1 gb:NM_002106.1" NM_002106 "H2A histone family, member Z" H2AFZ 3015 NM_002106 /// XM_005262971 0006334 // nucleosome assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from mutant phenotype 0000786 // nucleosome // inferred from electronic annotation /// 0001740 // Barr body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 200854_at AB028970 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB028970.1 /DEF=Homo sapiens mRNA for KIAA1047 protein, partial cds. /FEA=mRNA /GEN=KIAA1047 /PROD=KIAA1047 protein /DB_XREF=gi:5689430 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1" AB028970 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator" 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200855_at AW771910 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW771910 /FEA=EST /DB_XREF=gi:7703971 /DB_XREF=est:hn66c11.x1 /CLONE=IMAGE:3032852 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 AW771910 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator" 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200856_x_at BF437948 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF437948 /FEA=EST /DB_XREF=gi:11450465 /DB_XREF=est:7q63b10.x1 /CLONE=IMAGE:3702882 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 BF437948 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator" 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200857_s_at NM_006311 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006311.1 /DEF=Homo sapiens nuclear receptor co-repressor 1 (NCOR1), mRNA. /FEA=mRNA /GEN=NCOR1 /PROD=nuclear receptor co-repressor 1 /DB_XREF=gi:5454137 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1" NM_006311 nuclear receptor corepressor 1 NCOR1 9611 NM_001190438 /// NM_001190440 /// NM_006311 /// XM_005256866 /// XM_005256867 /// XM_005256868 /// XM_005256871 /// XM_005256872 /// XM_005256873 /// XM_005256874 /// XM_005256875 /// XM_006721601 /// XM_006721602 /// XM_006721603 /// XM_006721604 /// XM_006721605 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0002361 // CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0051225 // spindle assembly // inferred from mutant phenotype /// 0060318 // definitive erythrocyte differentiation // inferred from electronic annotation /// 0072362 // regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 2000191 // regulation of fatty acid transport // inferred by curator" 0000118 // histone deacetylase complex // inferred from direct assay /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation 200858_s_at NM_001012 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001012.1 /DEF=Homo sapiens ribosomal protein S8 (RPS8), mRNA. /FEA=mRNA /GEN=RPS8 /PROD=ribosomal protein S8 /DB_XREF=gi:4506742 /UG=Hs.151604 ribosomal protein S8 /FL=gb:NM_001012.1" NM_001012 "ribosomal protein S8 /// small nucleolar RNA, C/D box 38B /// small nucleolar RNA, C/D box 55" RPS8 /// SNORD38B /// SNORD55 6202 /// 26811 /// 94163 NM_001012 /// NR_000015 /// NR_001457 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay 200859_x_at NM_001456 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001456.1 /DEF=Homo sapiens filamin A, alpha (actin-binding protein-280) (FLNA), mRNA. /FEA=mRNA /GEN=FLNA /PROD=filamin 1 (actin-binding protein-280) /DB_XREF=gi:4503744 /UG=Hs.195464 filamin A, alpha (actin-binding protein-280) /FL=gb:NM_001456.1" NM_001456 "filamin A, alpha" FLNA 2316 NM_001110556 /// NM_001456 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034329 // cell junction assembly // traceable author statement /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0043113 // receptor clustering // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045022 // early endosome to late endosome transport // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051220 // cytoplasmic sequestering of protein // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from direct assay /// 0090307 // spindle assembly involved in mitosis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred by curator /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031523 // Myb complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097440 // apical dendrite // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from direct assay /// 0031267 // small GTPase binding // inferred from direct assay /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0034988 // Fc-gamma receptor I complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 200860_s_at BC000779 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000779.1 /DEF=Homo sapiens, Similar to KIAA1007 protein, clone MGC:692, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA1007 protein /DB_XREF=gi:12653966 /UG=Hs.279949 KIAA1007 protein /FL=gb:BC000779.1 gb:AF110778.1 gb:NM_016284.1" BC000779 "CCR4-NOT transcription complex, subunit 1" CNOT1 23019 NM_001265612 /// NM_016284 /// NM_206999 /// NR_049763 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype" 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200861_at NM_016284 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016284.1 /DEF=Homo sapiens KIAA1007 protein (KIAA1007), mRNA. /FEA=mRNA /GEN=KIAA1007 /PROD=KIAA1007 protein /DB_XREF=gi:7706213 /UG=Hs.279949 KIAA1007 protein /FL=gb:BC000779.1 gb:AF110778.1 gb:NM_016284.1" NM_016284 "CCR4-NOT transcription complex, subunit 1" CNOT1 23019 NM_001265612 /// NM_016284 /// NM_206999 /// NR_049763 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010606 // positive regulation of cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from mutant phenotype /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype" 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030014 // CCR4-NOT complex // inferred from direct assay 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200862_at NM_014762 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014762.1 /DEF=Homo sapiens seladin-1 (KIAA0018), mRNA. /FEA=mRNA /GEN=KIAA0018 /PROD=seladin-1 /DB_XREF=gi:13375617 /UG=Hs.75616 seladin-1 /FL=gb:AF261758.1 gb:BC004375.1 gb:NM_014762.1" NM_014762 24-dehydrocholesterol reductase DHCR24 1718 NM_014762 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // inferred from sequence or structural similarity /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from expression pattern /// 0007050 // cell cycle arrest // non-traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009888 // tissue development // inferred from mutant phenotype /// 0016125 // sterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0031639 // plasminogen activation // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1901214 // regulation of neuron death // non-traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0008762 // UDP-N-acetylmuramate dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from physical interaction /// 0050614 // delta24-sterol reductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 200863_s_at AI215102 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI215102 /FEA=EST /DB_XREF=gi:3778703 /DB_XREF=est:qg69g05.x1 /CLONE=IMAGE:1840472 /UG=Hs.75618 RAB11A, member RAS oncogene family /FL=gb:AF000231.1 gb:NM_004663.1" AI215102 "RAB11A, member RAS oncogene family" RAB11A 8766 NM_001206836 /// NM_004663 0000910 // cytokinesis // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048227 // plasma membrane to endosome transport // non-traceable author statement /// 0051223 // regulation of protein transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019905 // syntaxin binding // non-traceable author statement 200864_s_at NM_004663 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004663.1 /DEF=Homo sapiens RAB11A, member RAS oncogene family (RAB11A), mRNA. /FEA=mRNA /GEN=RAB11A /PROD=RAB11A, member RAS oncogene family /DB_XREF=gi:4758983 /UG=Hs.75618 RAB11A, member RAS oncogene family /FL=gb:AF000231.1 gb:NM_004663.1" NM_004663 "RAB11A, member RAS oncogene family" RAB11A 8766 NM_001206836 /// NM_004663 0000910 // cytokinesis // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0032402 // melanosome transport // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048227 // plasma membrane to endosome transport // non-traceable author statement /// 0051223 // regulation of protein transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from sequence or structural similarity /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019905 // syntaxin binding // non-traceable author statement 200865_at AI001896 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI001896 /FEA=EST /DB_XREF=gi:3202367 /DB_XREF=est:ot42a05.s1 /CLONE=IMAGE:1619408 /UG=Hs.7811 eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) /FL=gb:BC000490.1 gb:U94855.1 gb:NM_003754.1" AI001896 "eukaryotic translation initiation factor 3, subunit F" EIF3F 8665 NM_003754 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200866_s_at M32221 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M32221.1 /DEF=Human saposin proteins A-D mRNA, complete cds. /FEA=mRNA /GEN=PSAP /DB_XREF=gi:337761 /UG=Hs.78575 prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) /FL=gb:NM_002778.1 gb:BC004275.1 gb:J03077.1 gb:D00422.1 gb:M60255.1 gb:M32221.1 gb:M60257.1 gb:M60258.1 gb:M81355.1" M32221 prosaposin PSAP 5660 NM_001042465 /// NM_001042466 /// NM_002778 0002576 // platelet degranulation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008289 // lipid binding // traceable author statement 200867_at AL031685 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL031685 /DEF=Human DNA sequence from clone RP5-963K23 on chromosome 20q13.11-13.2 Contains a KRT18 (Keratin type I, Cytoskeletal 18 (Cytokeratin 18, CK18,CYK18)) pseudogene, a gene for a novel protein, the gene for spermatogenesis associated protein PD1 (KIAA0... /FEA=mRNA_2 /DB_XREF=gi:9368423 /UG=Hs.10590 zinc finger protein 313 /FL=gb:AF265215.1 gb:NM_018683.1" AL031685 ring finger protein 114 RNF114 55905 NM_018683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200868_s_at NM_018683 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018683.1 /DEF=Homo sapiens zinc finger protein 313 (ZNF313), mRNA. /FEA=mRNA /GEN=ZNF313 /PROD=zinc finger protein 313 /DB_XREF=gi:8923897 /UG=Hs.10590 zinc finger protein 313 /FL=gb:AF265215.1 gb:NM_018683.1" NM_018683 ring finger protein 114 RNF114 55905 NM_018683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200869_at NM_000980 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000980.1 /DEF=Homo sapiens ribosomal protein L18a (RPL18A), mRNA. /FEA=mRNA /GEN=RPL18A /PROD=ribosomal protein L18a /DB_XREF=gi:11415025 /UG=Hs.163593 ribosomal protein L18a /FL=gb:NM_000980.1 gb:L05093.1" NM_000980 "ribosomal protein L18a /// small nucleolar RNA, H/ACA box 68" RPL18A /// SNORA68 6142 /// 26780 NM_000980 /// NR_000012 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200870_at NM_007178 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007178.1 /DEF=Homo sapiens unr-interacting protein (UNRIP), mRNA. /FEA=mRNA /GEN=UNRIP /PROD=unr-interacting protein /DB_XREF=gi:6005931 /UG=Hs.3727 unr-interacting protein /FL=gb:BC000162.1 gb:AB024327.1 gb:NM_007178.1 gb:AL136691.1 gb:AF161496.1" NM_007178 serine/threonine kinase receptor associated protein STRAP 11171 NM_007178 /// XM_005253294 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from mutant phenotype /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030277 // maintenance of gastrointestinal epithelium // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200871_s_at NM_002778 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002778.1 /DEF=Homo sapiens prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) (PSAP), mRNA. /FEA=mRNA /GEN=PSAP /PROD=prosaposin (variant Gaucher disease and variantmetachromatic leukodystrophy) /DB_XREF=gi:11386146 /UG=Hs.78575 prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) /FL=gb:NM_002778.1 gb:BC004275.1 gb:J03077.1 gb:D00422.1 gb:M60255.1 gb:M32221.1 gb:M60257.1 gb:M60258.1 gb:M81355.1" NM_002778 prosaposin PSAP 5660 NM_001042465 /// NM_001042466 /// NM_002778 0002576 // platelet degranulation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008289 // lipid binding // traceable author statement 200872_at NM_002966 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002966.1 /DEF=Homo sapiens S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) (S100A10), mRNA. /FEA=mRNA /GEN=S100A10 /PROD=S100 calcium-binding protein A10 /DB_XREF=gi:4506760 /UG=Hs.119301 S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) /FL=gb:M81457.1 gb:M38591.1 gb:NM_002966.1" NM_002966 S100 calcium binding protein A10 S100A10 6281 NM_002966 0001765 // membrane raft assembly // inferred from direct assay /// 0006900 // membrane budding // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction 200873_s_at NM_006585 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006585.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 8 (theta) (CCT8), mRNA. /FEA=mRNA /GEN=CCT8 /PROD=chaperonin containing TCP1, subunit 8 (theta) /DB_XREF=gi:6005726 /UG=Hs.15071 chaperonin containing TCP1, subunit 8 (theta) /FL=gb:D13627.1 gb:NM_006585.1" NM_006585 "chaperonin containing TCP1, subunit 8 (theta)" CCT8 10694 NM_001282907 /// NM_001282908 /// NM_001282909 /// NM_006585 0006200 // ATP catabolic process // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation" 200874_s_at BE796327 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE796327 /FEA=EST /DB_XREF=gi:10217525 /DB_XREF=est:601591928F1 /CLONE=IMAGE:3946015 /UG=Hs.296585 nucleolar protein (KKED repeat) /FL=gb:NM_006392.1 BE796327 "microRNA 1292 /// NOP56 ribonucleoprotein /// small nucleolar RNA, C/D box 110 /// small nucleolar RNA, C/D box 57 /// small nucleolar RNA, C/D box 86" MIR1292 /// NOP56 /// SNORD110 /// SNORD57 /// SNORD86 10528 /// 26792 /// 692201 /// 692213 /// 100302138 NM_006392 /// NR_002738 /// NR_003078 /// NR_004399 /// NR_027700 /// NR_031699 0006364 // rRNA processing // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031428 // box C/D snoRNP complex // non-traceable author statement /// 0070761 // pre-snoRNP complex // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200875_s_at NM_006392 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006392.1 /DEF=Homo sapiens nucleolar protein (KKED repeat) (NOP56), mRNA. /FEA=mRNA /GEN=NOP56 /PROD=nucleolar protein (KKED repeat) /DB_XREF=gi:5453793 /UG=Hs.296585 nucleolar protein (KKED repeat) /FL=gb:NM_006392.1" NM_006392 "microRNA 1292 /// NOP56 ribonucleoprotein /// small nucleolar RNA, C/D box 110 /// small nucleolar RNA, C/D box 57 /// small nucleolar RNA, C/D box 86" MIR1292 /// NOP56 /// SNORD110 /// SNORD57 /// SNORD86 10528 /// 26792 /// 692201 /// 692213 /// 100302138 NM_006392 /// NR_002738 /// NR_003078 /// NR_004399 /// NR_027700 /// NR_031699 0006364 // rRNA processing // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005732 // small nucleolar ribonucleoprotein complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031428 // box C/D snoRNP complex // non-traceable author statement /// 0070761 // pre-snoRNP complex // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200876_s_at NM_002793 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002793.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 1 (PSMB1), mRNA. /FEA=mRNA /GEN=PSMB1 /PROD=proteasome (prosome, macropain) subunit, betatype, 1 /DB_XREF=gi:4506192 /UG=Hs.75748 proteasome (prosome, macropain) subunit, beta type, 1 /FL=gb:BC000508.1 gb:NM_002793.1" NM_002793 "proteasome (prosome, macropain) subunit, beta type, 1" PSMB1 5689 NM_002793 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200877_at NM_006430 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006430.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 4 (delta) (CCT4), mRNA. /FEA=mRNA /GEN=CCT4 /PROD=chaperonin containing TCP1, subunit 4 (delta) /DB_XREF=gi:5453604 /UG=Hs.79150 chaperonin containing TCP1, subunit 4 (delta) /FL=gb:U38846.1 gb:AF026291.1 gb:NM_006430.1" NM_006430 "chaperonin containing TCP1, subunit 4 (delta)" CCT4 10575 NM_001256721 /// NM_006430 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200878_at AF052094 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AF052094.1 /DEF=Homo sapiens clone 23698 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360400 /UG=Hs.8136 endothelial PAS domain protein 1 /FL=gb:U51626.1 gb:U81984.1 gb:NM_001430.1 AF052094 endothelial PAS domain protein 1 EPAS1 2034 NM_001430 "0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042415 // norepinephrine metabolic process // inferred from electronic annotation /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048469 // cell maturation // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 200879_s_at NM_001430 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001430.1 /DEF=Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA. /FEA=mRNA /GEN=EPAS1 /PROD=endothelial PAS domain protein 1 /DB_XREF=gi:4503576 /UG=Hs.8136 endothelial PAS domain protein 1 /FL=gb:U51626.1 gb:U81984.1 gb:NM_001430.1" NM_001430 endothelial PAS domain protein 1 EPAS1 2034 NM_001430 "0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042415 // norepinephrine metabolic process // inferred from electronic annotation /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0048469 // cell maturation // inferred from electronic annotation /// 0048625 // myoblast fate commitment // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 200880_at AL534104 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL534104 /FEA=EST /DB_XREF=gi:12797597 /DB_XREF=est:AL534104 /CLONE=CS0DF005YF01 (3 prime) /UG=Hs.94 DnaJ (Hsp40) homolog, subfamily A, member 1 /FL=gb:D13388.1 gb:L08069.1 gb:NM_001539.1" AL534104 "DnaJ (Hsp40) homolog, subfamily A, member 1" DNAJA1 3301 NM_001539 0006457 // protein folding // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from mutant phenotype /// 0051223 // regulation of protein transport // inferred from direct assay /// 0070585 // protein localization to mitochondrion // inferred from mutant phenotype 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 200881_s_at NM_001539 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001539.1 /DEF=Homo sapiens heat shock protein, DNAJ-like 2 (HSJ2), mRNA. /FEA=mRNA /GEN=HSJ2 /PROD=heat shock protein, DNAJ-like 2 /DB_XREF=gi:4504510 /UG=Hs.94 DnaJ (Hsp40) homolog, subfamily A, member 1 /FL=gb:D13388.1 gb:L08069.1 gb:NM_001539.1" NM_001539 "DnaJ (Hsp40) homolog, subfamily A, member 1" DNAJA1 3301 NM_001539 0006457 // protein folding // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from mutant phenotype /// 0051223 // regulation of protein transport // inferred from direct assay /// 0070585 // protein localization to mitochondrion // inferred from mutant phenotype 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 200882_s_at NM_002810 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002810.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (PSMD4), mRNA. /FEA=mRNA /GEN=PSMD4 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 4 /DB_XREF=gi:5292160 /UG=Hs.148495 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 /FL=gb:BC002365.1 gb:U24704.1 gb:NM_002810.1" NM_002810 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 4" PSMD4 5710 NM_002810 /// NM_153822 /// XM_005245354 /// XM_006711464 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" "0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity" 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200883_at NM_003366 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003366.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA. /FEA=mRNA /GEN=UQCRC2 /PROD=ubiquinol-cytochrome c reductase core proteinII /DB_XREF=gi:4507842 /UG=Hs.173554 ubiquinol-cytochrome c reductase core protein II /FL=gb:BC000484.1 gb:BC003136.1 gb:J04973.1 gb:NM_003366.1" NM_003366 ubiquinol-cytochrome c reductase core protein II UQCRC2 7385 NM_003366 0006119 // oxidative phosphorylation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200884_at NM_001823 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001823.1 /DEF=Homo sapiens creatine kinase, brain (CKB), mRNA. /FEA=mRNA /GEN=CKB /PROD=creatine kinase, brain /DB_XREF=gi:4502850 /UG=Hs.173724 creatine kinase, brain /FL=gb:L47647.1 gb:BC001190.1 gb:BC004914.1 gb:M16364.1 gb:M16451.1 gb:NM_001823.1" NM_001823 "creatine kinase, brain" CKB 1152 NM_001823 0006600 // creatine metabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004111 // creatine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 200885_at NM_005167 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005167.1 /DEF=Homo sapiens ras homolog gene family, member C (ARHC), mRNA. /FEA=mRNA /GEN=ARHC /PROD=ras homolog gene family, member C /DB_XREF=gi:4885066 /UG=Hs.179735 ras homolog gene family, member C /FL=gb:L25081.1 gb:NM_005167.1" NM_005167 ras homolog family member C RHOC 389 NM_001042678 /// NM_001042679 /// NM_175744 0000910 // cytokinesis // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 200886_s_at NM_002629 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002629.1 /DEF=Homo sapiens phosphoglycerate mutase 1 (brain) (PGAM1), mRNA. /FEA=mRNA /GEN=PGAM1 /PROD=phosphoglycerate mutase 1 (brain) /DB_XREF=gi:4505752 /UG=Hs.181013 phosphoglycerate mutase 1 (brain) /FL=gb:BC000455.1 gb:NM_002629.1 gb:J04173.1" NM_002629 phosphoglycerate mutase 1 (brain) PGAM1 5223 NM_002629 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // traceable author statement /// 0006110 // regulation of glycolytic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0043456 // regulation of pentose-phosphate shunt // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045730 // respiratory burst // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004082 // bisphosphoglycerate mutase activity // inferred from electronic annotation /// 0004083 // bisphosphoglycerate 2-phosphatase activity // inferred from electronic annotation /// 0004619 // phosphoglycerate mutase activity // inferred from direct assay /// 0004619 // phosphoglycerate mutase activity // inferred from mutant phenotype /// 0004619 // phosphoglycerate mutase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction" 200887_s_at NM_007315 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007315.1 /DEF=Homo sapiens signal transducer and activator of transcription 1, 91kD (STAT1), mRNA. /FEA=mRNA /GEN=STAT1 /PROD=signal transducer and activator of transcription1, 91kD /DB_XREF=gi:6274551 /UG=Hs.21486 signal transducer and activator of transcription 1, 91kD /FL=gb:M97935.1 gb:NM_007315.1" NM_007315 "signal transducer and activator of transcription 1, 91kDa" STAT1 6772 NM_007315 /// NM_139266 /// XM_006712718 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200888_s_at NM_000978 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000978.1 /DEF=Homo sapiens ribosomal protein L23 (RPL23), mRNA. /FEA=mRNA /GEN=RPL23 /PROD=ribosomal protein L23 /DB_XREF=gi:4506604 /UG=Hs.234518 ribosomal protein L23 /FL=gb:NM_000978.1" NM_000978 "ribosomal protein L23 /// small nucleolar RNA, H/ACA box 21" RPL23 /// SNORA21 9349 /// 619505 NM_000978 /// NR_002576 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006610 // ribosomal protein import into nucleus // non-traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200889_s_at AI016620 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI016620 /FEA=EST /DB_XREF=gi:3230956 /DB_XREF=est:ov30e10.x1 /CLONE=IMAGE:1638858 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2" AI016620 "signal sequence receptor, alpha" SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200890_s_at AW006345 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW006345 /FEA=EST /DB_XREF=gi:5855123 /DB_XREF=est:wt04d05.x1 /CLONE=IMAGE:2506473 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2" AW006345 "signal sequence receptor, alpha" SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200891_s_at NM_003144 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003144.2 /DEF=Homo sapiens signal sequence receptor, alpha (translocon-associated protein alpha) (SSR1), mRNA. /FEA=mRNA /GEN=SSR1 /PROD=signal sequence receptor, alpha /DB_XREF=gi:6552340 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2" NM_003144 "signal sequence receptor, alpha" SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200892_s_at BC000451 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000451.1 /DEF=Homo sapiens, splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10, clone MGC:8454, mRNA, complete cds. /FEA=mRNA /PROD=splicing factor, arginineserine-rich(transformer 2 Drosophila homolog) 10 /DB_XREF=gi:12653362 /UG=Hs.30035 splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 /FL=gb:BC000160.1 gb:BC000451.1 gb:U61267.1 gb:U68063.1 gb:NM_004593.1" BC000451 transformer 2 beta homolog (Drosophila) TRA2B 6434 NM_001243879 /// NM_004593 /// XM_005247703 /// XM_006713724 "0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200893_at NM_004593 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004593.1 /DEF=Homo sapiens splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 (SFRS10), mRNA. /FEA=mRNA /GEN=SFRS10 /PROD=splicing factor, arginineserine-rich(transformer 2 Drosophila homolog) 10 /DB_XREF=gi:4759097 /UG=Hs.30035 splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 /FL=gb:BC000160.1 gb:BC000451.1 gb:U61267.1 gb:U68063.1 gb:NM_004593.1" NM_004593 transformer 2 beta homolog (Drosophila) TRA2B 6434 NM_001243879 /// NM_004593 /// XM_005247703 /// XM_006713724 "0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200894_s_at AA894574 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA894574 /FEA=EST /DB_XREF=gi:3030975 /DB_XREF=est:of91h10.s1 /CLONE=IMAGE:1437763 /UG=Hs.848 FK506-binding protein 4 (59kD) /FL=gb:BC001786.1 gb:M88279.1 gb:NM_002014.1 AA894574 "FK506 binding protein 4, 59kDa" FKBP4 2288 NM_002014 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006463 // steroid hormone receptor complex assembly // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0018208 // peptidyl-proline modification // /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0031111 // negative regulation of microtubule polymerization or depolymerization // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from electronic annotation /// 0046661 // male sex differentiation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from direct assay 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0005528 // FK506 binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0032767 // copper-dependent protein binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048156 // tau protein binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 200895_s_at NM_002014 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002014.1 /DEF=Homo sapiens FK506-binding protein 4 (59kD) (FKBP4), mRNA. /FEA=mRNA /GEN=FKBP4 /PROD=FK506-binding protein 4 (59kD) /DB_XREF=gi:4503728 /UG=Hs.848 FK506-binding protein 4 (59kD) /FL=gb:BC001786.1 gb:M88279.1 gb:NM_002014.1" NM_002014 "FK506 binding protein 4, 59kDa" FKBP4 2288 NM_002014 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006463 // steroid hormone receptor complex assembly // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0018208 // peptidyl-proline modification // /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from electronic annotation /// 0031111 // negative regulation of microtubule polymerization or depolymerization // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from electronic annotation /// 0046661 // male sex differentiation // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from direct assay 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0005528 // FK506 binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0032767 // copper-dependent protein binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048156 // tau protein binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 200896_x_at NM_004494 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004494.1 /DEF=Homo sapiens hepatoma-derived growth factor (high-mobility group protein 1-like) (HDGF), mRNA. /FEA=mRNA /GEN=HDGF /PROD=hepatoma-derived growth factor (high-mobilitygroup protein 1-like) /DB_XREF=gi:4758515 /UG=Hs.89525 hepatoma-derived growth factor (high-mobility group protein 1-like) /FL=gb:NM_004494.1 gb:D16431.1" NM_004494 hepatoma-derived growth factor HDGF 3068 NM_001126050 /// NM_001126051 /// NM_004494 /// XM_006711280 /// XM_006711281 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009987 // cellular process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200897_s_at NM_016081 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016081.1 /DEF=Homo sapiens palladin (KIAA0992), mRNA. /FEA=mRNA /GEN=KIAA0992 /PROD=palladin /DB_XREF=gi:7706354 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1" NM_016081 "palladin, cytoskeletal associated protein" PALLD 23022 NM_001166108 /// NM_001166109 /// NM_001166110 /// NM_016081 /// XM_005262861 /// XM_005262862 /// XM_005262863 /// XM_005262864 /// XM_005262865 /// XM_005262866 0007010 // cytoskeleton organization // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // traceable author statement 200898_s_at AK002091 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK002091.1 /DEF=Homo sapiens cDNA FLJ11229 fis, clone PLACE1008356, highly similar to Homo sapiens mRNA for KIAA0679 protein. /FEA=mRNA /DB_XREF=gi:7023763 /UG=Hs.5734 meningioma expressed antigen 5 (hyaluronidase) /FL=gb:AF036144.2 gb:NM_012215.1" AK002091 meningioma expressed antigen 5 (hyaluronidase) MGEA5 10724 NM_001142434 /// NM_012215 /// XR_246060 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006516 // glycoprotein catabolic process // traceable author statement /// 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010616 // negative regulation of cardiac muscle adaptation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0031343 // positive regulation of cell killing // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0043243 // positive regulation of protein complex disassembly // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060051 // negative regulation of protein glycosylation // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation /// 0070265 // necrotic cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation" 200899_s_at NM_012215 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012215.1 /DEF=Homo sapiens meningioma expressed antigen 5 (hyaluronidase) (MGEA5), mRNA. /FEA=mRNA /GEN=MGEA5 /PROD=meningioma expressed antigen 5 (hyaluronidase) /DB_XREF=gi:11024697 /UG=Hs.5734 meningioma expressed antigen 5 (hyaluronidase) /FL=gb:AF036144.2 gb:NM_012215.1" NM_012215 meningioma expressed antigen 5 (hyaluronidase) MGEA5 10724 NM_001142434 /// NM_012215 /// XR_246060 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006516 // glycoprotein catabolic process // traceable author statement /// 0006612 // protein targeting to membrane // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010616 // negative regulation of cardiac muscle adaptation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0031343 // positive regulation of cell killing // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0043243 // positive regulation of protein complex disassembly // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0046060 // dATP metabolic process // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060051 // negative regulation of protein glycosylation // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation /// 0070265 // necrotic cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation" 200900_s_at AI583537 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI583537 /FEA=EST /DB_XREF=gi:4569434 /DB_XREF=est:ts12d03.x1 /CLONE=IMAGE:2228357 /UG=Hs.75709 mannose-6-phosphate receptor (cation dependent) /FL=gb:NM_002355.2 gb:M16985.1 AI583537 mannose-6-phosphate receptor (cation dependent) M6PR 4074 NM_001207024 /// NM_002355 /// XM_005253376 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // traceable author statement /// 0015761 // mannose transport // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0000323 // lytic vacuole // inferred from electronic annotation /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005537 // mannose binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015578 // mannose transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200901_s_at NM_002355 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002355.2 /DEF=Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), mRNA. /FEA=mRNA /GEN=M6PR /PROD=cation-dependent mannose-6-phosphate receptorprecursor /DB_XREF=gi:10947032 /UG=Hs.75709 mannose-6-phosphate receptor (cation dependent) /FL=gb:NM_002355.2 gb:M16985.1" NM_002355 mannose-6-phosphate receptor (cation dependent) /// polyhomeotic homolog 1 (Drosophila) M6PR /// PHC1 1911 /// 4074 NM_001207024 /// NM_002355 /// NM_004426 /// XM_005253334 /// XM_005253336 /// XM_005253376 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // traceable author statement /// 0015761 // mannose transport // inferred from electronic annotation /// 0016574 // histone ubiquitination // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation 0000323 // lytic vacuole // inferred from electronic annotation /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015578 // mannose transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200902_at NM_004261 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004261.1 /DEF=Homo sapiens 15 kDa selenoprotein (SEP15), mRNA. /FEA=mRNA /GEN=SEP15 /PROD=15 kDa selenoprotein /DB_XREF=gi:4759095 /UG=Hs.90606 15 kDa selenoprotein /FL=gb:AF288991.1 gb:BC005294.1 gb:AF051894.1 gb:NM_004261.1" NM_004261 15 kDa selenoprotein 15-Sep 9403 NM_004261 /// NM_203341 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008430 // selenium binding // inferred from direct assay 200903_s_at NM_000687 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000687.1 /DEF=Homo sapiens S-adenosylhomocysteine hydrolase (AHCY), mRNA. /FEA=mRNA /GEN=AHCY /PROD=S-adenosylhomocysteine hydrolase /DB_XREF=gi:9951914 /UG=Hs.172673 S-adenosylhomocysteine hydrolase /FL=gb:M61832.1 gb:NM_000687.1" NM_000687 adenosylhomocysteinase AHCY 191 NM_000687 /// NM_001161766 /// XM_005260316 /// XM_005260317 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004013 // adenosylhomocysteinase activity // traceable author statement /// 0004455 // ketol-acid reductoisomerase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation" 200904_at X56841 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:X56841.1 /DEF=H.sapiens HLA-E gene. /FEA=mRNA /GEN=HLA-E /PROD=HLA-E /DB_XREF=gi:433491 /UG=Hs.181392 major histocompatibility complex, class I, E /FL=gb:BC002578.1 gb:NM_005516.1" X56841 "major histocompatibility complex, class I, E" HLA-E 3133 NM_005516 "0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002476 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib // inferred from direct assay /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002717 // positive regulation of natural killer cell mediated immunity // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay 200905_x_at NM_005516 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005516.1 /DEF=Homo sapiens major histocompatibility complex, class I, E (HLA-E), mRNA. /FEA=mRNA /GEN=HLA-E /PROD=major histocompatibility complex, class I, E /DB_XREF=gi:5031744 /UG=Hs.181392 major histocompatibility complex, class I, E /FL=gb:BC002578.1 gb:NM_005516.1" NM_005516 "major histocompatibility complex, class I, E" HLA-E 3133 NM_005516 "0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002476 // antigen processing and presentation of endogenous peptide antigen via MHC class Ib // inferred from direct assay /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002717 // positive regulation of natural killer cell mediated immunity // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0042270 // protection from natural killer cell mediated cytotoxicity // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0042605 // peptide antigen binding // not recorded /// 0042605 // peptide antigen binding // inferred from direct assay 200906_s_at AK025843 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK025843.1 /DEF=Homo sapiens cDNA: FLJ22190 fis, clone HRC01053. /FEA=mRNA /DB_XREF=gi:10438481 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1" AK025843 "palladin, cytoskeletal associated protein" PALLD 23022 NM_001166108 /// NM_001166109 /// NM_001166110 /// NM_016081 /// XM_005262861 /// XM_005262862 /// XM_005262863 /// XM_005262864 /// XM_005262865 /// XM_005262866 0007010 // cytoskeleton organization // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // traceable author statement 200907_s_at AU157932 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU157932 /FEA=EST /DB_XREF=gi:11019453 /DB_XREF=est:AU157932 /CLONE=PLACE1010217 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1 AU157932 "palladin, cytoskeletal associated protein" PALLD 23022 NM_001166108 /// NM_001166109 /// NM_001166110 /// NM_016081 /// XM_005262861 /// XM_005262862 /// XM_005262863 /// XM_005262864 /// XM_005262865 /// XM_005262866 0007010 // cytoskeleton organization // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // traceable author statement 200908_s_at BC005354 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BC005354.1 /DEF=Homo sapiens, ribosomal protein, large P2, clone MGC:12453, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein, large P2 /DB_XREF=gi:13529169 /UG=Hs.119500 ribosomal protein, large P2 /FL=gb:BC005354.1 gb:M17887.1 gb:NM_001004.1" BC005354 "ribosomal protein, large, P2" RPLP2 6181 NM_001004 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200909_s_at NM_001004 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001004.1 /DEF=Homo sapiens ribosomal protein, large P2 (RPLP2), mRNA. /FEA=mRNA /GEN=RPLP2 /PROD=ribosomal protein, large P2 /DB_XREF=gi:4506670 /UG=Hs.119500 ribosomal protein, large P2 /FL=gb:BC005354.1 gb:M17887.1 gb:NM_001004.1" NM_001004 "ribosomal protein, large, P2 /// small nucleolar RNA, H/ACA box 52" RPLP2 /// SNORA52 6181 /// 619565 NM_001004 /// NR_002585 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 200910_at NM_005998 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005998.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 3 (gamma) (CCT3), mRNA. /FEA=mRNA /GEN=CCT3 /PROD=chaperonin containing TCP1, subunit 3 (gamma) /DB_XREF=gi:5174726 /UG=Hs.1708 chaperonin containing TCP1, subunit 3 (gamma) /FL=gb:NM_005998.1" NM_005998 "chaperonin containing TCP1, subunit 3 (gamma) /// uncharacterized LOC101927137" CCT3 /// LOC101927137 7203 /// 101927137 NM_001008800 /// NM_001008883 /// NM_005998 /// NR_036564 /// NR_036565 /// XR_246167 /// XR_246168 /// XR_246169 /// XR_246170 /// XR_246171 /// XR_246172 /// XR_246173 /// XR_252798 /// XR_252799 /// XR_252800 /// XR_252801 /// XR_252802 /// XR_252803 /// XR_252804 /// XR_428788 /// XR_428789 /// XR_428790 /// XR_428791 /// XR_428792 /// XR_428793 /// XR_428794 /// XR_428795 /// XR_428796 /// XR_432624 /// XR_432625 /// XR_432626 /// XR_432627 /// XR_432628 /// XR_432629 /// XR_432630 /// XR_432631 /// XR_432632 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200911_s_at NM_006283 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006283.1 /DEF=Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), mRNA. /FEA=mRNA /GEN=TACC1 /PROD=transforming, acidic coiled-coil containingprotein 1 /DB_XREF=gi:5454099 /UG=Hs.173159 transforming, acidic coiled-coil containing protein 1 /FL=gb:AF049910.1 gb:NM_006283.1" NM_006283 "transforming, acidic coiled-coil containing protein 1" TACC1 6867 NM_001122824 /// NM_001146216 /// NM_006283 /// XM_005273622 /// XM_005273624 /// XM_005273625 /// XM_005273626 /// XM_005273627 /// XM_005273628 /// XM_005273629 /// XM_005273630 /// XM_005273631 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200912_s_at NM_001967 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001967.2 /DEF=Homo sapiens eukaryotic translation initiation factor 4A, isoform 2 (EIF4A2), mRNA. /FEA=mRNA /GEN=EIF4A2 /PROD=eukaryotic translation initiation factor 4A,isoform 2 /DB_XREF=gi:9945313 /UG=Hs.173912 eukaryotic translation initiation factor 4A, isoform 2 /FL=gb:D30655.1 gb:NM_001967.2" NM_001967 "eukaryotic translation initiation factor 4A2 /// microRNA 1248 /// small nucleolar RNA, H/ACA box 4 /// small nucleolar RNA, H/ACA box 63 /// small nucleolar RNA, H/ACA box 81 /// small nucleolar RNA, C/D box 2" EIF4A2 /// MIR1248 /// SNORA4 /// SNORA63 /// SNORA81 /// SNORD2 1974 /// 6043 /// 619567 /// 619568 /// 677847 /// 100302143 NM_001967 /// NR_002586 /// NR_002587 /// NR_002588 /// NR_002989 /// NR_031650 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200913_at NM_002707 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002707.1 /DEF=Homo sapiens protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (PPM1G), mRNA. /FEA=mRNA /GEN=PPM1G /PROD=protein phosphatase 1G (formerly 2C),magnesium-dependent, gamma isoform /DB_XREF=gi:4505998 /UG=Hs.17883 protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform /FL=gb:BC000057.1 gb:NM_002707.1" NM_002707 "protein phosphatase, Mg2+/Mn2+ dependent, 1G" PPM1G 5496 NM_177983 0006470 // protein dephosphorylation // traceable author statement /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200914_x_at BF589024 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF589024 /FEA=EST /DB_XREF=gi:11681348 /DB_XREF=est:naa40c08.x1 /CLONE=IMAGE:3258639 /UG=Hs.211577 kinectin 1 (kinesin receptor) /FL=gb:D13629.1 gb:L25616.1 gb:NM_004986.1 BF589024 kinectin 1 (kinesin receptor) KTN1 3895 NM_001079521 /// NM_001079522 /// NM_001271014 /// NM_004986 /// NM_182926 /// NR_073128 /// NR_073129 /// XM_006720138 /// XM_006720139 /// XM_006720140 /// XM_006720141 0007018 // microtubule-based movement // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0019894 // kinesin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200915_x_at NM_004986 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004986.1 /DEF=Homo sapiens kinectin 1 (kinesin receptor) (KTN1), mRNA. /FEA=mRNA /GEN=KTN1 /PROD=kinectin 1 (kinesin receptor) /DB_XREF=gi:4826813 /UG=Hs.211577 kinectin 1 (kinesin receptor) /FL=gb:D13629.1 gb:L25616.1 gb:NM_004986.1" NM_004986 kinectin 1 (kinesin receptor) KTN1 3895 NM_001079521 /// NM_001079522 /// NM_001271014 /// NM_004986 /// NM_182926 /// NR_073128 /// NR_073129 /// XM_006720138 /// XM_006720139 /// XM_006720140 /// XM_006720141 0007018 // microtubule-based movement // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0019894 // kinesin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200916_at NM_003564 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003564.1 /DEF=Homo sapiens transgelin 2 (TAGLN2), mRNA. /FEA=mRNA /GEN=TAGLN2 /PROD=transgelin 2 /DB_XREF=gi:4507356 /UG=Hs.75725 transgelin 2 /FL=gb:D21261.1 gb:NM_003564.1" NM_003564 transgelin 2 TAGLN2 8407 NM_001277223 /// NM_001277224 /// NM_003564 0007517 // muscle organ development // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from direct assay 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200917_s_at BG474541 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG474541 /FEA=EST /DB_XREF=gi:13406818 /DB_XREF=est:602517313F1 /CLONE=IMAGE:4649162 /UG=Hs.75730 signal recognition particle receptor (docking protein) /FL=gb:BC001162.1 gb:NM_003139.1 BG474541 signal recognition particle receptor (docking protein) SRPR 6734 NM_001177842 /// NM_003139 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005785 // signal recognition particle receptor complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005047 // signal recognition particle binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200918_s_at NM_003139 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003139.1 /DEF=Homo sapiens signal recognition particle receptor (docking protein) (SRPR), mRNA. /FEA=mRNA /GEN=SRPR /PROD=signal recognition particle receptor (dockingprotein) /DB_XREF=gi:4507222 /UG=Hs.75730 signal recognition particle receptor (docking protein) /FL=gb:BC001162.1 gb:NM_003139.1" NM_003139 signal recognition particle receptor (docking protein) SRPR 6734 NM_001177842 /// NM_003139 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005785 // signal recognition particle receptor complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005047 // signal recognition particle binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200919_at NM_004427 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004427.1 /DEF=Homo sapiens early development regulator 2 (homolog of polyhomeotic 2) (EDR2), mRNA. /FEA=mRNA /GEN=EDR2 /PROD=early development regulator 2 /DB_XREF=gi:4758241 /UG=Hs.75878 early development regulator 2 (homolog of polyhomeotic 2) /FL=gb:U89278.1 gb:NM_004427.1" NM_004427 polyhomeotic homolog 2 (Drosophila) PHC2 1912 NM_004427 /// NM_198040 /// XM_005270568 /// XM_005270570 /// XM_005270571 /// XM_005270572 /// XM_006710401 /// XM_006710402 /// XM_006710403 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200920_s_at AL535380 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL535380 /FEA=EST /DB_XREF=gi:12798873 /DB_XREF=est:AL535380 /CLONE=CS0DF009YN13 (5 prime) /UG=Hs.77054 B-cell translocation gene 1, anti-proliferative /FL=gb:NM_001731.1" AL535380 "B-cell translocation gene 1, anti-proliferative" BTG1 694 NM_001731 "0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016477 // cell migration // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0045663 // positive regulation of myoblast differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype 0003712 // transcription cofactor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // non-traceable author statement 200921_s_at NM_001731 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001731.1 /DEF=Homo sapiens B-cell translocation gene 1, anti-proliferative (BTG1), mRNA. /FEA=mRNA /GEN=BTG1 /PROD=B-cell translocation protein 1 /DB_XREF=gi:4502472 /UG=Hs.77054 B-cell translocation gene 1, anti-proliferative /FL=gb:NM_001731.1" NM_001731 "B-cell translocation gene 1, anti-proliferative" BTG1 694 NM_001731 "0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016477 // cell migration // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // inferred from direct assay /// 0045663 // positive regulation of myoblast differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype 0003712 // transcription cofactor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // non-traceable author statement 200922_at NM_006801 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006801.1 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (KDELR1), mRNA. /FEA=mRNA /GEN=KDELR1 /PROD=KDEL receptor 1 /DB_XREF=gi:5803047 /UG=Hs.78040 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 /FL=gb:NM_006801.1" NM_006801 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 KDELR1 10945 NM_006801 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005046 // KDEL sequence binding // traceable author statement /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200923_at NM_005567 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005567.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 3 binding protein (galectin 6 binding protein) (LGALS3BP), mRNA. /FEA=mRNA /GEN=LGALS3BP /PROD=galectin 6 binding protein /DB_XREF=gi:6006016 /UG=Hs.79339 lectin, galactoside-binding, soluble, 3 binding protein (galectin 6 binding protein) /FL=gb:BC002403.1 gb:BC002998.1 gb:L13210.1 gb:NM_005567.2" NM_005567 "lectin, galactoside-binding, soluble, 3 binding protein" LGALS3BP 3959 NM_005567 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200924_s_at NM_002394 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002394.1 /DEF=Homo sapiens solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (SLC3A2), mRNA. /FEA=mRNA /GEN=SLC3A2 /PROD=antigen identified by monoclonal antibodies 4F2,TRA1.10, TROP4, and T43 /DB_XREF=gi:4505140 /UG=Hs.79748 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 /FL=gb:BC001061.1 gb:J02769.1 gb:J03569.1 gb:NM_002394.1 gb:AB018010.1" NM_002394 "solute carrier family 3 (amino acid transporter heavy chain), member 2" SLC3A2 6520 NM_001012661 /// NM_001012662 /// NM_001012663 /// NM_001012664 /// NM_001013251 /// NM_002394 /// NR_037193 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006816 // calcium ion transport // non-traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015804 // neutral amino acid transport // inferred from electronic annotation /// 0015827 // tryptophan transport // inferred from sequence or structural similarity /// 0016049 // cell growth // non-traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0043330 // response to exogenous dsRNA // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060356 // leucine import // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005432 // calcium:sodium antiporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015175 // neutral amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0043169 // cation binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200925_at NM_004373 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004373.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIa polypeptide 1 (COX6A1), mRNA. /FEA=mRNA /GEN=COX6A1 /PROD=cytochrome c oxidase subunit VIa polypeptide 1 /DB_XREF=gi:10047079 /UG=Hs.180714 cytochrome c oxidase subunit VIa polypeptide 1 /FL=gb:NM_004373.1" NM_004373 cytochrome c oxidase subunit VIa polypeptide 1 COX6A1 1337 NM_004373 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005751 // mitochondrial respiratory chain complex IV // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 200926_at NM_001025 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001025.1 /DEF=Homo sapiens ribosomal protein S23 (RPS23), mRNA. /FEA=mRNA /GEN=RPS23 /PROD=ribosomal protein S23 /DB_XREF=gi:4506700 /UG=Hs.3463 ribosomal protein S23 /FL=gb:D14530.1 gb:NM_001025.1" NM_001025 ribosomal protein S23 RPS23 6228 NM_001025 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200927_s_at AA919115 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA919115 /FEA=EST /DB_XREF=gi:3059005 /DB_XREF=est:ol85g11.s1 /CLONE=IMAGE:1536452 /UG=Hs.5807 GTPase Rab14 /FL=gb:AF152463.1 gb:AF203689.1 gb:AL162081.1 gb:NM_016322.1 AA919115 "RAB14, member RAS oncogene family" RAB14 51552 NM_016322 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0006895 // Golgi to endosome transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0046907 // intracellular transport // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 200928_s_at AL162081 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:AL162081.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762K0911 (from clone DKFZp762K0911); complete cds. /FEA=mRNA /GEN=DKFZp762K0911 /PROD=hypothetical protein /DB_XREF=gi:7328165 /UG=Hs.5807 GTPase Rab14 /FL=gb:AF152463.1 gb:AF203689.1 gb:AL162081.1 gb:NM_016322.1 AL162081 "RAB14, member RAS oncogene family" RAB14 51552 NM_016322 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from sequence or structural similarity /// 0006895 // Golgi to endosome transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0046907 // intracellular transport // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042175 // nuclear outer membrane-endoplasmic reticulum membrane network // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from direct assay /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 200929_at NM_006827 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006827.1 /DEF=Homo sapiens transmembrane trafficking protein (TMP21), mRNA. /FEA=mRNA /GEN=TMP21 /PROD=transmembrane trafficking protein /DB_XREF=gi:5803200 /UG=Hs.74137 transmembrane trafficking protein /FL=gb:BC001825.1 gb:NM_006827.1" NM_006827 transmembrane emp24-like trafficking protein 10 (yeast) TMED10 10972 NM_006827 "0001101 // response to acid // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from sequence or structural similarity /// 0007030 // Golgi organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0034205 // beta-amyloid formation // inferred from mutant phenotype /// 0035459 // cargo loading into vesicle // traceable author statement /// 0035964 // COPI-coated vesicle budding // inferred from direct assay /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0048199 // vesicle targeting, to, from or within Golgi // inferred from sequence or structural similarity /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from sequence or structural similarity /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070765 // gamma-secretase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 200930_s_at AA156675 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA156675 /FEA=EST /DB_XREF=gi:1728354 /DB_XREF=est:zl18h03.s1 /CLONE=IMAGE:502325 /UG=Hs.75350 vinculin /FL=gb:NM_014000.1 AA156675 vinculin VCL 7414 NM_003373 /// NM_014000 /// XM_005270142 /// XM_005270143 0002009 // morphogenesis of an epithelium // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // traceable author statement /// 0034333 // adherens junction assembly // inferred from mutant phenotype /// 0034394 // protein localization to cell surface // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0090136 // epithelial cell-cell adhesion // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // non-traceable author statement /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0043034 // costamere // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from sequence or structural similarity /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from sequence or structural similarity 200931_s_at NM_014000 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014000.1 /DEF=Homo sapiens vinculin (VCL), transcript variant meta-VCL, mRNA. /FEA=mRNA /GEN=VCL /PROD=VCL isoform meta-VCL /DB_XREF=gi:7669549 /UG=Hs.75350 vinculin /FL=gb:NM_014000.1" NM_014000 vinculin VCL 7414 NM_003373 /// NM_014000 /// XM_005270142 /// XM_005270143 0002009 // morphogenesis of an epithelium // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // traceable author statement /// 0034333 // adherens junction assembly // inferred from mutant phenotype /// 0034394 // protein localization to cell surface // inferred from mutant phenotype /// 0043297 // apical junction assembly // inferred from mutant phenotype /// 0090136 // epithelial cell-cell adhesion // inferred from mutant phenotype 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // non-traceable author statement /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0043034 // costamere // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from sequence or structural similarity /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from sequence or structural similarity 200932_s_at NM_006400 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006400.2 /DEF=Homo sapiens dynactin 2 (p50) (DCTN2), mRNA. /FEA=mRNA /GEN=DCTN2 /PROD=dynactin 2 /DB_XREF=gi:13259506 /UG=Hs.84153 dynactin 2 (p50) /FL=gb:U50733.1 gb:BC000718.1 gb:NM_006400.2" NM_006400 dynactin 2 (p50) DCTN2 10540 NM_001261412 /// NM_001261413 /// NM_006400 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from direct assay 200933_x_at NM_001007 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001007.1 /DEF=Homo sapiens ribosomal protein S4, X-linked (RPS4X), mRNA. /FEA=mRNA /GEN=RPS4X /PROD=ribosomal protein S4, X-linked /DB_XREF=gi:4506724 /UG=Hs.108124 ribosomal protein S4, X-linked /FL=gb:BC000472.1 gb:BC002569.1 gb:M58458.1 gb:M22146.1 gb:NM_001007.1" NM_001007 "ribosomal protein S4, X-linked" RPS4X 6191 NM_001007 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from mutant phenotype" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0005844 // polysome // inferred from direct assay /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from mutant phenotype /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200934_at NM_003472 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003472.1 /DEF=Homo sapiens DEK oncogene (DNA binding) (DEK), mRNA. /FEA=mRNA /GEN=DEK /PROD=DEK oncogene (DNA binding) /DB_XREF=gi:4503248 /UG=Hs.110713 DEK oncogene (DNA binding) /FL=gb:NM_003472.1" NM_003472 DEK proto-oncogene DEK 7913 NM_001134709 /// NM_003472 /// XM_005249391 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 2000779 // regulation of double-strand break repair // inferred from mutant phenotype /// 2001032 // regulation of double-strand break repair via nonhomologous end joining // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 200935_at NM_004343 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004343.2 /DEF=Homo sapiens calreticulin (CALR), mRNA. /FEA=mRNA /GEN=CALR /PROD=calreticulin precursor /DB_XREF=gi:5921996 /UG=Hs.16488 calreticulin /FL=gb:BC002500.1 gb:M84739.1 gb:M32294.1 gb:NM_004343.2" NM_004343 calreticulin CALR 811 NM_004343 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002502 // peptide antigen assembly with MHC class I protein complex // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from genetic interaction /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0022417 // protein maturation by protein folding // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from genetic interaction /// 0045787 // positive regulation of cell cycle // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050821 // protein stabilization // traceable author statement /// 0051208 // sequestering of calcium ion // traceable author statement /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from genetic interaction /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from mutant phenotype" 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005844 // polysome // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0033018 // sarcoplasmic reticulum lumen // inferred from electronic annotation /// 0042824 // MHC class I peptide loading complex // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement /// 0071682 // endocytic vesicle lumen // traceable author statement 0001849 // complement component C1q binding // traceable author statement /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003677 // DNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0030246 // carbohydrate binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from electronic annotation /// 0044183 // protein binding involved in protein folding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // traceable author statement 200936_at NM_000973 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000973.1 /DEF=Homo sapiens ribosomal protein L8 (RPL8), mRNA. /FEA=mRNA /GEN=RPL8 /PROD=ribosomal protein L8 /DB_XREF=gi:4506662 /UG=Hs.178551 ribosomal protein L8 /FL=gb:BC000077.1 gb:NM_000973.1" NM_000973 ribosomal protein L8 RPL8 6132 NM_000973 /// NM_033301 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200937_s_at NM_000969 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000969.1 /DEF=Homo sapiens ribosomal protein L5 (RPL5), mRNA. /FEA=mRNA /GEN=RPL5 /PROD=ribosomal protein L5 /DB_XREF=gi:4506654 /UG=Hs.180946 ribosomal protein L5 /FL=gb:AF113210.1 gb:NM_000969.1 gb:U14966.1" NM_000969 "ribosomal protein L5 /// small nucleolar RNA, C/D box 21" RPL5 /// SNORD21 6083 /// 6125 NM_000969 /// NR_000006 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008097 // 5S rRNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200938_s_at AI920976 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI920976 /FEA=EST /DB_XREF=gi:5656940 /DB_XREF=est:wo16h05.x1 /CLONE=IMAGE:2455545 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1 AI920976 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 /// XM_005263464 /// XM_005263465 /// XM_005263466 /// XM_006710653 /// XM_006710654 "0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation" 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200939_s_at NM_012102 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012102.1 /DEF=Homo sapiens arginine-glutamic acid dipeptide (RE) repeats (RERE), mRNA. /FEA=mRNA /GEN=RERE /PROD=arginine-glutamic acid dipeptide (RE) repeats /DB_XREF=gi:6912253 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1" NM_012102 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 /// XM_005263464 /// XM_005263465 /// XM_005263466 /// XM_006710653 /// XM_006710654 "0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation" 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200940_s_at AB036737 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB036737.1 /DEF=Homo sapiens mRNA for RERE, complete cds. /FEA=mRNA /PROD=RERE /DB_XREF=gi:8096339 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1" AB036737 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 /// XM_005263464 /// XM_005263465 /// XM_005263466 /// XM_006710653 /// XM_006710654 "0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation" 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200941_at AK026575 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK026575.1 /DEF=Homo sapiens cDNA: FLJ22922 fis, clone KAT06722. /FEA=mRNA /DB_XREF=gi:10439459 /UG=Hs.250899 heat shock factor binding protein 1 /FL=gb:AF068754.1 gb:NM_001537.1" AK026575 heat shock factor binding protein 1 HSBP1 3281 NM_001537 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement 200942_s_at NM_001537 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001537.1 /DEF=Homo sapiens heat shock factor binding protein 1 (HSBP1), mRNA. /FEA=mRNA /GEN=HSBP1 /PROD=heat shock factor binding protein 1 /DB_XREF=gi:4557646 /UG=Hs.250899 heat shock factor binding protein 1 /FL=gb:AF068754.1 gb:NM_001537.1" NM_001537 heat shock factor binding protein 1 HSBP1 3281 NM_001537 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement 200943_at NM_004965 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004965.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 14 (HMG14), mRNA. /FEA=mRNA /GEN=HMG14 /PROD=high-mobility group (nonhistone chromosomal)protein 14 /DB_XREF=gi:4826757 /UG=Hs.251064 high-mobility group (nonhistone chromosomal) protein 14 /FL=gb:BC000075.1 gb:J02621.1 gb:NM_004965.1" NM_004965 high mobility group nucleosome binding domain 1 HMGN1 3150 NM_004965 "0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0040034 // regulation of development, heterochronic // inferred from electronic annotation /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 200944_s_at NM_004965 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004965.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 14 (HMG14), mRNA. /FEA=mRNA /GEN=HMG14 /PROD=high-mobility group (nonhistone chromosomal)protein 14 /DB_XREF=gi:4826757 /UG=Hs.251064 high-mobility group (nonhistone chromosomal) protein 14 /FL=gb:BC000075.1 gb:J02621.1 gb:NM_004965.1" NM_004965 high mobility group nucleosome binding domain 1 /// uncharacterized LOC101927733 HMGN1 /// LOC101927733 3150 /// 101927733 NM_004965 /// XR_242845 /// XR_247614 /// XR_252852 "0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0040034 // regulation of development, heterochronic // inferred from electronic annotation /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 200945_s_at NM_014933 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014933.1 /DEF=Homo sapiens yeast Sec31p homolog (KIAA0905), mRNA. /FEA=mRNA /GEN=KIAA0905 /PROD=yeast Sec31p homolog /DB_XREF=gi:7662369 /UG=Hs.70266 yeast Sec31p homolog /FL=gb:AB018359.1 gb:NM_014933.1 gb:AF139184.1" NM_014933 SEC31 homolog A (S. cerevisiae) SEC31A 22872 NM_001077206 /// NM_001077207 /// NM_001077208 /// NM_001191049 /// NM_014933 /// NM_016211 /// XM_005262847 /// XM_005262849 /// XM_005262850 /// XM_005262851 /// XM_005262852 /// XM_005262854 /// XM_006714141 /// XM_006714142 /// XM_006714143 /// XM_006714144 /// XM_006714145 /// XM_006714146 /// XM_006714147 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030120 // vesicle coat // inferred from direct assay /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0030134 // ER to Golgi transport vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 200946_x_at AI339331 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI339331 /FEA=EST /DB_XREF=gi:4076258 /DB_XREF=est:qt01g12.x1 /CLONE=IMAGE:1946374 /UG=Hs.77508 glutamate dehydrogenase 1 /FL=gb:J03248.1 gb:M37154.1 gb:M20867.1 gb:NM_005271.1 AI339331 glutamate dehydrogenase 1 GLUD1 2746 NM_005271 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072350 // tricarboxylic acid metabolic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004352 // glutamate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // not recorded /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016639 // oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0043531 // ADP binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay /// 0070728 // leucine binding // inferred from direct assay" 200947_s_at NM_005271 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005271.1 /DEF=Homo sapiens glutamate dehydrogenase 1 (GLUD1), mRNA. /FEA=mRNA /GEN=GLUD1 /PROD=glutamate dehydrogenase 1 /DB_XREF=gi:4885280 /UG=Hs.77508 glutamate dehydrogenase 1 /FL=gb:J03248.1 gb:M37154.1 gb:M20867.1 gb:NM_005271.1" NM_005271 glutamate dehydrogenase 1 GLUD1 2746 NM_005271 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032024 // positive regulation of insulin secretion // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072350 // tricarboxylic acid metabolic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004352 // glutamate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // not recorded /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016639 // oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0043531 // ADP binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay /// 0070728 // leucine binding // inferred from direct assay" 200948_at NM_005439 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005439.1 /DEF=Homo sapiens myeloid leukemia factor 2 (MLF2), mRNA. /FEA=mRNA /GEN=MLF2 /PROD=myeloid leukemia factor 2 /DB_XREF=gi:4885486 /UG=Hs.79026 myeloid leukemia factor 2 /FL=gb:BC000898.1 gb:BC002340.1 gb:U57342.1 gb:AF070539.1 gb:NM_005439.1" NM_005439 myeloid leukemia factor 2 MLF2 8079 NM_005439 /// NR_026581 0006952 // defense response // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 200949_x_at NM_001023 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001023.1 /DEF=Homo sapiens ribosomal protein S20 (RPS20), mRNA. /FEA=mRNA /GEN=RPS20 /PROD=ribosomal protein S20 /DB_XREF=gi:4506696 /UG=Hs.8102 ribosomal protein S20 /FL=gb:L06498.1 gb:NM_001023.1" NM_001023 "ribosomal protein S20 /// small nucleolar RNA, C/D box 54" RPS20 /// SNORD54 6224 /// 26795 NM_001023 /// NM_001146227 /// NR_002437 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200950_at NM_006409 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006409.1 /DEF=Homo sapiens actin related protein 23 complex, subunit 1A (41 kD) (ARPC1A), mRNA. /FEA=mRNA /GEN=ARPC1A /PROD=actin related protein 23 complex, subunit 1A(41 kD) /DB_XREF=gi:5454077 /UG=Hs.90370 actin related protein 23 complex, subunit 1A (41 kD) /FL=gb:NM_006409.1" NM_006409 "actin related protein 2/3 complex, subunit 1A, 41kDa" ARPC1A 10552 NM_001190996 /// NM_006409 0030036 // actin cytoskeleton organization // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200951_s_at AW026491 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW026491 /FEA=EST /DB_XREF=gi:5880021 /DB_XREF=est:wv14b06.x1 /CLONE=IMAGE:2529491 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 AW026491 cyclin D2 CCND2 894 NM_001759 /// XM_005253813 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 200952_s_at AI635187 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI635187 /FEA=EST /DB_XREF=gi:4686517 /DB_XREF=est:tz22b10.x1 /CLONE=IMAGE:2289307 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 AI635187 cyclin D2 CCND2 894 NM_001759 /// XM_005253813 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 200953_s_at NM_001759 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001759.1 /DEF=Homo sapiens cyclin D2 (CCND2), mRNA. /FEA=mRNA /GEN=CCND2 /PROD=cyclin D2 /DB_XREF=gi:4502616 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1" NM_001759 cyclin D2 CCND2 894 NM_001759 /// XM_005253813 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 200954_at NM_001694 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001694.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD (ATP6L), mRNA. /FEA=mRNA /GEN=ATP6L /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 16kD /DB_XREF=gi:4502312 /UG=Hs.76159 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD /FL=gb:BC004537.1 gb:M62762.1 gb:NM_001694.1" NM_001694 "ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c" ATP6V0C 527 NM_001198569 /// NM_001694 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005765 // lysosomal membrane // inferred from direct assay /// 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // traceable author statement /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 200955_at NM_006839 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006839.1 /DEF=Homo sapiens inner membrane protein, mitochondrial (mitofilin) (IMMT), mRNA. /FEA=mRNA /GEN=IMMT /PROD=inner membrane protein, mitochondrial(mitofilin) /DB_XREF=gi:5803114 /UG=Hs.78504 inner membrane protein, mitochondrial (mitofilin) /FL=gb:L42572.1 gb:BC002412.1 gb:D21094.1 gb:NM_006839.1" NM_006839 "inner membrane protein, mitochondrial" IMMT 10989 NM_001100169 /// NM_001100170 /// NM_006839 /// XM_005264110 /// XM_005264113 /// XM_005264114 0009409 // response to cold // inferred from electronic annotation /// 0051560 // mitochondrial calcium ion homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200956_s_at BE795648 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE795648 /FEA=EST /DB_XREF=gi:10216846 /DB_XREF=est:601590631F1 /CLONE=IMAGE:3945006 /UG=Hs.79162 structure specific recognition protein 1 /FL=gb:BC005116.1 gb:M86737.1 gb:NM_003146.1 BE795648 structure specific recognition protein 1 SSRP1 6749 NM_003146 /// XM_005274194 "0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200957_s_at NM_003146 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003146.1 /DEF=Homo sapiens structure specific recognition protein 1 (SSRP1), mRNA. /FEA=mRNA /GEN=SSRP1 /PROD=structure specific recognition protein 1 /DB_XREF=gi:4507240 /UG=Hs.79162 structure specific recognition protein 1 /FL=gb:BC005116.1 gb:M86737.1 gb:NM_003146.1" NM_003146 structure specific recognition protein 1 SSRP1 6749 NM_003146 /// XM_005274194 "0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 200958_s_at NM_005625 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005625.1 /DEF=Homo sapiens syndecan binding protein (syntenin) (SDCBP), mRNA. /FEA=mRNA /GEN=SDCBP /PROD=syndecan binding protein (syntenin) /DB_XREF=gi:5032082 /UG=Hs.8180 syndecan binding protein (syntenin) /FL=gb:AF000652.1 gb:NM_005625.1" NM_005625 syndecan binding protein (syntenin) SDCBP 6386 NM_001007067 /// NM_001007068 /// NM_001007069 /// NM_001007070 /// NM_005625 /// XM_005251280 "0006612 // protein targeting to membrane // non-traceable author statement /// 0006930 // substrate-dependent cell migration, cell extension // non-traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred by curator" 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005895 // interleukin-5 receptor complex // inferred from sequence or structural similarity /// 0005912 // adherens junction // non-traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005137 // interleukin-5 receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0019838 // growth factor binding // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0045545 // syndecan binding // inferred from physical interaction /// 0045545 // syndecan binding // non-traceable author statement /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 200959_at NM_004960 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004960.1 /DEF=Homo sapiens fusion, derived from t(12;16) malignant liposarcoma (FUS), mRNA. /FEA=mRNA /GEN=FUS /PROD=fusion, derived from t(12;16) malignantliposarcoma /DB_XREF=gi:4826733 /UG=Hs.99969 fusion, derived from t(12;16) malignant liposarcoma /FL=gb:BC000402.1 gb:BC002459.1 gb:NM_004960.1" NM_004960 FUS RNA binding protein FUS 2521 NM_001010850 /// NM_001170634 /// NM_001170937 /// NM_004960 /// NR_028388 /// XM_005255233 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200960_x_at NM_007096 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007096.1 /DEF=Homo sapiens clathrin, light polypeptide (Lca) (CLTA), transcript variant brain-specific, mRNA. /FEA=mRNA /GEN=CLTA /PROD=clathrin, light polypeptide A (Lca) isoform b /DB_XREF=gi:6005992 /UG=Hs.104143 clathrin, light polypeptide (Lca) /FL=gb:M20471.1 gb:NM_007096.1" NM_007096 "clathrin, light chain A" CLTA 1211 NM_001076677 /// NM_001184760 /// NM_001184761 /// NM_001184762 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032050 // clathrin heavy chain binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 200961_at NM_012248 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012248.1 /DEF=Homo sapiens selenophosphate synthetase 2 (SPS2), mRNA. /FEA=mRNA /GEN=SPS2 /PROD=selenophosphate synthetase 2 /DB_XREF=gi:7657612 /UG=Hs.118725 selenophosphate synthetase 2 /FL=gb:BC002381.1 gb:U43286.1 gb:NM_012248.1" NM_012248 selenophosphate synthetase 2 SEPHS2 22928 NM_012248 0008152 // metabolic process // inferred from electronic annotation /// 0016260 // selenocysteine biosynthetic process // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004756 // selenide, water dikinase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation" 200962_at AI348010 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI348010 /FEA=EST /DB_XREF=gi:4085216 /DB_XREF=est:qp61b10.x1 /CLONE=IMAGE:1927483 /UG=Hs.184014 ribosomal protein L31 /FL=gb:NM_000993.1 AI348010 ribosomal protein L31 RPL31 6160 NM_000993 /// NM_001098577 /// NM_001099693 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200963_x_at NM_000993 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000993.1 /DEF=Homo sapiens ribosomal protein L31 (RPL31), mRNA. /FEA=mRNA /GEN=RPL31 /PROD=ribosomal protein L31 /DB_XREF=gi:4506632 /UG=Hs.184014 ribosomal protein L31 /FL=gb:NM_000993.1" NM_000993 ribosomal protein L31 RPL31 6160 NM_000993 /// NM_001098577 /// NM_001099693 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 200964_at NM_003334 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003334.1 /DEF=Homo sapiens ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) (UBE1), mRNA. /FEA=mRNA /GEN=UBE1 /PROD=ubiquitin-activating enzyme E1 (A1S9T and BN75temperature sensitivity complementing) /DB_XREF=gi:4507762 /UG=Hs.2055 ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) /FL=gb:M58028.1 gb:NM_003334.1" NM_003334 ubiquitin-like modifier activating enzyme 1 UBA1 7317 NM_003334 /// NM_153280 /// XM_005272648 /// XM_005272649 /// XM_005272650 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // not recorded /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019941 // modification-dependent protein catabolic process // not recorded 0000792 // heterochromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0010008 // endosome membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030867 // rough endoplasmic reticulum membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200965_s_at NM_006720 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006720.1 /DEF=Homo sapiens actin binding LIM protein 1 (ABLIM), transcript variant ABLIM-s, mRNA. /FEA=mRNA /GEN=ABLIM /PROD=actin-binding LIM protein 1, isoform s /DB_XREF=gi:5921987 /UG=Hs.158203 actin binding LIM protein 1 /FL=gb:D31883.1 gb:NM_006720.1" NM_006720 actin binding LIM protein 1 ABLIM1 3983 NM_001003407 /// NM_001003408 /// NM_002313 /// NM_006720 /// XM_005269818 /// XM_005269819 /// XM_005269820 /// XM_005269821 /// XM_005269822 /// XM_005269823 /// XM_005269824 /// XM_005269825 /// XM_005269826 /// XM_005269827 /// XM_005269828 /// XM_005269830 /// XM_006717837 /// XM_006717838 /// XM_006717839 /// XM_006717840 /// XM_006717841 /// XM_006717842 /// XM_006717843 /// XM_006717844 /// XM_006717845 /// XM_006717846 /// XM_006717847 /// XM_006717848 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200966_x_at NM_000034 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000034.1 /DEF=Homo sapiens aldolase A, fructose-bisphosphate (ALDOA), mRNA. /FEA=mRNA /GEN=ALDOA /PROD=aldolase A /DB_XREF=gi:4557304 /UG=Hs.273415 aldolase A, fructose-bisphosphate /FL=gb:BC004333.1 gb:M11560.1 gb:NM_000034.1" NM_000034 "aldolase A, fructose-bisphosphate" ALDOA 226 NM_000034 /// NM_001127617 /// NM_001243175 /// NM_001243177 /// NM_184041 /// NM_184043 /// XM_006721109 "0002576 // platelet degranulation // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from mutant phenotype /// 0006096 // glycolytic process // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0006941 // striated muscle contraction // inferred from mutant phenotype /// 0007015 // actin filament organization // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046716 // muscle cell cellular homeostasis // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from sequence or structural similarity" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031430 // M band // inferred from electronic annotation /// 0031674 // I band // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015631 // tubulin binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070061 // fructose binding // inferred from direct assay 200967_at NM_000942 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000942.1 /DEF=Homo sapiens peptidylprolyl isomerase B (cyclophilin B) (PPIB), mRNA. /FEA=mRNA /GEN=PPIB /PROD=peptidylprolyl isomerase B (cyclophilin B) /DB_XREF=gi:4758949 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) /FL=gb:BC001125.1 gb:M60857.1 gb:M63573.1 gb:NM_000942.1" NM_000942 peptidylprolyl isomerase B (cyclophilin B) PPIB 5479 NM_000942 0000413 // protein peptidyl-prolyl isomerization // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060348 // bone development // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from mutant phenotype /// 1901873 // regulation of post-translational protein modification // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032991 // macromolecular complex // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from sequence or structural similarity /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from sequence or structural similarity /// 0016853 // isomerase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200968_s_at NM_000942 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000942.1 /DEF=Homo sapiens peptidylprolyl isomerase B (cyclophilin B) (PPIB), mRNA. /FEA=mRNA /GEN=PPIB /PROD=peptidylprolyl isomerase B (cyclophilin B) /DB_XREF=gi:4758949 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) /FL=gb:BC001125.1 gb:M60857.1 gb:M63573.1 gb:NM_000942.1" NM_000942 peptidylprolyl isomerase B (cyclophilin B) PPIB 5479 NM_000942 0000413 // protein peptidyl-prolyl isomerization // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060348 // bone development // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from mutant phenotype /// 1901873 // regulation of post-translational protein modification // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032991 // macromolecular complex // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from sequence or structural similarity /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from sequence or structural similarity /// 0016853 // isomerase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from sequence or structural similarity /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 200969_at BG107676 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG107676 /FEA=EST /DB_XREF=gi:12601522 /DB_XREF=est:602277844F1 /CLONE=IMAGE:4365370 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 BG107676 uncharacterized LOC101928061 /// stress-associated endoplasmic reticulum protein 1 LOC101928061 /// SERP1 27230 /// 101928061 NM_014445 /// XR_241595 /// XR_249518 /// XR_251476 0001501 // skeletal system development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200970_s_at AL136807 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:AL136807.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L1621 (from clone DKFZp434L1621); complete cds. /FEA=mRNA /GEN=DKFZp434L1621 /PROD=hypothetical protein /DB_XREF=gi:12053124 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 AL136807 stress-associated endoplasmic reticulum protein 1 SERP1 27230 NM_014445 0001501 // skeletal system development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200971_s_at NM_014445 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014445.1 /DEF=Homo sapiens stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 (SERP1), mRNA. /FEA=mRNA /GEN=SERP1 /PROD=stress-associated endoplasmic reticulum protein1; ribosome associated membrane protein 4 /DB_XREF=gi:7657551 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1" NM_014445 uncharacterized LOC101928061 /// stress-associated endoplasmic reticulum protein 1 LOC101928061 /// SERP1 27230 /// 101928061 NM_014445 /// XR_241595 /// XR_249518 /// XR_251476 0001501 // skeletal system development // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048644 // muscle organ morphogenesis // inferred from electronic annotation /// 0060124 // positive regulation of growth hormone secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005840 // ribosome // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 200972_at BC000704 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000704.1 /DEF=Homo sapiens, tetraspan 3, clone MGC:965, mRNA, complete cds. /FEA=mRNA /PROD=tetraspan 3 /DB_XREF=gi:12653830 /UG=Hs.100090 tetraspan 3 /FL=gb:BC000704.1 gb:BC004280.1 gb:AF054840.1 gb:NM_005724.1 gb:AF133423.1" BC000704 tetraspanin 3 TSPAN3 10099 NM_001168412 /// NM_005724 /// NM_198902 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200973_s_at NM_005724 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005724.1 /DEF=Homo sapiens tetraspan 3 (TSPAN-3), mRNA. /FEA=mRNA /GEN=TSPAN-3 /PROD=tetraspan 3 /DB_XREF=gi:5032200 /UG=Hs.100090 tetraspan 3 /FL=gb:BC000704.1 gb:BC004280.1 gb:AF054840.1 gb:NM_005724.1 gb:AF133423.1" NM_005724 tetraspanin 3 TSPAN3 10099 NM_001168412 /// NM_005724 /// NM_198902 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 200974_at NM_001613 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001613.1 /DEF=Homo sapiens actin, alpha 2, smooth muscle, aorta (ACTA2), mRNA. /FEA=mRNA /GEN=ACTA2 /PROD=alpha 2 actin /DB_XREF=gi:4501882 /UG=Hs.195851 actin, alpha 2, smooth muscle, aorta /FL=gb:J05192.1 gb:NM_001613.1" NM_001613 "actin, alpha 2, smooth muscle, aorta" ACTA2 59 NM_001141945 /// NM_001613 0006936 // muscle contraction // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0014829 // vascular smooth muscle contraction // inferred from electronic annotation /// 0030240 // skeletal muscle thin filament assembly // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0055008 // cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0072144 // glomerular mesangial cell development // inferred from expression pattern 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity 200975_at NM_000310 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000310.1 /DEF=Homo sapiens palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) (PPT1), mRNA. /FEA=mRNA /GEN=PPT1 /PROD=palmitoyl-protein thioesterase 1(ceroid-lipofuscinosis, neuronal 1, infantile) /DB_XREF=gi:4506030 /UG=Hs.3873 palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) /FL=gb:U44772.1 gb:NM_000310.1" NM_000310 palmitoyl-protein thioesterase 1 PPT1 5538 NM_000310 /// NM_001142604 /// XM_005271007 /// XM_005271008 0002084 // protein depalmitoylation // inferred from direct assay /// 0002084 // protein depalmitoylation // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0006907 // pinocytosis // inferred from mutant phenotype /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007420 // brain development // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0015031 // protein transport // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from direct assay /// 0030149 // sphingolipid catabolic process // traceable author statement /// 0030163 // protein catabolic process // non-traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0031579 // membrane raft organization // inferred from mutant phenotype /// 0032429 // regulation of phospholipase A2 activity // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from mutant phenotype /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0044265 // cellular macromolecule catabolic process // inferred from electronic annotation /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0048549 // positive regulation of pinocytosis // inferred from mutant phenotype /// 0048666 // neuron development // traceable author statement /// 0050803 // regulation of synapse structure and activity // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051181 // cofactor transport // inferred from mutant phenotype /// 0051186 // cofactor metabolic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008474 // palmitoyl-(protein) hydrolase activity // inferred from direct assay /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from mutant phenotype /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from sequence or structural similarity /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 200976_s_at NM_006024 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006024.2 /DEF=Homo sapiens Tax1 (human T-cell leukemia virus type I) binding protein 1 (TAX1BP1), mRNA. /FEA=mRNA /GEN=TAX1BP1 /PROD=Tax1 (human T-cell leukemia virus type I)binding protein 1 /DB_XREF=gi:5803188 /UG=Hs.5437 Tax1 (human T-cell leukemia virus type I) binding protein 1 /FL=gb:U33821.2 gb:NM_006024.2 gb:AF090891.1 gb:AF268075.1" NM_006024 Tax1 (human T-cell leukemia virus type I) binding protein 1 TAX1BP1 8887 NM_001079864 /// NM_001206901 /// NM_001206902 /// NM_006024 /// XM_005249900 0006915 // apoptotic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from sequence or structural similarity 200977_s_at AF090891 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF090891.1 /DEF=Homo sapiens clone HQ0105 PRO0105 mRNA, complete cds. /FEA=mRNA /PROD=PRO0105 /DB_XREF=gi:6690159 /UG=Hs.5437 Tax1 (human T-cell leukemia virus type I) binding protein 1 /FL=gb:U33821.2 gb:NM_006024.2 gb:AF090891.1 gb:AF268075.1" AF090891 Tax1 (human T-cell leukemia virus type I) binding protein 1 TAX1BP1 8887 NM_001079864 /// NM_001206901 /// NM_001206902 /// NM_006024 /// XM_005249900 0006915 // apoptotic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from sequence or structural similarity 200978_at NM_005917 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005917.1 /DEF=Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), mRNA. /FEA=mRNA /GEN=MDH1 /PROD=malate dehydrogenase 1, NAD (soluble) /DB_XREF=gi:5174538 /UG=Hs.75375 malate dehydrogenase 1, NAD (soluble) /FL=gb:D55654.1 gb:U20352.1 gb:NM_005917.1" NM_005917 "malate dehydrogenase 1, NAD (soluble)" MDH1 4190 NM_001199111 /// NM_001199112 /// NM_005917 /// XM_005264320 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006108 // malate metabolic process // inferred from electronic annotation /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016615 // malate dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030060 // L-malate dehydrogenase activity // traceable author statement /// 0047860 // diiodophenylpyruvate reductase activity // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 200979_at BF739979 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF739979 /FEA=EST /DB_XREF=gi:12066655 /DB_XREF=est:7o41g06.x1 /CLONE=IMAGE:3576778 /UG=Hs.1023 pyruvate dehydrogenase (lipoamide) alpha 1 /FL=gb:L48690.1 gb:BC002406.1 gb:J03575.1 gb:M24848.1 gb:L13318.1 gb:NM_000284.1 BF739979 pyruvate dehydrogenase (lipoamide) alpha 1 PDHA1 5160 NM_000284 /// NM_001173454 /// NM_001173455 /// NM_001173456 /// XM_006724495 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006086 // acetyl-CoA biosynthetic process from pyruvate // inferred from direct assay /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045254 // pyruvate dehydrogenase complex // inferred from direct assay "0004738 // pyruvate dehydrogenase activity // inferred from direct assay /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation" 200980_s_at NM_000284 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000284.1 /DEF=Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), mRNA. /FEA=mRNA /GEN=PDHA1 /PROD=pyruvate dehydrogenase (lipoamide) alpha 1 /DB_XREF=gi:4505684 /UG=Hs.1023 pyruvate dehydrogenase (lipoamide) alpha 1 /FL=gb:L48690.1 gb:BC002406.1 gb:J03575.1 gb:M24848.1 gb:L13318.1 gb:NM_000284.1" NM_000284 pyruvate dehydrogenase (lipoamide) alpha 1 PDHA1 5160 NM_000284 /// NM_001173454 /// NM_001173455 /// NM_001173456 /// XM_006724495 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006086 // acetyl-CoA biosynthetic process from pyruvate // inferred from direct assay /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045254 // pyruvate dehydrogenase complex // inferred from direct assay "0004738 // pyruvate dehydrogenase activity // inferred from direct assay /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation" 200981_x_at NM_016592 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016592.1 /DEF=Homo sapiens neuroendocrine secretory protein 55 (NESP55), mRNA. /FEA=mRNA /GEN=NESP55 /PROD=neuroendocrine secretory protein 55 /DB_XREF=gi:7706588 /UG=Hs.113368 neuroendocrine secretory protein 55 /FL=gb:AF105253.1 gb:NM_016592.1" NM_016592 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 /// XM_005260401 /// XM_005260402 /// XM_006723781 /// XM_006723782 0001501 // skeletal system development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from sequence or structural similarity /// 0007565 // female pregnancy // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007606 // sensory perception of chemical stimulus // not recorded /// 0007608 // sensory perception of smell // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009306 // protein secretion // non-traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040032 // post-embryonic body morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0046907 // intracellular transport // non-traceable author statement /// 0048589 // developmental growth // inferred from direct assay /// 0048589 // developmental growth // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050890 // cognition // inferred from direct assay /// 0050890 // cognition // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060348 // bone development // inferred from direct assay /// 0060348 // bone development // inferred from mutant phenotype /// 0060789 // hair follicle placode formation // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from direct assay /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071107 // response to parathyroid hormone // inferred from mutant phenotype /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071380 // cellular response to prostaglandin E stimulus // inferred from sequence or structural similarity /// 0071514 // genetic imprinting // inferred from electronic annotation /// 0071870 // cellular response to catecholamine stimulus // inferred from sequence or structural similarity /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0004016 // adenylate cyclase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // inferred from direct assay /// 0005159 // insulin-like growth factor receptor binding // /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031698 // beta-2 adrenergic receptor binding // /// 0031748 // D1 dopamine receptor binding // /// 0031852 // mu-type opioid receptor binding // not recorded /// 0035255 // ionotropic glutamate receptor binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051430 // corticotropin-releasing hormone receptor 1 binding // 200982_s_at NM_001155 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001155.2 /DEF=Homo sapiens annexin A6 (ANXA6), transcript variant 1, mRNA. /FEA=mRNA /GEN=ANXA6 /PROD=annexin VI isoform 1 /DB_XREF=gi:4809274 /UG=Hs.118796 annexin A6 /FL=gb:J03578.1 gb:D00510.1 gb:NM_001155.2" NM_001155 annexin A6 ANXA6 309 NM_001155 /// NM_001193544 /// NM_004033 /// XM_005268432 0006816 // calcium ion transport // inferred from electronic annotation /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from mutant phenotype /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0008289 // lipid binding // inferred from mutant phenotype /// 0015276 // ligand-gated ion channel activity // inferred from mutant phenotype /// 0015485 // cholesterol binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 200983_x_at BF983379 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF983379 /FEA=EST /DB_XREF=gi:12386191 /DB_XREF=est:602305270F1 /CLONE=IMAGE:4396576 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1" BF983379 "CD59 molecule, complement regulatory protein" CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0001775 // cell activation // not recorded /// 0001971 // negative regulation of activation of membrane attack complex // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // not recorded /// 0005515 // protein binding // inferred from physical interaction 200984_s_at X16447 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:X16447.1 /DEF=Human mRNA for CD59, an LY-6-like protein regulating complement membrane attack. /FEA=mRNA /PROD=precursor polypeptide (AA -25 to 103) /DB_XREF=gi:29805 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1" X16447 "CD59 molecule, complement regulatory protein" CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0001775 // cell activation // not recorded /// 0001971 // negative regulation of activation of membrane attack complex // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // not recorded /// 0005515 // protein binding // inferred from physical interaction 200985_s_at NM_000611 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000611.1 /DEF=Homo sapiens CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) (CD59), mRNA. /FEA=mRNA /GEN=CD59 /PROD=CD59 antigen p18-20 (antigen identified bymonoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /DB_XREF=gi:10835164 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1" NM_000611 "CD59 molecule, complement regulatory protein" CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0001775 // cell activation // not recorded /// 0001971 // negative regulation of activation of membrane attack complex // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement 0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0031362 // anchored component of external side of plasma membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043218 // compact myelin // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001848 // complement binding // not recorded /// 0005515 // protein binding // inferred from physical interaction 200986_at NM_000062 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000062.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), mRNA. /FEA=mRNA /GEN=SERPING1 /PROD=complement component 1 inhibitor precursor /DB_XREF=gi:4557378 /UG=Hs.151242 serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 /FL=gb:M13690.1 gb:M13656.1 gb:NM_000062.1" NM_000062 "serpin peptidase inhibitor, clade G (C1 inhibitor), member 1" SERPING1 710 NM_000062 /// NM_001032295 "0001869 // negative regulation of complement activation, lectin pathway // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from electronic annotation /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045916 // negative regulation of complement activation // inferred from electronic annotation" 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 200987_x_at AA758755 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA758755 /FEA=EST /DB_XREF=gi:2806618 /DB_XREF=est:ah80c08.s1 /CLONE=1321934 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:NM_005789.1 gb:U11292.1" AA758755 "proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" PSME3 10197 NM_001267045 /// NM_005789 /// NM_176863 /// NR_049772 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0097371 // MDM2/MDM4 family protein binding // inferred from direct assay 200988_s_at NM_005789 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005789.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (PSME3), mRNA. /FEA=mRNA /GEN=PSME3 /PROD=proteasome (prosome, macropain) activatorsubunit 3 (PA28 gamma; Ki) /DB_XREF=gi:5031996 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:NM_005789.1 gb:U11292.1" NM_005789 "proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)" PSME3 10197 NM_001267045 /// NM_005789 /// NM_176863 /// NR_049772 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0097371 // MDM2/MDM4 family protein binding // inferred from direct assay 200989_at NM_001530 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001530.1 /DEF=Homo sapiens hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A), mRNA. /FEA=mRNA /GEN=HIF1A /PROD=hypoxia-inducible factor 1, alpha subunit (basichelix-loop-helix transcription factor) /DB_XREF=gi:4504384 /UG=Hs.197540 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) /FL=gb:U29165.1 gb:AF304431.1 gb:NM_001530.1 gb:AF207601.1 gb:AF207602.1 gb:U22431.1" NM_001530 "hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)" HIF1A 3091 NM_001243084 /// NM_001530 /// NM_181054 "0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001922 // B-1 B cell homeostasis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred by curator /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003208 // cardiac ventricle morphogenesis // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006110 // regulation of glycolytic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from direct assay /// 0010573 // vascular endothelial growth factor production // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // inferred from mutant phenotype /// 0021502 // neural fold elevation formation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0032007 // negative regulation of TOR signaling // inferred from electronic annotation /// 0032364 // oxygen homeostasis // inferred from direct assay /// 0032722 // positive regulation of chemokine production // traceable author statement /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0032963 // collagen metabolic process // inferred from sequence or structural similarity /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred by curator /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred by curator /// 0045766 // positive regulation of angiogenesis // inferred by curator /// 0045821 // positive regulation of glycolytic process // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045926 // negative regulation of growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0046886 // positive regulation of hormone biosynthetic process // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0051541 // elastin metabolic process // inferred from sequence or structural similarity /// 0060574 // intestinal epithelial cell maturation // inferred from electronic annotation /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from electronic annotation /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0061419 // positive regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from mutant phenotype /// 0070101 // positive regulation of chemokine-mediated signaling pathway // inferred by curator /// 0070243 // regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070244 // negative regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071456 // cellular response to hypoxia // traceable author statement /// 0071542 // dopaminergic neuron differentiation // inferred from electronic annotation /// 2001054 // negative regulation of mesenchymal cell apoptotic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031514 // motile cilium // inferred from electronic annotation 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0000989 // transcription factor binding transcription factor activity // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 200990_at NM_005762 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005762.1 /DEF=Homo sapiens KRAB-associated protein 1 (TIF1B), mRNA. /FEA=mRNA /GEN=TIF1B /PROD=KRAB-associated protein 1 /DB_XREF=gi:5032178 /UG=Hs.228059 KRAB-associated protein 1 /FL=gb:BC004978.1 gb:U78773.1 gb:U95040.1 gb:NM_005762.1" NM_005762 tripartite motif containing 28 TRIM28 10155 NM_005762 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0060028 // convergent extension involved in axis elongation // inferred from electronic annotation /// 0060669 // embryonic placenta morphogenesis // inferred from electronic annotation /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay" 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0035851 // Krueppel-associated box domain binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 200991_s_at NM_014748 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014748.1 /DEF=Homo sapiens KIAA0064 gene product (KIAA0064), mRNA. /FEA=mRNA /GEN=KIAA0064 /PROD=KIAA0064 gene product /DB_XREF=gi:7661889 /UG=Hs.278569 sorting nexin 17 /FL=gb:BC002524.1 gb:BC002610.1 gb:D31764.1 gb:NM_014748.1" NM_014748 sorting nexin 17 SNX17 9784 NM_001267059 /// NM_001267060 /// NM_001267061 /// NM_014748 /// NR_049782 /// NR_049783 /// NR_049784 /// NR_049785 /// NR_049786 /// NR_049787 /// NR_049788 /// XM_006712154 0001525 // angiogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006707 // cholesterol catabolic process // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from electronic annotation /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030100 // regulation of endocytosis // non-traceable author statement /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0031589 // cell-substrate adhesion // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060996 // dendritic spine development // inferred from electronic annotation /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation /// 0061351 // neural precursor cell proliferation // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from direct assay /// 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay" 200992_at AL137335 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL137335.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A179 (from clone DKFZp434A179); partial cds. /FEA=mRNA /GEN=DKFZp434A179 /PROD=hypothetical protein /DB_XREF=gi:6807827 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AL137335 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200993_at AA939270 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA939270 /FEA=EST /DB_XREF=gi:3099183 /DB_XREF=est:oq31b02.s1 /CLONE=IMAGE:1587915 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AA939270 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200994_at BG291787 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG291787 /FEA=EST /DB_XREF=gi:13050002 /DB_XREF=est:602386007F1 /CLONE=IMAGE:4515240 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 BG291787 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200995_at AI741392 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI741392 /FEA=EST /DB_XREF=gi:5109680 /DB_XREF=est:wg27b08.x1 /CLONE=IMAGE:2366295 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AI741392 importin 7 IPO7 10527 NM_006391 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200996_at NM_005721 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005721.2 /DEF=Homo sapiens ARP3 (actin-related protein 3, yeast) homolog (ACTR3), mRNA. /FEA=mRNA /GEN=ACTR3 /PROD=ARP3 (actin-related protein 3, yeast) homolog /DB_XREF=gi:7262289 /UG=Hs.5321 ARP3 (actin-related protein 3, yeast) homolog /FL=gb:AF006083.1 gb:NM_005721.2" NM_005721 ARP3 actin-related protein 3 homolog (yeast) ACTR3 10096 NM_001277140 /// NM_005721 /// NR_102318 0006928 // cellular component movement // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0008356 // asymmetric cell division // inferred from electronic annotation /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0033206 // meiotic cytokinesis // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043519 // regulation of myosin II filament organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051321 // meiotic cell cycle // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0051653 // spindle localization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200997_at NM_002896 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002896.1 /DEF=Homo sapiens RNA binding motif protein 4 (RBM4), mRNA. /FEA=mRNA /GEN=RBM4 /PROD=RNA binding motif protein 4 /DB_XREF=gi:4506444 /UG=Hs.6106 RNA binding motif protein 4 /FL=gb:BC000307.1 gb:U89505.1 gb:NM_002896.1" NM_002896 RBM14-RBM4 readthrough /// RNA binding motif protein 4 RBM14-RBM4 /// RBM4 5936 /// 100526737 NM_001198843 /// NM_001198844 /// NM_001198845 /// NM_001198846 /// NM_002896 "0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0002190 // cap-independent translational initiation // inferred from direct assay /// 0002192 // IRES-dependent translational initiation // inferred from direct assay /// 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009725 // response to hormone // traceable author statement /// 0016575 // histone deacetylation // inferred from physical interaction /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0032055 // negative regulation of translation in response to stress // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from direct assay /// 0042921 // glucocorticoid receptor signaling pathway // non-traceable author statement /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045947 // negative regulation of translational initiation // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from direct assay /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016592 // mediator complex // non-traceable author statement /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement /// 0035198 // miRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097157 // pre-mRNA intronic binding // inferred from direct assay /// 0097158 // pre-mRNA intronic pyrimidine-rich binding // inferred from direct assay" 200998_s_at AW029619 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW029619 /FEA=EST /DB_XREF=gi:5888375 /DB_XREF=est:wx14e05.x1 /CLONE=IMAGE:2543648 /UG=Hs.74368 transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment /FL=gb:NM_006825.1" AW029619 cytoskeleton-associated protein 4 CKAP4 10970 NM_006825 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 200999_s_at NM_006825 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006825.1 /DEF=Homo sapiens transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment (P63), mRNA. /FEA=mRNA /GEN=P63 /PROD=transmembrane protein (63kD), endoplasmicreticulumGolgi intermediate compartment /DB_XREF=gi:5803112 /UG=Hs.74368 transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment /FL=gb:NM_006825.1" NM_006825 cytoskeleton-associated protein 4 CKAP4 10970 NM_006825 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201000_at NM_001605 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001605.1 /DEF=Homo sapiens alanyl-tRNA synthetase (AARS), mRNA. /FEA=mRNA /GEN=AARS /PROD=alanyl-tRNA synthetase /DB_XREF=gi:4501840 /UG=Hs.75102 alanyl-tRNA synthetase /FL=gb:D32050.1 gb:NM_001605.1" NM_001605 alanyl-tRNA synthetase AARS 16 NM_001605 /// XM_006721153 0001942 // hair follicle development // inferred from electronic annotation /// 0006400 // tRNA modification // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006419 // alanyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008033 // tRNA processing // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0034620 // cellular response to unfolded protein // inferred from electronic annotation /// 0043039 // tRNA aminoacylation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004813 // alanine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201001_s_at BG164064 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG164064 /FEA=EST /DB_XREF=gi:12670767 /DB_XREF=est:602341091F1 /CLONE=IMAGE:4449022 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1 BG164064 transmembrane protein 189 /// TMEM189-UBE2V1 readthrough /// ubiquitin-conjugating enzyme E2 variant 1 /// ubiquitin-conjugating enzyme E2 variant 2 TMEM189 /// TMEM189-UBE2V1 /// UBE2V1 /// UBE2V2 7335 /// 7336 /// 387521 /// 387522 NM_001032288 /// NM_001162505 /// NM_001257393 /// NM_001257394 /// NM_001257395 /// NM_001257396 /// NM_001257397 /// NM_001257398 /// NM_001257399 /// NM_001282575 /// NM_001282576 /// NM_001282577 /// NM_001282578 /// NM_001282579 /// NM_001282580 /// NM_003349 /// NM_003350 /// NM_021988 /// NM_022442 /// NM_199129 /// NM_199144 /// NM_199203 /// NR_027889 /// NR_047554 /// NR_104218 /// XM_005251300 "0000209 // protein polyubiquitination // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay" 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201002_s_at U39361 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U39361.1 /DEF=Homo sapiens DNA-binding protein (CROC-1B) mRNA, complete cds. /FEA=mRNA /GEN=CROC-1B /PROD=DNA-binding protein /DB_XREF=gi:1066081 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1" U39361 transmembrane protein 189 /// TMEM189-UBE2V1 readthrough /// ubiquitin-conjugating enzyme E2 variant 1 /// ubiquitin-conjugating enzyme E2 variant 2 TMEM189 /// TMEM189-UBE2V1 /// UBE2V1 /// UBE2V2 7335 /// 7336 /// 387521 /// 387522 NM_001032288 /// NM_001162505 /// NM_001257393 /// NM_001257394 /// NM_001257395 /// NM_001257396 /// NM_001257397 /// NM_001257398 /// NM_001257399 /// NM_001282575 /// NM_001282576 /// NM_001282577 /// NM_001282578 /// NM_001282579 /// NM_001282580 /// NM_003349 /// NM_003350 /// NM_021988 /// NM_022442 /// NM_199129 /// NM_199144 /// NM_199203 /// NR_027889 /// NR_047554 /// NR_104218 /// XM_005251300 "0000209 // protein polyubiquitination // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay" 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201003_x_at NM_003349 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003349.2 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1), transcript variant 2, mRNA. /FEA=mRNA /GEN=UBE2V1 /PROD=ubiquitin-conjugating enzyme E2 variant 1,isoform b /DB_XREF=gi:12025659 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1" NM_003349 transmembrane protein 189 /// TMEM189-UBE2V1 readthrough /// ubiquitin-conjugating enzyme E2 variant 1 /// ubiquitin-conjugating enzyme E2 variant 2 TMEM189 /// TMEM189-UBE2V1 /// UBE2V1 /// UBE2V2 7335 /// 7336 /// 387521 /// 387522 NM_001032288 /// NM_001162505 /// NM_001257393 /// NM_001257394 /// NM_001257395 /// NM_001257396 /// NM_001257397 /// NM_001257398 /// NM_001257399 /// NM_001282575 /// NM_001282576 /// NM_001282577 /// NM_001282578 /// NM_001282579 /// NM_001282580 /// NM_003349 /// NM_003350 /// NM_021988 /// NM_022442 /// NM_199129 /// NM_199144 /// NM_199203 /// NR_027889 /// NR_047554 /// NR_104218 /// XM_005251300 "0000209 // protein polyubiquitination // traceable author statement /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0030154 // cell differentiation // non-traceable author statement /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay" 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201004_at NM_006280 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006280.1 /DEF=Homo sapiens signal sequence receptor, delta (translocon-associated protein delta) (SSR4), mRNA. /FEA=mRNA /GEN=SSR4 /PROD=signal sequence receptor, delta /DB_XREF=gi:5454089 /UG=Hs.102135 signal sequence receptor, delta (translocon-associated protein delta) /FL=gb:BC003371.1 gb:NM_006280.1" NM_006280 "signal sequence receptor, delta" SSR4 6748 NM_001204526 /// NM_001204527 /// NM_006280 /// NR_037927 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006886 // intracellular protein transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005784 // Sec61 translocon complex // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // non-traceable author statement 201005_at NM_001769 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001769.1 /DEF=Homo sapiens CD9 antigen (p24) (CD9), mRNA. /FEA=mRNA /GEN=CD9 /PROD=CD9 antigen (p24) /DB_XREF=gi:4502692 /UG=Hs.1244 CD9 antigen (p24) /FL=gb:M38690.1 gb:NM_001769.1 gb:L34068.1" NM_001769 CD9 molecule CD9 928 NM_001769 /// XM_005253814 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007338 // single fertilization // traceable author statement /// 0007342 // fusion of sperm to egg plasma membrane // inferred from direct assay /// 0007342 // fusion of sperm to egg plasma membrane // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009414 // response to water deprivation // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030913 // paranodal junction assembly // inferred from sequence or structural similarity /// 0032504 // multicellular organism reproduction // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201006_at NM_005809 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005809.1 /DEF=Homo sapiens peroxiredoxin 2 (PRDX2), mRNA. /FEA=mRNA /GEN=PRDX2 /PROD=peroxiredoxin 2 /DB_XREF=gi:5902725 /UG=Hs.146354 peroxiredoxin 2 /FL=gb:BC000452.1 gb:BC003022.1 gb:NM_005809.1" NM_005809 peroxiredoxin 2 PRDX2 7001 NM_005809 /// NM_181737 /// NM_181738 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0006979 // response to oxidative stress // non-traceable author statement /// 0019430 // removal of superoxide radicals // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008379 // thioredoxin peroxidase activity // traceable author statement /// 0016209 // antioxidant activity // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201007_at NM_000183 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000183.1 /DEF=Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (HADHB), mRNA. /FEA=mRNA /GEN=HADHB /PROD=hydroxyacyl-Coenzyme Adehydrogenase3-ketoacyl-Coenzyme Athiolaseenoyl-Coenzyme A hydratase (trifunctionalprotein), beta subunit /DB_XREF=gi:4504326 /UG=Hs.146812 hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), beta subunit /FL=gb:AF113209.1 gb:NM_000183.1 gb:D16481.1" NM_000183 "hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit" HADHB 3032 NM_000183 /// NM_001281512 /// NM_001281513 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // non-traceable author statement /// 0005740 // mitochondrial envelope // traceable author statement /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016507 // mitochondrial fatty acid beta-oxidation multienzyme complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016508 // long-chain-enoyl-CoA hydratase activity // inferred from electronic annotation /// 0016509 // long-chain-3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051287 // NAD binding // inferred from electronic annotation" 201008_s_at AA812232 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA812232 /FEA=EST /DB_XREF=gi:2881843 /DB_XREF=est:ob84h09.s1 /CLONE=IMAGE:1338113 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1" AA812232 thioredoxin interacting protein TXNIP 10628 NM_006472 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0071228 // cellular response to tumor cell // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201009_s_at AI439556 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI439556 /FEA=EST /DB_XREF=gi:4305149 /DB_XREF=est:tc90c12.x1 /CLONE=IMAGE:2073430 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1" AI439556 thioredoxin interacting protein TXNIP 10628 NM_006472 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0071228 // cellular response to tumor cell // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201010_s_at NM_006472 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006472.1 /DEF=Homo sapiens upregulated by 1,25-dihydroxyvitamin D-3 (VDUP1), mRNA. /FEA=mRNA /GEN=VDUP1 /PROD=upregulated by 1,25-dihydroxyvitamin D-3 /DB_XREF=gi:5454161 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1" NM_006472 thioredoxin interacting protein TXNIP 10628 NM_006472 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0071228 // cellular response to tumor cell // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201011_at NM_002950 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002950.1 /DEF=Homo sapiens ribophorin I (RPN1), mRNA. /FEA=mRNA /GEN=RPN1 /PROD=ribophorin I /DB_XREF=gi:4506674 /UG=Hs.2280 ribophorin I /FL=gb:NM_002950.1" NM_002950 ribophorin I RPN1 6184 NM_002950 0006412 // translation // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation "0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201012_at NM_000700 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000700.1 /DEF=Homo sapiens annexin A1 (ANXA1), mRNA. /FEA=mRNA /GEN=ANXA1 /PROD=annexin I /DB_XREF=gi:4502100 /UG=Hs.78225 annexin A1 /FL=gb:BC001275.1 gb:NM_000700.1" NM_000700 annexin A1 ANXA1 301 NM_000700 0001780 // neutrophil homeostasis // inferred from mutant phenotype /// 0002674 // negative regulation of acute inflammatory response // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033031 // positive regulation of neutrophil apoptotic process // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046632 // alpha-beta T cell differentiation // inferred from sequence or structural similarity /// 0050482 // arachidonic acid secretion // inferred from electronic annotation /// 0050709 // negative regulation of protein secretion // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060206 // estrous cycle phase // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0071385 // cellular response to glucocorticoid stimulus // inferred from direct assay /// 0097350 // neutrophil clearance // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000483 // negative regulation of interleukin-8 secretion // inferred from mutant phenotype 0001533 // cornified envelope // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005198 // structural molecule activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction" 201013_s_at AA902652 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA902652 /FEA=EST /DB_XREF=gi:3037775 /DB_XREF=est:ok71a12.s1 /CLONE=IMAGE:1519390 /UG=Hs.117950 multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase /FL=gb:NM_006452.1 AA902652 "phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase" PAICS 10606 NM_001079524 /// NM_001079525 /// NM_006452 /// XM_006714035 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // traceable author statement /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004638 // phosphoribosylaminoimidazole carboxylase activity // traceable author statement /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034023 // 5-(carboxyamino)imidazole ribonucleotide mutase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201014_s_at NM_006452 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006452.1 /DEF=Homo sapiens multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase (ADE2H1), mRNA. /FEA=mRNA /GEN=ADE2H1 /PROD=multifunctional polypeptide similar to SAICARsynthetase and AIR carboxylase /DB_XREF=gi:5453538 /UG=Hs.117950 multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase /FL=gb:NM_006452.1" NM_006452 "phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase" PAICS 10606 NM_001079524 /// NM_001079525 /// NM_006452 /// XM_006714035 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009113 // purine nucleobase biosynthetic process // traceable author statement /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004638 // phosphoribosylaminoimidazole carboxylase activity // traceable author statement /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034023 // 5-(carboxyamino)imidazole ribonucleotide mutase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201015_s_at NM_021991 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021991.1 /DEF=Homo sapiens junction plakoglobin (JUP), transcript variant 2, mRNA. /FEA=mRNA /GEN=JUP /PROD=junction plakoglobin, isoform 1 /DB_XREF=gi:12056467 /UG=Hs.2340 junction plakoglobin /FL=gb:NM_021991.1 gb:BC000441.1" NM_021991 junction plakoglobin JUP 3728 NM_002230 /// NM_021991 /// XM_005257313 /// XM_006721871 /// XM_006721872 /// XM_006721873 /// XM_006721874 /// XM_006721875 /// XM_006721876 /// XM_006721877 /// XM_006721878 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000902 // cell morphogenesis // not recorded /// 0002159 // desmosome assembly // inferred from direct assay /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0003136 // negative regulation of heart induction by canonical Wnt signaling pathway // not recorded /// 0003181 // atrioventricular valve morphogenesis // not recorded /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007369 // gastrulation // not recorded /// 0007398 // ectoderm development // not recorded /// 0007399 // nervous system development // not recorded /// 0016331 // morphogenesis of embryonic epithelium // not recorded /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0043588 // skin development // not recorded /// 0045216 // cell-cell junction organization // traceable author statement /// 0048599 // oocyte development // not recorded /// 0050982 // detection of mechanical stimulus // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071603 // endothelial cell-cell adhesion // inferred from sequence or structural similarity /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred by curator 0005634 // nucleus // inferred from mutant phenotype /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005915 // zonula adherens // not recorded /// 0005915 // zonula adherens // inferred from sequence or structural similarity /// 0005916 // fascia adherens // not recorded /// 0009898 // cytoplasmic side of plasma membrane // not recorded /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // not recorded /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030018 // Z disc // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from sequence or structural similarity /// 0030057 // desmosome // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071665 // gamma-catenin-TCF7L2 complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005198 // structural molecule activity // not recorded /// 0005198 // structural molecule activity // non-traceable author statement /// 0005199 // structural constituent of cell wall // inferred by curator /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction 201016_at BE542684 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE542684 /FEA=EST /DB_XREF=gi:9771329 /DB_XREF=est:601067180F1 /CLONE=IMAGE:3453571 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 BE542684 "eukaryotic translation initiation factor 1A, X-linked" EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement "0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201017_at BG149698 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG149698 /FEA=EST /DB_XREF=gi:12661728 /DB_XREF=est:nad32e01.x1 /CLONE=IMAGE:3367368 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 BG149698 "eukaryotic translation initiation factor 1A, X-linked" EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement "0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201018_at AL079283 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL079283.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 39515. /FEA=mRNA /DB_XREF=gi:5102744 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 AL079283 "eukaryotic translation initiation factor 1A, X-linked" EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement "0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201019_s_at NM_001412 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001412.1 /DEF=Homo sapiens eukaryotic translation initiation factor 1A (EIF1A), mRNA. /FEA=mRNA /GEN=EIF1A /PROD=eukaryotic translation initiation factor 1A /DB_XREF=gi:4503498 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1" NM_001412 "eukaryotic translation initiation factor 1A, X-linked" EIF1AX 1964 NM_001412 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005829 // cytosol // traceable author statement "0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201020_at NM_003405 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003405.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, eta polypeptide (YWHAH), mRNA. /FEA=mRNA /GEN=YWHAH /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, eta polypeptide /DB_XREF=gi:4507950 /UG=Hs.75544 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, eta polypeptide /FL=gb:BC003047.1 gb:L20422.1 gb:NM_003405.1" NM_003405 "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta" YWHAH 7533 NM_003405 "0002028 // regulation of sodium ion transport // inferred from direct assay /// 0006713 // glucocorticoid catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0045664 // regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0086010 // membrane depolarization during action potential // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000649 // regulation of sodium ion transmembrane transporter activity // inferred from direct assay" 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0014704 // intercalated disc // inferred by curator /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005159 // insulin-like growth factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017080 // sodium channel regulator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from sequence or structural similarity /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201021_s_at BF697964 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF697964 /FEA=EST /DB_XREF=gi:11983372 /DB_XREF=est:602130050F1 /CLONE=IMAGE:4286556 /UG=Hs.82306 destrin (actin depolymerizing factor) /FL=gb:NM_006870.2 BF697964 destrin (actin depolymerizing factor) DSTN 11034 NM_001011546 /// NM_006870 0000910 // cytokinesis // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0030042 // actin filament depolymerization // inferred from electronic annotation /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0051014 // actin filament severing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 201022_s_at NM_006870 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006870.2 /DEF=Homo sapiens destrin (actin depolymerizing factor) (ADF), mRNA. /FEA=mRNA /GEN=ADF /PROD=destrin (actin depolymerizing factor) /DB_XREF=gi:6466447 /UG=Hs.82306 destrin (actin depolymerizing factor) /FL=gb:NM_006870.2" NM_006870 destrin (actin depolymerizing factor) DSTN 11034 NM_001011546 /// NM_006870 0000910 // cytokinesis // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0030042 // actin filament depolymerization // inferred from electronic annotation /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0051014 // actin filament severing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 201023_at NM_005642 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005642.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD (TAF2F), mRNA. /FEA=mRNA /GEN=TAF2F /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, F, 55kD /DB_XREF=gi:5032148 /UG=Hs.155188 TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD /FL=gb:NM_005642.1 gb:U18062.1" NM_005642 "TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa" TAF7 6879 NM_005642 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000296 // spermine transport // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction 201024_x_at BG261322 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG261322 /FEA=EST /DB_XREF=gi:12771138 /DB_XREF=est:602373079F1 /CLONE=IMAGE:4484563 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 BG261322 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201025_at AB018284 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB018284.1 /DEF=Homo sapiens mRNA for KIAA0741 protein, complete cds. /FEA=mRNA /GEN=KIAA0741 /PROD=KIAA0741 protein /DB_XREF=gi:3882202 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1" AB018284 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201026_at AB018284 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB018284.1 /DEF=Homo sapiens mRNA for KIAA0741 protein, complete cds. /FEA=mRNA /GEN=KIAA0741 /PROD=KIAA0741 protein /DB_XREF=gi:3882202 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1" AB018284 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201027_s_at NM_015904 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015904.1 /DEF=Homo sapiens KIAA0741 gene product (IF2), mRNA. /FEA=mRNA /GEN=IF2 /PROD=translation initiation factor IF2 /DB_XREF=gi:7706231 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1" NM_015904 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 /// XM_005264075 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201028_s_at U82164 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U82164.1 /DEF=Human transmembrane protein CD99 type II mRNA, complete cds. /FEA=mRNA /GEN=CD99 /PROD=CD99 typeII /DB_XREF=gi:2149134 /UG=Hs.177543 antigen identified by monoclonal antibodies 12E7, F21 and O13 /FL=gb:BC002584.1 gb:BC003147.1 gb:M16279.1 gb:U82164.1 gb:NM_002414.1" U82164 CD99 molecule CD99 4267 NM_001122898 /// NM_001277710 /// NM_002414 /// XM_005274530 /// XM_005274532 /// XM_005274533 /// XM_005274534 /// XM_005274535 /// XM_005274794 /// XM_005274796 /// XM_005274797 /// XM_005274798 /// XM_005274799 /// XM_006724489 /// XM_006724490 /// XM_006724491 /// XM_006724870 /// XM_006724871 /// XM_006724872 0007155 // cell adhesion // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201029_s_at NM_002414 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002414.1 /DEF=Homo sapiens antigen identified by monoclonal antibodies 12E7, F21 and O13 (MIC2), mRNA. /FEA=mRNA /GEN=MIC2 /PROD=antigen identified by monoclonal antibodies12E7, F21 and O13 /DB_XREF=gi:4505182 /UG=Hs.177543 antigen identified by monoclonal antibodies 12E7, F21 and O13 /FL=gb:BC002584.1 gb:BC003147.1 gb:M16279.1 gb:U82164.1 gb:NM_002414.1" NM_002414 CD99 molecule CD99 4267 NM_001122898 /// NM_001277710 /// NM_002414 /// XM_005274530 /// XM_005274532 /// XM_005274533 /// XM_005274534 /// XM_005274535 /// XM_005274794 /// XM_005274796 /// XM_005274797 /// XM_005274798 /// XM_005274799 /// XM_006724489 /// XM_006724490 /// XM_006724491 /// XM_006724870 /// XM_006724871 /// XM_006724872 0007155 // cell adhesion // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201030_x_at NM_002300 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002300.1 /DEF=Homo sapiens lactate dehydrogenase B (LDHB), mRNA. /FEA=mRNA /GEN=LDHB /PROD=lactate dehydrogenase B /DB_XREF=gi:4557031 /UG=Hs.234489 lactate dehydrogenase B /FL=gb:BC002362.1 gb:NM_002300.1" NM_002300 lactate dehydrogenase B LDHB 3945 NM_001174097 /// NM_002300 /// XM_006719074 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004457 // lactate dehydrogenase activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201031_s_at NM_005520 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005520.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein H1 (H) (HNRPH1), mRNA. /FEA=mRNA /GEN=HNRPH1 /PROD=heterogeneous nuclear ribonucleoprotein H1 (H) /DB_XREF=gi:5031752 /UG=Hs.245710 heterogeneous nuclear ribonucleoprotein H1 (H) /FL=gb:BC001348.1 gb:L22009.1 gb:NM_005520.1" NM_005520 heterogeneous nuclear ribonucleoprotein H1 (H) HNRNPH1 3187 NM_001257293 /// NM_005520 /// XM_005265895 /// XM_005265896 /// XM_005265901 /// XM_005265902 /// XM_005265903 /// XM_006714862 /// XM_006714863 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from direct assay" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201032_at NM_006698 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006698.1 /DEF=Homo sapiens bladder cancer associated protein (BLCAP), mRNA. /FEA=mRNA /GEN=BLCAP /PROD=bladder cancer associated protein /DB_XREF=gi:5729737 /UG=Hs.5300 bladder cancer associated protein /FL=gb:AF053470.1 gb:NM_006698.1" NM_006698 bladder cancer associated protein BLCAP 10904 NM_001167820 /// NM_001167821 /// NM_001167822 /// NM_001167823 /// NM_006698 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0030262 // apoptotic nuclear changes // inferred from direct assay 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201033_x_at NM_001002 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001002.1 /DEF=Homo sapiens ribosomal protein, large, P0 (RPLP0), mRNA. /FEA=mRNA /GEN=RPLP0 /PROD=ribosomal protein, large, P0 /DB_XREF=gi:4506666 /UG=Hs.73742 ribosomal protein, large, P0 /FL=gb:BC000345.1 gb:BC000752.1 gb:BC001127.1 gb:AF274958.1 gb:BC001834.1 gb:M17885.1 gb:NM_001002.1" NM_001002 "ribosomal protein, large, P0" RPLP0 6175 NM_001002 /// NM_053275 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201034_at BE545756 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE545756 /FEA=EST /DB_XREF=gi:9774401 /DB_XREF=est:601076920F1 /CLONE=IMAGE:3462940 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1" BE545756 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 /// XM_005269529 /// XM_005269530 /// XM_005269531 /// XM_005269533 /// XM_005269534 /// XM_005269535 /// XM_006717626 /// XM_006717627 /// XM_006717628 /// XM_006717629 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 201035_s_at BC000306 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000306.1 /DEF=Homo sapiens, L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain, clone MGC:8392, mRNA, complete cds. /FEA=mRNA /PROD=L-3-hydroxyacyl-Coenzyme A dehydrogenase, shortchain /DB_XREF=gi:12653080 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1" BC000306 hydroxyacyl-CoA dehydrogenase HADH 3033 NM_001184705 /// NM_005327 /// XM_005262972 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement "0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation" 201036_s_at NM_005327 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005327.1 /DEF=Homo sapiens L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain (HADHSC), mRNA. /FEA=mRNA /GEN=HADHSC /PROD=L-3-hydroxyacyl-Coenzyme A dehydrogenase, shortchain /DB_XREF=gi:4885386 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1" NM_005327 hydroxyacyl-CoA dehydrogenase HADH 3033 NM_001184705 /// NM_005327 /// XM_005262972 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement "0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation" 201037_at NM_002627 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002627.1 /DEF=Homo sapiens phosphofructokinase, platelet (PFKP), mRNA. /FEA=mRNA /GEN=PFKP /PROD=phosphofructokinase, platelet /DB_XREF=gi:11321600 /UG=Hs.99910 phosphofructokinase, platelet /FL=gb:NM_002627.1 gb:BC002536.1 gb:M64784.1 gb:D25328.1" NM_002627 "phosphofructokinase, platelet" PFKP 5214 NM_001242339 /// NM_002627 /// XM_005252465 /// XM_005252466 /// XM_005252467 /// XM_006717449 0005975 // carbohydrate metabolic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from sequence or structural similarity /// 0046835 // carbohydrate phosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005945 // 6-phosphofructokinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from sequence or structural similarity /// 0003872 // 6-phosphofructokinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201038_s_at T67821 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:T67821 /FEA=EST /DB_XREF=gi:678969 /DB_XREF=est:yc39d08.s1 /CLONE=IMAGE:83055 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 T67821 "acidic (leucine-rich) nuclear phosphoprotein 32 family, member A" ANP32A 8125 NM_006305 /// XM_006720707 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201039_s_at BF572938 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF572938 /FEA=EST /DB_XREF=gi:11646661 /DB_XREF=est:602078949F2 /CLONE=IMAGE:4253100 /UG=Hs.180455 RAD23 (S. cerevisiae) homolog A /FL=gb:NM_005053.1 gb:D21235.1 BF572938 RAD23 homolog A (S. cerevisiae) RAD23A 5886 NM_001270362 /// NM_001270363 /// NM_005053 /// NR_072976 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 201040_at NM_002070 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002070.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (GNAI2), mRNA. /FEA=mRNA /GEN=GNAI2 /PROD=guanine nucleotide binding protein (G protein),alpha inhibiting activity polypeptide 2 /DB_XREF=gi:4504040 /UG=Hs.77269 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 /FL=gb:J03004.1 gb:NM_002070.1" NM_002070 "guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2" GNAI2 2771 NM_001166425 /// NM_001282617 /// NM_001282618 /// NM_001282619 /// NM_001282620 /// NM_002070 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001973 // adenosine receptor signaling pathway // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007584 // response to nutrient // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 201041_s_at NM_004417 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004417.2 /DEF=Homo sapiens dual specificity phosphatase 1 (DUSP1), mRNA. /FEA=mRNA /GEN=DUSP1 /PROD=dual specificity phosphatase 1 /DB_XREF=gi:7108342 /UG=Hs.171695 dual specificity phosphatase 1 /FL=gb:NM_004417.2" NM_004417 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051447 // negative regulation of meiotic cell cycle // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // /// 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from sequence or structural similarity 201042_at AL031651 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL031651 /DEF=Human DNA sequence from clone RP5-1054A22 on chromosome 20q11.22-12 Contains two isoforms of the gene for TGM2 (transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), ESTs, STSs, GSSs and a CpG island /FEA=mRNA_1 /DB_XREF=gi:6065866 /UG=Hs.8265 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) /FL=gb:M55153.1 gb:NM_004613.1" AL031651 transglutaminase 2 TGM2 7052 NM_004613 /// NM_198951 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018153 // isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine // inferred from electronic annotation /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0051561 // positive regulation of mitochondrial calcium ion concentration // inferred from mutant phenotype /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from mutant phenotype /// 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201043_s_at NM_006305 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006305.1 /DEF=Homo sapiens putative human HLA class II associated protein I (PHAP1), mRNA. /FEA=mRNA /GEN=PHAP1 /PROD=putative human HLA class II associated proteinI /DB_XREF=gi:5453879 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1" NM_006305 "acidic (leucine-rich) nuclear phosphoprotein 32 family, member A" ANP32A 8125 NM_006305 /// XM_006720707 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201044_x_at AA530892 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA530892 /FEA=EST /DB_XREF=gi:2273598 /DB_XREF=est:ni97d11.s1 /CLONE=IMAGE:984789 /UG=Hs.171695 dual specificity phosphatase 1 /FL=gb:NM_004417.2 AA530892 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051447 // negative regulation of meiotic cell cycle // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // /// 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from sequence or structural similarity 201045_s_at BF513857 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF513857 /FEA=EST /DB_XREF=gi:11599036 /DB_XREF=est:UI-H-BW1-amz-e-01-0-UI.s1 /CLONE=IMAGE:3071689 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1" BF513857 "RAB6A, member RAS oncogene family /// RAB6C-like" RAB6A /// WTH3DI 5870 /// 150786 NM_001077637 /// NM_001243718 /// NM_001243719 /// NM_002869 /// NM_198896 "0000042 // protein targeting to Golgi // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from direct assay /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0022402 // cell cycle process // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0072385 // minus-end-directed organelle transport along microtubule // traceable author statement" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 201046_s_at NM_005053 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005053.1 /DEF=Homo sapiens RAD23 (S. cerevisiae) homolog A (RAD23A), mRNA. /FEA=mRNA /GEN=RAD23A /PROD=RAD23 (S. cerevisiae) homolog A /DB_XREF=gi:4826963 /UG=Hs.180455 RAD23 (S. cerevisiae) homolog A /FL=gb:NM_005053.1 gb:D21235.1" NM_005053 RAD23 homolog A (S. cerevisiae) RAD23A 5886 NM_001270362 /// NM_001270363 /// NM_005053 /// NR_072976 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 1990381 // ubiquitin-specific protease binding // inferred from physical interaction 201047_x_at BC003617 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003617.1 /DEF=Homo sapiens, RAB6, member RAS oncogene family, clone MGC:1654, mRNA, complete cds. /FEA=mRNA /PROD=RAB6, member RAS oncogene family /DB_XREF=gi:13177663 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1" BC003617 "RAB6A, member RAS oncogene family /// RAB6C-like" RAB6A /// WTH3DI 5870 /// 150786 NM_001077637 /// NM_001243718 /// NM_001243719 /// NM_002869 /// NM_198896 "0000042 // protein targeting to Golgi // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from direct assay /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0022402 // cell cycle process // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0072385 // minus-end-directed organelle transport along microtubule // traceable author statement" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 201048_x_at NM_002869 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002869.1 /DEF=Homo sapiens RAB6, member RAS oncogene family (RAB6), mRNA. /FEA=mRNA /GEN=RAB6 /PROD=RAB6, member RAS oncogene family /DB_XREF=gi:4506372 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1" NM_002869 "RAB6A, member RAS oncogene family /// RAB6C-like" RAB6A /// WTH3DI 5870 /// 150786 NM_001077637 /// NM_001243718 /// NM_001243719 /// NM_002869 /// NM_198896 "0000042 // protein targeting to Golgi // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010824 // regulation of centrosome duplication // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018125 // peptidyl-cysteine methylation // inferred from direct assay /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0022402 // cell cycle process // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0072385 // minus-end-directed organelle transport along microtubule // traceable author statement" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction 201049_s_at NM_022551 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022551.1 /DEF=Homo sapiens ribosomal protein S18 (RPS18), mRNA. /FEA=mRNA /GEN=RPS18 /PROD=ribosomal protein S18 /DB_XREF=gi:11968181 /UG=Hs.275865 ribosomal protein S18 /FL=gb:NM_022551.1" NM_022551 ribosomal protein S18 RPS18 6222 NM_022551 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042254 // ribosome biogenesis // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement" 0005581 // collagen trimer // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // not recorded /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201050_at NM_012268 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012268.1 /DEF=Homo sapiens similar to vaccinia virus HindIII K4L ORF (HU-K4), mRNA. /FEA=mRNA /GEN=HU-K4 /PROD=similar to vaccinia virus HindIII K4L ORF /DB_XREF=gi:7110640 /UG=Hs.74573 similar to vaccinia virus HindIII K4L ORF /FL=gb:BC000553.1 gb:U60644.1 gb:NM_012268.1" NM_012268 "phospholipase D family, member 3" PLD3 23646 NM_001031696 /// NM_001291311 /// NM_012268 /// XM_005258704 /// XM_005258705 /// XM_005258706 /// XM_005258707 /// XM_005258708 /// XM_005258709 /// XM_005258710 /// XM_006723121 /// XM_006723122 /// XM_006723123 /// XM_006723124 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006655 // phosphatidylglycerol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070290 // N-acylphosphatidylethanolamine-specific phospholipase D activity // inferred from electronic annotation 201051_at BE560202 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE560202 /FEA=EST /DB_XREF=gi:9803834 /DB_XREF=est:601347428F1 /CLONE=IMAGE:3688350 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 BE560202 "acidic (leucine-rich) nuclear phosphoprotein 32 family, member A" ANP32A 8125 NM_006305 /// XM_006720707 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201052_s_at BG029917 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG029917 /FEA=EST /DB_XREF=gi:12419014 /DB_XREF=est:602297261F1 /CLONE=IMAGE:4391534 /UG=Hs.75925 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) /FL=gb:D88378.1 gb:NM_006814.1" BG029917 "proteasome (prosome, macropain) inhibitor subunit 1 (PI31)" PSMF1 9491 NM_006814 /// NM_178578 /// NM_178579 /// XM_005260873 /// XM_005260874 /// XM_006723664 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 1901799 // negative regulation of proteasomal protein catabolic process // inferred from direct assay" 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 201053_s_at NM_006814 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006814.1 /DEF=Homo sapiens proteasome (prosome, macropain) inhibitor subunit 1 (PI31) (PSMF1), mRNA. /FEA=mRNA /GEN=PSMF1 /PROD=proteasome inhibitor /DB_XREF=gi:5803122 /UG=Hs.75925 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) /FL=gb:D88378.1 gb:NM_006814.1" NM_006814 "proteasome (prosome, macropain) inhibitor subunit 1 (PI31)" PSMF1 9491 NM_006814 /// NM_178578 /// NM_178579 /// XM_005260873 /// XM_005260874 /// XM_006723664 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 1901799 // negative regulation of proteasomal protein catabolic process // inferred from direct assay" 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0004866 // endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 201054_at BE966599 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE966599 /FEA=EST /DB_XREF=gi:11772191 /DB_XREF=est:601660283R1 /CLONE=IMAGE:3906044 /UG=Hs.77492 heterogeneous nuclear ribonucleoprotein A0 /FL=gb:BC001008.1 gb:NM_006805.1 gb:U23803.1 BE966599 heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 10949 NM_006805 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201055_s_at NM_006805 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006805.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein A0 (HNRPA0), mRNA. /FEA=mRNA /GEN=HNRPA0 /PROD=heterogeneous nuclear ribonucleoprotein A0 /DB_XREF=gi:5803035 /UG=Hs.77492 heterogeneous nuclear ribonucleoprotein A0 /FL=gb:BC001008.1 gb:NM_006805.1 gb:U23803.1" NM_006805 heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 10949 NM_006805 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from sequence or structural similarity /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201056_at N53479 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N53479 /FEA=EST /DB_XREF=gi:1194645 /DB_XREF=est:yv42c11.s1 /CLONE=IMAGE:245396 /UG=Hs.7844 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 /FL=gb:NM_004487.1" N53479 golgin B1 GOLGB1 2804 NM_001256486 /// NM_001256487 /// NM_001256488 /// NM_004487 /// XM_005247371 /// XM_005247372 /// XM_005247373 /// XM_006713587 /// XM_006713588 /// XM_006713589 /// XM_006713590 /// XM_006713591 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007030 // Golgi organization // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201057_s_at NM_004487 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004487.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 (GOLGB1), mRNA. /FEA=mRNA /GEN=GOLGB1 /PROD=golgi autoantigen, golgin subfamily b,macrogolgin (with transmembrane signal), 1 /DB_XREF=gi:4758453 /UG=Hs.7844 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 /FL=gb:NM_004487.1" NM_004487 golgin B1 GOLGB1 2804 NM_001256486 /// NM_001256487 /// NM_001256488 /// NM_004487 /// XM_005247371 /// XM_005247372 /// XM_005247373 /// XM_006713587 /// XM_006713588 /// XM_006713589 /// XM_006713590 /// XM_006713591 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007030 // Golgi organization // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201058_s_at NM_006097 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006097.1 /DEF=Homo sapiens myosin regulatory light chain 2, smooth muscle isoform (MYRL2), mRNA. /FEA=mRNA /GEN=MYRL2 /PROD=myosin regulatory light chain 2, smooth muscleisoform /DB_XREF=gi:5174602 /UG=Hs.9615 myosin regulatory light chain 2, smooth muscle isoform /FL=gb:J02854.1 gb:NM_006097.1" NM_006097 "myosin, light chain 9, regulatory" MYL9 10398 NM_006097 /// NM_181526 0006936 // muscle contraction // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007411 // axon guidance // traceable author statement 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201059_at NM_005231 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005231.1 /DEF=Homo sapiens ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) (EMS1), mRNA. /FEA=mRNA /GEN=EMS1 /PROD=cortactin /DB_XREF=gi:4885204 /UG=Hs.119257 ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) /FL=gb:M98343.1 gb:NM_005231.1" NM_005231 cortactin CTTN 2017 NM_001184740 /// NM_005231 /// NM_138565 /// XM_006718447 /// XM_006718448 0001726 // ruffle // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201060_x_at AI537887 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI537887 /FEA=EST /DB_XREF=gi:4452022 /DB_XREF=est:tp32g06.x1 /CLONE=IMAGE:2189530 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1 AI537887 stomatin STOM 2040 NM_001270526 /// NM_001270527 /// NM_004099 /// NM_198194 /// NR_073037 0051260 // protein homooligomerization // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 201061_s_at M81635 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M81635.1 /DEF=Homo sapiens erythrocyte membrane protein mRNA, complete cds. /FEA=mRNA /GEN=stomatin peptide /PROD=stomatin peptide /DB_XREF=gi:181183 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1" M81635 stomatin STOM 2040 NM_001270526 /// NM_001270527 /// NM_004099 /// NM_198194 /// NR_073037 0051260 // protein homooligomerization // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 201062_at M81635 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M81635.1 /DEF=Homo sapiens erythrocyte membrane protein mRNA, complete cds. /FEA=mRNA /GEN=stomatin peptide /PROD=stomatin peptide /DB_XREF=gi:181183 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1" M81635 stomatin STOM 2040 NM_001270526 /// NM_001270527 /// NM_004099 /// NM_198194 /// NR_073037 0051260 // protein homooligomerization // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0042802 // identical protein binding // inferred from electronic annotation 201063_at NM_002901 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002901.1 /DEF=Homo sapiens reticulocalbin 1, EF-hand calcium binding domain (RCN1), mRNA. /FEA=mRNA /GEN=RCN1 /PROD=reticulocalbin 1 precursor /DB_XREF=gi:4506454 /UG=Hs.167791 reticulocalbin 1, EF-hand calcium binding domain /FL=gb:D42073.1 gb:NM_002901.1" NM_002901 "reticulocalbin 1, EF-hand calcium binding domain" RCN1 5954 NM_002901 0001701 // in utero embryonic development // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201064_s_at NM_003819 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003819.2 /DEF=Homo sapiens poly(A)-binding protein, cytoplasmic 4 (inducible form) (PABPC4), mRNA. /FEA=mRNA /GEN=PABPC4 /PROD=poly(A)-binding protein, cytoplasmic 4(inducible form) /DB_XREF=gi:6552335 /UG=Hs.169900 poly(A)-binding protein, cytoplasmic 4 (inducible form) /FL=gb:NM_003819.2" NM_003819 "polyadenylate-binding protein 4-like /// poly(A) binding protein, cytoplasmic 4 (inducible form)" LOC100996696 /// PABPC4 8761 /// 100996696 NM_001135653 /// NM_001135654 /// NM_003819 /// XM_005269266 /// XM_005275723 /// XM_005276424 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0007596 // blood coagulation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0017130 // poly(C) RNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201065_s_at NM_001518 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001518.1 /DEF=Homo sapiens general transcription factor II, i (GTF2I), mRNA. /FEA=mRNA /GEN=GTF2I /PROD=general transcription factor II, i /DB_XREF=gi:4504202 /UG=Hs.278589 general transcription factor II, i /FL=gb:U77948.1 gb:AF015553.1 gb:AF038969.1 gb:NM_001518.1" NM_001518 "general transcription factor IIi /// general transcription factor IIi, pseudogene 1 /// general transcription factor II, i, pseudogene" GTF2I /// GTF2IP1 /// LOC100093631 2969 /// 2970 /// 100093631 NM_001163636 /// NM_001280800 /// NM_001518 /// NM_032999 /// NM_033000 /// NM_033001 /// NR_002206 /// NR_003580 /// XM_005250291 /// XM_005250296 /// XM_006715939 /// XM_006715940 /// XM_006715941 /// XM_006715942 /// XM_006715943 /// XM_006715944 /// XM_006715945 /// XM_006715946 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation 201066_at NM_001916 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001916.1 /DEF=Homo sapiens cytochrome c-1 (CYC1), mRNA. /FEA=mRNA /GEN=CYC1 /PROD=cytochrome c-1 /DB_XREF=gi:4503184 /UG=Hs.289271 cytochrome c-1 /FL=gb:BC001006.1 gb:NM_001916.1" NM_001916 cytochrome c-1 CYC1 1537 NM_001916 0022904 // respiratory electron transport chain // traceable author statement /// 0033762 // response to glucagon // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation "0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0045155 // electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation" 201067_at BF215487 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF215487 /FEA=EST /DB_XREF=gi:11109176 /DB_XREF=est:601881048F1 /CLONE=IMAGE:4093691 /UG=Hs.61153 proteasome (prosome, macropain) 26S subunit, ATPase, 2 /FL=gb:BC002589.1 gb:D11094.1 gb:NM_002803.1" BF215487 "proteasome (prosome, macropain) 26S subunit, ATPase, 2" PSMC2 5701 NM_001204453 /// NM_002803 /// XM_005250505 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201068_s_at NM_002803 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002803.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), mRNA. /FEA=mRNA /GEN=PSMC2 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 2 /DB_XREF=gi:4506208 /UG=Hs.61153 proteasome (prosome, macropain) 26S subunit, ATPase, 2 /FL=gb:BC002589.1 gb:D11094.1 gb:NM_002803.1" NM_002803 "proteasome (prosome, macropain) 26S subunit, ATPase, 2" PSMC2 5701 NM_001204453 /// NM_002803 /// XM_005250505 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // inferred from direct assay /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201069_at NM_004530 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004530.1 /DEF=Homo sapiens matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase) (MMP2), mRNA. /FEA=mRNA /GEN=MMP2 /PROD=matrix metalloproteinase 2 preproprotein /DB_XREF=gi:11342665 /UG=Hs.111301 matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase) /FL=gb:NM_004530.1 gb:BC002576.1" NM_004530 "matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)" MMP2 4313 NM_001127891 /// NM_004530 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001955 // blood vessel maturation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201070_x_at AI739389 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI739389 /FEA=EST /DB_XREF=gi:5101370 /DB_XREF=est:wi29f09.x1 /CLONE=IMAGE:2391689 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD /FL=gb:AF054284.1 gb:NM_012433.1" AI739389 "splicing factor 3b, subunit 1, 155kDa" SF3B1 23451 NM_001005526 /// NM_012433 /// XM_005246428 /// XR_241300 /// XR_241301 /// XR_241302 "0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201071_x_at NM_012433 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012433.1 /DEF=Homo sapiens splicing factor 3b, subunit 1, 155kD (SF3B1), mRNA. /FEA=mRNA /GEN=SF3B1 /PROD=splicing factor 3b, subunit 1, 155kD /DB_XREF=gi:6912653 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD /FL=gb:AF054284.1 gb:NM_012433.1" NM_012433 "splicing factor 3b, subunit 1, 155kDa" SF3B1 23451 NM_001005526 /// NM_012433 /// XM_005246428 /// XR_241300 /// XR_241301 /// XR_241302 "0000375 // RNA splicing, via transesterification reactions // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201072_s_at AW152160 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW152160 /FEA=EST /DB_XREF=gi:6200058 /DB_XREF=est:xf75e01.x1 /CLONE=IMAGE:2623896 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1" AW152160 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" SMARCC1 6599 NM_003074 "0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201073_s_at AL040633 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL040633 /FEA=EST /DB_XREF=gi:5409580 /DB_XREF=est:DKFZp434M2414_s1 /CLONE=DKFZp434M2414 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1" AL040633 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" SMARCC1 6599 NM_003074 "0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201074_at AA593983 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA593983 /FEA=EST /DB_XREF=gi:2409333 /DB_XREF=est:nn16d01.s1 /CLONE=IMAGE:1084033 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1" AA593983 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" SMARCC1 6599 NM_003074 "0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201075_s_at NM_003074 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003074.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (SMARCC1), mRNA. /FEA=mRNA /GEN=SMARCC1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily c, member 1 /DB_XREF=gi:4507078 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1" NM_003074 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" SMARCC1 6599 NM_003074 "0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity /// 0071778 // WINAC complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201076_at NM_005008 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005008.1 /DEF=Homo sapiens non-histone chromosome protein 2 (S. cerevisiae)-like 1 (NHP2L1), mRNA. /FEA=mRNA /GEN=NHP2L1 /PROD=non-histone chromosome protein 2 (S.cerevisiae)-like 1 /DB_XREF=gi:4826859 /UG=Hs.182255 non-histone chromosome protein 2 (S. cerevisiae)-like 1 /FL=gb:BC005358.1 gb:D50420.1 gb:AF091076.1 gb:NM_005008.1 gb:AF155235.1" NM_005008 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) NHP2L1 4809 NM_001003796 /// NM_005008 /// XM_005261620 /// XM_006724258 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031428 // box C/D snoRNP complex // non-traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030515 // snoRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201077_s_at AF155235 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF155235.1 /DEF=Homo sapiens 15.5 kD RNA binding protein mRNA, complete cds. /FEA=mRNA /PROD=15.5 kD RNA binding protein /DB_XREF=gi:6318598 /UG=Hs.182255 non-histone chromosome protein 2 (S. cerevisiae)-like 1 /FL=gb:BC005358.1 gb:D50420.1 gb:AF091076.1 gb:NM_005008.1 gb:AF155235.1" AF155235 annexin A2 /// NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) ANXA2 /// NHP2L1 302 /// 4809 NM_001002857 /// NM_001002858 /// NM_001003796 /// NM_001136015 /// NM_004039 /// NM_005008 /// XM_005261620 /// XM_006724258 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation" 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031428 // box C/D snoRNP complex // non-traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003723 // RNA binding // traceable author statement /// 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0030515 // snoRNA binding // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction" 201078_at NM_004800 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004800.1 /DEF=Homo sapiens transmembrane 9 superfamily member 2 (TM9SF2), mRNA. /FEA=mRNA /GEN=TM9SF2 /PROD=transmembrane 9 superfamily member 2 /DB_XREF=gi:4758873 /UG=Hs.28757 transmembrane 9 superfamily member 2 /FL=gb:U81006.1 gb:NM_004800.1" NM_004800 transmembrane 9 superfamily member 2 TM9SF2 9375 NM_004800 0006810 // transport // traceable author statement 0005768 // endosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201079_at NM_004710 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004710.1 /DEF=Homo sapiens synaptogyrin 2 (SYNGR2), mRNA. /FEA=mRNA /GEN=SYNGR2 /PROD=synaptogyrin 2 /DB_XREF=gi:4759201 /UG=Hs.5097 synaptogyrin 2 /FL=gb:BC000407.1 gb:NM_004710.1" NM_004710 synaptogyrin 2 SYNGR2 9144 NM_004710 /// XM_005257792 /// XM_005257793 0006605 // protein targeting // inferred from electronic annotation 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201080_at BF338509 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF338509 /FEA=EST /DB_XREF=gi:11284912 /DB_XREF=est:602034176F2 /CLONE=IMAGE:4182187 /UG=Hs.6335 phosphatidylinositol-4-phosphate 5-kinase, type II, beta /FL=gb:U85245.1 gb:NM_003559.1" BF338509 "phosphatidylinositol-5-phosphate 4-kinase, type II, beta" PIP4K2B 8396 NM_003559 /// NM_138687 /// XM_006722130 /// XM_006722131 /// XM_006722132 /// XM_006725363 /// XM_006725364 /// XM_006725365 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201081_s_at NM_003559 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003559.1 /DEF=Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type II, beta (PIP5K2B), mRNA. /FEA=mRNA /GEN=PIP5K2B /PROD=phosphatidylinositol-4-phosphate 5-kinase, typeII, beta /DB_XREF=gi:4505818 /UG=Hs.6335 phosphatidylinositol-4-phosphate 5-kinase, type II, beta /FL=gb:U85245.1 gb:NM_003559.1" NM_003559 "phosphatidylinositol-5-phosphate 4-kinase, type II, beta" PIP4K2B 8396 NM_003559 /// NM_138687 /// XM_006722130 /// XM_006722131 /// XM_006722132 /// XM_006725363 /// XM_006725364 /// XM_006725365 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from direct assay /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201082_s_at NM_004082 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004082.2 /DEF=Homo sapiens dynactin 1 (p150, Glued (Drosophila) homolog) (DCTN1), transcript variant 1, mRNA. /FEA=mRNA /GEN=DCTN1 /PROD=dynactin 1, isoform 1 /DB_XREF=gi:13259509 /UG=Hs.74617 dynactin 1 (p150, Glued (Drosophila) homolog) /FL=gb:NM_023019.1 gb:NM_004082.2" NM_004082 "dynactin 1 /// solute carrier family 4 (sodium bicarbonate cotransporter), member 5" DCTN1 /// SLC4A5 1639 /// 57835 NM_001135040 /// NM_001135041 /// NM_001190836 /// NM_001190837 /// NM_004082 /// NM_021196 /// NM_023019 /// NM_033323 /// NM_133478 /// NM_133479 /// NR_033935 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010970 // microtubule-based transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000776 // kinetochore // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0045502 // dynein binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 201083_s_at AA740754 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA740754 /FEA=EST /DB_XREF=gi:2779346 /DB_XREF=est:nz03b05.s1 /CLONE=IMAGE:1286673 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 AA740754 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 /// XM_005267236 /// XM_005267237 /// XM_005267238 /// XM_005267239 /// XR_245558 /// XR_245559 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 2000144 // positive regulation of DNA-templated transcription, initiation // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201084_s_at NM_014739 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014739.1 /DEF=Homo sapiens KIAA0164 gene product (KIAA0164), mRNA. /FEA=mRNA /GEN=KIAA0164 /PROD=KIAA0164 gene product /DB_XREF=gi:7661957 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1" NM_014739 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 /// XM_005267236 /// XM_005267237 /// XM_005267238 /// XM_005267239 /// XR_245558 /// XR_245559 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 2000144 // positive regulation of DNA-templated transcription, initiation // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201085_s_at AA664291 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA664291 /FEA=EST /DB_XREF=gi:2618282 /DB_XREF=est:ac08d09.s1 /CLONE=IMAGE:855857 /UG=Hs.92909 SON DNA binding protein /FL=gb:NM_003103.1 AA664291 SON DNA binding protein SON 6651 NM_001291411 /// NM_001291412 /// NM_003103 /// NM_032195 /// NM_138925 /// NM_138927 /// NR_103796 /// NR_103797 /// NR_103798 /// XM_006724043 /// XM_006724044 /// XM_006724045 /// XR_430355 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201086_x_at NM_003103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003103.1 /DEF=Homo sapiens SON DNA binding protein (SON), mRNA. /FEA=mRNA /GEN=SON /PROD=SON DNA binding protein /DB_XREF=gi:4507152 /UG=Hs.92909 SON DNA binding protein /FL=gb:NM_003103.1" NM_003103 SON DNA binding protein SON 6651 NM_001291411 /// NM_001291412 /// NM_003103 /// NM_032195 /// NM_138925 /// NM_138927 /// NR_103796 /// NR_103797 /// NR_103798 /// XM_006724043 /// XM_006724044 /// XM_006724045 /// XR_430355 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201087_at NM_002859 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002859.1 /DEF=Homo sapiens paxillin (PXN), mRNA. /FEA=mRNA /GEN=PXN /PROD=paxillin /DB_XREF=gi:4506344 /UG=Hs.102497 paxillin /FL=gb:NM_002859.1 gb:U14588.1" NM_002859 paxillin PXN 5829 NM_001080855 /// NM_001243756 /// NM_002859 /// NM_025157 /// XM_005253910 /// XM_005253912 /// XM_005253913 /// XM_005253914 /// XM_005253915 /// XM_005253916 /// XM_005253917 /// XM_006719531 /// XM_006719532 /// XM_006719533 /// XM_006719534 /// XM_006719535 /// XM_006719536 /// XM_006719537 /// XM_006719538 /// XM_006719539 /// XR_243019 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051435 // BH4 domain binding // inferred from electronic annotation 201088_at NM_002266 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002266.1 /DEF=Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), mRNA. /FEA=mRNA /GEN=KPNA2 /PROD=karyopherin alpha 2 /DB_XREF=gi:4504896 /UG=Hs.159557 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) /FL=gb:NM_002266.1 gb:U09559.1 gb:U28386.1" NM_002266 "karyopherin alpha 2 (RAG cohort 1, importin alpha 1)" KPNA2 3838 NM_002266 0000018 // regulation of DNA recombination // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201089_at NM_001693 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001693.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 2 (ATP6B2), mRNA. /FEA=mRNA /GEN=ATP6B2 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), beta polypeptide, 5658kD, isoform 2 /DB_XREF=gi:4502310 /UG=Hs.1697 ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 2 /FL=gb:BC003100.1 gb:NM_001693.1 gb:L35249.1" NM_001693 "ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2" ATP6V1B2 526 NM_001693 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005902 // microvillus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0005524 // ATP binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 201090_x_at NM_006082 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006082.1 /DEF=Homo sapiens tubulin, alpha, ubiquitous (K-ALPHA-1), mRNA. /FEA=mRNA /GEN=K-ALPHA-1 /PROD=tubulin, alpha, ubiquitous /DB_XREF=gi:5174476 /UG=Hs.278242 tubulin, alpha, ubiquitous /FL=gb:BC000696.1 gb:BC001128.1 gb:BC001209.1 gb:K00558.1 gb:AF081484.1 gb:NM_006082.1" NM_006082 "tubulin, alpha 1b" TUBA1B 10376 NM_006082 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 201091_s_at BE748755 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE748755 /FEA=EST /DB_XREF=gi:10162747 /DB_XREF=est:601571933T1 /CLONE=IMAGE:3838737 /UG=Hs.278554 heterochromatin-like protein 1 /FL=gb:AF136630.1 gb:NM_016587.1 BE748755 chromobox homolog 3 CBX3 11335 NM_007276 /// NM_016587 /// XM_005249611 /// XM_005249612 "0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation" "0000779 // condensed chromosome, centromeric region // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005637 // nuclear inner membrane // non-traceable author statement /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0031618 // nuclear centromeric heterochromatin // inferred from sequence or structural similarity" 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 1990226 // histone methyltransferase binding // inferred from physical interaction 201092_at NM_002893 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002893.2 /DEF=Homo sapiens retinoblastoma-binding protein 7 (RBBP7), mRNA. /FEA=mRNA /GEN=RBBP7 /PROD=retinoblastoma-binding protein 7 /DB_XREF=gi:13259504 /UG=Hs.31314 retinoblastoma-binding protein 7 /FL=gb:U35143.1 gb:NM_002893.2" NM_002893 retinoblastoma binding protein 7 RBBP7 5931 NM_001198719 /// NM_002893 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0070370 // cellular heat acclimation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016581 // NuRD complex // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201093_x_at NM_004168 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004168.1 /DEF=Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHA /PROD=succinate dehydrogenase complex, subunit A,flavoprotein precursor /DB_XREF=gi:4759079 /UG=Hs.469 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) /FL=gb:BC001380.1 gb:L21936.1 gb:NM_004168.1 gb:D30648.1" NM_004168 "succinate dehydrogenase complex, subunit A, flavoprotein (Fp)" SDHA 6389 NM_001294332 /// NM_004168 /// XM_005248329 /// XM_005248331 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006105 // succinate metabolic process // inferred from direct assay /// 0007399 // nervous system development // inferred from mutant phenotype /// 0022900 // electron transport chain // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0005749 // mitochondrial respiratory chain complex II // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0000104 // succinate dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008177 // succinate dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 201094_at NM_001032 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001032.1 /DEF=Homo sapiens ribosomal protein S29 (RPS29), mRNA. /FEA=mRNA /GEN=RPS29 /PROD=ribosomal protein S29 /DB_XREF=gi:4506716 /UG=Hs.539 ribosomal protein S29 /FL=gb:L31610.1 gb:NM_001032.1 gb:U14973.1" NM_001032 ribosomal protein S29 RPS29 6235 NM_001030001 /// NM_001032 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201095_at NM_004394 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004394.1 /DEF=Homo sapiens death-associated protein (DAP), mRNA. /FEA=mRNA /GEN=DAP /PROD=death-associated protein /DB_XREF=gi:4758119 /UG=Hs.75189 death-associated protein /FL=gb:BC002726.1 gb:NM_004394.1" NM_004394 death-associated protein DAP 1611 NM_001291963 /// NM_004394 "0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0010507 // negative regulation of autophagy // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0034198 // cellular response to amino acid starvation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype" 0070513 // death domain binding // inferred from physical interaction 201096_s_at AL537042 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL537042 /FEA=EST /DB_XREF=gi:12800535 /DB_XREF=est:AL537042 /CLONE=CS0DF017YF17 (5 prime) /UG=Hs.75290 ADP-ribosylation factor 4 /FL=gb:BC003364.1 gb:M36341.1 gb:NM_001660.2 AL537042 ADP-ribosylation factor 4 ARF4 378 NM_001660 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201097_s_at NM_001660 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001660.2 /DEF=Homo sapiens ADP-ribosylation factor 4 (ARF4), mRNA. /FEA=mRNA /GEN=ARF4 /PROD=ADP-ribosylation factor 4 /DB_XREF=gi:6995998 /UG=Hs.75290 ADP-ribosylation factor 4 /FL=gb:BC003364.1 gb:M36341.1 gb:NM_001660.2" NM_001660 ADP-ribosylation factor 4 ARF4 378 NM_001660 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201098_at NM_004766 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004766.1 /DEF=Homo sapiens coatomer protein complex, subunit beta 2 (beta prime) (COPB2), mRNA. /FEA=mRNA /GEN=COPB2 /PROD=coatomer protein complex, subunit beta 2 (betaprime) /DB_XREF=gi:4758031 /UG=Hs.75724 coatomer protein complex, subunit beta 2 (beta prime) /FL=gb:BC000326.1 gb:NM_004766.1" NM_004766 "coatomer protein complex, subunit beta 2 (beta prime)" COPB2 9276 NM_004766 /// NR_023350 "0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201099_at AA824386 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA824386 /FEA=EST /DB_XREF=gi:2896270 /DB_XREF=est:aj29c05.s1 /CLONE=1391720 /UG=Hs.77578 ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) /FL=gb:NM_004652.2" AA824386 "ubiquitin specific peptidase 9, X-linked" USP9X 8239 NM_001039590 /// NM_001039591 /// NM_004652 /// NM_021906 /// XM_005272675 /// XM_005272676 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001764 // neuron migration // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0048675 // axon extension // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction 201100_s_at NM_004652 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004652.2 /DEF=Homo sapiens ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) (USP9X), transcript variant 1, mRNA. /FEA=mRNA /GEN=USP9X /PROD=Drosophila fat facets related, X-linked, isoform1 /DB_XREF=gi:11641424 /UG=Hs.77578 ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) /FL=gb:NM_004652.2" NM_004652 "ubiquitin specific peptidase 9, X-linked" USP9X 8239 NM_001039590 /// NM_001039591 /// NM_004652 /// NM_021906 /// XM_005272675 /// XM_005272676 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001764 // neuron migration // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007292 // female gamete generation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016579 // protein deubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0048675 // axon extension // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction 201101_s_at BE963370 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE963370 /FEA=EST /DB_XREF=gi:11766788 /DB_XREF=est:601657132R1 /CLONE=IMAGE:3866335 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 BE963370 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 /// XM_005267236 /// XM_005267237 /// XM_005267238 /// XM_005267239 /// XR_245558 /// XR_245559 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 2000144 // positive regulation of DNA-templated transcription, initiation // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201102_s_at NM_002626 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002626.1 /DEF=Homo sapiens phosphofructokinase, liver (PFKL), mRNA. /FEA=mRNA /GEN=PFKL /PROD=phosphofructokinase, liver /DB_XREF=gi:4505746 /UG=Hs.155455 phosphofructokinase, liver /FL=gb:BC004920.1 gb:X15573.1 gb:NM_002626.1" NM_002626 "phosphofructokinase, liver" PFKL 5211 NM_001002021 /// NM_002626 /// NR_024108 /// XM_005261135 /// XM_005261136 /// XM_005261137 /// XM_006724011 /// XM_006724012 "0005975 // carbohydrate metabolic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from direct assay /// 0006002 // fructose 6-phosphate metabolic process // inferred from mutant phenotype /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005945 // 6-phosphofructokinase complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from direct assay /// 0003872 // 6-phosphofructokinase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation /// 0070061 // fructose binding // inferred from direct assay /// 0070095 // fructose-6-phosphate binding // inferred from direct assay 201103_x_at BE299495 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE299495 /FEA=EST /DB_XREF=gi:9183243 /DB_XREF=est:600944774T1 /CLONE=IMAGE:2960610 /UG=Hs.218329 hypothetical protein /FL=gb:NM_015383.1 BE299495 "neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 12 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 9" NBPF10 /// NBPF11 /// NBPF12 /// NBPF14 /// NBPF15 /// NBPF20 /// NBPF8 /// NBPF9 25832 /// 149013 /// 200030 /// 284565 /// 400818 /// 728841 /// 100132406 /// 100288142 NM_001037501 /// NM_001037675 /// NM_001039703 /// NM_001101663 /// NM_001102663 /// NM_001170755 /// NM_001277444 /// NM_001278141 /// NM_001278267 /// NM_015383 /// NM_173638 /// NM_183372 /// NR_046188 /// NR_102404 /// NR_102405 /// NR_110864 /// XM_005245096 /// XM_005245097 /// XM_005277342 /// XM_005277343 /// XM_005277344 /// XM_005277345 /// XM_005277346 /// XM_005277347 /// XM_006710872 /// XM_006711103 /// XM_006711104 /// XM_006711179 /// XM_006711180 /// XM_006711181 /// XM_006711182 /// XM_006711197 /// XM_006711265 /// XM_006711317 /// XR_254328 /// XR_426769 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 201104_x_at NM_015383 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015383.1 /DEF=Homo sapiens hypothetical protein (DJ328E19.C1.1), mRNA. /FEA=mRNA /GEN=DJ328E19.C1.1 /PROD=hypothetical protein /DB_XREF=gi:7657016 /UG=Hs.218329 hypothetical protein /FL=gb:NM_015383.1" NM_015383 "neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 19 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 25, pseudogene /// neuroblastoma breakpoint family, member 26 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 9" NBPF10 /// NBPF11 /// NBPF14 /// NBPF15 /// NBPF19 /// NBPF20 /// NBPF25P /// NBPF26 /// NBPF8 /// NBPF9 25832 /// 200030 /// 284565 /// 400818 /// 728841 /// 100132406 /// 100288142 /// 101060226 /// 101060684 /// 101929780 NM_001037501 /// NM_001037675 /// NM_001039703 /// NM_001101663 /// NM_001102663 /// NM_001170755 /// NM_001277444 /// NM_001278267 /// NM_015383 /// NM_173638 /// NM_183372 /// NR_046188 /// NR_102404 /// NR_102405 /// NR_104217 /// NR_110864 /// XM_003960069 /// XM_003960230 /// XM_005245096 /// XM_005245097 /// XM_005276139 /// XM_005276140 /// XM_005276167 /// XM_005276168 /// XM_005276169 /// XM_005276170 /// XM_005276171 /// XM_005276172 /// XM_005276173 /// XM_005276174 /// XM_005276175 /// XM_005276176 /// XM_005276177 /// XM_005276178 /// XM_005276179 /// XM_005276180 /// XM_005276181 /// XM_005276182 /// XM_005276183 /// XM_005276184 /// XM_005276185 /// XM_005276186 /// XM_005276187 /// XM_005277469 /// XM_005277470 /// XM_005277471 /// XM_005277472 /// XM_005277473 /// XM_005277474 /// XM_005277475 /// XM_005277476 /// XM_005277477 /// XM_005277478 /// XM_005277479 /// XM_005277480 /// XM_005277481 /// XM_005277482 /// XM_005277483 /// XM_005277484 /// XM_005277485 /// XM_005277486 /// XM_005277487 /// XM_005277488 /// XM_005277503 /// XM_005277504 /// XM_005277505 /// XM_006710872 /// XM_006711091 /// XM_006711092 /// XM_006711093 /// XM_006711094 /// XM_006711095 /// XM_006711096 /// XM_006711103 /// XM_006711104 /// XM_006711197 /// XM_006711265 /// XM_006711317 /// XM_006711707 /// XM_006711708 /// XM_006711709 /// XM_006711710 /// XM_006711711 /// XM_006711712 /// XM_006726340 /// XM_006726341 /// XM_006726342 /// XM_006726343 /// XM_006726344 /// XM_006726345 /// XM_006726360 /// XM_006726361 /// XM_006726362 /// XM_006726363 /// XM_006726364 /// XM_006726365 /// XR_426769 0005737 // cytoplasm // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 201105_at NM_002305 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002305.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 1 (galectin 1) (LGALS1), mRNA. /FEA=mRNA /GEN=LGALS1 /PROD=beta-galactosidase binding lectin precursor /DB_XREF=gi:6006015 /UG=Hs.227751 lectin, galactoside-binding, soluble, 1 (galectin 1) /FL=gb:BC001693.1 gb:J04456.1 gb:NM_002305.2" NM_002305 "lectin, galactoside-binding, soluble, 1" LGALS1 3956 NM_002305 0002317 // plasma cell differentiation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034120 // positive regulation of erythrocyte aggregation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016936 // galactoside binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030395 // lactose binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201106_at NM_002085 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002085.1 /DEF=Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), mRNA. /FEA=mRNA /GEN=GPX4 /PROD=glutathione peroxidase 4 /DB_XREF=gi:4504106 /UG=Hs.2706 glutathione peroxidase 4 (phospholipid hydroperoxidase) /FL=gb:NM_002085.1" NM_002085 glutathione peroxidase 4 GPX4 2879 NM_001039847 /// NM_001039848 /// NM_002085 0006325 // chromatin organization // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043295 // glutathione binding // inferred from electronic annotation /// 0047066 // phospholipid-hydroperoxide glutathione peroxidase activity // inferred from electronic annotation 201107_s_at AI812030 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI812030 /FEA=EST /DB_XREF=gi:5398596 /DB_XREF=est:tw46c12.x1 /CLONE=IMAGE:2262742 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 AI812030 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201108_s_at BF055462 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF055462 /FEA=EST /DB_XREF=gi:10809358 /DB_XREF=est:7j80e06.x1 /CLONE=IMAGE:3392770 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 BF055462 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201109_s_at AV726673 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV726673 /FEA=EST /DB_XREF=gi:10836094 /DB_XREF=est:AV726673 /CLONE=HTCBGC12 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 AV726673 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201110_s_at NM_003246 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003246.1 /DEF=Homo sapiens thrombospondin 1 (THBS1), mRNA. /FEA=mRNA /GEN=THBS1 /PROD=thrombospondin 1 /DB_XREF=gi:4507484 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1" NM_003246 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // non-traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from sequence or structural similarity /// 0033574 // response to testosterone // inferred from electronic annotation /// 0034605 // cellular response to heat // non-traceable author statement /// 0034976 // response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from expression pattern /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0048266 // behavioral response to pain // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion assembly // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071636 // positive regulation of transforming growth factor beta production // inferred from electronic annotation /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000353 // positive regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001786 // phosphatidylserine binding // inferred from direct assay /// 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0050840 // extracellular matrix binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from direct assay /// 0070052 // collagen V binding // inferred from direct assay 201111_at AF053641 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF053641.1 /DEF=Homo sapiens brain cellular apoptosis susceptibility protein (CSE1) mRNA, complete cds. /FEA=mRNA /GEN=CSE1 /PROD=cellular apoptosis susceptibility protein /DB_XREF=gi:3560556 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:U33286.1 gb:AF053641.1 gb:NM_001316.1" AF053641 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001256135 /// NM_001316 /// NM_177436 /// NR_045796 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 201112_s_at NM_001316 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001316.1 /DEF=Homo sapiens chromosome segregation 1 (yeast homolog)-like (CSE1L), mRNA. /FEA=mRNA /GEN=CSE1L /PROD=chromosome segregation 1 (yeast homolog)-like /DB_XREF=gi:4503072 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:U33286.1 gb:AF053641.1 gb:NM_001316.1" NM_001316 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001256135 /// NM_001316 /// NM_177436 /// NR_045796 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation 201113_at NM_003321 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003321.1 /DEF=Homo sapiens Tu translation elongation factor, mitochondrial (TUFM), mRNA. /FEA=mRNA /GEN=TUFM /PROD=Tu translation elongation factor, mitochondrial /DB_XREF=gi:4507732 /UG=Hs.12084 Tu translation elongation factor, mitochondrial /FL=gb:BC001633.1 gb:NM_003321.1 gb:L38995.1" NM_003321 "Tu translation elongation factor, mitochondrial" TUFM 7284 NM_003321 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from direct assay /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201114_x_at NM_002792 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002792.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7), mRNA. /FEA=mRNA /GEN=PSMA7 /PROD=proteasome (prosome, macropain) subunit, alphatype, 7 /DB_XREF=gi:4506188 /UG=Hs.233952 proteasome (prosome, macropain) subunit, alpha type, 7 /FL=gb:BC004427.1 gb:AF022815.1 gb:AF054185.1 gb:NM_002792.1" NM_002792 "proteasome (prosome, macropain) subunit, alpha type, 7" PSMA7 5688 NM_002792 /// NM_152255 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" "0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201115_at NM_006230 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006230.1 /DEF=Homo sapiens polymerase (DNA directed), delta 2, regulatory subunit (50kD) (POLD2), mRNA. /FEA=mRNA /GEN=POLD2 /PROD=polymerase (DNA directed), delta 2, regulatorysubunit (50kD) /DB_XREF=gi:5453923 /UG=Hs.74598 polymerase (DNA directed), delta 2, regulatory subunit (50kD) /FL=gb:U21090.1 gb:BC000459.1 gb:NM_006230.1" NM_006230 "polymerase (DNA directed), delta 2, accessory subunit" POLD2 5425 NM_001127218 /// NM_001256879 /// NM_006230 /// XM_006715745 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0043625 // delta DNA polymerase complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 201116_s_at AI922855 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI922855 /FEA=EST /DB_XREF=gi:5658819 /DB_XREF=est:wo14h05.x1 /CLONE=IMAGE:2455353 /UG=Hs.75360 carboxypeptidase E /FL=gb:NM_001873.1 AI922855 carboxypeptidase E CPE 1363 NM_001873 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030070 // insulin processing // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072657 // protein localization to membrane // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 201117_s_at NM_001873 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001873.1 /DEF=Homo sapiens carboxypeptidase E (CPE), mRNA. /FEA=mRNA /GEN=CPE /PROD=carboxypeptidase E precursor /DB_XREF=gi:4503008 /UG=Hs.75360 carboxypeptidase E /FL=gb:NM_001873.1" NM_001873 carboxypeptidase E CPE 1363 NM_001873 0003214 // cardiac left ventricle morphogenesis // inferred from mutant phenotype /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030070 // insulin processing // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0072657 // protein localization to membrane // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 201118_at NM_002631 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002631.1 /DEF=Homo sapiens phosphogluconate dehydrogenase (PGD), mRNA. /FEA=mRNA /GEN=PGD /PROD=phosphogluconate dehydrogenase /DB_XREF=gi:4505758 /UG=Hs.75888 phosphogluconate dehydrogenase /FL=gb:BC000368.1 gb:NM_002631.1 gb:U30255.1" NM_002631 phosphogluconate dehydrogenase PGD 5226 NM_002631 "0005975 // carbohydrate metabolic process // traceable author statement /// 0006098 // pentose-phosphate shunt // inferred from sequence or structural similarity /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from direct assay /// 0019322 // pentose biosynthetic process // inferred from electronic annotation /// 0019521 // D-gluconate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // not recorded /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation" 201119_s_at NM_004074 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004074.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIII (COX8), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX8 /PROD=cytochrome c oxidase subunit VIII /DB_XREF=gi:4758043 /UG=Hs.81097 cytochrome c oxidase subunit VIII /FL=gb:NM_004074.1" NM_004074 cytochrome c oxidase subunit VIIIA (ubiquitous) COX8A 1351 NM_004074 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201120_s_at AL547946 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL547946 /FEA=EST /DB_XREF=gi:12882489 /DB_XREF=est:AL547946 /CLONE=CS0DI035YB22 (5 prime) /UG=Hs.90061 progesterone binding protein /FL=gb:NM_006667.2 AL547946 progesterone receptor membrane component 1 PGRMC1 10857 NM_001282621 /// NM_006667 0007411 // axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 201121_s_at NM_006667 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006667.2 /DEF=Homo sapiens progesterone binding protein (HPR6.6), mRNA. /FEA=mRNA /GEN=HPR6.6 /PROD=progesterone binding protein /DB_XREF=gi:6857798 /UG=Hs.90061 progesterone binding protein /FL=gb:NM_006667.2" NM_006667 progesterone receptor membrane component 1 PGRMC1 10857 NM_001282621 /// NM_006667 0007411 // axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 201122_x_at BC000751 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000751.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 5A, clone MGC:2453, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 5A /DB_XREF=gi:12653914 /UG=Hs.119140 eukaryotic translation initiation factor 5A /FL=gb:BC000751.1 gb:BC001832.1 gb:M23419.1 gb:NM_001970.1" BC000751 eukaryotic translation initiation factor 5A EIF5A 1984 NM_001143760 /// NM_001143761 /// NM_001143762 /// NM_001970 /// XM_005256509 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0006452 // translational frameshifting // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045901 // positive regulation of translational elongation // inferred from sequence or structural similarity /// 0045905 // positive regulation of translational termination // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005642 // annulate lamellae // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003746 // translation elongation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0043022 // ribosome binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201123_s_at NM_001970 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001970.1 /DEF=Homo sapiens eukaryotic translation initiation factor 5A (EIF5A), mRNA. /FEA=mRNA /GEN=EIF5A /PROD=eukaryotic translation initiation factor 5A /DB_XREF=gi:4503544 /UG=Hs.119140 eukaryotic translation initiation factor 5A /FL=gb:BC000751.1 gb:BC001832.1 gb:M23419.1 gb:NM_001970.1" NM_001970 eukaryotic translation initiation factor 5A EIF5A 1984 NM_001143760 /// NM_001143761 /// NM_001143762 /// NM_001970 /// XM_005256509 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0006452 // translational frameshifting // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045901 // positive regulation of translational elongation // inferred from sequence or structural similarity /// 0045905 // positive regulation of translational termination // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005642 // annulate lamellae // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003746 // translation elongation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0043022 // ribosome binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201124_at AL048423 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL048423 /FEA=EST /DB_XREF=gi:5936493 /DB_XREF=est:DKFZp586H2324_s1 /CLONE=DKFZp586H2324 /UG=Hs.149846 integrin, beta 5 /FL=gb:M35011.1 gb:J05633.1 gb:NM_002213.1" AL048423 "integrin, beta 5" ITGB5 3693 NM_002213 /// XM_005247436 /// XM_006713630 "0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement" 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201125_s_at NM_002213 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002213.1 /DEF=Homo sapiens integrin, beta 5 (ITGB5), mRNA. /FEA=mRNA /GEN=ITGB5 /PROD=integrin, beta 5 /DB_XREF=gi:4504772 /UG=Hs.149846 integrin, beta 5 /FL=gb:M35011.1 gb:J05633.1 gb:NM_002213.1" NM_002213 "integrin, beta 5" ITGB5 3693 NM_002213 /// XM_005247436 /// XM_006713630 "0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement" 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201126_s_at NM_002406 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002406.2 /DEF=Homo sapiens mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1), mRNA. /FEA=mRNA /GEN=MGAT1 /PROD=mannosyl (alpha-1,3-)-glycoproteinbeta-1,2-N-acetylglucosaminyltransferase /DB_XREF=gi:6031182 /UG=Hs.151513 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase /FL=gb:M55621.1 gb:NM_002406.2" NM_002406 "mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase" MGAT1 4245 NM_001114617 /// NM_001114618 /// NM_001114619 /// NM_001114620 /// NM_002406 /// XM_005265915 /// XM_005265916 /// XM_006714866 /// XM_006714867 0001701 // in utero embryonic development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006049 // UDP-N-acetylglucosamine catabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003827 // alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201127_s_at AI971281 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI971281 /FEA=EST /DB_XREF=gi:5768107 /DB_XREF=est:wr27d10.x1 /CLONE=IMAGE:2488915 /UG=Hs.174140 ATP citrate lyase /FL=gb:NM_001096.1 AI971281 ATP citrate lyase ACLY 47 NM_001096 /// NM_198830 /// XM_005257393 /// XM_005257394 /// XM_005257395 0006101 // citrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0015936 // coenzyme A metabolic process // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009346 // citrate lyase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // traceable author statement /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation" 201128_s_at NM_001096 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001096.1 /DEF=Homo sapiens ATP citrate lyase (ACLY), mRNA. /FEA=mRNA /GEN=ACLY /PROD=ATP citrate lyase /DB_XREF=gi:4501864 /UG=Hs.174140 ATP citrate lyase /FL=gb:NM_001096.1" NM_001096 ATP citrate lyase ACLY 47 NM_001096 /// NM_198830 /// XM_005257393 /// XM_005257394 /// XM_005257395 0006101 // citrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0015936 // coenzyme A metabolic process // traceable author statement /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009346 // citrate lyase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // traceable author statement /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation" 201129_at NM_006276 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006276.2 /DEF=Homo sapiens splicing factor, arginineserine-rich 7 (35kD) (SFRS7), mRNA. /FEA=mRNA /GEN=SFRS7 /PROD=splicing factor, arginineserine-rich 7 (35kD) /DB_XREF=gi:6857827 /UG=Hs.184167 splicing factor, arginineserine-rich 7 (35kD) /FL=gb:BC000997.2 gb:L22253.1 gb:NM_006276.2" NM_006276 serine/arginine-rich splicing factor 7 SRSF7 6432 NM_001031684 /// NM_001195446 /// NM_006276 /// XM_005264484 /// XM_005264485 /// XM_005264486 /// XR_426994 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201130_s_at L08599 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L08599.1 /DEF=Human uvomorulin (E-cadherin) (UVO) mRNA, complete cds. /FEA=mRNA /GEN=UVO /PROD=uvomorulin /DB_XREF=gi:340184 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) /FL=gb:L08599.1 gb:NM_004360.1" L08599 "cadherin 1, type 1, E-cadherin (epithelial)" CDH1 999 NM_004360 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from direct assay /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000008 // regulation of protein localization to cell surface // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016342 // catenin complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0032794 // GTPase activating protein binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // non-traceable author statement 201131_s_at NM_004360 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004360.1 /DEF=Homo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1), mRNA. /FEA=mRNA /GEN=CDH1 /PROD=cadherin 1, type 1, E-cadherin (epithelial) /DB_XREF=gi:4757959 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) /FL=gb:L08599.1 gb:NM_004360.1" NM_004360 "cadherin 1, type 1, E-cadherin (epithelial)" CDH1 999 NM_004360 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0003382 // epithelial cell morphogenesis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0022408 // negative regulation of cell-cell adhesion // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0060576 // intestinal epithelial cell development // inferred from electronic annotation /// 0060662 // salivary gland cavitation // inferred from electronic annotation /// 0060693 // regulation of branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from direct assay /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 2000008 // regulation of protein localization to cell surface // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from mutant phenotype /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016342 // catenin complex // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0030424 // axon // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from direct assay /// 0043679 // axon terminus // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030506 // ankyrin binding // inferred from physical interaction /// 0032794 // GTPase activating protein binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // non-traceable author statement 201132_at NM_019597 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019597.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein H2 (H) (HNRPH2), mRNA. /FEA=mRNA /GEN=HNRPH2 /PROD=heterogeneous nuclear ribonucleoprotein H2 (H) /DB_XREF=gi:9624997 /UG=Hs.278857 heterogeneous nuclear ribonucleoprotein H2 (H) /FL=gb:NM_019597.1" NM_019597 heterogeneous nuclear ribonucleoprotein H2 (H') /// RPL36A-HNRNPH2 readthrough HNRNPH2 /// RPL36A-HNRNPH2 3188 /// 100529097 NM_001032393 /// NM_001199973 /// NM_001199974 /// NM_019597 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201133_s_at AA142966 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA142966 /FEA=EST /DB_XREF=gi:1712344 /DB_XREF=est:zl43b05.s1 /CLONE=IMAGE:504657 /UG=Hs.279849 KIAA0438 gene product /FL=gb:AB007898.1 gb:NM_014819.1 AA142966 "praja ring finger 2, E3 ubiquitin protein ligase" PJA2 9867 NM_014819 0007616 // long-term memory // inferred from sequence or structural similarity /// 0010738 // regulation of protein kinase A signaling // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from mutant phenotype /// 0034237 // protein kinase A regulatory subunit binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 201134_x_at NM_001867 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001867.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIc (COX7C), mRNA. /FEA=mRNA /GEN=COX7C /PROD=cytochrome c oxidase subunit VIIc /DB_XREF=gi:4502992 /UG=Hs.3462 cytochrome c oxidase subunit VIIc /FL=gb:BC001005.1 gb:NM_001867.1" NM_001867 cytochrome c oxidase subunit VIIc COX7C 1350 NM_001867 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201135_at NM_004092 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004092.2 /DEF=Homo sapiens enoyl Coenzyme A hydratase, short chain, 1, mitochondrial (ECHS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ECHS1 /PROD=mitochondrial short-chain enoyl-coenzyme Ahydratase 1 precursor /DB_XREF=gi:12707569 /UG=Hs.76394 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial /FL=gb:NM_004092.2 gb:D13900.1" NM_004092 "enoyl CoA hydratase, short chain, 1, mitochondrial" ECHS1 1892 NM_004092 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation 201136_at NM_002668 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002668.1 /DEF=Homo sapiens proteolipid protein 2 (colonic epithelium-enriched) (PLP2), mRNA. /FEA=mRNA /GEN=PLP2 /PROD=proteolipid protein 2 (colonicepithelium-enriched) /DB_XREF=gi:4505892 /UG=Hs.77422 proteolipid protein 2 (colonic epithelium-enriched) /FL=gb:L09604.1 gb:NM_002668.1" NM_002668 proteolipid protein 2 (colonic epithelium-enriched) PLP2 5355 NM_002668 0006811 // ion transport // traceable author statement /// 0006935 // chemotaxis // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015075 // ion transmembrane transporter activity // traceable author statement /// 0019956 // chemokine binding // inferred from physical interaction 201137_s_at NM_002121 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002121.1 /DEF=Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mRNA. /FEA=mRNA /GEN=HLA-DPB1 /PROD=major histocompatibility complex, class II, DPbeta 1 /DB_XREF=gi:4504404 /UG=Hs.814 major histocompatibility complex, class II, DP beta 1 /FL=gb:J03041.1 gb:M57466.1 gb:M83664.1 gb:NM_002121.1 gb:M28200.1 gb:M28202.1" NM_002121 "major histocompatibility complex, class II, DP beta 1" HLA-DPB1 3115 NM_002121 /// XM_006715077 /// XM_006715078 /// XM_006725039 /// XM_006725040 /// XM_006725698 /// XM_006725699 /// XM_006725816 /// XM_006725817 /// XM_006725907 /// XM_006725908 /// XM_006725997 /// XM_006725998 /// XM_006726087 /// XM_006726088 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from mutant phenotype /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay 201138_s_at BG532929 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG532929 /FEA=EST /DB_XREF=gi:13524468 /DB_XREF=est:602580582F1 /CLONE=IMAGE:4718180 /UG=Hs.83715 Sjogren syndrome antigen B (autoantigen La) /FL=gb:NM_003142.1 gb:BC001289.1 gb:J04205.1 BG532929 Sjogren syndrome antigen B (autoantigen La) SSB 6741 NM_001294145 /// NM_003142 /// XM_005246811 0006396 // RNA processing // inferred from electronic annotation /// 0006400 // tRNA modification // traceable author statement /// 0008334 // histone mRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201139_s_at NM_003142 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003142.1 /DEF=Homo sapiens Sjogren syndrome antigen B (autoantigen La) (SSB), mRNA. /FEA=mRNA /GEN=SSB /PROD=autoantigen La /DB_XREF=gi:10835066 /UG=Hs.83715 Sjogren syndrome antigen B (autoantigen La) /FL=gb:NM_003142.1 gb:BC001289.1 gb:J04205.1" NM_003142 Sjogren syndrome antigen B (autoantigen La) SSB 6741 NM_001294145 /// NM_003142 /// XM_005246811 0006396 // RNA processing // inferred from electronic annotation /// 0006400 // tRNA modification // traceable author statement /// 0008334 // histone mRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201140_s_at NM_004583 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004583.1 /DEF=Homo sapiens RAB5C, member RAS oncogene family (RAB5C), mRNA. /FEA=mRNA /GEN=RAB5C /PROD=RAB5C, member RAS oncogene family /DB_XREF=gi:4759019 /UG=Hs.479 RAB5C, member RAS oncogene family /FL=gb:NM_004583.1 gb:U11293.1 gb:U18420.1 gb:AF141304.1" NM_004583 "RAB5C, member RAS oncogene family" RAB5C 5878 NM_001252039 /// NM_004583 /// NM_201434 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 201141_at NM_002510 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002510.1 /DEF=Homo sapiens glycoprotein (transmembrane) nmb (GPNMB), mRNA. /FEA=mRNA /GEN=GPNMB /PROD=glycoprotein (transmembrane) nmb /DB_XREF=gi:4505404 /UG=Hs.82226 glycoprotein (transmembrane) nmb /FL=gb:AF322909.1 gb:NM_002510.1" NM_002510 glycoprotein (transmembrane) nmb GPNMB 10457 NM_001005340 /// NM_002510 /// XM_005249578 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 201142_at AA577698 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA577698 /FEA=EST /DB_XREF=gi:2355882 /DB_XREF=est:nn22h05.s1 /CLONE=IMAGE:1084665 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1" AA577698 "eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" EIF2S1 1965 NM_004094 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201143_s_at BC002513 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002513.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ), clone MGC:1511, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 2,subunit 1 (alpha, 35kD ) /DB_XREF=gi:12803384 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1" BC002513 "eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" EIF2S1 1965 NM_004094 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201144_s_at NM_004094 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004094.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) (EIF2S1), mRNA. /FEA=mRNA /GEN=EIF2S1 /PROD=eukaryotic translation initiation factor 2,subunit 1 (alpha, 35kD ) /DB_XREF=gi:4758255 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1" NM_004094 "eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" EIF2S1 1965 NM_004094 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201145_at NM_006118 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006118.2 /DEF=Homo sapiens HS1 binding protein (HAX1), mRNA. /FEA=mRNA /GEN=HAX1 /PROD=HS1 binding protein /DB_XREF=gi:13435355 /UG=Hs.15318 HS1 binding protein /FL=gb:NM_006118.2 gb:BC005240.1 gb:U68566.1" NM_006118 HCLS1 associated protein X-1 HAX1 10456 NM_001018837 /// NM_006118 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0030833 // regulation of actin filament polymerization // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0071345 // cellular response to cytokine stimulus // inferred from mutant phenotype /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019966 // interleukin-1 binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from direct assay 201146_at NM_006164 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006164.1 /DEF=Homo sapiens nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), mRNA. /FEA=mRNA /GEN=NFE2L2 /PROD=nuclear factor (erythroid-derived 2)-like 2 /DB_XREF=gi:5453775 /UG=Hs.155396 nuclear factor (erythroid-derived 2)-like 2 /FL=gb:NM_006164.1" NM_006164 "nuclear factor, erythroid 2-like 2" NFE2L2 4780 NM_001145412 /// NM_001145413 /// NM_006164 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from mutant phenotype /// 2000121 // regulation of removal of superoxide radicals // inferred from electronic annotation /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201147_s_at BF347089 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF347089 /FEA=EST /DB_XREF=gi:11294684 /DB_XREF=est:602020842F1 /CLONE=IMAGE:4156354 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2" BF347089 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201148_s_at AW338933 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW338933 /FEA=EST /DB_XREF=gi:6835559 /DB_XREF=est:ha68g07.x1 /CLONE=IMAGE:2878908 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2" AW338933 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201149_s_at U67195 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U67195.1 /DEF=Human tissue inhibitor of metalloproteinase-3 mRNA, complete cds. /FEA=mRNA /PROD=tissue inhibitor of metalloproteinase-3 /DB_XREF=gi:1519557 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2" U67195 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201150_s_at NM_000362 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000362.2 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) (TIMP3), mRNA. /FEA=mRNA /GEN=TIMP3 /PROD=tissue inhibitor of metalloproteinase 3precursor /DB_XREF=gi:9257248 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2" NM_000362 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007601 // visual perception // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201151_s_at BF512200 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF512200 /FEA=EST /DB_XREF=gi:11597379 /DB_XREF=est:UI-H-BI3-alq-d-11-0-UI.s1 /CLONE=IMAGE:3068228 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 BF512200 muscleblind-like splicing regulator 1 MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 /// XM_005247457 /// XM_005247458 /// XM_005247459 /// XM_005247460 /// XM_005247461 /// XM_005247462 /// XM_005247463 /// XM_005247464 /// XM_005247465 /// XM_005247466 /// XM_005247467 /// XM_005247468 /// XM_005247469 /// XM_005247470 /// XM_005247471 /// XM_005247472 /// XM_005247473 /// XM_005247474 /// XM_005247475 /// XM_005247476 /// XM_005247477 /// XM_006713639 /// XM_006713640 /// XM_006713641 "0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201152_s_at N31913 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N31913 /FEA=EST /DB_XREF=gi:1152312 /DB_XREF=est:yy21f10.s1 /CLONE=IMAGE:271915 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 N31913 muscleblind-like splicing regulator 1 MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 /// XM_005247457 /// XM_005247458 /// XM_005247459 /// XM_005247460 /// XM_005247461 /// XM_005247462 /// XM_005247463 /// XM_005247464 /// XM_005247465 /// XM_005247466 /// XM_005247467 /// XM_005247468 /// XM_005247469 /// XM_005247470 /// XM_005247471 /// XM_005247472 /// XM_005247473 /// XM_005247474 /// XM_005247475 /// XM_005247476 /// XM_005247477 /// XM_006713639 /// XM_006713640 /// XM_006713641 "0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201153_s_at NM_021038 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021038.1 /DEF=Homo sapiens muscleblind (Drosophila)-like (MBNL), mRNA. /FEA=mRNA /GEN=MBNL /PROD=muscleblind (Drosophila)-like /DB_XREF=gi:10518339 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1" NM_021038 muscleblind-like splicing regulator 1 MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 /// XM_005247457 /// XM_005247458 /// XM_005247459 /// XM_005247460 /// XM_005247461 /// XM_005247462 /// XM_005247463 /// XM_005247464 /// XM_005247465 /// XM_005247466 /// XM_005247467 /// XM_005247468 /// XM_005247469 /// XM_005247470 /// XM_005247471 /// XM_005247472 /// XM_005247473 /// XM_005247474 /// XM_005247475 /// XM_005247476 /// XM_005247477 /// XM_006713639 /// XM_006713640 /// XM_006713641 "0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201154_x_at NM_000968 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000968.1 /DEF=Homo sapiens ribosomal protein L4 (RPL4), mRNA. /FEA=mRNA /GEN=RPL4 /PROD=ribosomal protein L4 /DB_XREF=gi:4506652 /UG=Hs.286 ribosomal protein L4 /FL=gb:BC001365.1 gb:L20868.1 gb:D23660.1 gb:NM_000968.1" NM_000968 "ribosomal protein L4 /// small nucleolar RNA, C/D box 16 /// small nucleolar RNA, C/D box 18A /// small nucleolar RNA, C/D box 18B /// small nucleolar RNA, C/D box 18C" RPL4 /// SNORD16 /// SNORD18A /// SNORD18B /// SNORD18C 6124 /// 595097 /// 595098 /// 595099 /// 595100 NM_000968 /// NR_002440 /// NR_002441 /// NR_002442 /// NR_002443 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201155_s_at NM_014874 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014874.1 /DEF=Homo sapiens KIAA0214 gene product (KIAA0214), mRNA. /FEA=mRNA /GEN=KIAA0214 /PROD=KIAA0214 gene product /DB_XREF=gi:7662003 /UG=Hs.3363 KIAA0214 gene product /FL=gb:D86987.1 gb:AF036536.1 gb:NM_014874.1" NM_014874 mitofusin 2 MFN2 9927 NM_001127660 /// NM_014874 /// XM_005263543 /// XM_005263545 /// XM_005263547 /// XM_005263548 0001825 // blastocyst formation // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008053 // mitochondrial fusion // inferred from mutant phenotype /// 0008053 // mitochondrial fusion // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051646 // mitochondrion localization // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031306 // intrinsic component of mitochondrial outer membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201156_s_at AF141304 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF141304.1 /DEF=Homo sapiens small GTPase (RAB5C) mRNA, complete cds. /FEA=CDS /GEN=RAB5C /PROD=small GTPase /DB_XREF=gi:7672664 /UG=Hs.479 RAB5C, member RAS oncogene family /FL=gb:NM_004583.1 gb:U11293.1 gb:U18420.1 gb:AF141304.1" AF141304 "RAB5C, member RAS oncogene family" RAB5C 5878 NM_001252039 /// NM_004583 /// NM_201434 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 201157_s_at AF020500 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF020500.1 /DEF=Homo sapiens myristoyl CoA:protein N-myristoyltransferase mRNA, complete cds. /FEA=CDS /PROD=myristoyl CoA:protein N-myristoyltransferase /DB_XREF=gi:2760893 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1" AF020500 N-myristoyltransferase 1 NMT1 4836 NM_021079 /// XM_005257421 /// XM_005257422 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay "0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019107 // myristoyltransferase activity // inferred from electronic annotation" 201158_at AI570834 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI570834 /FEA=EST /DB_XREF=gi:4534208 /DB_XREF=est:tr67g09.x1 /CLONE=IMAGE:2223424 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1 AI570834 N-myristoyltransferase 1 NMT1 4836 NM_021079 /// XM_005257421 /// XM_005257422 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay "0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019107 // myristoyltransferase activity // inferred from electronic annotation" 201159_s_at NM_021079 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021079.1 /DEF=Homo sapiens N-myristoyltransferase 1 (NMT1), mRNA. /FEA=mRNA /GEN=NMT1 /PROD=N-myristoyltransferase 1 /DB_XREF=gi:10835072 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1" NM_021079 N-myristoyltransferase 1 NMT1 4836 NM_021079 /// XM_005257421 /// XM_005257422 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0009249 // protein lipoylation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay "0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019107 // myristoyltransferase activity // inferred from electronic annotation" 201160_s_at AL556190 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL556190 /FEA=EST /DB_XREF=gi:12898634 /DB_XREF=est:AL556190 /CLONE=CS0DK011YH09 (5 prime) /UG=Hs.1139 cold shock domain protein A /FL=gb:NM_003651.1 AL556190 Y box binding protein 3 YBX3 8531 NM_001145426 /// NM_003651 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0060547 // negative regulation of necrotic cell death // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred by curator /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071474 // cellular hyperosmotic response // inferred from mutant phenotype /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from mutant phenotype /// 2000767 // positive regulation of cytoplasmic translation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0017048 // Rho GTPase binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201161_s_at NM_003651 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003651.1 /DEF=Homo sapiens cold shock domain protein A (CSDA), mRNA. /FEA=mRNA /GEN=CSDA /PROD=cold shock domain protein A /DB_XREF=gi:4503070 /UG=Hs.1139 cold shock domain protein A /FL=gb:NM_003651.1" NM_003651 Y box binding protein 3 YBX3 8531 NM_001145426 /// NM_003651 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0060547 // negative regulation of necrotic cell death // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred by curator /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071474 // cellular hyperosmotic response // inferred from mutant phenotype /// 1902219 // negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress // inferred from mutant phenotype /// 2000767 // positive regulation of cytoplasmic translation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201162_at NM_001553 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001553.1 /DEF=Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), mRNA. /FEA=mRNA /GEN=IGFBP7 /PROD=insulin-like growth factor binding protein 7 /DB_XREF=gi:4504618 /UG=Hs.119206 insulin-like growth factor binding protein 7 /FL=gb:L19182.1 gb:NM_001553.1" NM_001553 insulin-like growth factor binding protein 7 IGFBP7 3490 NM_001253835 /// NM_001553 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051414 // response to cortisol // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201163_s_at NM_001553 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001553.1 /DEF=Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), mRNA. /FEA=mRNA /GEN=IGFBP7 /PROD=insulin-like growth factor binding protein 7 /DB_XREF=gi:4504618 /UG=Hs.119206 insulin-like growth factor binding protein 7 /FL=gb:L19182.1 gb:NM_001553.1" NM_001553 insulin-like growth factor binding protein 7 IGFBP7 3490 NM_001253835 /// NM_001553 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051414 // response to cortisol // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201164_s_at BG474429 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG474429 /FEA=EST /DB_XREF=gi:13406706 /DB_XREF=est:602517152F1 /CLONE=IMAGE:4648765 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 BG474429 pumilio RNA-binding family member 1 PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201165_s_at BE670915 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE670915 /FEA=EST /DB_XREF=gi:10031456 /DB_XREF=est:7e43a09.x1 /CLONE=IMAGE:3285208 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 BE670915 pumilio RNA-binding family member 1 PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201166_s_at NM_014676 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014676.1 /DEF=Homo sapiens pumilio (Drosophila) homolog 1 (PUM1), mRNA. /FEA=mRNA /GEN=PUM1 /PROD=pumilio (Drosophila) homolog 1 /DB_XREF=gi:13491165 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1" NM_014676 pumilio RNA-binding family member 1 PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201167_x_at D13989 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D13989.1 /DEF=Human rho GDI mRNA, complete cds. /FEA=mRNA /PROD=human rho GDI /DB_XREF=gi:285978 /UG=Hs.159161 Rho GDP dissociation inhibitor (GDI) alpha /FL=gb:D13989.1 gb:M97579.1 gb:NM_004309.1" D13989 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_001185077 /// NM_001185078 /// NM_004309 0006928 // cellular component movement // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201168_x_at NM_004309 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004309.1 /DEF=Homo sapiens Rho GDP dissociation inhibitor (GDI) alpha (ARHGDIA), mRNA. /FEA=mRNA /GEN=ARHGDIA /PROD=Rho GDP dissociation inhibitor (GDI) alpha /DB_XREF=gi:4757767 /UG=Hs.159161 Rho GDP dissociation inhibitor (GDI) alpha /FL=gb:D13989.1 gb:M97579.1 gb:NM_004309.1" NM_004309 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_001185077 /// NM_001185078 /// NM_004309 0006928 // cellular component movement // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement /// 0050772 // positive regulation of axonogenesis // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0071526 // semaphorin-plexin signaling pathway // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201169_s_at BG326045 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG326045 /FEA=EST /DB_XREF=gi:13132482 /DB_XREF=est:602424821F1 /CLONE=IMAGE:4562789 /UG=Hs.171825 basic helix-loop-helix domain containing, class B, 2 /FL=gb:AB004066.1 gb:NM_003670.1" BG326045 "basic helix-loop-helix family, member e40" BHLHE40 8553 NM_003670 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043426 // MRF binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201170_s_at NM_003670 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003670.1 /DEF=Homo sapiens basic helix-loop-helix domain containing, class B, 2 (BHLHB2), mRNA. /FEA=mRNA /GEN=BHLHB2 /PROD=differentiated embryo chondrocyte expressed gene1 /DB_XREF=gi:4503298 /UG=Hs.171825 basic helix-loop-helix domain containing, class B, 2 /FL=gb:AB004066.1 gb:NM_003670.1" NM_003670 "basic helix-loop-helix family, member e40" BHLHE40 8553 NM_003670 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043426 // MRF binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201171_at NM_003945 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:NM_003945.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD (ATP6H), mRNA. /FEA=mRNA /GEN=ATP6H /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 9kD /DB_XREF=gi:4502318 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD /FL=gb:NM_003945.1" NM_003945 "ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1" ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation" "0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 201172_x_at NM_003945 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003945.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD (ATP6H), mRNA. /FEA=mRNA /GEN=ATP6H /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 9kD /DB_XREF=gi:4502318 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD /FL=gb:NM_003945.1" NM_003945 "ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1" ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007035 // vacuolar acidification // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0016049 // cell growth // inferred from genetic interaction /// 0033572 // transferrin transport // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation" "0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from sequence or structural similarity /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 201173_x_at NM_006600 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006600.1 /DEF=Homo sapiens nuclear distribution gene C (A.nidulans) homolog (NUDC), mRNA. /FEA=mRNA /GEN=NUDC /PROD=nuclear distribution gene C (A.nidulans)homolog /DB_XREF=gi:5729952 /UG=Hs.263812 nuclear distribution gene C (A.nidulans) homolog /FL=gb:BC002399.1 gb:BC003132.1 gb:AB019408.1 gb:AF130736.1 gb:AF125465.1 gb:AF100760.1 gb:NM_006600.1" NM_006600 nudC nuclear distribution protein NUDC 10726 NM_006600 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201174_s_at NM_018975 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018975.1 /DEF=Homo sapiens TRF2-interacting telomeric RAP1 protein (RAP1), mRNA. /FEA=mRNA /GEN=RAP1 /PROD=TRF2-interacting telomeric RAP1 protein /DB_XREF=gi:9507032 /UG=Hs.274428 TRF2-interacting telomeric RAP1 protein /FL=gb:BC004465.1 gb:AF262988.1 gb:NM_018975.1" NM_018975 "telomeric repeat binding factor 2, interacting protein" TERF2IP 54386 NM_018975 "0000723 // telomere maintenance // inferred from direct assay /// 0000723 // telomere maintenance // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from sequence or structural similarity /// 0010833 // telomere maintenance via telomere lengthening // inferred from sequence or structural similarity /// 0031848 // protection from non-homologous end joining at telomere // inferred from mutant phenotype /// 0031848 // protection from non-homologous end joining at telomere // inferred from sequence or structural similarity /// 0032205 // negative regulation of telomere maintenance // inferred from direct assay /// 0032205 // negative regulation of telomere maintenance // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0048239 // negative regulation of DNA recombination at telomere // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype" "0000228 // nuclear chromosome // traceable author statement /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from sequence or structural similarity /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030870 // Mre11 complex // inferred from direct assay" 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // traceable author statement 201175_at NM_015959 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015959.1 /DEF=Homo sapiens CGI-31 protein (LOC51075), mRNA. /FEA=mRNA /GEN=LOC51075 /PROD=CGI-31 protein /DB_XREF=gi:7705725 /UG=Hs.279861 CGI-31 protein /FL=gb:AF059753.1 gb:BC000666.1 gb:AF132965.1 gb:NM_015959.1" NM_015959 thioredoxin-related transmembrane protein 2 TMX2 51075 NM_001144012 /// NM_015959 /// NR_026593 /// NR_037645 0045454 // cell redox homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201176_s_at NM_001655 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001655.2 /DEF=Homo sapiens archain 1 (ARCN1), mRNA. /FEA=mRNA /GEN=ARCN1 /PROD=archain /DB_XREF=gi:11863153 /UG=Hs.33642 archain 1 /FL=gb:NM_001655.2" NM_001655 archain 1 ARCN1 372 NM_001142281 /// NM_001655 /// XM_005271542 "0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0021691 // cerebellar Purkinje cell layer maturation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201177_s_at NM_005499 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005499.1 /DEF=Homo sapiens SUMO-1 activating enzyme subunit 2 (UBA2), mRNA. /FEA=mRNA /GEN=UBA2 /PROD=SUMO-1 activating enzyme subunit 2 /DB_XREF=gi:4885648 /UG=Hs.4311 SUMO-1 activating enzyme subunit 2 /FL=gb:BC003153.1 gb:U35832.1 gb:AF090384.1 gb:AF079566.1 gb:AF110957.1 gb:NM_005499.1 gb:AL136905.1" NM_005499 ubiquitin-like modifier activating enzyme 2 UBA2 10054 NM_005499 /// XM_005258403 /// XM_005258404 /// XM_006722962 0006464 // cellular protein modification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // traceable author statement /// 0019950 // SMT3-dependent protein catabolic process // not recorded /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0031510 // SUMO activating enzyme complex // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019948 // SUMO activating enzyme activity // inferred from direct assay /// 0019948 // SUMO activating enzyme activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201178_at NM_012179 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012179.1 /DEF=Homo sapiens F-box only protein 7 (FBXO7), mRNA. /FEA=mRNA /GEN=FBXO7 /PROD=F-box only protein 7 /DB_XREF=gi:7106310 /UG=Hs.5912 F-box only protein 7 /FL=gb:AF129537.1 gb:NM_012179.1 gb:AF233225.1" NM_012179 F-box protein 7 FBXO7 25793 NM_001033024 /// NM_001257990 /// NM_012179 0000422 // mitochondrion degradation // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201179_s_at J03005 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J03005.1 /DEF=Human alternative guanine nucleotide-binding regulatory protein (G) alpha-inhibitory-subunit mRNA, complete cds. /FEA=mRNA /GEN=GNAI1 /DB_XREF=gi:183183 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1" J03005 "guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" GNAI3 2773 NM_006496 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201180_s_at J03198 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J03198.1 /DEF=Human stimulatory G protein (of receptor-regulated K+ channels) alpha subunit mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183224 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1" J03198 "guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" GNAI3 2773 NM_006496 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201181_at NM_006496 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006496.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3), mRNA. /FEA=mRNA /GEN=GNAI3 /PROD=guanine nucleotide binding protein (G protein),alpha inhibiting activity polypeptide 3 /DB_XREF=gi:5729849 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1" NM_006496 "guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3" GNAI3 2773 NM_006496 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0051301 // cell division // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201182_s_at AI761771 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI761771 /FEA=EST /DB_XREF=gi:5177362 /DB_XREF=est:wi62b06.x1 /CLONE=IMAGE:2394803 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 AI761771 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 /// XM_005253668 /// XM_006718958 /// XM_006718959 /// XM_006718960 /// XM_006718961 /// XM_006718962 "0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051225 // spindle assembly // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 201183_s_at AI613273 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI613273 /FEA=EST /DB_XREF=gi:4622440 /DB_XREF=est:ty35e03.x1 /CLONE=IMAGE:2281084 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 AI613273 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 /// XM_005253668 /// XM_006718958 /// XM_006718959 /// XM_006718960 /// XM_006718961 /// XM_006718962 "0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051225 // spindle assembly // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 201184_s_at NM_001273 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001273.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 4 (CHD4), mRNA. /FEA=mRNA /GEN=CHD4 /PROD=chromodomain helicase DNA binding protein 4 /DB_XREF=gi:4557452 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1" NM_001273 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 /// XM_005253668 /// XM_006718958 /// XM_006718959 /// XM_006718960 /// XM_006718961 /// XM_006718962 "0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0051225 // spindle assembly // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 201185_at NM_002775 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002775.1 /DEF=Homo sapiens protease, serine, 11 (IGF binding) (PRSS11), mRNA. /FEA=mRNA /GEN=PRSS11 /PROD=protease, serine, 11 (IGF binding) /DB_XREF=gi:4506140 /UG=Hs.75111 protease, serine, 11 (IGF binding) /FL=gb:D87258.1 gb:NM_002775.1" NM_002775 HtrA serine peptidase 1 HTRA1 5654 NM_002775 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201186_at NM_002337 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002337.1 /DEF=Homo sapiens low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) (LRPAP1), mRNA. /FEA=mRNA /GEN=LRPAP1 /PROD=low density lipoprotein-relatedprotein-associated protein 1 (alpha-2-macroglobulinreceptor-associated protein 1) /DB_XREF=gi:4505020 /UG=Hs.75140 low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) /FL=gb:M63959.1 gb:NM_002337.1" NM_002337 low density lipoprotein receptor-related protein associated protein 1 LRPAP1 4043 NM_002337 /// NR_110005 0006457 // protein folding // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0016192 // vesicle-mediated transport // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 1900116 // extracellular negative regulation of signal transduction // inferred from direct assay /// 1900222 // negative regulation of beta-amyloid clearance // inferred from genetic interaction 0005576 // extracellular region // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031982 // vesicle // inferred from electronic annotation /// 0048237 // rough endoplasmic reticulum lumen // inferred from electronic annotation 0004873 // asialoglycoprotein receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0035473 // lipase binding // inferred from electronic annotation /// 0048019 // receptor antagonist activity // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction 201187_s_at BF001241 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF001241 /FEA=EST /DB_XREF=gi:10701516 /DB_XREF=est:7g96c02.x1 /CLONE=IMAGE:3314306 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1" BF001241 "inositol 1,4,5-trisphosphate receptor, type 3" ITPR3 3710 NM_002224 /// XM_006715091 /// XM_006715092 /// XM_006715093 0002082 // regulation of oxidative phosphorylation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from sequence or structural similarity "0000822 // inositol hexakisphosphate binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // inferred from sequence or structural similarity /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay" 201188_s_at D26351 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D26351.1 /DEF=Human mRNA for type 3 inositol 1,4,5-trisphosphate receptor, complete cds. /FEA=mRNA /PROD=human type 3 inositol 1,4,5-trisphosphatereceptor /DB_XREF=gi:450470 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1" D26351 "inositol 1,4,5-trisphosphate receptor, type 3" ITPR3 3710 NM_002224 /// XM_006715091 /// XM_006715092 /// XM_006715093 0002082 // regulation of oxidative phosphorylation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from sequence or structural similarity "0000822 // inositol hexakisphosphate binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // inferred from sequence or structural similarity /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay" 201189_s_at NM_002224 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002224.1 /DEF=Homo sapiens inositol 1,4,5-triphosphate receptor, type 3 (ITPR3), mRNA. /FEA=mRNA /GEN=ITPR3 /PROD=inositol 1,4,5-triphosphate receptor, type 3 /DB_XREF=gi:4504794 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1" NM_002224 "inositol 1,4,5-trisphosphate receptor, type 3" ITPR3 3710 NM_002224 /// XM_006715091 /// XM_006715092 /// XM_006715093 0002082 // regulation of oxidative phosphorylation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001014 // regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005903 // brush border // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043209 // myelin sheath // inferred from sequence or structural similarity /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from sequence or structural similarity "0000822 // inositol hexakisphosphate binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from direct assay /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0043533 // inositol 1,3,4,5 tetrakisphosphate binding // inferred from sequence or structural similarity /// 0070679 // inositol 1,4,5 trisphosphate binding // inferred from direct assay" 201190_s_at H15647 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:H15647 /FEA=EST /DB_XREF=gi:880467 /DB_XREF=est:ym27b09.s1 /CLONE=IMAGE:49287 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 H15647 "phosphatidylinositol transfer protein, alpha" PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070540 // stearic acid binding // inferred from electronic annotation 201191_at H15647 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:H15647 /FEA=EST /DB_XREF=gi:880467 /DB_XREF=est:ym27b09.s1 /CLONE=IMAGE:49287 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 H15647 "phosphatidylinositol transfer protein, alpha" PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070540 // stearic acid binding // inferred from electronic annotation 201192_s_at NM_006224 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006224.1 /DEF=Homo sapiens phosphotidylinositol transfer protein (PITPN), mRNA. /FEA=mRNA /GEN=PITPN /PROD=phosphotidylinositol transfer protein /DB_XREF=gi:5453907 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1" NM_006224 "phosphatidylinositol transfer protein, alpha" PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0070540 // stearic acid binding // inferred from electronic annotation 201193_at NM_005896 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005896.1 /DEF=Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble (IDH1), mRNA. /FEA=mRNA /GEN=IDH1 /PROD=isocitrate dehydrogenase 1 (NADP+), soluble /DB_XREF=gi:5174470 /UG=Hs.11223 isocitrate dehydrogenase 1 (NADP+), soluble /FL=gb:AF020038.1 gb:AF113917.1 gb:NM_005896.1 gb:AL136702.1" NM_005896 "isocitrate dehydrogenase 1 (NADP+), soluble" IDH1 3417 NM_001282386 /// NM_001282387 /// NM_005896 0006097 // glyoxylate cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006102 // isocitrate metabolic process // inferred from direct assay /// 0006103 // 2-oxoglutarate metabolic process // inferred from direct assay /// 0006103 // 2-oxoglutarate metabolic process // traceable author statement /// 0006740 // NADPH regeneration // traceable author statement /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000287 // magnesium ion binding // inferred from direct assay /// 0004450 // isocitrate dehydrogenase (NADP+) activity // not recorded /// 0004450 // isocitrate dehydrogenase (NADP+) activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201194_at NM_003009 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003009.1 /DEF=Homo sapiens selenoprotein W, 1 (SEPW1), mRNA. /FEA=mRNA /GEN=SEPW1 /PROD=selenoprotein W, 1 /DB_XREF=gi:4506886 /UG=Hs.14231 selenoprotein W, 1 /FL=gb:U67171.1 gb:AF015283.1 gb:NM_003009.1" NM_003009 "selenoprotein W, 1" SEPW1 6415 NM_003009 0045454 // cell redox homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0008430 // selenium binding // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation 201195_s_at AB018009 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB018009.1 /DEF=Homo sapiens mRNA for L-type amino acid transporter 1, complete cds. /FEA=mRNA /GEN=hLAT1 /PROD=L-type amino acid transporter 1 /DB_XREF=gi:5926731 /UG=Hs.184601 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 /FL=gb:AF077866.1 gb:AB018542.1 gb:AF104032.1 gb:NM_003486.1 gb:AB017908.1 gb:AB018009.1" AB018009 "solute carrier family 7 (amino acid transporter light chain, L system), member 5" SLC7A5 8140 NM_003486 /// XM_006721286 /// XM_006721287 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 201196_s_at M21154 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M21154.1 /DEF=Human S-adenosylmethionine decarboxylase mRNA, complete cds. /FEA=mRNA /GEN=AMD2 /DB_XREF=gi:178517 /UG=Hs.262476 S-adenosylmethionine decarboxylase 1 /FL=gb:BC000171.2 gb:M21154.1 gb:NM_001634.3" M21154 adenosylmethionine decarboxylase 1 AMD1 262 NM_001033059 /// NM_001287214 /// NM_001287215 /// NM_001287216 /// NM_001634 /// NR_109768 0006557 // S-adenosylmethioninamine biosynthetic process // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004014 // adenosylmethionine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 201197_at NM_001634 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001634.3 /DEF=Homo sapiens S-adenosylmethionine decarboxylase 1 (AMD1), mRNA. /FEA=mRNA /GEN=AMD1 /PROD=S-adenosylmethionine decarboxylase 1 precursor /DB_XREF=gi:5209326 /UG=Hs.262476 S-adenosylmethionine decarboxylase 1 /FL=gb:BC000171.2 gb:M21154.1 gb:NM_001634.3" NM_001634 adenosylmethionine decarboxylase 1 AMD1 262 NM_001033059 /// NM_001287214 /// NM_001287215 /// NM_001287216 /// NM_001634 /// NR_109768 0006557 // S-adenosylmethioninamine biosynthetic process // inferred from electronic annotation /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004014 // adenosylmethionine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 201198_s_at AI860431 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI860431 /FEA=EST /DB_XREF=gi:5514047 /DB_XREF=est:wl13h07.x1 /CLONE=IMAGE:2424829 /UG=Hs.3887 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 /FL=gb:D44466.1 gb:NM_002807.1" AI860431 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 1" PSMD1 5707 NM_001191037 /// NM_002807 /// NR_034059 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201199_s_at NM_002807 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002807.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 (PSMD1), mRNA. /FEA=mRNA /GEN=PSMD1 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 1 /DB_XREF=gi:4506224 /UG=Hs.3887 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 /FL=gb:D44466.1 gb:NM_002807.1" NM_002807 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 1" PSMD1 5707 NM_001191037 /// NM_002807 /// NR_034059 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201200_at NM_003851 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003851.1 /DEF=Homo sapiens cellular repressor of E1A-stimulated genes (CREG), mRNA. /FEA=mRNA /GEN=CREG /PROD=cellular repressor of E1A-stimulated genes /DB_XREF=gi:4503036 /UG=Hs.5710 cellular repressor of E1A-stimulated genes /FL=gb:AF084523.1 gb:NM_003851.1" NM_003851 cellular repressor of E1A-stimulated genes 1 CREG1 8804 NM_003851 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0010181 // FMN binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201201_at NM_000100 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000100.1 /DEF=Homo sapiens cystatin B (stefin B) (CSTB), mRNA. /FEA=mRNA /GEN=CSTB /PROD=cystatin B (stefin B) /DB_XREF=gi:4503116 /UG=Hs.695 cystatin B (stefin B) /FL=gb:BC003370.1 gb:L03558.1 gb:NM_000100.1" NM_000100 cystatin B (stefin B) CSTB 1476 NM_000100 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201202_at NM_002592 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002592.1 /DEF=Homo sapiens proliferating cell nuclear antigen (PCNA), mRNA. /FEA=mRNA /GEN=PCNA /PROD=proliferating cell nuclear antigen /DB_XREF=gi:4505640 /UG=Hs.78996 proliferating cell nuclear antigen /FL=gb:BC000491.1 gb:M15796.1 gb:NM_002592.1" NM_002592 proliferating cell nuclear antigen PCNA 5111 NM_002592 /// NM_182649 "0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006272 // leading strand elongation // not recorded /// 0006275 // regulation of DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0019985 // translesion synthesis // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032077 // positive regulation of deoxyribonuclease activity // inferred from direct assay /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0033993 // response to lipid // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030896 // checkpoint clamp complex // inferred from electronic annotation /// 0043596 // nuclear replication fork // inferred from direct assay /// 0043626 // PCNA complex // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070557 // PCNA-p21 complex // inferred from direct assay 0000701 // purine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030337 // DNA polymerase processivity factor activity // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0032139 // dinucleotide insertion or deletion binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0070182 // DNA polymerase binding // inferred from physical interaction 201203_s_at AI921320 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI921320 /FEA=EST /DB_XREF=gi:5657284 /DB_XREF=est:wo23c10.x1 /CLONE=IMAGE:2456178 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AI921320 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201204_s_at AA706065 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA706065 /FEA=EST /DB_XREF=gi:2715983 /DB_XREF=est:zf44f12.s1 /CLONE=IMAGE:379823 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AA706065 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201205_at AF006751 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF006751.1 /DEF=Homo sapiens ES130 mRNA, complete cds. /FEA=mRNA /PROD=ES130 /DB_XREF=gi:3299884 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1" AF006751 201206_s_at NM_004587 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004587.1 /DEF=Homo sapiens ribosome binding protein 1 (dog 180kD homolog) (RRBP1), mRNA. /FEA=mRNA /GEN=RRBP1 /PROD=ribosome binding protein 1 /DB_XREF=gi:4759055 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1" NM_004587 ribosome binding protein 1 RRBP1 6238 NM_001042576 /// NM_004587 0001649 // osteoblast differentiation // inferred from direct assay /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201207_at NM_021137 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021137.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 1 (endothelial) (TNFAIP1), mRNA. /FEA=mRNA /GEN=TNFAIP1 /PROD=tumor necrosis factor, alpha-induced protein 1(endothelial) /DB_XREF=gi:10863936 /UG=Hs.76090 tumor necrosis factor, alpha-induced protein 1 (endothelial) /FL=gb:NM_021137.1 gb:BC001643.1 gb:BC001949.1 gb:BC003694.1 gb:M80783.1" NM_021137 "tumor necrosis factor, alpha-induced protein 1 (endothelial)" TNFAIP1 7126 NM_021137 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from expression pattern /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 201208_s_at BC001643 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001643.1 /DEF=Homo sapiens, tumor necrosis factor, alpha-induced protein 1 (endothelial), clone MGC:2317, mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor, alpha-induced protein 1(endothelial) /DB_XREF=gi:12804470 /UG=Hs.76090 tumor necrosis factor, alpha-induced protein 1 (endothelial) /FL=gb:NM_021137.1 gb:BC001643.1 gb:BC001949.1 gb:BC003694.1 gb:M80783.1" BC001643 "tumor necrosis factor, alpha-induced protein 1 (endothelial)" TNFAIP1 7126 NM_021137 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006955 // immune response // inferred from expression pattern /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation 201209_at NM_004964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004964.2 /DEF=Homo sapiens histone deacetylase 1 (HDAC1), mRNA. /FEA=mRNA /GEN=HDAC1 /PROD=histone deacetylase 1 /DB_XREF=gi:13128859 /UG=Hs.88556 histone deacetylase 1 /FL=gb:BC000301.1 gb:U50079.1 gb:NM_004964.2 gb:D50405.1" NM_004964 histone deacetylase 1 HDAC1 3065 NM_004964 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006338 // chromatin remodeling // inferred by curator /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006476 // protein deacetylation // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009913 // epidermal cell differentiation // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // traceable author statement /// 0016575 // histone deacetylation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043922 // negative regulation by host of viral transcription // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0060789 // hair follicle placode formation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061198 // fungiform papilla formation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from direct assay /// 0070933 // histone H4 deacetylation // inferred from direct assay" 0000118 // histone deacetylase complex // traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0004407 // histone deacetylase activity // inferred from mutant phenotype /// 0004407 // histone deacetylase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0033558 // protein deacetylase activity // inferred from mutant phenotype /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 201210_at NM_001356 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001356.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 (DDX3), transcript variant 2, mRNA. /FEA=mRNA /GEN=DDX3 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /DB_XREF=gi:13514812 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /FL=gb:NM_001356.2 gb:U50553.1 gb:AF000982.1 gb:AF061337.1" NM_001356 "DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked" DDX3X 1654 NM_001193416 /// NM_001193417 /// NM_001356 /// NM_024005 "0002376 // immune system process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0009615 // response to virus // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034063 // stress granule assembly // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0035613 // RNA stem-loop binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 201211_s_at AF061337 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF061337.1 /DEF=Homo sapiens DEAD box RNA helicase DDX3 (DDX3) mRNA, complete cds. /FEA=mRNA /GEN=DDX3 /PROD=DEAD box RNA helicase DDX3 /DB_XREF=gi:3523149 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /FL=gb:NM_001356.2 gb:U50553.1 gb:AF000982.1 gb:AF061337.1" AF061337 "DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked" DDX3X 1654 NM_001193416 /// NM_001193417 /// NM_001356 /// NM_024005 "0002376 // immune system process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 0009615 // response to virus // inferred from direct assay /// 0010501 // RNA secondary structure unwinding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034063 // stress granule assembly // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071651 // positive regulation of chemokine (C-C motif) ligand 5 production // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0008190 // eukaryotic initiation factor 4E binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031369 // translation initiation factor binding // inferred from direct assay /// 0035613 // RNA stem-loop binding // inferred from direct assay /// 0043024 // ribosomal small subunit binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 201212_at D55696 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D55696.1 /DEF=Homo sapiens mRNA for cysteine protease, complete cds. /FEA=mRNA /PROD=cysteine protease /DB_XREF=gi:1890049 /UG=Hs.18069 protease, cysteine, 1 (legumain) /FL=gb:BC003061.1 gb:D55696.1 gb:NM_005606.1" D55696 legumain LGMN 5641 NM_001008530 /// NM_005606 /// XM_005267862 /// XM_005267863 0001101 // response to acid // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0003014 // renal system process // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from sequence or structural similarity /// 0008202 // steroid metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032801 // receptor catabolic process // inferred from sequence or structural similarity /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 1901185 // negative regulation of ERBB signaling pathway // inferred from sequence or structural similarity 0005764 // lysosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045177 // apical part of cell // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201213_at AI090331 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI090331 /FEA=EST /DB_XREF=gi:3429390 /DB_XREF=est:oy81f08.s1 /CLONE=IMAGE:1672263 /UG=Hs.36587 protein phosphatase 1, regulatory subunit 7 /FL=gb:BC000910.1 gb:NM_002712.1" AI090331 "protein phosphatase 1, regulatory subunit 7" PPP1R7 5510 NM_001282409 /// NM_001282410 /// NM_001282411 /// NM_001282412 /// NM_001282413 /// NM_001282414 /// NM_002712 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement 201214_s_at NM_002712 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002712.1 /DEF=Homo sapiens protein phosphatase 1, regulatory subunit 7 (PPP1R7), mRNA. /FEA=mRNA /GEN=PPP1R7 /PROD=protein phosphatase 1, regulatory subunit 7 /DB_XREF=gi:4506012 /UG=Hs.36587 protein phosphatase 1, regulatory subunit 7 /FL=gb:BC000910.1 gb:NM_002712.1" NM_002712 "protein phosphatase 1, regulatory subunit 7" PPP1R7 5510 NM_001282409 /// NM_001282410 /// NM_001282411 /// NM_001282412 /// NM_001282413 /// NM_001282414 /// NM_002712 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // non-traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement 201215_at NM_005032 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005032.2 /DEF=Homo sapiens plastin 3 (T isoform) (PLS3), mRNA. /FEA=mRNA /GEN=PLS3 /PROD=plastin 3 precursor /DB_XREF=gi:7549808 /UG=Hs.4114 plastin 3 (T isoform) /FL=gb:M22299.1 gb:NM_005032.2" NM_005032 plastin 3 PLS3 5358 NM_001136025 /// NM_001172335 /// NM_001282337 /// NM_001282338 /// NM_005032 0060348 // bone development // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201216_at NM_006817 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006817.2 /DEF=Homo sapiens endoplasmic reticulum lumenal protein (ERP28), mRNA. /FEA=mRNA /GEN=ERP28 /PROD=endoplasmic reticulum lumenal protein ERp28precursor /DB_XREF=gi:13124889 /UG=Hs.75841 endoplasmic reticulum lumenal protein /FL=gb:NM_006817.2" NM_006817 endoplasmic reticulum protein 29 ERP29 10961 NM_001034025 /// NM_006817 0006457 // protein folding // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0009306 // protein secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201217_x_at NM_000967 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000967.1 /DEF=Homo sapiens ribosomal protein L3 (RPL3), mRNA. /FEA=mRNA /GEN=RPL3 /PROD=ribosomal protein L3 /DB_XREF=gi:4506648 /UG=Hs.119598 ribosomal protein L3 /FL=gb:BC002408.1 gb:BC004323.1 gb:NM_000967.1" NM_000967 "RNA, U86 small nucleolar /// ribosomal protein L3 /// small nucleolar RNA, C/D box 83B" RNU86 /// RPL3 /// SNORD83B 6122 /// 116936 /// 116938 NM_000967 /// NM_001033853 /// NR_000026 /// NR_000028 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201218_at N23018 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N23018 /FEA=EST /DB_XREF=gi:1137168 /DB_XREF=est:yx65d12.s1 /CLONE=IMAGE:266615 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 N23018 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation "0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201219_at AW269836 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW269836 /FEA=EST /DB_XREF=gi:6656866 /DB_XREF=est:xv45h03.x1 /CLONE=IMAGE:2816117 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 AW269836 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation "0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201220_x_at NM_001329 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001329.1 /DEF=Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 1, mRNA. /FEA=mRNA /GEN=CTBP2 /PROD=C-terminal binding protein 2, isoform 1 /DB_XREF=gi:4557498 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1" NM_001329 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001290214 /// NM_001290215 /// NM_001329 /// NM_022802 /// XM_005269561 /// XM_005269562 /// XM_005269563 /// XM_005269564 /// XM_005269565 /// XM_005269567 /// XM_005269568 /// XM_005269569 /// XM_005269570 /// XM_005269571 /// XM_005269572 /// XM_006717641 /// XM_006717642 /// XM_006717643 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation "0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201221_s_at NM_003089 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003089.1 /DEF=Homo sapiens small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen) (SNRP70), mRNA. /FEA=mRNA /GEN=SNRP70 /PROD=small nuclear ribonucleoprotein 70kD polypeptide(RNP antigen) /DB_XREF=gi:4507118 /UG=Hs.174051 small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen) /FL=gb:BC000342.1 gb:M22636.1 gb:NM_003089.1" NM_003089 small nuclear ribonucleoprotein 70kDa (U1) SNRNP70 6625 NM_001009820 /// NM_003089 /// XM_005259177 /// XM_005259178 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032608 // interferon-beta production // inferred from electronic annotation /// 0032608 // interferon-beta production // inferred from sequence or structural similarity /// 0034340 // response to type I interferon // inferred from electronic annotation /// 0034340 // response to type I interferon // inferred from sequence or structural similarity /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0070534 // protein K63-linked ubiquitination // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from sequence or structural similarity" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201222_s_at AL527365 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL527365 /FEA=EST /DB_XREF=gi:12790858 /DB_XREF=est:AL527365 /CLONE=CS0DC021YG08 (5 prime) /UG=Hs.178658 RAD23 (S. cerevisiae) homolog B /FL=gb:NM_002874.1 gb:D21090.1 AL527365 RAD23 homolog B (S. cerevisiae) RAD23B 5887 NM_001244713 /// NM_001244724 /// NM_002874 "0000715 // nucleotide-excision repair, DNA damage recognition // inferred from direct assay /// 0000715 // nucleotide-excision repair, DNA damage recognition // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0071942 // XPC complex // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 201223_s_at NM_002874 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002874.1 /DEF=Homo sapiens RAD23 (S. cerevisiae) homolog B (RAD23B), mRNA. /FEA=mRNA /GEN=RAD23B /PROD=RAD23 (S. cerevisiae) homolog B /DB_XREF=gi:4506386 /UG=Hs.178658 RAD23 (S. cerevisiae) homolog B /FL=gb:NM_002874.1 gb:D21090.1" NM_002874 RAD23 homolog B (S. cerevisiae) RAD23B 5887 NM_001244713 /// NM_001244724 /// NM_002874 "0000715 // nucleotide-excision repair, DNA damage recognition // inferred from direct assay /// 0000715 // nucleotide-excision repair, DNA damage recognition // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0071942 // XPC complex // inferred from direct assay 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 201224_s_at AU147713 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU147713 /FEA=EST /DB_XREF=gi:11009234 /DB_XREF=est:AU147713 /CLONE=MAMMA1001474 /UG=Hs.18192 SerArg-related nuclear matrix protein (plenty of prolines 101-like) /FL=gb:AF048977.1 gb:NM_005839.1 AU147713 serine/arginine repetitive matrix 1 SRRM1 10250 NM_005839 /// XM_005245717 /// XM_005245718 /// XM_005245719 /// XM_005245720 /// XM_005245721 /// XM_005245722 /// XR_241182 /// XR_241183 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201225_s_at NM_005839 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005839.1 /DEF=Homo sapiens SerArg-related nuclear matrix protein (plenty of prolines 101-like) (SRM160), mRNA. /FEA=mRNA /GEN=SRM160 /PROD=SerArg-related nuclear matrix protein (plentyof prolines 101-like) /DB_XREF=gi:5032118 /UG=Hs.18192 SerArg-related nuclear matrix protein (plenty of prolines 101-like) /FL=gb:AF048977.1 gb:NM_005839.1" NM_005839 serine/arginine repetitive matrix 1 SRRM1 10250 NM_005839 /// XM_005245717 /// XM_005245718 /// XM_005245719 /// XM_005245720 /// XM_005245721 /// XM_005245722 /// XR_241182 /// XR_241183 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201226_at NM_005004 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005004.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) (NDUFB8), mRNA. /FEA=mRNA /GEN=NDUFB8 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 8 (19kD, ASHI) /DB_XREF=gi:4826853 /UG=Hs.198273 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) /FL=gb:BC000466.1 gb:AF044958.1 gb:AF077028.1 gb:NM_005004.1 gb:AL080056.1" NM_005004 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa" NDUFB8 4714 NM_001284367 /// NM_001284368 /// NM_005004 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 201227_s_at NM_005004 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005004.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) (NDUFB8), mRNA. /FEA=mRNA /GEN=NDUFB8 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 8 (19kD, ASHI) /DB_XREF=gi:4826853 /UG=Hs.198273 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) /FL=gb:BC000466.1 gb:AF044958.1 gb:AF077028.1 gb:NM_005004.1 gb:AL080056.1" NM_005004 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa" NDUFB8 4714 NM_001284367 /// NM_001284368 /// NM_005004 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 201228_s_at AW074830 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW074830 /FEA=EST /DB_XREF=gi:6029828 /DB_XREF=est:xa08a08.x1 /CLONE=IMAGE:2567702 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1 AW074830 ariadne RBR E3 ubiquitin protein ligase 2 ARIH2 10425 NM_006321 /// XM_005264798 /// XM_006712924 /// XM_006712925 /// XM_006712926 /// XM_006712927 /// XM_006712928 /// XM_006712929 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048588 // developmental cell growth // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201229_s_at BC000422 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000422.1 /DEF=Homo sapiens, ariadne (Drosophila) homolog 2, clone MGC:8671, mRNA, complete cds. /FEA=mRNA /PROD=ariadne (Drosophila) homolog 2 /DB_XREF=gi:12653306 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1" BC000422 ariadne RBR E3 ubiquitin protein ligase 2 ARIH2 10425 NM_006321 /// XM_005264798 /// XM_006712924 /// XM_006712925 /// XM_006712926 /// XM_006712927 /// XM_006712928 /// XM_006712929 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048588 // developmental cell growth // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201230_s_at NM_006321 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006321.1 /DEF=Homo sapiens ariadne (Drosophila) homolog 2 (ARIH2), mRNA. /FEA=mRNA /GEN=ARIH2 /PROD=ariadne (Drosophila) homolog 2 /DB_XREF=gi:5453556 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1" NM_006321 ariadne RBR E3 ubiquitin protein ligase 2 ARIH2 10425 NM_006321 /// XM_005264798 /// XM_006712924 /// XM_006712925 /// XM_006712926 /// XM_006712927 /// XM_006712928 /// XM_006712929 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048588 // developmental cell growth // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201231_s_at NM_001428 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001428.1 /DEF=Homo sapiens enolase 1, (alpha) (ENO1), mRNA. /FEA=mRNA /GEN=ENO1 /PROD=enolase 1, (alpha) /DB_XREF=gi:4503570 /UG=Hs.254105 enolase 1, (alpha) /FL=gb:BC001810.1 gb:BC004458.1 gb:M14328.1 gb:NM_001428.1" NM_001428 "enolase 1, (alpha)" ENO1 2023 NM_001201483 /// NM_001428 /// XM_006710433 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay" 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201232_s_at NM_002817 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002817.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (PSMD13), mRNA. /FEA=mRNA /GEN=PSMD13 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 13 /DB_XREF=gi:4506222 /UG=Hs.279554 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 /FL=gb:BC001100.1 gb:BC001747.1 gb:AB009398.1 gb:NM_002817.1 gb:AF083245.1 gb:AF107837.1" NM_002817 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 13" PSMD13 5719 NM_002817 /// NM_175932 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007127 // meiosis I // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201233_at NM_002817 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002817.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (PSMD13), mRNA. /FEA=mRNA /GEN=PSMD13 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 13 /DB_XREF=gi:4506222 /UG=Hs.279554 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 /FL=gb:BC001100.1 gb:BC001747.1 gb:AB009398.1 gb:NM_002817.1 gb:AF083245.1 gb:AF107837.1" NM_002817 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 13" PSMD13 5719 NM_002817 /// NM_175932 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007127 // meiosis I // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201234_at NM_004517 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004517.1 /DEF=Homo sapiens integrin-linked kinase (ILK), mRNA. /FEA=mRNA /GEN=ILK /PROD=integrin-linked kinase /DB_XREF=gi:4758605 /UG=Hs.6196 integrin-linked kinase /FL=gb:U40282.1 gb:NM_004517.1" NM_004517 integrin-linked kinase ILK 3611 NM_001014794 /// NM_001014795 /// NM_001278441 /// NM_001278442 /// NM_004517 /// XM_005252904 /// XM_005252905 "0001558 // regulation of cell growth // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction" 201235_s_at BG339064 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG339064 /FEA=EST /DB_XREF=gi:13145502 /DB_XREF=est:602436889F1 /CLONE=IMAGE:4554551 /UG=Hs.75462 BTG family, member 2 /FL=gb:U72649.1 gb:NM_006763.1" BG339064 "BTG family, member 2" BTG2 7832 NM_006763 "0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008306 // associative learning // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from electronic annotation" 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201236_s_at NM_006763 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006763.1 /DEF=Homo sapiens BTG family, member 2 (BTG2), mRNA. /FEA=mRNA /GEN=BTG2 /PROD=BTG family, member 2 /DB_XREF=gi:5802987 /UG=Hs.75462 BTG family, member 2 /FL=gb:U72649.1 gb:NM_006763.1" NM_006763 "BTG family, member 2" BTG2 7832 NM_006763 "0006281 // DNA repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006479 // protein methylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008306 // associative learning // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0021542 // dentate gyrus development // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from electronic annotation" 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201237_at AV685920 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AV685920 /FEA=EST /DB_XREF=gi:10287783 /DB_XREF=est:AV685920 /CLONE=GKCEGD05 /UG=Hs.75546 capping protein (actin filament) muscle Z-line, alpha 2 /FL=gb:BC005338.1 gb:NM_006136.1 gb:U03269.1" AV685920 "capping protein (actin filament) muscle Z-line, alpha 2" CAPZA2 830 NM_006136 0006461 // protein complex assembly // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201238_s_at BC005338 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005338.1 /DEF=Homo sapiens, capping protein (actin filament) muscle Z-line, alpha 2, clone MGC:12426, mRNA, complete cds. /FEA=mRNA /PROD=capping protein (actin filament) muscle Z-line,alpha 2 /DB_XREF=gi:13529130 /UG=Hs.75546 capping protein (actin filament) muscle Z-line, alpha 2 /FL=gb:BC005338.1 gb:NM_006136.1 gb:U03269.1" BC005338 "capping protein (actin filament) muscle Z-line, alpha 2" CAPZA2 830 NM_006136 0006461 // protein complex assembly // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201239_s_at BF530535 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF530535 /FEA=EST /DB_XREF=gi:11617898 /DB_XREF=est:602071788F1 /CLONE=IMAGE:4214660 /UG=Hs.77665 KIAA0102 gene product /FL=gb:D14658.1 gb:NM_014752.1 BF530535 signal peptidase complex subunit 2 homolog (S. cerevisiae) SPCS2 9789 NM_014752 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201240_s_at NM_014752 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014752.1 /DEF=Homo sapiens KIAA0102 gene product (KIAA0102), mRNA. /FEA=mRNA /GEN=KIAA0102 /PROD=KIAA0102 gene product /DB_XREF=gi:7661907 /UG=Hs.77665 KIAA0102 gene product /FL=gb:D14658.1 gb:NM_014752.1" NM_014752 signal peptidase complex subunit 2 homolog (S. cerevisiae) SPCS2 9789 NM_014752 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201241_at NM_004939 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004939.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 (DDX1), mRNA. /FEA=mRNA /GEN=DDX1 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 /DB_XREF=gi:4826685 /UG=Hs.78580 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 /FL=gb:X70649.1 gb:NM_004939.1" NM_004939 DEAD (Asp-Glu-Ala-Asp) box helicase 1 DDX1 1653 NM_004939 "0000245 // spliceosomal complex assembly // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006302 // double-strand break repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from expression pattern /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0071920 // cleavage body // inferred from direct assay /// 0072669 // tRNA-splicing ligase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from direct assay /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0008143 // poly(A) binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033677 // DNA/RNA helicase activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201242_s_at BC000006 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000006.1 /DEF=Homo sapiens, ATPase, Na+K+ transporting, beta 1 polypeptide, clone MGC:1798, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, Na+K+ transporting, beta 1 polypeptide /DB_XREF=gi:12652534 /UG=Hs.78629 ATPase, Na+K+ transporting, beta 1 polypeptide /FL=gb:BC000006.1 gb:NM_001677.1" BC000006 "ATPase, Na+/K+ transporting, beta 1 polypeptide" ATP1B1 481 NM_001001787 /// NM_001677 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay 201243_s_at NM_001677 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001677.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, beta 1 polypeptide (ATP1B1), mRNA. /FEA=mRNA /GEN=ATP1B1 /PROD=ATPase, Na+K+ transporting, beta 1 polypeptide /DB_XREF=gi:4502276 /UG=Hs.78629 ATPase, Na+K+ transporting, beta 1 polypeptide /FL=gb:BC000006.1 gb:NM_001677.1" NM_001677 "ATPase, Na+/K+ transporting, beta 1 polypeptide" ATP1B1 481 NM_001001787 /// NM_001677 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030001 // metal ion transport // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0023026 // MHC class II protein complex binding // inferred from direct assay 201244_s_at NM_002880 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002880.1 /DEF=Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1), mRNA. /FEA=mRNA /GEN=RAF1 /PROD=v-raf-1 murine leukemia viral oncogene homolog1 /DB_XREF=gi:4506400 /UG=Hs.85181 v-raf-1 murine leukemia viral oncogene homolog 1 /FL=gb:NM_002880.1" NM_002880 "Raf-1 proto-oncogene, serine/threonine kinase" RAF1 5894 NM_002880 /// XM_005265355 /// XM_005265357 /// XM_005265358 /// XM_005265359 /// XM_005265360 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007190 // activation of adenylate cyclase activity // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045104 // intermediate filament cytoskeleton organization // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071550 // death-inducing signaling complex assembly // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000145 // regulation of cell motility // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from physical interaction /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031143 // pseudopodium // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0031267 // small GTPase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation" 201245_s_at AL523776 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL523776 /FEA=EST /DB_XREF=gi:12787269 /DB_XREF=est:AL523776 /CLONE=CS0DC003YC23 (5 prime) /UG=Hs.108504 hypothetical protein FLJ20113 /FL=gb:NM_017670.1 AL523776 "uncharacterized LOC101927673 /// OTU deubiquitinase, ubiquitin aldehyde binding 1" LOC101927673 /// OTUB1 55611 /// 101927673 NM_017670 /// NR_003089 /// XR_247234 /// XR_247664 /// XR_252904 0002376 // immune system process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from direct assay /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019784 // NEDD8-specific protease activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay 201246_s_at NM_017670 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017670.1 /DEF=Homo sapiens hypothetical protein FLJ20113 (FLJ20113), mRNA. /FEA=mRNA /GEN=FLJ20113 /PROD=hypothetical protein FLJ20113 /DB_XREF=gi:8923113 /UG=Hs.108504 hypothetical protein FLJ20113 /FL=gb:NM_017670.1" NM_017670 "uncharacterized LOC101927673 /// OTU deubiquitinase, ubiquitin aldehyde binding 1" LOC101927673 /// OTUB1 55611 /// 101927673 NM_017670 /// NR_003089 /// XR_247234 /// XR_247664 /// XR_252904 0002376 // immune system process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from direct assay /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019784 // NEDD8-specific protease activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay 201247_at BE513151 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE513151 /FEA=EST /DB_XREF=gi:9720362 /DB_XREF=est:601171940F1 /CLONE=IMAGE:3545697 /UG=Hs.108689 sterol regulatory element binding transcription factor 2 /FL=gb:U02031.1 gb:NM_004599.1 BE513151 sterol regulatory element binding transcription factor 2 SREBF2 6721 NM_004599 /// NR_103834 /// XM_006724310 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0071499 // cellular response to laminar fluid shear stress // non-traceable author statement /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0000247 // C-8 sterol isomerase activity // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201248_s_at NM_004599 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004599.1 /DEF=Homo sapiens sterol regulatory element binding transcription factor 2 (SREBF2), mRNA. /FEA=mRNA /GEN=SREBF2 /PROD=sterol regulatory element binding transcriptionfactor 2 /DB_XREF=gi:4759169 /UG=Hs.108689 sterol regulatory element binding transcription factor 2 /FL=gb:U02031.1 gb:NM_004599.1" NM_004599 sterol regulatory element binding transcription factor 2 SREBF2 6721 NM_004599 /// NR_103834 /// XM_006724310 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0071499 // cellular response to laminar fluid shear stress // non-traceable author statement /// 0072368 // regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0000247 // C-8 sterol isomerase activity // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from direct assay 201249_at AI091047 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI091047 /FEA=EST /DB_XREF=gi:3430106 /DB_XREF=est:qa53b03.s1 /CLONE=IMAGE:1690445 /UG=Hs.169902 solute carrier family 2 (facilitated glucose transporter), member 1 /FL=gb:K03195.1 gb:NM_006516.1" AI091047 "solute carrier family 2 (facilitated glucose transporter), member 1" SLC2A1 6513 NM_006516 0005975 // carbohydrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042908 // xenobiotic transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070837 // dehydroascorbic acid transport // inferred from electronic annotation 0001939 // female pronucleus // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation /// 0033300 // dehydroascorbic acid transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042910 // xenobiotic transporter activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from direct assay /// 0055056 // D-glucose transmembrane transporter activity // inferred from electronic annotation 201250_s_at NM_006516 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006516.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 1 (SLC2A1), mRNA. /FEA=mRNA /GEN=SLC2A1 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 1 /DB_XREF=gi:5730050 /UG=Hs.169902 solute carrier family 2 (facilitated glucose transporter), member 1 /FL=gb:K03195.1 gb:NM_006516.1" NM_006516 "solute carrier family 2 (facilitated glucose transporter), member 1" SLC2A1 6513 NM_006516 0005975 // carbohydrate metabolic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from direct assay /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042908 // xenobiotic transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070837 // dehydroascorbic acid transport // inferred from electronic annotation 0001939 // female pronucleus // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation /// 0033300 // dehydroascorbic acid transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042910 // xenobiotic transporter activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from direct assay /// 0055056 // D-glucose transmembrane transporter activity // inferred from electronic annotation 201251_at NM_002654 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002654.1 /DEF=Homo sapiens pyruvate kinase, muscle (PKM2), mRNA. /FEA=mRNA /GEN=PKM2 /PROD=pyruvate kinase, muscle /DB_XREF=gi:4505838 /UG=Hs.198281 pyruvate kinase, muscle /FL=gb:BC000481.1 gb:M23725.1 gb:M26252.1 gb:NM_002654.1" NM_002654 "pyruvate kinase, muscle" PKM 5315 NM_001206796 /// NM_001206797 /// NM_001206798 /// NM_001206799 /// NM_002654 /// NM_182470 /// NM_182471 /// XM_005254443 /// XM_005254445 /// XM_006720570 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201252_at NM_006503 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006503.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), mRNA. /FEA=mRNA /GEN=PSMC4 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 4 /DB_XREF=gi:5729990 /UG=Hs.211594 proteasome (prosome, macropain) 26S subunit, ATPase, 4 /FL=gb:BC000343.1 gb:AF038965.1 gb:AF020736.1 gb:U27515.1 gb:NM_006503.1" NM_006503 "proteasome (prosome, macropain) 26S subunit, ATPase, 4" PSMC4 5704 NM_006503 /// NM_153001 /// XR_430205 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001824 // blastocyst development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201253_s_at NM_006319 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006319.1 /DEF=Homo sapiens CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) (CDIPT), mRNA. /FEA=mRNA /GEN=CDIPT /PROD=CDP-diacylglycerol--inositol3-phosphatidyltransferase (phosphatidylinositol synthase) /DB_XREF=gi:5453905 /UG=Hs.227107 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) /FL=gb:BC001444.1 gb:AF014807.1 gb:NM_006319.1" NM_006319 CDP-diacylglycerol--inositol 3-phosphatidyltransferase CDIPT 10423 NM_001286585 /// NM_001286586 /// NM_006319 /// NM_145752 /// XM_005255038 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046341 // CDP-diacylglycerol metabolic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay "0003881 // CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity // inferred from direct assay /// 0003881 // CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016780 // phosphotransferase activity, for other substituted phosphate groups // inferred from electronic annotation /// 0019992 // diacylglycerol binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043178 // alcohol binding // inferred from electronic annotation" 201254_x_at NM_001010 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001010.1 /DEF=Homo sapiens ribosomal protein S6 (RPS6), mRNA. /FEA=mRNA /GEN=RPS6 /PROD=ribosomal protein S6 /DB_XREF=gi:4506730 /UG=Hs.241507 ribosomal protein S6 /FL=gb:M20020.1 gb:NM_001010.1" NM_001010 ribosomal protein S6 RPS6 6194 NM_001010 "0000028 // ribosomal small subunit assembly // inferred from electronic annotation /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0031929 // TOR signaling // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030425 // dendrite // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0044297 // cell body // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201255_x_at NM_004639 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004639.1 /DEF=Homo sapiens HLA-B associated transcript-3 (D6S52E), mRNA. /FEA=mRNA /GEN=D6S52E /PROD=HLA-B associated transcript-3 /DB_XREF=gi:4758109 /UG=Hs.274348 HLA-B associated transcript-3 /FL=gb:M33519.1 gb:NM_004639.1" NM_004639 BCL2-associated athanogene 6 BAG6 7917 NM_001098534 /// NM_001199697 /// NM_001199698 /// NM_004639 /// NM_080702 /// NM_080703 /// XM_005249393 /// XM_005249396 /// XM_005272880 /// XM_005272883 /// XM_005275034 /// XM_005275037 /// XM_005275169 /// XM_005275172 /// XM_005275292 /// XM_005275295 /// XM_005275464 /// XM_005275468 /// XM_005275597 /// XM_005275601 /// XM_006715192 /// XM_006715193 /// XM_006715194 /// XM_006715195 /// XM_006715196 /// XM_006715197 /// XM_006715198 /// XM_006715199 /// XM_006715200 /// XM_006715201 /// XM_006715202 /// XM_006715203 /// XM_006725509 /// XM_006725510 /// XM_006725511 /// XM_006725512 /// XM_006725513 /// XM_006725514 /// XM_006725515 /// XM_006725516 /// XM_006725517 /// XM_006725518 /// XM_006725519 /// XM_006725520 /// XM_006725725 /// XM_006725726 /// XM_006725727 /// XM_006725728 /// XM_006725729 /// XM_006725730 /// XM_006725731 /// XM_006725732 /// XM_006725733 /// XM_006725734 /// XM_006725735 /// XM_006725736 /// XM_006725835 /// XM_006725836 /// XM_006725837 /// XM_006725838 /// XM_006725839 /// XM_006725840 /// XM_006725841 /// XM_006725842 /// XM_006725843 /// XM_006725844 /// XM_006725845 /// XM_006725846 /// XM_006725923 /// XM_006725924 /// XM_006725925 /// XM_006725926 /// XM_006725927 /// XM_006725928 /// XM_006725929 /// XM_006725930 /// XM_006725931 /// XM_006725932 /// XM_006725933 /// XM_006725934 /// XM_006726025 /// XM_006726026 /// XM_006726027 /// XM_006726028 /// XM_006726029 /// XM_006726030 /// XM_006726031 /// XM_006726032 /// XM_006726033 /// XM_006726034 /// XM_006726035 /// XM_006726036 /// XM_006726113 /// XM_006726114 /// XM_006726115 /// XM_006726116 /// XM_006726117 /// XM_006726118 /// XM_006726119 /// XM_006726120 /// XM_006726121 /// XM_006726122 /// XM_006726123 /// XM_006726124 0001822 // kidney development // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from sequence or structural similarity /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0071818 // BAT3 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from sequence or structural similarity /// 0043022 // ribosome binding // inferred from direct assay /// 0070628 // proteasome binding // inferred from sequence or structural similarity 201256_at NM_004718 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004718.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), mRNA. /FEA=mRNA /GEN=COX7A2L /PROD=cytochrome c oxidase subunit VIIa polypeptide 2like /DB_XREF=gi:4758041 /UG=Hs.30888 cytochrome c oxidase subunit VIIa polypeptide 2 like /FL=gb:BC005251.1 gb:AB007618.1 gb:NM_004718.1" NM_004718 cytochrome c oxidase subunit VIIa polypeptide 2 like COX7A2L 9167 NM_004718 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 201257_x_at NM_001006 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001006.1 /DEF=Homo sapiens ribosomal protein S3A (RPS3A), mRNA. /FEA=mRNA /GEN=RPS3A /PROD=ribosomal protein S3A /DB_XREF=gi:4506722 /UG=Hs.77039 ribosomal protein S3A /FL=gb:BC000204.1 gb:BC001708.1 gb:BC004981.1 gb:M84711.1 gb:M77234.1 gb:L13802.1 gb:NM_001006.1" NM_001006 "ribosomal protein S3A /// small nucleolar RNA, C/D box 73A" RPS3A /// SNORD73A 6189 /// 8944 NM_001006 /// NM_001267699 /// NR_000007 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0002181 // cytoplasmic translation // not recorded /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201258_at NM_001020 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001020.1 /DEF=Homo sapiens ribosomal protein S16 (RPS16), mRNA. /FEA=mRNA /GEN=RPS16 /PROD=ribosomal protein S16 /DB_XREF=gi:4506690 /UG=Hs.80617 ribosomal protein S16 /FL=gb:BC004324.1 gb:M60854.1 gb:NM_001020.1" NM_001020 ribosomal protein S16 RPS16 6217 NM_001020 /// XM_005259137 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201259_s_at AI768845 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI768845 /FEA=EST /DB_XREF=gi:5235354 /DB_XREF=est:wj12e10.x1 /CLONE=IMAGE:2402634 /UG=Hs.80919 synaptophysin-like protein /FL=gb:NM_006754.1 AI768845 synaptophysin-like 1 SYPL1 6856 NM_006754 /// NM_182715 /// XM_006716099 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // not recorded /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation 201260_s_at NM_006754 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006754.1 /DEF=Homo sapiens synaptophysin-like protein (SYPL), mRNA. /FEA=mRNA /GEN=SYPL /PROD=synaptophysin-like protein /DB_XREF=gi:5803184 /UG=Hs.80919 synaptophysin-like protein /FL=gb:NM_006754.1" NM_006754 synaptophysin-like 1 SYPL1 6856 NM_006754 /// NM_182715 /// XM_006716099 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // not recorded /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation 201261_x_at BC002416 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002416.1 /DEF=Homo sapiens, biglycan, clone MGC:2298, mRNA, complete cds. /FEA=mRNA /PROD=biglycan /DB_XREF=gi:12803216 /UG=Hs.821 biglycan /FL=gb:BC002416.1 gb:BC004244.1 gb:J04599.1 gb:NM_001711.1" BC002416 biglycan BGN 633 NM_001711 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201262_s_at NM_001711 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001711.1 /DEF=Homo sapiens biglycan (BGN), mRNA. /FEA=mRNA /GEN=BGN /PROD=biglycan /DB_XREF=gi:4502402 /UG=Hs.821 biglycan /FL=gb:BC002416.1 gb:BC004244.1 gb:J04599.1 gb:NM_001711.1" NM_001711 biglycan BGN 633 NM_001711 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201263_at NM_003191 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003191.1 /DEF=Homo sapiens threonyl-tRNA synthetase (TARS), mRNA. /FEA=mRNA /GEN=TARS /PROD=threonyl-tRNA synthetase /DB_XREF=gi:4507366 /UG=Hs.84131 threonyl-tRNA synthetase /FL=gb:BC000517.1 gb:M63180.1 gb:NM_003191.1" NM_003191 threonyl-tRNA synthetase TARS 6897 NM_001258437 /// NM_001258438 /// NM_152295 /// NR_047676 /// NR_047677 /// NR_047678 0006412 // translation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006435 // threonyl-tRNA aminoacylation // non-traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004829 // threonine-tRNA ligase activity // non-traceable author statement /// 0004829 // threonine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement" 201264_at NM_007263 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007263.1 /DEF=Homo sapiens coatomer protein complex, subunit epsilon (COPE), mRNA. /FEA=mRNA /GEN=COPE /PROD=coatomer protein complex, subunit epsilon /DB_XREF=gi:6005734 /UG=Hs.10326 coatomer protein complex, subunit epsilon /FL=gb:AL136928.1 gb:BC003155.1 gb:NM_007263.1" NM_007263 "coatomer protein complex, subunit epsilon" COPE 11316 NM_007263 /// NM_199442 /// NM_199444 "0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation 201265_at AF119897 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF119897.1 /DEF=Homo sapiens PRO2760 mRNA, complete cds. /FEA=mRNA /PROD=PRO2760 /DB_XREF=gi:7770230 /UG=Hs.111334 ferritin, light polypeptide /FL=gb:BC004245.1 gb:M11147.1 gb:M10119.1 gb:NM_000146.1 gb:AF119897.1" AF119897 201266_at NM_003330 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003330.1 /DEF=Homo sapiens thioredoxin reductase 1 (TXNRD1), mRNA. /FEA=mRNA /GEN=TXNRD1 /PROD=thioredoxin reductase 1 /DB_XREF=gi:4507746 /UG=Hs.13046 thioredoxin reductase 1 /FL=gb:D88687.1 gb:AF077367.1 gb:NM_003330.1 gb:AF208018.1" NM_003330 thioredoxin reductase 1 TXNRD1 7296 NM_001093771 /// NM_001261445 /// NM_001261446 /// NM_003330 /// NM_182729 /// NM_182742 /// NM_182743 0001707 // mesoderm formation // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006790 // sulfur compound metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016259 // selenocysteine metabolic process // inferred from electronic annotation /// 0042191 // methylmercury metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042537 // benzene-containing compound metabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070276 // halogen metabolic process // inferred from electronic annotation /// 0070995 // NADPH oxidation // inferred from electronic annotation /// 0071280 // cellular response to copper ion // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation "0004791 // thioredoxin-disulfide reductase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016174 // NAD(P)H oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016668 // oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor // inferred from electronic annotation /// 0033797 // selenate reductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0045340 // mercury ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation" 201267_s_at AL545523 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL545523 /FEA=EST /DB_XREF=gi:12878005 /DB_XREF=est:AL545523 /CLONE=CS0DI015YE19 (5 prime) /UG=Hs.250758 proteasome (prosome, macropain) 26S subunit, ATPase, 3 /FL=gb:M34079.1 gb:NM_002804.1" AL545523 "proteasome (prosome, macropain) 26S subunit, ATPase, 3" PSMC3 5702 NM_002804 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001824 // blastocyst development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201268_at NM_002512 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002512.1 /DEF=Homo sapiens non-metastatic cells 2, protein (NM23B) expressed in (NME2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NME2 /PROD=non-metastatic cells 2, protein (NM23B)expressed in /DB_XREF=gi:4505408 /UG=Hs.275163 non-metastatic cells 2, protein (NM23B) expressed in /FL=gb:BC002476.1 gb:M36981.1 gb:L16785.1 gb:NM_002512.1" NM_002512 NME1-NME2 readthrough /// NME/NM23 nucleoside diphosphate kinase 2 NME1-NME2 /// NME2 4831 /// 654364 NM_001018136 /// NM_001018137 /// NM_001018138 /// NM_001018139 /// NM_001198682 /// NM_002512 /// NR_037149 "0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006308 // DNA catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018106 // peptidyl-histidine phosphorylation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045682 // regulation of epidermis development // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation" 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004536 // deoxyribonuclease activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0004673 // protein histidine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation /// 0043024 // ribosomal small subunit binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201269_s_at AB028991 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB028991.1 /DEF=Homo sapiens mRNA for KIAA1068 protein, partial cds. /FEA=mRNA /GEN=KIAA1068 /PROD=KIAA1068 protein /DB_XREF=gi:5689472 /UG=Hs.4770 KIAA1068 protein /FL=gb:BC003691.1 gb:NM_015332.1" AB028991 NudC domain containing 3 NUDCD3 23386 NM_015332 201270_x_at NM_015332 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015332.1 /DEF=Homo sapiens KIAA1068 protein (KIAA1068), mRNA. /FEA=mRNA /GEN=KIAA1068 /PROD=KIAA1068 protein /DB_XREF=gi:13357209 /UG=Hs.4770 KIAA1068 protein /FL=gb:BC003691.1 gb:NM_015332.1" NM_015332 NudC domain containing 3 NUDCD3 23386 NM_015332 201271_s_at NM_016732 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016732.1 /DEF=Homo sapiens RNA-binding protein (autoantigenic) (RALY), transcript variant 1, mRNA. /FEA=mRNA /GEN=RALY /PROD=RNA-binding protein (autoantigenic) longisoform /DB_XREF=gi:8051630 /UG=Hs.74111 RNA-binding protein (autoantigenic) /FL=gb:AF148457.1 gb:NM_016732.1" NM_016732 RALY heterogeneous nuclear ribonucleoprotein RALY 22913 NM_007367 /// NM_016732 /// XM_005260334 /// XM_005260336 /// XM_006723742 /// XM_006723743 /// XM_006723744 /// XM_006723745 /// XM_006723746 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201272_at NM_001628 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001628.1 /DEF=Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), mRNA. /FEA=mRNA /GEN=AKR1B1 /PROD=aldo-keto reductase family 1, member B1 (aldosereductase) /DB_XREF=gi:4502048 /UG=Hs.75313 aldo-keto reductase family 1, member B1 (aldose reductase) /FL=gb:BC000260.1 gb:BC005387.1 gb:J04795.1 gb:J05017.1 gb:J05474.1 gb:M34720.1 gb:NM_001628.1" NM_001628 "aldo-keto reductase family 1, member B1 (aldose reductase)" AKR1B1 231 NM_001628 /// XM_005250234 0005975 // carbohydrate metabolic process // traceable author statement /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from electronic annotation /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043795 // glyceraldehyde oxidoreductase activity // inferred from direct assay 201273_s_at NM_003133 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003133.1 /DEF=Homo sapiens signal recognition particle 9kD (SRP9), mRNA. /FEA=mRNA /GEN=SRP9 /PROD=signal recognition particle 9kD /DB_XREF=gi:4507216 /UG=Hs.75975 signal recognition particle 9kD /FL=gb:NM_003133.1 gb:U20998.1" NM_003133 signal recognition particle 9kDa SRP9 6726 NM_001130440 /// NM_003133 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045900 // negative regulation of translational elongation // inferred from electronic annotation "0005737 // cytoplasm // inferred from electronic annotation /// 0005785 // signal recognition particle receptor complex // traceable author statement /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0003723 // RNA binding // traceable author statement /// 0005047 // signal recognition particle binding // traceable author statement /// 0008312 // 7S RNA binding // inferred from electronic annotation 201274_at NM_002790 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002790.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 5 (PSMA5), mRNA. /FEA=mRNA /GEN=PSMA5 /PROD=proteasome (prosome, macropain) subunit, alphatype, 5 /DB_XREF=gi:4506186 /UG=Hs.76913 proteasome (prosome, macropain) subunit, alpha type, 5 /FL=gb:NM_002790.1" NM_002790 "proteasome (prosome, macropain) subunit, alpha type, 5" PSMA5 5686 NM_001199772 /// NM_001199773 /// NM_001199774 /// NM_002790 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" "0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201275_at NM_002004 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002004.1 /DEF=Homo sapiens farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) (FDPS), mRNA. /FEA=mRNA /GEN=FDPS /PROD=farnesyl diphosphate synthase (farnesylpyrophosphate synthetase, dimethylallyltranstransferase,geranyltranstransferase) /DB_XREF=gi:4503684 /UG=Hs.77393 farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) /FL=gb:J05262.1 gb:D14697.1 gb:NM_002004.1" NM_002004 farnesyl diphosphate synthase FDPS 2224 NM_001135821 /// NM_001135822 /// NM_001242824 /// NM_001242825 /// NM_002004 /// XM_005244962 /// XM_005244963 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033384 // geranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045337 // farnesyl diphosphate biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0004337 // geranyltranstransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201276_at AF267863 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF267863.1 /DEF=Homo sapiens DC43 mRNA, complete cds. /FEA=mRNA /PROD=DC43 /DB_XREF=gi:12006052 /UG=Hs.77690 RAB5B, member RAS oncogene family /FL=gb:AF267863.1 gb:NM_002868.1" AF267863 "RAB5B, member RAS oncogene family" RAB5B 5869 NM_001252036 /// NM_001252037 /// NM_002868 /// XM_005269051 /// XM_005269052 /// XM_006719540 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0030742 // GTP-dependent protein binding // inferred from direct assay 201277_s_at NM_004499 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004499.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein AB (HNRPAB), mRNA. /FEA=mRNA /GEN=HNRPAB /PROD=heterogeneous nuclear ribonucleoprotein AB /DB_XREF=gi:4758541 /UG=Hs.81361 heterogeneous nuclear ribonucleoprotein AB /FL=gb:BC002625.1 gb:BC004561.1 gb:M65028.1 gb:NM_004499.1" NM_004499 heterogeneous nuclear ribonucleoprotein A/B HNRNPAB 3182 NM_004499 /// NM_031266 "0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201278_at N21202 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N21202 /FEA=EST /DB_XREF=gi:1126372 /DB_XREF=est:yx41e12.s1 /CLONE=IMAGE:264334 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1 N21202 "Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) /// uncharacterized LOC101926921" DAB2 /// LOC101926921 1601 /// 101926921 NM_001244871 /// NM_001343 /// XR_241759 /// XR_249766 /// XR_251775 "0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from mutant phenotype /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from mutant phenotype /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from mutant phenotype /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype /// 0038024 // cargo receptor activity // inferred from mutant phenotype /// 0046332 // SMAD binding // inferred from direct assay" 201279_s_at BC003064 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003064.1 /DEF=Homo sapiens, disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein), clone MGC:1764, mRNA, complete cds. /FEA=mRNA /PROD=disabled (Drosophila) homolog 2(mitogen-responsive phosphoprotein) /DB_XREF=gi:13111753 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1" BC003064 "Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) /// uncharacterized LOC101926921" DAB2 /// LOC101926921 1601 /// 101926921 NM_001244871 /// NM_001343 /// XR_241759 /// XR_249766 /// XR_251775 "0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from mutant phenotype /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from mutant phenotype /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from mutant phenotype /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype /// 0038024 // cargo receptor activity // inferred from mutant phenotype /// 0046332 // SMAD binding // inferred from direct assay" 201280_s_at NM_001343 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001343.1 /DEF=Homo sapiens disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) (DAB2), mRNA. /FEA=mRNA /GEN=DAB2 /PROD=disabled (Drosophila) homolog 2 /DB_XREF=gi:4503250 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1" NM_001343 "Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) /// uncharacterized LOC101926921" DAB2 /// LOC101926921 1601 /// 101926921 NM_001244871 /// NM_001343 /// XR_241759 /// XR_249766 /// XR_251775 "0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from mutant phenotype /// 2000370 // positive regulation of clathrin-mediated endocytosis // inferred from mutant phenotype /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from mutant phenotype /// 2001046 // positive regulation of integrin-mediated signaling pathway // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0035612 // AP-2 adaptor complex binding // inferred from electronic annotation /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype /// 0038024 // cargo receptor activity // inferred from mutant phenotype /// 0046332 // SMAD binding // inferred from direct assay" 201281_at NM_007002 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007002.1 /DEF=Homo sapiens cell membrane glycoprotein, 110000M(r) (surface antigen) (GP110), mRNA. /FEA=mRNA /GEN=GP110 /PROD=cell membrane glycoprotein, 110000M(r) (surfaceantigen) /DB_XREF=gi:5901959 /UG=Hs.90107 cell membrane glycoprotein, 110000M(r) (surface antigen) /FL=gb:NM_007002.1 gb:D64154.1" NM_007002 adhesion regulating molecule 1 ADRM1 11047 NM_001281437 /// NM_001281438 /// NM_007002 /// NM_175573 /// XM_005260257 0006368 // transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0010950 // positive regulation of endopeptidase activity // inferred from direct assay /// 0043248 // proteasome assembly // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0061133 // endopeptidase activator activity // inferred from direct assay /// 0070628 // proteasome binding // inferred from direct assay 201282_at NM_002541 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002541.1 /DEF=Homo sapiens oxoglutarate dehydrogenase (lipoamide) (OGDH), mRNA. /FEA=mRNA /GEN=OGDH /PROD=oxoglutarate dehydrogenase (lipoamide) /DB_XREF=gi:4505492 /UG=Hs.168669 oxoglutarate dehydrogenase (lipoamide) /FL=gb:BC004964.1 gb:NM_002541.1 gb:D10523.1" NM_002541 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) OGDH 4967 NM_001003941 /// NM_001165036 /// NM_002541 /// XM_005249759 /// XM_005249761 0006091 // generation of precursor metabolites and energy // inferred from sequence or structural similarity /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006103 // 2-oxoglutarate metabolic process // inferred from electronic annotation /// 0006104 // succinyl-CoA metabolic process // inferred from electronic annotation /// 0006554 // lysine catabolic process // traceable author statement /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0021860 // pyramidal neuron development // inferred from electronic annotation /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061034 // olfactory bulb mitral cell layer development // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity /// 0045252 // oxoglutarate dehydrogenase complex // inferred from electronic annotation "0004591 // oxoglutarate dehydrogenase (succinyl-transferring) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0034602 // oxoglutarate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation" 201283_s_at J03068 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J03068.1 /DEF=Human DNF1552 (lung) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181629 /UG=Hs.78223 N-acylaminoacyl-peptide hydrolase /FL=gb:BC000362.1 gb:BC001826.1 gb:J03068.1 gb:D38441.1 gb:AF141383.1 gb:NM_001640.2" J03068 "trafficking protein, kinesin binding 1" TRAK1 22906 NM_001042646 /// NM_001265608 /// NM_001265609 /// NM_001265610 /// NM_014965 /// XM_005264956 /// XM_005264957 /// XM_005264958 /// XM_005264959 /// XM_005264960 /// XM_005264962 /// XM_005264963 /// XM_005264964 /// XM_006713028 /// XM_006713029 /// XM_006713030 /// XM_006713031 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0050435 // beta-amyloid metabolic process // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from electronic annotation 201284_s_at NM_001640 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001640.2 /DEF=Homo sapiens N-acylaminoacyl-peptide hydrolase (APEH), mRNA. /FEA=mRNA /GEN=APEH /PROD=N-acylaminoacyl-peptide hydrolase /DB_XREF=gi:9951916 /UG=Hs.78223 N-acylaminoacyl-peptide hydrolase /FL=gb:BC000362.1 gb:BC001826.1 gb:J03068.1 gb:D38441.1 gb:AF141383.1 gb:NM_001640.2" NM_001640 acylaminoacyl-peptide hydrolase APEH 327 NM_001640 /// XM_005265097 /// XM_005265098 0006508 // proteolysis // inferred from direct assay /// 0050435 // beta-amyloid metabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201285_at NM_013446 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013446.1 /DEF=Homo sapiens makorin, ring finger protein, 1 (MKRN1), mRNA. /FEA=mRNA /GEN=MKRN1 /PROD=makorin, ring finger protein, 1 /DB_XREF=gi:7305272 /UG=Hs.7838 makorin, ring finger protein, 1 /FL=gb:AL136812.1 gb:AF192784.1 gb:NM_013446.1" NM_013446 makorin ring finger protein 1 MKRN1 23608 NM_001145125 /// NM_001291663 /// NM_013446 /// NR_117084 0000209 // protein polyubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201286_at Z48199 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:Z48199 /DEF=H.sapiens syndecan-1 gene (exons 2-5) /FEA=mRNA /DB_XREF=gi:666051 /UG=Hs.82109 syndecan 1 /FL=gb:J05392.1 gb:NM_002997.1 Z48199 syndecan 1 SDC1 6382 NM_001006946 /// NM_002997 /// XM_005262620 /// XM_005262621 /// XM_005262622 /// XM_006712060 "0001523 // retinoid metabolic process // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048627 // myoblast development // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0055002 // striated muscle cell development // inferred from expression pattern /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201287_s_at NM_002997 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002997.1 /DEF=Homo sapiens syndecan 1 (SDC1), mRNA. /FEA=mRNA /GEN=SDC1 /PROD=syndecan 1 /DB_XREF=gi:4506858 /UG=Hs.82109 syndecan 1 /FL=gb:J05392.1 gb:NM_002997.1" NM_002997 syndecan 1 SDC1 6382 NM_001006946 /// NM_002997 /// XM_005262620 /// XM_005262621 /// XM_005262622 /// XM_006712060 "0001523 // retinoid metabolic process // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048627 // myoblast development // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0055002 // striated muscle cell development // inferred from expression pattern /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201288_at NM_001175 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001175.1 /DEF=Homo sapiens Rho GDP dissociation inhibitor (GDI) beta (ARHGDIB), mRNA. /FEA=mRNA /GEN=ARHGDIB /PROD=Rho GDP dissociation inhibitor (GDI) beta /DB_XREF=gi:10835001 /UG=Hs.83656 Rho GDP dissociation inhibitor (GDI) beta /FL=gb:NM_001175.1 gb:L20688.1" NM_001175 Rho GDP dissociation inhibitor (GDI) beta ARHGDIB 397 NM_001175 0006928 // cellular component movement // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation 201289_at NM_001554 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001554.1 /DEF=Homo sapiens cysteine-rich, angiogenic inducer, 61 (CYR61), mRNA. /FEA=mRNA /GEN=CYR61 /PROD=cysteine-rich, angiogenic inducer, 61 /DB_XREF=gi:4504612 /UG=Hs.8867 cysteine-rich, angiogenic inducer, 61 /FL=gb:BC001271.1 gb:U62015.1 gb:AF003594.1 gb:AF031385.1 gb:NM_001554.1" NM_001554 "cysteine-rich, angiogenic inducer, 61" CYR61 3491 NM_001554 "0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002041 // intussusceptive angiogenesis // inferred from electronic annotation /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003278 // apoptotic process involved in heart morphogenesis // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from genetic interaction /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201290_at NM_014300 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014300.1 /DEF=Homo sapiens signal peptidase complex (18kD) (SPC18), mRNA. /FEA=mRNA /GEN=SPC18 /PROD=signal peptidase complex (18kD) /DB_XREF=gi:7657608 /UG=Hs.9534 signal peptidase complex (18kD) /FL=gb:BC000359.1 gb:AF061737.1 gb:AF108945.1 gb:NM_014300.1" NM_014300 SEC11 homolog A (S. cerevisiae) SEC11A 23478 NM_001271918 /// NM_001271919 /// NM_001271920 /// NM_001271921 /// NM_001271922 /// NM_014300 /// NR_073518 0006412 // translation // traceable author statement /// 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201291_s_at AU159942 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU159942 /FEA=EST /DB_XREF=gi:11021463 /DB_XREF=est:AU159942 /CLONE=Y79AA1000724 /UG=Hs.156346 topoisomerase (DNA) II alpha (170kD) /FL=gb:J04088.1 gb:NM_001067.1 AU159942 topoisomerase (DNA) II alpha 170kDa TOP2A 7153 NM_001067 /// XM_005257632 0000278 // mitotic cell cycle // traceable author statement /// 0000712 // resolution of meiotic recombination intermediates // not recorded /// 0000819 // sister chromatid segregation // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // /// 0006265 // DNA topological change // inferred from direct assay /// 0006266 // DNA ligation // inferred from direct assay /// 0006268 // DNA unwinding involved in DNA replication // not recorded /// 0006281 // DNA repair // non-traceable author statement /// 0006312 // mitotic recombination // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044774 // mitotic DNA integrity checkpoint // not recorded /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045870 // positive regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0009295 // nucleoid // not recorded /// 0009330 // DNA topoisomerase complex (ATP-hydrolyzing) // inferred from direct assay /// 0019035 // viral integration complex // non-traceable author statement /// 0043234 // protein complex // inferred from physical interaction "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003918 // DNA topoisomerase type II (ATP-hydrolyzing) activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction" 201292_at AL561834 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL561834 /FEA=EST /DB_XREF=gi:12909658 /DB_XREF=est:AL561834 /CLONE=CS0DB005YC15 (3 prime) /UG=Hs.156346 topoisomerase (DNA) II alpha (170kD) /FL=gb:J04088.1 gb:NM_001067.1 AL561834 topoisomerase (DNA) II alpha 170kDa TOP2A 7153 NM_001067 /// XM_005257632 0000278 // mitotic cell cycle // traceable author statement /// 0000712 // resolution of meiotic recombination intermediates // not recorded /// 0000819 // sister chromatid segregation // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006261 // DNA-dependent DNA replication // /// 0006265 // DNA topological change // inferred from direct assay /// 0006266 // DNA ligation // inferred from direct assay /// 0006268 // DNA unwinding involved in DNA replication // not recorded /// 0006281 // DNA repair // non-traceable author statement /// 0006312 // mitotic recombination // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0044774 // mitotic DNA integrity checkpoint // not recorded /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045870 // positive regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0009295 // nucleoid // not recorded /// 0009330 // DNA topoisomerase complex (ATP-hydrolyzing) // inferred from direct assay /// 0019035 // viral integration complex // non-traceable author statement /// 0043234 // protein complex // inferred from physical interaction "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003918 // DNA topoisomerase type II (ATP-hydrolyzing) activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction" 201293_x_at NM_021130 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021130.1 /DEF=Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), mRNA. /FEA=mRNA /GEN=PPIA /PROD=peptidylprolyl isomerase A (cyclophilin A) /DB_XREF=gi:10863926 /UG=Hs.182937 peptidylprolyl isomerase A (cyclophilin A) /FL=gb:NM_021130.1 gb:BC000689.1 gb:BC005320.1" NM_021130 peptidyl-prolyl cis-trans isomerase A-like /// peptidylprolyl isomerase A (cyclophilin A) LOC101060363 /// PPIA 5478 /// 101060363 NM_021130 /// NM_203430 /// NM_203431 /// XM_003960117 /// XM_005246048 /// XM_005249791 /// XM_005275876 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006278 // RNA-dependent DNA replication // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019061 // uncoating of virus // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019076 // viral release from host cell // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030260 // entry into host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0075713 // establishment of integrated proviral latency // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 201294_s_at N24643 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N24643 /FEA=EST /DB_XREF=gi:1138793 /DB_XREF=est:yx89f11.s1 /CLONE=IMAGE:268941 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 N24643 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201295_s_at BF111821 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF111821 /FEA=EST /DB_XREF=gi:10941511 /DB_XREF=est:7l36a06.x1 /CLONE=IMAGE:3523474 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 BF111821 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201296_s_at NM_015626 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015626.1 /DEF=Homo sapiens DKFZP564A122 protein (DKFZP564A122), mRNA. /FEA=mRNA /GEN=DKFZP564A122 /PROD=DKFZP564A122 protein /DB_XREF=gi:7661595 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1" NM_015626 WD repeat and SOCS box containing 1 WSB1 26118 NM_015626 /// NM_134264 /// NM_134265 /// XM_005257963 /// XR_243778 /// XR_429881 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201297_s_at AK023321 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK023321.1 /DEF=Homo sapiens cDNA FLJ13259 fis, clone OVARC1000876, moderately similar to MOB1 PROTEIN. /FEA=mRNA /DB_XREF=gi:10435206 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1" AK023321 MOB kinase activator 1A MOB1A 55233 NM_018221 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201298_s_at BC003398 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003398.1 /DEF=Homo sapiens, hypothetical protein FLJ10788, clone MGC:4929, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10788 /DB_XREF=gi:13097287 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1" BC003398 MOB kinase activator 1A MOB1A 55233 NM_018221 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201299_s_at NM_018221 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018221.1 /DEF=Homo sapiens hypothetical protein FLJ10788 (FLJ10788), mRNA. /FEA=mRNA /GEN=FLJ10788 /PROD=hypothetical protein FLJ10788 /DB_XREF=gi:8922670 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1" NM_018221 MOB kinase activator 1A MOB1A 55233 NM_018221 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201300_s_at NM_000311 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000311.1 /DEF=Homo sapiens prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) (PRNP), mRNA. /FEA=mRNA /GEN=PRNP /PROD=prion protein /DB_XREF=gi:4506112 /UG=Hs.74621 prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) /FL=gb:AY008282.1 gb:M13899.1 gb:NM_000311.1" NM_000311 prion protein PRNP 5621 NM_000311 /// NM_001080121 /// NM_001080122 /// NM_001080123 /// NM_001271561 /// NM_183079 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0006878 // cellular copper ion homeostasis // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0032689 // negative regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032700 // negative regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032703 // negative regulation of interleukin-2 production // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0046007 // negative regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0070885 // negative regulation of calcineurin-NFAT signaling cascade // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005507 // copper ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043008 // ATP-dependent protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from electronic annotation 201301_s_at BC000182 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000182.1 /DEF=Homo sapiens, annexin A4, clone MGC:2271, mRNA, complete cds. /FEA=mRNA /PROD=annexin A4 /DB_XREF=gi:12652858 /UG=Hs.77840 annexin A4 /FL=gb:D78152.1 gb:BC000182.1 gb:M82809.1 gb:M19383.1 gb:NM_001153.2" BC000182 annexin A4 ANXA4 307 NM_001153 /// XM_006712000 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // non-traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation /// 2000483 // negative regulation of interleukin-8 secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0012506 // vesicle membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 201302_at NM_001153 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001153.2 /DEF=Homo sapiens annexin A4 (ANXA4), mRNA. /FEA=mRNA /GEN=ANXA4 /PROD=annexin IV /DB_XREF=gi:4809272 /UG=Hs.77840 annexin A4 /FL=gb:D78152.1 gb:BC000182.1 gb:M82809.1 gb:M19383.1 gb:NM_001153.2" NM_001153 annexin A4 ANXA4 307 NM_001153 /// XM_006712000 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // non-traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation /// 2000483 // negative regulation of interleukin-8 secretion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0012506 // vesicle membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004859 // phospholipase inhibitor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 201303_at NM_014740 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014740.1 /DEF=Homo sapiens KIAA0111 gene product (KIAA0111), mRNA. /FEA=mRNA /GEN=KIAA0111 /PROD=KIAA0111 gene product /DB_XREF=gi:7661919 /UG=Hs.79768 KIAA0111 gene product /FL=gb:BC003662.1 gb:BC004386.1 gb:D21853.1 gb:NM_014740.1" NM_014740 eukaryotic translation initiation factor 4A3 EIF4A3 9775 NM_014740 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201304_at NM_005000 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005000.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13) (NDUFA5), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NDUFA5 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 5 /DB_XREF=gi:13699821 /UG=Hs.83916 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13) /FL=gb:BC000813.1 gb:NM_005000.2 gb:U53468.1 gb:U64028.1" NM_005000 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5" NDUFA5 4698 NM_001282419 /// NM_001282420 /// NM_001282421 /// NM_001282422 /// NM_001291304 /// NM_005000 /// NR_104168 /// NR_104169 /// NR_111925 /// NR_111926 /// XM_005250371 /// XR_426239 /// XR_428243 /// XR_432226 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation "0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation" 201305_x_at AV712577 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV712577 /FEA=EST /DB_XREF=gi:10731883 /DB_XREF=est:AV712577 /CLONE=DCAAUH03 /UG=Hs.84264 acidic protein rich in leucines /FL=gb:U70439.1 gb:NM_006401.1 AV712577 "acidic (leucine-rich) nuclear phosphoprotein 32 family, member B" ANP32B 10541 NM_006401 0006334 // nucleosome assembly // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042393 // histone binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from direct assay 201306_s_at NM_006401 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006401.1 /DEF=Homo sapiens acidic protein rich in leucines (SSP29), mRNA. /FEA=mRNA /GEN=SSP29 /PROD=acidic protein rich in leucines /DB_XREF=gi:5454087 /UG=Hs.84264 acidic protein rich in leucines /FL=gb:U70439.1 gb:NM_006401.1" NM_006401 "acidic (leucine-rich) nuclear phosphoprotein 32 family, member B" ANP32B 10541 NM_006401 0006334 // nucleosome assembly // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045596 // negative regulation of cell differentiation // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0042393 // histone binding // inferred from direct assay /// 0070063 // RNA polymerase binding // inferred from direct assay 201307_at AL534972 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL534972 /FEA=EST /DB_XREF=gi:12798465 /DB_XREF=est:AL534972 /CLONE=CS0DF007YI02 (5 prime) /UG=Hs.8768 hypothetical protein FLJ10849 /FL=gb:NM_018243.1 AL534972 septin 11 SEPT11 55752 NM_018243 /// XM_005263120 /// XM_005263121 /// XM_005263122 /// XM_006714259 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201308_s_at NM_018243 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018243.1 /DEF=Homo sapiens hypothetical protein FLJ10849 (FLJ10849), mRNA. /FEA=mRNA /GEN=FLJ10849 /PROD=hypothetical protein FLJ10849 /DB_XREF=gi:8922711 /UG=Hs.8768 hypothetical protein FLJ10849 /FL=gb:NM_018243.1" NM_018243 septin 11 SEPT11 55752 NM_018243 /// XM_005263120 /// XM_005263121 /// XM_005263122 /// XM_006714259 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031105 // septin complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201309_x_at U36189 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U36189.1 /DEF=Human p311 protein (hP311) mRNA, complete cds. /FEA=mRNA /GEN=hP311 /PROD=p311 protein /DB_XREF=gi:1244509 /UG=Hs.142827 P311 protein /FL=gb:U36189.1 gb:NM_004772.1 gb:U30521.1" U36189 neuronal regeneration related protein NREP 9315 NM_001142474 /// NM_001142475 /// NM_001142476 /// NM_001142477 /// NM_001142478 /// NM_001142479 /// NM_001142480 /// NM_001142481 /// NM_001142482 /// NM_001142483 /// NM_004772 /// XM_006714732 /// XM_006714733 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201310_s_at NM_004772 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004772.1 /DEF=Homo sapiens P311 protein (P311), mRNA. /FEA=mRNA /GEN=P311 /PROD=P311 protein /DB_XREF=gi:4758865 /UG=Hs.142827 P311 protein /FL=gb:U36189.1 gb:NM_004772.1 gb:U30521.1" NM_004772 neuronal regeneration related protein NREP 9315 NM_001142474 /// NM_001142475 /// NM_001142476 /// NM_001142477 /// NM_001142478 /// NM_001142479 /// NM_001142480 /// NM_001142481 /// NM_001142482 /// NM_001142483 /// NM_004772 /// XM_006714732 /// XM_006714733 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201311_s_at AL515318 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL515318 /FEA=EST /DB_XREF=gi:12778811 /DB_XREF=est:AL515318 /CLONE=CL0BB030ZH05 (5 prime) /UG=Hs.14368 SH3 domain binding glutamic acid-rich protein like /FL=gb:AL136718.1 gb:AF042081.1 gb:NM_003022.1 AL515318 SH3 domain binding glutamate-rich protein like SH3BGRL 6451 NM_003022 0009967 // positive regulation of signal transduction // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 201312_s_at NM_003022 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003022.1 /DEF=Homo sapiens SH3 domain binding glutamic acid-rich protein like (SH3BGRL), mRNA. /FEA=mRNA /GEN=SH3BGRL /PROD=SH3 domain binding glutamic acid-rich proteinlike /DB_XREF=gi:4506924 /UG=Hs.14368 SH3 domain binding glutamic acid-rich protein like /FL=gb:AL136718.1 gb:AF042081.1 gb:NM_003022.1" NM_003022 SH3 domain binding glutamate-rich protein like SH3BGRL 6451 NM_003022 0009967 // positive regulation of signal transduction // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 201313_at NM_001975 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001975.1 /DEF=Homo sapiens enolase 2, (gamma, neuronal) (ENO2), mRNA. /FEA=mRNA /GEN=ENO2 /PROD=enolase 2, (gamma, neuronal) /DB_XREF=gi:5803010 /UG=Hs.146580 enolase 2, (gamma, neuronal) /FL=gb:BC002745.1 gb:NM_001975.1 gb:M22349.1" NM_001975 "enolase 2 (gamma, neuronal)" ENO2 2026 NM_001975 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0001917 // photoreceptor inner segment // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201314_at NM_006374 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006374.1 /DEF=Homo sapiens serinethreonine kinase 25 (Ste20, yeast homolog) (STK25), mRNA. /FEA=mRNA /GEN=STK25 /PROD=serinethreonine kinase 25 (Ste20, yeasthomolog) /DB_XREF=gi:5454173 /UG=Hs.155206 serinethreonine kinase 25 (Ste20, yeast homolog) /FL=gb:D63780.1 gb:NM_006374.1" NM_006374 serine/threonine kinase 25 STK25 10494 NM_001271977 /// NM_001271978 /// NM_001271979 /// NM_001271980 /// NM_001282305 /// NM_001282306 /// NM_001282307 /// NM_001282308 /// NM_006374 /// XM_006712197 /// XM_006712198 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // not recorded /// 0006979 // response to oxidative stress // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0045595 // regulation of cell differentiation // not recorded /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from direct assay 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 201315_x_at NM_006435 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006435.1 /DEF=Homo sapiens interferon induced transmembrane protein 2 (1-8D) (IFITM2), mRNA. /FEA=mRNA /GEN=IFITM2 /PROD=interferon induced transmembrane protein 2(1-8D) /DB_XREF=gi:10835237 /UG=Hs.174195 interferon induced transmembrane protein 2 (1-8D) /FL=gb:NM_006435.1" NM_006435 interferon induced transmembrane protein 2 IFITM2 10581 NM_006435 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0035456 // response to interferon-beta // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201316_at AL523904 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL523904 /FEA=EST /DB_XREF=gi:12787397 /DB_XREF=est:AL523904 /CLONE=CS0DC003YB07 (3 prime) /UG=Hs.181309 proteasome (prosome, macropain) subunit, alpha type, 2 /FL=gb:NM_002787.1" AL523904 "proteasome (prosome, macropain) subunit, alpha type, 2" PSMA2 5683 NM_002787 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" "0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201317_s_at NM_002787 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002787.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2), mRNA. /FEA=mRNA /GEN=PSMA2 /PROD=proteasome (prosome, macropain) subunit, alphatype, 2 /DB_XREF=gi:4506180 /UG=Hs.181309 proteasome (prosome, macropain) subunit, alpha type, 2 /FL=gb:NM_002787.1" NM_002787 "proteasome (prosome, macropain) subunit, alpha type, 2" PSMA2 5683 NM_002787 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" "0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201318_s_at NM_006471 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006471.1 /DEF=Homo sapiens myosin, light polypeptide, regulatory, non-sarcomeric (20kD) (MLCB), mRNA. /FEA=mRNA /GEN=MLCB /PROD=myosin, light polypeptide, regulatory,non-sarcomeric (20kD) /DB_XREF=gi:5453739 /UG=Hs.233936 myosin, light polypeptide, regulatory, non-sarcomeric (20kD) /FL=gb:NM_006471.1" NM_006471 "myosin, light chain 12A, regulatory, non-sarcomeric /// myosin, light chain 12B, regulatory" MYL12A /// MYL12B 10627 /// 103910 NM_001144944 /// NM_001144945 /// NM_001144946 /// NM_006471 /// NM_033546 /// XM_005258076 /// XM_005258077 /// XM_005258078 0006936 // muscle contraction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201319_at NM_006471 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006471.1 /DEF=Homo sapiens myosin, light polypeptide, regulatory, non-sarcomeric (20kD) (MLCB), mRNA. /FEA=mRNA /GEN=MLCB /PROD=myosin, light polypeptide, regulatory,non-sarcomeric (20kD) /DB_XREF=gi:5453739 /UG=Hs.233936 myosin, light polypeptide, regulatory, non-sarcomeric (20kD) /FL=gb:NM_006471.1" NM_006471 "myosin, light chain 12A, regulatory, non-sarcomeric" MYL12A 10627 NM_006471 /// XM_005258076 /// XM_005258077 /// XM_005258078 0008360 // regulation of cell shape // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0016460 // myosin II complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201320_at BF663402 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF663402 /FEA=EST /DB_XREF=gi:11937297 /DB_XREF=est:602144558F1 /CLONE=IMAGE:4297695 /UG=Hs.236030 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 /FL=gb:U66616.1 gb:NM_003075.1" BF663402 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2" SMARCC2 6601 NM_001130420 /// NM_003075 /// NM_139067 /// XM_005269101 /// XM_005269102 /// XM_005269103 /// XM_005269104 "0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 201321_s_at NM_003075 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003075.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 (SMARCC2), mRNA. /FEA=mRNA /GEN=SMARCC2 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily c, member 2 /DB_XREF=gi:4507080 /UG=Hs.236030 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 /FL=gb:U66616.1 gb:NM_003075.1" NM_003075 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2" SMARCC2 6601 NM_001130420 /// NM_003075 /// NM_139067 /// XM_005269101 /// XM_005269102 /// XM_005269103 /// XM_005269104 "0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016459 // myosin complex // traceable author statement /// 0016461 // unconventional myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003774 // motor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from sequence or structural similarity /// 0031492 // nucleosomal DNA binding // inferred from direct assay 201322_at NM_001686 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001686.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (ATP5B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ATP5B /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, beta polypeptide /DB_XREF=gi:4502294 /UG=Hs.25 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide /FL=gb:D00022.1 gb:NM_001686.1" NM_001686 "ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide" ATP5B 506 NM_001686 0001525 // angiogenesis // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006091 // generation of precursor metabolites and energy // non-traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051453 // regulation of intracellular pH // inferred from mutant phenotype "0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005754 // mitochondrial proton-transporting ATP synthase, catalytic core // non-traceable author statement /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred by curator /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from mutant phenotype" 201323_at NM_006824 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006824.1 /DEF=Homo sapiens nucleolar protein p40; homolog of yeast EBNA1-binding protein (P40), mRNA. /FEA=mRNA /GEN=P40 /PROD=nucleolar protein p40; homolog of yeastEBNA1-binding protein /DB_XREF=gi:5803110 /UG=Hs.74407 nucleolar protein p40; homolog of yeast EBNA1-binding protein /FL=gb:U86602.1 gb:NM_006824.1" NM_006824 EBNA1 binding protein 2 /// microRNA 6733 EBNA1BP2 /// MIR6733 10969 /// 102465439 NM_001159936 /// NM_006824 /// NR_106791 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 201324_at NM_001423 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001423.1 /DEF=Homo sapiens epithelial membrane protein 1 (EMP1), mRNA. /FEA=mRNA /GEN=EMP1 /PROD=epithelial membrane protein 1 /DB_XREF=gi:4503558 /UG=Hs.79368 epithelial membrane protein 1 /FL=gb:U77085.1 gb:U43916.1 gb:NM_001423.1" NM_001423 epithelial membrane protein 1 EMP1 2012 NM_001423 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 201325_s_at NM_001423 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001423.1 /DEF=Homo sapiens epithelial membrane protein 1 (EMP1), mRNA. /FEA=mRNA /GEN=EMP1 /PROD=epithelial membrane protein 1 /DB_XREF=gi:4503558 /UG=Hs.79368 epithelial membrane protein 1 /FL=gb:U77085.1 gb:U43916.1 gb:NM_001423.1" NM_001423 epithelial membrane protein 1 EMP1 2012 NM_001423 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 201326_at BE737030 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE737030 /FEA=EST /DB_XREF=gi:10151022 /DB_XREF=est:601304610F1 /CLONE=IMAGE:3639098 /UG=Hs.82916 chaperonin containing TCP1, subunit 6A (zeta 1) /FL=gb:M94083.1 gb:NM_001762.1 gb:L27706.1" BE737030 "chaperonin containing TCP1, subunit 6A (zeta 1)" CCT6A 908 NM_001009186 /// NM_001762 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 201327_s_at NM_001762 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001762.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 6A (zeta 1) (CCT6A), mRNA. /FEA=mRNA /GEN=CCT6A /PROD=chaperonin containing TCP1, subunit 6A (zeta 1) /DB_XREF=gi:4502642 /UG=Hs.82916 chaperonin containing TCP1, subunit 6A (zeta 1) /FL=gb:M94083.1 gb:NM_001762.1 gb:L27706.1" NM_001762 "chaperonin containing TCP1, subunit 6A (zeta 1)" CCT6A 908 NM_001009186 /// NM_001762 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 201328_at AL575509 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL575509 /FEA=EST /DB_XREF=gi:12936742 /DB_XREF=est:AL575509 /CLONE=CS0DI059YP21 (3 prime) /UG=Hs.85146 v-ets avian erythroblastosis virus E26 oncogene homolog 2 /FL=gb:J04102.1 gb:NM_005239.1 AL575509 v-ets avian erythroblastosis virus E26 oncogene homolog 2 ETS2 2114 NM_001256295 /// NM_005239 /// XM_005260935 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201329_s_at NM_005239 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005239.1 /DEF=Homo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog 2 (ETS2), mRNA. /FEA=mRNA /GEN=ETS2 /PROD=v-ets avian erythroblastosis virus E26 oncogenehomolog 2 /DB_XREF=gi:4885220 /UG=Hs.85146 v-ets avian erythroblastosis virus E26 oncogene homolog 2 /FL=gb:J04102.1 gb:NM_005239.1" NM_005239 v-ets avian erythroblastosis virus E26 oncogene homolog 2 ETS2 2114 NM_001256295 /// NM_005239 /// XM_005260935 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201330_at NM_002887 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002887.1 /DEF=Homo sapiens arginyl-tRNA synthetase (RARS), mRNA. /FEA=mRNA /GEN=RARS /PROD=arginyl-tRNA synthetase /DB_XREF=gi:4506428 /UG=Hs.180832 arginyl-tRNA synthetase /FL=gb:BC000528.1 gb:NM_002887.1" NM_002887 arginyl-tRNA synthetase RARS 5917 NM_002887 /// XM_005265957 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006420 // arginyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004814 // arginine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0034618 // arginine binding // inferred from electronic annotation 201331_s_at BC004973 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC004973.1 /DEF=Homo sapiens, signal transducer and activator of transcription 6, interleukin-4 induced, clone MGC:3649, mRNA, complete cds. /FEA=mRNA /PROD=signal transducer and activator of transcription6, interleukin-4 induced /DB_XREF=gi:13436385 /UG=Hs.181015 signal transducer and activator of transcription 6, interleukin-4 induced /FL=gb:BC004973.1 gb:NM_003153.1 gb:U16031.1" BC004973 "signal transducer and activator of transcription 6, interleukin-4 induced" STAT6 6778 NM_001178078 /// NM_001178079 /// NM_001178080 /// NM_001178081 /// NM_003153 /// NR_033659 /// XM_006719573 /// XM_006719574 /// XM_006719575 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002296 // T-helper 1 cell lineage commitment // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035771 // interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0060443 // mammary gland morphogenesis // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 1902170 // cellular response to reactive nitrogen species // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201332_s_at NM_003153 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003153.1 /DEF=Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), mRNA. /FEA=mRNA /GEN=STAT6 /PROD=signal transducer and activator of transcription6, interleukin-4 induced /DB_XREF=gi:4507258 /UG=Hs.181015 signal transducer and activator of transcription 6, interleukin-4 induced /FL=gb:BC004973.1 gb:NM_003153.1 gb:U16031.1" NM_003153 "signal transducer and activator of transcription 6, interleukin-4 induced" STAT6 6778 NM_001178078 /// NM_001178079 /// NM_001178080 /// NM_001178081 /// NM_003153 /// NR_033659 /// XM_006719573 /// XM_006719574 /// XM_006719575 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002296 // T-helper 1 cell lineage commitment // inferred from electronic annotation /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035771 // interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0060443 // mammary gland morphogenesis // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 1902170 // cellular response to reactive nitrogen species // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201333_s_at AI807672 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI807672 /FEA=EST /DB_XREF=gi:5394238 /DB_XREF=est:wf49f10.x1 /CLONE=IMAGE:2358955 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1 AI807672 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_001198665 /// NM_015313 /// XM_005271478 /// XM_005271480 /// XM_006718805 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 201334_s_at AB002380 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB002380.1 /DEF=Human mRNA for KIAA0382 gene, partial cds. /FEA=mRNA /GEN=KIAA0382 /DB_XREF=gi:2224704 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1" AB002380 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_001198665 /// NM_015313 /// XM_005271478 /// XM_005271480 /// XM_006718805 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 201335_s_at NM_015313 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015313.1 /DEF=Homo sapiens KIAA0382 protein; leukemia-associated rho guanine nucleotide exchange factor (GEF) (ARHGEF12), mRNA. /FEA=mRNA /GEN=ARHGEF12 /PROD=KIAA0382 protein; leukemia-associated rhoguanine nucleotide exchange factor (GEF) /DB_XREF=gi:7662087 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1" NM_015313 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_001198665 /// NM_015313 /// XM_005271478 /// XM_005271480 /// XM_006718805 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 201336_at BC003570 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003570.1 /DEF=Homo sapiens, Similar to vesicle-associated membrane protein 3, clone MGC:2110, mRNA, complete cds. /FEA=mRNA /PROD=Similar to vesicle-associated membrane protein3 /DB_XREF=gi:13097737 /UG=Hs.66708 vesicle-associated membrane protein 3 (cellubrevin) /FL=gb:BC003570.1 gb:NM_004781.2" BC003570 vesicle-associated membrane protein 3 VAMP3 9341 NM_004781 "0001921 // positive regulation of receptor recycling // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007269 // neurotransmitter secretion // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement" 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation 201337_s_at NM_004781 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004781.2 /DEF=Homo sapiens vesicle-associated membrane protein 3 (cellubrevin) (VAMP3), mRNA. /FEA=mRNA /GEN=VAMP3 /PROD=vesicle-associated membrane protein 3 /DB_XREF=gi:9257252 /UG=Hs.66708 vesicle-associated membrane protein 3 (cellubrevin) /FL=gb:BC003570.1 gb:NM_004781.2" NM_004781 vesicle-associated membrane protein 3 VAMP3 9341 NM_004781 "0001921 // positive regulation of receptor recycling // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007269 // neurotransmitter secretion // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from sequence or structural similarity /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement" 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation 201338_x_at NM_002097 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002097.1 /DEF=Homo sapiens general transcription factor IIIA (GTF3A), mRNA. /FEA=mRNA /GEN=GTF3A /PROD=general transcription factor IIIA /DB_XREF=gi:4753158 /UG=Hs.75113 general transcription factor IIIA /FL=gb:D32257.1 gb:NM_002097.1" NM_002097 general transcription factor IIIA GTF3A 2971 NM_002097 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009303 // rRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201339_s_at NM_002979 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002979.1 /DEF=Homo sapiens sterol carrier protein 2 (SCP2), mRNA. /FEA=mRNA /GEN=SCP2 /PROD=sterol carrier protein 2 /DB_XREF=gi:4506822 /UG=Hs.75760 sterol carrier protein 2 /FL=gb:M75883.1 gb:M75884.1 gb:M55421.1 gb:NM_002979.1" NM_002979 sterol carrier protein 2 SCP2 6342 NM_001007098 /// NM_001007099 /// NM_001007100 /// NM_001007250 /// NM_001193599 /// NM_001193600 /// NM_001193617 /// NM_002979 /// XM_005271103 /// XM_005271104 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0006701 // progesterone biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015914 // phospholipid transport // inferred from direct assay /// 0032385 // positive regulation of intracellular cholesterol transport // inferred from direct assay /// 0032385 // positive regulation of intracellular cholesterol transport // non-traceable author statement /// 0032959 // inositol trisphosphate biosynthetic process // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045940 // positive regulation of steroid metabolic process // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 1901373 // lipid hydroperoxide transport // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000062 // fatty-acyl-CoA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008526 // phosphatidylinositol transporter activity // inferred from direct assay /// 0015485 // cholesterol binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0032934 // sterol binding // inferred from electronic annotation /// 0033814 // propanoyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0070538 // oleic acid binding // inferred from direct assay" 201340_s_at AF010314 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF010314.1 /DEF=Homo sapiens Pig10 (PIG10) mRNA, complete cds. /FEA=mRNA /GEN=PIG10 /PROD=Pig10 /DB_XREF=gi:2415303 /UG=Hs.104925 ectodermal-neural cortex (with BTB-like domain) /FL=gb:BC000418.1 gb:AF010314.1 gb:AF059611.1 gb:AF005381.1 gb:NM_003633.1" AF010314 ectodermal-neural cortex 1 (with BTB domain) ENC1 8507 NM_001256574 /// NM_001256575 /// NM_001256576 /// NM_003633 /// NR_046318 0007275 // multicellular organismal development // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201341_at NM_003633 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003633.1 /DEF=Homo sapiens ectodermal-neural cortex (with BTB-like domain) (ENC1), mRNA. /FEA=mRNA /GEN=ENC1 /PROD=ectodermal-neural cortex (with BTB-like domain) /DB_XREF=gi:4505460 /UG=Hs.104925 ectodermal-neural cortex (with BTB-like domain) /FL=gb:BC000418.1 gb:AF010314.1 gb:AF059611.1 gb:AF005381.1 gb:NM_003633.1" NM_003633 ectodermal-neural cortex 1 (with BTB domain) ENC1 8507 NM_001256574 /// NM_001256575 /// NM_001256576 /// NM_003633 /// NR_046318 0007275 // multicellular organismal development // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201342_at NM_003093 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003093.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide C (SNRPC), mRNA. /FEA=mRNA /GEN=SNRPC /PROD=small nuclear ribonucleoprotein polypeptide C /DB_XREF=gi:4507126 /UG=Hs.1063 small nuclear ribonucleoprotein polypeptide C /FL=gb:NM_003093.1" NM_003093 small nuclear ribonucleoprotein polypeptide C SNRPC 6631 NM_003093 /// NR_029472 "0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000395 // mRNA 5'-splice site recognition // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay" 0000243 // commitment complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071004 // U2-type prespliceosome // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0030619 // U1 snRNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201343_at BE621259 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE621259 /FEA=EST /DB_XREF=gi:9892197 /DB_XREF=est:601493415F1 /CLONE=IMAGE:3895850 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 BE621259 ubiquitin-conjugating enzyme E2D 2 UBE2D2 7322 NM_003339 /// NM_181838 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201344_at BF196642 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF196642 /FEA=EST /DB_XREF=gi:11084786 /DB_XREF=est:7m93c12.x1 /CLONE=IMAGE:3562750 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 BF196642 ubiquitin-conjugating enzyme E2D 2 UBE2D2 7322 NM_003339 /// NM_181838 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201345_s_at NM_003339 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003339.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) (UBE2D2), mRNA. /FEA=mRNA /GEN=UBE2D2 /PROD=ubiquitin-conjugating enzyme E2D 2 (homologousto yeast UBC45) /DB_XREF=gi:4507774 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1" NM_003339 ubiquitin-conjugating enzyme E2D 2 UBE2D2 7322 NM_003339 /// NM_181838 0000209 // protein polyubiquitination // inferred from direct assay /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201346_at NM_024551 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024551.1 /DEF=Homo sapiens hypothetical protein FLJ21432 (FLJ21432), mRNA. /FEA=mRNA /GEN=FLJ21432 /PROD=hypothetical protein FLJ21432 /DB_XREF=gi:13375714 /UG=Hs.11641 hypothetical protein FLJ21432 /FL=gb:NM_024551.1 gb:BC004906.1" NM_024551 adiponectin receptor 2 ADIPOR2 79602 NM_024551 /// XM_005253789 /// XM_006719018 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0033211 // adiponectin-activated signaling pathway // not recorded /// 0046326 // positive regulation of glucose import // inferred from electronic annotation 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0042562 // hormone binding // not recorded /// 0042562 // hormone binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 201347_x_at NM_012203 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012203.1 /DEF=Homo sapiens glyoxylate reductasehydroxypyruvate reductase (GRHPR), mRNA. /FEA=mRNA /GEN=GRHPR /PROD=glyoxylate reductasehydroxypyruvate reductase /DB_XREF=gi:6912395 /UG=Hs.155742 glyoxylate reductasehydroxypyruvate reductase /FL=gb:AF113215.1 gb:BC000605.1 gb:BC003131.1 gb:AF146018.1 gb:AF113251.1 gb:AF134895.1 gb:NM_012203.1" NM_012203 glyoxylate reductase/hydroxypyruvate reductase GRHPR 9380 NM_012203 /// XM_005251631 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0007588 // excretion // inferred from mutant phenotype /// 0008152 // metabolic process // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043648 // dicarboxylic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046487 // glyoxylate metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0008465 // glycerate dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016618 // hydroxypyruvate reductase activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // non-traceable author statement /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0051287 // NAD binding // traceable author statement /// 0070402 // NADPH binding // inferred from direct assay" 201348_at NM_002084 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002084.2 /DEF=Homo sapiens glutathione peroxidase 3 (plasma) (GPX3), mRNA. /FEA=mRNA /GEN=GPX3 /PROD=plasma glutathione peroxidase 3 precursor /DB_XREF=gi:6006000 /UG=Hs.172153 glutathione peroxidase 3 (plasma) /FL=gb:D00632.1 gb:NM_002084.2 gb:AF217787.1" NM_002084 glutathione peroxidase 3 (plasma) GPX3 2878 NM_002084 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006982 // response to lipid hydroperoxide // traceable author statement /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // not recorded /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0008134 // transcription factor binding // traceable author statement /// 0008430 // selenium binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201349_at NM_004252 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004252.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 regulatory factor 1 (SLC9A3R1), mRNA. /FEA=mRNA /GEN=SLC9A3R1 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 3 regulatory factor 1 /DB_XREF=gi:4759139 /UG=Hs.184276 solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 regulatory factor 1 /FL=gb:BC001443.1 gb:BC003361.1 gb:AF036241.1 gb:AF015926.1 gb:NM_004252.1" NM_004252 "solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1" SLC9A3R1 9368 NM_004252 0003096 // renal sodium ion transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0010766 // negative regulation of sodium ion transport // inferred from electronic annotation /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030033 // microvillus assembly // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030643 // cellular phosphate ion homeostasis // inferred from electronic annotation /// 0032415 // regulation of sodium:proton antiporter activity // non-traceable author statement /// 0032416 // negative regulation of sodium:proton antiporter activity // inferred from electronic annotation /// 0032782 // bile acid secretion // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0034635 // glutathione transport // inferred from sequence or structural similarity /// 0044062 // regulation of excretion // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0070293 // renal absorption // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0097291 // renal phosphate ion absorption // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay /// 0097225 // sperm midpiece // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0017081 // chloride channel regulator activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0043621 // protein self-association // inferred from direct assay /// 0050780 // dopamine receptor binding // inferred from electronic annotation /// 0070851 // growth factor receptor binding // inferred from physical interaction 201350_at NM_004475 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004475.1 /DEF=Homo sapiens flotillin 2 (FLOT2), mRNA. /FEA=mRNA /GEN=FLOT2 /PROD=flotillin 2 /DB_XREF=gi:4758393 /UG=Hs.184488 flotillin 2 /FL=gb:NM_004475.1 gb:M60922.1" NM_004475 flotillin 2 FLOT2 2319 NM_004475 /// XM_005257950 /// XM_005257952 /// XM_005257953 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 1902992 // negative regulation of amyloid precursor protein catabolic process // inferred from mutant phenotype 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // non-traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016600 // flotillin complex // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031982 // vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation 201351_s_at AF070656 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF070656.1 /DEF=Homo sapiens FtsH homolog mRNA, complete cds. /FEA=mRNA /PROD=FtsH homolog /DB_XREF=gi:4454687 /UG=Hs.206521 YME1 (S.cerevisiae)-like 1 /FL=gb:AF070656.1 gb:NM_014263.1" AF070656 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201352_at NM_014263 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014263.1 /DEF=Homo sapiens YME1 (S.cerevisiae)-like 1 (YME1L1), mRNA. /FEA=mRNA /GEN=YME1L1 /PROD=YME1 (S.cerevisiae)-like 1 /DB_XREF=gi:7657688 /UG=Hs.206521 YME1 (S.cerevisiae)-like 1 /FL=gb:AF070656.1 gb:NM_014263.1" NM_014263 YME1-like 1 ATPase YME1L1 10730 NM_001253866 /// NM_014263 /// NM_139312 /// NM_139313 0006508 // proteolysis // inferred from electronic annotation /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from mutant phenotype /// 0006955 // immune response // non-traceable author statement /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042287 // MHC protein binding // non-traceable author statement /// 0042605 // peptide antigen binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201353_s_at AI653126 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI653126 /FEA=EST /DB_XREF=gi:4737105 /DB_XREF=est:wb43c08.x1 /CLONE=IMAGE:2308430 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1" AI653126 "bromodomain adjacent to zinc finger domain, 2A" BAZ2A 11176 NM_013449 /// XM_005268596 /// XM_005268597 /// XM_005268599 /// XM_005268600 /// XM_005268602 /// XM_005268603 /// XM_005268604 /// XM_006719207 /// XM_006719208 "0000183 // chromatin silencing at rDNA // inferred from sequence or structural similarity /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070869 // heterochromatin assembly involved in chromatin silencing // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0033553 // rDNA heterochromatin // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 201354_s_at AA788652 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA788652 /FEA=EST /DB_XREF=gi:2848772 /DB_XREF=est:ah30a09.s1 /CLONE=1240312 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1" AA788652 "bromodomain adjacent to zinc finger domain, 2A" BAZ2A 11176 NM_013449 /// XM_005268596 /// XM_005268597 /// XM_005268599 /// XM_005268600 /// XM_005268602 /// XM_005268603 /// XM_005268604 /// XM_006719207 /// XM_006719208 "0000183 // chromatin silencing at rDNA // inferred from sequence or structural similarity /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070869 // heterochromatin assembly involved in chromatin silencing // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0033553 // rDNA heterochromatin // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 201355_s_at NM_013449 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013449.1 /DEF=Homo sapiens bromodomain adjacent to zinc finger domain, 2A (BAZ2A), mRNA. /FEA=mRNA /GEN=BAZ2A /PROD=bromodomain adjacent to zinc finger domain, 2A /DB_XREF=gi:7304920 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1" NM_013449 "bromodomain adjacent to zinc finger domain, 2A" BAZ2A 11176 NM_013449 /// XM_005268596 /// XM_005268597 /// XM_005268599 /// XM_005268600 /// XM_005268602 /// XM_005268603 /// XM_005268604 /// XM_006719207 /// XM_006719208 "0000183 // chromatin silencing at rDNA // inferred from sequence or structural similarity /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from sequence or structural similarity /// 0034770 // histone H4-K20 methylation // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070869 // heterochromatin assembly involved in chromatin silencing // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0033553 // rDNA heterochromatin // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from sequence or structural similarity 201356_at BF129339 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF129339 /FEA=EST /DB_XREF=gi:10968379 /DB_XREF=est:601810961R1 /CLONE=IMAGE:4053975 /UG=Hs.288883 splicing factor 3a, subunit 1, 120kD /FL=gb:NM_005877.1" BF129339 "splicing factor 3a, subunit 1, 120kDa" SF3A1 10291 NM_001005409 /// NM_005877 "0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005684 // U2-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201357_s_at NM_005877 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005877.1 /DEF=Homo sapiens splicing factor 3a, subunit 1, 120kD (SF3A1), mRNA. /FEA=mRNA /GEN=SF3A1 /PROD=splicing factor 3a, subunit 1, 120kD /DB_XREF=gi:5032086 /UG=Hs.288883 splicing factor 3a, subunit 1, 120kD /FL=gb:NM_005877.1" NM_005877 "splicing factor 3a, subunit 1, 120kDa" SF3A1 10291 NM_001005409 /// NM_005877 "0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005684 // U2-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201358_s_at NM_016451 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016451.1 /DEF=Homo sapiens coatomer protein complex, subunit beta (COPB), mRNA. /FEA=mRNA /GEN=COPB /PROD=coatomer protein complex, subunit beta /DB_XREF=gi:7705368 /UG=Hs.3059 coatomer protein complex, subunit beta /FL=gb:AF084457.1 gb:AL136593.1 gb:NM_016451.1" NM_016451 "coatomer protein complex, subunit beta 1" COPB1 1315 NM_001144061 /// NM_001144062 /// NM_016451 "0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201359_at NM_016451 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016451.1 /DEF=Homo sapiens coatomer protein complex, subunit beta (COPB), mRNA. /FEA=mRNA /GEN=COPB /PROD=coatomer protein complex, subunit beta /DB_XREF=gi:7705368 /UG=Hs.3059 coatomer protein complex, subunit beta /FL=gb:AF084457.1 gb:AL136593.1 gb:NM_016451.1" NM_016451 "coatomer protein complex, subunit beta 1" COPB1 1315 NM_001144061 /// NM_001144062 /// NM_016451 "0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0030663 // COPI-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201360_at NM_000099 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000099.1 /DEF=Homo sapiens cystatin C (amyloid angiopathy and cerebral hemorrhage) (CST3), mRNA. /FEA=mRNA /GEN=CST3 /PROD=cystatin C (amyloid angiopathy and cerebralhemorrhage) /DB_XREF=gi:4503106 /UG=Hs.135084 cystatin C (amyloid angiopathy and cerebral hemorrhage) /FL=gb:NM_000099.1" NM_000099 cystatin C CST3 1471 NM_000099 /// NM_001288614 0006952 // defense response // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010703 // negative regulation of histolysis // inferred by curator /// 0010711 // negative regulation of collagen catabolic process // inferred from expression pattern /// 0010716 // negative regulation of extracellular matrix disassembly // inferred by curator /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from expression pattern /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0034103 // regulation of tissue remodeling // inferred from expression pattern /// 0043206 // extracellular fibril organization // inferred from genetic interaction /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0060311 // negative regulation of elastin catabolic process // inferred from mutant phenotype /// 0060313 // negative regulation of blood vessel remodeling // inferred from expression pattern 0005576 // extracellular region // inferred from mutant phenotype /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 201361_at NM_024092 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024092.1 /DEF=Homo sapiens hypothetical protein MGC5508 (MGC5508), mRNA. /FEA=mRNA /GEN=MGC5508 /PROD=hypothetical protein MGC5508 /DB_XREF=gi:13129091 /UG=Hs.13662 hypothetical protein MGC5508 /FL=gb:BC001309.1 gb:NM_024092.1" NM_024092 transmembrane protein 109 TMEM109 79073 NM_024092 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0071480 // cellular response to gamma radiation // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201362_at AF205218 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF205218.1 /DEF=Homo sapiens NS1-binding protein-like protein mRNA, complete cds. /FEA=mRNA /PROD=NS1-binding protein-like protein /DB_XREF=gi:12003206 /UG=Hs.197298 NS1-binding protein /FL=gb:AF205218.1 gb:AB020657.1 gb:AF161553.1 gb:NM_016389.1" AF205218 influenza virus NS1A binding protein IVNS1ABP 10625 NM_006469 /// NM_016389 /// XM_005244843 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201363_s_at AB020657 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB020657.1 /DEF=Homo sapiens mRNA for KIAA0850 protein, complete cds. /FEA=mRNA /GEN=KIAA0850 /PROD=KIAA0850 protein /DB_XREF=gi:4240188 /UG=Hs.197298 NS1-binding protein /FL=gb:AF205218.1 gb:AB020657.1 gb:AF161553.1 gb:NM_016389.1" AB020657 influenza virus NS1A binding protein IVNS1ABP 10625 NM_006469 /// NM_016389 /// XM_005244843 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201364_s_at AF242521 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF242521.1 /DEF=Homo sapiens ornithine decarboxylase antizyme mRNA, complete cds. /FEA=mRNA /PROD=ornithine decarboxylase antizyme /DB_XREF=gi:9802039 /UG=Hs.74563 ornithine decarboxylase antizyme 2 /FL=gb:AF057297.1 gb:AF242521.1 gb:NM_002537.1" AF242521 ornithine decarboxylase antizyme 2 OAZ2 4947 NM_002537 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 201365_at NM_002537 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002537.1 /DEF=Homo sapiens ornithine decarboxylase antizyme 2 (OAZ2), mRNA. /FEA=mRNA /GEN=OAZ2 /PROD=ornithine decarboxylase antizyme 2 /DB_XREF=gi:9845506 /UG=Hs.74563 ornithine decarboxylase antizyme 2 /FL=gb:AF057297.1 gb:AF242521.1 gb:NM_002537.1" NM_002537 ornithine decarboxylase antizyme 2 OAZ2 4947 NM_002537 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 201366_at NM_004034 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004034.1 /DEF=Homo sapiens annexin A7 (ANXA7), transcript variant 2, mRNA. /FEA=mRNA /GEN=ANXA7 /PROD=annexin VII isoform 2 /DB_XREF=gi:4809278 /UG=Hs.78637 annexin A7 /FL=gb:NM_004034.1" NM_004034 annexin A7 ANXA7 310 NM_001156 /// NM_004034 /// XM_005269738 /// XM_005269739 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0007599 // hemostasis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009992 // cellular water homeostasis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0035176 // social behavior // inferred from expression pattern /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0061025 // membrane fusion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 201367_s_at AI356398 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI356398 /FEA=EST /DB_XREF=gi:4108019 /DB_XREF=est:qz26f08.x1 /CLONE=IMAGE:2028039 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1 AI356398 ZFP36 ring finger protein-like 2 ZFP36L2 678 NM_006887 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000737 // negative regulation of stem cell differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201368_at U07802 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:U07802 /DEF=Human Tis11d gene, complete cds /FEA=mRNA /DB_XREF=gi:984508 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1" U07802 ZFP36 ring finger protein-like 2 ZFP36L2 678 NM_006887 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000737 // negative regulation of stem cell differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201369_s_at NM_006887 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006887.1 /DEF=Homo sapiens butyrate response factor 2 (EGF-response factor 2) (BRF2), mRNA. /FEA=mRNA /GEN=BRF2 /PROD=butyrate response factor 2 (EGF-response factor2) /DB_XREF=gi:5901899 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1" NM_006887 ZFP36 ring finger protein-like 2 ZFP36L2 678 NM_006887 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006402 // mRNA catabolic process // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from sequence or structural similarity /// 0060216 // definitive hemopoiesis // inferred from sequence or structural similarity /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity /// 2000737 // negative regulation of stem cell differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201370_s_at AU145232 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU145232 /FEA=EST /DB_XREF=gi:11006753 /DB_XREF=est:AU145232 /CLONE=HEMBA1004254 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1 AU145232 cullin 3 CUL3 8452 NM_001257197 /// NM_001257198 /// NM_003590 /// XM_006712800 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // inferred from mutant phenotype /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001831 // trophectodermal cellular morphogenesis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007369 // gastrulation // inferred from electronic annotation /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017145 // stem cell division // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0040016 // embryonic cleavage // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048208 // COPII vesicle coating // inferred from mutant phenotype /// 0051322 // anaphase // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from electronic annotation /// 0031208 // POZ domain binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201371_s_at AF062537 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF062537.1 /DEF=Homo sapiens cullin 3 mRNA, complete cds. /FEA=mRNA /PROD=cullin 3 /DB_XREF=gi:3139078 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1" AF062537 cullin 3 CUL3 8452 NM_001257197 /// NM_001257198 /// NM_003590 /// XM_006712800 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // inferred from mutant phenotype /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001831 // trophectodermal cellular morphogenesis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007369 // gastrulation // inferred from electronic annotation /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017145 // stem cell division // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0040016 // embryonic cleavage // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048208 // COPII vesicle coating // inferred from mutant phenotype /// 0051322 // anaphase // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from electronic annotation /// 0031208 // POZ domain binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201372_s_at NM_003590 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003590.1 /DEF=Homo sapiens cullin 3 (CUL3), mRNA. /FEA=mRNA /GEN=CUL3 /PROD=cullin 3 /DB_XREF=gi:4503164 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1" NM_003590 cullin 3 CUL3 8452 NM_001257197 /// NM_001257198 /// NM_003590 /// XM_006712800 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // inferred from mutant phenotype /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001831 // trophectodermal cellular morphogenesis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from sequence or structural similarity /// 0007369 // gastrulation // inferred from electronic annotation /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0017145 // stem cell division // inferred from sequence or structural similarity /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035024 // negative regulation of Rho protein signal transduction // inferred from mutant phenotype /// 0040016 // embryonic cleavage // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0048208 // COPII vesicle coating // inferred from mutant phenotype /// 0051322 // anaphase // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030332 // cyclin binding // inferred from electronic annotation /// 0031208 // POZ domain binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201373_at NM_000445 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000445.1 /DEF=Homo sapiens plectin 1, intermediate filament binding protein, 500kD (PLEC1), mRNA. /FEA=mRNA /GEN=PLEC1 /PROD=plectin 1, intermediate filament bindingprotein, 500kD /DB_XREF=gi:4505876 /UG=Hs.79706 plectin 1, intermediate filament binding protein, 500kD /FL=gb:U53204.1 gb:NM_000445.1" NM_000445 plectin PLEC 5339 NM_000445 /// NM_201378 /// NM_201379 /// NM_201380 /// NM_201381 /// NM_201382 /// NM_201383 /// NM_201384 /// XM_005250976 /// XM_005250977 /// XM_005250978 /// XM_005250979 /// XM_005250980 /// XM_005250981 /// XM_005250982 /// XM_005250983 /// XM_005250984 /// XM_006716588 /// XM_006716589 /// XM_006716590 /// XM_006716591 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // inferred from direct assay /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0046417 // chorismate metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016528 // sarcoplasm // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // traceable author statement /// 0043292 // contractile fiber // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0008307 // structural constituent of muscle // traceable author statement /// 0030506 // ankyrin binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201374_x_at AI379894 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI379894 /FEA=EST /DB_XREF=gi:4189747 /DB_XREF=est:tc64g11.x1 /CLONE=IMAGE:2069444 /UG=Hs.80350 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform /FL=gb:NM_004156.1" AI379894 "protein phosphatase 2, catalytic subunit, beta isozyme" PPP2CB 5516 NM_001009552 /// NM_004156 0006470 // protein dephosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation "0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201375_s_at NM_004156 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004156.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (PPP2CB), mRNA. /FEA=mRNA /GEN=PPP2CB /PROD=protein phosphatase 2 (formerly 2A), catalyticsubunit, beta isoform /DB_XREF=gi:4758951 /UG=Hs.80350 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform /FL=gb:NM_004156.1" NM_004156 "protein phosphatase 2, catalytic subunit, beta isozyme" PPP2CB 5516 NM_001009552 /// NM_004156 0006470 // protein dephosphorylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation "0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201376_s_at AI591354 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI591354 /FEA=EST /DB_XREF=gi:4600402 /DB_XREF=est:ts10e04.x1 /CLONE=IMAGE:2228190 /UG=Hs.808 heterogeneous nuclear ribonucleoprotein F /FL=gb:BC001432.1 gb:L28010.1 gb:NM_004966.1 AI591354 heterogeneous nuclear ribonucleoprotein F HNRNPF 3185 NM_001098204 /// NM_001098205 /// NM_001098206 /// NM_001098207 /// NM_001098208 /// NM_004966 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201377_at NM_014847 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014847.1 /DEF=Homo sapiens KIAA0144 gene product (KIAA0144), mRNA. /FEA=mRNA /GEN=KIAA0144 /PROD=KIAA0144 gene product /DB_XREF=gi:7661941 /UG=Hs.8127 KIAA0144 gene product /FL=gb:D63478.1 gb:NM_014847.1" NM_014847 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_001287815 /// NM_001287816 /// NM_014847 /// XM_005245658 /// XM_005245667 /// XM_005245668 /// XM_005245669 /// XM_005245670 /// XM_005245672 /// XM_005245673 /// XM_005245674 /// XM_006711679 /// XM_006711680 /// XM_006711681 /// XM_006711682 /// XM_006711683 /// XM_006711684 /// XM_006711685 /// XM_006711686 /// XM_006711687 /// XM_006711688 /// XM_006711689 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201378_s_at NM_014847 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014847.1 /DEF=Homo sapiens KIAA0144 gene product (KIAA0144), mRNA. /FEA=mRNA /GEN=KIAA0144 /PROD=KIAA0144 gene product /DB_XREF=gi:7661941 /UG=Hs.8127 KIAA0144 gene product /FL=gb:D63478.1 gb:NM_014847.1" NM_014847 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_001287815 /// NM_001287816 /// NM_014847 /// XM_005245658 /// XM_005245667 /// XM_005245668 /// XM_005245669 /// XM_005245670 /// XM_005245672 /// XM_005245673 /// XM_005245674 /// XM_006711679 /// XM_006711680 /// XM_006711681 /// XM_006711682 /// XM_006711683 /// XM_006711684 /// XM_006711685 /// XM_006711686 /// XM_006711687 /// XM_006711688 /// XM_006711689 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201379_s_at NM_003288 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003288.1 /DEF=Homo sapiens tumor protein D52-like 2 (TPD52L2), mRNA. /FEA=mRNA /GEN=TPD52L2 /PROD=tumor protein D52-like 2 /DB_XREF=gi:4507642 /UG=Hs.154718 tumor protein D52-like 2 /FL=gb:AF004430.1 gb:NM_003288.1" NM_003288 tumor protein D52-like 2 TPD52L2 7165 NM_001243891 /// NM_001243892 /// NM_001243894 /// NM_001243895 /// NM_003288 /// NM_199359 /// NM_199360 /// NM_199361 /// NM_199362 /// NM_199363 /// NR_045090 0042127 // regulation of cell proliferation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201380_at NM_006371 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006371.1 /DEF=Homo sapiens cartilage associated protein (CRTAP), mRNA. /FEA=mRNA /GEN=CRTAP /PROD=cartilage associated protein /DB_XREF=gi:5453600 /UG=Hs.155481 cartilage associated protein /FL=gb:NM_006371.1" NM_006371 cartilage associated protein CRTAP 10491 NM_006371 0007283 // spermatogenesis // inferred from electronic annotation /// 0018400 // peptidyl-proline hydroxylation to 3-hydroxy-L-proline // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity /// 1901874 // negative regulation of post-translational protein modification // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0032991 // macromolecular complex // inferred from sequence or structural similarity 0032403 // protein complex binding // inferred from sequence or structural similarity 201381_x_at AF057356 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF057356.1 /DEF=Homo sapiens calcyclin binding protein mRNA, complete cds. /FEA=mRNA /PROD=calcyclin binding protein /DB_XREF=gi:3063652 /UG=Hs.27258 calcyclin binding protein /FL=gb:AF314752.1 gb:AF057356.1 gb:NM_014412.1" AF057356 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 /// XM_005245092 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 201382_at NM_014412 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014412.1 /DEF=Homo sapiens calcyclin binding protein (CACYBP), mRNA. /FEA=mRNA /GEN=CACYBP /PROD=calcyclin binding protein /DB_XREF=gi:7656951 /UG=Hs.27258 calcyclin binding protein /FL=gb:AF314752.1 gb:AF057356.1 gb:NM_014412.1" NM_014412 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 /// XM_005245092 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0060416 // response to growth hormone // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 201383_s_at AL044170 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL044170 /FEA=EST /DB_XREF=gi:5935951 /DB_XREF=est:DKFZp434P2128_s1 /CLONE=DKFZp434P2128 /UG=Hs.277721 membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) /FL=gb:D30756.1 gb:NM_005899.1" AL044170 neighbor of BRCA1 gene 1 NBR1 4077 NM_001291571 /// NM_001291572 /// NM_005899 /// NM_031858 /// NM_031862 /// XM_006721903 0016236 // macroautophagy // inferred from direct assay /// 0030500 // regulation of bone mineralization // inferred from sequence or structural similarity /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from direct assay 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from sequence or structural similarity 201384_s_at NM_005899 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005899.1 /DEF=Homo sapiens membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) (M17S2), mRNA. /FEA=mRNA /GEN=M17S2 /PROD=membrane component, chromosome 17, surfacemarker 2 (ovarian carcinoma antigen CA125) /DB_XREF=gi:5174504 /UG=Hs.277721 membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) /FL=gb:D30756.1 gb:NM_005899.1" NM_005899 neighbor of BRCA1 gene 1 NBR1 4077 NM_001291571 /// NM_001291572 /// NM_005899 /// NM_031858 /// NM_031862 /// XM_006721903 0016236 // macroautophagy // inferred from direct assay /// 0030500 // regulation of bone mineralization // inferred from sequence or structural similarity /// 0032872 // regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from direct assay 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from sequence or structural similarity 201385_at NM_001358 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001358.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 (DDX15), mRNA. /FEA=mRNA /GEN=DDX15 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /DB_XREF=gi:4557516 /UG=Hs.5683 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /FL=gb:AB001636.1 gb:NM_001358.1 gb:AF279891.1" NM_001358 DEAH (Asp-Glu-Ala-His) box helicase 15 DHX15 1665 NM_001358 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201386_s_at AF279891 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF279891.1 /DEF=Homo sapiens dead box protein 15 mRNA, complete cds. /FEA=mRNA /PROD=dead box protein 15 /DB_XREF=gi:9624452 /UG=Hs.5683 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /FL=gb:AB001636.1 gb:NM_001358.1 gb:AF279891.1" AF279891 DEAH (Asp-Glu-Ala-His) box helicase 15 DHX15 1665 NM_001358 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator 0005634 // nucleus // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201387_s_at NM_004181 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004181.1 /DEF=Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mRNA. /FEA=mRNA /GEN=UCHL1 /PROD=ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase) /DB_XREF=gi:4759283 /UG=Hs.76118 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) /FL=gb:BC000332.1 gb:BC005117.1 gb:NM_004181.1" NM_004181 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) UCHL1 7345 NM_004181 0002931 // response to ischemia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007412 // axon target recognition // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019896 // axon transport of mitochondrion // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0042755 // eating behavior // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay 201388_at NM_002809 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002809.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 (PSMD3), mRNA. /FEA=mRNA /GEN=PSMD3 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 3 /DB_XREF=gi:4506228 /UG=Hs.9736 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 /FL=gb:BC000074.1 gb:BC004859.1 gb:D67025.1 gb:AF091075.1 gb:NM_002809.1" NM_002809 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 3" PSMD3 5709 NM_002809 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201389_at NM_002205 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002205.1 /DEF=Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5), mRNA. /FEA=mRNA /GEN=ITGA5 /PROD=integrin alpha 5 precursor /DB_XREF=gi:4504750 /UG=Hs.149609 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) /FL=gb:NM_002205.1" NM_002205 "integrin, alpha 5 (fibronectin receptor, alpha polypeptide)" ITGA5 3678 NM_002205 "0001525 // angiogenesis // traceable author statement /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte cell-cell adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0033631 // cell-cell adhesion mediated by integrin // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from expression pattern /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype" 0001726 // ruffle // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0071062 // alphav-beta3 integrin-vitronectin complex // traceable author statement 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // traceable author statement /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043184 // vascular endothelial growth factor receptor 2 binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 201390_s_at NM_001320 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001320.1 /DEF=Homo sapiens casein kinase 2, beta polypeptide (CSNK2B), mRNA. /FEA=mRNA /GEN=CSNK2B /PROD=casein kinase 2, beta polypeptide /DB_XREF=gi:10334850 /UG=Hs.165843 casein kinase 2, beta polypeptide /FL=gb:NM_001320.1" NM_001320 "casein kinase 2, beta polypeptide" CSNK2B 1460 NM_001282385 /// NM_001320 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032927 // positive regulation of activin receptor signaling pathway // inferred from mutant phenotype /// 0033211 // adiponectin-activated signaling pathway // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043623 // cellular protein complex assembly // non-traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // non-traceable author statement /// 0051101 // regulation of DNA binding // non-traceable author statement /// 0061154 // endothelial tube morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005956 // protein kinase CK2 complex // non-traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019887 // protein kinase regulator activity // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201391_at NM_016292 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016292.1 /DEF=Homo sapiens heat shock protein 75 (TRAP1), mRNA. /FEA=mRNA /GEN=TRAP1 /PROD=tumor necrosis factor type 1 receptor associatedprotein /DB_XREF=gi:7706484 /UG=Hs.182366 heat shock protein 75 /FL=gb:BC002994.1 gb:AF154108.1 gb:NM_016292.1" NM_016292 TNF receptor-associated protein 1 TRAP1 10131 NM_001272049 /// NM_016292 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 1901856 // negative regulation of cellular respiration // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 201392_s_at BG031974 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG031974 /FEA=EST /DB_XREF=gi:12422804 /DB_XREF=est:602300668F1 /CLONE=IMAGE:4402217 /UG=Hs.76473 insulin-like growth factor 2 receptor /FL=gb:J03528.1 gb:NM_000876.1 BG031974 insulin-like growth factor 2 receptor IGF2R 3482 NM_000876 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031995 // insulin-like growth factor II binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from direct assay 201393_s_at NM_000876 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000876.1 /DEF=Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA. /FEA=mRNA /GEN=IGF2R /PROD=insulin-like growth factor 2 receptor /DB_XREF=gi:4504610 /UG=Hs.76473 insulin-like growth factor 2 receptor /FL=gb:J03528.1 gb:NM_000876.1" NM_000876 insulin-like growth factor 2 receptor IGF2R 3482 NM_000876 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031995 // insulin-like growth factor II binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from direct assay 201394_s_at U23946 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U23946.1 /DEF=Human putative tumor suppressor (LUCA15) mRNA, complete cds. /FEA=mRNA /GEN=LUCA15 /DB_XREF=gi:1244403 /UG=Hs.201675 RNA binding motif protein 5 /FL=gb:U23946.1 gb:BC002957.1 gb:AF091263.1 gb:NM_005778.1" U23946 RNA binding motif protein 5 RBM5 10181 NM_005778 /// NR_036627 /// XM_006712917 /// XM_006712918 /// XM_006712919 /// XM_006712920 /// XR_427245 "0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201395_at NM_005778 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005778.1 /DEF=Homo sapiens RNA binding motif protein 5 (RBM5), mRNA. /FEA=mRNA /GEN=RBM5 /PROD=RNA binding motif protein 5 /DB_XREF=gi:5032030 /UG=Hs.201675 RNA binding motif protein 5 /FL=gb:U23946.1 gb:BC002957.1 gb:AF091263.1 gb:NM_005778.1" NM_005778 RNA binding motif protein 5 RBM5 10181 NM_005778 /// NR_036627 /// XM_006712917 /// XM_006712918 /// XM_006712919 /// XM_006712920 /// XR_427245 "0000245 // spliceosomal complex assembly // inferred from direct assay /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201396_s_at NM_003021 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003021.2 /DEF=Homo sapiens small glutamine-rich tetratricopeptide repeat (TPR)-containing (SGT), mRNA. /FEA=mRNA /GEN=SGT /PROD=small glutamine-rich tetratricopeptide /DB_XREF=gi:13259553 /UG=Hs.203910 small glutamine-rich tetratricopeptide repeat (TPR)-containing /FL=gb:BC000390.1 gb:NM_003021.2 gb:BC005165.1 gb:AL050156.1" NM_003021 "small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha" SGTA 6449 NM_003021 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201397_at NM_006623 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006623.1 /DEF=Homo sapiens phosphoglycerate dehydrogenase (PHGDH), mRNA. /FEA=mRNA /GEN=PHGDH /PROD=phosphoglycerate dehydrogenase /DB_XREF=gi:5729973 /UG=Hs.3343 phosphoglycerate dehydrogenase /FL=gb:BC000303.1 gb:BC001349.1 gb:AF006043.1 gb:NM_006623.1 gb:AF171237.1" NM_006623 phosphoglycerate dehydrogenase PHGDH 26227 NM_006623 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006544 // glycine metabolic process // inferred from electronic annotation /// 0006563 // L-serine metabolic process // inferred from electronic annotation /// 0006564 // L-serine biosynthetic process // traceable author statement /// 0006566 // threonine metabolic process // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021782 // glial cell development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022402 // cell cycle process // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070314 // G1 to G0 transition // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004617 // phosphoglycerate dehydrogenase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201398_s_at BC000687 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000687.1 /DEF=Homo sapiens, translocating chain-associating membrane protein, clone MGC:784, mRNA, complete cds. /FEA=mRNA /PROD=translocating chain-associating membraneprotein /DB_XREF=gi:12653796 /UG=Hs.4147 translocating chain-associating membrane protein /FL=gb:BC000687.1 gb:NM_014294.1" BC000687 translocation associated membrane protein 1 TRAM1 23471 NM_014294 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201399_s_at NM_014294 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014294.1 /DEF=Homo sapiens translocating chain-associating membrane protein (TRAM), mRNA. /FEA=mRNA /GEN=TRAM /PROD=translocating chain-associating membraneprotein /DB_XREF=gi:7657654 /UG=Hs.4147 translocating chain-associating membrane protein /FL=gb:BC000687.1 gb:NM_014294.1" NM_014294 translocation associated membrane protein 1 TRAM1 23471 NM_014294 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201400_at NM_002795 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002795.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 3 (PSMB3), mRNA. /FEA=mRNA /GEN=PSMB3 /PROD=proteasome (prosome, macropain) subunit, betatype, 3 /DB_XREF=gi:4506196 /UG=Hs.82793 proteasome (prosome, macropain) subunit, beta type, 3 /FL=gb:NM_002795.1 gb:D26598.1" NM_002795 "proteasome (prosome, macropain) subunit, beta type, 3" PSMB3 5691 NM_002795 /// NR_104194 /// NR_104195 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201401_s_at M80776 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M80776.1 /DEF=Human beta-adrenergic receptor kinase 1 mRNA, complete cds. /FEA=mRNA /GEN=receptor kinase /PROD=receptor kinase /DB_XREF=gi:179334 /UG=Hs.83636 adrenergic, beta, receptor kinase 1 /FL=gb:M80776.1 gb:NM_001619.2" M80776 "adrenergic, beta, receptor kinase 1" ADRBK1 156 NM_001619 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0003108 // negative regulation of the force of heart contraction by chemical signal // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0033605 // positive regulation of catecholamine secretion // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from sequence or structural similarity /// 0031755 // Edg-2 lysophosphatidic acid receptor binding // inferred from direct assay /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation" 201402_at NM_001619 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001619.2 /DEF=Homo sapiens adrenergic, beta, receptor kinase 1 (ADRBK1), mRNA. /FEA=mRNA /GEN=ADRBK1 /PROD=beta adrenergic receptor kinase 1 /DB_XREF=gi:6138971 /UG=Hs.83636 adrenergic, beta, receptor kinase 1 /FL=gb:M80776.1 gb:NM_001619.2" NM_001619 "adrenergic, beta, receptor kinase 1" ADRBK1 156 NM_001619 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0003108 // negative regulation of the force of heart contraction by chemical signal // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007213 // G-protein coupled acetylcholine receptor signaling pathway // inferred from sequence or structural similarity /// 0007217 // tachykinin receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0033605 // positive regulation of catecholamine secretion // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031694 // alpha-2A adrenergic receptor binding // inferred from sequence or structural similarity /// 0031755 // Edg-2 lysophosphatidic acid receptor binding // inferred from direct assay /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation" 201403_s_at NM_004528 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004528.1 /DEF=Homo sapiens microsomal glutathione S-transferase 3 (MGST3), mRNA. /FEA=mRNA /GEN=MGST3 /PROD=microsomal glutathione S-transferase 3 /DB_XREF=gi:4758713 /UG=Hs.111811 microsomal glutathione S-transferase 3 /FL=gb:BC000505.1 gb:BC003034.1 gb:AF026977.1 gb:NM_004528.1" NM_004528 microsomal glutathione S-transferase 3 MGST3 4259 NM_004528 /// XM_005245174 0006629 // lipid metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // not recorded /// 0055114 // oxidation-reduction process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005635 // nuclear envelope // not recorded /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // not recorded /// 0004601 // peroxidase activity // traceable author statement /// 0004602 // glutathione peroxidase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation 201404_x_at BC000268 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000268.1 /DEF=Homo sapiens, proteasome (prosome, macropain) subunit, beta type, 2, clone MGC:1664, mRNA, complete cds. /FEA=mRNA /PROD=proteasome (prosome, macropain) subunit, betatype, 2 /DB_XREF=gi:12653014 /UG=Hs.1390 proteasome (prosome, macropain) subunit, beta type, 2 /FL=gb:BC000268.1 gb:NM_002794.1 gb:D26599.1" BC000268 "proteasome (prosome, macropain) subunit, beta type, 2" PSMB2 5690 NM_001199779 /// NM_001199780 /// NM_002794 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201405_s_at NM_006833 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006833.1 /DEF=Homo sapiens COP9 subunit 6 (MOV34 homolog, 34 kD) (MOV34-34KD), mRNA. /FEA=mRNA /GEN=MOV34-34KD /PROD=COP9 subunit 6 (MOV34 homolog, 34 kD) /DB_XREF=gi:5803095 /UG=Hs.15591 COP9 subunit 6 (MOV34 homolog, 34 kD) /FL=gb:BC002520.1 gb:U70735.1 gb:NM_006833.1" NM_006833 COP9 signalosome subunit 6 COPS6 10980 NM_006833 0010388 // cullin deneddylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201406_at NM_021029 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021029.1 /DEF=Homo sapiens ribosomal protein L44 (RPL44), mRNA. /FEA=mRNA /GEN=RPL44 /PROD=ribosomal protein L44 /DB_XREF=gi:10445222 /UG=Hs.178391 ribosomal protein L44 /FL=gb:NM_021029.1 gb:BC001781.1" NM_021029 ribosomal protein L36a /// RPL36A-HNRNPH2 readthrough RPL36A /// RPL36A-HNRNPH2 6173 /// 100529097 NM_001199972 /// NM_001199973 /// NM_001199974 /// NM_021029 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201407_s_at AI186712 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI186712 /FEA=EST /DB_XREF=gi:3737350 /DB_XREF=est:qe82f01.x1 /CLONE=IMAGE:1745497 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1" AI186712 "protein phosphatase 1, catalytic subunit, beta isozyme" PPP1CB 5500 NM_002709 /// NM_206876 /// NM_206877 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017018 // myosin phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050115 // myosin-light-chain-phosphatase activity // inferred from direct assay 201408_at W67887 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:W67887 /FEA=EST /DB_XREF=gi:1376776 /DB_XREF=est:zd38c11.s1 /CLONE=IMAGE:342932 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1" W67887 "protein phosphatase 1, catalytic subunit, beta isozyme" PPP1CB 5500 NM_002709 /// NM_206876 /// NM_206877 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017018 // myosin phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050115 // myosin-light-chain-phosphatase activity // inferred from direct assay 201409_s_at NM_002709 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002709.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), mRNA. /FEA=mRNA /GEN=PPP1CB /PROD=protein phosphatase 1, catalytic subunit, betaisoform /DB_XREF=gi:4506004 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1" NM_002709 "protein phosphatase 1, catalytic subunit, beta isozyme" PPP1CB 5500 NM_002709 /// NM_206876 /// NM_206877 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0005981 // regulation of glycogen catabolic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0000164 // protein phosphatase type 1 complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0017018 // myosin phosphatase activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050115 // myosin-light-chain-phosphatase activity // inferred from direct assay 201410_at AI983043 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI983043 /FEA=EST /DB_XREF=gi:5810262 /DB_XREF=est:wz30b11.x1 /CLONE=IMAGE:2559549 /UG=Hs.246885 hypothetical protein FLJ20783 /FL=gb:NM_017958.1 AI983043 "pleckstrin homology domain containing, family B (evectins) member 2" PLEKHB2 55041 NM_001031706 /// NM_001100623 /// NM_001267062 /// NM_001267063 /// NM_001267064 /// NM_001267065 /// NM_001267066 /// NM_001267067 /// NM_001267068 /// NM_017958 /// NR_049789 /// NR_049790 /// NR_049791 /// NR_049792 /// XM_006712607 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 201411_s_at NM_017958 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017958.1 /DEF=Homo sapiens hypothetical protein FLJ20783 (FLJ20783), mRNA. /FEA=mRNA /GEN=FLJ20783 /PROD=hypothetical protein FLJ20783 /DB_XREF=gi:8923679 /UG=Hs.246885 hypothetical protein FLJ20783 /FL=gb:NM_017958.1" NM_017958 "pleckstrin homology domain containing, family B (evectins) member 2" PLEKHB2 55041 NM_001031706 /// NM_001100623 /// NM_001267062 /// NM_001267063 /// NM_001267064 /// NM_001267065 /// NM_001267066 /// NM_001267067 /// NM_001267068 /// NM_017958 /// NR_049789 /// NR_049790 /// NR_049791 /// NR_049792 /// XM_006712607 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005543 // phospholipid binding // inferred from electronic annotation 201412_at NM_014045 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014045.1 /DEF=Homo sapiens DKFZP564C1940 protein (DKFZP564C1940), mRNA. /FEA=mRNA /GEN=DKFZP564C1940 /PROD=DKFZP564C1940 protein /DB_XREF=gi:13027587 /UG=Hs.3804 DKFZP564C1940 protein /FL=gb:BC000424.1 gb:NM_014045.1 gb:AF131760.1" NM_014045 low density lipoprotein receptor-related protein 10 LRP10 26020 NM_014045 /// XM_005267510 0006897 // endocytosis // inferred from electronic annotation 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201413_at NM_000414 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000414.1 /DEF=Homo sapiens hydroxysteroid (17-beta) dehydrogenase 4 (HSD17B4), mRNA. /FEA=mRNA /GEN=HSD17B4 /PROD=hydroxysteroid (17-beta) dehydrogenase 4 /DB_XREF=gi:4504504 /UG=Hs.75441 hydroxysteroid (17-beta) dehydrogenase 4 /FL=gb:BC003098.1 gb:NM_000414.1" NM_000414 hydroxysteroid (17-beta) dehydrogenase 4 HSD17B4 3295 NM_000414 /// NM_001199291 /// NM_001199292 /// NM_001292027 /// NM_001292028 0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // traceable author statement /// 0008209 // androgen metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0036111 // very long-chain fatty-acyl-CoA metabolic process // inferred from direct assay /// 0036112 // medium-chain fatty-acyl-CoA metabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0060009 // Sertoli cell development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from direct assay /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from mutant phenotype /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016508 // long-chain-enoyl-CoA hydratase activity // inferred from direct assay /// 0016508 // long-chain-enoyl-CoA hydratase activity // traceable author statement /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0032934 // sterol binding // inferred from electronic annotation /// 0033989 // 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044594 // 17-beta-hydroxysteroid dehydrogenase (NAD+) activity // inferred from direct assay" 201414_s_at NM_005969 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005969.1 /DEF=Homo sapiens nucleosome assembly protein 1-like 4 (NAP1L4), mRNA. /FEA=mRNA /GEN=NAP1L4 /PROD=nucleosome assembly protein 1-like 4 /DB_XREF=gi:5174612 /UG=Hs.78103 nucleosome assembly protein 1-like 4 /FL=gb:U77456.1 gb:NM_005969.1" NM_005969 nucleosome assembly protein 1-like 4 NAP1L4 4676 NM_005969 0006334 // nucleosome assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 201415_at NM_000178 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000178.1 /DEF=Homo sapiens glutathione synthetase (GSS), mRNA. /FEA=mRNA /GEN=GSS /PROD=glutathione synthetase /DB_XREF=gi:4504168 /UG=Hs.82327 glutathione synthetase /FL=gb:U34683.1 gb:NM_000178.1" NM_000178 glutathione synthetase GSS 2937 NM_000178 /// XM_005260406 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004363 // glutathione synthase activity // traceable author statement /// 0005524 // ATP binding // inferred from direct assay /// 0016594 // glycine binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043295 // glutathione binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201416_at BG528420 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG528420 /FEA=EST /DB_XREF=gi:13519957 /DB_XREF=est:602579853F1 /CLONE=IMAGE:4719060 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1 BG528420 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 "0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201417_at AL136179 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL136179 /DEF=Human DNA sequence from clone RP3-322L4 on chromosome 6. Contains the SOX4 gene for SRY (sex determining region Y)-box 4, a pseudogene similar to predicted fly, worm and yeast genes, ESTs, STSs, GSSs and four CpG islands /FEA=mRNA /DB_XREF=gi:8649149 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1" AL136179 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 "0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201418_s_at NM_003107 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003107.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 4 (SOX4), mRNA. /FEA=mRNA /GEN=SOX4 /PROD=SRY (sex determining region Y)-box 4 /DB_XREF=gi:4507162 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1" NM_003107 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 "0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201419_at NM_004656 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004656.1 /DEF=Homo sapiens BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1), mRNA. /FEA=mRNA /GEN=BAP1 /PROD=BRCA1 associated protein-1 (ubiquitincarboxy-terminal hydrolase) /DB_XREF=gi:4757835 /UG=Hs.106674 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) /FL=gb:BC001596.1 gb:AF045581.1 gb:NM_004656.1" NM_004656 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) BAP1 8314 NM_004656 0001558 // regulation of cell growth // inferred from mutant phenotype /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0035520 // monoubiquitinated protein deubiquitination // inferred from direct assay /// 0035522 // monoubiquitinated histone H2A deubiquitination // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0071108 // protein K48-linked deubiquitination // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035517 // PR-DUB complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // non-traceable author statement /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201420_s_at BF975273 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF975273 /FEA=EST /DB_XREF=gi:12342488 /DB_XREF=est:602244783F1 /CLONE=IMAGE:4335765 /UG=Hs.11039 hypothetical protein MGC2722 /FL=gb:BC001679.1 gb:NM_024102.1 BF975273 WD repeat domain 77 WDR77 79084 NM_024102 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from genetic interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from genetic interaction /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034709 // methylosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from genetic interaction 201421_s_at NM_024102 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024102.1 /DEF=Homo sapiens hypothetical protein MGC2722 (MGC2722), mRNA. /FEA=mRNA /GEN=MGC2722 /PROD=hypothetical protein MGC2722 /DB_XREF=gi:13129109 /UG=Hs.11039 hypothetical protein MGC2722 /FL=gb:BC001679.1 gb:NM_024102.1" NM_024102 WD repeat domain 77 WDR77 79084 NM_024102 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from genetic interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from genetic interaction /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0034709 // methylosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from genetic interaction 201422_at NM_006332 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006332.1 /DEF=Homo sapiens interferon, gamma-inducible protein 30 (IFI30), mRNA. /FEA=mRNA /GEN=IFI30 /PROD=interferon, gamma-inducible protein 30 /DB_XREF=gi:5453695 /UG=Hs.14623 interferon, gamma-inducible protein 30 /FL=gb:J03909.1 gb:NM_006332.1 gb:AF097362.1" NM_006332 "interferon, gamma-inducible protein 30 /// phosphoinositide-3-kinase, regulatory subunit 2 (beta)" IFI30 /// PIK3R2 5296 /// 10437 NM_005027 /// NM_006332 /// NR_073517 0002376 // immune system process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // inferred from sequence or structural similarity /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0005515 // protein binding // inferred from physical interaction /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016667 // oxidoreductase activity, acting on a sulfur group of donors // inferred from mutant phenotype /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation" 201423_s_at AL037208 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL037208 /FEA=EST /DB_XREF=gi:5406648 /DB_XREF=est:DKFZp564B1169_s1 /CLONE=DKFZp564B1169 /UG=Hs.183874 cullin 4A /FL=gb:NM_003589.1 gb:AF077188.1 AL037208 cullin 4A CUL4A 8451 NM_001008895 /// NM_001278513 /// NM_001278514 /// NM_003589 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201424_s_at NM_003589 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003589.1 /DEF=Homo sapiens cullin 4A (CUL4A), mRNA. /FEA=mRNA /GEN=CUL4A /PROD=cullin 4A /DB_XREF=gi:11140810 /UG=Hs.183874 cullin 4A /FL=gb:NM_003589.1 gb:AF077188.1" NM_003589 cullin 4A CUL4A 8451 NM_001008895 /// NM_001278513 /// NM_001278514 /// NM_003589 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031464 // Cul4A-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201425_at NM_000690 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000690.1 /DEF=Homo sapiens aldehyde dehydrogenase 2, mitochondrial (ALDH2), mRNA. /FEA=mRNA /GEN=ALDH2 /PROD=aldehyde dehydrogenase 2, mitochondrial /DB_XREF=gi:4502032 /UG=Hs.195432 aldehyde dehydrogenase 2 family (mitochondrial) /FL=gb:BC002967.1 gb:NM_000690.1" NM_000690 aldehyde dehydrogenase 2 family (mitochondrial) ALDH2 217 NM_000690 /// NM_001204889 0005975 // carbohydrate metabolic process // traceable author statement /// 0006066 // alcohol metabolic process // traceable author statement /// 0006068 // ethanol catabolic process // inferred from electronic annotation /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004029 // aldehyde dehydrogenase (NAD) activity // not recorded /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation" 201426_s_at AI922599 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI922599 /FEA=EST /DB_XREF=gi:5658563 /DB_XREF=est:wm90b11.x1 /CLONE=IMAGE:2443197 /UG=Hs.297753 vimentin /FL=gb:BC000163.2 gb:NM_003380.1 AI922599 vimentin VIM 7431 NM_003380 /// XM_006717500 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0045103 // intermediate filament-based process // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0060020 // Bergmann glial cell differentiation // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005882 // intermediate filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031252 // cell leading edge // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from direct assay /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 201427_s_at NM_005410 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005410.1 /DEF=Homo sapiens selenoprotein P, plasma, 1 (SEPP1), mRNA. /FEA=mRNA /GEN=SEPP1 /PROD=selenoprotein P precursor /DB_XREF=gi:4885590 /UG=Hs.3314 selenoprotein P, plasma, 1 /FL=gb:NM_005410.1" NM_005410 "selenoprotein P, plasma, 1" SEPP1 6414 NM_001085486 /// NM_001093726 /// NM_005410 0001887 // selenium compound metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008430 // selenium binding // inferred from electronic annotation 201428_at NM_001305 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001305.1 /DEF=Homo sapiens claudin 4 (CLDN4), mRNA. /FEA=mRNA /GEN=CLDN4 /PROD=claudin 4 /DB_XREF=gi:4502876 /UG=Hs.5372 claudin 4 /FL=gb:BC000671.1 gb:AB000712.1 gb:NM_001305.1" NM_001305 claudin 4 CLDN4 1364 NM_001305 0007165 // signal transduction // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0032570 // response to progesterone // inferred from electronic annotation /// 0061436 // establishment of skin barrier // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity 201429_s_at NM_000998 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000998.1 /DEF=Homo sapiens ribosomal protein L37a (RPL37A), mRNA. /FEA=mRNA /GEN=RPL37A /PROD=ribosomal protein L37a /DB_XREF=gi:4506642 /UG=Hs.5566 ribosomal protein L37a /FL=gb:BC000555.1 gb:L06499.1 gb:NM_000998.1" NM_000998 ribosomal protein L37a RPL37A 6168 NM_000998 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201430_s_at W72516 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:W72516 /FEA=EST /DB_XREF=gi:1382173 /DB_XREF=est:zd64g05.s1 /CLONE=IMAGE:345464 /UG=Hs.74566 dihydropyrimidinase-like 3 /FL=gb:D78014.1 gb:NM_001387.1 W72516 dihydropyrimidinase-like 3 DPYSL3 1809 NM_001197294 /// NM_001387 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from sequence or structural similarity /// 0070382 // exocytic vesicle // inferred from sequence or structural similarity "0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 201431_s_at NM_001387 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001387.1 /DEF=Homo sapiens dihydropyrimidinase-like 3 (DPYSL3), mRNA. /FEA=mRNA /GEN=DPYSL3 /PROD=dihydropyrimidinase-like 3 /DB_XREF=gi:4503378 /UG=Hs.74566 dihydropyrimidinase-like 3 /FL=gb:D78014.1 gb:NM_001387.1" NM_001387 dihydropyrimidinase-like 3 DPYSL3 1809 NM_001197294 /// NM_001387 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from sequence or structural similarity /// 0070382 // exocytic vesicle // inferred from sequence or structural similarity "0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0035374 // chondroitin sulfate binding // inferred from sequence or structural similarity /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 201432_at NM_001752 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001752.1 /DEF=Homo sapiens catalase (CAT), mRNA. /FEA=mRNA /GEN=CAT /PROD=catalase /DB_XREF=gi:4557013 /UG=Hs.76359 catalase /FL=gb:NM_001752.1" NM_001752 catalase CAT 847 NM_001752 0000302 // response to reactive oxygen species // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0042697 // menopause // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0005782 // peroxisomal matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004046 // aminoacylase activity // inferred from electronic annotation /// 0004096 // catalase activity // inferred from direct assay /// 0004096 // catalase activity // traceable author statement /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay" 201433_s_at NM_014754 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014754.1 /DEF=Homo sapiens phosphatidylserine synthase 1 (PTDSS1), mRNA. /FEA=mRNA /GEN=PTDSS1 /PROD=phosphatidylserine synthase 1 /DB_XREF=gi:7662646 /UG=Hs.77329 phosphatidylserine synthase 1 /FL=gb:BC004192.1 gb:BC004390.1 gb:D14694.1 gb:NM_014754.1" NM_014754 phosphatidylserine synthase 1 PTDSS1 9791 NM_001290225 /// NM_014754 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006659 // phosphatidylserine biosynthetic process // inferred from electronic annotation /// 0006659 // phosphatidylserine biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation 201434_at NM_003314 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003314.1 /DEF=Homo sapiens tetratricopeptide repeat domain 1 (TTC1), mRNA. /FEA=mRNA /GEN=TTC1 /PROD=tetratricopeptide repeat domain 1 /DB_XREF=gi:4507710 /UG=Hs.7733 tetratricopeptide repeat domain 1 /FL=gb:BC000942.1 gb:U46570.1 gb:NM_003314.1" NM_003314 tetratricopeptide repeat domain 1 TTC1 7265 NM_001282500 /// NM_003314 0006457 // protein folding // non-traceable author statement 0005778 // peroxisomal membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 201435_s_at AW268640 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW268640 /FEA=EST /DB_XREF=gi:6655670 /DB_XREF=est:xv52a03.x1 /CLONE=IMAGE:2816716 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 AW268640 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 /// XM_006714126 /// XM_006714127 "0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype" 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0033391 // chromatoid body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0031370 // eukaryotic initiation factor 4G binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201436_at AI742789 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI742789 /FEA=EST /DB_XREF=gi:5111077 /DB_XREF=est:wg46c05.x1 /CLONE=IMAGE:2368136 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 AI742789 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 /// XM_006714126 /// XM_006714127 "0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype" 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0033391 // chromatoid body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0031370 // eukaryotic initiation factor 4G binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201437_s_at NM_001968 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001968.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), mRNA. /FEA=mRNA /GEN=EIF4E /PROD=eukaryotic translation initiation factor 4E /DB_XREF=gi:4503534 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1" NM_001968 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 /// XM_006714126 /// XM_006714127 "0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype" 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay /// 0016442 // RISC complex // inferred from direct assay /// 0033391 // chromatoid body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0031370 // eukaryotic initiation factor 4G binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201438_at NM_004369 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004369.1 /DEF=Homo sapiens collagen, type VI, alpha 3 (COL6A3), mRNA. /FEA=mRNA /GEN=COL6A3 /PROD=collagen, type VI, alpha 3 /DB_XREF=gi:4758027 /UG=Hs.80988 collagen, type VI, alpha 3 /FL=gb:NM_004369.1" NM_004369 "collagen, type VI, alpha 3" COL6A3 1293 NM_004369 /// NM_057164 /// NM_057165 /// NM_057166 /// NM_057167 /// XM_005246065 /// XM_005246066 /// XM_006712253 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005589 // collagen type VI trimer // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 201439_at NM_004193 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004193.1 /DEF=Homo sapiens golgi-specific brefeldin A resistance factor 1 (GBF1), mRNA. /FEA=mRNA /GEN=GBF1 /PROD=golgi-specific brefeldin A resistance factor 1 /DB_XREF=gi:4758415 /UG=Hs.155499 golgi-specific brefeldin A resistance factor 1 /FL=gb:AF068755.1 gb:NM_004193.1" NM_004193 golgi brefeldin A resistant guanine nucleotide exchange factor 1 GBF1 8729 NM_001199378 /// NM_001199379 /// NM_004193 /// XM_005270261 /// XM_006718047 /// XM_006718048 /// XM_006718049 /// XM_006718050 /// XM_006718051 "0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // traceable author statement /// 0061024 // membrane organization // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0016020 // membrane // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201440_at NM_004818 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004818.1 /DEF=Homo sapiens prp28, U5 snRNP 100 kd protein (U5-100K), mRNA. /FEA=mRNA /GEN=U5-100K /PROD=prp28, U5 snRNP 100 kd protein /DB_XREF=gi:4759277 /UG=Hs.168103 prp28, U5 snRNP 100 kd protein /FL=gb:BC002366.1 gb:AF026402.1 gb:NM_004818.1" NM_004818 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 DDX23 9416 NM_004818 /// XM_006719699 "0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201441_at NM_001863 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001863.2 /DEF=Homo sapiens cytochrome c oxidase subunit VIb (COX6B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX6B /PROD=cytochrome c oxidase subunit VIb /DB_XREF=gi:6680989 /UG=Hs.174031 cytochrome c oxidase subunit VIb /FL=gb:BC001015.1 gb:BC002478.1 gb:NM_001863.2" NM_001863 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) COX6B1 1340 NM_001863 0021762 // substantia nigra development // inferred from expression pattern /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // non-traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // non-traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // non-traceable author statement 201442_s_at AF248966 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF248966.1 /DEF=Homo sapiens HT028 mRNA, complete cds. /FEA=mRNA /PROD=HT028 /DB_XREF=gi:12005668 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1" AF248966 "ATPase, H+ transporting, lysosomal accessory protein 2" ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0021903 // rostrocaudal neural tube patterning // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048069 // eye pigmentation // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 201443_s_at AF248966 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF248966.1 /DEF=Homo sapiens HT028 mRNA, complete cds. /FEA=mRNA /PROD=HT028 /DB_XREF=gi:12005668 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1" AF248966 "ATPase, H+ transporting, lysosomal accessory protein 2" ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0021903 // rostrocaudal neural tube patterning // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048069 // eye pigmentation // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 201444_s_at NM_005765 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005765.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 (APT6M8-9), mRNA. /FEA=mRNA /GEN=APT6M8-9 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) membrane sector associated protein M8-9 /DB_XREF=gi:5031590 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1" NM_005765 "ATPase, H+ transporting, lysosomal accessory protein 2" ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0021903 // rostrocaudal neural tube patterning // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from direct assay /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048069 // eye pigmentation // inferred from mutant phenotype /// 0060323 // head morphogenesis // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 201445_at NM_001839 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001839.1 /DEF=Homo sapiens calponin 3, acidic (CNN3), mRNA. /FEA=mRNA /GEN=CNN3 /PROD=calponin 3 /DB_XREF=gi:4502922 /UG=Hs.194662 calponin 3, acidic /FL=gb:NM_001839.1" NM_001839 "calponin 3, acidic" CNN3 1266 NM_001286055 /// NM_001286056 /// NM_001839 /// XM_006710335 0006939 // smooth muscle contraction // non-traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from electronic annotation 0014069 // postsynaptic density // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // non-traceable author statement /// 0008017 // microtubule binding // inferred from electronic annotation /// 0030172 // troponin C binding // non-traceable author statement 201446_s_at BF692742 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF692742 /FEA=EST /DB_XREF=gi:11978150 /DB_XREF=est:602079823F1 /CLONE=IMAGE:4244524 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 BF692742 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 "0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201447_at H96549 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:H96549 /FEA=EST /DB_XREF=gi:1110035 /DB_XREF=est:yw01c09.s1 /CLONE=IMAGE:250960 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 H96549 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 "0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201448_at AL046419 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL046419 /FEA=EST /DB_XREF=gi:5434493 /DB_XREF=est:DKFZp434N247_s1 /CLONE=DKFZp434N247 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 AL046419 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 "0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201449_at AL567227 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL567227 /FEA=EST /DB_XREF=gi:12920378 /DB_XREF=est:AL567227 /CLONE=CS0DF027YA11 (3 prime) /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 AL567227 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 "0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201450_s_at NM_022037 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022037.1 /DEF=Homo sapiens TIA1 cytotoxic granule-associated RNA-binding protein (TIA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=TIA1 /PROD=TIA1 protein, isoform 1 /DB_XREF=gi:11863160 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1" NM_022037 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 /// XM_005264524 /// XM_005264525 /// XM_005264526 /// XM_005264527 /// XM_005264528 /// XM_005264530 /// XM_005264531 /// XM_005264532 /// XM_005264533 /// XR_244953 /// XR_244954 /// XR_244955 "0006915 // apoptotic process // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0042036 // negative regulation of cytokine biosynthetic process // inferred from electronic annotation /// 0048024 // regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0097165 // nuclear stress granule // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201451_x_at D78132 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:D78132.1 /DEF=Homo sapiens mRNA for ras-related GTP-binding protein, complete cds. /FEA=mRNA /GEN=Rheb /PROD=ras-related GTP-binding protein /DB_XREF=gi:1772344 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1" D78132 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201452_at AW138374 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW138374 /FEA=EST /DB_XREF=gi:6142692 /DB_XREF=est:UI-H-BI1-adb-e-09-0-UI.s1 /CLONE=IMAGE:2716145 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1 AW138374 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201453_x_at NM_005614 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005614.1 /DEF=Homo sapiens Ras homolog enriched in brain 2 (RHEB2), mRNA. /FEA=mRNA /GEN=RHEB2 /PROD=Ras homolog enriched in brain 2 /DB_XREF=gi:5032040 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1" NM_005614 Ras homolog enriched in brain RHEB 6009 NM_005614 /// XM_006716081 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201454_s_at AW055008 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW055008 /FEA=EST /DB_XREF=gi:5920711 /DB_XREF=est:wy98c09.x1 /CLONE=IMAGE:2556592 /UG=Hs.293007 aminopeptidase puromycin sensitive /FL=gb:NM_006310.1 AW055008 aminopeptidase puromycin sensitive NPEPPS 9520 NM_006310 /// XM_006722187 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201455_s_at AJ132583 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AJ132583.1 /DEF=Homo sapiens mRNA for puromycin sensitive aminopeptidase, partial. /FEA=mRNA /PROD=puromycin sensitive aminopeptidase /DB_XREF=gi:4210725 /UG=Hs.293007 aminopeptidase puromycin sensitive /FL=gb:NM_006310.1" AJ132583 aminopeptidase puromycin sensitive NPEPPS 9520 NM_006310 /// XM_006722187 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201456_s_at AU160695 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU160695 /FEA=EST /DB_XREF=gi:11022216 /DB_XREF=est:AU160695 /CLONE=Y79AA1002240 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1" AU160695 BUB3 mitotic checkpoint protein BUB3 9184 NM_001007793 /// NM_004725 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051983 // regulation of chromosome segregation // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement" 0005515 // protein binding // inferred from physical interaction 201457_x_at AF081496 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF081496.1 /DEF=Homo sapiens kinetochore protein BUB3 (BUB3) mRNA, complete cds. /FEA=mRNA /GEN=BUB3 /PROD=kinetochore protein BUB3 /DB_XREF=gi:3639059 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1" AF081496 BUB3 mitotic checkpoint protein BUB3 9184 NM_001007793 /// NM_004725 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051983 // regulation of chromosome segregation // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement" 0005515 // protein binding // inferred from physical interaction 201458_s_at NM_004725 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004725.1 /DEF=Homo sapiens BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog (BUB3), mRNA. /FEA=mRNA /GEN=BUB3 /PROD=BUB3 (budding uninhibited by benzimidazoles 3,yeast) homolog /DB_XREF=gi:4757879 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1" NM_004725 BUB3 mitotic checkpoint protein BUB3 9184 NM_001007793 /// NM_004725 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051983 // regulation of chromosome segregation // inferred from electronic annotation /// 0071173 // spindle assembly checkpoint // inferred from direct assay "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement" 0005515 // protein binding // inferred from physical interaction 201459_at NM_006666 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006666.1 /DEF=Homo sapiens RuvB (E coli homolog)-like 2 (RUVBL2), mRNA. /FEA=mRNA /GEN=RUVBL2 /PROD=RuvB (E coli homolog)-like 2 /DB_XREF=gi:5730022 /UG=Hs.6455 RuvB (E coli homolog)-like 2 /FL=gb:BC000428.1 gb:BC004531.1 gb:AB024301.1 gb:AF151804.1 gb:AF155138.1 gb:NM_006666.1 gb:AL136743.1 gb:AF124607.1" NM_006666 RuvB-like AAA ATPase 2 RUVBL2 10856 NM_006666 /// XM_005258426 /// XM_005258427 /// XM_005258428 "0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0071169 // establishment of protein localization to chromatin // inferred from mutant phenotype /// 0071392 // cellular response to estradiol stimulus // inferred from mutant phenotype /// 0071733 // transcriptional activation by promoter-enhancer looping // inferred from mutant phenotype /// 0071899 // negative regulation of estrogen receptor binding // inferred from mutant phenotype" 0000812 // Swr1 complex // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043141 // ATP-dependent 5'-3' DNA helicase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 201460_at AI141802 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI141802 /FEA=EST /DB_XREF=gi:3649259 /DB_XREF=est:qa56e05.s1 /CLONE=IMAGE:1690784 /UG=Hs.75074 mitogen-activated protein kinase-activated protein kinase 2 /FL=gb:NM_004759.1 gb:U12779.1 AI141802 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 9261 NM_004759 /// NM_032960 /// XM_005273353 0000165 // MAPK cascade // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032675 // regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 201461_s_at NM_004759 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004759.1 /DEF=Homo sapiens mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), mRNA. /FEA=mRNA /GEN=MAPKAPK2 /PROD=mitogen-activated protein kinase-activatedprotein kinase 2 /DB_XREF=gi:10863900 /UG=Hs.75074 mitogen-activated protein kinase-activated protein kinase 2 /FL=gb:NM_004759.1 gb:U12779.1" NM_004759 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 9261 NM_004759 /// NM_032960 /// XM_005273353 0000165 // MAPK cascade // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032675 // regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 201462_at NM_014766 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014766.1 /DEF=Homo sapiens KIAA0193 gene product (KIAA0193), mRNA. /FEA=mRNA /GEN=KIAA0193 /PROD=KIAA0193 gene product /DB_XREF=gi:7661983 /UG=Hs.75137 KIAA0193 gene product /FL=gb:D83777.1 gb:NM_014766.1" NM_014766 secernin 1 SCRN1 9805 NM_001145513 /// NM_001145514 /// NM_001145515 /// NM_014766 /// XM_005249918 0006508 // proteolysis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0016805 // dipeptidase activity // inferred from electronic annotation 201463_s_at NM_006755 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006755.1 /DEF=Homo sapiens transaldolase 1 (TALDO1), mRNA. /FEA=mRNA /GEN=TALDO1 /PROD=transaldolase 1 /DB_XREF=gi:5803186 /UG=Hs.77290 transaldolase 1 /FL=gb:L19437.2 gb:NM_006755.1" NM_006755 transaldolase 1 TALDO1 6888 NM_006755 "0005975 // carbohydrate metabolic process // traceable author statement /// 0005999 // xylulose biosynthetic process // traceable author statement /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0009052 // pentose-phosphate shunt, non-oxidative branch // inferred from electronic annotation /// 0019682 // glyceraldehyde-3-phosphate metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004801 // sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0048029 // monosaccharide binding // inferred from electronic annotation 201464_x_at BG491844 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG491844 /FEA=EST /DB_XREF=gi:13453356 /DB_XREF=est:602535931T1 /CLONE=IMAGE:4684998 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2 BG491844 jun proto-oncogene JUN 3725 NM_002228 "0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation" 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 201465_s_at BC002646 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002646.1 /DEF=Homo sapiens, v-jun avian sarcoma virus 17 oncogene homolog, clone MGC:3338, mRNA, complete cds. /FEA=mRNA /PROD=v-jun avian sarcoma virus 17 oncogene homolog /DB_XREF=gi:12803622 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2" BC002646 jun proto-oncogene JUN 3725 NM_002228 "0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation" 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 201466_s_at NM_002228 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002228.2 /DEF=Homo sapiens v-jun avian sarcoma virus 17 oncogene homolog (JUN), mRNA. /FEA=mRNA /GEN=JUN /PROD=v-jun avian sarcoma virus 17 oncogene homolog /DB_XREF=gi:7710122 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2" NM_002228 jun proto-oncogene JUN 3725 NM_002228 "0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation" 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation 201467_s_at AI039874 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI039874 /FEA=EST /DB_XREF=gi:3279068 /DB_XREF=est:ox97c05.x1 /CLONE=IMAGE:1664264 /UG=Hs.80706 diaphorase (NADHNADPH) (cytochrome b-5 reductase) /FL=gb:J03934.1 gb:NM_000903.1 AI039874 "NAD(P)H dehydrogenase, quinone 1" NQO1 1728 NM_000903 /// NM_001025433 /// NM_001025434 /// NM_001286137 "0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // traceable author statement /// 0004784 // superoxide dismutase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201468_s_at NM_000903 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000903.1 /DEF=Homo sapiens diaphorase (NADHNADPH) (cytochrome b-5 reductase) (DIA4), mRNA. /FEA=mRNA /GEN=DIA4 /PROD=NAD(P)H menadione oxidoreductase 1,dioxin-inducible /DB_XREF=gi:4505414 /UG=Hs.80706 diaphorase (NADHNADPH) (cytochrome b-5 reductase) /FL=gb:J03934.1 gb:NM_000903.1" NM_000903 "NAD(P)H dehydrogenase, quinone 1" NQO1 1728 NM_000903 /// NM_001025433 /// NM_001025434 /// NM_001286137 "0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // traceable author statement /// 0004784 // superoxide dismutase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201469_s_at AI809967 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI809967 /FEA=EST /DB_XREF=gi:5396533 /DB_XREF=est:wf64c03.x1 /CLONE=IMAGE:2360356 /UG=Hs.81972 SHC (Src homology 2 domain-containing) transforming protein 1 /FL=gb:NM_003029.1 gb:U73377.1 AI809967 SHC (Src homology 2 domain containing) transforming protein 1 SHC1 6464 NM_001130040 /// NM_001130041 /// NM_001202859 /// NM_003029 /// NM_183001 /// XM_005245449 /// XM_005245450 /// XM_005245451 /// XM_005245452 0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007176 // regulation of epidermal growth factor-activated receptor activity // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction 201470_at NM_004832 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004832.1 /DEF=Homo sapiens glutathione-S-transferase like; glutathione transferase omega (GSTTLp28), mRNA. /FEA=mRNA /GEN=GSTTLp28 /PROD=glutathione-S-transferase like /DB_XREF=gi:4758483 /UG=Hs.11465 glutathione-S-transferase like; glutathione transferase omega /FL=gb:BC000127.1 gb:U90313.1 gb:NM_004832.1 gb:AF212303.1" NM_004832 glutathione S-transferase omega 1 GSTO1 9446 NM_001191002 /// NM_001191003 /// NM_004832 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from direct assay /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0014810 // positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred by curator /// 0019852 // L-ascorbic acid metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060316 // positive regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0071243 // cellular response to arsenic-containing substance // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0045174 // glutathione dehydrogenase (ascorbate) activity // inferred from direct assay /// 0050610 // methylarsonate reductase activity // inferred from electronic annotation 201471_s_at NM_003900 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003900.1 /DEF=Homo sapiens sequestosome 1 (SQSTM1), mRNA. /FEA=mRNA /GEN=SQSTM1 /PROD=sequestosome 1 /DB_XREF=gi:4505570 /UG=Hs.182248 sequestosome 1 /FL=gb:U41806.1 gb:BC003139.1 gb:U46751.1 gb:NM_003900.1" NM_003900 sequestosome 1 SQSTM1 8878 NM_001142298 /// NM_001142299 /// NM_003900 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006914 // autophagy // inferred from mutant phenotype /// 0006914 // autophagy // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0008104 // protein localization // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0016236 // macroautophagy // inferred from sequence or structural similarity /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046578 // regulation of Ras protein signal transduction // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // traceable author statement /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070530 // K63-linked polyubiquitin binding // inferred from electronic annotation 201472_at NM_003372 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003372.2 /DEF=Homo sapiens von Hippel-Lindau binding protein 1 (VBP1), mRNA. /FEA=mRNA /GEN=VBP1 /PROD=von Hippel-Lindau binding protein 1 /DB_XREF=gi:9257253 /UG=Hs.198307 von Hippel-Lindau binding protein 1 /FL=gb:U96759.1 gb:NM_003372.2" NM_003372 von Hippel-Lindau binding protein 1 VBP1 7411 NM_003372 /// XM_005274729 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016272 // prefoldin complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 201473_at NM_002229 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002229.1 /DEF=Homo sapiens jun B proto-oncogene (JUNB), mRNA. /FEA=mRNA /GEN=JUNB /PROD=jun B proto-oncogene /DB_XREF=gi:4504808 /UG=Hs.198951 jun B proto-oncogene /FL=gb:BC004250.1 gb:NM_002229.1" NM_002229 jun B proto-oncogene JUNB 3726 NM_002229 "0001570 // vasculogenesis // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033687 // osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046697 // decidualization // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation" 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201474_s_at NM_002204 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002204.1 /DEF=Homo sapiens integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant a, mRNA. /FEA=mRNA /GEN=ITGA3 /PROD=integrin alpha 3 isoform a precursor /DB_XREF=gi:4504746 /UG=Hs.265829 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) /FL=gb:M59911.1 gb:NM_002204.1" NM_002204 "integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)" ITGA3 3675 NM_002204 /// NM_005501 /// XM_005257308 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 201475_x_at NM_004990 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004990.1 /DEF=Homo sapiens methionine-tRNA synthetase (MARS), mRNA. /FEA=mRNA /GEN=MARS /PROD=methionine-tRNA synthetase /DB_XREF=gi:4826825 /UG=Hs.279946 methionine-tRNA synthetase /FL=gb:BC002384.1 gb:NM_004990.1 gb:D84224.1" NM_004990 methionyl-tRNA synthetase /// microRNA 6758 MARS /// MIR6758 4141 /// 102465454 NM_004990 /// NR_106816 /// XM_006719398 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006431 // methionyl-tRNA aminoacylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004825 // methionine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201476_s_at AI692974 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI692974 /FEA=EST /DB_XREF=gi:4970314 /DB_XREF=est:wd36e03.x1 /CLONE=IMAGE:2330236 /UG=Hs.2934 ribonucleotide reductase M1 polypeptide /FL=gb:NM_001033.1 AI692974 ribonucleotide reductase M1 RRM1 6240 NM_001033 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005971 // ribonucleoside-diphosphate reductase complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation" 201477_s_at NM_001033 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001033.1 /DEF=Homo sapiens ribonucleotide reductase M1 polypeptide (RRM1), mRNA. /FEA=mRNA /GEN=RRM1 /PROD=ribonucleotide reductase M1 polypeptide /DB_XREF=gi:4506748 /UG=Hs.2934 ribonucleotide reductase M1 polypeptide /FL=gb:NM_001033.1" NM_001033 ribonucleotide reductase M1 RRM1 6240 NM_001033 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005971 // ribonucleoside-diphosphate reductase complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation" 201478_s_at U59151 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U59151.1 /DEF=Human Cbf5p homolog (CBF5) mRNA, complete cds. /FEA=mRNA /GEN=CBF5 /PROD=Cbf5p homolog /DB_XREF=gi:2737893 /UG=Hs.4747 dyskeratosis congenita 1, dyskerin /FL=gb:U59151.1 gb:AF067008.1 gb:NM_001363.1" U59151 "dyskeratosis congenita 1, dyskerin /// microRNA 664b /// small nucleolar RNA, H/ACA box 56" DKC1 /// MIR664B /// SNORA56 1736 /// 677835 /// 100847052 NM_001142463 /// NM_001288747 /// NM_001363 /// NR_002984 /// NR_049842 /// NR_110021 /// NR_110022 /// NR_110023 0000723 // telomere maintenance // traceable author statement /// 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201479_at NM_001363 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001363.1 /DEF=Homo sapiens dyskeratosis congenita 1, dyskerin (DKC1), mRNA. /FEA=mRNA /GEN=DKC1 /PROD=dyskeratosis congenita 1, dyskerin /DB_XREF=gi:4503336 /UG=Hs.4747 dyskeratosis congenita 1, dyskerin /FL=gb:U59151.1 gb:AF067008.1 gb:NM_001363.1" NM_001363 "dyskeratosis congenita 1, dyskerin /// microRNA 664b /// small nucleolar RNA, H/ACA box 56" DKC1 /// MIR664B /// SNORA56 1736 /// 677835 /// 100847052 NM_001142463 /// NM_001288747 /// NM_001363 /// NR_002984 /// NR_049842 /// NR_110021 /// NR_110022 /// NR_110023 0000723 // telomere maintenance // traceable author statement /// 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009451 // RNA modification // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201480_s_at NM_003169 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003169.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 5 homolog (SUPT5H), mRNA. /FEA=mRNA /GEN=SUPT5H /PROD=suppressor of Ty (S.cerevisiae) 5 homolog /DB_XREF=gi:4507312 /UG=Hs.70186 suppressor of Ty (S.cerevisiae) 5 homolog /FL=gb:U56402.1 gb:AB000516.1 gb:NM_003169.1" NM_003169 suppressor of Ty 5 homolog (S. cerevisiae) SUPT5H 6829 NM_001111020 /// NM_001130824 /// NM_001130825 /// NM_003169 /// XM_005259183 /// XM_006723337 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006354 // DNA-templated transcription, elongation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0010033 // response to organic substance // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016239 // positive regulation of macroautophagy // inferred from mutant phenotype /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from electronic annotation /// 0032785 // negative regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0039692 // single stranded viral RNA replication via double stranded DNA intermediate // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0032044 // DSIF complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201481_s_at NM_002862 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002862.1 /DEF=Homo sapiens phosphorylase, glycogen; brain (PYGB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PYGB /PROD=phosphorylase, glycogen; brain /DB_XREF=gi:4506350 /UG=Hs.75658 phosphorylase, glycogen; brain /FL=gb:U47025.1 gb:NM_002862.1" NM_002862 "phosphorylase, glycogen; brain" PYGB 5834 NM_002862 /// XM_006723601 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // non-traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0008184 // glycogen phosphorylase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation" 201482_at NM_002826 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002826.2 /DEF=Homo sapiens quiescin Q6 (QSCN6), mRNA. /FEA=mRNA /GEN=QSCN6 /PROD=quiescin Q6 /DB_XREF=gi:13325074 /UG=Hs.77266 quiescin Q6 /FL=gb:L42379.1 gb:U97276.2 gb:NM_002826.2" NM_002826 quiescin Q6 sulfhydryl oxidase 1 QSOX1 5768 NM_001004128 /// NM_002826 0006457 // protein folding // inferred from direct assay /// 0006457 // protein folding // inferred from genetic interaction /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003756 // protein disulfide isomerase activity // inferred from direct assay /// 0003756 // protein disulfide isomerase activity // inferred from genetic interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016971 // flavin-linked sulfhydryl oxidase activity // inferred from direct assay /// 0016971 // flavin-linked sulfhydryl oxidase activity // inferred from genetic interaction /// 0016972 // thiol oxidase activity // inferred from electronic annotation 201483_s_at BC002802 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002802.1 /DEF=Homo sapiens, suppressor of Ty (S.cerevisiae) 4 homolog 1, clone MGC:3864, mRNA, complete cds. /FEA=mRNA /PROD=suppressor of Ty (S.cerevisiae) 4 homolog 1 /DB_XREF=gi:12803910 /UG=Hs.79058 suppressor of Ty (S.cerevisiae) 4 homolog 1 /FL=gb:BC002802.1 gb:U43923.1 gb:U38818.1 gb:U38817.1 gb:NM_003168.1" BC002802 suppressor of Ty 4 homolog 1 (S. cerevisiae) SUPT4H1 6827 NM_003168 /// NR_073470 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032785 // negative regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032044 // DSIF complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201484_at NM_003168 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003168.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 4 homolog 1 (SUPT4H1), mRNA. /FEA=mRNA /GEN=SUPT4H1 /PROD=suppressor of Ty (S.cerevisiae) 4 homolog 1 /DB_XREF=gi:4507310 /UG=Hs.79058 suppressor of Ty (S.cerevisiae) 4 homolog 1 /FL=gb:BC002802.1 gb:U43923.1 gb:U38818.1 gb:U38817.1 gb:NM_003168.1" NM_003168 suppressor of Ty 4 homolog 1 (S. cerevisiae) SUPT4H1 6827 NM_003168 /// NR_073470 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032785 // negative regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032044 // DSIF complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201485_s_at BC004892 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC004892.1 /DEF=Homo sapiens, reticulocalbin 2, EF-hand calcium binding domain, clone MGC:1650, mRNA, complete cds. /FEA=mRNA /PROD=reticulocalbin 2, EF-hand calcium bindingdomain /DB_XREF=gi:13436151 /UG=Hs.79088 reticulocalbin 2, EF-hand calcium binding domain /FL=gb:BC004892.1 gb:NM_002902.1" BC004892 "reticulocalbin 2, EF-hand calcium binding domain" RCN2 5955 NM_001271837 /// NM_002902 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201486_at NM_002902 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002902.1 /DEF=Homo sapiens reticulocalbin 2, EF-hand calcium binding domain (RCN2), mRNA. /FEA=mRNA /GEN=RCN2 /PROD=reticulocalbin 2, EF-hand calcium bindingdomain /DB_XREF=gi:4506456 /UG=Hs.79088 reticulocalbin 2, EF-hand calcium binding domain /FL=gb:BC004892.1 gb:NM_002902.1" NM_002902 "reticulocalbin 2, EF-hand calcium binding domain" RCN2 5955 NM_001271837 /// NM_002902 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201487_at NM_001814 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001814.1 /DEF=Homo sapiens cathepsin C (CTSC), mRNA. /FEA=mRNA /GEN=CTSC /PROD=cathepsin C /DB_XREF=gi:4503140 /UG=Hs.10029 cathepsin C /FL=gb:NM_001814.1" NM_001814 cathepsin C CTSC 1075 NM_001114173 /// NM_001814 /// NM_148170 0001913 // T cell mediated cytotoxicity // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 1903052 // positive regulation of proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from sequence or structural similarity 201488_x_at BC000717 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000717.1 /DEF=Homo sapiens, GAP-associated tyrosine phosphoprotein p62 (Sam68), clone MGC:1286, mRNA, complete cds. /FEA=mRNA /PROD=GAP-associated tyrosine phosphoprotein p62(Sam68) /DB_XREF=gi:12653852 /UG=Hs.119537 GAP-associated tyrosine phosphoprotein p62 (Sam68) /FL=gb:BC000717.1 gb:M88108.1 gb:NM_006559.1" BC000717 "KH domain containing, RNA binding, signal transduction associated 1" KHDRBS1 10657 NM_001271878 /// NM_006559 /// NR_073498 /// NR_073499 "0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // inferred from physical interaction /// 0031647 // regulation of protein stability // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045948 // positive regulation of translational initiation // inferred from direct assay /// 0046831 // regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0046833 // positive regulation of RNA export from nucleus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070618 // Grb2-Sos complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201489_at BC005020 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005020.1 /DEF=Homo sapiens, peptidylprolyl isomerase F (cyclophilin F), clone MGC:11022, mRNA, complete cds. /FEA=mRNA /PROD=peptidylprolyl isomerase F (cyclophilin F) /DB_XREF=gi:13477126 /UG=Hs.173125 peptidylprolyl isomerase F (cyclophilin F) /FL=gb:BC005020.1 gb:M80254.1 gb:NM_005729.1" BC005020 peptidylprolyl isomerase F PPIF 10105 NM_005729 /// XM_005269379 "0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010849 // regulation of proton-transporting ATPase activity, rotational mechanism // inferred from sequence or structural similarity /// 0010939 // regulation of necrotic cell death // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090324 // negative regulation of oxidative phosphorylation // inferred from sequence or structural similarity /// 1902445 // regulation of mitochondrial membrane permeability involved in programmed necrotic cell death // inferred from mutant phenotype /// 2000276 // negative regulation of oxidative phosphorylation uncoupler activity // inferred from sequence or structural similarity /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 201490_s_at NM_005729 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005729.1 /DEF=Homo sapiens peptidylprolyl isomerase F (cyclophilin F) (PPIF), mRNA. /FEA=mRNA /GEN=PPIF /PROD=peptidylprolyl isomerase F (cyclophilin F) /DB_XREF=gi:5031986 /UG=Hs.173125 peptidylprolyl isomerase F (cyclophilin F) /FL=gb:BC005020.1 gb:M80254.1 gb:NM_005729.1" NM_005729 peptidylprolyl isomerase F PPIF 10105 NM_005729 /// XM_005269379 "0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0010849 // regulation of proton-transporting ATPase activity, rotational mechanism // inferred from sequence or structural similarity /// 0010939 // regulation of necrotic cell death // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0032780 // negative regulation of ATPase activity // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from mutant phenotype /// 0071243 // cellular response to arsenic-containing substance // inferred from sequence or structural similarity /// 0071277 // cellular response to calcium ion // inferred from sequence or structural similarity /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090324 // negative regulation of oxidative phosphorylation // inferred from sequence or structural similarity /// 1902445 // regulation of mitochondrial membrane permeability involved in programmed necrotic cell death // inferred from mutant phenotype /// 2000276 // negative regulation of oxidative phosphorylation uncoupler activity // inferred from sequence or structural similarity /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 201491_at NM_012111 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012111.1 /DEF=Homo sapiens chromosome 14 open reading frame 3 (C14ORF3), mRNA. /FEA=mRNA /GEN=C14ORF3 /PROD=chromosome 14 open reading frame 3 /DB_XREF=gi:6912279 /UG=Hs.204041 chromosome 14 open reading frame 3 /FL=gb:BC000321.1 gb:NM_012111.1 gb:AF164791.1" NM_012111 "AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)" AHSA1 10598 NM_012111 0006457 // protein folding // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0032781 // positive regulation of ATPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from direct assay 201492_s_at NM_021104 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021104.1 /DEF=Homo sapiens ribosomal protein L41 (RPL41), mRNA. /FEA=mRNA /GEN=RPL41 /PROD=ribosomal protein L41 /DB_XREF=gi:10863874 /UG=Hs.324406 ribosomal protein L41 /FL=gb:NM_021104.1" NM_021104 ribosomal protein L41 RPL41 6171 NM_001035267 /// NM_021104 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 201493_s_at BE778078 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE778078 /FEA=EST /DB_XREF=gi:10199276 /DB_XREF=est:601463189F1 /CLONE=IMAGE:3866399 /UG=Hs.6151 pumilio (Drosophila) homolog 2 /FL=gb:AF315591.1 gb:NM_015317.1 BE778078 pumilio RNA-binding family member 2 PUM2 23369 NM_001282752 /// NM_001282790 /// NM_001282791 /// NM_015317 /// XM_005262607 /// XM_005262609 /// XM_005262610 /// XM_006711972 /// XM_006711973 /// XM_006711974 /// XM_006711975 0006417 // regulation of translation // inferred from electronic annotation /// 0034063 // stress granule assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201494_at NM_005040 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005040.1 /DEF=Homo sapiens prolylcarboxypeptidase (angiotensinase C) (PRCP), mRNA. /FEA=mRNA /GEN=PRCP /PROD=prolylcarboxypeptidase (angiotensinase C) /DB_XREF=gi:4826939 /UG=Hs.75693 prolylcarboxypeptidase (angiotensinase C) /FL=gb:L13977.1 gb:NM_005040.1" NM_005040 prolylcarboxypeptidase (angiotensinase C) PRCP 5547 NM_005040 /// NM_199418 /// XM_005274093 "0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement" 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201495_x_at AI889739 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI889739 /FEA=EST /DB_XREF=gi:5594903 /DB_XREF=est:wo17e08.x1 /CLONE=IMAGE:2455622 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1" AI889739 "myosin, heavy chain 11, smooth muscle" MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0051015 // actin filament binding // inferred from electronic annotation 201496_x_at S67238 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:S67238.1 /DEF=smooth muscle myosin heavy chain isoform SM2 human, umbilical cord, fetal aorta, mRNA Partial, 1078 nt. /FEA=mRNA /GEN=smooth muscle myosin heavy chain isoform SM2 /PROD=smooth muscle myosin heavy chain isoform SM2 /DB_XREF=gi:452982 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1" S67238 "myosin, heavy chain 11, smooth muscle" MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0001725 // stress fiber // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0032982 // myosin filament // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0051015 // actin filament binding // inferred from electronic annotation 201497_x_at NM_022844 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022844.1 /DEF=Homo sapiens myosin, heavy polypeptide 11, smooth muscle (MYH11), transcript variant SM2, mRNA. /FEA=mRNA /GEN=MYH11 /PROD=smooth muscle myosin heavy chain 11, isoformSM2 /DB_XREF=gi:13124874 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1" NM_022844 "myosin, heavy chain 11, smooth muscle" MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 "0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030241 // skeletal muscle myosin thick filament assembly // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity" 0001725 // stress fiber // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0032982 // myosin filament // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005159 // insulin-like growth factor receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype /// 0030546 // receptor activator activity // inferred from electronic annotation /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0043539 // protein serine/threonine kinase activator activity // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from electronic annotation 201498_at AI160440 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI160440 /FEA=EST /DB_XREF=gi:3693820 /DB_XREF=est:qc08f12.x1 /CLONE=IMAGE:1709039 /UG=Hs.78683 ubiquitin specific protease 7 (herpes virus-associated) /FL=gb:NM_003470.1 AI160440 ubiquitin specific peptidase 7 (herpes virus-associated) USP7 7874 NM_001286457 /// NM_001286458 /// NM_003470 0006281 // DNA repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0002039 // p53 binding // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 201499_s_at NM_003470 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003470.1 /DEF=Homo sapiens ubiquitin specific protease 7 (herpes virus-associated) (USP7), mRNA. /FEA=mRNA /GEN=USP7 /PROD=ubiquitin specific protease 7 (herpesvirus-associated) /DB_XREF=gi:4507856 /UG=Hs.78683 ubiquitin specific protease 7 (herpes virus-associated) /FL=gb:NM_003470.1" NM_003470 ubiquitin specific peptidase 7 (herpes virus-associated) USP7 7874 NM_001286457 /// NM_001286458 /// NM_003470 0006281 // DNA repair // inferred from electronic annotation /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation 0002039 // p53 binding // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 201500_s_at NM_021959 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021959.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA. /FEA=mRNA /GEN=PPP1R11 /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 11 /DB_XREF=gi:11386174 /UG=Hs.82887 protein phosphatase 1, regulatory (inhibitor) subunit 11 /FL=gb:NM_021959.1" NM_021959 "protein phosphatase 1, regulatory (inhibitor) subunit 11" PPP1R11 6992 NM_021959 /// NM_170781 /// XM_005275158 /// XM_006715174 /// XM_006725042 /// XM_006725499 /// XM_006725713 /// XM_006725921 /// XM_006726016 /// XM_006726110 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201501_s_at NM_002092 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002092.1 /DEF=Homo sapiens G-rich RNA sequence binding factor 1 (GRSF1), mRNA. /FEA=mRNA /GEN=GRSF1 /PROD=G-rich RNA sequence binding factor 1 /DB_XREF=gi:4504160 /UG=Hs.79295 G-rich RNA sequence binding factor 1 /FL=gb:NM_002092.1 gb:U07231.1" NM_002092 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 /// XM_005265681 /// XM_005265685 0006378 // mRNA polyadenylation // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201502_s_at AI078167 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI078167 /FEA=EST /DB_XREF=gi:3412575 /DB_XREF=est:oz30d08.x1 /CLONE=IMAGE:1676847 /UG=Hs.81328 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha /FL=gb:NM_020529.1 gb:BC002601.1 gb:BC004983.1 gb:M69043.1" AI078167 "nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha" NFKBIA 4792 NM_020529 "0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007253 // cytoplasmic sequestering of NF-kappaB // inferred from mutant phenotype /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010875 // positive regulation of cholesterol efflux // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042345 // regulation of NF-kappaB import into nucleus // non-traceable author statement /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0070417 // cellular response to cold // non-traceable author statement /// 0070427 // nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0033256 // I-kappaB/NF-kappaB complex // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0008139 // nuclear localization sequence binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from physical interaction 201503_at BG500067 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG500067 /FEA=EST /DB_XREF=gi:13461584 /DB_XREF=est:602545874F1 /CLONE=IMAGE:4668234 /UG=Hs.220689 Ras-GTPase-activating protein SH3-domain-binding protein /FL=gb:U32519.1 gb:NM_005754.1 BG500067 GTPase activating protein (SH3 domain) binding protein 1 G3BP1 10146 NM_005754 /// NM_198395 /// XM_006714749 /// XM_006714750 0006200 // ATP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201504_s_at AI435302 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI435302 /FEA=EST /DB_XREF=gi:4302230 /DB_XREF=est:ti02h06.x1 /CLONE=IMAGE:2129339 /UG=Hs.75066 translin /FL=gb:NM_004622.1 AI435302 translin TSN 7247 NM_001261401 /// NM_004622 /// NR_048556 /// NR_048557 /// NR_048558 /// NR_048559 0006310 // DNA recombination // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201505_at NM_002291 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002291.1 /DEF=Homo sapiens laminin, beta 1 (LAMB1), mRNA. /FEA=mRNA /GEN=LAMB1 /PROD=laminin, beta 1 precursor /DB_XREF=gi:4504950 /UG=Hs.82124 laminin, beta 1 /FL=gb:M61916.1 gb:NM_002291.1" NM_002291 "laminin, beta 1" LAMB1 3912 NM_002291 0007155 // cell adhesion // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0021812 // neuronal-glial interaction involved in cerebral cortex radial glia guided migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031175 // neuron projection development // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042476 // odontogenesis // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005604 // basement membrane // traceable author statement /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from direct assay /// 0005606 // laminin-1 complex // inferred from physical interaction /// 0005606 // laminin-1 complex // traceable author statement /// 0005607 // laminin-2 complex // inferred from direct assay /// 0005607 // laminin-2 complex // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043256 // laminin complex // inferred from electronic annotation /// 0043257 // laminin-8 complex // inferred from direct assay /// 0043257 // laminin-8 complex // traceable author statement /// 0043259 // laminin-10 complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation 201506_at NM_000358 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000358.1 /DEF=Homo sapiens transforming growth factor, beta-induced, 68kD (TGFBI), mRNA. /FEA=mRNA /GEN=TGFBI /PROD=transforming growth factor, beta-induced, 68kD /DB_XREF=gi:4507466 /UG=Hs.118787 transforming growth factor, beta-induced, 68kD /FL=gb:BC000097.1 gb:BC004972.1 gb:M77349.1 gb:NM_000358.1" NM_000358 "transforming growth factor, beta-induced, 68kDa" TGFBI 7045 NM_000358 0001525 // angiogenesis // inferred from expression pattern /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201507_at NM_002622 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002622.2 /DEF=Homo sapiens prefoldin 1 (PFDN1), mRNA. /FEA=mRNA /GEN=PFDN1 /PROD=prefoldin 1 /DB_XREF=gi:12408673 /UG=Hs.132881 prefoldin 1 /FL=gb:NM_002622.2" NM_002622 prefoldin subunit 1 PFDN1 5201 NM_002622 /// XM_005268465 "0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement" 0016272 // prefoldin complex // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 201508_at NM_001552 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001552.1 /DEF=Homo sapiens insulin-like growth factor-binding protein 4 (IGFBP4), mRNA. /FEA=mRNA /GEN=IGFBP4 /PROD=insulin-like growth factor-binding protein 4 /DB_XREF=gi:10835020 /UG=Hs.1516 insulin-like growth factor-binding protein 4 /FL=gb:NM_001552.1 gb:M62403.1" NM_001552 insulin-like growth factor binding protein 4 IGFBP4 3487 NM_001552 0001501 // skeletal system development // traceable author statement /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201509_at NM_006899 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006899.1 /DEF=Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), mRNA. /FEA=mRNA /GEN=IDH3B /PROD=isocitrate dehydrogenase 3 (NAD+) beta /DB_XREF=gi:5901981 /UG=Hs.155410 isocitrate dehydrogenase 3 (NAD+) beta /FL=gb:BC001960.1 gb:U49283.1 gb:NM_006899.1" NM_006899 isocitrate dehydrogenase 3 (NAD+) beta IDH3B 3420 NM_001258384 /// NM_006899 /// NM_174855 /// NM_174856 /// XM_005260716 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0006103 // 2-oxoglutarate metabolic process // inferred from electronic annotation /// 0006734 // NADH metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement "0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201510_at AF017307 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF017307.1 /DEF=Homo sapiens Ets-related transcription factor (ERT) mRNA, complete cds. /FEA=mRNA /GEN=ERT /PROD=Ets-related transcription factor /DB_XREF=gi:2338755 /UG=Hs.166096 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) /FL=gb:BC003569.1 gb:U66894.1 gb:U73843.1 gb:AF017307.1 gb:AF016295.1 gb:U97156.1 gb:NM_004433.1" AF017307 "E74-like factor 3 (ets domain transcription factor, epithelial-specific )" ELF3 1999 NM_001114309 /// NM_004433 /// XM_005244942 "0001824 // blastocyst development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // inferred from expression pattern /// 0007275 // multicellular organismal development // traceable author statement /// 0008544 // epidermis development // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from sequence or structural similarity" 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201511_at NM_001087 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001087.1 /DEF=Homo sapiens angio-associated, migratory cell protein (AAMP), mRNA. /FEA=mRNA /GEN=AAMP /PROD=angio-associated, migratory cell protein /DB_XREF=gi:4557228 /UG=Hs.83347 angio-associated, migratory cell protein /FL=gb:NM_001087.1 gb:M95627.1" NM_001087 "angio-associated, migratory cell protein" AAMP 14 NM_001087 /// XM_005246325 0001525 // angiogenesis // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from sequence or structural similarity /// 0014909 // smooth muscle cell migration // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // traceable author statement 201512_s_at BC003633 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003633.1 /DEF=Homo sapiens, translocase of outer mitochondrial membrane 70 (yeast) homolog A, clone MGC:3766, mRNA, complete cds. /FEA=mRNA /PROD=translocase of outer mitochondrial membrane 70(yeast) homolog A /DB_XREF=gi:13177705 /UG=Hs.21198 translocase of outer mitochondrial membrane 70 (yeast) homolog A /FL=gb:BC003633.1 gb:AB018262.1 gb:NM_014820.1" BC003633 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) TOMM70A 9868 NM_014820 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201513_at AI659180 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI659180 /FEA=EST /DB_XREF=gi:4762750 /DB_XREF=est:tu02c06.x1 /CLONE=IMAGE:2249866 /UG=Hs.75066 translin /FL=gb:NM_004622.1 AI659180 translin TSN 7247 NM_001261401 /// NM_004622 /// NR_048556 /// NR_048557 /// NR_048558 /// NR_048559 0006310 // DNA recombination // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201514_s_at NM_005754 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005754.1 /DEF=Homo sapiens Ras-GTPase-activating protein SH3-domain-binding protein (G3BP), mRNA. /FEA=mRNA /GEN=G3BP /PROD=Ras-GTPase-activating protein SH3-domain-bindingprotein /DB_XREF=gi:5031702 /UG=Hs.220689 Ras-GTPase-activating protein SH3-domain-binding protein /FL=gb:U32519.1 gb:NM_005754.1" NM_005754 GTPase activating protein (SH3 domain) binding protein 1 G3BP1 10146 NM_005754 /// NM_198395 /// XM_006714749 /// XM_006714750 0006200 // ATP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201515_s_at NM_004622 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004622.1 /DEF=Homo sapiens translin (TSN), mRNA. /FEA=mRNA /GEN=TSN /PROD=translin /DB_XREF=gi:4759269 /UG=Hs.75066 translin /FL=gb:NM_004622.1" NM_004622 translin TSN 7247 NM_001261401 /// NM_004622 /// NR_048556 /// NR_048557 /// NR_048558 /// NR_048559 0006310 // DNA recombination // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201516_at NM_003132 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003132.1 /DEF=Homo sapiens spermidine synthase (SRM), mRNA. /FEA=mRNA /GEN=SRM /PROD=spermidine synthase /DB_XREF=gi:4507208 /UG=Hs.76244 spermidine synthase /FL=gb:BC000309.1 gb:NM_003132.1 gb:M34338.1" NM_003132 spermidine synthase SRM 6723 NM_003132 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // inferred from direct assay /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004766 // spermidine synthase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 201517_at BC001255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001255.1 /DEF=Homo sapiens, nuclear cap binding protein subunit 2, 20kD, clone MGC:4991, mRNA, complete cds. /FEA=mRNA /PROD=nuclear cap binding protein subunit 2, 20kD /DB_XREF=gi:12654824 /UG=Hs.240770 nuclear cap binding protein subunit 2, 20kD /FL=gb:D59253.1 gb:BC001255.1 gb:NM_007362.1" BC001255 "nuclear cap binding protein subunit 2, 20kDa" NCBP2 22916 NM_001042540 /// NM_007362 /// XM_005269313 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006408 // snRNA export from nucleus // inferred from sequence or structural similarity /// 0006408 // snRNA export from nucleus // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay /// 0046833 // positive regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0005846 // nuclear cap binding complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // non-traceable author statement /// 0000340 // RNA 7-methylguanosine cap binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201518_at NM_006807 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006807.1 /DEF=Homo sapiens chromobox homolog 1 (Drosophila HP1 beta) (CBX1), mRNA. /FEA=mRNA /GEN=CBX1 /PROD=chromobox homolog 1 (Drosophila HP1 beta) /DB_XREF=gi:5803075 /UG=Hs.77254 chromobox homolog 1 (Drosophila HP1 beta) /FL=gb:U35451.1 gb:BC002609.1 gb:NM_006807.1" NM_006807 chromobox homolog 1 CBX1 10951 NM_001127228 /// NM_006807 "0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation" "0000775 // chromosome, centromeric region // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation" 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 1990226 // histone methyltransferase binding // inferred from physical interaction 201519_at NM_014820 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014820.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 70 (yeast) homolog A (TOMM70A), mRNA. /FEA=mRNA /GEN=TOMM70A /PROD=translocase of outer mitochondrial membrane 70(yeast) homolog A /DB_XREF=gi:7662672 /UG=Hs.21198 translocase of outer mitochondrial membrane 70 (yeast) homolog A /FL=gb:BC003633.1 gb:AB018262.1 gb:NM_014820.1" NM_014820 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) TOMM70A 9868 NM_014820 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201520_s_at BF034561 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF034561 /FEA=EST /DB_XREF=gi:10742273 /DB_XREF=est:601455476F1 /CLONE=IMAGE:3859242 /UG=Hs.79295 G-rich RNA sequence binding factor 1 /FL=gb:NM_002092.1 gb:U07231.1 BF034561 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 /// XM_005265681 /// XM_005265685 0006378 // mRNA polyadenylation // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201521_s_at NM_007362 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007362.1 /DEF=Homo sapiens nuclear cap binding protein subunit 2, 20kD (NCBP2), mRNA. /FEA=mRNA /GEN=NCBP2 /PROD=nuclear cap binding protein subunit 2, 20kD /DB_XREF=gi:6679063 /UG=Hs.240770 nuclear cap binding protein subunit 2, 20kD /FL=gb:D59253.1 gb:BC001255.1 gb:NM_007362.1" NM_007362 "nuclear cap binding protein subunit 2, 20kDa" NCBP2 22916 NM_001042540 /// NM_007362 /// XM_005269313 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from direct assay /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006408 // snRNA export from nucleus // inferred from sequence or structural similarity /// 0006408 // snRNA export from nucleus // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay /// 0046833 // positive regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0005846 // nuclear cap binding complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // non-traceable author statement /// 0000340 // RNA 7-methylguanosine cap binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201522_x_at NM_003097 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003097.2 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA. /FEA=mRNA /GEN=SNRPN /PROD=small nuclear ribonucleoprotein polypeptide N /DB_XREF=gi:13027651 /UG=Hs.48375 small nuclear ribonucleoprotein polypeptide N /FL=gb:U41303.1 gb:NM_003097.2 gb:BC003180.1 gb:J04615.1" NM_003097 small nuclear ribonucleoprotein polypeptide N /// SNRPN upstream reading frame SNRPN /// SNURF 6638 /// 8926 NM_003097 /// NM_005678 /// NM_022804 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 0008380 // RNA splicing // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005686 // U2 snRNP // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201523_x_at BE262760 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE262760 /FEA=EST /DB_XREF=gi:9136144 /DB_XREF=est:601153762F1 /CLONE=IMAGE:3509895 /UG=Hs.75355 ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) /FL=gb:D83004.1 gb:BC000396.1 gb:BC003365.1 gb:NM_003348.1 BE262760 ubiquitin-conjugating enzyme E2N UBE2N 7334 NM_003348 "0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0016574 // histone ubiquitination // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031058 // positive regulation of histone modification // inferred from mutant phenotype /// 0033182 // regulation of histone ubiquitination // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay" 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201524_x_at NM_003348 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003348.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) (UBE2N), mRNA. /FEA=mRNA /GEN=UBE2N /PROD=ubiquitin-conjugating enzyme E2N (homologous toyeast UBC13) /DB_XREF=gi:4507792 /UG=Hs.75355 ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) /FL=gb:D83004.1 gb:BC000396.1 gb:BC003365.1 gb:NM_003348.1" NM_003348 ubiquitin-conjugating enzyme E2N UBE2N 7334 NM_003348 "0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0016574 // histone ubiquitination // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031058 // positive regulation of histone modification // inferred from mutant phenotype /// 0033182 // regulation of histone ubiquitination // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay" 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay /// 0035370 // UBC13-UEV1A complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201525_at NM_001647 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001647.1 /DEF=Homo sapiens apolipoprotein D (APOD), mRNA. /FEA=mRNA /GEN=APOD /PROD=apolipoprotein D precursor /DB_XREF=gi:4502162 /UG=Hs.75736 apolipoprotein D /FL=gb:J02611.1 gb:NM_001647.1" NM_001647 apolipoprotein D APOD 347 NM_001647 0000302 // response to reactive oxygen species // inferred from direct assay /// 0001525 // angiogenesis // non-traceable author statement /// 0006006 // glucose metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // non-traceable author statement /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007568 // aging // non-traceable author statement /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0014012 // peripheral nervous system axon regeneration // inferred from sequence or structural similarity /// 0030682 // evasion or tolerance of host defense response // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from sequence or structural similarity /// 0042308 // negative regulation of protein import into nucleus // inferred from direct assay /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0060588 // negative regulation of lipoprotein lipid oxidation // inferred from direct assay /// 0071638 // negative regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 1900016 // negative regulation of cytokine production involved in inflammatory response // inferred from direct assay /// 2000098 // negative regulation of smooth muscle cell-matrix adhesion // inferred from mutant phenotype /// 2000405 // negative regulation of T cell migration // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0022626 // cytosolic ribosome // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0036094 // small molecule binding // inferred from electronic annotation 201526_at NM_001662 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001662.2 /DEF=Homo sapiens ADP-ribosylation factor 5 (ARF5), mRNA. /FEA=mRNA /GEN=ARF5 /PROD=ADP-ribosylation factor 5 /DB_XREF=gi:6995999 /UG=Hs.77541 ADP-ribosylation factor 5 /FL=gb:BC003043.1 gb:M57567.1 gb:NM_001662.2" NM_001662 ADP-ribosylation factor 5 ARF5 381 NM_001662 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201527_at NM_004231 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004231.1 /DEF=Homo sapiens ATPase, vacuolar, 14 kD (ATP6S14), mRNA. /FEA=mRNA /GEN=ATP6S14 /PROD=ATPase, vacuolar, 14 kD /DB_XREF=gi:4757819 /UG=Hs.78089 ATPase, vacuolar, 14 kD /FL=gb:D49400.1 gb:NM_004231.1" NM_004231 "ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F /// V-type proton ATPase subunit F-like" ATP6V1F /// LOC101927180 9296 /// 101927180 NM_001198909 /// NM_004231 /// XM_005269262 /// XM_005275720 /// XM_005276420 0006200 // ATP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016469 // proton-transporting two-sector ATPase complex // non-traceable author statement /// 0016471 // vacuolar proton-transporting V-type ATPase complex // inferred from direct assay /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0005515 // protein binding // inferred from physical interaction /// 0015078 // hydrogen ion transmembrane transporter activity // non-traceable author statement /// 0042624 // ATPase activity, uncoupled // non-traceable author statement /// 0042625 // ATPase activity, coupled to transmembrane movement of ions // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation" 201528_at BG398414 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG398414 /FEA=EST /DB_XREF=gi:13291862 /DB_XREF=est:602439888F1 /CLONE=IMAGE:4566380 /UG=Hs.84318 replication protein A1 (70kD) /FL=gb:M63488.1 gb:NM_002945.1 BG398414 "replication protein A1, 70kDa" RPA1 6117 NM_002945 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation" 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201529_s_at NM_002945 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002945.1 /DEF=Homo sapiens replication protein A1 (70kD) (RPA1), mRNA. /FEA=mRNA /GEN=RPA1 /PROD=replication protein A1 (70kD) /DB_XREF=gi:4506582 /UG=Hs.84318 replication protein A1 (70kD) /FL=gb:M63488.1 gb:NM_002945.1" NM_002945 "replication protein A1, 70kDa" RPA1 6117 NM_002945 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation" 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000800 // lateral element // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201530_x_at NM_001416 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001416.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA. /FEA=mRNA /GEN=EIF4A1 /PROD=eukaryotic translation initiation factor 4A,isoform 1 /DB_XREF=gi:4503528 /UG=Hs.129673 eukaryotic translation initiation factor 4A, isoform 1 /FL=gb:NM_001416.1" NM_001416 "eukaryotic translation initiation factor 4A1 /// uncharacterized LOC101928634 /// SENP3-EIF4A1 readthrough (NMD candidate) /// small nucleolar RNA, H/ACA box 48 /// small nucleolar RNA, H/ACA box 67 /// small nucleolar RNA, C/D box 10" EIF4A1 /// LOC101928634 /// SENP3-EIF4A1 /// SNORA48 /// SNORA67 /// SNORD10 1973 /// 26781 /// 652965 /// 652966 /// 100533955 /// 101928634 NM_001204510 /// NM_001416 /// NR_002604 /// NR_002912 /// NR_002918 /// NR_037926 /// XR_244579 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement" 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201531_at NM_003407 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003407.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp-36 in mouse (ZFP36), mRNA. /FEA=mRNA /GEN=ZFP36 /PROD=zinc finger protein homologous to Zfp-36 inmouse /DB_XREF=gi:4507960 /UG=Hs.1665 zinc finger protein homologous to Zfp-36 in mouse /FL=gb:M92843.1 gb:M63625.1 gb:NM_003407.1" NM_003407 ZFP36 ring finger protein ZFP36 7538 NM_003407 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from direct assay /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0042594 // response to starvation // inferred from direct assay /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050779 // RNA destabilization // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay /// 0017091 // AU-rich element binding // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019957 // C-C chemokine binding // inferred from physical interaction /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201532_at NM_002788 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002788.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), mRNA. /FEA=mRNA /GEN=PSMA3 /PROD=proteasome (prosome, macropain) subunit, alphatype, 3 /DB_XREF=gi:4506182 /UG=Hs.167106 proteasome (prosome, macropain) subunit, alpha type, 3 /FL=gb:BC005265.1 gb:NM_002788.1" NM_002788 "proteasome (prosome, macropain) subunit, alpha type, 3" PSMA3 5684 NM_002788 /// NM_152132 /// NR_038123 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" "0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from direct assay /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201533_at NM_001904 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001904.1 /DEF=Homo sapiens catenin (cadherin-associated protein), beta 1 (88kD) (CTNNB1), mRNA. /FEA=mRNA /GEN=CTNNB1 /PROD=catenin (cadherin-associated protein), beta 1(88kD) /DB_XREF=gi:4503130 /UG=Hs.171271 catenin (cadherin-associated protein), beta 1 (88kD) /FL=gb:NM_001904.1" NM_001904 "catenin (cadherin-associated protein), beta 1, 88kDa" CTNNB1 1499 NM_001098209 /// NM_001098210 /// NM_001904 /// XM_005264886 /// XM_006712983 /// XM_006712984 /// XM_006712985 "0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000578 // embryonic axis specification // not recorded /// 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001569 // patterning of blood vessels // not recorded /// 0001569 // patterning of blood vessels // inferred by curator /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // not recorded /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001709 // cell fate determination // inferred from electronic annotation /// 0001711 // endodermal cell fate commitment // not recorded /// 0001764 // neuron migration // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0001840 // neural plate development // inferred from electronic annotation /// 0001889 // liver development // not recorded /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003136 // negative regulation of heart induction by canonical Wnt signaling pathway // not recorded /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from electronic annotation /// 0003337 // mesenchymal to epithelial transition involved in metanephros morphogenesis // not recorded /// 0003338 // metanephros morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007016 // cytoskeletal anchoring at plasma membrane // not recorded /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007160 // cell-matrix adhesion // not recorded /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007398 // ectoderm development // not recorded /// 0007403 // glial cell fate determination // not recorded /// 0007494 // midgut development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009725 // response to hormone // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0009950 // dorsal/ventral axis specification // not recorded /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // not recorded /// 0009987 // cellular process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from genetic interaction /// 0010909 // positive regulation of heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0014010 // Schwann cell proliferation // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0022009 // central nervous system vasculogenesis // not recorded /// 0022405 // hair cycle process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // not recorded /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0030539 // male genitalia development // not recorded /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030902 // hindbrain development // not recorded /// 0030997 // regulation of centriole-centriole cohesion // inferred from direct assay /// 0031016 // pancreas development // not recorded /// 0031069 // hair follicle morphogenesis // not recorded /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // not recorded /// 0032355 // response to estradiol // inferred from direct assay /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0033077 // T cell differentiation in thymus // not recorded /// 0033234 // negative regulation of protein sumoylation // inferred from direct assay /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034333 // adherens junction assembly // inferred from mutant phenotype /// 0034394 // protein localization to cell surface // inferred from mutant phenotype /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035112 // genitalia morphogenesis // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035315 // hair cell differentiation // traceable author statement /// 0036023 // embryonic skeletal limb joint morphogenesis // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042129 // regulation of T cell proliferation // not recorded /// 0042475 // odontogenesis of dentin-containing tooth // not recorded /// 0042493 // response to drug // inferred from expression pattern /// 0042692 // muscle cell differentiation // traceable author statement /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // not recorded /// 0043410 // positive regulation of MAPK cascade // not recorded /// 0043587 // tongue morphogenesis // not recorded /// 0043588 // skin development // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044334 // canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // not recorded /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // not recorded /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // not recorded /// 0045765 // regulation of angiogenesis // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048145 // regulation of fibroblast proliferation // traceable author statement /// 0048262 // determination of dorsal/ventral asymmetry // not recorded /// 0048469 // cell maturation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // not recorded /// 0048513 // organ development // inferred from electronic annotation /// 0048538 // thymus development // not recorded /// 0048599 // oocyte development // not recorded /// 0048617 // embryonic foregut morphogenesis // not recorded /// 0048660 // regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050808 // synapse organization // not recorded /// 0051145 // smooth muscle cell differentiation // not recorded /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0060066 // oviduct development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060173 // limb development // inferred from electronic annotation /// 0060439 // trachea morphogenesis // inferred from electronic annotation /// 0060440 // trachea formation // not recorded /// 0060441 // epithelial tube branching involved in lung morphogenesis // inferred from electronic annotation /// 0060479 // lung cell differentiation // not recorded /// 0060484 // lung-associated mesenchyme development // not recorded /// 0060492 // lung induction // not recorded /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0060769 // positive regulation of epithelial cell proliferation involved in prostate gland development // not recorded /// 0060789 // hair follicle placode formation // not recorded /// 0060916 // mesenchymal cell proliferation involved in lung development // not recorded /// 0061047 // positive regulation of branching involved in lung morphogenesis // not recorded /// 0061154 // endothelial tube morphogenesis // inferred from mutant phenotype /// 0061198 // fungiform papilla formation // inferred from electronic annotation /// 0061324 // canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation // inferred from sequence or structural similarity /// 0070602 // regulation of centromeric sister chromatid cohesion // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0072001 // renal system development // inferred from electronic annotation /// 0072033 // renal vesicle formation // not recorded /// 0072053 // renal inner medulla development // not recorded /// 0072054 // renal outer medulla development // not recorded /// 0072079 // nephron tubule formation // not recorded /// 0072182 // regulation of nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 0090279 // regulation of calcium ion import // inferred from direct assay /// 2000008 // regulation of protein localization to cell surface // inferred from direct assay /// 2000017 // positive regulation of determination of dorsal identity // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation" 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005915 // zonula adherens // not recorded /// 0005916 // fascia adherens // not recorded /// 0005924 // cell-substrate adherens junction // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // not recorded /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0016342 // catenin complex // inferred from direct assay /// 0030018 // Z disc // not recorded /// 0030027 // lamellipodium // not recorded /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // traceable author statement /// 0030057 // desmosome // not recorded /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // not recorded /// 0032993 // protein-DNA complex // inferred from direct assay /// 0034750 // Scrib-APC-beta-catenin complex // inferred from electronic annotation /// 0043198 // dendritic shaft // not recorded /// 0043234 // protein complex // inferred from electronic annotation /// 0043296 // apical junction complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // not recorded /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070369 // beta-catenin-TCF7L2 complex // inferred from direct assay /// 0071664 // catenin-TCF7L2 complex // inferred from electronic annotation /// 0071944 // cell periphery // inferred from direct assay 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004871 // signal transducer activity // non-traceable author statement /// 0005198 // structural molecule activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035255 // ionotropic glutamate receptor binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044325 // ion channel binding // inferred from physical interaction /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from electronic annotation 201534_s_at AF044221 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF044221.1 /DEF=Homo sapiens HCG-1 protein (HCG-1) mRNA, complete cds. /FEA=mRNA /GEN=HCG-1 /PROD=HCG-1 protein /DB_XREF=gi:4105251 /UG=Hs.173091 ubiquitin-like 3 /FL=gb:AF044221.1 gb:AL080177.1 gb:NM_007106.1" AF044221 ubiquitin-like 3 UBL3 5412 NM_007106 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201535_at NM_007106 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007106.1 /DEF=Homo sapiens ubiquitin-like 3 (UBL3), mRNA. /FEA=mRNA /GEN=UBL3 /PROD=ubiquitin-like 3 /DB_XREF=gi:6005927 /UG=Hs.173091 ubiquitin-like 3 /FL=gb:AF044221.1 gb:AL080177.1 gb:NM_007106.1" NM_007106 ubiquitin-like 3 UBL3 5412 NM_007106 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201536_at AL048503 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL048503 /FEA=EST /DB_XREF=gi:5936534 /DB_XREF=est:DKFZp586M1524_s1 /CLONE=DKFZp586M1524 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1 AL048503 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0000188 // inactivation of MAPK activity // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from mutant phenotype 201537_s_at BC002682 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002682.1 /DEF=Homo sapiens, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related), clone MGC:3615, mRNA, complete cds. /FEA=mRNA /PROD=dual specificity phosphatase 3 (vaccinia virusphosphatase VH1-related) /DB_XREF=gi:12803692 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1" BC002682 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0000188 // inactivation of MAPK activity // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from mutant phenotype 201538_s_at NM_004090 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004090.1 /DEF=Homo sapiens dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (DUSP3), mRNA. /FEA=mRNA /GEN=DUSP3 /PROD=dual specificity phosphatase 3 /DB_XREF=gi:4758207 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1" NM_004090 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0000188 // inactivation of MAPK activity // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from direct assay /// 0050868 // negative regulation of T cell activation // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from direct assay /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0033549 // MAP kinase phosphatase activity // inferred from mutant phenotype 201539_s_at U29538 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U29538.1 /DEF=Human heart protein with four and a half LIM domains (FHL-1) mRNA, complete cds. /FEA=mRNA /GEN=FHL-1 /DB_XREF=gi:2078479 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:U29538.1 gb:U60115.1 gb:NM_001449.1" U29538 four and a half LIM domains 1 FHL1 2273 NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201540_at NM_001449 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001449.1 /DEF=Homo sapiens four and a half LIM domains 1 (FHL1), mRNA. /FEA=mRNA /GEN=FHL1 /PROD=four and a half LIM domains 1 /DB_XREF=gi:4503720 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:U29538.1 gb:U60115.1 gb:NM_001449.1" NM_001449 four and a half LIM domains 1 FHL1 2273 NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747 0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201541_s_at NM_006349 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006349.1 /DEF=Homo sapiens putative cyclin G1 interacting protein (CG1I), mRNA. /FEA=mRNA /GEN=CG1I /PROD=putative cyclin G1 interacting protein /DB_XREF=gi:5453616 /UG=Hs.10028 putative cyclin G1 interacting protein /FL=gb:U61837.1 gb:NM_006349.1" NM_006349 "zinc finger, HIT-type containing 1" ZNHIT1 10467 NM_006349 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0031063 // regulation of histone deacetylation // inferred from electronic annotation /// 0042129 // regulation of T cell proliferation // inferred from electronic annotation /// 0070317 // negative regulation of G0 to G1 transition // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201542_at AY008268 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AY008268.1 /DEF=Homo sapiens GTP-binding protein SAR1 (SAR1) mRNA, complete cds. /FEA=mRNA /GEN=SAR1 /PROD=GTP-binding protein SAR1 /DB_XREF=gi:10445220 /UG=Hs.110796 SAR1 protein /FL=gb:AY008268.1 gb:AL136724.1 gb:AF261717.1 gb:NM_020150.1" AY008268 "secretion associated, Ras related GTPase 1A" SAR1A 56681 NM_001142648 /// NM_020150 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201543_s_at NM_020150 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020150.1 /DEF=Homo sapiens SAR1 protein (SAR1), mRNA. /FEA=mRNA /GEN=SAR1 /PROD=SAR1 protein /DB_XREF=gi:9910541 /UG=Hs.110796 SAR1 protein /FL=gb:AY008268.1 gb:AL136724.1 gb:AF261717.1 gb:NM_020150.1" NM_020150 "secretion associated, Ras related GTPase 1A" SAR1A 56681 NM_001142648 /// NM_020150 0006184 // GTP catabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 201544_x_at BF675004 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF675004 /FEA=EST /DB_XREF=gi:11948899 /DB_XREF=est:602138088F1 /CLONE=IMAGE:4274564 /UG=Hs.117176 poly(A)-binding protein, nuclear 1 /FL=gb:NM_004643.1" BF675004 "BCL2-like 2 /// BCL2L2-PABPN1 readthrough /// poly(A) binding protein, nuclear 1" BCL2L2 /// BCL2L2-PABPN1 /// PABPN1 599 /// 8106 /// 100529063 NM_001199839 /// NM_001199864 /// NM_004050 /// NM_004643 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0010467 // gene expression // traceable author statement /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0046778 // modification by virus of host mRNA processing // traceable author statement /// 0060011 // Sertoli cell proliferation // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // not recorded" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // not recorded /// 0051400 // BH domain binding // inferred from electronic annotation 201545_s_at NM_004643 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004643.1 /DEF=Homo sapiens poly(A)-binding protein, nuclear 1 (PABPN1), mRNA. /FEA=mRNA /GEN=PABPN1 /PROD=poly(A)-binding protein, nuclear 1 /DB_XREF=gi:4758875 /UG=Hs.117176 poly(A)-binding protein, nuclear 1 /FL=gb:NM_004643.1" NM_004643 "BCL2L2-PABPN1 readthrough /// poly(A) binding protein, nuclear 1" BCL2L2-PABPN1 /// PABPN1 8106 /// 100529063 NM_001199864 /// NM_004643 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0046778 // modification by virus of host mRNA processing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201546_at NM_004238 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004238.1 /DEF=Homo sapiens thyroid hormone receptor interactor 12 (TRIP12), mRNA. /FEA=mRNA /GEN=TRIP12 /PROD=thyroid hormone receptor interactor 12 /DB_XREF=gi:10863902 /UG=Hs.138617 thyroid hormone receptor interactor 12 /FL=gb:NM_004238.1 gb:D28476.1" NM_004238 thyroid hormone receptor interactor 12 TRIP12 9320 NM_001284214 /// NM_001284215 /// NM_001284216 /// NM_004238 /// XM_005246954 /// XM_005246955 /// XM_005246956 /// XM_005246957 /// XM_005246958 /// XM_005246960 /// XM_005246961 /// XM_005246962 /// XM_005246963 /// XM_006712852 /// XM_006712853 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 1901315 // negative regulation of histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 2000780 // negative regulation of double-strand break repair // inferred from mutant phenotype 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // not recorded 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 201547_at AA729218 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA729218 /FEA=EST /DB_XREF=gi:2750577 /DB_XREF=est:nx35a04.s1 /CLONE=IMAGE:1258062 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 AA729218 lysine (K)-specific demethylase 5B KDM5B 10765 NM_006618 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0034721 // histone H3-K4 demethylation, trimethyl-H3-K4-specific // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from electronic annotation /// 0034647 // histone demethylase activity (H3-trimethyl-K4 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 201548_s_at W02593 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:W02593 /FEA=EST /DB_XREF=gi:1274571 /DB_XREF=est:za51e06.r1 /CLONE=IMAGE:296098 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 W02593 lysine (K)-specific demethylase 5B KDM5B 10765 NM_006618 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0034721 // histone H3-K4 demethylation, trimethyl-H3-K4-specific // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from electronic annotation /// 0034647 // histone demethylase activity (H3-trimethyl-K4 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 201549_x_at NM_006618 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006618.1 /DEF=Homo sapiens putative DNAchromatin binding motif (PLU-1), mRNA. /FEA=mRNA /GEN=PLU-1 /PROD=putative DNAchromatin binding motif /DB_XREF=gi:5729977 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1" NM_006618 lysine (K)-specific demethylase 5B KDM5B 10765 NM_006618 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0034721 // histone H3-K4 demethylation, trimethyl-H3-K4-specific // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from electronic annotation /// 0034647 // histone demethylase activity (H3-trimethyl-K4 specific) // inferred from direct assay /// 0034648 // histone demethylase activity (H3-dimethyl-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 201550_x_at NM_001614 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001614.2 /DEF=Homo sapiens actin, gamma 1 (ACTG1), mRNA. /FEA=mRNA /GEN=ACTG1 /PROD=actin, gamma 1 propeptide /DB_XREF=gi:11038618 /UG=Hs.14376 actin, gamma 1 /FL=gb:NM_001614.2 gb:BC000292.1" NM_001614 "actin, beta /// actin, gamma 1" ACTB /// ACTG1 60 /// 71 NM_001101 /// NM_001199954 /// NM_001614 /// NR_037688 /// XM_006715764 /// XM_006722048 /// XM_006722049 0001895 // retina homeostasis // inferred from expression pattern /// 0006325 // chromatin organization // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000790 // nuclear chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019894 // kinesin binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030957 // Tat protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 201551_s_at J03263 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J03263.1 /DEF=Human lysosome-associated membrane glycoprotein (lamp A) mRNA, complete cds. /FEA=mRNA /GEN=LAMP1 /DB_XREF=gi:187178 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2" J03263 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0006914 // autophagy // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0072594 // establishment of protein localization to organelle // inferred from mutant phenotype /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201552_at NM_005561 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005561.2 /DEF=Homo sapiens lysosomal-associated membrane protein 1 (LAMP1), mRNA. /FEA=mRNA /GEN=LAMP1 /PROD=lysosomal-associated membrane protein 1 /DB_XREF=gi:7669500 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2" NM_005561 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0006914 // autophagy // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0072594 // establishment of protein localization to organelle // inferred from mutant phenotype /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201553_s_at NM_005561 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005561.2 /DEF=Homo sapiens lysosomal-associated membrane protein 1 (LAMP1), mRNA. /FEA=mRNA /GEN=LAMP1 /PROD=lysosomal-associated membrane protein 1 /DB_XREF=gi:7669500 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2" NM_005561 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0006914 // autophagy // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0072594 // establishment of protein localization to organelle // inferred from mutant phenotype /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype /// 1902513 // regulation of organelle transport along microtubule // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0044194 // cytolytic granule // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201554_x_at NM_004130 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004130.1 /DEF=Homo sapiens glycogenin (GYG), mRNA. /FEA=mRNA /GEN=GYG /PROD=glycogenin /DB_XREF=gi:4758491 /UG=Hs.174071 glycogenin /FL=gb:U44131.1 gb:BC000033.1 gb:NM_004130.1 gb:U31525.1" NM_004130 glycogenin 1 GYG1 2992 NM_001184720 /// NM_001184721 /// NM_004130 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from electronic annotation /// 0008466 // glycogenin glucosyltransferase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201555_at NM_002388 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002388.2 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 3 (MCM3), mRNA. /FEA=mRNA /GEN=MCM3 /PROD=minichromosome maintenance deficient (S.cerevisiae) 3 /DB_XREF=gi:6631094 /UG=Hs.179565 minichromosome maintenance deficient (S. cerevisiae) 3 /FL=gb:BC001626.1 gb:NM_002388.2 gb:D38073.1" NM_002388 minichromosome maintenance complex component 3 MCM3 4172 NM_001270472 /// NM_002388 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005658 // alpha DNA polymerase:primase complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201556_s_at BC002737 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002737.1 /DEF=Homo sapiens, vesicle-associated membrane protein 2, clone MGC:3377, mRNA, complete cds. /FEA=mRNA /PROD=vesicle-associated membrane protein 2 /DB_XREF=gi:12803794 /UG=Hs.194534 vesicle-associated membrane protein 2 (synaptobrevin 2) /FL=gb:BC002737.1 gb:NM_014232.1" BC002737 vesicle-associated membrane protein 2 (synaptobrevin 2) VAMP2 6844 NM_014232 /// XM_005256775 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0060627 // regulation of vesicle-mediated transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030667 // secretory granule membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000149 // SNARE binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // not recorded /// 0032403 // protein complex binding // inferred from electronic annotation 201557_at NM_014232 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014232.1 /DEF=Homo sapiens vesicle-associated membrane protein 2 (synaptobrevin 2) (VAMP2), mRNA. /FEA=mRNA /GEN=VAMP2 /PROD=vesicle-associated membrane protein 2(synaptobrevin 2) /DB_XREF=gi:7657674 /UG=Hs.194534 vesicle-associated membrane protein 2 (synaptobrevin 2) /FL=gb:BC002737.1 gb:NM_014232.1" NM_014232 vesicle-associated membrane protein 2 (synaptobrevin 2) VAMP2 6844 NM_014232 /// XM_005256775 0006112 // energy reserve metabolic process // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006906 // vesicle fusion // not recorded /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // not recorded /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0060627 // regulation of vesicle-mediated transport // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0090316 // positive regulation of intracellular protein transport // inferred from electronic annotation 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030667 // secretory granule membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation /// 0070044 // synaptobrevin 2-SNAP-25-syntaxin-1a complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement 0000149 // SNARE binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // not recorded /// 0032403 // protein complex binding // inferred from electronic annotation 201558_at NM_003610 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003610.1 /DEF=Homo sapiens RAE1 (RNA export 1, S.pombe) homolog (RAE1), mRNA. /FEA=mRNA /GEN=RAE1 /PROD=RAE1 (RNA export 1, S.pombe) homolog /DB_XREF=gi:4506398 /UG=Hs.196209 RAE1 (RNA export 1, S.pombe) homolog /FL=gb:U84720.1 gb:NM_003610.1" NM_003610 ribonucleic acid export 1 RAE1 8480 NM_001015885 /// NM_003610 /// XM_005260582 /// XM_005260583 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005640 // nuclear outer membrane // traceable author statement /// 0005643 // nuclear pore // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity 201559_s_at AF109196 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF109196.1 /DEF=Homo sapiens intracellular chloride channel p64H1 mRNA, complete cds. /FEA=mRNA /PROD=intracellular chloride channel p64H1 /DB_XREF=gi:4588523 /UG=Hs.25035 chloride intracellular channel 4 /FL=gb:AF109196.1 gb:AF097330.1 gb:AL117424.1 gb:NM_013943.1" AF109196 chloride intracellular channel 4 CLIC4 25932 NM_013943 0001525 // angiogenesis // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // non-traceable author statement /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201560_at NM_013943 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013943.1 /DEF=Homo sapiens chloride intracellular channel 4 (CLIC4), mRNA. /FEA=mRNA /GEN=CLIC4 /PROD=chloride intracellular channel 4 /DB_XREF=gi:7330334 /UG=Hs.25035 chloride intracellular channel 4 /FL=gb:AF109196.1 gb:AF097330.1 gb:AL117424.1 gb:NM_013943.1" NM_013943 chloride intracellular channel 4 CLIC4 25932 NM_013943 0001525 // angiogenesis // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0007035 // vacuolar acidification // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0035088 // establishment or maintenance of apical/basal cell polarity // non-traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // non-traceable author statement /// 0061299 // retina vasculature morphogenesis in camera-type eye // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from mutant phenotype /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201561_s_at NM_014944 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014944.1 /DEF=Homo sapiens KIAA0911 protein (KIAA0911), mRNA. /FEA=mRNA /GEN=KIAA0911 /PROD=KIAA0911 protein /DB_XREF=gi:7662373 /UG=Hs.29665 KIAA0911 protein /FL=gb:AB020718.1 gb:NM_014944.1" NM_014944 calsyntenin 1 CLSTN1 22883 NM_001009566 /// NM_014944 /// XM_005263432 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction /// 0042988 // X11-like protein binding // inferred from physical interaction 201562_s_at NM_003104 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003104.1 /DEF=Homo sapiens sorbitol dehydrogenase (SORD), mRNA. /FEA=mRNA /GEN=SORD /PROD=sorbitol dehydrogenase /DB_XREF=gi:4507154 /UG=Hs.878 sorbitol dehydrogenase /FL=gb:NM_003104.1 gb:L29008.1 gb:U07361.1" NM_003104 sorbitol dehydrogenase SORD 6652 NM_003104 /// NR_034039 0006006 // glucose metabolic process // traceable author statement /// 0006060 // sorbitol metabolic process // inferred from electronic annotation /// 0006062 // sorbitol catabolic process // inferred from direct assay /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0030317 // sperm motility // non-traceable author statement /// 0046370 // fructose biosynthetic process // inferred from direct assay /// 0051160 // L-xylitol catabolic process // inferred from direct assay /// 0051164 // L-xylitol metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003939 // L-iditol 2-dehydrogenase activity // inferred from direct assay /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay" 201563_at L29008 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L29008.1 /DEF=Human L-iditol-2 dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=L-iditol-2 dehydrogenase /DB_XREF=gi:496077 /UG=Hs.878 sorbitol dehydrogenase /FL=gb:NM_003104.1 gb:L29008.1 gb:U07361.1" L29008 sorbitol dehydrogenase SORD 6652 NM_003104 /// NR_034039 0006006 // glucose metabolic process // traceable author statement /// 0006060 // sorbitol metabolic process // inferred from electronic annotation /// 0006062 // sorbitol catabolic process // inferred from direct assay /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0030317 // sperm motility // non-traceable author statement /// 0046370 // fructose biosynthetic process // inferred from direct assay /// 0051160 // L-xylitol catabolic process // inferred from direct assay /// 0051164 // L-xylitol metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003939 // L-iditol 2-dehydrogenase activity // inferred from direct assay /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay" 201564_s_at NM_003088 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003088.1 /DEF=Homo sapiens singed (Drosophila)-like (sea urchin fascin homolog like) (SNL), mRNA. /FEA=mRNA /GEN=SNL /PROD=singed (Drosophila)-like (sea urchin fascinhomolog like) /DB_XREF=gi:4507114 /UG=Hs.118400 singed (Drosophila)-like (sea urchin fascin homolog like) /FL=gb:BC000521.1 gb:NM_003088.1 gb:U03057.1 gb:U09873.1" NM_003088 fascin actin-bundling protein 1 FSCN1 6624 NM_003088 0008283 // cell proliferation // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0048870 // cell motility // inferred from direct assay /// 0051017 // actin filament bundle assembly // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071437 // invadopodium // inferred from direct assay "0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay" 201565_s_at NM_002166 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002166.1 /DEF=Homo sapiens inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2), mRNA. /FEA=mRNA /GEN=ID2 /PROD=inhibitor of DNA binding 2, dominant negativehelix-loop-helix protein /DB_XREF=gi:4504570 /UG=Hs.180919 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /FL=gb:M97796.1 gb:NM_002166.1 gb:D13891.1" NM_002166 "inhibitor of DNA binding 2, dominant negative helix-loop-helix protein" ID2 3398 NM_002166 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033598 // mammary gland epithelial cell proliferation // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045578 // negative regulation of B cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred by curator /// 0090398 // cellular senescence // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from sequence or structural similarity" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 201566_x_at D13891 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D13891.1 /DEF=Human mRNA for Id-2H, complete cds. /FEA=mRNA /GEN=Id-2H /PROD=Id-2H /DB_XREF=gi:464183 /UG=Hs.180919 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /FL=gb:M97796.1 gb:NM_002166.1 gb:D13891.1" D13891 "inhibitor of DNA binding 2, dominant negative helix-loop-helix protein" ID2 3398 NM_002166 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003166 // bundle of His development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033598 // mammary gland epithelial cell proliferation // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045578 // negative regulation of B cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061030 // epithelial cell differentiation involved in mammary gland alveolus development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071931 // positive regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred by curator /// 0090398 // cellular senescence // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 2000178 // negative regulation of neural precursor cell proliferation // inferred from sequence or structural similarity" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 201567_s_at NM_002078 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002078.2 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA. /FEA=mRNA /GEN=GOLGA4 /PROD=golgi autoantigen, golgin subfamily a, 4 /DB_XREF=gi:6715599 /UG=Hs.183773 golgi autoantigen, golgin subfamily a, 4 /FL=gb:U41740.1 gb:NM_002078.2" NM_002078 golgin A4 GOLGA4 2803 NM_001172713 /// NM_002078 /// XM_005265069 /// XM_005265070 /// XM_005265071 /// XM_005265072 /// XM_005265073 /// XM_005265074 /// XM_005265075 /// XM_006713110 0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from physical interaction 201568_at NM_014402 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014402.1 /DEF=Homo sapiens low molecular mass ubiquinone-binding protein (9.5kD) (QP-C), mRNA. /FEA=mRNA /GEN=QP-C /PROD=low molecular mass ubiquinone-binding protein /DB_XREF=gi:7657485 /UG=Hs.3709 low molecular mass ubiquinone-binding protein (9.5kD) /FL=gb:BC001390.1 gb:D50369.1 gb:NM_014402.1" NM_014402 "ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa" UQCRQ 27089 NM_014402 0021539 // subthalamus development // inferred from electronic annotation /// 0021548 // pons development // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021794 // thalamus development // inferred from electronic annotation /// 0021854 // hypothalamus development // inferred from electronic annotation /// 0021860 // pyramidal neuron development // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation 201569_s_at NM_015380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015380.1 /DEF=Homo sapiens CGI-51 protein (CGI-51), mRNA. /FEA=mRNA /GEN=CGI-51 /PROD=CGI-51 protein /DB_XREF=gi:7661541 /UG=Hs.4877 CGI-51 protein /FL=gb:AF151809.1 gb:NM_015380.1" NM_015380 SAMM50 sorting and assembly machinery component SAMM50 25813 NM_015380 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay 0001401 // mitochondrial sorting and assembly machinery complex // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0019867 // outer membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201570_at NM_015380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015380.1 /DEF=Homo sapiens CGI-51 protein (CGI-51), mRNA. /FEA=mRNA /GEN=CGI-51 /PROD=CGI-51 protein /DB_XREF=gi:7661541 /UG=Hs.4877 CGI-51 protein /FL=gb:AF151809.1 gb:NM_015380.1" NM_015380 SAMM50 sorting and assembly machinery component SAMM50 25813 NM_015380 0006626 // protein targeting to mitochondrion // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045040 // protein import into mitochondrial outer membrane // inferred from direct assay 0001401 // mitochondrial sorting and assembly machinery complex // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0019867 // outer membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201571_s_at AI656493 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI656493 /FEA=EST /DB_XREF=gi:4740472 /DB_XREF=est:tt51d09.x1 /CLONE=IMAGE:2244305 /UG=Hs.76894 dCMP deaminase /FL=gb:L12136.1 gb:NM_001921.1 AI656493 dCMP deaminase DCTD 1635 NM_001012732 /// NM_001921 /// XM_005262778 /// XM_005262779 /// XM_005262780 /// XM_005262781 /// XM_005262782 /// XM_006714113 /// XM_006714114 /// XM_006714115 /// XM_006714116 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004132 // dCMP deaminase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201572_x_at NM_001921 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001921.1 /DEF=Homo sapiens dCMP deaminase (DCTD), mRNA. /FEA=mRNA /GEN=DCTD /PROD=dCMP deaminase /DB_XREF=gi:4503276 /UG=Hs.76894 dCMP deaminase /FL=gb:L12136.1 gb:NM_001921.1" NM_001921 dCMP deaminase DCTD 1635 NM_001012732 /// NM_001921 /// XM_005262778 /// XM_005262779 /// XM_005262780 /// XM_005262781 /// XM_005262782 /// XM_006714113 /// XM_006714114 /// XM_006714115 /// XM_006714116 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004132 // dCMP deaminase activity // not recorded /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201573_s_at M75715 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M75715.1 /DEF=Human TB3-1 mRNA, complete cds. /FEA=mRNA /PROD=TB3-1 /DB_XREF=gi:338686 /UG=Hs.77324 eukaryotic translation termination factor 1 /FL=gb:U90176.1 gb:M75715.1 gb:NM_004730.1" M75715 eukaryotic translation termination factor 1 ETF1 2107 NM_001256302 /// NM_001282185 /// NM_001291974 /// NM_001291975 /// NM_004730 /// XM_005271920 /// XM_005271921 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006449 // regulation of translational termination // traceable author statement /// 0006479 // protein methylation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement "0003723 // RNA binding // traceable author statement /// 0003747 // translation release factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008079 // translation termination factor activity // traceable author statement /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation /// 0043022 // ribosome binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201574_at NM_004730 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004730.1 /DEF=Homo sapiens eukaryotic translation termination factor 1 (ETF1), mRNA. /FEA=mRNA /GEN=ETF1 /PROD=eukaryotic translation termination factor 1 /DB_XREF=gi:4759033 /UG=Hs.77324 eukaryotic translation termination factor 1 /FL=gb:U90176.1 gb:M75715.1 gb:NM_004730.1" NM_004730 eukaryotic translation termination factor 1 ETF1 2107 NM_001256302 /// NM_001282185 /// NM_001291974 /// NM_001291975 /// NM_004730 /// XM_005271920 /// XM_005271921 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006449 // regulation of translational termination // traceable author statement /// 0006479 // protein methylation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement "0003723 // RNA binding // traceable author statement /// 0003747 // translation release factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008079 // translation termination factor activity // traceable author statement /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation /// 0043022 // ribosome binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201575_at NM_012245 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012245.1 /DEF=Homo sapiens SKI-INTERACTING PROTEIN (SNW1), mRNA. /FEA=mRNA /GEN=SNW1 /PROD=SKI-INTERACTING PROTEIN /DB_XREF=gi:6912675 /UG=Hs.79008 SKI-INTERACTING PROTEIN /FL=gb:U51432.1 gb:AF045184.1 gb:NM_012245.1" NM_012245 SNW domain containing 1 SNW1 22938 NM_012245 /// XM_005267413 /// XM_005267414 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048385 // regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0070564 // positive regulation of vitamin D receptor signaling pathway // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from direct assay" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay /// 0071146 // SMAD3-SMAD4 protein complex // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from direct assay /// 0042974 // retinoic acid receptor binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay 201576_s_at NM_000404 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000404.1 /DEF=Homo sapiens galactosidase, beta 1 (GLB1), mRNA. /FEA=mRNA /GEN=GLB1 /PROD=galactosidase, beta 1 /DB_XREF=gi:10834965 /UG=Hs.79222 galactosidase, beta 1 /FL=gb:NM_000404.1 gb:M27507.1 gb:M22590.1 gb:M34423.1" NM_000404 "galactosidase, beta 1 /// transmembrane protein with metallophosphoesterase domain" GLB1 /// TMPPE 2720 /// 643853 NM_000404 /// NM_001039770 /// NM_001079811 /// NM_001135602 /// NM_001136238 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019388 // galactose catabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0009341 // beta-galactosidase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004565 // beta-galactosidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016936 // galactoside binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201577_at NM_000269 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000269.1 /DEF=Homo sapiens non-metastatic cells 1, protein (NM23A) expressed in (NME1), mRNA. /FEA=mRNA /GEN=NME1 /PROD=non-metastatic cells 1 protein /DB_XREF=gi:4557796 /UG=Hs.118638 non-metastatic cells 1, protein (NM23A) expressed in /FL=gb:BC000293.1 gb:NM_000269.1" NM_000269 NME/NM23 nucleoside diphosphate kinase 1 NME1 4830 NM_000269 /// NM_198175 "0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from electronic annotation /// 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006308 // DNA catabolic process // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018106 // peptidyl-histidine phosphorylation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045682 // regulation of epidermis development // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation" 0001726 // ruffle // inferred from direct assay /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004536 // deoxyribonuclease activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0004673 // protein histidine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation /// 0043024 // ribosomal small subunit binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201578_at NM_005397 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005397.1 /DEF=Homo sapiens podocalyxin-like (PODXL), mRNA. /FEA=mRNA /GEN=PODXL /PROD=podocalyxin-like /DB_XREF=gi:4885556 /UG=Hs.16426 podocalyxin-like /FL=gb:U97519.1 gb:NM_005397.1" NM_005397 podocalyxin-like PODXL 5420 NM_001018111 /// NM_005397 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0022408 // negative regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032534 // regulation of microvillus assembly // inferred from sequence or structural similarity /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity /// 0072175 // epithelial tube formation // inferred from sequence or structural similarity 0001726 // ruffle // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031528 // microvillus membrane // inferred from sequence or structural similarity /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201579_at NM_005245 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005245.1 /DEF=Homo sapiens FAT tumor suppressor (Drosophila) homolog (FAT), mRNA. /FEA=mRNA /GEN=FAT /PROD=FAT tumor suppressor precursor /DB_XREF=gi:4885228 /UG=Hs.166994 FAT tumor suppressor (Drosophila) homolog /FL=gb:NM_005245.1" NM_005245 FAT atypical cadherin 1 FAT1 2195 NM_005245 /// XM_005262834 /// XM_005262835 /// XM_006714139 0007015 // actin filament organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201580_s_at AL544094 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL544094 /FEA=EST /DB_XREF=gi:12876573 /DB_XREF=est:AL544094 /CLONE=CS0DI004YG20 (3 prime) /UG=Hs.169358 hypothetical protein /FL=gb:NM_021156.1 AL544094 thioredoxin-related transmembrane protein 4 TMX4 56255 NM_021156 0006457 // protein folding // not recorded /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded 201581_at BF572868 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF572868 /FEA=EST /DB_XREF=gi:11646580 /DB_XREF=est:602079440F2 /CLONE=IMAGE:4254176 /UG=Hs.169358 hypothetical protein /FL=gb:NM_021156.1 BF572868 thioredoxin-related transmembrane protein 4 TMX4 56255 NM_021156 0006457 // protein folding // not recorded /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // not recorded 201582_at AL121900 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL121900 /DEF=Human DNA sequence from clone RP11-379J5 on chromosome 20 Contains the last exon of the SEC23B gene for Sec23 (S. cerevisiae) homolog B, a putative novel gene, the 5 end of the gene for a novel protein similar to bacterial histidyl-tRNA synthetas... /FEA=mRNA /DB_XREF=gi:11121203 /UG=Hs.173497 Sec23 (S. cerevisiae) homolog B /FL=gb:BC005404.1 gb:NM_006363.1" AL121900 Sec23 homolog B (S. cerevisiae) SEC23B 10483 NM_001172745 /// NM_001172746 /// NM_006363 /// NM_032985 /// NM_032986 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 201583_s_at NM_006363 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006363.1 /DEF=Homo sapiens Sec23 (S. cerevisiae) homolog B (SEC23B), mRNA. /FEA=mRNA /GEN=SEC23B /PROD=Sec23 (S. cerevisiae) homolog B /DB_XREF=gi:5454043 /UG=Hs.173497 Sec23 (S. cerevisiae) homolog B /FL=gb:BC005404.1 gb:NM_006363.1" NM_006363 Sec23 homolog B (S. cerevisiae) SEC23B 10483 NM_001172745 /// NM_001172746 /// NM_006363 /// NM_032985 /// NM_032986 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 201584_s_at NM_005804 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005804.1 /DEF=Homo sapiens nuclear RNA helicase, DECD variant of DEAD box family (DDXL), mRNA. /FEA=mRNA /GEN=DDXL /PROD=nuclear RNA helicase, DECD variant of DEAD boxfamily /DB_XREF=gi:5031658 /UG=Hs.179606 nuclear RNA helicase, DECD variant of DEAD box family /FL=gb:BC001009.1 gb:U90426.1 gb:NM_005804.1" NM_005804 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A DDX39A 10212 NM_001204057 /// NM_005804 /// NM_138998 /// NR_038336 /// NR_046366 /// XM_006722606 "0000398 // mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201585_s_at BG035151 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG035151 /FEA=EST /DB_XREF=gi:12428997 /DB_XREF=est:602324851F1 /CLONE=IMAGE:4412917 /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) /FL=gb:NM_005066.1 BG035151 splicing factor proline/glutamine-rich SFPQ 6421 NM_005066 /// XM_005271111 /// XM_005271112 /// XM_005271113 /// XM_005271115 /// XM_005271116 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201586_s_at NM_005066 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005066.1 /DEF=Homo sapiens splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) (SFPQ), mRNA. /FEA=mRNA /GEN=SFPQ /PROD=splicing factor prolineglutamine rich(polypyrimidine tract-binding protein-associated) /DB_XREF=gi:4826997 /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) /FL=gb:NM_005066.1" NM_005066 splicing factor proline/glutamine-rich SFPQ 6421 NM_005066 /// XM_005271111 /// XM_005271112 /// XM_005271113 /// XM_005271115 /// XM_005271116 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000380 // alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201587_s_at NM_001569 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001569.2 /DEF=Homo sapiens interleukin-1 receptor-associated kinase 1 (IRAK1), mRNA. /FEA=mRNA /GEN=IRAK1 /PROD=interleukin-1 receptor-associated kinase 1 /DB_XREF=gi:4755143 /UG=Hs.182018 interleukin-1 receptor-associated kinase 1 /FL=gb:L76191.1 gb:NM_001569.2" NM_001569 interleukin-1 receptor-associated kinase 1 IRAK1 3654 NM_001025242 /// NM_001025243 /// NM_001569 /// XM_005274668 "0000187 // activation of MAPK activity // traceable author statement /// 0001959 // regulation of cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // non-traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051259 // protein oligomerization // inferred from mutant phenotype /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0045323 // interleukin-1 receptor complex // non-traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004704 // NF-kappaB-inducing kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction" 201588_at NM_004786 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004786.1 /DEF=Homo sapiens thioredoxin-like, 32kD (TXNL), mRNA. /FEA=mRNA /GEN=TXNL /PROD=thioredoxin-like, 32kD /DB_XREF=gi:4759273 /UG=Hs.18792 thioredoxin-like, 32kD /FL=gb:BC001156.1 gb:AF003938.1 gb:AF051896.1 gb:AF052659.1 gb:NM_004786.1" NM_004786 thioredoxin-like 1 TXNL1 9352 NM_004786 /// NR_024546 /// XM_006722580 /// XM_006722581 /// XR_430086 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015036 // disulfide oxidoreductase activity // inferred from direct assay 201589_at D80000 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:D80000.1 /DEF=Human mRNA for KIAA0178 gene, partial cds. /FEA=mRNA /GEN=KIAA0178 /DB_XREF=gi:1136415 /UG=Hs.211602 SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 /FL=gb:NM_006306.1" D80000 structural maintenance of chromosomes 1A SMC1A 8243 NM_001281463 /// NM_006306 "0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007062 // sister chromatid cohesion // inferred from mutant phenotype /// 0007064 // mitotic sister chromatid cohesion // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from sequence or structural similarity /// 0008380 // RNA splicing // traceable author statement /// 0009314 // response to radiation // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0032876 // negative regulation of DNA endoreduplication // inferred from mutant phenotype /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" "0000775 // chromosome, centromeric region // traceable author statement /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008278 // cohesin complex // inferred from electronic annotation /// 0008280 // cohesin core heterodimer // traceable author statement /// 0030893 // meiotic cohesin complex // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0036033 // mediator complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201590_x_at NM_004039 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004039.1 /DEF=Homo sapiens annexin A2 (ANXA2), mRNA. /FEA=mRNA /GEN=ANXA2 /PROD=annexin A2 /DB_XREF=gi:4757755 /UG=Hs.217493 annexin A2 /FL=gb:BC001748.1 gb:D00017.1 gb:NM_004039.1" NM_004039 annexin A2 ANXA2 302 NM_001002857 /// NM_001002858 /// NM_001136015 /// NM_004039 0001525 // angiogenesis // inferred from expression pattern /// 0001765 // membrane raft assembly // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006900 // membrane budding // inferred from mutant phenotype /// 0007589 // body fluid secretion // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from direct assay /// 0036035 // osteoclast development // inferred from direct assay /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051099 // positive regulation of binding // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from direct assay /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031902 // late endosome membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044354 // macropinosome // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from mutant phenotype /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048306 // calcium-dependent protein binding // inferred from physical interaction" 201591_s_at NM_007184 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007184.1 /DEF=Homo sapiens imidazoline receptor candidate (I-1), mRNA. /FEA=mRNA /GEN=I-1 /PROD=imidazoline receptor candidate /DB_XREF=gi:6005787 /UG=Hs.26285 imidazoline receptor candidate /FL=gb:AF082516.1 gb:NM_007184.1" NM_007184 nischarin NISCH 11188 NM_001276293 /// NM_001276294 /// NM_007184 /// XM_005264839 /// XM_006712955 "0006006 // glucose metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0048243 // norepinephrine secretion // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008227 // G-protein coupled amine receptor activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201592_at NM_003756 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003756.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) (EIF3S3), mRNA. /FEA=mRNA /GEN=EIF3S3 /PROD=eukaryotic translation initiation factor 3,subunit 3 (gamma, 40kD) /DB_XREF=gi:4503514 /UG=Hs.58189 eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) /FL=gb:BC000386.1 gb:U54559.1 gb:NM_003756.1" NM_003756 "eukaryotic translation initiation factor 3, subunit H" EIF3H 8667 NM_003756 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201593_s_at AV716798 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV716798 /FEA=EST /DB_XREF=gi:10813950 /DB_XREF=est:AV716798 /CLONE=DCBAKB02 /UG=Hs.6375 uncharacterized hypothalamus protein HT010 /FL=gb:AF220184.1 gb:NM_018471.1 AV716798 zinc finger CCCH-type containing 15 ZC3H15 55854 NM_018471 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201594_s_at NM_005134 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005134.1 /DEF=Homo sapiens protein phosphatase 4, regulatory subunit 1 (PPP4R1), mRNA. /FEA=mRNA /GEN=PPP4R1 /PROD=protein phosphatase 4, regulatory subunit 1 /DB_XREF=gi:4826933 /UG=Hs.3382 protein phosphatase 4, regulatory subunit 1 /FL=gb:AF111106.1 gb:NM_005134.1 gb:AF100744.1" NM_005134 "protein phosphatase 4, regulatory subunit 1" PPP4R1 9989 NM_001042388 /// NM_005134 /// NR_052003 /// XR_430048 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // non-traceable author statement 0030289 // protein phosphatase 4 complex // inferred from sequence or structural similarity 0004721 // phosphoprotein phosphatase activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030362 // protein phosphatase type 4 regulator activity // non-traceable author statement 201595_s_at NM_018471 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018471.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HT010 (HT010), mRNA. /FEA=mRNA /GEN=HT010 /PROD=uncharacterized hypothalamus protein HT010 /DB_XREF=gi:8923807 /UG=Hs.6375 uncharacterized hypothalamus protein HT010 /FL=gb:AF220184.1 gb:NM_018471.1" NM_018471 zinc finger CCCH-type containing 15 ZC3H15 55854 NM_018471 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201596_x_at NM_000224 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000224.1 /DEF=Homo sapiens keratin 18 (KRT18), mRNA. /FEA=mRNA /GEN=KRT18 /PROD=keratin 18 /DB_XREF=gi:4557887 /UG=Hs.65114 keratin 18 /FL=gb:BC000698.1 gb:BC000180.2 gb:BC004253.1 gb:M26326.1 gb:NM_000224.1" NM_000224 keratin 18 KRT18 3875 NM_000224 /// NM_199187 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0043000 // Golgi to plasma membrane CFTR protein transport // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045104 // intermediate filament cytoskeleton organization // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005882 // intermediate filament // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction 201597_at NM_001865 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001865.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (COX7A2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX7A2 /PROD=cytochrome c oxidase subunit VIIa polypeptide 2(liver) /DB_XREF=gi:4502988 /UG=Hs.70312 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) /FL=gb:NM_001865.1" NM_001865 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) COX7A2 1347 NM_001865 /// NR_029466 /// XM_006715335 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 201598_s_at NM_001567 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001567.2 /DEF=Homo sapiens inositol polyphosphate phosphatase-like 1 (INPPL1), mRNA. /FEA=mRNA /GEN=INPPL1 /PROD=inositol polyphosphate phosphatase-like 1 /DB_XREF=gi:4755141 /UG=Hs.75339 inositol polyphosphate phosphatase-like 1 /FL=gb:NM_001567.2 gb:L24444.1" NM_001567 inositol polyphosphate phosphatase-like 1 INPPL1 3636 NM_001567 /// XM_005273978 /// XM_005273979 /// XM_006718534 /// XM_006718535 /// XM_006718536 /// XM_006718537 0001958 // endochondral ossification // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006897 // endocytosis // inferred from mutant phenotype /// 0007015 // actin filament organization // inferred from mutant phenotype /// 0007155 // cell adhesion // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032957 // inositol trisphosphate metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0097178 // ruffle assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation "0003779 // actin binding // inferred from electronic annotation /// 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction" 201599_at NM_000274 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000274.1 /DEF=Homo sapiens ornithine aminotransferase (gyrate atrophy) (OAT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=OAT /PROD=ornithine aminotransferase precursor /DB_XREF=gi:4557808 /UG=Hs.75485 ornithine aminotransferase (gyrate atrophy) /FL=gb:BC000964.1 gb:M12267.1 gb:M23204.1 gb:M14963.1 gb:NM_000274.1" NM_000274 ornithine aminotransferase OAT 4942 NM_000274 /// NM_001171814 /// XM_006717871 0007601 // visual perception // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0034214 // protein hexamerization // inferred from direct assay /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055129 // L-proline biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004587 // ornithine-oxo-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 201600_at NM_007273 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007273.1 /DEF=Homo sapiens B-cell associated protein (REA), mRNA. /FEA=mRNA /GEN=REA /PROD=B-cell associated protein /DB_XREF=gi:6005853 /UG=Hs.7771 B-cell associated protein /FL=gb:AF150962.1 gb:NM_007273.1 gb:AF126021.1 gb:AF178980.1" NM_007273 prohibitin 2 PHB2 11331 NM_001144831 /// NM_001267700 /// XR_242980 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0033147 // negative regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033600 // negative regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // non-traceable author statement 201601_x_at NM_003641 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003641.1 /DEF=Homo sapiens interferon induced transmembrane protein 1 (9-27) (IFITM1), mRNA. /FEA=mRNA /GEN=IFITM1 /PROD=interferon induced transmembrane protein 1(9-27) /DB_XREF=gi:4504580 /UG=Hs.146360 interferon induced transmembrane protein 1 (9-27) /FL=gb:BC000897.1 gb:J04164.1 gb:NM_003641.1" NM_003641 interferon induced transmembrane protein 1 /// interferon induced transmembrane protein 2 IFITM1 /// IFITM2 8519 /// 10581 NM_003641 /// NM_006435 0001503 // ossification // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009607 // response to biotic stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0035456 // response to interferon-beta // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201602_s_at BE737620 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE737620 /FEA=EST /DB_XREF=gi:10151612 /DB_XREF=est:601572895F1 /CLONE=IMAGE:3839831 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1" BE737620 "protein phosphatase 1, regulatory subunit 12A" PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_001244990 /// NM_001244992 /// NM_002480 /// XM_005268885 /// XM_005268886 /// XM_005268887 /// XM_005268888 /// XM_005268889 /// XM_005268891 /// XM_005268892 /// XM_005268893 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0035507 // regulation of myosin-light-chain-phosphatase activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype 0000776 // kinetochore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043292 // contractile fiber // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019208 // phosphatase regulator activity // inferred from direct assay /// 0019208 // phosphatase regulator activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201603_at AI817061 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI817061 /FEA=EST /DB_XREF=gi:5436140 /DB_XREF=est:wj76e05.x1 /CLONE=IMAGE:2408768 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1" AI817061 "protein phosphatase 1, regulatory subunit 12A" PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_001244990 /// NM_001244992 /// NM_002480 /// XM_005268885 /// XM_005268886 /// XM_005268887 /// XM_005268888 /// XM_005268889 /// XM_005268891 /// XM_005268892 /// XM_005268893 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0035507 // regulation of myosin-light-chain-phosphatase activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype 0000776 // kinetochore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043292 // contractile fiber // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019208 // phosphatase regulator activity // inferred from direct assay /// 0019208 // phosphatase regulator activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201604_s_at NM_002480 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002480.1 /DEF=Homo sapiens myosin phosphatase, target subunit 1 (MYPT1), mRNA. /FEA=mRNA /GEN=MYPT1 /PROD=myosin phosphatase target subunit 1 /DB_XREF=gi:4505316 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1" NM_002480 "protein phosphatase 1, regulatory subunit 12A" PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_001244990 /// NM_001244992 /// NM_002480 /// XM_005268885 /// XM_005268886 /// XM_005268887 /// XM_005268888 /// XM_005268889 /// XM_005268891 /// XM_005268892 /// XM_005268893 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0035507 // regulation of myosin-light-chain-phosphatase activity // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype 0000776 // kinetochore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0043292 // contractile fiber // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019208 // phosphatase regulator activity // inferred from direct assay /// 0019208 // phosphatase regulator activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 201605_x_at NM_004368 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004368.1 /DEF=Homo sapiens calponin 2 (CNN2), mRNA. /FEA=mRNA /GEN=CNN2 /PROD=calponin 2 /DB_XREF=gi:4758017 /UG=Hs.169718 calponin 2 /FL=gb:D83735.1 gb:NM_004368.1" NM_004368 calponin 2 CNN2 1265 NM_004368 /// NM_201277 0007010 // cytoskeleton organization // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031032 // actomyosin structure organization // inferred from electronic annotation /// 0032970 // regulation of actin filament-based process // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 201606_s_at BE796924 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE796924 /FEA=EST /DB_XREF=gi:10218031 /DB_XREF=est:601587284F1 /CLONE=IMAGE:3941445 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 BE796924 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 "0006351 // transcription, DNA-templated // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201607_at AI694451 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI694451 /FEA=EST /DB_XREF=gi:4971791 /DB_XREF=est:wd83h06.x1 /CLONE=IMAGE:2338235 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 AI694451 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 "0006351 // transcription, DNA-templated // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201608_s_at NM_007062 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007062.1 /DEF=Homo sapiens nuclear phosphoprotein similar to S. cerevisiae PWP1 (PWP1), mRNA. /FEA=mRNA /GEN=PWP1 /PROD=nuclear phosphoprotein similar to S. cerevisiaePWP1 /DB_XREF=gi:5902033 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1" NM_007062 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 "0006351 // transcription, DNA-templated // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201609_x_at AL578502 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL578502 /FEA=EST /DB_XREF=gi:12942638 /DB_XREF=est:AL578502 /CLONE=CS0DK011YK08 (3 prime) /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1 AL578502 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 /// NM_170705 /// XM_005263437 /// XM_006710518 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006479 // protein methylation // inferred from electronic annotation /// 0006481 // C-terminal protein methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003880 // protein C-terminal carboxyl O-methyltransferase activity // traceable author statement /// 0004671 // protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201610_at AF064084 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF064084.1 /DEF=Homo sapiens prenylcysteine carboxyl methyltransferase (PCCMT) mRNA, complete cds. /FEA=mRNA /GEN=PCCMT /PROD=prenylcysteine carboxyl methyltransferase /DB_XREF=gi:3135668 /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1" AF064084 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 /// NM_170705 /// XM_005263437 /// XM_006710518 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006479 // protein methylation // inferred from electronic annotation /// 0006481 // C-terminal protein methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003880 // protein C-terminal carboxyl O-methyltransferase activity // traceable author statement /// 0004671 // protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201611_s_at NM_012405 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012405.1 /DEF=Homo sapiens isoprenylcysteine carboxyl methyltransferase (ICMT), mRNA. /FEA=mRNA /GEN=ICMT /PROD=isoprenylcysteine carboxyl methyltransferase /DB_XREF=gi:6912429 /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1" NM_012405 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 /// NM_170705 /// XM_005263437 /// XM_006710518 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006479 // protein methylation // inferred from electronic annotation /// 0006481 // C-terminal protein methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003880 // protein C-terminal carboxyl O-methyltransferase activity // traceable author statement /// 0004671 // protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201612_at NM_000696 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000696.1 /DEF=Homo sapiens aldehyde dehydrogenase 9 (gamma-aminobutyraldehyde dehydrogenase, E3 isozyme) (ALDH9), mRNA. /FEA=mRNA /GEN=ALDH9 /PROD=aldehyde dehydrogenase 9(gamma-aminobutyraldehyde dehydrogenase, E3 isozyme) /DB_XREF=gi:4502046 /UG=Hs.2533 aldehyde dehydrogenase 9 family, member A1 /FL=gb:U34252.1 gb:NM_000696.1 gb:AF172093.1" NM_000696 "aldehyde dehydrogenase 9 family, member A1" ALDH9A1 223 NM_000696 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042136 // neurotransmitter biosynthetic process // inferred from direct assay /// 0042445 // hormone metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // inferred from electronic annotation /// 0045329 // carnitine biosynthetic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004028 // 3-chloroallyl aldehyde dehydrogenase activity // traceable author statement /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019145 // aminobutyraldehyde dehydrogenase activity // inferred from direct assay /// 0033737 // 1-pyrroline dehydrogenase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043176 // amine binding // inferred from electronic annotation /// 0047105 // 4-trimethylammoniobutyraldehyde dehydrogenase activity // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 201613_s_at BC000519 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000519.1 /DEF=Homo sapiens, RuvB (E coli homolog)-like 1, clone MGC:8557, mRNA, complete cds. /FEA=mRNA /PROD=RuvB (E coli homolog)-like 1 /DB_XREF=gi:12653494 /UG=Hs.272822 RuvB (E coli homolog)-like 1 /FL=gb:BC000519.1 gb:BC002993.1 gb:AB012122.1 gb:AF070735.1 gb:AF099084.1 gb:NM_003707.1" BC000519 "adaptor-related protein complex 1, gamma 2 subunit" AP1G2 8906 NM_001282474 /// NM_001282475 /// NM_003917 /// NM_080545 /// XM_005268166 /// XM_005268167 /// XM_005268168 /// XM_005268169 /// XM_005268170 /// XM_005268171 /// XM_005268172 /// XM_005268173 /// XM_005268174 /// XM_005268175 /// XM_005268176 /// XM_005268177 /// XM_005268178 /// XM_005268179 /// XM_005268180 /// XM_005268181 /// XM_005268182 /// XM_006720301 /// XR_245729 /// XR_245730 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 201614_s_at NM_003707 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003707.1 /DEF=Homo sapiens RuvB (E coli homolog)-like 1 (RUVBL1), mRNA. /FEA=mRNA /GEN=RUVBL1 /PROD=TATA binding protein interacting protein 49 kDa /DB_XREF=gi:4506752 /UG=Hs.272822 RuvB (E coli homolog)-like 1 /FL=gb:BC000519.1 gb:BC002993.1 gb:AB012122.1 gb:AF070735.1 gb:AF099084.1 gb:NM_003707.1" NM_003707 RuvB-like AAA ATPase 1 RUVBL1 8607 NM_003707 /// XM_005247841 "0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation" 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0043141 // ATP-dependent 5'-3' DNA helicase activity // inferred from electronic annotation 201615_x_at AI685060 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI685060 /FEA=EST /DB_XREF=gi:4896365 /DB_XREF=est:wc67a07.x1 /CLONE=IMAGE:2323668 /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 AI685060 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201616_s_at AL577531 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL577531 /FEA=EST /DB_XREF=gi:12940753 /DB_XREF=est:AL577531 /CLONE=CS0DI087YP20 (3 prime) /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 AL577531 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201617_x_at NM_004342 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004342.2 /DEF=Homo sapiens caldesmon 1 (CALD1), mRNA. /FEA=mRNA /GEN=CALD1 /PROD=caldesmon 1 /DB_XREF=gi:11091984 /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1" NM_004342 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 /// XM_006716136 /// XM_006716137 /// XM_006716138 /// XM_006716139 0006928 // cellular component movement // traceable author statement /// 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030478 // actin cap // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201618_x_at NM_003801 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003801.2 /DEF=Homo sapiens anchor attachment protein 1 (Gaa1p, yeast) homolog (GPAA1), mRNA. /FEA=mRNA /GEN=GPAA1 /PROD=anchor attachment protein 1 /DB_XREF=gi:6031166 /UG=Hs.4742 anchor attachment protein 1 (Gaa1p, yeast) homolog /FL=gb:BC003171.1 gb:BC004129.1 gb:AB006969.1 gb:AB002135.1 gb:NM_003801.2" NM_003801 glycosylphosphatidylinositol anchor attachment 1 GPAA1 8733 NM_003801 0006461 // protein complex assembly // non-traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042765 // GPI-anchor transamidase complex // traceable author statement 0003923 // GPI-anchor transamidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // non-traceable author statement /// 0034235 // GPI anchor binding // inferred from mutant phenotype 201619_at NM_006793 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006793.1 /DEF=Homo sapiens peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PRDX3 /PROD=peroxiredoxin 3 /DB_XREF=gi:5802973 /UG=Hs.75454 peroxiredoxin 3 /FL=gb:BC002685.1 gb:NM_006793.1 gb:D49396.1" NM_006793 peroxiredoxin 3 PRDX3 10935 NM_006793 /// NM_014098 0001893 // maternal placenta development // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0018171 // peptidyl-cysteine oxidation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from genetic interaction /// 0042744 // hydrogen peroxide catabolic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0008385 // IkappaB kinase complex // inferred from physical interaction /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0008785 // alkyl hydroperoxide reductase activity // non-traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201620_at NM_003791 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003791.1 /DEF=Homo sapiens membrane-bound transcription factor protease, site 1 (MBTPS1), mRNA. /FEA=mRNA /GEN=MBTPS1 /PROD=site-1 protease preproprotein /DB_XREF=gi:4506774 /UG=Hs.75890 membrane-bound transcription factor protease, site 1 /FL=gb:NM_003791.1 gb:D42053.1" NM_003791 "membrane-bound transcription factor peptidase, site 1" MBTPS1 8720 NM_003791 /// NM_201268 0006508 // proteolysis // not recorded /// 0006508 // proteolysis // inferred from mutant phenotype /// 0006629 // lipid metabolic process // not recorded /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0042990 // regulation of transcription factor import into nucleus // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // not recorded /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0004252 // serine-type endopeptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201621_at NM_005380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005380.1 /DEF=Homo sapiens neuroblastoma, suppression of tumorigenicity 1 (NBL1), mRNA. /FEA=mRNA /GEN=NBL1 /PROD=neuroblastoma, suppression of tumorigenicity 1 /DB_XREF=gi:4885508 /UG=Hs.76307 neuroblastoma, suppression of tumorigenicity 1 /FL=gb:NM_005380.1 gb:D28124.1" NM_005380 "neuroblastoma 1, DAN family BMP antagonist" NBL1 4681 NM_001204084 /// NM_001204085 /// NM_001204086 /// NM_001278164 /// NM_001278165 /// NM_001278166 /// NM_005380 /// NM_182744 0007399 // nervous system development // inferred from sequence or structural similarity /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0038098 // sequestering of BMP from receptor via BMP binding // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0048263 // determination of dorsal identity // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0090027 // negative regulation of monocyte chemotaxis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred by curator /// 0005739 // mitochondrion // /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016015 // morphogen activity // inferred from sequence or structural similarity /// 0036122 // BMP binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from mutant phenotype 201622_at NM_014390 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014390.1 /DEF=Homo sapiens EBNA-2 co-activator (100kD) (p100), mRNA. /FEA=mRNA /GEN=p100 /PROD=EBNA-2 co-activator (100kD) /DB_XREF=gi:7657430 /UG=Hs.79093 EBNA-2 co-activator (100kD) /FL=gb:NM_014390.1 gb:U22055.1" NM_014390 staphylococcal nuclease and tudor domain containing 1 SND1 27044 NM_014390 "0001649 // osteoblast differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016442 // RISC complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003676 // nucleic acid binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201623_s_at BC000629 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000629.1 /DEF=Homo sapiens, Similar to aspartyl-tRNA synthetase, clone MGC:1562, mRNA, complete cds. /FEA=mRNA /PROD=Similar to aspartyl-tRNA synthetase /DB_XREF=gi:12653688 /UG=Hs.80758 aspartyl-tRNA synthetase /FL=gb:BC000629.1 gb:J05032.1 gb:NM_001349.1" BC000629 aspartyl-tRNA synthetase DARS 1615 NM_001293312 /// NM_001349 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004046 // aminoacylase activity // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201624_at NM_001349 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001349.1 /DEF=Homo sapiens aspartyl-tRNA synthetase (DARS), mRNA. /FEA=mRNA /GEN=DARS /PROD=aspartyl-tRNA synthetase /DB_XREF=gi:4557512 /UG=Hs.80758 aspartyl-tRNA synthetase /FL=gb:BC000629.1 gb:J05032.1 gb:NM_001349.1" NM_001349 aspartyl-tRNA synthetase DARS 1615 NM_001293312 /// NM_001349 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004046 // aminoacylase activity // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201625_s_at BE300521 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE300521 /FEA=EST /DB_XREF=gi:9184269 /DB_XREF=est:ba69f11.x1 /CLONE=IMAGE:2905677 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 BE300521 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 /// XM_005249542 /// XM_005249543 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 1901303 // negative regulation of cargo loading into COPII-coated vesicle // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201626_at BG292233 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG292233 /FEA=EST /DB_XREF=gi:13050848 /DB_XREF=est:602386668F1 /CLONE=IMAGE:4515521 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 BG292233 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 /// XM_005249542 /// XM_005249543 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 1901303 // negative regulation of cargo loading into COPII-coated vesicle // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201627_s_at NM_005542 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005542.1 /DEF=Homo sapiens insulin induced gene 1 (INSIG1), mRNA. /FEA=mRNA /GEN=INSIG1 /PROD=insulin induced gene 1 /DB_XREF=gi:5031800 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1" NM_005542 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 /// XM_005249542 /// XM_005249543 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 1901303 // negative regulation of cargo loading into COPII-coated vesicle // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201628_s_at NM_006570 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006570.1 /DEF=Homo sapiens Ras-related GTP-binding protein (RAGA), mRNA. /FEA=mRNA /GEN=RAGA /PROD=Ras-related GTP-binding protein /DB_XREF=gi:5729998 /UG=Hs.57304 Ras-related GTP-binding protein /FL=gb:U41654.1 gb:NM_006570.1" NM_006570 Ras-related GTP binding A RRAGA 10670 NM_006570 0006915 // apoptotic process // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0032008 // positive regulation of TOR signaling // non-traceable author statement /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0045919 // positive regulation of cytolysis // inferred from direct assay /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from direct assay 201629_s_at BE872974 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE872974 /FEA=EST /DB_XREF=gi:10321660 /DB_XREF=est:601450667F1 /CLONE=IMAGE:3854584 /UG=Hs.75393 acid phosphatase 1, soluble /FL=gb:M83653.1 gb:NM_004300.1" BE872974 "acid phosphatase 1, soluble" ACP1 52 NM_001040649 /// NM_004300 /// NM_007099 /// NM_177554 /// NR_024080 /// XR_426957 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 201630_s_at NM_004300 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004300.1 /DEF=Homo sapiens acid phosphatase 1, soluble (ACP1), transcript variant a, mRNA. /FEA=mRNA /GEN=ACP1 /PROD=acid phosphatase 1 isoform a /DB_XREF=gi:4757713 /UG=Hs.75393 acid phosphatase 1, soluble /FL=gb:M83653.1 gb:NM_004300.1" NM_004300 "acid phosphatase 1, soluble" ACP1 52 NM_001040649 /// NM_004300 /// NM_007099 /// NM_177554 /// NR_024080 /// XR_426957 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 201631_s_at NM_003897 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003897.1 /DEF=Homo sapiens immediate early response 3 (IER3), mRNA. /FEA=mRNA /GEN=IER3 /PROD=immediate early response 3 /DB_XREF=gi:4503328 /UG=Hs.76095 immediate early response 3 /FL=gb:BC000844.1 gb:BC005080.1 gb:AF083421.1 gb:NM_003897.1" NM_003897 immediate early response 3 IER3 8870 NM_003897 /// NM_052815 0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0001562 // response to protozoan // inferred from electronic annotation /// 0003085 // negative regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006282 // regulation of DNA repair // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred from electronic annotation /// 0046822 // regulation of nucleocytoplasmic transport // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201632_at NM_001414 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001414.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) (EIF2B1), mRNA. /FEA=mRNA /GEN=EIF2B1 /PROD=eukaryotic translation initiation factor 2B,subunit 1 (alpha, 26kD) /DB_XREF=gi:4503502 /UG=Hs.78592 eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) /FL=gb:NM_001414.1" NM_001414 "eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa" EIF2B1 1967 NM_001414 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // not recorded /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0019509 // L-methionine salvage from methylthioadenosine // not recorded /// 0032057 // negative regulation of translational initiation in response to stress // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051716 // cellular response to stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation /// 0046523 // S-methyl-5-thioribose-1-phosphate isomerase activity // not recorded 201633_s_at AW235051 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW235051 /FEA=EST /DB_XREF=gi:6567440 /DB_XREF=est:xn18a09.x1 /CLONE=IMAGE:2694040 /UG=Hs.79103 cytochrome b5 outer mitochondrial membrane precursor /FL=gb:BC004373.1 gb:NM_030579.1 AW235051 cytochrome b5 type B (outer mitochondrial membrane) CYB5B 80777 NM_030579 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008047 // enzyme activator activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201634_s_at NM_030579 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_030579.1 /DEF=Homo sapiens cytochrome b5 outer mitochondrial membrane precursor (CYB5-M), mRNA. /FEA=mRNA /GEN=CYB5-M /PROD=cytochrome b5 outer mitochondrial membraneprecursor /DB_XREF=gi:13385593 /UG=Hs.79103 cytochrome b5 outer mitochondrial membrane precursor /FL=gb:BC004373.1 gb:NM_030579.1" NM_030579 cytochrome b5 type B (outer mitochondrial membrane) CYB5B 80777 NM_030579 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0008047 // enzyme activator activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201635_s_at AI990766 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI990766 /FEA=EST /DB_XREF=gi:5837647 /DB_XREF=est:ws23e06.x1 /CLONE=IMAGE:2498050 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1" AI990766 "fragile X mental retardation, autosomal homolog 1" FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 /// XM_005247813 /// XM_005247814 /// XM_005247815 /// XM_005247816 /// XM_006713775 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation 0002151 // G-quadruplex RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201636_at BG025078 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG025078 /FEA=EST /DB_XREF=gi:12411309 /DB_XREF=est:602276425F1 /CLONE=IMAGE:4364070 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1" BG025078 "fragile X mental retardation, autosomal homolog 1" FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 /// XM_005247813 /// XM_005247814 /// XM_005247815 /// XM_005247816 /// XM_006713775 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation 0002151 // G-quadruplex RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201637_s_at NM_005087 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005087.1 /DEF=Homo sapiens fragile X mental retardation, autosomal homolog 1 (FXR1), mRNA. /FEA=mRNA /GEN=FXR1 /PROD=fragile X mental retardation-related protein 1 /DB_XREF=gi:4826735 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1" NM_005087 "fragile X mental retardation, autosomal homolog 1" FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 /// XM_005247813 /// XM_005247814 /// XM_005247815 /// XM_005247816 /// XM_006713775 0006915 // apoptotic process // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation 0002151 // G-quadruplex RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201638_s_at BE676642 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE676642 /FEA=EST /DB_XREF=gi:10037183 /DB_XREF=est:7f33f02.x1 /CLONE=IMAGE:3296475 /UG=Hs.83727 cleavage and polyadenylation specific factor 1, 160kD subunit /FL=gb:U37012.1 gb:AB046744.1 gb:NM_013291.1" BE676642 "cleavage and polyadenylation specific factor 1, 160kDa" CPSF1 29894 NM_013291 /// XM_006716548 /// XM_006716549 /// XM_006716550 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201639_s_at NM_013291 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013291.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 1, 160kD subunit (CPSF1), mRNA. /FEA=mRNA /GEN=CPSF1 /PROD=cleavage and polyadenylation specific factor 1,160kD subunit /DB_XREF=gi:9558724 /UG=Hs.83727 cleavage and polyadenylation specific factor 1, 160kD subunit /FL=gb:U37012.1 gb:AB046744.1 gb:NM_013291.1" NM_013291 "cleavage and polyadenylation specific factor 1, 160kDa /// microRNA 1234 /// microRNA 6849 /// microRNA 939" CPSF1 /// MIR1234 /// MIR6849 /// MIR939 29894 /// 100126351 /// 100302196 /// 102466749 NM_013291 /// NR_030635 /// NR_031600 /// NR_106908 /// XM_006716548 /// XM_006716549 /// XM_006716550 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201640_x_at NM_001294 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001294.1 /DEF=Homo sapiens cleft lip and palate associated transmembrane protein 1 (CLPTM1), mRNA. /FEA=mRNA /GEN=CLPTM1 /PROD=cleft lip and palate associated transmembraneprotein 1 /DB_XREF=gi:4502896 /UG=Hs.106671 cleft lip and palate associated transmembrane protein 1 /FL=gb:AF037339.1 gb:NM_001294.1" NM_001294 cleft lip and palate associated transmembrane protein 1 CLPTM1 1209 NM_001199468 /// NM_001282175 /// NM_001282176 /// NM_001294 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in thymus // inferred from sequence or structural similarity 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201641_at NM_004335 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004335.2 /DEF=Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. /FEA=mRNA /GEN=BST2 /PROD=bone marrow stromal cell antigen 2 /DB_XREF=gi:7262372 /UG=Hs.118110 bone marrow stromal cell antigen 2 /FL=gb:D28137.1 gb:NM_004335.2" NM_004335 bone marrow stromal cell antigen 2 BST2 684 NM_004335 0002376 // immune system process // inferred from electronic annotation /// 0002737 // negative regulation of plasmacytoid dendritic cell cytokine production // inferred from direct assay /// 0006959 // humoral immune response // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0035455 // response to interferon-alpha // inferred from sequence or structural similarity /// 0035456 // response to interferon-beta // inferred from sequence or structural similarity /// 0042113 // B cell activation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 1901253 // negative regulation of intracellular transport of viral material // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201642_at NM_005534 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005534.1 /DEF=Homo sapiens interferon gamma receptor 2 (interferon gamma transducer 1) (IFNGR2), mRNA. /FEA=mRNA /GEN=IFNGR2 /PROD=interferon gamma receptor 2 (interferon gammatransducer 1) /DB_XREF=gi:5031782 /UG=Hs.177559 interferon gamma receptor 2 (interferon gamma transducer 1) /FL=gb:BC003624.1 gb:U05875.1 gb:U05877.1 gb:NM_005534.1" NM_005534 interferon gamma receptor 2 (interferon gamma transducer 1) IFNGR2 3460 NM_005534 /// XM_005260969 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004906 // interferon-gamma receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201643_x_at NM_016604 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016604.1 /DEF=Homo sapiens putative zinc finger protein (LOC51780), mRNA. /FEA=mRNA /GEN=LOC51780 /PROD=putative zinc finger protein /DB_XREF=gi:7706598 /UG=Hs.24125 putative zinc finger protein /FL=gb:AF251039.1 gb:NM_016604.1" NM_016604 lysine (K)-specific demethylase 3B KDM3B 51780 NM_016604 /// XM_005272018 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 201644_at NM_003313 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003313.2 /DEF=Homo sapiens tissue specific transplantation antigen P35B (TSTA3), mRNA. /FEA=mRNA /GEN=TSTA3 /PROD=tissue specific transplantation antigen P35B /DB_XREF=gi:6598326 /UG=Hs.264428 tissue specific transplantation antigen P35B /FL=gb:BC001941.1 gb:U58766.1 gb:NM_003313.2" NM_003313 tissue specific transplantation antigen P35B TSTA3 7264 NM_003313 /// XM_005251050 /// XM_005251051 /// XM_005251052 /// XM_006725093 /// XM_006725094 0007159 // leukocyte cell-cell adhesion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019673 // GDP-mannose metabolic process // inferred from direct assay /// 0019835 // cytolysis // inferred from electronic annotation /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from direct assay /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // inferred from electronic annotation /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042356 // GDP-4-dehydro-D-rhamnose reductase activity // traceable author statement /// 0050577 // GDP-L-fucose synthase activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation 201645_at NM_002160 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002160.1 /DEF=Homo sapiens hexabrachion (tenascin C, cytotactin) (HXB), mRNA. /FEA=mRNA /GEN=HXB /PROD=hexabrachion (tenascin C, cytotactin) /DB_XREF=gi:4504548 /UG=Hs.289114 hexabrachion (tenascin C, cytotactin) /FL=gb:M55618.1 gb:NM_002160.1" NM_002160 tenascin C TNC 3371 NM_002160 /// XM_005251972 /// XM_005251973 /// XM_005251974 /// XM_005251975 /// XM_006717096 /// XM_006717097 /// XM_006717098 /// XM_006717099 /// XM_006717100 /// XM_006717101 0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0060447 // bud outgrowth involved in lung branching // inferred from electronic annotation /// 0060739 // mesenchymal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation /// 0071799 // cellular response to prostaglandin D stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation /// 0045545 // syndecan binding // inferred from physical interaction 201646_at AA885297 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA885297 /FEA=EST /DB_XREF=gi:2994374 /DB_XREF=est:al58h03.s1 /CLONE=IMAGE:1461557 /UG=Hs.323567 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) /FL=gb:D12676.1 gb:NM_005506.1" AA885297 "scavenger receptor class B, member 2" SCARB2 950 NM_001204255 /// NM_005506 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201647_s_at NM_005506 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005506.1 /DEF=Homo sapiens CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) (CD36L2), mRNA. /FEA=mRNA /GEN=CD36L2 /PROD=CD36 antigen (collagen type I receptor,thrombospondin receptor)-like 2 (lysosomal integralmembrane protein II) /DB_XREF=gi:5031630 /UG=Hs.323567 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) /FL=gb:D12676.1 gb:NM_005506.1" NM_005506 "scavenger receptor class B, member 2" SCARB2 950 NM_001204255 /// NM_005506 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 201648_at AL039831 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL039831 /FEA=EST /DB_XREF=gi:5935215 /DB_XREF=est:DKFZp434D1112_s1 /CLONE=DKFZp434D1112 /UG=Hs.50651 Janus kinase 1 (a protein tyrosine kinase) /FL=gb:M64174.1 gb:NM_002227.1 AL039831 Janus kinase 1 JAK1 3716 NM_002227 /// XM_005270841 /// XM_006710624 0006468 // protein phosphorylation // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038110 // interleukin-2-mediated signaling pathway // inferred from direct assay /// 0046677 // response to antibiotic // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005131 // growth hormone receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation" 201649_at NM_004223 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004223.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2L 6 (UBE2L6), mRNA. /FEA=mRNA /GEN=UBE2L6 /PROD=ubiquitin-conjugating enzyme E2L 6 /DB_XREF=gi:4759281 /UG=Hs.169895 ubiquitin-conjugating enzyme E2L 6 /FL=gb:AF031141.1 gb:AF061736.1 gb:NM_004223.1" NM_004223 ubiquitin-conjugating enzyme E2L 6 UBE2L6 9246 NM_004223 /// NM_198183 0006464 // cellular protein modification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019941 // modification-dependent protein catabolic process // inferred from electronic annotation /// 0032020 // ISG15-protein conjugation // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0042296 // ISG15 ligase activity // inferred from electronic annotation 201650_at NM_002276 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002276.1 /DEF=Homo sapiens keratin 19 (KRT19), mRNA. /FEA=mRNA /GEN=KRT19 /PROD=keratin 19 /DB_XREF=gi:4504916 /UG=Hs.182265 keratin 19 /FL=gb:BC002539.1 gb:NM_002276.1" NM_002276 keratin 19 KRT19 3880 NM_002276 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from expression pattern /// 0045214 // sarcomere organization // inferred from direct assay /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation 0005882 // intermediate filament // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 201651_s_at NM_007229 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007229.1 /DEF=Homo sapiens protein kinase C and casein kinase substrate in neurons 2 (PACSIN2), mRNA. /FEA=mRNA /GEN=PACSIN2 /PROD=protein kinase C and casein kinase substrate inneurons 2 /DB_XREF=gi:6005825 /UG=Hs.18842 protein kinase C and casein kinase substrate in neurons 2 /FL=gb:AF128536.1 gb:NM_007229.1" NM_007229 protein kinase C and casein kinase substrate in neurons 2 PACSIN2 11252 NM_001184970 /// NM_001184971 /// NM_007229 /// XM_005261319 /// XM_006724117 /// XM_006724118 /// XM_006724119 /// XM_006724120 0006897 // endocytosis // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0045806 // negative regulation of endocytosis // inferred from electronic annotation /// 0048858 // cell projection morphogenesis // inferred from sequence or structural similarity /// 0070836 // caveola assembly // inferred from mutant phenotype /// 0072584 // caveolin-mediated endocytosis // inferred from mutant phenotype /// 0097320 // membrane tubulation // inferred from direct assay /// 0097320 // membrane tubulation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070300 // phosphatidic acid binding // inferred from direct assay 201652_at NM_006837 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006837.1 /DEF=Homo sapiens COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5 (COPS5), mRNA. /FEA=mRNA /GEN=COPS5 /PROD=COP9 (constitutive photomorphogenic,Arabidopsis, homolog) subunit 5 /DB_XREF=gi:5803045 /UG=Hs.198767 COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5 /FL=gb:BC001187.1 gb:BC001859.1 gb:U65928.1 gb:U70734.1 gb:NM_006837.1" NM_006837 COP9 signalosome subunit 5 COPS5 10987 NM_006837 0000338 // protein deneddylation // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0010388 // cullin deneddylation // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1990182 // exosomal secretion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0008021 // synaptic vesicle // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // traceable author statement /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201653_at NM_005776 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005776.1 /DEF=Homo sapiens cornichon-like (CNIL), mRNA. /FEA=mRNA /GEN=CNIL /PROD=cornichon-like /DB_XREF=gi:5031638 /UG=Hs.201673 cornichon-like /FL=gb:AF104398.1 gb:AF070654.1 gb:AF031379.1 gb:NM_005776.1" NM_005776 cornichon family AMPA receptor auxiliary protein 1 CNIH1 10175 NM_001009551 /// NM_005776 /// XR_245653 0006810 // transport // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201654_s_at AI991033 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI991033 /FEA=EST /DB_XREF=gi:5837930 /DB_XREF=est:wu36a08.x1 /CLONE=IMAGE:2522102 /UG=Hs.211573 heparan sulfate proteoglycan 2 (perlecan) /FL=gb:M85289.1 gb:NM_005529.2 AI991033 heparan sulfate proteoglycan 2 HSPG2 3339 NM_001291860 /// NM_005529 /// XM_005245863 /// XM_006710594 /// XM_006710595 /// XM_006710596 /// XM_006710597 /// XM_006710598 "0001523 // retinoid metabolic process // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201655_s_at M85289 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M85289.1 /DEF=Human heparan sulfate proteoglycan (HSPG2) mRNA, complete cds. /FEA=mRNA /GEN=HSPG2 /PROD=heparan sulfate proteoglycan /DB_XREF=gi:184426 /UG=Hs.211573 heparan sulfate proteoglycan 2 (perlecan) /FL=gb:M85289.1 gb:NM_005529.2" M85289 heparan sulfate proteoglycan 2 HSPG2 3339 NM_001291860 /// NM_005529 /// XM_005245863 /// XM_006710594 /// XM_006710595 /// XM_006710596 /// XM_006710597 /// XM_006710598 "0001523 // retinoid metabolic process // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005605 // basal lamina // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201656_at NM_000210 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000210.1 /DEF=Homo sapiens integrin, alpha 6 (ITGA6), mRNA. /FEA=mRNA /GEN=ITGA6 /PROD=integrin alpha chain, alpha 6 /DB_XREF=gi:4557674 /UG=Hs.227730 integrin, alpha 6 /FL=gb:NM_000210.1" NM_000210 "integrin, alpha 6" ITGA6 3655 NM_000210 /// NM_001079818 /// XM_006712510 /// XM_006712511 0007044 // cell-substrate junction assembly // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0034676 // integrin alpha6-beta4 complex // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201657_at BE890745 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE890745 /FEA=EST /DB_XREF=gi:10349375 /DB_XREF=est:601431177F1 /CLONE=IMAGE:3916507 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 BE890745 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 /// XM_005268869 "0006184 // GTP catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201658_at AU151560 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU151560 /FEA=EST /DB_XREF=gi:11013081 /DB_XREF=est:AU151560 /CLONE=NT2RP2005555 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 AU151560 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 /// XM_005268869 "0006184 // GTP catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201659_s_at NM_001177 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001177.2 /DEF=Homo sapiens ADP-ribosylation factor-like 1 (ARL1), mRNA. /FEA=mRNA /GEN=ARL1 /PROD=ADP-ribosylation factor-like 1 /DB_XREF=gi:4755126 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1" NM_001177 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 /// XM_005268869 "0006184 // GTP catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from direct assay /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0048193 // Golgi vesicle transport // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008047 // enzyme activator activity // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201660_at AL525798 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL525798 /FEA=EST /DB_XREF=gi:12789291 /DB_XREF=est:AL525798 /CLONE=CS0DC013YB08 (5 prime) /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1" AL525798 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0042998 // positive regulation of Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from mutant phenotype /// 2001247 // positive regulation of phosphatidylcholine biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 201661_s_at NM_004457 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004457.2 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 3 (FACL3), mRNA. /FEA=mRNA /GEN=FACL3 /PROD=long-chain fatty-acid-Coenzyme A ligase 3 /DB_XREF=gi:12669907 /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1" NM_004457 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0042998 // positive regulation of Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from mutant phenotype /// 2001247 // positive regulation of phosphatidylcholine biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 201662_s_at D89053 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D89053.1 /DEF=Homo sapiens mRNA for Acyl-CoA synthetase 3, complete cds. /FEA=mRNA /PROD=Acyl-CoA synthetase 3 /DB_XREF=gi:4165017 /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1" D89053 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0042998 // positive regulation of Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0051047 // positive regulation of secretion // inferred from mutant phenotype /// 2001247 // positive regulation of phosphatidylcholine biosynthetic process // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 201663_s_at NM_005496 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005496.1 /DEF=Homo sapiens chromosome-associated polypeptide C (CAP-C), mRNA. /FEA=mRNA /GEN=CAP-C /PROD=chromosome-associated polypeptide C /DB_XREF=gi:4885112 /UG=Hs.50758 SMC4 (structural maintenance of chromosomes 4, yeast)-like 1 /FL=gb:AB019987.1 gb:NM_005496.1 gb:AL136877.1" NM_005496 structural maintenance of chromosomes 4 SMC4 10051 NM_001002799 /// NM_001002800 /// NM_001288753 /// NM_005496 /// XM_006713459 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000796 // condensin complex // inferred from direct assay /// 0000796 // condensin complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201664_at AL136877 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AL136877.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F205 (from clone DKFZp434F205); complete cds. /FEA=mRNA /GEN=DKFZp434F205 /PROD=hypothetical protein /DB_XREF=gi:6807670 /UG=Hs.50758 SMC4 (structural maintenance of chromosomes 4, yeast)-like 1 /FL=gb:AB019987.1 gb:NM_005496.1 gb:AL136877.1" AL136877 structural maintenance of chromosomes 4 SMC4 10051 NM_001002799 /// NM_001002800 /// NM_001288753 /// NM_005496 /// XM_006713459 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000796 // condensin complex // inferred from direct assay /// 0000796 // condensin complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201665_x_at NM_001021 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001021.1 /DEF=Homo sapiens ribosomal protein S17 (RPS17), mRNA. /FEA=mRNA /GEN=RPS17 /PROD=ribosomal protein S17 /DB_XREF=gi:4506692 /UG=Hs.5174 ribosomal protein S17 /FL=gb:M13932.1 gb:NM_001021.1" NM_001021 ribosomal protein S17 RPS17 6218 NM_001021 /// NM_001199057 /// NR_111943 /// NR_111944 "0000028 // ribosomal small subunit assembly // not recorded /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // not recorded /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201666_at NM_003254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003254.1 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) (TIMP1), mRNA. /FEA=mRNA /GEN=TIMP1 /PROD=tissue inhibitor of metalloproteinase 1precursor /DB_XREF=gi:4507508 /UG=Hs.5831 tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) /FL=gb:BC000866.1 gb:M12670.1 gb:M59906.1 gb:NM_003254.1" NM_003254 TIMP metallopeptidase inhibitor 1 TIMP1 7076 NM_003254 /// XM_005272645 0001775 // cell activation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0048553 // negative regulation of metalloenzyme activity // inferred from direct assay /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 1901164 // negative regulation of trophoblast cell migration // inferred from mutant phenotype /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201667_at NM_000165 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000165.2 /DEF=Homo sapiens gap junction protein, alpha 1, 43kD (connexin 43) (GJA1), mRNA. /FEA=mRNA /GEN=GJA1 /PROD=connexin 43 /DB_XREF=gi:4755136 /UG=Hs.74471 gap junction protein, alpha 1, 43kD (connexin 43) /FL=gb:M65188.1 gb:NM_000165.2" NM_000165 "gap junction protein, alpha 1, 43kDa" GJA1 2697 NM_000165 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0003104 // positive regulation of glomerular filtration // inferred from electronic annotation /// 0003158 // endothelium development // inferred from electronic annotation /// 0003294 // atrial ventricular junction remodeling // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0010232 // vascular transport // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010643 // cell communication by chemical coupling // inferred from electronic annotation /// 0010644 // cell communication by electrical coupling // inferred from direct assay /// 0010652 // positive regulation of cell communication by chemical coupling // inferred from electronic annotation /// 0015867 // ATP transport // inferred from electronic annotation /// 0016264 // gap junction assembly // traceable author statement /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0034405 // response to fluid shear stress // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045844 // positive regulation of striated muscle tissue development // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046850 // regulation of bone remodeling // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from direct assay /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060156 // milk ejection // inferred from electronic annotation /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from electronic annotation /// 0060371 // regulation of atrial cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0060373 // regulation of ventricular cardiac muscle cell membrane depolarization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061337 // cardiac conduction // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086014 // atrial cardiac muscle cell action potential // traceable author statement /// 2000810 // regulation of tight junction assembly // inferred from electronic annotation /// 2000987 // positive regulation of behavioral fear response // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005921 // gap junction // inferred from direct assay /// 0005921 // gap junction // inferred from sequence or structural similarity /// 0005922 // connexon complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from direct assay /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // traceable author statement /// 0043292 // contractile fiber // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from electronic annotation /// 0005243 // gap junction channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015075 // ion transmembrane transporter activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0071253 // connexin binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation 201668_x_at AW163148 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW163148 /FEA=EST /DB_XREF=gi:6302181 /DB_XREF=est:au92d06.y1 /CLONE=IMAGE:2783723 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1" AW163148 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0006112 // energy reserve metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201669_s_at NM_002356 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002356.4 /DEF=Homo sapiens myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) (MACS), mRNA. /FEA=mRNA /GEN=MACS /PROD=myristoylated alanine-rich protein kinase Csubstrate /DB_XREF=gi:11125771 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1" NM_002356 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0006112 // energy reserve metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201670_s_at M68956 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M68956.1 /DEF=Human myristoylated alanine-rich C-kinase substrate mRNA, complete cds. /FEA=mRNA /GEN=MACS /PROD=myristoylated alanine-rich C-kinase substrate /DB_XREF=gi:187386 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1" M68956 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0006112 // energy reserve metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201671_x_at BC003556 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003556.1 /DEF=Homo sapiens, ubiquitin specific protease 14 (tRNA-guanine transglycosylase), clone MGC:1453, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin specific protease 14 (tRNA-guaninetransglycosylase) /DB_XREF=gi:13097695 /UG=Hs.75981 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) /FL=gb:BC003556.1 gb:NM_005151.1 gb:U30888.1" BC003556 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) USP14 9097 NM_001037334 /// NM_005151 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0061136 // regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008193 // tRNA guanylyltransferase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070628 // proteasome binding // inferred from direct assay 201672_s_at NM_005151 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005151.1 /DEF=Homo sapiens ubiquitin specific protease 14 (tRNA-guanine transglycosylase) (USP14), mRNA. /FEA=mRNA /GEN=USP14 /PROD=ubiquitin specific protease 14 (tRNA-guaninetransglycosylase) /DB_XREF=gi:4827049 /UG=Hs.75981 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) /FL=gb:BC003556.1 gb:NM_005151.1 gb:U30888.1" NM_005151 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) USP14 9097 NM_001037334 /// NM_005151 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0061136 // regulation of proteasomal protein catabolic process // inferred from mutant phenotype 0000502 // proteasome complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004866 // endopeptidase inhibitor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008193 // tRNA guanylyltransferase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0070628 // proteasome binding // inferred from direct assay 201673_s_at NM_002103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002103.1 /DEF=Homo sapiens glycogen synthase 1 (muscle) (GYS1), mRNA. /FEA=mRNA /GEN=GYS1 /PROD=glycogen synthase 1 (muscle) /DB_XREF=gi:4504232 /UG=Hs.772 glycogen synthase 1 (muscle) /FL=gb:U32573.1 gb:BC002617.1 gb:J04501.1 gb:NM_002103.1" NM_002103 glycogen synthase 1 (muscle) GYS1 2997 NM_001161587 /// NM_002103 /// NR_027763 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from direct assay /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004373 // glycogen (starch) synthase activity // not recorded /// 0004373 // glycogen (starch) synthase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0061547 // glycogen synthase activity, transferring glucose-1-phosphate // not recorded" 201674_s_at BC000729 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000729.1 /DEF=Homo sapiens, A kinase (PRKA) anchor protein 1, clone MGC:1807, mRNA, complete cds. /FEA=mRNA /PROD=A kinase (PRKA) anchor protein 1 /DB_XREF=gi:12653874 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:BC000729.1 gb:NM_003488.1" BC000729 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_001242902 /// NM_001242903 /// NM_003488 /// NM_139275 /// XM_005257707 /// XM_005257709 /// XM_006722126 /// XM_006722127 /// XR_243684 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201675_at NM_003488 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003488.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 1 (AKAP1), mRNA. /FEA=mRNA /GEN=AKAP1 /PROD=A kinase (PRKA) anchor protein 1 /DB_XREF=gi:4502014 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:BC000729.1 gb:NM_003488.1" NM_003488 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_001242902 /// NM_001242903 /// NM_003488 /// NM_139275 /// XM_005257707 /// XM_005257709 /// XM_006722126 /// XM_006722127 /// XR_243684 0007596 // blood coagulation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201676_x_at NM_002786 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002786.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1), mRNA. /FEA=mRNA /GEN=PSMA1 /PROD=proteasome (prosome, macropain) subunit, alphatype, 1 /DB_XREF=gi:4506178 /UG=Hs.82159 proteasome (prosome, macropain) subunit, alpha type, 1 /FL=gb:BC002577.1 gb:NM_002786.1" NM_002786 "proteasome (prosome, macropain) subunit, alpha type, 1" PSMA1 5682 NM_001143937 /// NM_002786 /// NM_148976 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" "0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0005844 // polysome // traceable author statement /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201677_at AI937543 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI937543 /FEA=EST /DB_XREF=gi:5676413 /DB_XREF=est:wp78f01.x1 /CLONE=IMAGE:2467897 /UG=Hs.110480 DC12 protein /FL=gb:AF201934.1 gb:NM_020187.1 AI937543 "5-hydroxymethylcytosine (hmC) binding, ES cell-specific" HMCES 56941 NM_001006109 /// NM_020187 /// XM_005247636 /// XM_005247637 0006508 // proteolysis // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201678_s_at NM_020187 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020187.1 /DEF=Homo sapiens DC12 protein (DC12), mRNA. /FEA=mRNA /GEN=DC12 /PROD=DC12 protein /DB_XREF=gi:9910181 /UG=Hs.110480 DC12 protein /FL=gb:AF201934.1 gb:NM_020187.1" NM_020187 "5-hydroxymethylcytosine (hmC) binding, ES cell-specific" HMCES 56941 NM_001006109 /// NM_020187 /// XM_005247636 /// XM_005247637 0006508 // proteolysis // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201679_at BE646076 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE646076 /FEA=EST /DB_XREF=gi:9970376 /DB_XREF=est:7e92g12.x1 /CLONE=IMAGE:3292678 /UG=Hs.111801 arsenate resistance protein ARS2 /FL=gb:BC000082.1 gb:AF082871.1 gb:NM_015908.1 BE646076 "serrate, RNA effector molecule" SRRT 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 /// XM_005250405 /// XM_005250406 /// XM_005250407 /// XM_005250408 /// XM_006716023 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0046685 // response to arsenic-containing substance // non-traceable author statement /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201680_x_at NM_015908 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015908.1 /DEF=Homo sapiens arsenate resistance protein ARS2 (ARS2), mRNA. /FEA=mRNA /GEN=ARS2 /PROD=arsenate resistance protein ARS2 /DB_XREF=gi:7706237 /UG=Hs.111801 arsenate resistance protein ARS2 /FL=gb:BC000082.1 gb:AF082871.1 gb:NM_015908.1" NM_015908 "serrate, RNA effector molecule" SRRT 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 /// XM_005250405 /// XM_005250406 /// XM_005250407 /// XM_005250408 /// XM_006716023 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031053 // primary miRNA processing // inferred from mutant phenotype /// 0046685 // response to arsenic-containing substance // non-traceable author statement /// 0097150 // neuronal stem cell maintenance // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201681_s_at AB011155 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB011155.1 /DEF=Homo sapiens mRNA for KIAA0583 protein, partial cds. /FEA=mRNA /GEN=KIAA0583 /PROD=KIAA0583 protein /DB_XREF=gi:3043689 /UG=Hs.170290 discs, large (Drosophila) homolog 5 /FL=gb:U61843.1 gb:NM_004747.1" AB011155 "discs, large homolog 5 (Drosophila)" DLG5 9231 NM_004747 /// XM_005270276 /// XM_006718055 /// XM_006718056 /// XM_006718057 /// XM_006725120 /// XM_006725121 /// XM_006725122 /// XM_006725123 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 201682_at NM_004279 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004279.1 /DEF=Homo sapiens peptidase (mitochondrial processing) beta (PMPCB), mRNA. /FEA=mRNA /GEN=PMPCB /PROD=peptidase (mitochondrial processing) beta /DB_XREF=gi:4758733 /UG=Hs.184211 peptidase (mitochondrial processing) beta /FL=gb:AF054182.1 gb:NM_004279.1" NM_004279 peptidase (mitochondrial processing) beta PMPCB 9512 NM_004279 /// XM_005250717 /// XM_006716181 /// XR_242267 0006508 // proteolysis // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201683_x_at BE783632 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE783632 /FEA=EST /DB_XREF=gi:10204830 /DB_XREF=est:601471206F1 /CLONE=IMAGE:3874321 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 BE783632 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201684_s_at BF001668 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF001668 /FEA=EST /DB_XREF=gi:10701943 /DB_XREF=est:7g91e03.x1 /CLONE=IMAGE:3313852 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 BF001668 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201685_s_at NM_014828 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014828.1 /DEF=Homo sapiens KIAA0737 gene product (KIAA0737), mRNA. /FEA=mRNA /GEN=KIAA0737 /PROD=KIAA0737 gene product /DB_XREF=gi:7662273 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1" NM_014828 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201686_x_at AF229254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF229254.1 /DEF=Homo sapiens clone FIF 504 fibroblast growth factor 2-interacting factor (API5) mRNA, complete cds. /FEA=mRNA /GEN=API5 /PROD=fibroblast growth factor 2-interacting factor /DB_XREF=gi:12656084 /UG=Hs.227913 API5-like 1 /FL=gb:AF229254.1 gb:NM_006595.1" AF229254 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_001243747 /// NM_006595 /// NR_024625 /// XM_006718359 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201687_s_at NM_006595 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006595.1 /DEF=Homo sapiens API5-like 1 (API5L1), mRNA. /FEA=mRNA /GEN=API5L1 /PROD=API5-like 1 /DB_XREF=gi:5729729 /UG=Hs.227913 API5-like 1 /FL=gb:AF229254.1 gb:NM_006595.1" NM_006595 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_001243747 /// NM_006595 /// NR_024625 /// XM_006718359 0006915 // apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201688_s_at BG389015 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG389015 /FEA=EST /DB_XREF=gi:13282461 /DB_XREF=est:602414790F1 /CLONE=IMAGE:4523087 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 BG389015 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201689_s_at BE974098 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE974098 /FEA=EST /DB_XREF=gi:10587434 /DB_XREF=est:601680437F1 /CLONE=IMAGE:3950697 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 BE974098 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201690_s_at AA524023 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA524023 /FEA=EST /DB_XREF=gi:2264951 /DB_XREF=est:ng32e06.s1 /CLONE=IMAGE:936514 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 AA524023 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201691_s_at NM_005079 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005079.1 /DEF=Homo sapiens tumor protein D52 (TPD52), mRNA. /FEA=mRNA /GEN=TPD52 /PROD=tumor protein D52 /DB_XREF=gi:4827037 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1" NM_005079 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_001287140 /// NM_001287142 /// NM_001287143 /// NM_001287144 /// NM_005079 /// NR_105033 /// NR_105034 /// NR_105035 /// NR_105036 /// NR_105037 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201692_at NM_005866 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005866.1 /DEF=Homo sapiens sigma receptor (SR31747 binding protein 1) (SR-BP1), mRNA. /FEA=mRNA /GEN=SR-BP1 /PROD=sigma receptor (SR31747 binding protein 1) /DB_XREF=gi:5032116 /UG=Hs.24447 sigma receptor (SR31747 binding protein 1) /FL=gb:BC004899.1 gb:U75283.1 gb:U79528.1 gb:NM_005866.1" NM_005866 sigma non-opioid intracellular receptor 1 SIGMAR1 10280 NM_001282205 /// NM_001282206 /// NM_001282207 /// NM_001282208 /// NM_001282209 /// NM_005866 /// NM_147157 /// NM_147158 /// NM_147159 /// NM_147160 /// NR_104108 0006696 // ergosterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0038003 // opioid receptor signaling pathway // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008144 // drug binding // traceable author statement 201693_s_at AV733950 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV733950 /FEA=EST /DB_XREF=gi:10851495 /DB_XREF=est:AV733950 /CLONE=cdAADG12 /UG=Hs.326035 early growth response 1 /FL=gb:M62829.1 gb:NM_001964.1 AV733950 early growth response 1 EGR1 1958 NM_001964 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033233 // regulation of protein sumoylation // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // not recorded /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048169 // regulation of long-term neuronal synaptic plasticity // not recorded /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071317 // cellular response to isoquinoline alkaloid // inferred from electronic annotation /// 0071320 // cellular response to cAMP // not recorded /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // not recorded /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0071873 // response to norepinephrine // inferred from electronic annotation /// 0072110 // glomerular mesangial cell proliferation // inferred from sequence or structural similarity /// 0072303 // positive regulation of glomerular metanephric mesangial cell proliferation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201694_s_at NM_001964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001964.1 /DEF=Homo sapiens early growth response 1 (EGR1), mRNA. /FEA=mRNA /GEN=EGR1 /PROD=early growth response 1 /DB_XREF=gi:4503492 /UG=Hs.326035 early growth response 1 /FL=gb:M62829.1 gb:NM_001964.1" NM_001964 early growth response 1 EGR1 1958 NM_001964 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033233 // regulation of protein sumoylation // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // not recorded /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048169 // regulation of long-term neuronal synaptic plasticity // not recorded /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071317 // cellular response to isoquinoline alkaloid // inferred from electronic annotation /// 0071320 // cellular response to cAMP // not recorded /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // not recorded /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0071873 // response to norepinephrine // inferred from electronic annotation /// 0072110 // glomerular mesangial cell proliferation // inferred from sequence or structural similarity /// 0072303 // positive regulation of glomerular metanephric mesangial cell proliferation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0000982 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201695_s_at NM_000270 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000270.1 /DEF=Homo sapiens nucleoside phosphorylase (NP), mRNA. /FEA=mRNA /GEN=NP /PROD=purine nucleoside phosphorylase /DB_XREF=gi:4557800 /UG=Hs.75514 nucleoside phosphorylase /FL=gb:NM_000270.1" NM_000270 purine nucleoside phosphorylase PNP 4860 NM_000270 0006139 // nucleobase-containing compound metabolic process // inferred from direct assay /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006148 // inosine catabolic process // inferred from direct assay /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006738 // nicotinamide riboside catabolic process // inferred from direct assay /// 0006955 // immune response // inferred from mutant phenotype /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0034356 // NAD biosynthesis via nicotinamide riboside salvage pathway // inferred from genetic interaction /// 0034418 // urate biosynthetic process // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0070970 // interleukin-2 secretion // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0001882 // nucleoside binding // inferred from direct assay /// 0002060 // purine nucleobase binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // not recorded /// 0004731 // purine-nucleoside phosphorylase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from direct assay" 201696_at NM_005626 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005626.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 4 (SFRS4), mRNA. /FEA=mRNA /GEN=SFRS4 /PROD=splicing factor, arginineserine-rich 4 /DB_XREF=gi:5032088 /UG=Hs.76122 splicing factor, arginineserine-rich 4 /FL=gb:BC002781.1 gb:L14076.1 gb:NM_005626.1" NM_005626 serine/arginine-rich splicing factor 4 SRSF4 6429 NM_005626 /// XM_006710815 /// XM_006710816 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201697_s_at NM_001379 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001379.1 /DEF=Homo sapiens DNA (cytosine-5-)-methyltransferase 1 (DNMT1), mRNA. /FEA=mRNA /GEN=DNMT1 /PROD=DNA (cytosine-5-)-methyltransferase 1 /DB_XREF=gi:4503350 /UG=Hs.77462 DNA (cytosine-5-)-methyltransferase 1 /FL=gb:NM_001379.1" NM_001379 DNA (cytosine-5-)-methyltransferase 1 DNMT1 1786 NM_001130823 /// NM_001379 /// XM_006722681 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006306 // DNA methylation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016458 // gene silencing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0090116 // C-5 methylation of cytosine // inferred from electronic annotation" 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005657 // replication fork // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0009008 // DNA-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201698_s_at NM_003769 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003769.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 9 (SFRS9), mRNA. /FEA=mRNA /GEN=SFRS9 /PROD=splicing factor, arginineserine-rich 9 /DB_XREF=gi:4506902 /UG=Hs.77608 splicing factor, arginineserine-rich 9 /FL=gb:U30825.1 gb:NM_003769.1" NM_003769 "glutamyl-tRNA(Gln) amidotransferase, subunit C /// serine/arginine-rich splicing factor 9" GATC /// SRSF9 8683 /// 283459 NM_003769 /// NM_176818 /// NR_033684 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay" 201699_at NM_002806 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002806.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 6 (PSMC6), mRNA. /FEA=mRNA /GEN=PSMC6 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 6 /DB_XREF=gi:4506214 /UG=Hs.79357 proteasome (prosome, macropain) 26S subunit, ATPase, 6 /FL=gb:BC005390.1 gb:D78275.1 gb:AF006305.1 gb:NM_002806.1" NM_002806 "proteasome (prosome, macropain) 26S subunit, ATPase, 6" PSMC6 5706 NM_002806 /// XR_245706 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred by curator /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0090261 // positive regulation of inclusion body assembly // inferred from electronic annotation" 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from electronic annotation /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement" 201700_at NM_001760 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001760.1 /DEF=Homo sapiens cyclin D3 (CCND3), mRNA. /FEA=mRNA /GEN=CCND3 /PROD=cyclin D3 /DB_XREF=gi:4502618 /UG=Hs.83173 cyclin D3 /FL=gb:M90814.1 gb:M92287.1 gb:NM_001760.1" NM_001760 cyclin D3 CCND3 896 NM_001136017 /// NM_001136125 /// NM_001136126 /// NM_001287427 /// NM_001287434 /// NM_001760 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 201701_s_at NM_006320 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006320.1 /DEF=Homo sapiens progesterone membrane binding protein (PMBP), mRNA. /FEA=mRNA /GEN=PMBP /PROD=progesterone membrane binding protein /DB_XREF=gi:5453915 /UG=Hs.9071 progesterone membrane binding protein /FL=gb:NM_006320.1" NM_006320 progesterone receptor membrane component 2 PGRMC2 10424 NM_006320 0043401 // steroid hormone mediated signaling pathway // traceable author statement 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003707 // steroid hormone receptor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 201702_s_at AI492873 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI492873 /FEA=EST /DB_XREF=gi:4393876 /DB_XREF=est:th78b05.x1 /CLONE=IMAGE:2124753 /UG=Hs.106019 protein phosphatase 1, regulatory subunit 10 /FL=gb:NM_002714.1" AI492873 "protein phosphatase 1, regulatory subunit 10" PPP1R10 5514 NM_002714 /// NR_072994 /// XM_006715130 /// XM_006715131 /// XM_006715132 /// XM_006715133 /// XM_006725489 /// XM_006725490 /// XM_006725491 /// XM_006725492 /// XM_006725703 /// XM_006725704 /// XM_006725705 /// XM_006725706 /// XM_006725820 /// XM_006725821 /// XM_006725822 /// XM_006725823 /// XM_006725912 /// XM_006725913 /// XM_006725914 /// XM_006725915 /// XM_006726005 /// XM_006726006 /// XM_006726007 /// XM_006726008 /// XM_006726100 /// XM_006726101 /// XM_006726102 /// XM_006726103 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation" 0000785 // chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201703_s_at NM_002714 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002714.1 /DEF=Homo sapiens protein phosphatase 1, regulatory subunit 10 (PPP1R10), mRNA. /FEA=mRNA /GEN=PPP1R10 /PROD=protein phosphatase 1, regulatory subunit 10 /DB_XREF=gi:4506008 /UG=Hs.106019 protein phosphatase 1, regulatory subunit 10 /FL=gb:NM_002714.1" NM_002714 "protein phosphatase 1, regulatory subunit 10" PPP1R10 5514 NM_002714 /// NR_072994 /// XM_006715130 /// XM_006715131 /// XM_006715132 /// XM_006715133 /// XM_006725489 /// XM_006725490 /// XM_006725491 /// XM_006725492 /// XM_006725703 /// XM_006725704 /// XM_006725705 /// XM_006725706 /// XM_006725820 /// XM_006725821 /// XM_006725822 /// XM_006725823 /// XM_006725912 /// XM_006725913 /// XM_006725914 /// XM_006725915 /// XM_006726005 /// XM_006726006 /// XM_006726007 /// XM_006726008 /// XM_006726100 /// XM_006726101 /// XM_006726102 /// XM_006726103 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation" 0000785 // chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201704_at NM_001247 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001247.1 /DEF=Homo sapiens ectonucleoside triphosphate diphosphohydrolase 6 (putative function) (ENTPD6), mRNA. /FEA=mRNA /GEN=ENTPD6 /PROD=ectonucleoside triphosphate diphosphohydrolase 6(putative function) /DB_XREF=gi:4557422 /UG=Hs.12330 ectonucleoside triphosphate diphosphohydrolase 6 (putative function) /FL=gb:AF039916.1 gb:NM_001247.1" NM_001247 ectonucleoside triphosphate diphosphohydrolase 6 (putative) ENTPD6 955 NM_001114089 /// NM_001247 /// XM_005260878 /// XM_005260881 /// XM_005260882 /// XM_005260883 /// XM_005260884 /// XM_005260885 /// XM_005260886 /// XM_005260887 /// XM_006723665 /// XM_006723666 0008152 // metabolic process // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0008894 // guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from electronic annotation" 201705_at NM_002811 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002811.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) (PSMD7), mRNA. /FEA=mRNA /GEN=PSMD7 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 7 (Mov34 homolog) /DB_XREF=gi:4506230 /UG=Hs.155543 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) /FL=gb:NM_002811.1 gb:D50063.1" NM_002811 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 7" PSMD7 5713 NM_002811 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201706_s_at BC000496 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000496.1 /DEF=Homo sapiens, peroxisomal farnesylated protein, clone MGC:8403, mRNA, complete cds. /FEA=mRNA /PROD=peroxisomal farnesylated protein /DB_XREF=gi:12653448 /UG=Hs.168670 peroxisomal farnesylated protein /FL=gb:BC000496.1 gb:NM_002857.1 gb:AB018541.1" BC000496 peroxisomal biogenesis factor 19 PEX19 5824 NM_001131039 /// NM_001193644 /// NM_002857 /// NR_036492 /// NR_036493 0006625 // protein targeting to peroxisome // inferred from direct assay /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0007031 // peroxisome organization // non-traceable author statement /// 0016557 // peroxisome membrane biogenesis // inferred from direct assay /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0045046 // protein import into peroxisome membrane // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 0072663 // establishment of protein localization to peroxisome // inferred from mutant phenotype /// 1900131 // negative regulation of lipid binding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0036105 // peroxisome membrane class-1 targeting sequence binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 201707_at NM_002857 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002857.1 /DEF=Homo sapiens peroxisomal farnesylated protein (PXF), mRNA. /FEA=mRNA /GEN=PXF /PROD=peroxisomal farnesylated protein /DB_XREF=gi:4506338 /UG=Hs.168670 peroxisomal farnesylated protein /FL=gb:BC000496.1 gb:NM_002857.1 gb:AB018541.1" NM_002857 peroxisomal biogenesis factor 19 PEX19 5824 NM_001131039 /// NM_001193644 /// NM_002857 /// NR_036492 /// NR_036493 0006625 // protein targeting to peroxisome // inferred from direct assay /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0007031 // peroxisome organization // non-traceable author statement /// 0016557 // peroxisome membrane biogenesis // inferred from direct assay /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0045046 // protein import into peroxisome membrane // inferred from direct assay /// 0050821 // protein stabilization // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 0072663 // establishment of protein localization to peroxisome // inferred from mutant phenotype /// 1900131 // negative regulation of lipid binding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0036105 // peroxisome membrane class-1 targeting sequence binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 201708_s_at AW083371 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW083371 /FEA=EST /DB_XREF=gi:6038609 /DB_XREF=est:xc09g02.x1 /CLONE=IMAGE:2583794 /UG=Hs.173878 NIPSNAP, C. elegans, homolog 1 /FL=gb:BC002371.1 gb:NM_003634.1" AW083371 nipsnap homolog 1 (C. elegans) NIPSNAP1 8508 NM_001202502 /// NM_003634 /// XM_005261789 0019233 // sensory perception of pain // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0097060 // synaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from electronic annotation 201709_s_at NM_003634 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003634.1 /DEF=Homo sapiens NIPSNAP, C. elegans, homolog 1 (NIPSNAP1), mRNA. /FEA=mRNA /GEN=NIPSNAP1 /PROD=NIPSNAP, C. elegans, homolog 1 /DB_XREF=gi:4505398 /UG=Hs.173878 NIPSNAP, C. elegans, homolog 1 /FL=gb:BC002371.1 gb:NM_003634.1" NM_003634 nipsnap homolog 1 (C. elegans) NIPSNAP1 8508 NM_001202502 /// NM_003634 /// XM_005261789 0019233 // sensory perception of pain // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0097060 // synaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0042165 // neurotransmitter binding // inferred from electronic annotation 201710_at NM_002466 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002466.1 /DEF=Homo sapiens v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2), mRNA. /FEA=mRNA /GEN=MYBL2 /PROD=v-myb avian myeloblastosis viral oncogenehomolog-like 2 /DB_XREF=gi:4505292 /UG=Hs.179718 v-myb avian myeloblastosis viral oncogene homolog-like 2 /FL=gb:NM_002466.1" NM_002466 v-myb avian myeloblastosis viral oncogene homolog-like 2 MYBL2 4605 NM_001278610 /// NM_002466 "0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051726 // regulation of cell cycle // traceable author statement /// 0090307 // spindle assembly involved in mitosis // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0031523 // Myb complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201711_x_at AI681120 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI681120 /FEA=EST /DB_XREF=gi:4891302 /DB_XREF=est:tx44b06.x1 /CLONE=IMAGE:2272403 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1 AI681120 RAN binding protein 2 RANBP2 5903 NM_006267 /// XM_005264002 /// XM_005264003 /// XM_005264004 /// XM_005264005 /// XM_005264006 /// XM_005264007 0000278 // mitotic cell cycle // traceable author statement /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201712_s_at NM_006267 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006267.2 /DEF=Homo sapiens RAN binding protein 2 (RANBP2), mRNA. /FEA=mRNA /GEN=RANBP2 /PROD=RAN binding protein 2 /DB_XREF=gi:6382078 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1" NM_006267 RAN binding protein 2 RANBP2 5903 NM_006267 /// XM_005264002 /// XM_005264003 /// XM_005264004 /// XM_005264005 /// XM_005264006 /// XM_005264007 0000278 // mitotic cell cycle // traceable author statement /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201713_s_at D42063 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D42063.1 /DEF=Human mRNA for RanBP2 (Ran-binding protein 2), complete cds. /FEA=mRNA /PROD=RanBP2 (Ran-binding protein 2) /DB_XREF=gi:924266 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1" D42063 RAN binding protein 2 RANBP2 5903 NM_006267 /// XM_005264002 /// XM_005264003 /// XM_005264004 /// XM_005264005 /// XM_005264006 /// XM_005264007 0000278 // mitotic cell cycle // traceable author statement /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0090526 // regulation of gluconeogenesis involved in cellular glucose homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201714_at NM_001070 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001070.1 /DEF=Homo sapiens tubulin, gamma 1 (TUBG1), mRNA. /FEA=mRNA /GEN=TUBG1 /PROD=tubulin, gamma 1 /DB_XREF=gi:4507730 /UG=Hs.21635 tubulin, gamma 1 /FL=gb:BC000619.1 gb:M61764.1 gb:NM_001070.1" NM_001070 "tubulin, gamma 1" TUBG1 7283 NM_001070 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000212 // meiotic spindle organization // inferred from sequence or structural similarity /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007020 // microtubule nucleation // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from sequence or structural similarity /// 0000930 // gamma-tubulin complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from electronic annotation /// 0036064 // ciliary basal body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201715_s_at NM_014977 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014977.1 /DEF=Homo sapiens KIAA0670 proteinacinus (KIAA0670), mRNA. /FEA=mRNA /GEN=KIAA0670 /PROD=KIAA0670 proteinacinus /DB_XREF=gi:7662237 /UG=Hs.227133 KIAA0670 proteinacinus /FL=gb:AF124726.1 gb:NM_014977.1" NM_014977 apoptotic chromatin condensation inducer 1 ACIN1 22985 NM_001164814 /// NM_001164815 /// NM_001164816 /// NM_001164817 /// NM_014977 /// XM_005267415 /// XM_005267416 /// XM_005267418 /// XM_006720081 /// XR_429295 /// XR_429296 /// XR_429297 "0006200 // ATP catabolic process // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from expression pattern /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045657 // positive regulation of monocyte differentiation // inferred from expression pattern /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0061574 // ASAP complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // non-traceable author statement /// 0019899 // enzyme binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201716_at NM_003099 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003099.1 /DEF=Homo sapiens sorting nexin 1 (SNX1), mRNA. /FEA=mRNA /GEN=SNX1 /PROD=sorting nexin 1 /DB_XREF=gi:4507138 /UG=Hs.75283 sorting nexin 1 /FL=gb:BC000357.1 gb:U53225.1 gb:AF065483.1 gb:NM_003099.1" NM_003099 sorting nexin 1 SNX1 6642 NM_001242933 /// NM_003099 /// NM_148955 /// NM_152826 /// XM_005254610 /// XM_005254611 "0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from mutant phenotype /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay 201717_at NM_004927 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004927.1 /DEF=Homo sapiens chromosome 11 open reading frame 4 (C11ORF4), mRNA. /FEA=mRNA /GEN=C11ORF4 /PROD=chromosome 11 open reading frame 4 /DB_XREF=gi:4826648 /UG=Hs.75859 chromosome 11 open reading frame 4 /FL=gb:U39400.1 gb:BC004378.1 gb:NM_004927.1" NM_004927 mitochondrial ribosomal protein L49 MRPL49 740 NM_004927 /// NR_037567 /// NR_037568 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201718_s_at BF511685 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF511685 /FEA=EST /DB_XREF=gi:11594983 /DB_XREF=est:UI-H-BI4-aom-c-09-0-UI.s1 /CLONE=IMAGE:3085432 /UG=Hs.7857 erythrocyte membrane protein band 4.1-like 2 /FL=gb:AF027299.1 gb:NM_001431.1 BF511685 erythrocyte membrane protein band 4.1-like 2 EPB41L2 2037 NM_001135554 /// NM_001135555 /// NM_001199388 /// NM_001199389 /// NM_001252660 /// NM_001431 /// XM_005266840 /// XM_005266841 /// XM_006715356 /// XM_006715357 /// XM_006715358 /// XM_006715359 /// XM_006715360 /// XM_006715361 /// XM_006715362 /// XM_006715363 /// XM_006715364 /// XM_006715365 /// XM_006715366 /// XM_006715367 /// XM_006715368 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0042731 // PH domain binding // inferred from electronic annotation 201719_s_at NM_001431 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001431.1 /DEF=Homo sapiens erythrocyte membrane protein band 4.1-like 2 (EPB41L2), mRNA. /FEA=mRNA /GEN=EPB41L2 /PROD=erythrocyte membrane protein band 4.1-like 2 /DB_XREF=gi:4503578 /UG=Hs.7857 erythrocyte membrane protein band 4.1-like 2 /FL=gb:AF027299.1 gb:NM_001431.1" NM_001431 erythrocyte membrane protein band 4.1-like 2 EPB41L2 2037 NM_001135554 /// NM_001135555 /// NM_001199388 /// NM_001199389 /// NM_001252660 /// NM_001431 /// XM_005266840 /// XM_005266841 /// XM_006715356 /// XM_006715357 /// XM_006715358 /// XM_006715359 /// XM_006715360 /// XM_006715361 /// XM_006715362 /// XM_006715363 /// XM_006715364 /// XM_006715365 /// XM_006715366 /// XM_006715367 /// XM_006715368 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030507 // spectrin binding // inferred from electronic annotation /// 0042731 // PH domain binding // inferred from electronic annotation 201720_s_at AI589086 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI589086 /FEA=EST /DB_XREF=gi:4598134 /DB_XREF=est:tf80g10.x1 /CLONE=IMAGE:2105634 /UG=Hs.79356 Lysosomal-associated multispanning membrane protein-5 /FL=gb:U51240.1 gb:NM_006762.1 gb:U30498.1 AI589086 lysosomal protein transmembrane 5 LAPTM5 7805 NM_006762 0006810 // transport // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201721_s_at NM_006762 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006762.1 /DEF=Homo sapiens Lysosomal-associated multispanning membrane protein-5 (LAPTM5), mRNA. /FEA=mRNA /GEN=LAPTM5 /PROD=Lysosomal-associated multispanning membraneprotein-5 /DB_XREF=gi:5803055 /UG=Hs.79356 Lysosomal-associated multispanning membrane protein-5 /FL=gb:U51240.1 gb:NM_006762.1 gb:U30498.1" NM_006762 lysosomal protein transmembrane 5 LAPTM5 7805 NM_006762 0006810 // transport // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201722_s_at AV692127 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV692127 /FEA=EST /DB_XREF=gi:10293990 /DB_XREF=est:AV692127 /CLONE=GKCAOB04 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2 AV692127 polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 2589 NM_020474 /// XM_005258239 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 201723_s_at U41514 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U41514.1 /DEF=Human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA, complete cds. /FEA=mRNA /PROD=UDP-GalNAc:polypeptideN-acetylgalactosaminyltransferase /DB_XREF=gi:1136284 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2" U41514 polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 2589 NM_020474 /// XM_005258239 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 201724_s_at NM_020474 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020474.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (GALNT1), mRNA. /FEA=mRNA /GEN=GALNT1 /PROD=polypeptide N-acetylgalactosaminyltransferase 1 /DB_XREF=gi:13124890 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2" NM_020474 polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 2589 NM_020474 /// XM_005258239 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 201725_at NM_006023 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006023.1 /DEF=Homo sapiens D123 gene product (D123), mRNA. /FEA=mRNA /GEN=D123 /PROD=D123 gene product /DB_XREF=gi:5174422 /UG=Hs.82043 D123 gene product /FL=gb:BC001600.1 gb:D14878.1 gb:U27112.1 gb:NM_006023.1" NM_006023 cell division cycle 123 CDC123 8872 NM_006023 /// XM_005252638 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 201726_at BC003376 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003376.1 /DEF=Homo sapiens, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), clone MGC:5084, mRNA, complete cds. /FEA=mRNA /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 1 (Hu antigen R) /DB_XREF=gi:13097227 /UG=Hs.12379 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) /FL=gb:U38175.1 gb:BC003376.1 gb:NM_001419.1" BC003376 ELAV like RNA binding protein 1 ELAVL1 1994 NM_001419 /// XR_430131 0006417 // regulation of translation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201727_s_at NM_001419 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001419.1 /DEF=Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mRNA. /FEA=mRNA /GEN=ELAVL1 /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 1 (Hu antigen R) /DB_XREF=gi:4503550 /UG=Hs.12379 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) /FL=gb:U38175.1 gb:BC003376.1 gb:NM_001419.1" NM_001419 ELAV like RNA binding protein 1 ELAVL1 1994 NM_001419 /// XR_430131 0006417 // regulation of translation // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from direct assay /// 0048255 // mRNA stabilization // inferred from mutant phenotype /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017091 // AU-rich element binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0035925 // mRNA 3'-UTR AU-rich region binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201728_s_at AA904674 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA904674 /FEA=EST /DB_XREF=gi:3039797 /DB_XREF=est:oj73f02.s1 /CLONE=IMAGE:1503963 /UG=Hs.151761 KIAA0100 gene product /FL=gb:D43947.1 gb:NM_014680.1 AA904674 KIAA0100 KIAA0100 9703 NM_014680 /// XM_005258073 /// XM_006722198 /// XR_429933 0005576 // extracellular region // inferred from electronic annotation 201729_s_at NM_014680 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014680.1 /DEF=Homo sapiens KIAA0100 gene product (KIAA0100), mRNA. /FEA=mRNA /GEN=KIAA0100 /PROD=KIAA0100 gene product /DB_XREF=gi:7661903 /UG=Hs.151761 KIAA0100 gene product /FL=gb:D43947.1 gb:NM_014680.1" NM_014680 KIAA0100 KIAA0100 9703 NM_014680 /// XM_005258073 /// XM_006722198 /// XR_429933 0005576 // extracellular region // inferred from electronic annotation 201730_s_at BF110993 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF110993 /FEA=EST /DB_XREF=gi:10940683 /DB_XREF=est:7n42e09.x1 /CLONE=IMAGE:3567448 /UG=Hs.169750 translocated promoter region (to activated MET oncogene) /FL=gb:NM_003292.1 BF110993 "translocated promoter region, nuclear basket protein" TPR 7175 NM_003292 /// XM_005245471 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000189 // MAPK import into nucleus // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006404 // RNA import into nucleus // inferred from direct assay /// 0006405 // RNA export from nucleus // inferred from mutant phenotype /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006606 // protein import into nucleus // inferred from mutant phenotype /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008645 // hexose transport // traceable author statement /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0010827 // regulation of glucose transport // traceable author statement /// 0010965 // regulation of mitotic sister chromatid separation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031453 // positive regulation of heterochromatin assembly // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031990 // mRNA export from nucleus in response to heat stress // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from sequence or structural similarity /// 0042306 // regulation of protein import into nucleus // inferred from mutant phenotype /// 0042307 // positive regulation of protein import into nucleus // inferred from mutant phenotype /// 0043578 // nuclear matrix organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // inferred from mutant phenotype /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046827 // positive regulation of protein export from nucleus // inferred from sequence or structural similarity /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0046832 // negative regulation of RNA export from nucleus // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 1901673 // regulation of spindle assembly involved in mitosis // inferred from mutant phenotype" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0009318 // exodeoxyribonuclease VII complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from mutant phenotype /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008855 // exodeoxyribonuclease VII activity // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043495 // protein anchor // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay 201731_s_at NM_003292 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003292.1 /DEF=Homo sapiens translocated promoter region (to activated MET oncogene) (TPR), mRNA. /FEA=mRNA /GEN=TPR /PROD=translocated promoter region (to activated METoncogene) /DB_XREF=gi:4507658 /UG=Hs.169750 translocated promoter region (to activated MET oncogene) /FL=gb:NM_003292.1" NM_003292 "translocated promoter region, nuclear basket protein" TPR 7175 NM_003292 /// XM_005245471 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000189 // MAPK import into nucleus // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000738 // DNA catabolic process, exonucleolytic // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0006404 // RNA import into nucleus // inferred from direct assay /// 0006405 // RNA export from nucleus // inferred from mutant phenotype /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006606 // protein import into nucleus // inferred from mutant phenotype /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008645 // hexose transport // traceable author statement /// 0010793 // regulation of mRNA export from nucleus // inferred from mutant phenotype /// 0010827 // regulation of glucose transport // traceable author statement /// 0010965 // regulation of mitotic sister chromatid separation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031453 // positive regulation of heterochromatin assembly // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031990 // mRNA export from nucleus in response to heat stress // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from sequence or structural similarity /// 0042306 // regulation of protein import into nucleus // inferred from mutant phenotype /// 0042307 // positive regulation of protein import into nucleus // inferred from mutant phenotype /// 0043578 // nuclear matrix organization // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045947 // negative regulation of translational initiation // inferred from mutant phenotype /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046827 // positive regulation of protein export from nucleus // inferred from sequence or structural similarity /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0046832 // negative regulation of RNA export from nucleus // inferred from mutant phenotype /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 1901673 // regulation of spindle assembly involved in mitosis // inferred from mutant phenotype" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0009318 // exodeoxyribonuclease VII complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from mutant phenotype /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008855 // exodeoxyribonuclease VII activity // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043495 // protein anchor // inferred from mutant phenotype /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from direct assay /// 0070840 // dynein complex binding // inferred from direct assay 201732_s_at AF029346 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF029346.1 /DEF=Homo sapiens chloride channel protein 3 (CLCN3) mRNA, complete cds. /FEA=CDS /GEN=CLCN3 /PROD=chloride channel protein 3 /DB_XREF=gi:2599547 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1" AF029346 "chloride channel, voltage-sensitive 3" CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201733_at AA902971 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA902971 /FEA=EST /DB_XREF=gi:3038094 /DB_XREF=est:ok44c09.s1 /CLONE=IMAGE:1516816 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AA902971 "chloride channel, voltage-sensitive 3" CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201734_at AI760629 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI760629 /FEA=EST /DB_XREF=gi:5176296 /DB_XREF=est:wi66e06.x1 /CLONE=IMAGE:2398306 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AI760629 "chloride channel, voltage-sensitive 3" CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201735_s_at NM_001829 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001829.1 /DEF=Homo sapiens chloride channel 3 (CLCN3), mRNA. /FEA=mRNA /GEN=CLCN3 /PROD=chloride channel 3 /DB_XREF=gi:4502868 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1" NM_001829 "chloride channel, voltage-sensitive 3" CLCN3 1182 NM_001243372 /// NM_001243374 /// NM_001829 /// NM_173872 /// XM_005262726 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay 201736_s_at BF000409 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF000409 /FEA=EST /DB_XREF=gi:10700684 /DB_XREF=est:7h27h07.x1 /CLONE=IMAGE:3317245 /UG=Hs.20141 similar to S. cerevisiae SSM4 /FL=gb:AF009301.1 gb:NM_005885.1 BF000409 "membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase" 6-Mar 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201737_s_at NM_005885 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005885.1 /DEF=Homo sapiens similar to S. cerevisiae SSM4 (TEB4), mRNA. /FEA=mRNA /GEN=TEB4 /PROD=similar to S. cerevisiae SSM4 /DB_XREF=gi:5032166 /UG=Hs.20141 similar to S. cerevisiae SSM4 /FL=gb:AF009301.1 gb:NM_005885.1" NM_005885 "membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase" 6-Mar 10299 NM_001270660 /// NM_001270661 /// NM_005885 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201738_at NM_005875 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005875.1 /DEF=Homo sapiens translation factor sui1 homolog (GC20), mRNA. /FEA=mRNA /GEN=GC20 /PROD=translation factor sui1 homolog /DB_XREF=gi:5031710 /UG=Hs.21756 translation factor sui1 homolog /FL=gb:AF064607.1 gb:AF077052.1 gb:NM_005875.1 gb:AF263452.1" NM_005875 eukaryotic translation initiation factor 1B EIF1B 10289 NM_005875 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // non-traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201739_at NM_005627 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005627.1 /DEF=Homo sapiens serumglucocorticoid regulated kinase (SGK), mRNA. /FEA=mRNA /GEN=SGK /PROD=serumglucocorticoid regulated kinase /DB_XREF=gi:5032090 /UG=Hs.296323 serumglucocorticoid regulated kinase /FL=gb:BC001263.1 gb:NM_005627.1 gb:AF153609.1" NM_005627 serum/glucocorticoid regulated kinase 1 SGK1 6446 NM_001143676 /// NM_001143677 /// NM_001143678 /// NM_001291995 /// NM_005627 0001558 // regulation of cell growth // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007616 // long-term memory // traceable author statement /// 0008217 // regulation of blood pressure // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // traceable author statement /// 0032411 // positive regulation of transporter activity // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060453 // regulation of gastric acid secretion // traceable author statement /// 0070294 // renal sodium ion absorption // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // traceable author statement /// 0017081 // chloride channel regulator activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation" 201740_at NM_004551 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004551.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Q reductase) (NDUFS3), mRNA. /FEA=mRNA /GEN=NDUFS3 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 3(30kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758787 /UG=Hs.5273 NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Q reductase) /FL=gb:BC000617.1 gb:AF067139.1 gb:NM_004551.1 gb:AF100743.1" NM_004551 "NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)" NDUFS3 4722 NM_004551 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation "0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation" 201741_x_at M69040 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:M69040.1 /DEF=Human SF2p33 mRNA, complete cds. /FEA=mRNA /PROD=SF2p33 /DB_XREF=gi:338046 /UG=Hs.73737 splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) /FL=gb:M69040.1 gb:NM_006924.1" M69040 serine/arginine-rich splicing factor 1 SRSF1 6426 NM_001078166 /// NM_006924 /// NR_034041 /// XM_006722012 /// XR_429911 /// XR_429912 /// XR_429999 /// XR_430000 /// XR_430001 /// XR_430002 /// XR_433418 /// XR_433419 /// XR_433420 /// XR_433421 /// XR_433422 "0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from physical interaction /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201742_x_at NM_006924 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006924.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) (SFRS1), mRNA. /FEA=mRNA /GEN=SFRS1 /PROD=splicing factor, arginineserine-rich 1(splicing factor 2, alternate splicing factor) /DB_XREF=gi:5902075 /UG=Hs.73737 splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) /FL=gb:M69040.1 gb:NM_006924.1" NM_006924 serine/arginine-rich splicing factor 1 SRSF1 6426 NM_001078166 /// NM_006924 /// NR_034041 /// XM_006722012 /// XR_429911 /// XR_429912 /// XR_429999 /// XR_430000 /// XR_430001 /// XR_430002 /// XR_433418 /// XR_433419 /// XR_433420 /// XR_433421 /// XR_433422 "0000395 // mRNA 5'-splice site recognition // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from physical interaction /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 201743_at NM_000591 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000591.1 /DEF=Homo sapiens CD14 antigen (CD14), mRNA. /FEA=mRNA /GEN=CD14 /PROD=CD14 antigen precursor /DB_XREF=gi:4557416 /UG=Hs.75627 CD14 antigen /FL=gb:M86511.1 gb:AF097942.1 gb:NM_000591.1" NM_000591 CD14 molecule CD14 929 NM_000591 /// NM_001040021 /// NM_001174104 /// NM_001174105 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006909 // phagocytosis // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071223 // cellular response to lipoteichoic acid // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001847 // opsonin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016019 // peptidoglycan receptor activity // traceable author statement /// 0070891 // lipoteichoic acid binding // inferred from direct assay 201744_s_at NM_002345 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002345.1 /DEF=Homo sapiens lumican (LUM), mRNA. /FEA=mRNA /GEN=LUM /PROD=lumican /DB_XREF=gi:4505046 /UG=Hs.79914 lumican /FL=gb:NM_002345.1 gb:U18728.1 gb:U21128.1" NM_002345 lumican LUM 4060 NM_002345 0005975 // carbohydrate metabolic process // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0070848 // response to growth factor // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005583 // fibrillar collagen trimer // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay 201745_at NM_002822 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002822.1 /DEF=Homo sapiens protein tyrosine kinase 9 (PTK9), mRNA. /FEA=mRNA /GEN=PTK9 /PROD=protein tyrosine kinase 9 /DB_XREF=gi:4506274 /UG=Hs.82643 protein tyrosine kinase 9 /FL=gb:NM_002822.1 gb:U02680.1" NM_002822 twinfilin actin-binding protein 1 TWF1 5756 NM_001242397 /// NM_002822 /// NM_198974 /// NR_073472 /// NR_073473 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0042989 // sequestering of actin monomers // inferred from sequence or structural similarity /// 0043538 // regulation of actin phosphorylation // inferred from direct assay /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity "0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity" 201746_at NM_000546 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000546.2 /DEF=Homo sapiens tumor protein p53 (Li-Fraumeni syndrome) (TP53), mRNA. /FEA=mRNA /GEN=TP53 /PROD=tumor protein p53 /DB_XREF=gi:8400737 /UG=Hs.1846 tumor protein p53 (Li-Fraumeni syndrome) /FL=gb:AF307851.1 gb:BC003596.1 gb:M14694.1 gb:M14695.1 gb:NM_000546.2" NM_000546 tumor protein p53 TP53 7157 NM_000546 /// NM_001126112 /// NM_001126113 /// NM_001126114 /// NM_001126115 /// NM_001126116 /// NM_001126117 /// NM_001126118 /// NM_001276695 /// NM_001276696 /// NM_001276697 /// NM_001276698 /// NM_001276699 /// NM_001276760 /// NM_001276761 "0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000733 // DNA strand renaturation // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0002309 // T cell proliferation involved in immune response // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006983 // ER overload response // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0007369 // gastrulation // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from direct assay /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0009303 // rRNA transcription // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0010165 // response to X-ray // not recorded /// 0010332 // response to gamma radiation // inferred from mutant phenotype /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // not recorded /// 0031497 // chromatin assembly // inferred from direct assay /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034103 // regulation of tissue remodeling // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from direct assay /// 0034644 // cellular response to UV // not recorded /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046677 // response to antibiotic // inferred from expression pattern /// 0046902 // regulation of mitochondrial membrane permeability // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051097 // negative regulation of helicase activity // traceable author statement /// 0051262 // protein tetramerization // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0070243 // regulation of thymocyte apoptotic process // inferred from electronic annotation /// 0070245 // positive regulation of thymocyte apoptotic process // inferred from sequence or structural similarity /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0071850 // mitotic cell cycle arrest // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090343 // positive regulation of cell aging // inferred from electronic annotation /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097252 // oligodendrocyte apoptotic process // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901525 // negative regulation of macromitophagy // inferred from electronic annotation /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 2000378 // negative regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0000785 // chromatin // not recorded /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // not recorded /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0002020 // protease binding // inferred from physical interaction /// 0002039 // p53 binding // not recorded /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003682 // chromatin binding // inferred from direct assay /// 0003684 // damaged DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035033 // histone deacetylase regulator activity // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from physical interaction /// 0097371 // MDM2/MDM4 family protein binding // inferred from electronic annotation 201747_s_at AI769566 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI769566 /FEA=EST /DB_XREF=gi:5236075 /DB_XREF=est:wj24e11.x1 /CLONE=IMAGE:2403788 /UG=Hs.23978 scaffold attachment factor B /FL=gb:U72355.1 gb:NM_002967.1 AI769566 scaffold attachment factor B SAFB 6294 NM_001201338 /// NM_001201339 /// NM_001201340 /// NM_002967 /// NR_037699 /// XM_006722839 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201748_s_at NM_002967 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002967.1 /DEF=Homo sapiens scaffold attachment factor B (SAFB), mRNA. /FEA=mRNA /GEN=SAFB /PROD=scaffold attachment factor B /DB_XREF=gi:4506778 /UG=Hs.23978 scaffold attachment factor B /FL=gb:U72355.1 gb:NM_002967.1" NM_002967 scaffold attachment factor B SAFB 6294 NM_001201338 /// NM_001201339 /// NM_001201340 /// NM_002967 /// NR_037699 /// XM_006722839 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201749_at BF969352 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF969352 /FEA=EST /DB_XREF=gi:12336567 /DB_XREF=est:602271616F1 /CLONE=IMAGE:4359794 /UG=Hs.288203 endothelin converting enzyme 1 /FL=gb:NM_001397.1 gb:AB031742.1 gb:D49471.1 BF969352 endothelin converting enzyme 1 ECE1 1889 NM_001113347 /// NM_001113348 /// NM_001113349 /// NM_001397 /// XM_006710398 0001921 // positive regulation of receptor recycling // inferred from mutant phenotype /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0010814 // substance P catabolic process // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010816 // calcitonin catabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0034959 // endothelin maturation // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from direct assay /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043583 // ear development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031302 // intrinsic component of endosome membrane // traceable author statement /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201750_s_at NM_001397 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001397.1 /DEF=Homo sapiens endothelin converting enzyme 1 (ECE1), mRNA. /FEA=mRNA /GEN=ECE1 /PROD=endothelin converting enzyme 1 /DB_XREF=gi:4503442 /UG=Hs.288203 endothelin converting enzyme 1 /FL=gb:NM_001397.1 gb:AB031742.1 gb:D49471.1" NM_001397 endothelin converting enzyme 1 ECE1 1889 NM_001113347 /// NM_001113348 /// NM_001113349 /// NM_001397 /// XM_006710398 0001921 // positive regulation of receptor recycling // inferred from mutant phenotype /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0010814 // substance P catabolic process // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010816 // calcitonin catabolic process // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0034959 // endothelin maturation // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from direct assay /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043583 // ear development // inferred from mutant phenotype /// 0060037 // pharyngeal system development // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031302 // intrinsic component of endosome membrane // traceable author statement /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201751_at NM_014876 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014876.1 /DEF=Homo sapiens KIAA0063 gene product (KIAA0063), mRNA. /FEA=mRNA /GEN=KIAA0063 /PROD=KIAA0063 gene product /DB_XREF=gi:7661887 /UG=Hs.3094 KIAA0063 gene product /FL=gb:D31884.1 gb:NM_014876.1" NM_014876 Josephin domain containing 1 JOSD1 9929 NM_014876 /// XM_005261876 /// XM_005261877 /// XM_005261878 /// XM_005261879 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201752_s_at AI763123 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI763123 /FEA=EST /DB_XREF=gi:5178790 /DB_XREF=est:wi06f09.x1 /CLONE=IMAGE:2389481 /UG=Hs.324470 adducin 3 (gamma) /FL=gb:D67031.1 gb:NM_019903.1 AI763123 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 /// XM_005269529 /// XM_005269530 /// XM_005269531 /// XM_005269533 /// XM_005269534 /// XM_005269535 /// XM_006717626 /// XM_006717627 /// XM_006717628 /// XM_006717629 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 201753_s_at NM_019903 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019903.1 /DEF=Homo sapiens adducin 3 (gamma) (ADD3), transcript variant 2, mRNA. /FEA=mRNA /GEN=ADD3 /PROD=adducin 3, isoform b /DB_XREF=gi:9951926 /UG=Hs.324470 adducin 3 (gamma) /FL=gb:D67031.1 gb:NM_019903.1" NM_019903 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 /// XM_005269529 /// XM_005269530 /// XM_005269531 /// XM_005269533 /// XM_005269534 /// XM_005269535 /// XM_006717626 /// XM_006717627 /// XM_006717628 /// XM_006717629 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 201754_at NM_004374 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004374.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIc (COX6C), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX6C /PROD=cytochrome c oxidase subunit VIc /DB_XREF=gi:4758039 /UG=Hs.74649 cytochrome c oxidase subunit VIc /FL=gb:BC000187.1 gb:NM_004374.1" NM_004374 cytochrome c oxidase subunit VIc COX6C 1345 NM_004374 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201755_at NM_006739 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006739.1 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) (MCM5), mRNA. /FEA=mRNA /GEN=MCM5 /PROD=minichromosome maintenance deficient (S.cerevisiae) 5 (cell division cycle 46) /DB_XREF=gi:6981191 /UG=Hs.77171 minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) /FL=gb:D83986.1 gb:BC000142.1 gb:BC003656.1 gb:NM_006739.1" NM_006739 minichromosome maintenance complex component 5 MCM5 4174 NM_006739 /// XM_006724242 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201756_at NM_002946 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002946.1 /DEF=Homo sapiens replication protein A2 (32kD) (RPA2), mRNA. /FEA=mRNA /GEN=RPA2 /PROD=replication protein A2 (32kD) /DB_XREF=gi:4506584 /UG=Hs.79411 replication protein A2 (32kD) /FL=gb:BC001630.1 gb:J05249.1 gb:NM_002946.1" NM_002946 "replication protein A2, 32kDa" RPA2 6118 NM_001286076 /// NM_002946 /// XM_005245965 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0000730 // DNA recombinase assembly // traceable author statement /// 0006260 // DNA replication // inferred from direct assay /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from mutant phenotype /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 2000001 // regulation of DNA damage checkpoint // inferred from mutant phenotype" "0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay" 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred by curator /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from electronic annotation 201757_at NM_004552 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004552.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 5 (15kD) (NADH-coenzyme Q reductase) (NDUFS5), mRNA. /FEA=mRNA /GEN=NDUFS5 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 5(15kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758789 /UG=Hs.80595 NADH dehydrogenase (ubiquinone) Fe-S protein 5 (15kD) (NADH-coenzyme Q reductase) /FL=gb:BC001884.1 gb:AF020352.1 gb:AF047434.1 gb:NM_004552.1" NM_004552 "NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) /// ribosomal protein L10" NDUFS5 /// RPL10 4725 /// 6134 NM_001184979 /// NM_001256577 /// NM_001256580 /// NM_004552 /// NM_006013 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201758_at NM_006292 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006292.1 /DEF=Homo sapiens tumor susceptibility gene 101 (TSG101), mRNA. /FEA=mRNA /GEN=TSG101 /PROD=tumor susceptibility gene 101 /DB_XREF=gi:5454139 /UG=Hs.118910 tumor susceptibility gene 101 /FL=gb:BC002487.1 gb:U82130.1 gb:NM_006292.1" NM_006292 tumor susceptibility 101 TSG101 7251 NM_006292 /// XM_005253107 /// XM_005253108 "0001558 // regulation of cell growth // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred by curator /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from direct assay /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046755 // viral budding // inferred from mutant phenotype /// 0046755 // viral budding // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0075733 // intracellular transport of virus // traceable author statement" 0000813 // ESCRT I complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from mutant phenotype /// 0005771 // multivesicular body // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // traceable author statement /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 201759_at AW247323 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW247323 /FEA=EST /DB_XREF=gi:6590316 /DB_XREF=est:2819524.3prime /CLONE=IMAGE:2819524 /UG=Hs.12570 tubulin-specific chaperone d /FL=gb:BC003094.1 gb:AB023205.1 gb:NM_005993.2 AW247323 tubulin folding cofactor D TBCD 6904 NM_001033052 /// NM_005993 /// XM_005256396 /// XM_005256399 /// XM_005256400 /// XM_005256401 /// XM_005256402 /// XM_005256403 /// XM_005256404 /// XM_005256405 /// XM_006722290 /// XM_006722291 /// XM_006722292 /// XR_430033 0006457 // protein folding // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0034333 // adherens junction assembly // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0070830 // tight junction assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0051087 // chaperone binding // traceable author statement 201760_s_at NM_018639 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018639.1 /DEF=Homo sapiens CS box-containing WD protein (LOC55884), mRNA. /FEA=mRNA /GEN=LOC55884 /PROD=CS box-containing WD protein /DB_XREF=gi:8923880 /UG=Hs.136644 CS box-containing WD protein /FL=gb:AF229181.1 gb:AF163324.1 gb:NM_018639.1" NM_018639 WD repeat and SOCS box containing 2 WSB2 55884 NM_001278557 /// NM_001278558 /// NM_018639 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201761_at NM_006636 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006636.2 /DEF=Homo sapiens methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (MTHFD2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MTHFD2 /PROD=methylene tetrahydrofolate dehydrogenase (NAD+dependent), methenyltetrahydrofolate cyclohydrolase,precursor /DB_XREF=gi:13699869 /UG=Hs.154672 methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase /FL=gb:NM_006636.2" NM_006636 "methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" MTHFD2 10797 NM_001040409 /// NM_006636 /// NR_027405 /// XM_006711924 0006730 // one-carbon metabolic process // not recorded /// 0008152 // metabolic process // inferred from electronic annotation /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // not recorded /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // not recorded 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004329 // formate-tetrahydrofolate ligase activity // not recorded /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // not recorded /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // inferred from sequence or structural similarity /// 0004487 // methylenetetrahydrofolate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004488 // methylenetetrahydrofolate dehydrogenase (NADP+) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from direct assay 201762_s_at NM_002818 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002818.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 2 (PA28 beta) (PSME2), mRNA. /FEA=mRNA /GEN=PSME2 /PROD=proteasome (prosome, macropain) activatorsubunit 2 (PA28 beta) /DB_XREF=gi:4506236 /UG=Hs.179774 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) /FL=gb:D45248.1 gb:BC004368.1 gb:NM_002818.1" NM_002818 "microRNA 7703 /// proteasome (prosome, macropain) activator subunit 2 (PA28 beta)" MIR7703 /// PSME2 5721 /// 102465801 NM_002818 /// NR_106990 /// XM_006720212 /// XM_006720213 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201763_s_at NM_001350 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001350.1 /DEF=Homo sapiens death-associated protein 6 (DAXX), mRNA. /FEA=mRNA /GEN=DAXX /PROD=death-associated protein 6 /DB_XREF=gi:4503256 /UG=Hs.180224 death-associated protein 6 /FL=gb:AF015956.2 gb:AF039136.1 gb:AF050179.1 gb:AF097742.1 gb:AB015051.1 gb:NM_001350.1" NM_001350 death-domain associated protein DAXX 1616 NM_001141969 /// NM_001141970 /// NM_001254717 /// NM_001350 /// XM_005248860 /// XM_005275218 /// XM_005275354 "0000281 // mitotic cytokinesis // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from genetic interaction /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 1901216 // positive regulation of neuron death // inferred from genetic interaction /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // traceable author statement /// 0070603 // SWI/SNF superfamily-type complex // inferred from direct assay" 0002039 // p53 binding // inferred from physical interaction /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030295 // protein kinase activator activity // inferred from genetic interaction /// 0031072 // heat shock protein binding // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 201764_at NM_024056 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024056.1 /DEF=Homo sapiens hypothetical protein MGC5576 (MGC5576), mRNA. /FEA=mRNA /GEN=MGC5576 /PROD=hypothetical protein MGC5576 /DB_XREF=gi:13129025 /UG=Hs.103834 hypothetical protein MGC5576 /FL=gb:BC000854.1 gb:NM_024056.1" NM_024056 transmembrane protein 106C TMEM106C 79022 NM_001143841 /// NM_001143842 /// NM_001143843 /// NM_001143844 /// NM_001143845 /// NM_024056 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201765_s_at AL523158 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL523158 /FEA=EST /DB_XREF=gi:12786651 /DB_XREF=est:AL523158 /CLONE=CS0DC001YM06 (3 prime) /UG=Hs.119403 hexosaminidase A (alpha polypeptide) /FL=gb:NM_000520.2 AL523158 hexosaminidase A (alpha polypeptide) HEXA 3073 NM_000520 0001501 // skeletal system development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0042552 // myelination // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay" 201766_at AF304370 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF304370.1 /DEF=Homo sapiens putative prostate cancer susceptibility protein HPC2ELAC2 mRNA, complete cds. /FEA=mRNA /PROD=putative prostate cancer susceptibility proteinHPC2ELAC2 /DB_XREF=gi:10880932 /UG=Hs.12124 putative prostate cancer susceptibility protein /FL=gb:AF304370.1 gb:NM_018127.2 gb:BC001939.1 gb:BC004158.1" AF304370 elaC ribonuclease Z 2 ELAC2 60528 NM_001165962 /// NM_018127 /// NM_173717 "0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0072684 // mitochondrial tRNA 3'-trailer cleavage, endonucleolytic // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201767_s_at NM_018127 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018127.2 /DEF=Homo sapiens putative prostate cancer susceptibility protein (HPC2), mRNA. /FEA=mRNA /GEN=HPC2 /PROD=putative prostate cancer susceptibility protein /DB_XREF=gi:11875212 /UG=Hs.12124 putative prostate cancer susceptibility protein /FL=gb:AF304370.1 gb:NM_018127.2 gb:BC001939.1 gb:BC004158.1" NM_018127 elaC ribonuclease Z 2 ELAC2 60528 NM_001165962 /// NM_018127 /// NM_173717 "0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0072684 // mitochondrial tRNA 3'-trailer cleavage, endonucleolytic // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201768_s_at BC004467 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC004467.1 /DEF=Homo sapiens, KIAA0171 gene product, clone MGC:10257, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0171 gene product /DB_XREF=gi:13325306 /UG=Hs.155623 KIAA0171 gene product /FL=gb:D79993.1 gb:BC004467.1 gb:NM_014666.1" BC004467 clathrin interactor 1 CLINT1 9685 NM_001195555 /// NM_001195556 /// NM_014666 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction 201769_at NM_014666 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014666.1 /DEF=Homo sapiens KIAA0171 gene product (KIAA0171), mRNA. /FEA=mRNA /GEN=KIAA0171 /PROD=KIAA0171 gene product /DB_XREF=gi:7661967 /UG=Hs.155623 KIAA0171 gene product /FL=gb:D79993.1 gb:BC004467.1 gb:NM_014666.1" NM_014666 clathrin interactor 1 CLINT1 9685 NM_001195555 /// NM_001195556 /// NM_014666 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0048268 // clathrin coat assembly // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from physical interaction 201770_at NM_004596 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004596.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA. /FEA=mRNA /GEN=SNRPA /PROD=small nuclear ribonucleoprotein polypeptide A /DB_XREF=gi:4759155 /UG=Hs.173255 small nuclear ribonucleoprotein polypeptide A /FL=gb:BC000405.1 gb:NM_004596.1" NM_004596 small nuclear ribonucleoprotein polypeptide A SNRPA 6626 NM_004596 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201771_at NM_005698 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005698.1 /DEF=Homo sapiens secretory carrier membrane protein 3 (SCAMP3), mRNA. /FEA=mRNA /GEN=SCAMP3 /PROD=secretory carrier membrane protein 3 /DB_XREF=gi:5032076 /UG=Hs.200600 secretory carrier membrane protein 3 /FL=gb:BC000161.2 gb:BC005135.1 gb:AF005039.1 gb:NM_005698.1" NM_005698 secretory carrier membrane protein 3 SCAMP3 10067 NM_005698 /// NM_052837 /// XM_006711105 /// XM_006711106 /// XM_006711107 /// XM_006726206 /// XM_006726207 /// XM_006726208 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 201772_at NM_015878 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015878.1 /DEF=Homo sapiens antizyme inhibitor (LOC51582), mRNA. /FEA=mRNA /GEN=LOC51582 /PROD=antizyme inhibitor /DB_XREF=gi:7706219 /UG=Hs.223014 antizyme inhibitor /FL=gb:D88674.1 gb:NM_015878.1" NM_015878 antizyme inhibitor 1 AZIN1 51582 NM_015878 /// NM_148174 /// XM_005250969 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0042978 // ornithine decarboxylase activator activity // inferred from electronic annotation 201773_at NM_015339 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015339.1 /DEF=Homo sapiens activity-dependent neuroprotective protein (ADNP), mRNA. /FEA=mRNA /GEN=ADNP /PROD=activity-dependent neuroprotective protein /DB_XREF=gi:12229216 /UG=Hs.3657 activity-dependent neuroprotective protein /FL=gb:AF250860.1 gb:NM_015339.1" NM_015339 activity-dependent neuroprotector homeobox ADNP 23394 NM_001282531 /// NM_001282532 /// NM_015339 /// NM_181442 /// XM_006723759 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation" 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201774_s_at AK022511 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK022511.1 /DEF=Homo sapiens cDNA FLJ12449 fis, clone NT2RM1000314, highly similar to Human mRNA for KIAA0159 gene. /FEA=mRNA /DB_XREF=gi:10433940 /UG=Hs.5719 chromosome condensation-related SMC-associated protein 1 /FL=gb:NM_014865.1 gb:D63880.1" AK022511 "non-SMC condensin I complex, subunit D2" NCAPD2 9918 NM_014865 0000278 // mitotic cell cycle // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0000796 // condensin complex // inferred from direct assay /// 0000797 // condensin core heterodimer // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030117 // membrane coat // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042393 // histone binding // non-traceable author statement 201775_s_at AA676790 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA676790 /FEA=EST /DB_XREF=gi:2657312 /DB_XREF=est:zj64h12.s1 /CLONE=IMAGE:455111 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 AA676790 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201776_s_at AK001487 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK001487.1 /DEF=Homo sapiens cDNA FLJ10625 fis, clone NT2RP2005540, highly similar to Homo sapiens mRNA for KIAA0494 protein. /FEA=mRNA /DB_XREF=gi:7022773 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1" AK001487 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201777_s_at BC002525 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002525.1 /DEF=Homo sapiens, KIAA0494 gene product, clone MGC:1949, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0494 gene product /DB_XREF=gi:12803404 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1" BC002525 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201778_s_at NM_014774 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014774.1 /DEF=Homo sapiens KIAA0494 gene product (KIAA0494), mRNA. /FEA=mRNA /GEN=KIAA0494 /PROD=KIAA0494 gene product /DB_XREF=gi:7662159 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1" NM_014774 EF-hand calcium binding domain 14 EFCAB14 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201779_s_at AF070558 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF070558.1 /DEF=Homo sapiens clone 24450 RING zinc finger protein RZF mRNA, complete cds. /FEA=mRNA /PROD=RING zinc finger protein RZF /DB_XREF=gi:3387924 /UG=Hs.6900 ring finger protein 13 /FL=gb:AF037204.1 gb:AF070558.1 gb:NM_007282.1" AF070558 ring finger protein 13 RNF13 11342 NM_007282 /// NM_183381 /// NM_183382 /// NM_183383 /// NM_183384 /// XM_005247092 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201780_s_at NM_007282 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007282.1 /DEF=Homo sapiens ring finger protein 13 (RNF13), mRNA. /FEA=mRNA /GEN=RNF13 /PROD=ring finger protein 13 /DB_XREF=gi:6005863 /UG=Hs.6900 ring finger protein 13 /FL=gb:AF037204.1 gb:AF070558.1 gb:NM_007282.1" NM_007282 ring finger protein 13 RNF13 11342 NM_007282 /// NM_183381 /// NM_183382 /// NM_183383 /// NM_183384 /// XM_005247092 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201781_s_at AL558532 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL558532 /FEA=EST /DB_XREF=gi:12903142 /DB_XREF=est:AL558532 /CLONE=CS0DJ006YJ15 (5 prime) /UG=Hs.75305 aryl hydrocarbon receptor-interacting protein /FL=gb:U31913.1 gb:U78521.1 gb:NM_003977.1 AL558532 aryl hydrocarbon receptor interacting protein AIP 9049 NM_003977 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0022417 // protein maturation by protein folding // inferred from direct assay /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0036004 // GAF domain binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 201782_s_at NM_003977 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003977.1 /DEF=Homo sapiens aryl hydrocarbon receptor-interacting protein (AIP), mRNA. /FEA=mRNA /GEN=AIP /PROD=aryl hydrocarbon receptor-interacting protein /DB_XREF=gi:4502008 /UG=Hs.75305 aryl hydrocarbon receptor-interacting protein /FL=gb:U31913.1 gb:U78521.1 gb:NM_003977.1" NM_003977 aryl hydrocarbon receptor interacting protein AIP 9049 NM_003977 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0022417 // protein maturation by protein folding // inferred from direct assay /// 0051344 // negative regulation of cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0036004 // GAF domain binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 201783_s_at NM_021975 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021975.1 /DEF=Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) (RELA), mRNA. /FEA=mRNA /GEN=RELA /PROD=v-rel avian reticuloendotheliosis viral oncogenehomolog A (nuclear factor of kappa light polypeptide geneenhancer in B-cells 3 (p65)) /DB_XREF=gi:11496238 /UG=Hs.75569 v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) /FL=gb:NM_021975.1 gb:L19067.1" NM_021975 v-rel avian reticuloendotheliosis viral oncogene homolog A RELA 5970 NM_001145138 /// NM_001243984 /// NM_001243985 /// NM_021975 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001889 // liver development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006117 // acetaldehyde metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0006968 // cellular defense response // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from direct assay /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010224 // response to UV-B // inferred from direct assay /// 0014040 // positive regulation of Schwann cell differentiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050727 // regulation of inflammatory response // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051607 // defense response to virus // non-traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0070431 // nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from genetic interaction /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071316 // cellular response to nicotine // inferred from mutant phenotype /// 0071347 // cellular response to interleukin-1 // inferred from direct assay /// 0071354 // cellular response to interleukin-6 // inferred from mutant phenotype /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071375 // cellular response to peptide hormone stimulus // inferred from mutant phenotype /// 2000630 // positive regulation of miRNA metabolic process // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0042301 // phosphate ion binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0071532 // ankyrin repeat binding // inferred from electronic annotation 201784_s_at NM_014267 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014267.1 /DEF=Homo sapiens small acidic protein (IMAGE145052), mRNA. /FEA=mRNA /GEN=IMAGE145052 /PROD=small acidic protein /DB_XREF=gi:7657233 /UG=Hs.78050 small acidic protein /FL=gb:U51678.1 gb:NM_014267.1" NM_014267 chromosome 11 open reading frame 58 C11orf58 10944 NM_001142705 /// NM_014267 201785_at NM_002933 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002933.1 /DEF=Homo sapiens ribonuclease, RNase A family, 1 (pancreatic) (RNASE1), mRNA. /FEA=mRNA /GEN=RNASE1 /PROD=ribonuclease, RNase A family, 1 (pancreatic) /DB_XREF=gi:4506546 /UG=Hs.78224 ribonuclease, RNase A family, 1 (pancreatic) /FL=gb:BC005324.1 gb:NM_002933.1 gb:D26129.1" NM_002933 "ribonuclease, RNase A family, 1 (pancreatic)" RNASE1 6035 NM_002933 /// NM_198232 /// NM_198234 /// NM_198235 "0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement" 0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016892 // endoribonuclease activity, producing 3'-phosphomonoesters // inferred from electronic annotation" 201786_s_at NM_001111 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001111.2 /DEF=Homo sapiens adenosine deaminase, RNA-specific (ADAR), transcript variant ADAR-a, mRNA. /FEA=mRNA /GEN=ADAR /PROD=adenosine deaminase, RNA-specific, isoformADAR-a /DB_XREF=gi:7669471 /UG=Hs.7957 adenosine deaminase, RNA-specific /FL=gb:U10439.1 gb:NM_001111.2 gb:U18121.1" NM_001111 "adenosine deaminase, RNA-specific" ADAR 103 NM_001025107 /// NM_001111 /// NM_001193495 /// NM_015840 /// NM_015841 /// XM_006711109 /// XM_006711110 /// XM_006711111 /// XM_006711112 /// XM_006711113 0002376 // immune system process // inferred from electronic annotation /// 0006382 // adenosine to inosine editing // inferred from direct assay /// 0006382 // adenosine to inosine editing // inferred from mutant phenotype /// 0006382 // adenosine to inosine editing // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from direct assay /// 0006611 // protein export from nucleus // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016553 // base conversion or substitution editing // inferred from direct assay /// 0016556 // mRNA modification // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from mutant phenotype /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0044530 // supraspliceosomal complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from direct assay /// 0003726 // double-stranded RNA adenosine deaminase activity // non-traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201787_at NM_001996 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001996.1 /DEF=Homo sapiens fibulin 1 (FBLN1), transcript variant C, mRNA. /FEA=mRNA /GEN=FBLN1 /PROD=fibulin 1 isoform C precursor /DB_XREF=gi:4503662 /UG=Hs.79732 fibulin 1 /FL=gb:NM_001996.1" NM_001996 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 201788_at NM_007372 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007372.1 /DEF=Homo sapiens RNA helicase-related protein (RNAHP), mRNA. /FEA=mRNA /GEN=RNAHP /PROD=RNA helicase-related protein /DB_XREF=gi:11321631 /UG=Hs.8765 RNA helicase-related protein /FL=gb:NM_007372.1 gb:AF083255.1" NM_007372 DEAD (Asp-Glu-Ala-Asp) box helicase 42 DDX42 11325 NM_007372 /// NM_203499 /// XM_006721657 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008104 // protein localization // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201789_at BC000637 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BC000637.1 /DEF=Homo sapiens, CGI-86 protein, clone MGC:681, mRNA, complete cds. /FEA=mRNA /PROD=CGI-86 protein /DB_XREF=gi:12653704 /UG=Hs.109201 CGI-86 protein /FL=gb:BC000637.1 gb:AF151844.1 gb:NM_016029.1" BC000637 pecanex-like 4 (Drosophila) PCNXL4 64430 NM_022495 /// XM_005268009 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201790_s_at AW150953 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW150953 /FEA=EST /DB_XREF=gi:6198851 /DB_XREF=est:xg42f09.x1 /CLONE=IMAGE:2630249 /UG=Hs.11806 7-dehydrocholesterol reductase /FL=gb:BC000054.1 gb:AF034544.1 gb:AF067127.1 gb:AF096305.1 gb:NM_001360.1 AW150953 7-dehydrocholesterol reductase DHCR7 1717 NM_001163817 /// NM_001360 0001568 // blood vessel development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045540 // regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005640 // nuclear outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from direct assay" 201791_s_at NM_001360 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001360.1 /DEF=Homo sapiens 7-dehydrocholesterol reductase (DHCR7), mRNA. /FEA=mRNA /GEN=DHCR7 /PROD=7-dehydrocholesterol reductase /DB_XREF=gi:4503320 /UG=Hs.11806 7-dehydrocholesterol reductase /FL=gb:BC000054.1 gb:AF034544.1 gb:AF067127.1 gb:AF096305.1 gb:NM_001360.1" NM_001360 7-dehydrocholesterol reductase DHCR7 1717 NM_001163817 /// NM_001360 0001568 // blood vessel development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045540 // regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005640 // nuclear outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from direct assay" 201792_at NM_001129 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001129.2 /DEF=Homo sapiens AE-binding protein 1 (AEBP1), mRNA. /FEA=mRNA /GEN=AEBP1 /PROD=adipocyte enhancer binding protein 1 precursor /DB_XREF=gi:4755145 /UG=Hs.118397 AE-binding protein 1 /FL=gb:D86479.1 gb:AF053944.1 gb:NM_001129.2" NM_001129 AE binding protein 1 AEBP1 165 NM_001129 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007517 // muscle organ development // traceable author statement" 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 201793_x_at BF509099 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF509099 /FEA=EST /DB_XREF=gi:11592397 /DB_XREF=est:UI-H-BI4-aou-e-05-0-UI.s1 /CLONE=IMAGE:3086288 /UG=Hs.15087 KIAA0250 gene product /FL=gb:D87437.1 gb:NM_014837.1 BF509099 SMG7 nonsense mediated mRNA decay factor SMG7 9887 NM_001174061 /// NM_014837 /// NM_173156 /// NM_201568 /// NM_201569 /// XM_005245647 /// XM_005245648 /// XM_005245649 /// XM_005245652 /// XM_005245653 /// XM_005245654 /// XM_005245655 /// XM_005245656 /// XM_006711674 /// XM_006711675 /// XM_006711676 /// XM_006711677 /// XM_006711678 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 201794_s_at NM_014837 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014837.1 /DEF=Homo sapiens KIAA0250 gene product (KIAA0250), mRNA. /FEA=mRNA /GEN=KIAA0250 /PROD=KIAA0250 gene product /DB_XREF=gi:7662023 /UG=Hs.15087 KIAA0250 gene product /FL=gb:D87437.1 gb:NM_014837.1" NM_014837 SMG7 nonsense mediated mRNA decay factor SMG7 9887 NM_001174061 /// NM_014837 /// NM_173156 /// NM_201568 /// NM_201569 /// XM_005245647 /// XM_005245648 /// XM_005245649 /// XM_005245652 /// XM_005245653 /// XM_005245654 /// XM_005245655 /// XM_005245656 /// XM_006711674 /// XM_006711675 /// XM_006711676 /// XM_006711677 /// XM_006711678 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 201795_at NM_002296 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002296.1 /DEF=Homo sapiens lamin B receptor (LBR), mRNA. /FEA=mRNA /GEN=LBR /PROD=lamin B receptor /DB_XREF=gi:4504960 /UG=Hs.152931 lamin B receptor /FL=gb:L25931.1 gb:NM_002296.1" NM_002296 lamin B receptor LBR 3930 NM_002296 /// NM_194442 /// XM_005273125 0006695 // cholesterol biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005639 // integral component of nuclear inner membrane // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // traceable author statement /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070087 // chromo shadow domain binding // inferred from physical interaction" 201796_s_at BE790854 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE790854 /FEA=EST /DB_XREF=gi:10212052 /DB_XREF=est:601582271F1 /CLONE=IMAGE:3936952 /UG=Hs.159637 valyl-tRNA synthetase 2 /FL=gb:NM_006295.1 BE790854 valyl-tRNA synthetase VARS 7407 NM_006295 /// XM_005249362 /// XM_005272869 /// XM_005274886 /// XM_005275021 /// XM_005275290 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201797_s_at NM_006295 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006295.1 /DEF=Homo sapiens valyl-tRNA synthetase 2 (VARS2), mRNA. /FEA=mRNA /GEN=VARS2 /PROD=valyl-tRNA synthetase 2 /DB_XREF=gi:5454157 /UG=Hs.159637 valyl-tRNA synthetase 2 /FL=gb:NM_006295.1" NM_006295 valyl-tRNA synthetase VARS 7407 NM_006295 /// XM_005249362 /// XM_005272869 /// XM_005274886 /// XM_005275021 /// XM_005275290 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201798_s_at NM_013451 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013451.1 /DEF=Homo sapiens fer-1 (C.elegans)-like 3 (myoferlin) (FER1L3), mRNA. /FEA=mRNA /GEN=FER1L3 /PROD=fer-1 (C.elegans)-like 3 (myoferlin) /DB_XREF=gi:7305052 /UG=Hs.234680 fer-1 (C.elegans)-like 3 (myoferlin) /FL=gb:AF182316.1 gb:NM_013451.1" NM_013451 myoferlin MYOF 26509 NM_013451 /// NM_133337 /// XM_005269693 /// XM_005269694 /// XM_006717760 0001778 // plasma membrane repair // inferred from sequence or structural similarity /// 0006936 // muscle contraction // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0030947 // regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from sequence or structural similarity 201799_s_at AI927993 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI927993 /FEA=EST /DB_XREF=gi:5663957 /DB_XREF=est:wo92c11.x1 /CLONE=IMAGE:2462804 /UG=Hs.24734 oxysterol binding protein /FL=gb:AF185696.1 gb:M86917.1 gb:NM_002556.1 AI927993 oxysterol binding protein OSBP 5007 NM_002556 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008142 // oxysterol binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 201800_s_at AF185696 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF185696.1 /DEF=Homo sapiens oxysterol-binding protein 1 (OSBP1) mRNA, complete cds. /FEA=mRNA /GEN=OSBP1 /PROD=oxysterol-binding protein 1 /DB_XREF=gi:10441379 /UG=Hs.24734 oxysterol binding protein /FL=gb:AF185696.1 gb:M86917.1 gb:NM_002556.1" AF185696 oxysterol binding protein OSBP 5007 NM_002556 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008142 // oxysterol binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 201801_s_at AF079117 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF079117.1 /DEF=Homo sapiens equilibrative NBMPR-sensitive nucleoside transporter (ENT1) mRNA, complete cds. /FEA=mRNA /GEN=ENT1 /PROD=equilibrative NBMPR-sensitive nucleosidetransporter /DB_XREF=gi:3694939 /UG=Hs.25450 solute carrier family 29 (nucleoside transporters), member 1 /FL=gb:BC001382.1 gb:U81375.1 gb:AF079117.1 gb:NM_004955.1" AF079117 "solute carrier family 29 (equilibrative nucleoside transporter), member 1" SLC29A1 2030 NM_001078174 /// NM_001078175 /// NM_001078176 /// NM_001078177 /// NM_004955 /// XM_005248875 /// XM_005248876 /// XM_005248878 /// XM_005248879 /// XM_005248880 /// XM_005248881 /// XM_005248882 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0015858 // nucleoside transport // inferred from direct assay /// 0015862 // uridine transport // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation 201802_at NM_004955 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004955.1 /DEF=Homo sapiens solute carrier family 29 (nucleoside transporters), member 1 (SLC29A1), mRNA. /FEA=mRNA /GEN=SLC29A1 /PROD=solute carrier family 29 (nucleosidetransporters), member 1 /DB_XREF=gi:4826715 /UG=Hs.25450 solute carrier family 29 (nucleoside transporters), member 1 /FL=gb:BC001382.1 gb:U81375.1 gb:AF079117.1 gb:NM_004955.1" NM_004955 "solute carrier family 29 (equilibrative nucleoside transporter), member 1" SLC29A1 2030 NM_001078174 /// NM_001078175 /// NM_001078176 /// NM_001078177 /// NM_004955 /// XM_005248875 /// XM_005248876 /// XM_005248878 /// XM_005248879 /// XM_005248880 /// XM_005248881 /// XM_005248882 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0015858 // nucleoside transport // inferred from direct assay /// 0015862 // uridine transport // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // inferred from electronic annotation /// 1901642 // nucleoside transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation 201803_at NM_000938 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000938.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide B (140kD) (POLR2B), mRNA. /FEA=mRNA /GEN=POLR2B /PROD=polymerase (RNA) II (DNA directed) polypeptide B(140kD) /DB_XREF=gi:4505940 /UG=Hs.296014 polymerase (RNA) II (DNA directed) polypeptide B (140kD) /FL=gb:NM_000938.1" NM_000938 "polymerase (RNA) II (DNA directed) polypeptide B, 140kDa" POLR2B 5431 NM_000938 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" "0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay" 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0032549 // ribonucleoside binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201804_x_at NM_001281 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001281.1 /DEF=Homo sapiens cytoskeleton-associated protein 1 (CKAP1), mRNA. /FEA=mRNA /GEN=CKAP1 /PROD=CKAP1 /DB_XREF=gi:4502848 /UG=Hs.31053 cytoskeleton-associated protein 1 /FL=gb:AF013488.1 gb:NM_001281.1 gb:D49738.1" NM_001281 tubulin folding cofactor B TBCB 1155 NM_001281 /// XM_006722998 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // traceable author statement 0005515 // protein binding // inferred from physical interaction 201805_at NM_002733 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002733.1 /DEF=Homo sapiens protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), mRNA. /FEA=mRNA /GEN=PRKAG1 /PROD=protein kinase, AMP-activated, gamma 1non-catalytic subunit /DB_XREF=gi:4506060 /UG=Hs.3136 protein kinase, AMP-activated, gamma 1 non-catalytic subunit /FL=gb:BC000358.1 gb:U42412.1 gb:NM_002733.1" NM_002733 "protein kinase, AMP-activated, gamma 1 non-catalytic subunit" PRKAG1 5571 NM_001206709 /// NM_001206710 /// NM_002733 /// NM_212461 /// XM_005269019 /// XM_005269020 /// XM_006719499 /// XM_006719500 0006110 // regulation of glycolytic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031588 // AMP-activated protein kinase complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004679 // AMP-activated protein kinase activity // inferred from sequence or structural similarity /// 0004691 // cAMP-dependent protein kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008603 // cAMP-dependent protein kinase regulator activity // traceable author statement /// 0016208 // AMP binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from direct assay /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from sequence or structural similarity 201806_s_at NM_007245 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007245.1 /DEF=Homo sapiens ataxin 2 related protein (A2LP), transcript variant 1, mRNA. /FEA=mRNA /GEN=A2LP /PROD=ataxin 2 related protein, isoform 1 /DB_XREF=gi:6005698 /UG=Hs.43509 ataxin 2 related protein /FL=gb:AF034373.1 gb:NM_007245.1" NM_007245 ataxin 2-like ATXN2L 11273 NM_007245 /// NM_017492 /// NM_145714 /// NM_148414 /// NM_148415 /// NM_148416 /// XM_005255061 /// XM_005255062 /// XM_005255063 /// XM_005255064 /// XM_005255065 /// XM_005255066 /// XM_005255067 /// XM_005255068 /// XM_005255069 /// XM_005255070 /// XM_005255071 /// XM_005255072 /// XM_005255074 /// XM_005255075 /// XM_005255076 /// XM_005255077 /// XM_006721007 /// XM_006721008 /// XM_006721009 /// XM_006721010 /// XM_006721011 /// XM_006721012 /// XM_006721013 /// XR_243256 0010603 // regulation of cytoplasmic mRNA processing body assembly // inferred from direct assay /// 0034063 // stress granule assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201807_at NM_004896 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004896.1 /DEF=Homo sapiens vacuolar protein sorting 26 (yeast homolog) (VPS26), mRNA. /FEA=mRNA /GEN=VPS26 /PROD=vacuolar protein sorting 26 (yeast homolog) /DB_XREF=gi:4758509 /UG=Hs.67052 vacuolar protein sorting 26 (yeast homolog) /FL=gb:AF054179.1 gb:NM_004896.1 gb:AF175266.1" NM_004896 vacuolar protein sorting 26 homolog A (S. pombe) VPS26A 9559 NM_001035260 /// NM_004896 "0006810 // transport // inferred from electronic annotation /// 0007034 // vacuolar transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // non-traceable author statement" 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030904 // retromer complex // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // non-traceable author statement 201808_s_at BE732652 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE732652 /FEA=EST /DB_XREF=gi:10146644 /DB_XREF=est:601571266F1 /CLONE=IMAGE:3925601 /UG=Hs.76753 endoglin (Osler-Rendu-Weber syndrome 1) /FL=gb:NM_000118.1 BE732652 endoglin ENG 2022 NM_000118 /// NM_001114753 /// NM_001278138 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001300 // chronological cell aging // inferred from electronic annotation /// 0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from mutant phenotype /// 0003273 // cell migration involved in endocardial cushion formation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0022009 // central nervous system vasculogenesis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0030155 // regulation of cell adhesion // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036273 // response to statin // inferred from electronic annotation /// 0042060 // wound healing // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042325 // regulation of phosphorylation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048845 // venous blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from mutant phenotype /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0070278 // extracellular matrix constituent secretion // inferred from electronic annotation /// 0070483 // detection of hypoxia // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation" 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator /// 0072563 // endothelial microparticle // inferred from electronic annotation "0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005072 // transforming growth factor beta receptor, cytoplasmic mediator activity // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005534 // galactose binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0048185 // activin binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from physical interaction" 201809_s_at NM_000118 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000118.1 /DEF=Homo sapiens endoglin (Osler-Rendu-Weber syndrome 1) (ENG), mRNA. /FEA=mRNA /GEN=ENG /PROD=endoglin precursor /DB_XREF=gi:4557554 /UG=Hs.76753 endoglin (Osler-Rendu-Weber syndrome 1) /FL=gb:NM_000118.1" NM_000118 endoglin ENG 2022 NM_000118 /// NM_001114753 /// NM_001278138 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001300 // chronological cell aging // inferred from electronic annotation /// 0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from mutant phenotype /// 0003273 // cell migration involved in endocardial cushion formation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0022009 // central nervous system vasculogenesis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0030155 // regulation of cell adhesion // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036273 // response to statin // inferred from electronic annotation /// 0042060 // wound healing // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042325 // regulation of phosphorylation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048845 // venous blood vessel morphogenesis // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from mutant phenotype /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060348 // bone development // inferred from electronic annotation /// 0060394 // negative regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0070278 // extracellular matrix constituent secretion // inferred from electronic annotation /// 0070483 // detection of hypoxia // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from electronic annotation" 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator /// 0072563 // endothelial microparticle // inferred from electronic annotation "0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005072 // transforming growth factor beta receptor, cytoplasmic mediator activity // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005534 // galactose binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0048185 // activin binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from physical interaction" 201810_s_at AL562152 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL562152 /FEA=EST /DB_XREF=gi:12910291 /DB_XREF=est:AL562152 /CLONE=CS0DC001YK23 (3 prime) /UG=Hs.109150 SH3-domain binding protein 5 (BTK-associated) /FL=gb:AB005047.1 gb:NM_004844.1 AL562152 SH3-domain binding protein 5 (BTK-associated) SH3BP5 9467 NM_001018009 /// NM_004844 /// XM_006713420 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 201811_x_at NM_004844 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004844.1 /DEF=Homo sapiens SH3-domain binding protein 5 (BTK-associated) (SH3BP5), mRNA. /FEA=mRNA /GEN=SH3BP5 /PROD=SH3-domain binding protein 5 (BTK-associated) /DB_XREF=gi:4759057 /UG=Hs.109150 SH3-domain binding protein 5 (BTK-associated) /FL=gb:AB005047.1 gb:NM_004844.1" NM_004844 SH3-domain binding protein 5 (BTK-associated) SH3BP5 9467 NM_001018009 /// NM_004844 /// XM_006713420 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 201812_s_at NM_019059 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019059.1 /DEF=Homo sapiens 6.2 kd protein (LOC54543), mRNA. /FEA=mRNA /GEN=LOC54543 /PROD=6.2 kd protein /DB_XREF=gi:9506858 /UG=Hs.112318 6.2 kd protein /FL=gb:BC001732.1 gb:AF150733.1 gb:NM_019059.1" NM_019059 chromosome 4 open reading frame 46 /// translocase of outer mitochondrial membrane 7 homolog (yeast) C4orf46 /// TOMM7 54543 /// 201725 NM_001008393 /// NM_019059 /// NR_077234 /// NR_077235 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030150 // protein import into mitochondrial matrix // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201813_s_at AI654161 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI654161 /FEA=EST /DB_XREF=gi:4738140 /DB_XREF=est:ty62e04.x1 /CLONE=IMAGE:2283678 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 AI654161 "TBC1 domain family, member 5" TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_005265611 /// XM_005265612 /// XM_005265613 /// XM_005265614 /// XM_005265615 /// XM_005265616 /// XM_006713429 /// XM_006713430 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0030904 // retromer complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201814_at AI300084 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI300084 /FEA=EST /DB_XREF=gi:3959430 /DB_XREF=est:qn59f02.x1 /CLONE=IMAGE:1902555 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 AI300084 "TBC1 domain family, member 5" TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_005265611 /// XM_005265612 /// XM_005265613 /// XM_005265614 /// XM_005265615 /// XM_005265616 /// XM_006713429 /// XM_006713430 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0030904 // retromer complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201815_s_at NM_014744 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014744.1 /DEF=Homo sapiens KIAA0210 gene product (KIAA0210), mRNA. /FEA=mRNA /GEN=KIAA0210 /PROD=KIAA0210 gene product /DB_XREF=gi:7661997 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1" NM_014744 "TBC1 domain family, member 5" TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_005265611 /// XM_005265612 /// XM_005265613 /// XM_005265614 /// XM_005265615 /// XM_005265616 /// XM_006713429 /// XM_006713430 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0030904 // retromer complex // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201816_s_at NM_001483 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001483.1 /DEF=Homo sapiens glioblastoma amplified sequence (GBAS), mRNA. /FEA=mRNA /GEN=GBAS /PROD=glioblastoma amplified sequence /DB_XREF=gi:4503936 /UG=Hs.152707 glioblastoma amplified sequence /FL=gb:BC000732.1 gb:BC001837.1 gb:AF029786.1 gb:NM_001483.1" NM_001483 glioblastoma amplified sequence GBAS 2631 NM_001202469 /// NM_001483 0006119 // oxidative phosphorylation // inferred from mutant phenotype /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 2000984 // negative regulation of ATP citrate synthase activity // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 201817_at NM_014671 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014671.1 /DEF=Homo sapiens KIAA0010 gene product (KIAA0010), mRNA. /FEA=mRNA /GEN=KIAA0010 /PROD=KIAA0010 gene product /DB_XREF=gi:7661855 /UG=Hs.155287 KIAA0010 gene product /FL=gb:D13635.1 gb:NM_014671.1" NM_014671 ubiquitin protein ligase E3C UBE3C 9690 NM_014671 /// XM_005249564 /// XM_005249565 0000209 // protein polyubiquitination // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded 0000502 // proteasome complex // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 201818_at NM_024830 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024830.1 /DEF=Homo sapiens hypothetical protein FLJ12443 (FLJ12443), mRNA. /FEA=mRNA /GEN=FLJ12443 /PROD=hypothetical protein FLJ12443 /DB_XREF=gi:13376233 /UG=Hs.179882 hypothetical protein FLJ12443 /FL=gb:NM_024830.1" NM_024830 lysophosphatidylcholine acyltransferase 1 LPCAT1 79888 NM_024830 /// XM_005248373 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from sequence or structural similarity /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // inferred from direct assay /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 2001246 // negative regulation of phosphatidylcholine biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0005509 // calcium ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047159 // 1-alkenylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from direct assay /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from sequence or structural similarity /// 0047191 // 1-alkylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation /// 0047192 // 1-alkylglycerophosphocholine O-acetyltransferase activity // inferred from electronic annotation" 201819_at NM_005505 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005505.1 /DEF=Homo sapiens CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 (CD36L1), mRNA. /FEA=mRNA /GEN=CD36L1 /PROD=CD36 antigen (collagen type I receptor,thrombospondin receptor)-like 1 /DB_XREF=gi:5031628 /UG=Hs.180616 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 /FL=gb:NM_005505.1" NM_005505 "scavenger receptor class B, member 1" SCARB1 949 NM_001082959 /// NM_005505 "0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from electronic annotation /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006910 // phagocytosis, recognition // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010886 // positive regulation of cholesterol storage // inferred from direct assay /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0015920 // lipopolysaccharide transport // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032497 // detection of lipopolysaccharide // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from sequence or structural similarity /// 0034375 // high-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0034383 // low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0042060 // wound healing // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043654 // recognition of apoptotic cell // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0044406 // adhesion of symbiont to host // inferred from mutant phenotype /// 0050764 // regulation of phagocytosis // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 0070508 // cholesterol import // inferred from sequence or structural similarity" 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0001786 // phosphatidylserine binding // inferred from sequence or structural similarity /// 0001875 // lipopolysaccharide receptor activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0008035 // high-density lipoprotein particle binding // inferred from electronic annotation /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0070506 // high-density lipoprotein particle receptor activity // inferred from direct assay 201820_at NM_000424 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000424.1 /DEF=Homo sapiens keratin 5 (epidermolysis bullosa simplex, Dowling-MearaKobnerWeber-Cockayne types) (KRT5), mRNA. /FEA=mRNA /GEN=KRT5 /PROD=keratin 5 (epidermolysis bullosa simplex,Dowling-MearaKobnerWeber-Cockayne types) /DB_XREF=gi:4557889 /UG=Hs.195850 keratin 5 (epidermolysis bullosa simplex, Dowling-MearaKobnerWeber-Cockayne types) /FL=gb:M21389.1 gb:NM_000424.1" NM_000424 keratin 5 KRT5 3852 NM_000424 0008544 // epidermis development // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0097110 // scaffold protein binding // inferred from physical interaction 201821_s_at BC004439 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC004439.1 /DEF=Homo sapiens, translocase of inner mitochondrial membrane 17 (yeast) homolog A, clone MGC:4031, mRNA, complete cds. /FEA=mRNA /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog A /DB_XREF=gi:13325239 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A /FL=gb:BC004439.1 gb:AF106622.1 gb:NM_006335.1" BC004439 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 201822_at NM_006335 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006335.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 17 (yeast) homolog A (TIM17), mRNA. /FEA=mRNA /GEN=TIM17 /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog A /DB_XREF=gi:5454119 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A /FL=gb:BC004439.1 gb:AF106622.1 gb:NM_006335.1" NM_006335 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 201823_s_at NM_004290 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004290.1 /DEF=Homo sapiens ring finger protein 14 (RNF14), mRNA. /FEA=mRNA /GEN=RNF14 /PROD=ring finger protein 14 /DB_XREF=gi:4757761 /UG=Hs.215857 ring finger protein 14 /FL=gb:AF060544.1 gb:NM_004290.1 gb:AB022663.1" NM_004290 ring finger protein 14 RNF14 9604 NM_001201365 /// NM_004290 /// NM_183398 /// NM_183399 /// NM_183400 /// NM_183401 /// XM_005268536 /// XM_005268537 /// XM_005268538 /// XM_005268539 /// XM_005268540 /// XM_005268541 /// XM_005268542 /// XM_005268543 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from expression pattern /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // non-traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 201824_at AB022663 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB022663.1 /DEF=Homo sapiens HFB30 mRNA, complete cds. /FEA=mRNA /GEN=HFB30 /DB_XREF=gi:5019617 /UG=Hs.215857 ring finger protein 14 /FL=gb:AF060544.1 gb:NM_004290.1 gb:AB022663.1" AB022663 ring finger protein 14 RNF14 9604 NM_001201365 /// NM_004290 /// NM_183398 /// NM_183399 /// NM_183400 /// NM_183401 /// XM_005268536 /// XM_005268537 /// XM_005268538 /// XM_005268539 /// XM_005268540 /// XM_005268541 /// XM_005268542 /// XM_005268543 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from expression pattern /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // non-traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 201825_s_at AL572542 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL572542 /FEA=EST /DB_XREF=gi:12930912 /DB_XREF=est:AL572542 /CLONE=CS0DI008YC09 (3 prime) /UG=Hs.238126 CGI-49 protein /FL=gb:AF151807.1 gb:NM_016002.1 AL572542 saccharopine dehydrogenase (putative) SCCPDH 51097 NM_016002 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation 201826_s_at NM_016002 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016002.1 /DEF=Homo sapiens CGI-49 protein (LOC51097), mRNA. /FEA=mRNA /GEN=LOC51097 /PROD=CGI-49 protein /DB_XREF=gi:7705766 /UG=Hs.238126 CGI-49 protein /FL=gb:AF151807.1 gb:NM_016002.1" NM_016002 saccharopine dehydrogenase (putative) SCCPDH 51097 NM_016002 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation 201827_at AF113019 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF113019.1 /DEF=Homo sapiens PRO2451 mRNA, complete cds. /FEA=mRNA /PROD=PRO2451 /DB_XREF=gi:6642761 /UG=Hs.250581 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 /FL=gb:U66618.1 gb:NM_003077.1 gb:AF113019.1" AF113019 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2" SMARCD2 6603 NM_001098426 /// NM_003077 /// XM_005257604 "0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 201828_x_at NM_003928 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003928.1 /DEF=Homo sapiens CAAX box 1 (CXX1), mRNA. /FEA=mRNA /GEN=CXX1 /PROD=CAAX box 1 /DB_XREF=gi:4503180 /UG=Hs.250708 CAAX box 1 /FL=gb:BC002385.1 gb:BC002410.1 gb:AF038168.1 gb:AF052096.1 gb:NM_003928.1" NM_003928 "family with sequence similarity 127, member A" FAM127A 8933 NM_001078171 /// NM_003928 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201829_at AW263232 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW263232 /FEA=EST /DB_XREF=gi:6640048 /DB_XREF=est:xn79e03.x1 /CLONE=IMAGE:2700700 /UG=Hs.25155 neuroepithelial cell transforming gene 1 /FL=gb:NM_005863.1 gb:U02081.1 AW263232 neuroepithelial cell transforming 1 NET1 10276 NM_001047160 /// NM_005863 /// NR_073040 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 201830_s_at NM_005863 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005863.1 /DEF=Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA. /FEA=mRNA /GEN=NET1 /PROD=neuroepithelial cell transforming gene 1 /DB_XREF=gi:5031938 /UG=Hs.25155 neuroepithelial cell transforming gene 1 /FL=gb:NM_005863.1 gb:U02081.1" NM_005863 neuroepithelial cell transforming 1 NET1 10276 NM_001047160 /// NM_005863 /// NR_073040 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 201831_s_at BE875592 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE875592 /FEA=EST /DB_XREF=gi:10324368 /DB_XREF=est:601487031F1 /CLONE=IMAGE:3889710 /UG=Hs.325948 vesicle docking protein p115 /FL=gb:D86326.1 gb:NM_003715.1 BE875592 USO1 vesicle transport factor USO1 8615 NM_001290049 /// NM_003715 /// XM_006714395 /// XM_006714396 /// XM_006714397 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045056 // transcytosis // not recorded /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0048211 // Golgi vesicle docking // not recorded /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation /// 0061025 // membrane fusion // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0008565 // protein transporter activity // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay 201832_s_at NM_003715 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003715.1 /DEF=Homo sapiens vesicle docking protein p115 (P115), mRNA. /FEA=mRNA /GEN=P115 /PROD=vesicle docking protein p115 /DB_XREF=gi:4505540 /UG=Hs.325948 vesicle docking protein p115 /FL=gb:D86326.1 gb:NM_003715.1" NM_003715 USO1 vesicle transport factor USO1 8615 NM_001290049 /// NM_003715 /// XM_006714395 /// XM_006714396 /// XM_006714397 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045056 // transcytosis // not recorded /// 0048193 // Golgi vesicle transport // inferred from electronic annotation /// 0048211 // Golgi vesicle docking // not recorded /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation /// 0061025 // membrane fusion // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0008565 // protein transporter activity // not recorded /// 0044822 // poly(A) RNA binding // inferred from direct assay 201833_at NM_001527 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001527.1 /DEF=Homo sapiens histone deacetylase 2 (HDAC2), mRNA. /FEA=mRNA /GEN=HDAC2 /PROD=histone deacetylase 2 /DB_XREF=gi:4557640 /UG=Hs.3352 histone deacetylase 2 /FL=gb:U31814.1 gb:NM_001527.1" NM_001527 histone deacetylase 2 HDAC2 3066 NM_001527 /// NR_033441 /// NR_073443 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred by curator /// 0006344 // maintenance of chromatin silencing // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006476 // protein deacetylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009913 // epidermal cell differentiation // inferred from sequence or structural similarity /// 0010870 // positive regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0032967 // positive regulation of collagen biosynthetic process // inferred by curator /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred by curator /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred by curator /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0055013 // cardiac muscle cell development // inferred from electronic annotation /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060297 // regulation of sarcomere organization // inferred from electronic annotation /// 0060789 // hair follicle placode formation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0061198 // fungiform papilla formation // inferred from sequence or structural similarity /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity /// 0070933 // histone H4 deacetylation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090311 // regulation of protein deacetylation // inferred from electronic annotation /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation" 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0016580 // Sin3 complex // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from electronic annotation /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001047 // core promoter binding // inferred from electronic annotation /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from mutant phenotype /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 201834_at BC001007 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001007.1 /DEF=Homo sapiens, protein kinase, AMP-activated, beta 1 non-catalytic subunit, clone MGC:8608, mRNA, complete cds. /FEA=mRNA /PROD=protein kinase, AMP-activated, beta 1non-catalytic subunit /DB_XREF=gi:12654368 /UG=Hs.6061 protein kinase, AMP-activated, beta 1 non-catalytic subunit /FL=gb:BC001007.1 gb:BC001056.1 gb:BC001823.1 gb:AF022116.1 gb:U83994.1 gb:NM_006253.1" BC001007 "protein kinase, AMP-activated, beta 1 non-catalytic subunit" PRKAB1 5564 NM_006253 /// XM_005253909 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 201835_s_at NM_006253 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006253.1 /DEF=Homo sapiens protein kinase, AMP-activated, beta 1 non-catalytic subunit (PRKAB1), mRNA. /FEA=mRNA /GEN=PRKAB1 /PROD=protein kinase, AMP-activated, beta 1non-catalytic subunit /DB_XREF=gi:5453967 /UG=Hs.6061 protein kinase, AMP-activated, beta 1 non-catalytic subunit /FL=gb:BC001007.1 gb:BC001056.1 gb:BC001823.1 gb:AF022116.1 gb:U83994.1 gb:NM_006253.1" NM_006253 "protein kinase, AMP-activated, beta 1 non-catalytic subunit" PRKAB1 5564 NM_006253 /// XM_005253909 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031588 // AMP-activated protein kinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 201836_s_at AU154740 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU154740 /FEA=EST /DB_XREF=gi:11016261 /DB_XREF=est:AU154740 /CLONE=NT2RP4001989 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1 AU154740 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_001282729 /// NM_001282730 /// NM_001282731 /// NM_001282732 /// NM_014860 /// XM_005264672 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201837_s_at AF197954 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF197954.1 /DEF=Homo sapiens adenocarcinoma antigen ART1 mRNA, complete cds. /FEA=mRNA /PROD=adenocarcinoma antigen ART1 /DB_XREF=gi:11066257 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1" AF197954 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_001282729 /// NM_001282730 /// NM_001282731 /// NM_001282732 /// NM_014860 /// XM_005264672 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201838_s_at NM_014860 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014860.1 /DEF=Homo sapiens KIAA0764 gene product (KIAA0764), mRNA. /FEA=mRNA /GEN=KIAA0764 /PROD=KIAA0764 gene product /DB_XREF=gi:7662291 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1" NM_014860 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_001282729 /// NM_001282730 /// NM_001282731 /// NM_001282732 /// NM_014860 /// XM_005264672 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201839_s_at NM_002354 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002354.1 /DEF=Homo sapiens tumor-associated calcium signal transducer 1 (TACSTD1), mRNA. /FEA=mRNA /GEN=TACSTD1 /PROD=tumor-associated calcium signal transducer 1precursor /DB_XREF=gi:4505058 /UG=Hs.692 tumor-associated calcium signal transducer 1 /FL=gb:M32306.1 gb:M33011.1 gb:NM_002354.1" NM_002354 epithelial cell adhesion molecule EPCAM 4072 NM_002354 0001657 // ureteric bud development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0023019 // signal transduction involved in regulation of gene expression // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048863 // stem cell differentiation // inferred from mutant phenotype /// 2000048 // negative regulation of cell-cell adhesion mediated by cadherin // inferred from direct assay /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay 201840_at NM_006156 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006156.1 /DEF=Homo sapiens neural precursor cell expressed, developmentally down-regulated 8 (NEDD8), mRNA. /FEA=mRNA /GEN=NEDD8 /PROD=neural precursor cell expressed, developmentallydown-regulated 8 /DB_XREF=gi:5453759 /UG=Hs.75512 neural precursor cell expressed, developmentally down-regulated 8 /FL=gb:D23662.1 gb:NM_006156.1" NM_006156 "neural precursor cell expressed, developmentally down-regulated 8" NEDD8 4738 NM_006156 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0045116 // protein neddylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201841_s_at NM_001540 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001540.2 /DEF=Homo sapiens heat shock 27kD protein 1 (HSPB1), mRNA. /FEA=mRNA /GEN=HSPB1 /PROD=heat shock 27kD protein 1 /DB_XREF=gi:4996892 /UG=Hs.76067 heat shock 27kD protein 1 /FL=gb:AB020027.1 gb:BC000510.1 gb:U90906.1 gb:NM_001540.2" NM_001540 heat shock 27kDa protein 1 HSPB1 3315 NM_001540 0001895 // retina homeostasis // inferred from expression pattern /// 0006446 // regulation of translational initiation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0006928 // cellular component movement // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0032731 // positive regulation of interleukin-1 beta production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038033 // positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043122 // regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000502 // proteasome complex // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008426 // protein kinase C inhibitor activity // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 201842_s_at AI826799 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI826799 /FEA=EST /DB_XREF=gi:5447470 /DB_XREF=est:wk56d07.x1 /CLONE=IMAGE:2419405 /UG=Hs.76224 EGF-containing fibulin-like extracellular matrix protein 1 /FL=gb:U03877.1 gb:NM_004105.2 AI826799 EGF containing fibulin-like extracellular matrix protein 1 EFEMP1 2202 NM_001039348 /// NM_001039349 /// NM_004105 /// XM_005264205 "0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 201843_s_at NM_004105 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004105.2 /DEF=Homo sapiens EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), transcript variant 1, mRNA. /FEA=mRNA /GEN=EFEMP1 /PROD=EGF-containing fibulin-like extracellular matrixprotein 1 precursor, isoform a precursor /DB_XREF=gi:9665261 /UG=Hs.76224 EGF-containing fibulin-like extracellular matrix protein 1 /FL=gb:U03877.1 gb:NM_004105.2" NM_004105 EGF containing fibulin-like extracellular matrix protein 1 EFEMP1 2202 NM_001039348 /// NM_001039349 /// NM_004105 /// XM_005264205 "0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation 201844_s_at W84482 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:W84482 /FEA=EST /DB_XREF=gi:1395613 /DB_XREF=est:zd89h07.s1 /CLONE=IMAGE:356701 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1 W84482 RING1 and YY1 binding protein RYBP 23429 NM_012234 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0035518 // histone H2A monoubiquitination // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201845_s_at AB029551 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB029551.1 /DEF=Homo sapiens YEAF1 mRNA for YY1 and E4TF1 associated factor 1, complete cds. /FEA=mRNA /GEN=YEAF1 /PROD=YY1 and E4TF1 associated factor 1 /DB_XREF=gi:6714542 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1" AB029551 RING1 and YY1 binding protein RYBP 23429 NM_012234 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0035518 // histone H2A monoubiquitination // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201846_s_at NM_012234 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012234.1 /DEF=Homo sapiens RING1 and YY1 binding protein (RYBP), mRNA. /FEA=mRNA /GEN=RYBP /PROD=RING1 and YY1 binding protein /DB_XREF=gi:6912639 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1" NM_012234 RING1 and YY1 binding protein RYBP 23429 NM_012234 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0035518 // histone H2A monoubiquitination // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201847_at NM_000235 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000235.1 /DEF=Homo sapiens lipase A, lysosomal acid, cholesterol esterase (Wolman disease) (LIPA), mRNA. /FEA=mRNA /GEN=LIPA /PROD=lipase A precursor /DB_XREF=gi:4557720 /UG=Hs.85226 lipase A, lysosomal acid, cholesterol esterase (Wolman disease) /FL=gb:M74775.1 gb:NM_000235.1 gb:U08464.1" NM_000235 "lipase A, lysosomal acid, cholesterol esterase" LIPA 3988 NM_000235 /// NM_001127605 /// NM_001288979 /// NR_110233 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004771 // sterol esterase activity // inferred from direct assay /// 0016298 // lipase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation" 201848_s_at U15174 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U15174.1 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 3 (BNIP3) mRNA, complete cds. /FEA=mRNA /GEN=BNIP3 /PROD=BCL2adenovirus E1B 19kD-interacting protein 3 /DB_XREF=gi:558845 /UG=Hs.79428 BCL2adenovirus E1B 19kD-interacting protein 3 /FL=gb:AF002697.1 gb:U15174.1 gb:NM_004052.2" U15174 BCL2/adenovirus E1B 19kDa interacting protein 3 BNIP3 664 NM_004052 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006915 // apoptotic process // inferred from physical interaction /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0010508 // positive regulation of autophagy // traceable author statement /// 0010637 // negative regulation of mitochondrial fusion // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035694 // mitochondrial protein catabolic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043068 // positive regulation of programmed cell death // inferred from direct assay /// 0043243 // positive regulation of protein complex disassembly // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 0045837 // negative regulation of membrane potential // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from direct assay /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071279 // cellular response to cobalt ion // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097345 // mitochondrial outer membrane permeabilization // inferred from direct assay /// 1990144 // intrinsic apoptotic signaling pathway in response to hypoxia // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 201849_at NM_004052 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004052.2 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=BNIP3 /PROD=BCL2adenovirus E1B 19kD-interacting protein 3 /DB_XREF=gi:7669480 /UG=Hs.79428 BCL2adenovirus E1B 19kD-interacting protein 3 /FL=gb:AF002697.1 gb:U15174.1 gb:NM_004052.2" NM_004052 BCL2/adenovirus E1B 19kDa interacting protein 3 BNIP3 664 NM_004052 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006915 // apoptotic process // inferred from physical interaction /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0010508 // positive regulation of autophagy // traceable author statement /// 0010637 // negative regulation of mitochondrial fusion // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035694 // mitochondrial protein catabolic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043068 // positive regulation of programmed cell death // inferred from direct assay /// 0043243 // positive regulation of protein complex disassembly // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from direct assay /// 0045837 // negative regulation of membrane potential // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048102 // autophagic cell death // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from direct assay /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071279 // cellular response to cobalt ion // inferred from mutant phenotype /// 0071456 // cellular response to hypoxia // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090141 // positive regulation of mitochondrial fission // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097345 // mitochondrial outer membrane permeabilization // inferred from direct assay /// 1990144 // intrinsic apoptotic signaling pathway in response to hypoxia // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051020 // GTPase binding // inferred from physical interaction 201850_at NM_001747 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001747.1 /DEF=Homo sapiens capping protein (actin filament), gelsolin-like (CAPG), mRNA. /FEA=mRNA /GEN=CAPG /PROD=capping protein (actin filament), gelsolin-like /DB_XREF=gi:4502560 /UG=Hs.82422 capping protein (actin filament), gelsolin-like /FL=gb:BC000728.1 gb:M94345.1 gb:NM_001747.1" NM_001747 "capping protein (actin filament), gelsolin-like" CAPG 822 NM_001256139 /// NM_001256140 /// NM_001747 /// XM_005264581 /// XM_005264582 0006461 // protein complex assembly // non-traceable author statement /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051693 // actin filament capping // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008290 // F-actin capping protein complex // traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 201851_at NM_003025 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003025.1 /DEF=Homo sapiens SH3-domain GRB2-like 1 (SH3GL1), mRNA. /FEA=mRNA /GEN=SH3GL1 /PROD=SH3-domain GRB2-like 1 /DB_XREF=gi:4506928 /UG=Hs.97616 SH3-domain GRB2-like 1 /FL=gb:BC001270.1 gb:U65999.1 gb:NM_003025.1" NM_003025 SH3-domain GRB2-like 1 SH3GL1 6455 NM_001199943 /// NM_001199944 /// NM_003025 0006897 // endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051020 // GTPase binding // inferred from electronic annotation 201852_x_at AI813758 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI813758 /FEA=EST /DB_XREF=gi:5424973 /DB_XREF=est:wk79b04.x1 /CLONE=IMAGE:2421583 /UG=Hs.119571 collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) /FL=gb:NM_000090.1" AI813758 "collagen, type III, alpha 1" COL3A1 1281 NM_000090 0001501 // skeletal system development // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from mutant phenotype /// 0007568 // aging // inferred from electronic annotation /// 0009314 // response to radiation // inferred from direct assay /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // non-traceable author statement /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 2001223 // negative regulation of neuron migration // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005586 // collagen type III trimer // inferred from mutant phenotype /// 0005586 // collagen type III trimer // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement 0005178 // integrin binding // inferred from mutant phenotype /// 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 201853_s_at NM_021873 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021873.1 /DEF=Homo sapiens cell division cycle 25B (CDC25B), transcript variant 3, mRNA. /FEA=mRNA /GEN=CDC25B /PROD=cell division cycle 25B, isoform 3 /DB_XREF=gi:11641412 /UG=Hs.153752 cell division cycle 25B /FL=gb:NM_021873.1" NM_021873 cell division cycle 25B CDC25B 994 NM_001287516 /// NM_001287517 /// NM_001287518 /// NM_001287519 /// NM_001287520 /// NM_001287522 /// NM_001287524 /// NM_004358 /// NM_021872 /// NM_021873 /// NM_021874 /// NM_212530 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000087 // mitotic M phase // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 201854_s_at AI744148 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI744148 /FEA=EST /DB_XREF=gi:5112436 /DB_XREF=est:wc36h01.x1 /CLONE=IMAGE:2317297 /UG=Hs.16349 KIAA0431 protein /FL=gb:NM_015251.1 AI744148 ATM interactor ATMIN 23300 NM_015251 /// XM_005255866 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201855_s_at NM_015251 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015251.1 /DEF=Homo sapiens KIAA0431 protein (KIAA0431), mRNA. /FEA=mRNA /GEN=KIAA0431 /PROD=KIAA0431 protein /DB_XREF=gi:7662115 /UG=Hs.16349 KIAA0431 protein /FL=gb:NM_015251.1" NM_015251 ATM interactor ATMIN 23300 NM_015251 /// XM_005255866 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0045502 // dynein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201856_s_at BC000376 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000376.1 /DEF=Homo sapiens, clone MGC:8379, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:8379) /DB_XREF=gi:12653216 /UG=Hs.173518 M-phase phosphoprotein homolog /FL=gb:BC000376.1 gb:BC000746.1 gb:AF100742.1 gb:NM_016107.1" BC000376 zinc finger RNA binding protein ZFR 51663 NM_016107 /// XM_006714477 /// XR_427659 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201857_at NM_016107 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016107.1 /DEF=Homo sapiens M-phase phosphoprotein homolog (LOC51663), mRNA. /FEA=mRNA /GEN=LOC51663 /PROD=M-phase phosphoprotein homolog /DB_XREF=gi:7706372 /UG=Hs.173518 M-phase phosphoprotein homolog /FL=gb:BC000376.1 gb:BC000746.1 gb:AF100742.1 gb:NM_016107.1" NM_016107 zinc finger RNA binding protein ZFR 51663 NM_016107 /// XM_006714477 /// XR_427659 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201858_s_at J03223 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J03223.1 /DEF=Human secretory granule proteoglycan peptide core mRNA, complete cds. /FEA=mRNA /GEN=PRG1 /DB_XREF=gi:190419 /UG=Hs.1908 proteoglycan 1, secretory granule /FL=gb:J03223.1 gb:NM_002727.1" J03223 serglycin SRGN 5552 NM_002727 /// NR_036430 0002576 // platelet degranulation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0033371 // T cell secretory granule organization // inferred from sequence or structural similarity /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from sequence or structural similarity /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0042588 // zymogen granule // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation 201859_at NM_002727 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002727.1 /DEF=Homo sapiens proteoglycan 1, secretory granule (PRG1), mRNA. /FEA=mRNA /GEN=PRG1 /PROD=proteoglycan 1, secretory granule /DB_XREF=gi:4506044 /UG=Hs.1908 proteoglycan 1, secretory granule /FL=gb:J03223.1 gb:NM_002727.1" NM_002727 serglycin SRGN 5552 NM_002727 /// NR_036430 0002576 // platelet degranulation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0016485 // protein processing // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0033371 // T cell secretory granule organization // inferred from sequence or structural similarity /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from sequence or structural similarity /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0042588 // zymogen granule // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation 201860_s_at NM_000930 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000930.1 /DEF=Homo sapiens plasminogen activator, tissue (PLAT), mRNA. /FEA=mRNA /GEN=PLAT /PROD=plasminogen activator, tissue /DB_XREF=gi:4505860 /UG=Hs.274404 plasminogen activator, tissue /FL=gb:NM_000931.1 gb:M15518.1 gb:M18182.1 gb:NM_000930.1" NM_000930 "plasminogen activator, tissue" PLAT 5327 NM_000930 /// NM_000931 /// NM_033011 "0001666 // response to hypoxia // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0014909 // smooth muscle cell migration // inferred from electronic annotation /// 0031639 // plasminogen activation // inferred from direct assay /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060279 // positive regulation of ovulation // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201861_s_at BF965566 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF965566 /FEA=EST /DB_XREF=gi:12332781 /DB_XREF=est:602277032F1 /CLONE=IMAGE:4364790 /UG=Hs.326159 leucine rich repeat (in FLII) interacting protein 1 /FL=gb:NM_004735.1 BF965566 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 /// XM_005246112 /// XM_005246113 /// XM_005246114 /// XM_005246115 /// XM_005246116 /// XM_005246117 /// XM_005246118 /// XM_005246119 /// XM_005246120 /// XM_005246121 /// XM_005246122 /// XM_005246123 /// XM_005246124 /// XM_005246125 /// XM_005246126 /// XM_005246127 /// XM_005246128 /// XM_005246129 /// XM_005246130 /// XM_005246131 /// XM_005246132 /// XM_005246133 /// XM_005246134 /// XM_005246135 /// XM_005246136 /// XM_005246137 /// XM_005246138 /// XM_005246139 /// XM_005246140 /// XM_005246141 /// XM_005246142 /// XM_006712840 /// XM_006712841 /// XM_006712842 /// XM_006712843 /// XM_006712844 /// XM_006712845 /// XM_006712846 /// XM_006712847 /// XM_006712848 /// XM_006712849 /// XM_006712850 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement" 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 201862_s_at NM_004735 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004735.1 /DEF=Homo sapiens leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), mRNA. /FEA=mRNA /GEN=LRRFIP1 /PROD=leucine rich repeat (in FLII) interactingprotein 1 /DB_XREF=gi:4758689 /UG=Hs.326159 leucine rich repeat (in FLII) interacting protein 1 /FL=gb:NM_004735.1" NM_004735 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 /// XM_005246112 /// XM_005246113 /// XM_005246114 /// XM_005246115 /// XM_005246116 /// XM_005246117 /// XM_005246118 /// XM_005246119 /// XM_005246120 /// XM_005246121 /// XM_005246122 /// XM_005246123 /// XM_005246124 /// XM_005246125 /// XM_005246126 /// XM_005246127 /// XM_005246128 /// XM_005246129 /// XM_005246130 /// XM_005246131 /// XM_005246132 /// XM_005246133 /// XM_005246134 /// XM_005246135 /// XM_005246136 /// XM_005246137 /// XM_005246138 /// XM_005246139 /// XM_005246140 /// XM_005246141 /// XM_005246142 /// XM_006712840 /// XM_006712841 /// XM_006712842 /// XM_006712843 /// XM_006712844 /// XM_006712845 /// XM_006712846 /// XM_006712847 /// XM_006712848 /// XM_006712849 /// XM_006712850 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement" 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 201863_at NM_014077 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014077.1 /DEF=Homo sapiens DKFZP586O0120 protein (DKFZP586O0120), mRNA. /FEA=mRNA /GEN=DKFZP586O0120 /PROD=DKFZP586O0120 protein /DB_XREF=gi:7661695 /UG=Hs.4766 DKFZP586O0120 protein /FL=gb:BC000639.1 gb:AL050157.1 gb:AF151902.1 gb:NM_014077.1" NM_014077 "family with sequence similarity 32, member A" FAM32A 26017 NM_014077 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201864_at NM_001493 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001493.1 /DEF=Homo sapiens GDP dissociation inhibitor 1 (GDI1), mRNA. /FEA=mRNA /GEN=GDI1 /PROD=GDP dissociation inhibitor 1 /DB_XREF=gi:4503970 /UG=Hs.74576 GDP dissociation inhibitor 1 /FL=gb:BC000317.1 gb:NM_001493.1 gb:D45021.1" NM_001493 GDP dissociation inhibitor 1 GDI1 2664 NM_001493 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0032482 // Rab protein signal transduction // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0090315 // negative regulation of protein targeting to membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030496 // midbody // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005093 // Rab GDP-dissociation inhibitor activity // inferred from sequence or structural similarity /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation 201865_x_at AI432196 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI432196 /FEA=EST /DB_XREF=gi:4308490 /DB_XREF=est:tg77g05.x1 /CLONE=IMAGE:2114840 /UG=Hs.75772 nuclear receptor subfamily 3, group C, member 1 /FL=gb:M10901.1 gb:NM_000176.1" AI432196 "nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)" NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 /// NM_001204258 /// NM_001204259 /// NM_001204260 /// NM_001204261 /// NM_001204262 /// NM_001204263 /// NM_001204264 /// NM_001204265 /// XM_005268419 /// XM_005268420 /// XM_005268421 /// XM_005268422 /// XM_005268423 "0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031946 // regulation of glucocorticoid biosynthetic process // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043402 // glucocorticoid mediated signaling pathway // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201866_s_at NM_000176 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000176.1 /DEF=Homo sapiens nuclear receptor subfamily 3, group C, member 1 (NR3C1), mRNA. /FEA=mRNA /GEN=NR3C1 /PROD=nuclear receptor subfamily 3, group C, member 1 /DB_XREF=gi:4504132 /UG=Hs.75772 nuclear receptor subfamily 3, group C, member 1 /FL=gb:M10901.1 gb:NM_000176.1" NM_000176 "nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)" NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 /// NM_001204258 /// NM_001204259 /// NM_001204260 /// NM_001204261 /// NM_001204262 /// NM_001204263 /// NM_001204264 /// NM_001204265 /// XM_005268419 /// XM_005268420 /// XM_005268421 /// XM_005268422 /// XM_005268423 "0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031946 // regulation of glucocorticoid biosynthetic process // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043402 // glucocorticoid mediated signaling pathway // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060603 // mammary gland duct morphogenesis // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201867_s_at AW968555 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW968555 /FEA=EST /DB_XREF=gi:8158396 /DB_XREF=est:EST380631 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 AW968555 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype" 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 201868_s_at AI082187 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI082187 /FEA=EST /DB_XREF=gi:3418979 /DB_XREF=est:ox75f01.x1 /CLONE=IMAGE:1662169 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 AI082187 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype" 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 201869_s_at BF593932 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF593932 /FEA=EST /DB_XREF=gi:11686256 /DB_XREF=est:nab48e09.x1 /CLONE=IMAGE:3269104 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 BF593932 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype" 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from genetic interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 201870_at NM_006809 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006809.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 34 (TOM34), mRNA. /FEA=mRNA /GEN=TOM34 /PROD=translocase of outer mitochondrial membrane 34 /DB_XREF=gi:5803204 /UG=Hs.76927 translocase of outer mitochondrial membrane 34 /FL=gb:BC001763.1 gb:U58970.1 gb:NM_006809.1" NM_006809 translocase of outer mitochondrial membrane 34 TOMM34 10953 NM_006809 /// XM_005260254 /// XR_244131 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from physical interaction 201871_s_at NM_015853 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015853.1 /DEF=Homo sapiens ORF (LOC51035), mRNA. /FEA=mRNA /GEN=LOC51035 /PROD=unknown protein LOC51035 /DB_XREF=gi:7705653 /UG=Hs.77868 ORF /FL=gb:BC000902.1 gb:M68864.1 gb:NM_015853.1" NM_015853 UBX domain protein 1 UBXN1 51035 NM_001286077 /// NM_001286078 /// NM_015853 /// XM_005274033 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // non-traceable author statement 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0034098 // Cdc48p-Npl4p-Ufd1p AAA ATPase complex // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction /// 0071796 // K6-linked polyubiquitin binding // inferred from direct assay 201872_s_at AI002002 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI002002 /FEA=EST /DB_XREF=gi:3202473 /DB_XREF=est:ot42e10.s1 /CLONE=IMAGE:1619466 /UG=Hs.12013 ATP-binding cassette, sub-family E (OABP), member 1 /FL=gb:NM_002940.1" AI002002 "ATP-binding cassette, sub-family E (OABP), member 1" ABCE1 6059 NM_001040876 /// NM_002940 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008428 // ribonuclease inhibitor activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 201873_s_at NM_002940 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002940.1 /DEF=Homo sapiens ATP-binding cassette, sub-family E (OABP), member 1 (ABCE1), mRNA. /FEA=mRNA /GEN=ABCE1 /PROD=ATP-binding cassette, sub-family E, member 1 /DB_XREF=gi:4506558 /UG=Hs.12013 ATP-binding cassette, sub-family E (OABP), member 1 /FL=gb:NM_002940.1" NM_002940 "ATP-binding cassette, sub-family E (OABP), member 1" ABCE1 6059 NM_001040876 /// NM_002940 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008428 // ribonuclease inhibitor activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 201874_at BF978611 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF978611 /FEA=EST /DB_XREF=gi:12345826 /DB_XREF=est:602149061F1 /CLONE=IMAGE:4307822 /UG=Hs.14891 hypothetical protein FLJ21047 /FL=gb:NM_024569.1 BF978611 myelin protein zero-like 1 MPZL1 9019 NM_001146191 /// NM_003953 /// NM_024569 /// XM_006711614 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201875_s_at NM_024569 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024569.1 /DEF=Homo sapiens hypothetical protein FLJ21047 (FLJ21047), mRNA. /FEA=mRNA /GEN=FLJ21047 /PROD=hypothetical protein FLJ21047 /DB_XREF=gi:13375739 /UG=Hs.14891 hypothetical protein FLJ21047 /FL=gb:NM_024569.1" NM_024569 myelin protein zero-like 1 MPZL1 9019 NM_001146191 /// NM_003953 /// NM_024569 /// XM_006711614 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201876_at NM_000305 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000305.1 /DEF=Homo sapiens paraoxonase 2 (PON2), mRNA. /FEA=mRNA /GEN=PON2 /PROD=paraoxonase 2 /DB_XREF=gi:4505952 /UG=Hs.169857 paraoxonase 2 /FL=gb:L48513.1 gb:AF001601.1 gb:NM_000305.1" NM_000305 paraoxonase 2 PON2 5445 NM_000305 /// NM_001018161 /// XM_005250453 /// XM_005250454 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from direct assay" 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004064 // arylesterase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201877_s_at NM_002719 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002719.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), gamma isoform (PPP2R5C), mRNA. /FEA=mRNA /GEN=PPP2R5C /PROD=protein phosphatase 2, regulatory subunit B(B56), gamma isoform /DB_XREF=gi:4506022 /UG=Hs.171734 protein phosphatase 2, regulatory subunit B (B56), gamma isoform /FL=gb:U37352.1 gb:NM_002719.1" NM_002719 "protein phosphatase 2, regulatory subunit B', gamma" PPP2R5C 5527 NM_001161725 /// NM_001161726 /// NM_002719 /// NM_178586 /// NM_178587 /// NM_178588 /// XM_005267819 /// XM_005267820 /// XM_005267822 /// XM_005267823 /// XM_005267824 /// XM_005267826 /// XM_005267827 "0006508 // proteolysis // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016485 // protein processing // inferred from direct assay /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // non-traceable author statement" "0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000159 // protein phosphatase type 2A complex // non-traceable author statement /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay" 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // non-traceable author statement 201878_at N25546 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N25546 /FEA=EST /DB_XREF=gi:1139894 /DB_XREF=est:yx76e05.s1 /CLONE=IMAGE:267680 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2" N25546 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201879_at AI694332 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI694332 /FEA=EST /DB_XREF=gi:4971672 /DB_XREF=est:wd45e11.x1 /CLONE=IMAGE:2331116 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2" AI694332 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201880_at AL040708 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL040708 /FEA=EST /DB_XREF=gi:5409654 /DB_XREF=est:DKFZp434A1015_s1 /CLONE=DKFZp434A1015 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2" AL040708 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201881_s_at NM_005744 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005744.2 /DEF=Homo sapiens ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 (ARIH1), mRNA. /FEA=mRNA /GEN=ARIH1 /PROD=ariadne homolog /DB_XREF=gi:9966762 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2" NM_005744 ariadne RBR E3 ubiquitin protein ligase 1 ARIH1 25820 NM_005744 /// XM_006720460 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201882_x_at AI492393 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI492393 /FEA=EST /DB_XREF=gi:4393396 /DB_XREF=est:ti27e03.x1 /CLONE=IMAGE:2131708 /UG=Hs.198248 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 /FL=gb:NM_001497.1 gb:D29805.1" AI492393 "UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1" B4GALT1 2683 NM_001497 /// XM_005251440 0002064 // epithelial cell development // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005989 // lactose biosynthetic process // inferred from electronic annotation /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009312 // oligosaccharide biosynthetic process // non-traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051270 // regulation of cellular component movement // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030112 // glycocalyx // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0003945 // N-acetyllactosamine synthase activity // inferred from direct assay /// 0004461 // lactose synthase activity // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0035250 // UDP-galactosyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from physical interaction" 201883_s_at D29805 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D29805.1 /DEF=Human mRNA for beta-1,4-galactosyltransferase, complete cds. /FEA=mRNA /PROD=beta-1,4-galactosyltransferase /DB_XREF=gi:474986 /UG=Hs.198248 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 /FL=gb:NM_001497.1 gb:D29805.1" D29805 "UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1" B4GALT1 2683 NM_001497 /// XM_005251440 0002064 // epithelial cell development // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005989 // lactose biosynthetic process // inferred from electronic annotation /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009101 // glycoprotein biosynthetic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from direct assay /// 0009312 // oligosaccharide biosynthetic process // non-traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032504 // multicellular organism reproduction // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045136 // development of secondary sexual characteristics // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051270 // regulation of cellular component movement // inferred from electronic annotation /// 0060046 // regulation of acrosome reaction // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation 0000138 // Golgi trans cisterna // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0030112 // glycocalyx // inferred from direct assay /// 0031526 // brush border membrane // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003831 // beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity // inferred from direct assay /// 0003945 // N-acetyllactosamine synthase activity // inferred from direct assay /// 0004461 // lactose synthase activity // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008378 // galactosyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0035250 // UDP-galactosyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043014 // alpha-tubulin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from physical interaction" 201884_at NM_004363 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004363.1 /DEF=Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), mRNA. /FEA=mRNA /GEN=CEACAM5 /PROD=carcinoembryonic antigen-related cell adhesionmolecule 5 /DB_XREF=gi:11386170 /UG=Hs.220529 carcinoembryonic antigen-related cell adhesion molecule 5 /FL=gb:NM_004363.1 gb:M29540.1" NM_004363 carcinoembryonic antigen-related cell adhesion molecule 5 CEACAM5 1048 NM_001291484 /// NM_004363 /// XM_005258413 /// XM_005258415 0010832 // negative regulation of myotube differentiation // inferred from direct assay /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071575 // integral component of external side of plasma membrane // inferred from direct assay 0034235 // GPI anchor binding // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 201885_s_at NM_000398 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000398.3 /DEF=Homo sapiens diaphorase (NADH) (cytochrome b-5 reductase) (DIA1), nuclear gene encoding mitochondrial protein, transcript variant M, mRNA. /FEA=mRNA /GEN=DIA1 /PROD=cytochrome b5 reductase, membrane-bound isoform /DB_XREF=gi:6552326 /UG=Hs.274464 diaphorase (NADH) (cytochrome b-5 reductase) /FL=gb:BC004821.1 gb:NM_000398.3" NM_000398 cytochrome b5 reductase 3 CYB5R3 1727 NM_000398 /// NM_001129819 /// NM_001171660 /// NM_001171661 /// NM_007326 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // traceable author statement /// 0016208 // AMP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from direct assay" 201886_at NM_025230 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_025230.1 /DEF=Homo sapiens hypthetical protein PRO2389 (PRO2389), mRNA. /FEA=mRNA /GEN=PRO2389 /PROD=hypthetical protein PRO2389 /DB_XREF=gi:13489107 /UG=Hs.283976 hypthetical protein PRO2389 /FL=gb:AF130070.1 gb:AF267858.1 gb:NM_025230.1" NM_025230 DDB1 and CUL4 associated factor 11 DCAF11 80344 NM_001163484 /// NM_025230 /// NM_181357 /// NR_028099 /// NR_028100 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201887_at NM_001560 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001560.1 /DEF=Homo sapiens interleukin 13 receptor, alpha 1 (IL13RA1), mRNA. /FEA=mRNA /GEN=IL13RA1 /PROD=interleukin 13 receptor, alpha 1 /DB_XREF=gi:4504646 /UG=Hs.285115 interleukin 13 receptor, alpha 1 /FL=gb:NM_001560.1 gb:U81379.3" NM_001560 "interleukin 13 receptor, alpha 1" IL13RA1 3597 NM_001560 /// XM_005262411 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0035772 // interleukin-13-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005898 // interleukin-13 receptor complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016515 // interleukin-13 receptor activity // inferred from electronic annotation 201888_s_at U81379 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U81379.3 /DEF=Homo sapiens interleukin-13 receptor mRNA, complete cds. /FEA=mRNA /PROD=interleukin-13 receptor /DB_XREF=gi:5870850 /UG=Hs.285115 interleukin 13 receptor, alpha 1 /FL=gb:NM_001560.1 gb:U81379.3" U81379 "interleukin 13 receptor, alpha 1" IL13RA1 3597 NM_001560 /// XM_005262411 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0035772 // interleukin-13-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005898 // interleukin-13 receptor complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016515 // interleukin-13 receptor activity // inferred from electronic annotation 201889_at NM_014888 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014888.1 /DEF=Homo sapiens predicted osteoblast protein (GS3786), mRNA. /FEA=mRNA /GEN=GS3786 /PROD=predicted osteoblast protein /DB_XREF=gi:7661713 /UG=Hs.29882 predicted osteoblast protein /FL=gb:D87120.1 gb:NM_014888.1" NM_014888 "family with sequence similarity 3, member C" FAM3C 10447 NM_001040020 /// NM_014888 0007275 // multicellular organismal development // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005125 // cytokine activity // non-traceable author statement 201890_at BE966236 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE966236 /FEA=EST /DB_XREF=gi:11771437 /DB_XREF=est:601660172R1 /CLONE=IMAGE:3905920 /UG=Hs.75319 ribonucleotide reductase M2 polypeptide /FL=gb:NM_001034.1 BE966236 ribonucleotide reductase M2 RRM2 6241 NM_001034 /// NM_001165931 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009186 // deoxyribonucleoside diphosphate metabolic process // inferred from electronic annotation /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from sequence or structural similarity /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement "0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // inferred from sequence or structural similarity /// 0004748 // ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation" 201891_s_at NM_004048 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004048.1 /DEF=Homo sapiens beta-2-microglobulin (B2M), mRNA. /FEA=mRNA /GEN=B2M /PROD=beta-2-microglobulin /DB_XREF=gi:4757825 /UG=Hs.75415 beta-2-microglobulin /FL=gb:AB021288.1 gb:NM_004048.1" NM_004048 beta-2-microglobulin B2M 567 NM_004048 /// XM_005254549 /// XM_006725182 "0001895 // retina homeostasis // inferred from expression pattern /// 0001916 // positive regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0002481 // antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0042026 // protein refolding // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0031901 // early endosome membrane // traceable author statement /// 0031905 // early endosome lumen // traceable author statement /// 0042612 // MHC class I protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 201892_s_at NM_000884 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000884.1 /DEF=Homo sapiens IMP (inosine monophosphate) dehydrogenase 2 (IMPDH2), mRNA. /FEA=mRNA /GEN=IMPDH2 /PROD=IMP (inosine monophosphate) dehydrogenase 2 /DB_XREF=gi:4504688 /UG=Hs.75432 IMP (inosine monophosphate) dehydrogenase 2 /FL=gb:J04208.1 gb:NM_000884.1" NM_000884 IMP (inosine 5'-monophosphate) dehydrogenase 2 IMPDH2 3615 NM_000884 /// XM_006713128 0006051 // N-acetylmannosamine metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006177 // GMP biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046651 // lymphocyte proliferation // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003938 // IMP dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0018580 // nitronate monooxygenase activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047465 // N-acylglucosamine-6-phosphate 2-epimerase activity // inferred from electronic annotation 201893_x_at AF138300 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF138300.1 /DEF=Homo sapiens decorin variant A mRNA, complete cds. /FEA=CDS /PROD=decorin variant A /DB_XREF=gi:5532410 /UG=Hs.76152 decorin /FL=gb:M14219.1 gb:NM_001920.1 gb:AF138300.1 gb:AF138304.1" AF138300 decorin DCN 1634 NM_001920 /// NM_133503 /// NM_133504 /// NM_133505 /// NM_133506 /// NM_133507 /// XM_005268693 /// XM_006719270 0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201894_s_at NM_001920 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001920.1 /DEF=Homo sapiens decorin (DCN), mRNA. /FEA=mRNA /GEN=DCN /PROD=decorin /DB_XREF=gi:4503270 /UG=Hs.76152 decorin /FL=gb:M14219.1 gb:NM_001920.1 gb:AF138300.1 gb:AF138304.1" NM_001920 "signal sequence receptor, alpha" SSR1 6745 NM_001292008 /// NM_003144 /// NR_120448 0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 201895_at NM_001654 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001654.1 /DEF=Homo sapiens v-raf murine sarcoma 3611 viral oncogene homolog 1 (ARAF1), mRNA. /FEA=mRNA /GEN=ARAF1 /PROD=v-raf murine sarcoma 3611 viral oncogene homolog1 /DB_XREF=gi:4502192 /UG=Hs.77183 v-raf murine sarcoma 3611 viral oncogene homolog 1 /FL=gb:BC002466.1 gb:NM_001654.1" NM_001654 "A-Raf proto-oncogene, serine/threonine kinase" ARAF 369 NM_001256196 /// NM_001256197 /// NM_001654 /// XM_006724529 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032006 // regulation of TOR signaling // inferred from mutant phenotype /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201896_s_at BC001425 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001425.1 /DEF=Homo sapiens, Similar to differential display and activated by p53, clone MGC:1780, mRNA, complete cds. /FEA=mRNA /PROD=Similar to differential display and activated byp53 /DB_XREF=gi:12655140 /UG=Hs.77550 CDC28 protein kinase 1 /FL=gb:BC001425.1 gb:AF274941.1 gb:AF279897.1 gb:NM_001826.1" BC001425 proline/serine-rich coiled-coil 1 PSRC1 84722 NM_001005290 /// NM_001032290 /// NM_001032291 /// NM_032636 /// XM_005271282 /// XM_005271283 /// XM_006710982 /// XM_006710983 /// XM_006710984 /// XM_006710985 "0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007080 // mitotic metaphase plate congression // inferred from direct assay /// 0009987 // cellular process // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0031116 // positive regulation of microtubule polymerization // inferred from sequence or structural similarity /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0060236 // regulation of mitotic spindle organization // inferred from direct assay" 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005819 // spindle // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0030496 // midbody // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity 201897_s_at NM_001826 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001826.1 /DEF=Homo sapiens CDC28 protein kinase 1 (CKS1), mRNA. /FEA=mRNA /GEN=CKS1 /PROD=CDC28 protein kinase 1 /DB_XREF=gi:4502856 /UG=Hs.77550 CDC28 protein kinase 1 /FL=gb:BC001425.1 gb:AF274941.1 gb:AF279897.1 gb:NM_001826.1" NM_001826 CDC28 protein kinase regulatory subunit 1B CKS1B 1163 NM_001826 /// NR_024163 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation 201898_s_at AI126625 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI126625 /FEA=EST /DB_XREF=gi:3595139 /DB_XREF=est:qd83a12.x1 /CLONE=IMAGE:1736062 /UG=Hs.80612 ubiquitin-conjugating enzyme E2A (RAD6 homolog) /FL=gb:M74524.1 gb:NM_003336.1 AI126625 ubiquitin-conjugating enzyme E2A UBE2A 7319 NM_001282161 /// NM_003336 /// NM_181762 /// NM_181777 0000209 // protein polyubiquitination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from genetic interaction /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201899_s_at NM_003336 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003336.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2A (RAD6 homolog) (UBE2A), mRNA. /FEA=mRNA /GEN=UBE2A /PROD=ubiquitin-conjugating enzyme E2A (RAD6 homolog) /DB_XREF=gi:4507768 /UG=Hs.80612 ubiquitin-conjugating enzyme E2A (RAD6 homolog) /FL=gb:M74524.1 gb:NM_003336.1" NM_003336 ubiquitin-conjugating enzyme E2A UBE2A 7319 NM_001282161 /// NM_003336 /// NM_181762 /// NM_181777 0000209 // protein polyubiquitination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from genetic interaction /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 201900_s_at NM_006066 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006066.1 /DEF=Homo sapiens aldo-keto reductase family 1, member A1 (aldehyde reductase) (AKR1A1), mRNA. /FEA=mRNA /GEN=AKR1A1 /PROD=aldo-keto reductase family 1, member A1(aldehyde reductase) /DB_XREF=gi:5174390 /UG=Hs.89529 aldo-keto reductase family 1, member A1 (aldehyde reductase) /FL=gb:BC000670.1 gb:J04794.1 gb:NM_006066.1" NM_006066 "aldo-keto reductase family 1, member A1 (aldehyde reductase)" AKR1A1 10327 NM_001202413 /// NM_001202414 /// NM_006066 /// NM_153326 0006006 // glucose metabolic process // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0019853 // L-ascorbic acid biosynthetic process // inferred from electronic annotation /// 0042840 // D-glucuronate catabolic process // inferred from electronic annotation /// 0046185 // aldehyde catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004032 // alditol:NADP+ 1-oxidoreductase activity // traceable author statement /// 0008106 // alcohol dehydrogenase (NADP+) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047939 // L-glucuronate reductase activity // inferred from electronic annotation 201901_s_at Z14077 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:Z14077.1 /DEF=H.sapiens mRNA for YY1NF-E1 protein. /FEA=mRNA /PROD=YY1 NF-E1 /DB_XREF=gi:38010 /UG=Hs.97496 YY1 transcription factor /FL=gb:M77698.1 gb:M76541.1 gb:NM_003403.2 Z14077 YY1 transcription factor YY1 7528 NM_003403 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006403 // RNA localization // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from electronic annotation 0000400 // four-way junction DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201902_s_at BG390664 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG390664 /FEA=EST /DB_XREF=gi:13284112 /DB_XREF=est:602415258F1 /CLONE=IMAGE:4523487 /UG=Hs.97496 YY1 transcription factor /FL=gb:M77698.1 gb:M76541.1 gb:NM_003403.2 BG390664 YY1 transcription factor YY1 7528 NM_003403 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006403 // RNA localization // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034696 // response to prostaglandin F // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031011 // Ino80 complex // inferred from direct assay /// 0031519 // PcG protein complex // inferred from electronic annotation 0000400 // four-way junction DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201903_at NM_003365 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003365.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase core protein I (UQCRC1), mRNA. /FEA=mRNA /GEN=UQCRC1 /PROD=ubiquinol-cytochrome c reductase core protein I /DB_XREF=gi:4507840 /UG=Hs.119251 ubiquinol-cytochrome c reductase core protein I /FL=gb:L16842.1 gb:NM_003365.1 gb:D26485.1" NM_003365 ubiquinol-cytochrome c reductase core protein I UQCRC1 7384 NM_003365 "0006119 // oxidative phosphorylation // traceable author statement /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0014823 // response to activity // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // traceable author statement" 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008121 // ubiquinol-cytochrome-c reductase activity // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201904_s_at BF031714 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF031714 /FEA=EST /DB_XREF=gi:10739426 /DB_XREF=est:601558023F1 /CLONE=IMAGE:3827909 /UG=Hs.147189 HYA22 protein /FL=gb:D88153.1 gb:NM_005808.1 BF031714 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like" CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201905_s_at BF590317 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF590317 /FEA=EST /DB_XREF=gi:11682641 /DB_XREF=est:nab22h04.x1 /CLONE=IMAGE:3266910 /UG=Hs.147189 HYA22 protein /FL=gb:D88153.1 gb:NM_005808.1 BF590317 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like" CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201906_s_at NM_005808 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005808.1 /DEF=Homo sapiens HYA22 protein (HYA22), mRNA. /FEA=mRNA /GEN=HYA22 /PROD=HYA22 protein /DB_XREF=gi:5031774 /UG=Hs.147189 HYA22 protein /FL=gb:D88153.1 gb:NM_005808.1" NM_005808 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like" CTDSPL 10217 NM_001008392 /// NM_005808 /// XM_006712922 /// XM_006712923 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201907_x_at U49262 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U49262.1 /DEF=Human dishevelled (DVL) mRNA, complete cds. /FEA=mRNA /GEN=DVL /PROD=dishevelled /DB_XREF=gi:1277022 /UG=Hs.174044 dishevelled 3 (homologous to Drosophila dsh) /FL=gb:U49262.1 gb:D86963.1 gb:U75651.1 gb:AF006013.1 gb:NM_004423.2" U49262 dishevelled segment polarity protein 3 DVL3 1857 NM_004423 /// XM_005247172 "0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035567 // non-canonical Wnt signaling pathway // inferred from mutant phenotype /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060026 // convergent extension // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // not recorded 0002020 // protease binding // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 201908_at NM_004423 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004423.2 /DEF=Homo sapiens dishevelled 3 (homologous to Drosophila dsh) (DVL3), mRNA. /FEA=mRNA /GEN=DVL3 /PROD=dishevelled 3 /DB_XREF=gi:6806886 /UG=Hs.174044 dishevelled 3 (homologous to Drosophila dsh) /FL=gb:U49262.1 gb:D86963.1 gb:U75651.1 gb:AF006013.1 gb:NM_004423.2" NM_004423 dishevelled segment polarity protein 3 DVL3 1857 NM_004423 /// XM_005247172 "0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035567 // non-canonical Wnt signaling pathway // inferred from mutant phenotype /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060026 // convergent extension // not recorded /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005938 // cell cortex // not recorded 0002020 // protease binding // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 201909_at NM_001008 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001008.1 /DEF=Homo sapiens ribosomal protein S4, Y-linked (RPS4Y), mRNA. /FEA=mRNA /GEN=RPS4Y /PROD=ribosomal protein S4, Y-linked /DB_XREF=gi:4506726 /UG=Hs.180911 ribosomal protein S4, Y-linked /FL=gb:M58459.1 gb:NM_001008.1 gb:AF116711.1" NM_001008 "ribosomal protein S4, Y-linked 1" RPS4Y1 6192 NM_001008 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005844 // polysome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from mutant phenotype /// 0019843 // rRNA binding // inferred from electronic annotation 201910_at BF213279 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF213279 /FEA=EST /DB_XREF=gi:11106865 /DB_XREF=est:601844779F1 /CLONE=IMAGE:4070203 /UG=Hs.183738 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) /FL=gb:AB008430.1 gb:NM_005766.1" BF213279 "FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)" FARP1 10160 NM_001001715 /// NM_001286839 /// NM_005766 /// XM_006719913 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0048365 // Rac GTPase binding // inferred from electronic annotation 201911_s_at NM_005766 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005766.1 /DEF=Homo sapiens FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) (FARP1), mRNA. /FEA=mRNA /GEN=FARP1 /PROD=FERM, RhoGEF, and pleckstrin domain protein 1 /DB_XREF=gi:5031632 /UG=Hs.183738 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) /FL=gb:AB008430.1 gb:NM_005766.1" NM_005766 "FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)" FARP1 10160 NM_001001715 /// NM_001286839 /// NM_005766 /// XM_006719913 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0048365 // Rac GTPase binding // inferred from electronic annotation 201912_s_at NM_002094 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002094.1 /DEF=Homo sapiens G1 to S phase transition 1 (GSPT1), mRNA. /FEA=mRNA /GEN=GSPT1 /PROD=G1 to S phase transition 1 /DB_XREF=gi:4504166 /UG=Hs.2707 G1 to S phase transition 1 /FL=gb:NM_002094.1" NM_002094 G1 to S phase transition 1 GSPT1 2935 NM_001130006 /// NM_001130007 /// NM_002094 /// XM_005255274 /// XM_005255275 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from mutant phenotype /// 0006479 // protein methylation // inferred from direct assay" 0005622 // intracellular // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003747 // translation release factor activity // inferred from mutant phenotype /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201913_s_at NM_025233 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_025233.1 /DEF=Homo sapiens nucleotide binding protein (NBP), mRNA. /FEA=mRNA /GEN=NBP /PROD=nucleotide binding protein /DB_XREF=gi:13376837 /UG=Hs.296422 nucleotide binding protein /FL=gb:NM_025233.1 gb:AF208536.1" NM_025233 CoA synthase COASY 80347 NM_001042529 /// NM_001042530 /// NM_001042531 /// NM_001042532 /// NM_025233 /// XM_006722116 /// XR_429926 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009108 // coenzyme biosynthetic process // traceable author statement /// 0015937 // coenzyme A biosynthetic process // inferred from direct assay /// 0015937 // coenzyme A biosynthetic process // inferred from electronic annotation /// 0015937 // coenzyme A biosynthetic process // traceable author statement /// 0015939 // pantothenate metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004140 // dephospho-CoA kinase activity // inferred from direct assay /// 0004595 // pantetheine-phosphate adenylyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 201914_s_at AK001465 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK001465.1 /DEF=Homo sapiens cDNA FLJ10603 fis, clone NT2RP2005012, highly similar to Homo sapiens mRNA for SEC63 protein. /FEA=mRNA /DB_XREF=gi:7022740 /UG=Hs.31575 SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like /FL=gb:AF100141.1 gb:NM_007214.1" AK001465 SEC63 homolog (S. cerevisiae) SEC63 11231 NM_007214 /// NM_018529 "0001889 // liver development // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from mutant phenotype /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031204 // posttranslational protein targeting to membrane, translocation // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201915_at AI806665 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI806665 /FEA=EST /DB_XREF=gi:5393231 /DB_XREF=est:wf35c05.x1 /CLONE=IMAGE:2357576 /UG=Hs.31575 SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like /FL=gb:AF100141.1 gb:NM_007214.1" AI806665 SEC63 homolog (S. cerevisiae) SEC63 11231 NM_007214 /// NM_018529 "0001889 // liver development // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from mutant phenotype /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031204 // posttranslational protein targeting to membrane, translocation // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201916_s_at NM_007214 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007214.1 /DEF=Homo sapiens SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like (SEC63L), mRNA. /FEA=mRNA /GEN=SEC63L /PROD=SEC63, endoplasmic reticulum transloconcomponent (S. cerevisiae) like /DB_XREF=gi:6005871 /UG=Hs.31575 SEC63, endoplasmic reticulum translocon component (S. cerevisiae) like /FL=gb:AF100141.1 gb:NM_007214.1" NM_007214 SEC63 homolog (S. cerevisiae) SEC63 11231 NM_007214 /// NM_018529 "0001889 // liver development // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from mutant phenotype /// 0006620 // posttranslational protein targeting to membrane // inferred from mutant phenotype /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031204 // posttranslational protein targeting to membrane, translocation // inferred from electronic annotation /// 0072001 // renal system development // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 201917_s_at AI694452 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI694452 /FEA=EST /DB_XREF=gi:4971792 /DB_XREF=est:wd83h07.x1 /CLONE=IMAGE:2338237 /UG=Hs.42484 hypothetical protein FLJ10618 /FL=gb:NM_018155.1 AI694452 "solute carrier family 25 (pyrimidine nucleotide carrier ), member 36" SLC25A36 55186 NM_001104647 /// NM_018155 /// XM_005247575 /// XM_006713685 0006810 // transport // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201918_at AI927944 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI927944 /FEA=EST /DB_XREF=gi:5663908 /DB_XREF=est:wp03g05.x1 /CLONE=IMAGE:2463800 /UG=Hs.42484 hypothetical protein FLJ10618 /FL=gb:NM_018155.1 AI927944 "solute carrier family 25 (pyrimidine nucleotide carrier ), member 36" SLC25A36 55186 NM_001104647 /// NM_018155 /// XM_005247575 /// XM_006713685 0006810 // transport // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201919_at AL049246 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL049246.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564C053 (from clone DKFZp564C053). /FEA=mRNA /DB_XREF=gi:4499983 /UG=Hs.42484 hypothetical protein FLJ10618 /FL=gb:NM_018155.1 AL049246 "solute carrier family 25 (pyrimidine nucleotide carrier ), member 36" SLC25A36 55186 NM_001104647 /// NM_018155 /// XM_005247575 /// XM_006713685 0006810 // transport // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 201920_at NM_005415 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005415.2 /DEF=Homo sapiens solute carrier family 20 (phosphate transporter), member 1 (SLC20A1), mRNA. /FEA=mRNA /GEN=SLC20A1 /PROD=solute carrier family 20 (phosphatetransporter), member 1 /DB_XREF=gi:7382462 /UG=Hs.78452 solute carrier family 20 (phosphate transporter), member 1 /FL=gb:L20859.1 gb:NM_005415.2" NM_005415 "solute carrier family 20 (phosphate transporter), member 1" SLC20A1 6574 NM_005415 /// XM_005263743 /// XM_006712712 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0035435 // phosphate ion transmembrane transport // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0004872 // receptor activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0005316 // high affinity inorganic phosphate:sodium symporter activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 201921_at NM_004125 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004125.1 /DEF=Homo sapiens guanine nucleotide binding protein 10 (GNG10), mRNA. /FEA=mRNA /GEN=GNG10 /PROD=guanine nucleotide binding protein 10 /DB_XREF=gi:4758445 /UG=Hs.79126 guanine nucleotide binding protein 10 /FL=gb:NM_004125.1 gb:U31383.1" NM_004125 "guanine nucleotide binding protein (G protein), gamma 10" GNG10 2790 NM_001017998 /// NM_001198664 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation 201922_at NM_014886 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014886.1 /DEF=Homo sapiens hypothetical protein (YR-29), mRNA. /FEA=mRNA /GEN=YR-29 /PROD=hypothetical protein /DB_XREF=gi:7662676 /UG=Hs.8170 hypothetical protein /FL=gb:AF077615.1 gb:BC005288.1 gb:NM_014886.1" NM_014886 NSA2 ribosome biogenesis homolog (S. cerevisiae) NSA2 10412 NM_001271665 /// NM_014886 /// NR_073403 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 201923_at NM_006406 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006406.1 /DEF=Homo sapiens thioredoxin peroxidase (antioxidant enzyme) (AOE372), mRNA. /FEA=mRNA /GEN=AOE372 /PROD=thioredoxin peroxidase /DB_XREF=gi:5453548 /UG=Hs.83383 thioredoxin peroxidase (antioxidant enzyme) /FL=gb:BC003609.1 gb:NM_006406.1 gb:U25182.1" NM_006406 peroxiredoxin 4 PRDX4 10549 NM_006406 /// XM_005274438 0007252 // I-kappaB phosphorylation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000255 // negative regulation of male germ cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008379 // thioredoxin peroxidase activity // traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201924_at NM_005935 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005935.1 /DEF=Homo sapiens myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 (MLLT2), mRNA. /FEA=mRNA /GEN=MLLT2 /PROD=myeloidlymphoid or mixed-lineage leukemia(trithorax (Drosophila) homolog); translocated to, 2 /DB_XREF=gi:5174572 /UG=Hs.114765 myeloidlymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2 /FL=gb:L13773.1 gb:L25050.1 gb:NM_005935.1" NM_005935 "AF4/FMR2 family, member 1" AFF1 4299 NM_001166693 /// NM_005935 /// XM_005263007 /// XM_005263008 /// XM_005263009 /// XM_005263010 /// XM_005263011 /// XM_005263012 /// XM_005263013 "0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201925_s_at NM_000574 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000574.1 /DEF=Homo sapiens decay accelerating factor for complement (CD55, Cromer blood group system) (DAF), mRNA. /FEA=mRNA /GEN=DAF /PROD=decay accelerating factor for complement (CD55,Cromer blood group system) /DB_XREF=gi:10835142 /UG=Hs.1369 decay accelerating factor for complement (CD55, Cromer blood group system) /FL=gb:NM_000574.1 gb:BC001288.1 gb:M31516.1" NM_000574 "CD55 molecule, decay accelerating factor for complement (Cromer blood group)" CD55 1604 NM_000574 /// NM_001114543 /// NM_001114544 /// NM_001114752 /// XM_005273077 "0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0035743 // CD4-positive, alpha-beta T cell cytokine production // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // non-traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 2000516 // positive regulation of CD4-positive, alpha-beta T cell activation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 201926_s_at BC001288 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001288.1 /DEF=Homo sapiens, Similar to decay accelerating factor for complement (CD55, Cromer blood group system), clone MGC:5192, mRNA, complete cds. /FEA=mRNA /PROD=Similar to decay accelerating factor forcomplement (CD55, Cromer blood group system) /DB_XREF=gi:12654888 /UG=Hs.1369 decay accelerating factor for complement (CD55, Cromer blood group system) /FL=gb:NM_000574.1 gb:BC001288.1 gb:M31516.1" BC001288 "CD55 molecule, decay accelerating factor for complement (Cromer blood group)" CD55 1604 NM_000574 /// NM_001114543 /// NM_001114544 /// NM_001114752 /// XM_005273077 "0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0035743 // CD4-positive, alpha-beta T cell cytokine production // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // non-traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 2000516 // positive regulation of CD4-positive, alpha-beta T cell activation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 201927_s_at BG292559 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG292559 /FEA=EST /DB_XREF=gi:13051484 /DB_XREF=est:602386951F1 /CLONE=IMAGE:4515829 /UG=Hs.152151 plakophilin 4 /FL=gb:NM_003628.2 BG292559 plakophilin 4 PKP4 8502 NM_001005476 /// NM_003628 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201928_at AA194254 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA194254 /FEA=EST /DB_XREF=gi:1783969 /DB_XREF=est:zr39d09.s1 /CLONE=IMAGE:665777 /UG=Hs.152151 plakophilin 4 /FL=gb:NM_003628.2 AA194254 plakophilin 4 PKP4 8502 NM_001005476 /// NM_003628 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201929_s_at NM_003628 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003628.2 /DEF=Homo sapiens plakophilin 4 (PKP4), mRNA. /FEA=mRNA /GEN=PKP4 /PROD=plakophilin 4 /DB_XREF=gi:6806894 /UG=Hs.152151 plakophilin 4 /FL=gb:NM_003628.2" NM_003628 plakophilin 4 PKP4 8502 NM_001005476 /// NM_003628 0007043 // cell-cell junction assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201930_at NM_005915 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005915.2 /DEF=Homo sapiens minichromosome maintenance deficient (mis5, S. pombe) 6 (MCM6), mRNA. /FEA=mRNA /GEN=MCM6 /PROD=minichromosome maintenance deficient (mis5, S.pombe) 6 /DB_XREF=gi:7427518 /UG=Hs.155462 minichromosome maintenance deficient (mis5, S. pombe) 6 /FL=gb:U46838.1 gb:D84557.1 gb:NM_005915.2" NM_005915 minichromosome maintenance complex component 6 MCM6 4175 NM_005915 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201931_at NM_000126 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000126.1 /DEF=Homo sapiens electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) (ETFA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ETFA /PROD=electron transfer flavoprotein, alphapolypeptide /DB_XREF=gi:4503606 /UG=Hs.169919 electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) /FL=gb:J04058.1 gb:NM_000126.1" NM_000126 "electron-transfer-flavoprotein, alpha polypeptide" ETFA 2108 NM_000126 /// NM_001127716 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay 201932_at NM_006369 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006369.1 /DEF=Homo sapiens MUF1 protein (MUF1), mRNA. /FEA=mRNA /GEN=MUF1 /PROD=MUF1 protein /DB_XREF=gi:5453747 /UG=Hs.172210 MUF1 protein /FL=gb:BC004953.1 gb:NM_006369.1" NM_006369 leucine rich repeat containing 41 LRRC41 10489 NM_006369 /// XM_005270376 0016567 // protein ubiquitination // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 201933_at NM_002768 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002768.1 /DEF=Homo sapiens procollagen (type III) N-endopeptidase (PCOLN3), mRNA. /FEA=mRNA /GEN=PCOLN3 /PROD=procollagen (type III) N-endopeptidase /DB_XREF=gi:4506138 /UG=Hs.183138 procollagen (type III) N-endopeptidase /FL=gb:U58048.1 gb:NM_002768.1 gb:AF281063.1" NM_002768 charged multivesicular body protein 1A CHMP1A 5119 NM_001083314 /// NM_002768 /// NR_046418 "0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0016458 // gene silencing // inferred from direct assay /// 0045014 // negative regulation of transcription by glucose // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation" 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 201934_at N92524 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N92524 /FEA=EST /DB_XREF=gi:1264833 /DB_XREF=est:zb28d02.s1 /CLONE=IMAGE:304899 /UG=Hs.194110 hypothetical protein PRO2730 /FL=gb:AF132207.1 gb:NM_025222.1 N92524 WD repeat domain 82 WDR82 80335 NM_025222 0051568 // histone H3-K4 methylation // inferred from direct assay 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0072357 // PTW/PP1 phosphatase complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay 201935_s_at AI768122 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI768122 /FEA=EST /DB_XREF=gi:5234631 /DB_XREF=est:wg81d04.x1 /CLONE=IMAGE:2371495 /UG=Hs.25732 eukaryotic translation initiation factor 4 gamma, 3 /FL=gb:NM_003760.2 gb:AF012072.2" AI768122 "eukaryotic translation initiation factor 4 gamma, 3" EIF4G3 8672 NM_001198801 /// NM_001198802 /// NM_001198803 /// NM_003760 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement "0000339 // RNA cap binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201936_s_at NM_003760 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003760.2 /DEF=Homo sapiens eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), mRNA. /FEA=mRNA /GEN=EIF4G3 /PROD=eukaryotic translation initiation factor 4gamma, 3 /DB_XREF=gi:10092600 /UG=Hs.25732 eukaryotic translation initiation factor 4 gamma, 3 /FL=gb:NM_003760.2 gb:AF012072.2" NM_003760 "eukaryotic translation initiation factor 4 gamma, 3" EIF4G3 8672 NM_001198801 /// NM_001198802 /// NM_001198803 /// NM_003760 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0060903 // positive regulation of meiosis I // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement "0000339 // RNA cap binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 201937_s_at NM_012100 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012100.1 /DEF=Homo sapiens aspartyl aminopeptidase (DNPEP), mRNA. /FEA=mRNA /GEN=DNPEP /PROD=aspartyl aminopeptidase /DB_XREF=gi:6912247 /UG=Hs.258551 aspartyl aminopeptidase /FL=gb:BC000653.1 gb:AF005050.2 gb:NM_012100.1" NM_012100 aspartyl aminopeptidase DNPEP 23549 NM_012100 /// XM_005246430 /// XM_005246431 /// XM_005246432 0006508 // proteolysis // inferred from electronic annotation /// 0006518 // peptide metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201938_at NM_004642 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004642.1 /DEF=Homo sapiens deleted in oral cancer (mouse, homolog) 1 (DOC1), mRNA. /FEA=mRNA /GEN=DOC1 /PROD=deleted in oral cancer (mouse, homolog) 1 /DB_XREF=gi:4758187 /UG=Hs.3436 deleted in oral cancer (mouse, homolog) 1 /FL=gb:AB006077.1 gb:AF006484.1 gb:NM_004642.1" NM_004642 cyclin-dependent kinase 2 associated protein 1 CDK2AP1 8099 NM_001270433 /// NM_001270434 /// NM_004642 /// NR_073007 /// NR_073008 0000084 // mitotic S phase // traceable author statement /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement 0003677 // DNA binding // traceable author statement 201939_at NM_006622 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006622.1 /DEF=Homo sapiens serum-inducible kinase (SNK), mRNA. /FEA=mRNA /GEN=SNK /PROD=serum-inducible kinase /DB_XREF=gi:5730054 /UG=Hs.3838 serum-inducible kinase /FL=gb:AF059617.1 gb:NM_006622.1 gb:AF223574.1" NM_006622 polo-like kinase 2 PLK2 10769 NM_001252226 /// NM_006622 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // inferred from sequence or structural similarity /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007613 // memory // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032486 // Rap protein signal transduction // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0046599 // regulation of centriole replication // inferred from direct assay /// 0046599 // regulation of centriole replication // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity 0005622 // intracellular // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 201940_at AA897514 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA897514 /FEA=EST /DB_XREF=gi:3034134 /DB_XREF=est:aj62b12.s1 /CLONE=IMAGE:1394879 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2 AA897514 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201941_at BE349147 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE349147 /FEA=EST /DB_XREF=gi:9261086 /DB_XREF=est:ht51f05.x1 /CLONE=IMAGE:3150273 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2 BE349147 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201942_s_at D85390 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D85390.1 /DEF=Homo sapiens mRNA for gp180-carboxypeptidase D-like enzyme, complete cds. /FEA=mRNA /PROD=gp180-carboxypeptidase D-like enzyme /DB_XREF=gi:3641620 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2" D85390 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201943_s_at NM_001304 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001304.2 /DEF=Homo sapiens carboxypeptidase D (CPD), mRNA. /FEA=mRNA /GEN=CPD /PROD=carboxypeptidase D precursor /DB_XREF=gi:8051580 /UG=Hs.5057 carboxypeptidase D /FL=gb:U65090.1 gb:D85390.1 gb:NM_001304.2" NM_001304 carboxypeptidase D CPD 1362 NM_001199775 /// NM_001304 0006508 // proteolysis // inferred from electronic annotation 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201944_at NM_000521 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000521.2 /DEF=Homo sapiens hexosaminidase B (beta polypeptide) (HEXB), mRNA. /FEA=mRNA /GEN=HEXB /PROD=hexosaminidase B preproprotein /DB_XREF=gi:13128866 /UG=Hs.51043 hexosaminidase B (beta polypeptide) /FL=gb:NM_000521.2 gb:M19735.1" NM_000521 hexosaminidase B (beta polypeptide) HEXB 3074 NM_000521 /// NM_001292004 0001501 // skeletal system development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007338 // single fertilization // inferred from electronic annotation /// 0007341 // penetration of zona pellucida // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008049 // male courtship behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009313 // oligosaccharide catabolic process // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0031323 // regulation of cellular metabolic process // inferred from electronic annotation /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0042552 // myelination // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay" 201945_at NM_002569 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002569.1 /DEF=Homo sapiens paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) (PACE), mRNA. /FEA=mRNA /GEN=PACE /PROD=paired basic amino acid cleaving enzyme (furin,membrane associated receptor protein) /DB_XREF=gi:4505578 /UG=Hs.59242 paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) /FL=gb:NM_002569.1" NM_002569 furin (paired basic amino acid cleaving enzyme) FURIN 5045 NM_001289823 /// NM_001289824 /// NM_002569 /// XM_005254931 /// XM_005254932 0006465 // signal peptide processing // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0016485 // protein processing // inferred from mutant phenotype /// 0016486 // peptide hormone processing // inferred from direct assay /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0019058 // viral life cycle // inferred from expression pattern /// 0019068 // virion assembly // traceable author statement /// 0019082 // viral protein processing // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032455 // nerve growth factor processing // traceable author statement /// 0032804 // negative regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032902 // nerve growth factor production // inferred from direct assay /// 0032904 // negative regulation of nerve growth factor production // inferred from direct assay /// 0032911 // negative regulation of transforming growth factor beta1 production // inferred from mutant phenotype /// 0032940 // secretion by cell // inferred from direct assay /// 0042176 // regulation of protein catabolic process // inferred from mutant phenotype /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred by curator /// 0052548 // regulation of endopeptidase activity // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004175 // endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048406 // nerve growth factor binding // inferred from direct assay 201946_s_at AL545982 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL545982 /FEA=EST /DB_XREF=gi:12878676 /DB_XREF=est:AL545982 /CLONE=CS0DI023YD15 (5 prime) /UG=Hs.6456 chaperonin containing TCP1, subunit 2 (beta) /FL=gb:AF026293.1 gb:AF026166.1 gb:NM_006431.1" AL545982 "chaperonin containing TCP1, subunit 2 (beta)" CCT2 10576 NM_001198842 /// NM_006431 0006457 // protein folding // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from mutant phenotype 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 201947_s_at NM_006431 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006431.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 2 (beta) (CCT2), mRNA. /FEA=mRNA /GEN=CCT2 /PROD=chaperonin containing TCP1, subunit 2 (beta) /DB_XREF=gi:5453602 /UG=Hs.6456 chaperonin containing TCP1, subunit 2 (beta) /FL=gb:AF026293.1 gb:AF026166.1 gb:NM_006431.1" NM_006431 "chaperonin containing TCP1, subunit 2 (beta)" CCT2 10576 NM_001198842 /// NM_006431 0006457 // protein folding // non-traceable author statement /// 0006457 // protein folding // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051131 // chaperone-mediated protein complex assembly // inferred from mutant phenotype 0002199 // zona pellucida receptor complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 201948_at NM_013285 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013285.1 /DEF=Homo sapiens nucleolar GTPase (HUMAUANTIG), mRNA. /FEA=mRNA /GEN=HUMAUANTIG /PROD=nucleolar GTPase /DB_XREF=gi:7019418 /UG=Hs.75528 nucleolar GTPase /FL=gb:BC000107.1 gb:L05425.1 gb:NM_013285.1" NM_013285 guanine nucleotide binding protein-like 2 (nucleolar) GNL2 29889 NM_013285 0006184 // GTP catabolic process // not recorded /// 0006184 // GTP catabolic process // non-traceable author statement /// 0042254 // ribosome biogenesis // not recorded 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // non-traceable author statement /// 0005525 // GTP binding // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201949_x_at AL572341 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL572341 /FEA=EST /DB_XREF=gi:12930514 /DB_XREF=est:AL572341 /CLONE=CS0DI007YC13 (3 prime) /UG=Hs.76368 capping protein (actin filament) muscle Z-line, beta /FL=gb:NM_004930.1 gb:U03271.1" AL572341 "capping protein (actin filament) muscle Z-line, beta" CAPZB 832 NM_001206540 /// NM_001206541 /// NM_001282162 /// NM_004930 /// XM_006710938 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 201950_x_at NM_004930 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004930.1 /DEF=Homo sapiens capping protein (actin filament) muscle Z-line, beta (CAPZB), mRNA. /FEA=mRNA /GEN=CAPZB /PROD=F-actin capping protein beta subunit /DB_XREF=gi:4826658 /UG=Hs.76368 capping protein (actin filament) muscle Z-line, beta /FL=gb:NM_004930.1 gb:U03271.1" NM_004930 "capping protein (actin filament) muscle Z-line, beta" CAPZB 832 NM_001206540 /// NM_001206541 /// NM_001282162 /// NM_004930 /// XM_006710938 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation /// 0051693 // actin filament capping // inferred from electronic annotation /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071203 // WASH complex // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 201951_at BF242905 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF242905 /FEA=EST /DB_XREF=gi:11156833 /DB_XREF=est:601877949F1 /CLONE=IMAGE:4106028 /UG=Hs.10247 activated leucocyte cell adhesion molecule /FL=gb:NM_001627.1 gb:L38608.1 BF242905 activated leukocyte cell adhesion molecule ALCAM 214 NM_001243280 /// NM_001243281 /// NM_001243283 /// NM_001627 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201952_at AA156721 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA156721 /FEA=EST /DB_XREF=gi:1728335 /DB_XREF=est:zl18b04.s1 /CLONE=IMAGE:502255 /UG=Hs.10247 activated leucocyte cell adhesion molecule /FL=gb:NM_001627.1 gb:L38608.1 AA156721 activated leukocyte cell adhesion molecule ALCAM 214 NM_001243280 /// NM_001243281 /// NM_001243283 /// NM_001627 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201953_at NM_006384 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006384.2 /DEF=Homo sapiens calcium and integrin binding protein (DNA-dependent protein kinase interacting protein) (SIP2-28), mRNA. /FEA=mRNA /GEN=SIP2-28 /PROD=calcium and integrin binding protein /DB_XREF=gi:9951921 /UG=Hs.10803 calcium and integrin binding protein (DNA-dependent protein kinase interacting protein) /FL=gb:BC000846.1 gb:U83236.1 gb:U82226.1 gb:U85611.1 gb:NM_006384.2" NM_006384 calcium and integrin binding 1 (calmyrin) CIB1 10519 NM_001277764 /// NM_006384 /// NR_102427 /// NR_102428 /// XM_006720375 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002931 // response to ischemia // inferred from sequence or structural similarity /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007113 // endomitotic cell cycle // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // non-traceable author statement /// 0030220 // platelet formation // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0038163 // thrombopoietin-mediated signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045653 // negative regulation of megakaryocyte differentiation // inferred from sequence or structural similarity /// 0048554 // positive regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051302 // regulation of cell division // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070886 // positive regulation of calcineurin-NFAT signaling cascade // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from sequence or structural similarity /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from genetic interaction /// 0090050 // positive regulation of cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0090314 // positive regulation of protein targeting to membrane // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from direct assay /// 2000256 // positive regulation of male germ cell proliferation // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from mutant phenotype /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from direct assay /// 0032433 // filopodium tip // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005509 // calcium ion binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from physical interaction /// 0043495 // protein anchor // inferred from genetic interaction /// 0044325 // ion channel binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 201954_at NM_005720 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005720.1 /DEF=Homo sapiens actin related protein 23 complex, subunit 1A (41 kD) (ARPC1B), mRNA. /FEA=mRNA /GEN=ARPC1B /PROD=actin related protein 23 complex, subunit 1A(41 kD) /DB_XREF=gi:5031600 /UG=Hs.11538 actin related protein 23 complex, subunit 1A (41 kD) /FL=gb:BC002562.1 gb:AF006084.1 gb:NM_005720.1" NM_005720 "actin related protein 2/3 complex, subunit 1B, 41kDa" ARPC1B 10095 NM_005720 /// XM_006715825 /// XM_006715826 0006928 // cellular component movement // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201955_at AL137784 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL137784 /DEF=Human DNA sequence from clone RP1-199J3 on chromosome 6 Contains ESTs, STSs, GSSs and CpG islands. Contains part of the gene for a novel protein similar to ubiquitin carboxyl-terminal hudrolase 16 (EC 3.1.2.15), a novel gene, the CCNC gene encodin... /FEA=mRNA /DB_XREF=gi:9863487 /UG=Hs.118442 cyclin C /FL=gb:NM_005190.2" AL137784 cyclin C CCNC 892 NM_001013399 /// NM_005190 /// XM_005267202 /// XM_006715594 "0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation" "0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation" 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 201956_s_at NM_014236 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014236.1 /DEF=Homo sapiens glyceronephosphate O-acyltransferase (GNPAT), mRNA. /FEA=mRNA /GEN=GNPAT /PROD=glyceronephosphate O-acyltransferase /DB_XREF=gi:7657133 /UG=Hs.12482 glyceronephosphate O-acyltransferase /FL=gb:BC000450.1 gb:AF043937.1 gb:NM_014236.1" NM_014236 glyceronephosphate O-acyltransferase GNPAT 8443 NM_014236 /// XM_005273313 /// XM_005273314 0006644 // phospholipid metabolic process // traceable author statement /// 0006650 // glycerophospholipid metabolic process // inferred from electronic annotation /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008611 // ether lipid biosynthetic process // inferred from direct assay /// 0008611 // ether lipid biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0021587 // cerebellum morphogenesis // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0070542 // response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004366 // glycerol-3-phosphate O-acyltransferase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0016287 // glycerone-phosphate O-acyltransferase activity // inferred from direct assay /// 0016287 // glycerone-phosphate O-acyltransferase activity // traceable author statement /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation" 201957_at AF324888 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF324888.1 /DEF=Homo sapiens myosin phosphatase target subunit 2 mRNA, complete cds. /FEA=mRNA /PROD=myosin phosphatase target subunit 2 /DB_XREF=gi:12642661 /UG=Hs.130760 myosin phosphatase, target subunit 2 /FL=gb:AF324888.1 gb:AB003062.1 gb:NM_002481.1" AF324888 "protein phosphatase 1, regulatory subunit 12B" PPP1R12B 4660 NM_001167857 /// NM_001167858 /// NM_001197131 /// NM_002481 /// NM_032103 /// NM_032104 /// NM_032105 /// XM_005245199 /// XM_005245200 /// XM_005245201 /// XM_005245202 /// XM_005245204 /// XM_005245205 /// XM_005245206 /// XM_006711339 /// XR_426776 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement 201958_s_at NM_002481 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002481.1 /DEF=Homo sapiens myosin phosphatase, target subunit 2 (MYPT2), mRNA. /FEA=mRNA /GEN=MYPT2 /PROD=myosin phosphatase target subunit 2 /DB_XREF=gi:4505318 /UG=Hs.130760 myosin phosphatase, target subunit 2 /FL=gb:AF324888.1 gb:AB003062.1 gb:NM_002481.1" NM_002481 "protein phosphatase 1, regulatory subunit 12B" PPP1R12B 4660 NM_001167857 /// NM_001167858 /// NM_001197131 /// NM_002481 /// NM_032103 /// NM_032104 /// NM_032105 /// XM_005245199 /// XM_005245200 /// XM_005245201 /// XM_005245202 /// XM_005245204 /// XM_005245205 /// XM_005245206 /// XM_006711339 /// XR_426776 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006937 // regulation of muscle contraction // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement 201959_s_at AA488899 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA488899 /FEA=EST /DB_XREF=gi:2218501 /DB_XREF=est:aa55h06.s1 /CLONE=IMAGE:824891 /UG=Hs.151411 KIAA0916 protein /FL=gb:AF075587.1 gb:AF083244.1 gb:NM_015057.1 AA488899 "MYC binding protein 2, E3 ubiquitin protein ligase" MYCBP2 23077 NM_015057 /// XM_005266299 /// XM_005266300 /// XM_006719779 /// XM_006719780 /// XM_006719781 /// XM_006719782 /// XM_006719783 /// XM_006719784 /// XM_006719785 /// XM_006719786 /// XM_006719787 /// XM_006719788 /// XM_006719789 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0021785 // branchiomotor neuron axon guidance // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201960_s_at NM_015057 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015057.1 /DEF=Homo sapiens KIAA0916 protein (KIAA0916), mRNA. /FEA=mRNA /GEN=KIAA0916 /PROD=KIAA0916 protein /DB_XREF=gi:7662379 /UG=Hs.151411 KIAA0916 protein /FL=gb:AF075587.1 gb:AF083244.1 gb:NM_015057.1" NM_015057 "MYC binding protein 2, E3 ubiquitin protein ligase" MYCBP2 23077 NM_015057 /// XM_005266299 /// XM_005266300 /// XM_006719779 /// XM_006719780 /// XM_006719781 /// XM_006719782 /// XM_006719783 /// XM_006719784 /// XM_006719785 /// XM_006719786 /// XM_006719787 /// XM_006719788 /// XM_006719789 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0021785 // branchiomotor neuron axon guidance // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201961_s_at AL583171 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL583171 /FEA=EST /DB_XREF=gi:12951876 /DB_XREF=est:AL583171 /CLONE=CS0DL009YA21 (3 prime) /UG=Hs.153639 hypothetical SBBI03 protein /FL=gb:AF077599.1 gb:NM_005785.1 AL583171 "ring finger protein 41, E3 ubiquitin protein ligase" RNF41 10193 NM_001242826 /// NM_005785 /// NM_194358 /// NM_194359 /// NR_040053 /// XM_005268561 0000209 // protein polyubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0051896 // regulation of protein kinase B signaling // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005128 // erythropoietin receptor binding // inferred from electronic annotation /// 0005135 // interleukin-3 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031386 // protein tag // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201962_s_at NM_005785 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005785.1 /DEF=Homo sapiens hypothetical SBBI03 protein (SBB103), mRNA. /FEA=mRNA /GEN=SBB103 /PROD=hypothetical SBBI03 protein /DB_XREF=gi:5032070 /UG=Hs.153639 hypothetical SBBI03 protein /FL=gb:AF077599.1 gb:NM_005785.1" NM_005785 "ring finger protein 41, E3 ubiquitin protein ligase" RNF41 10193 NM_001242826 /// NM_005785 /// NM_194358 /// NM_194359 /// NR_040053 /// XM_005268561 0000209 // protein polyubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0043408 // regulation of MAPK cascade // inferred from direct assay /// 0045619 // regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045637 // regulation of myeloid cell differentiation // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0051896 // regulation of protein kinase B signaling // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005128 // erythropoietin receptor binding // inferred from electronic annotation /// 0005135 // interleukin-3 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031386 // protein tag // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201963_at NM_021122 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021122.2 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 2 (FACL2), mRNA. /FEA=mRNA /GEN=FACL2 /PROD=long-chain fatty-acid-Coenzyme A ligase 2 /DB_XREF=gi:12669906 /UG=Hs.154890 fatty-acid-Coenzyme A ligase, long-chain 2 /FL=gb:NM_021122.2 gb:D10040.1" NM_021122 acyl-CoA synthetase long-chain family member 1 ACSL1 2180 NM_001286708 /// NM_001286710 /// NM_001286711 /// NM_001286712 /// NM_001995 /// XM_005262827 /// XM_005262828 /// XM_005262829 /// XM_005262831 /// XM_006714138 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0033211 // adiponectin-activated signaling pathway // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0034201 // response to oleic acid // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0042178 // xenobiotic catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0044539 // long-chain fatty acid import // inferred from direct assay /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201964_at N64643 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N64643 /FEA=EST /DB_XREF=gi:1212472 /DB_XREF=est:yz87a06.s1 /CLONE=IMAGE:290002 /UG=Hs.154919 KIAA0625 protein /FL=gb:NM_015046.1 N64643 senataxin SETX 23064 NM_015046 /// XM_005272171 /// XM_005272172 /// XM_005272173 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006369 // termination of RNA polymerase II transcription // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003678 // DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201965_s_at NM_015046 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015046.1 /DEF=Homo sapiens KIAA0625 protein (KIAA0625), mRNA. /FEA=mRNA /GEN=KIAA0625 /PROD=KIAA0625 protein /DB_XREF=gi:7662211 /UG=Hs.154919 KIAA0625 protein /FL=gb:NM_015046.1" NM_015046 senataxin SETX 23064 NM_015046 /// XM_005272171 /// XM_005272172 /// XM_005272173 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006369 // termination of RNA polymerase II transcription // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003678 // DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201966_at NM_004550 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004550.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Q reductase) (NDUFS2), mRNA. /FEA=mRNA /GEN=NDUFS2 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 2(49kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758785 /UG=Hs.173611 NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD) (NADH-coenzyme Q reductase) /FL=gb:BC001456.1 gb:BC000170.2 gb:AF050640.1 gb:AF013160.1 gb:NM_004550.1" NM_004550 "NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)" NDUFS2 4720 NM_001166159 /// NM_004550 /// XM_005245208 /// XM_005245209 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation "0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation" 201967_at NM_005777 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005777.1 /DEF=Homo sapiens RNA binding motif protein 6 (RBM6), mRNA. /FEA=mRNA /GEN=RBM6 /PROD=RNA binding motif protein 6 /DB_XREF=gi:5032032 /UG=Hs.173993 RNA binding motif protein 6 /FL=gb:AF042857.1 gb:AF069517.1 gb:U50839.1 gb:AF091264.1 gb:NM_005777.1" NM_005777 RNA binding motif protein 6 RBM6 10180 NM_001167582 /// NM_005777 /// XM_005264784 /// XM_005264785 /// XM_005264786 /// XM_005264787 /// XM_005264788 /// XM_006712916 0006396 // RNA processing // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 201968_s_at NM_002633 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002633.1 /DEF=Homo sapiens phosphoglucomutase 1 (PGM1), mRNA. /FEA=mRNA /GEN=PGM1 /PROD=phosphoglucomutase 1 /DB_XREF=gi:4505764 /UG=Hs.1869 phosphoglucomutase 1 /FL=gb:BC001756.1 gb:M83088.1 gb:NM_002633.1" NM_002633 phosphoglucomutase 1 PGM1 5236 NM_001172818 /// NM_001172819 /// NM_002633 0005975 // carbohydrate metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // not recorded /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0019388 // galactose catabolic process // not recorded /// 0019388 // galactose catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000287 // magnesium ion binding // inferred from electronic annotation /// 0004614 // phosphoglucomutase activity // inferred from direct assay /// 0004614 // phosphoglucomutase activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 201969_at AW003362 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW003362 /FEA=EST /DB_XREF=gi:5850278 /DB_XREF=est:wq65h01.x1 /CLONE=IMAGE:2476177 /UG=Hs.243886 nuclear autoantigenic sperm protein (histone-binding) /FL=gb:M97856.1 gb:NM_002482.1 AW003362 nuclear autoantigenic sperm protein (histone-binding) NASP 4678 NM_001195193 /// NM_002482 /// NM_152298 /// NM_172164 /// XM_005270888 /// XM_005270889 0001824 // blastocyst development // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0043486 // histone exchange // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from sequence or structural similarity 201970_s_at NM_002482 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002482.1 /DEF=Homo sapiens nuclear autoantigenic sperm protein (histone-binding) (NASP), mRNA. /FEA=mRNA /GEN=NASP /PROD=nuclear autoantigenic sperm protein(histone-binding) /DB_XREF=gi:4505332 /UG=Hs.243886 nuclear autoantigenic sperm protein (histone-binding) /FL=gb:M97856.1 gb:NM_002482.1" NM_002482 nuclear autoantigenic sperm protein (histone-binding) NASP 4678 NM_001195193 /// NM_002482 /// NM_152298 /// NM_172164 /// XM_005270888 /// XM_005270889 0001824 // blastocyst development // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0043486 // histone exchange // inferred from sequence or structural similarity 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from sequence or structural similarity 201971_s_at NM_001690 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001690.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 1 (ATP6A1), mRNA. /FEA=mRNA /GEN=ATP6A1 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), alpha polypeptide, 70kD, isoform 1 /DB_XREF=gi:4502304 /UG=Hs.281866 ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 1 /FL=gb:L09235.1 gb:NM_001690.1 gb:AF113129.1" NM_001690 "ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A" ATP6V1A 523 NM_001690 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation" 201972_at AF113129 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF113129.1 /DEF=Homo sapiens vacuolar ATPase isoform VA68 mRNA, complete cds. /FEA=mRNA /PROD=vacuolar ATPase isoform VA68 /DB_XREF=gi:6523820 /UG=Hs.281866 ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha polypeptide, 70kD, isoform 1 /FL=gb:L09235.1 gb:NM_001690.1 gb:AF113129.1" AF113129 "ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A" ATP6V1A 523 NM_001690 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0033572 // transferrin transport // traceable author statement /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation" 201973_s_at AL550875 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL550875 /FEA=EST /DB_XREF=gi:12888273 /DB_XREF=est:AL550875 /CLONE=CS0DI065YO01 (5 prime) /UG=Hs.289112 CGI-43 protein /FL=gb:NM_015622.1 gb:AF151801.1 AL550875 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) /// CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) CCZ1 /// CCZ1B 51622 /// 221960 NM_015622 /// NM_198097 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201974_s_at NM_015622 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015622.1 /DEF=Homo sapiens CGI-43 protein (LOC51622), mRNA. /FEA=mRNA /GEN=LOC51622 /PROD=DKFZP586I1023 protein /DB_XREF=gi:11056021 /UG=Hs.289112 CGI-43 protein /FL=gb:NM_015622.1 gb:AF151801.1" NM_015622 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) CCZ1 51622 NM_015622 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201975_at NM_002956 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002956.1 /DEF=Homo sapiens restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) (RSN), mRNA. /FEA=mRNA /GEN=RSN /PROD=restin (Reed-Steinberg cell-expressedintermediate filament-associated protein) /DB_XREF=gi:4506750 /UG=Hs.31638 restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) /FL=gb:NM_002956.1" NM_002956 CAP-GLY domain containing linker protein 1 CLIP1 6249 NM_001247997 /// NM_002956 /// NM_198240 /// XM_005253593 /// XM_005253594 /// XM_005253595 /// XM_006719551 /// XM_006719552 /// XM_006719553 /// XM_006719554 /// XM_006719555 0000278 // mitotic cell cycle // traceable author statement /// 0001578 // microtubule bundle formation // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from mutant phenotype 0000776 // kinetochore // traceable author statement /// 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from mutant phenotype /// 0005874 // microtubule // inferred from sequence or structural similarity /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0044354 // macropinosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // non-traceable author statement /// 0051010 // microtubule plus-end binding // inferred from direct assay 201976_s_at NM_012334 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012334.1 /DEF=Homo sapiens myosin X (MYO10), mRNA. /FEA=mRNA /GEN=MYO10 /PROD=myosin X /DB_XREF=gi:11037056 /UG=Hs.61638 myosin X /FL=gb:NM_012334.1 gb:AF234532.1 gb:AF247457.2" NM_012334 myosin X MYO10 4651 NM_012334 /// XM_005248306 /// XM_005248307 /// XM_006714475 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0030705 // cytoskeleton-dependent intracellular transport // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051489 // regulation of filopodium assembly // inferred from mutant phenotype 0001726 // ruffle // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0032433 // filopodium tip // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0030507 // spectrin binding // inferred from direct assay /// 0030898 // actin-dependent ATPase activity // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060002 // plus-end directed microfilament motor activity // inferred from sequence or structural similarity" 201977_s_at AI539425 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI539425 /FEA=EST /DB_XREF=gi:4453560 /DB_XREF=est:te46d03.x1 /CLONE=IMAGE:2089733 /UG=Hs.63510 KIAA0141 gene product /FL=gb:D50931.1 gb:NM_014773.1 AI539425 KIAA0141 KIAA0141 9812 NM_001142603 /// NM_014773 /// XM_005268547 /// XM_005268548 /// XM_005268549 /// XM_005268550 /// XM_005268551 /// XM_005268552 /// XM_006714812 /// XR_245861 /// XR_427782 /// XR_427783 0006915 // apoptotic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201978_s_at NM_014773 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014773.1 /DEF=Homo sapiens KIAA0141 gene product (KIAA0141), mRNA. /FEA=mRNA /GEN=KIAA0141 /PROD=KIAA0141 gene product /DB_XREF=gi:7661939 /UG=Hs.63510 KIAA0141 gene product /FL=gb:D50931.1 gb:NM_014773.1" NM_014773 KIAA0141 KIAA0141 9812 NM_001142603 /// NM_014773 /// XM_005268547 /// XM_005268548 /// XM_005268549 /// XM_005268550 /// XM_005268551 /// XM_005268552 /// XM_006714812 /// XR_245861 /// XR_427782 /// XR_427783 0006915 // apoptotic process // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201979_s_at NM_006247 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006247.1 /DEF=Homo sapiens protein phosphatase 5, catalytic subunit (PPP5C), mRNA. /FEA=mRNA /GEN=PPP5C /PROD=protein phosphatase 5, catalytic subunit /DB_XREF=gi:5453957 /UG=Hs.75180 protein phosphatase 5, catalytic subunit /FL=gb:BC001970.1 gb:NM_006247.1" NM_006247 "protein phosphatase 5, catalytic subunit" PPP5C 5536 NM_001204284 /// NM_006247 "0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043278 // response to morphine // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from sequence or structural similarity /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201980_s_at NM_012425 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012425.2 /DEF=Homo sapiens Ras suppressor protein 1 (RSU1), mRNA. /FEA=mRNA /GEN=RSU1 /PROD=ras suppressor protein 1 /DB_XREF=gi:10800408 /UG=Hs.75551 Homo sapiens Ras suppressor protein 1 (RSU1), mRNA /FL=gb:NM_012425.2" NM_012425 Ras suppressor protein 1 RSU1 6251 NM_012425 /// NM_152724 /// XM_005252552 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 201981_at AA148534 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA148534 /FEA=EST /DB_XREF=gi:1721559 /DB_XREF=est:zl06d06.s1 /CLONE=IMAGE:491531 /UG=Hs.75874 pregnancy-associated plasma protein A /FL=gb:U28727.1 gb:NM_002581.1 AA148534 "pregnancy-associated plasma protein A, pappalysin 1" PAPPA 5069 NM_002581 /// XM_006717129 0006508 // proteolysis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201982_s_at NM_002581 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002581.1 /DEF=Homo sapiens pregnancy-associated plasma protein A (PAPPA), mRNA. /FEA=mRNA /GEN=PAPPA /PROD=pregnancy-associated plasma protein A /DB_XREF=gi:4505606 /UG=Hs.75874 pregnancy-associated plasma protein A /FL=gb:U28727.1 gb:NM_002581.1" NM_002581 "pregnancy-associated plasma protein A, pappalysin 1" PAPPA 5069 NM_002581 /// XM_006717129 0006508 // proteolysis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201983_s_at AW157070 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW157070 /FEA=EST /DB_XREF=gi:6228471 /DB_XREF=est:au91e07.x1 /CLONE=IMAGE:2783652 /UG=Hs.77432 epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) /FL=gb:NM_005228.1 AW157070 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 "0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay" 201984_s_at NM_005228 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005228.1 /DEF=Homo sapiens epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) (EGFR), mRNA. /FEA=mRNA /GEN=EGFR /PROD=epidermal growth factor receptor (avianerythroblastic leukemia viral (v-erb-b) oncogene homolog) /DB_XREF=gi:4885198 /UG=Hs.77432 epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) /FL=gb:NM_005228.1" NM_005228 epidermal growth factor receptor EGFR 1956 NM_005228 /// NM_201282 /// NM_201283 /// NM_201284 "0000165 // MAPK cascade // non-traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001503 // ossification // non-traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001942 // hair follicle development // inferred from electronic annotation /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // non-traceable author statement /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007435 // salivary gland morphogenesis // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0010960 // magnesium ion homeostasis // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016101 // diterpenoid metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0019694 // alkanesulfonate metabolic process // inferred from electronic annotation /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033590 // response to cobalamin // inferred from electronic annotation /// 0033594 // response to hydroxyisoflavone // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0043006 // activation of phospholipase A2 activity by calcium-mediated signaling // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043586 // tongue development // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from direct assay /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051205 // protein insertion into membrane // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060571 // morphogenesis of an epithelial fold // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071392 // cellular response to estradiol stimulus // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070435 // Shc-EGFR complex // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005006 // epidermal growth factor-activated receptor activity // non-traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030235 // nitric-oxide synthase regulator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay" 201985_at NM_014846 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014846.1 /DEF=Homo sapiens KIAA0196 gene product (KIAA0196), mRNA. /FEA=mRNA /GEN=KIAA0196 /PROD=KIAA0196 gene product /DB_XREF=gi:7661987 /UG=Hs.8294 KIAA0196 gene product /FL=gb:D83780.1 gb:NM_014846.1" NM_014846 KIAA0196 KIAA0196 9897 NM_014846 /// XM_005251120 0008219 // cell death // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0071203 // WASH complex // inferred from direct assay 201986_at AB011165 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB011165.1 /DEF=Homo sapiens mRNA for KIAA0593 protein, partial cds. /FEA=mRNA /GEN=KIAA0593 /PROD=KIAA0593 protein /DB_XREF=gi:3043709 /UG=Hs.11861 thyroid hormone receptor-associated protein, 240 kDa subunit /FL=gb:AF117754.1 gb:NM_005121.1" AB011165 mediator complex subunit 13 MED13 9969 NM_005121 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 201987_at AI984051 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI984051 /FEA=EST /DB_XREF=gi:5811270 /DB_XREF=est:wt52h03.x1 /CLONE=IMAGE:2511125 /UG=Hs.11861 thyroid hormone receptor-associated protein, 240 kDa subunit /FL=gb:AF117754.1 gb:NM_005121.1" AI984051 mediator complex subunit 13 MED13 9969 NM_005121 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 201988_s_at BF438056 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF438056 /FEA=EST /DB_XREF=gi:11450573 /DB_XREF=est:7q66e01.x1 /CLONE=IMAGE:3703369 /UG=Hs.13313 cAMP responsive element binding protein-like 2 /FL=gb:AF039081.1 gb:NM_001310.1 BF438056 cAMP responsive element binding protein-like 2 CREBL2 1389 NM_001310 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201989_s_at AL529409 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL529409 /FEA=EST /DB_XREF=gi:12792902 /DB_XREF=est:AL529409 /CLONE=CS0DD006YM17 (3 prime) /UG=Hs.13313 cAMP responsive element binding protein-like 2 /FL=gb:AF039081.1 gb:NM_001310.1 AL529409 cAMP responsive element binding protein-like 2 CREBL2 1389 NM_001310 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201990_s_at NM_001310 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001310.1 /DEF=Homo sapiens cAMP responsive element binding protein-like 2 (CREBL2), mRNA. /FEA=mRNA /GEN=CREBL2 /PROD=cAMP responsive element binding protein-like 2 /DB_XREF=gi:4503034 /UG=Hs.13313 cAMP responsive element binding protein-like 2 /FL=gb:AF039081.1 gb:NM_001310.1" NM_001310 cAMP responsive element binding protein-like 2 CREBL2 1389 NM_001310 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201991_s_at BF223224 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF223224 /FEA=EST /DB_XREF=gi:11130401 /DB_XREF=est:7q30g05.x1 /CLONE=IMAGE:3700017 /UG=Hs.149436 kinesin family member 5B /FL=gb:NM_004521.1 BF223224 kinesin family member 5B KIF5B 3799 NM_004521 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 201992_s_at NM_004521 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004521.1 /DEF=Homo sapiens kinesin family member 5B (KIF5B), mRNA. /FEA=mRNA /GEN=KIF5B /PROD=kinesin family member 5B /DB_XREF=gi:4758647 /UG=Hs.149436 kinesin family member 5B /FL=gb:NM_004521.1" NM_004521 kinesin family member 5B KIF5B 3799 NM_004521 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 201993_x_at NM_005463 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005463.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein D-like (HNRPDL), mRNA. /FEA=mRNA /GEN=HNRPDL /PROD=heterogeneous nuclear ribonucleoprotein D-like /DB_XREF=gi:4885422 /UG=Hs.170311 heterogeneous nuclear ribonucleoprotein D-like /FL=gb:AB017019.1 gb:NM_005463.1" NM_005463 heterogeneous nuclear ribonucleoprotein D-like HNRNPDL 9987 NM_001207000 /// NM_005463 /// NM_031372 /// NR_003249 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 201994_at NM_012286 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012286.1 /DEF=Homo sapiens MORF-related gene X (KIAA0026), mRNA. /FEA=mRNA /GEN=KIAA0026 /PROD=MORF-related gene X /DB_XREF=gi:6912447 /UG=Hs.173714 MORF-related gene X /FL=gb:D14812.1 gb:AF100620.1 gb:NM_012286.1 gb:AF167174.1" NM_012286 mortality factor 4 like 2 MORF4L2 9643 NM_001142418 /// NM_001142419 /// NM_001142420 /// NM_001142421 /// NM_001142422 /// NM_001142423 /// NM_001142424 /// NM_001142425 /// NM_001142426 /// NM_001142427 /// NM_001142428 /// NM_001142429 /// NM_001142430 /// NM_001142431 /// NM_001142432 /// NM_012286 "0001558 // regulation of cell growth // non-traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051155 // positive regulation of striated muscle cell differentiation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201995_at NM_000127 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000127.1 /DEF=Homo sapiens exostoses (multiple) 1 (EXT1), mRNA. /FEA=mRNA /GEN=EXT1 /PROD=exostoses (multiple) 1 /DB_XREF=gi:4557570 /UG=Hs.184161 exostoses (multiple) 1 /FL=gb:BC001174.1 gb:NM_000127.1" NM_000127 exostosin glycosyltransferase 1 EXT1 2131 NM_000127 "0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from mutant phenotype /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033692 // cellular polysaccharide biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0072498 // embryonic skeletal joint development // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation "0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from direct assay /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0042328 // heparan sulfate N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from sequence or structural similarity /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // inferred from sequence or structural similarity /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // non-traceable author statement" 201996_s_at AL524033 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL524033 /FEA=EST /DB_XREF=gi:12787526 /DB_XREF=est:AL524033 /CLONE=CS0DC003YL08 (3 prime) /UG=Hs.184245 KIAA0929 protein Msx2 interacting nuclear target (MINT) homolog /FL=gb:NM_015001.1 AL524033 spen family transcriptional repressor SPEN 23013 NM_015001 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201997_s_at NM_015001 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015001.1 /DEF=Homo sapiens KIAA0929 protein Msx2 interacting nuclear target (MINT) homolog (KIAA0929), mRNA. /FEA=mRNA /GEN=KIAA0929 /PROD=KIAA0929 protein Msx2 interacting nuclear target(MINT) homolog /DB_XREF=gi:7657266 /UG=Hs.184245 KIAA0929 protein Msx2 interacting nuclear target (MINT) homolog /FL=gb:NM_015001.1" NM_015001 spen family transcriptional repressor SPEN 23013 NM_015001 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 201998_at AI743792 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI743792 /FEA=EST /DB_XREF=gi:5112080 /DB_XREF=est:wg53h11.x1 /CLONE=IMAGE:2368869 /UG=Hs.2554 sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) /FL=gb:NM_003032.1" AI743792 "ST6 beta-galactosamide alpha-2,6-sialyltranferase 1" ST6GAL1 6480 NM_003032 /// NM_173216 /// NM_173217 /// XM_005247717 /// XM_005247719 /// XM_005247720 /// XM_006713734 0006054 // N-acetylneuraminate metabolic process // inferred from direct assay /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097503 // sialylation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003835 // beta-galactoside alpha-2,6-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation" 201999_s_at NM_006519 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006519.1 /DEF=Homo sapiens t-complex-associated-testis-expressed 1-like 1 (TCTEL1), mRNA. /FEA=mRNA /GEN=TCTEL1 /PROD=t-complex-associated-testis-expressed 1-like 1 /DB_XREF=gi:5730084 /UG=Hs.266940 t-complex-associated-testis-expressed 1-like 1 /FL=gb:U56255.1 gb:D50663.1 gb:NM_006519.1" NM_006519 "dynein, light chain, Tctex-type 1" DYNLT1 6993 NM_001291602 /// NM_001291603 /// NM_006519 /// XM_005267117 0000132 // establishment of mitotic spindle orientation // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0046718 // viral entry into host cell // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0051493 // regulation of cytoskeleton organization // inferred from electronic annotation /// 0075521 // microtubule-dependent intracellular transport of viral material towards nucleus // inferred from electronic annotation /// 0075606 // transport of viral material towards nucleus // inferred from electronic annotation /// 0075733 // intracellular transport of virus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202000_at BC002772 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002772.1 /DEF=Homo sapiens, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14), clone MGC:3686, mRNA, complete cds. /FEA=mRNA /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 6 (14kD, B14) /DB_XREF=gi:12803858 /UG=Hs.274416 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14) /FL=gb:BC002772.1 gb:AF047182.1 gb:NM_002490.1" BC002772 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa" NDUFA6 4700 NM_002490 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202001_s_at NM_002490 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002490.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14) (NDUFA6), mRNA. /FEA=mRNA /GEN=NDUFA6 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 6 (14kD, B14) /DB_XREF=gi:4505358 /UG=Hs.274416 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14) /FL=gb:BC002772.1 gb:AF047182.1 gb:NM_002490.1" NM_002490 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa" NDUFA6 4700 NM_002490 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202002_at AW072302 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW072302 /FEA=EST /DB_XREF=gi:6027300 /DB_XREF=est:wz98h08.x1 /CLONE=IMAGE:2566911 /UG=Hs.32500 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) /FL=gb:BC001918.1 gb:D16294.1 gb:NM_006111.1 AW072302 acetyl-CoA acyltransferase 2 ACAA2 10449 NM_006111 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay /// 1902109 // negative regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202003_s_at NM_006111 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006111.1 /DEF=Homo sapiens acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) (ACAA2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACAA2 /PROD=acetyl-Coenzyme A acyltransferase 2(mitochondrial 3-oxoacyl-Coenzyme A thiolase) /DB_XREF=gi:5174428 /UG=Hs.32500 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) /FL=gb:BC001918.1 gb:D16294.1 gb:NM_006111.1" NM_006111 acetyl-CoA acyltransferase 2 ACAA2 10449 NM_006111 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from direct assay /// 1901029 // negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay /// 1902109 // negative regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202004_x_at NM_003001 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003001.2 /DEF=Homo sapiens succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD (SDHC), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHC /PROD=succinate dehydrogenase complex, subunit Cprecursor /DB_XREF=gi:9257243 /UG=Hs.3577 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD /FL=gb:U57877.1 gb:NM_003001.2" NM_003001 "succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa" SDHC 6391 NM_001035511 /// NM_001035512 /// NM_001035513 /// NM_001278172 /// NM_003001 /// NR_103459 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0045273 // respiratory chain complex II // traceable author statement /// 0045281 // succinate dehydrogenase complex // inferred from electronic annotation "0000104 // succinate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation" 202005_at NM_021978 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021978.1 /DEF=Homo sapiens suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) (ST14), mRNA. /FEA=mRNA /GEN=ST14 /PROD=suppression of tumorigenicity 14 (coloncarcinoma, matriptase, epithin) /DB_XREF=gi:11415039 /UG=Hs.56937 suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) /FL=gb:AF057145.1 gb:NM_021978.1 gb:AB030036.1 gb:AF133086.1 gb:AF118224.2" NM_021978 suppression of tumorigenicity 14 (colon carcinoma) ST14 6768 NM_021978 0006508 // proteolysis // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 202006_at NM_002835 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002835.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 12 (PTPN12), mRNA. /FEA=mRNA /GEN=PTPN12 /PROD=protein tyrosine phosphatase, non-receptor type12 /DB_XREF=gi:4506286 /UG=Hs.62 protein tyrosine phosphatase, non-receptor type 12 /FL=gb:D13380.1 gb:M93425.1 gb:NM_002835.1" NM_002835 "protein tyrosine phosphatase, non-receptor type 12" PTPN12 5782 NM_001131008 /// NM_001131009 /// NM_002835 /// XM_005250518 /// XM_006716073 /// XM_006716074 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0002102 // podosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction 202007_at BF940043 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF940043 /FEA=EST /DB_XREF=gi:12357363 /DB_XREF=est:nac66f12.x1 /CLONE=IMAGE:3439271 /UG=Hs.62041 nidogen (enactin) /FL=gb:M30269.1 gb:NM_002508.1 BF940043 nidogen 1 NID1 4811 NM_002508 /// XM_006711771 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from electronic annotation /// 0071711 // basement membrane organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay /// 0043236 // laminin binding // inferred from direct assay /// 0043237 // laminin-1 binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202008_s_at NM_002508 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002508.1 /DEF=Homo sapiens nidogen (enactin) (NID), mRNA. /FEA=mRNA /GEN=NID /PROD=nidogen (enactin) /DB_XREF=gi:4505394 /UG=Hs.62041 nidogen (enactin) /FL=gb:M30269.1 gb:NM_002508.1" NM_002508 nidogen 1 NID1 4811 NM_002508 /// XM_006711771 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0032836 // glomerular basement membrane development // inferred from electronic annotation /// 0071711 // basement membrane organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay /// 0043236 // laminin binding // inferred from direct assay /// 0043237 // laminin-1 binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202009_at NM_007284 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007284.1 /DEF=Homo sapiens protein tyrosine kinase 9-like (A6-related protein) (PTK9L), mRNA. /FEA=mRNA /GEN=PTK9L /PROD=protein tyrosine kinase 9-like (A6-relatedprotein) /DB_XREF=gi:6005845 /UG=Hs.6780 protein tyrosine kinase 9-like (A6-related protein) /FL=gb:BC000327.1 gb:BC003161.1 gb:NM_007284.1 gb:AL136773.1" NM_007284 twinfilin actin-binding protein 2 TWF2 11344 NM_007284 0010592 // positive regulation of lamellipodium assembly // inferred from mutant phenotype /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0032532 // regulation of microvillus length // inferred by curator /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0042989 // sequestering of actin monomers // inferred from sequence or structural similarity /// 0045773 // positive regulation of axon extension // inferred from mutant phenotype /// 0051016 // barbed-end actin filament capping // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from direct assay /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202010_s_at NM_021188 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021188.1 /DEF=Homo sapiens clones 23667 and 23775 zinc finger protein (LOC57862), mRNA. /FEA=mRNA /GEN=LOC57862 /PROD=clones 23667 and 23775 zinc finger protein /DB_XREF=gi:10863994 /UG=Hs.7137 clones 23667 and 23775 zinc finger protein /FL=gb:NM_021188.1 gb:U90919.1" NM_021188 prostaglandin reductase 2 /// zinc finger protein 410 PTGR2 /// ZNF410 57862 /// 145482 NM_001146154 /// NM_001146155 /// NM_001242924 /// NM_001242926 /// NM_001242927 /// NM_001242928 /// NM_021188 /// NM_152444 /// NR_040251 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0036132 // 13-prostaglandin reductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047522 // 15-oxoprostaglandin 13-oxidase activity // inferred from direct assay 202011_at NM_003257 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003257.1 /DEF=Homo sapiens tight junction protein 1 (zona occludens 1) (TJP1), mRNA. /FEA=mRNA /GEN=TJP1 /PROD=tight junction protein 1 (zona occludens 1) /DB_XREF=gi:4507516 /UG=Hs.74614 tight junction protein 1 (zona occludens 1) /FL=gb:L14837.1 gb:NM_003257.1" NM_003257 tight junction protein 1 TJP1 7082 NM_003257 /// NM_175610 /// XM_005254616 /// XM_005254617 /// XM_005254618 /// XM_005254619 /// XM_005254620 /// XM_005254621 /// XM_006720660 /// XM_006720661 /// XM_006725553 /// XM_006725554 /// XM_006725555 /// XM_006725556 /// XM_006725557 /// XM_006725558 /// XM_006725559 /// XM_006725560 0001825 // blastocyst formation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007043 // cell-cell junction assembly // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0071000 // response to magnetism // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 1901350 // cell-cell signaling involved in cell-cell junction organization // non-traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043296 // apical junction complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0046581 // intercellular canaliculus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 202012_s_at AA196245 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA196245 /FEA=EST /DB_XREF=gi:1791879 /DB_XREF=est:zp92h05.s1 /CLONE=IMAGE:627705 /UG=Hs.75334 exostoses (multiple) 2 /FL=gb:U64511.1 gb:NM_000401.1 AA196245 exostosin glycosyltransferase 2 EXT2 2132 NM_000401 /// NM_001178083 /// NM_207122 "0001503 // ossification // inferred from mutant phenotype /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033692 // cellular polysaccharide biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from direct assay /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0042328 // heparan sulfate N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // non-traceable author statement" 202013_s_at NM_000401 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000401.1 /DEF=Homo sapiens exostoses (multiple) 2 (EXT2), mRNA. /FEA=mRNA /GEN=EXT2 /PROD=exostoses (multiple) 2 /DB_XREF=gi:4557572 /UG=Hs.75334 exostoses (multiple) 2 /FL=gb:U64511.1 gb:NM_000401.1" NM_000401 exostosin glycosyltransferase 2 EXT2 2132 NM_000401 /// NM_001178083 /// NM_207122 "0001503 // ossification // inferred from mutant phenotype /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // inferred from direct assay /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from mutant phenotype /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0033692 // cellular polysaccharide biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031227 // intrinsic component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0008375 // acetylglucosaminyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from direct assay /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0042328 // heparan sulfate N-acetylglucosaminyltransferase activity // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050508 // glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0050509 // N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity // non-traceable author statement" 202014_at NM_014330 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014330.2 /DEF=Homo sapiens growth arrest and DNA-damage-inducible 34 (GADD34), mRNA. /FEA=mRNA /GEN=GADD34 /PROD=growth arrest and DNA-damage-inducible 34 /DB_XREF=gi:9790902 /UG=Hs.76556 growth arrest and DNA-damage-inducible 34 /FL=gb:BC003067.1 gb:U83981.1 gb:NM_014330.2" NM_014330 "protein phosphatase 1, regulatory subunit 15A" PPP1R15A 23645 NM_014330 0006417 // regulation of translation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 202015_x_at NM_006838 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006838.1 /DEF=Homo sapiens methionine aminopeptidase; eIF-2-associated p67 (MNPEP), mRNA. /FEA=mRNA /GEN=MNPEP /PROD=methionine aminopeptidase; eIF-2-associated p67 /DB_XREF=gi:5803091 /UG=Hs.78935 methionine aminopeptidase; eIF-2-associated p67 /FL=gb:NM_006838.1 gb:U29607.1" NM_006838 "0006508 // proteolysis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016485 // protein processing // inferred from direct assay /// 0018206 // peptidyl-methionine modification // inferred from direct assay /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0031365 // N-terminal protein amino acid modification // inferred from direct assay /// 0070084 // protein initiator methionine removal // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004177 // aminopeptidase activity // inferred from direct assay /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // inferred from direct assay /// 0008235 // metalloexopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070006 // metalloaminopeptidase activity // inferred from electronic annotation 202016_at NM_002402 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002402.1 /DEF=Homo sapiens mesoderm specific transcript (mouse) homolog (MEST), mRNA. /FEA=mRNA /GEN=MEST /PROD=mesoderm specific transcript (mouse) homolog /DB_XREF=gi:4505154 /UG=Hs.79284 mesoderm specific transcript (mouse) homolog /FL=gb:BC002413.1 gb:D78611.1 gb:D87367.1 gb:NM_002402.1" NM_002402 mesoderm specific transcript MEST 4232 NM_001253900 /// NM_001253901 /// NM_001253902 /// NM_002402 /// NM_177524 /// NM_177525 0007498 // mesoderm development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010883 // regulation of lipid storage // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202017_at NM_000120 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000120.2 /DEF=Homo sapiens epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), mRNA. /FEA=mRNA /GEN=EPHX1 /PROD=epoxide hydrolase 1, microsomal (xenobiotic) /DB_XREF=gi:4557560 /UG=Hs.89649 epoxide hydrolase 1, microsomal (xenobiotic) /FL=gb:BC003567.1 gb:J03518.1 gb:L25878.1 gb:L25879.1 gb:NM_000120.2" NM_000120 "epoxide hydrolase 1, microsomal (xenobiotic)" EPHX1 2052 NM_000120 /// NM_001136018 /// NM_001291163 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019439 // aromatic compound catabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004301 // epoxide hydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033961 // cis-stilbene-oxide hydrolase activity // inferred from electronic annotation 202018_s_at NM_002343 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002343.1 /DEF=Homo sapiens lactotransferrin (LTF), mRNA. /FEA=mRNA /GEN=LTF /PROD=lactotransferrin /DB_XREF=gi:4505042 /UG=Hs.105938 lactotransferrin /FL=gb:AF332168.1 gb:M93150.1 gb:M83202.1 gb:NM_002343.1" NM_002343 lactotransferrin LTF 4057 NM_001199149 /// NM_002343 "0001503 // ossification // inferred from electronic annotation /// 0001817 // regulation of cytokine production // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002227 // innate immune response in mucosa // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0006959 // humoral immune response // traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0019732 // antifungal humoral response // inferred from direct assay /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0033214 // iron assimilation by chelation and transport // traceable author statement /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051701 // interaction with host // traceable author statement /// 0052572 // response to host immune response // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from direct assay /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090382 // phagosome maturation // traceable author statement /// 1900159 // positive regulation of bone mineralization involved in bone maturation // inferred from sequence or structural similarity /// 1900229 // negative regulation of single-species biofilm formation in or on host organism // inferred from direct assay /// 1902732 // positive regulation of chondrocyte proliferation // inferred from direct assay /// 2000308 // negative regulation of tumor necrosis factor (ligand) superfamily member 11 production // inferred from sequence or structural similarity /// 2001205 // negative regulation of osteoclast development // inferred from sequence or structural similarity" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030141 // secretory granule // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097013 // phagocytic vesicle lumen // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202019_s_at AI935255 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI935255 /FEA=EST /DB_XREF=gi:5674125 /DB_XREF=est:wp16a02.x1 /CLONE=IMAGE:2464970 /UG=Hs.13351 LanC (bacterial lantibiotic synthetase component C)-like 1 /FL=gb:NM_006055.1 AI935255 LanC lantibiotic synthetase component C-like 1 (bacterial) LANCL1 10314 NM_001136574 /// NM_001136575 /// NM_006055 /// XM_005246243 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 202020_s_at NM_006055 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006055.1 /DEF=Homo sapiens LanC (bacterial lantibiotic synthetase component C)-like 1 (LANCL1), mRNA. /FEA=mRNA /GEN=LANCL1 /PROD=lanthionine synthetase C-like protein 1 /DB_XREF=gi:5174444 /UG=Hs.13351 LanC (bacterial lantibiotic synthetase component C)-like 1 /FL=gb:NM_006055.1" NM_006055 LanC lantibiotic synthetase component C-like 1 (bacterial) LANCL1 10314 NM_001136574 /// NM_001136575 /// NM_006055 /// XM_005246243 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay 202021_x_at AF083441 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF083441.1 /DEF=Homo sapiens SUI1 isolog mRNA, complete cds. /FEA=mRNA /PROD=SUI1 isolog /DB_XREF=gi:5813822 /UG=Hs.150580 putative translation initiation factor /FL=gb:BC005118.1 gb:AF100737.1 gb:L26247.1 gb:NM_005801.1 gb:AF083441.1" AF083441 eukaryotic translation initiation factor 1 EIF1 10209 NM_005801 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement "0003743 // translation initiation factor activity // non-traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202022_at NM_005165 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005165.1 /DEF=Homo sapiens aldolase C, fructose-bisphosphate (ALDOC), mRNA. /FEA=mRNA /GEN=ALDOC /PROD=aldolase C, fructose-bisphosphate /DB_XREF=gi:4885062 /UG=Hs.155247 aldolase C, fructose-bisphosphate /FL=gb:BC003613.1 gb:AF054987.1 gb:NM_005165.1" NM_005165 "aldolase C, fructose-bisphosphate" ALDOC 230 NM_005165 /// XM_005257947 /// XM_005257949 "0001666 // response to hypoxia // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051290 // protein heterotetramerization // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred by curator /// 0030424 // axon // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation 202023_at NM_004428 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004428.1 /DEF=Homo sapiens ephrin-A1 (EFNA1), mRNA. /FEA=mRNA /GEN=EFNA1 /PROD=ephrin A1 precursor /DB_XREF=gi:4758245 /UG=Hs.1624 ephrin-A1 /FL=gb:M57730.1 gb:NM_004428.1" NM_004428 ephrin-A1 EFNA1 1942 NM_004428 /// NM_182685 /// XM_005244940 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001525 // angiogenesis // not recorded /// 0003180 // aortic valve morphogenesis // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003199 // endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007411 // axon guidance // not recorded /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0014028 // notochord formation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction 202024_at NM_004317 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004317.1 /DEF=Homo sapiens arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 (ASNA1), mRNA. /FEA=mRNA /GEN=ASNA1 /PROD=arsA (bacterial) arsenite transporter,ATP-binding, homolog 1 /DB_XREF=gi:4757795 /UG=Hs.165439 arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 /FL=gb:BC002651.1 gb:U60276.1 gb:AF047469.1 gb:NM_004317.1" NM_004317 "arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)" ASNA1 439 NM_004317 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015698 // inorganic anion transport // traceable author statement /// 0045048 // protein insertion into ER membrane // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0015105 // arsenite transmembrane transporter activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202025_x_at NM_001607 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001607.2 /DEF=Homo sapiens acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) (ACAA1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACAA1 /PROD=acetyl-Coenzyme A acyltransferase 1 /DB_XREF=gi:6598316 /UG=Hs.166160 acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) /FL=gb:BC000635.1 gb:NM_001607.2" NM_001607 acetyl-CoA acyltransferase 1 ACAA1 30 NM_001130410 /// NM_001607 /// NR_024024 /// XM_006713122 /// XM_006713123 0000038 // very long-chain fatty acid metabolic process // inferred from mutant phenotype /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from mutant phenotype /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016401 // palmitoyl-CoA oxidase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation" 202026_at NM_003002 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003002.1 /DEF=Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHD /PROD=succinate dehydrogenase complex, subunit Dprecursor /DB_XREF=gi:4506864 /UG=Hs.168289 succinate dehydrogenase complex, subunit D, integral membrane protein /FL=gb:BC005263.1 gb:AB006202.1 gb:NM_003002.1" NM_003002 "succinate dehydrogenase complex, subunit D, integral membrane protein" SDHD 6392 NM_001276503 /// NM_001276504 /// NM_001276506 /// NM_003002 /// NR_077060 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005740 // mitochondrial envelope // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from sequence or structural similarity 202027_at NM_012264 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012264.1 /DEF=Homo sapiens chromosome 22 open reading frame 5 (C22ORF5), mRNA. /FEA=mRNA /GEN=C22ORF5 /PROD=chromosome 22 open reading frame 5 /DB_XREF=gi:7110634 /UG=Hs.182626 chromosome 22 open reading frame 5 /FL=gb:NM_012264.1" NM_012264 transmembrane protein 184B TMEM184B 25829 NM_001195071 /// NM_001195072 /// NM_012264 /// XM_005261509 /// XM_005261510 /// XM_005261511 /// XM_005261512 /// XM_005261513 /// XM_005261514 /// XM_006724227 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202028_s_at BC000603 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BC000603.1 /DEF=Homo sapiens, ribosomal protein L38, clone MGC:1637, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L38 /DB_XREF=gi:12653644 /UG=Hs.2017 ribosomal protein L38 /FL=gb:BC000603.1 gb:NM_000999.1" BC000603 ribosomal protein L38 RPL38 6169 NM_000999 /// NM_001035258 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034463 // 90S preribosome assembly // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048318 // axial mesoderm development // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0033291 // eukaryotic 80S initiation complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 202029_x_at NM_000999 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000999.1 /DEF=Homo sapiens ribosomal protein L38 (RPL38), mRNA. /FEA=mRNA /GEN=RPL38 /PROD=ribosomal protein L38 /DB_XREF=gi:4506644 /UG=Hs.2017 ribosomal protein L38 /FL=gb:BC000603.1 gb:NM_000999.1" NM_000999 ribosomal protein L38 RPL38 6169 NM_000999 /// NM_001035258 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0034463 // 90S preribosome assembly // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048318 // axial mesoderm development // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0033291 // eukaryotic 80S initiation complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement 202030_at NM_005881 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005881.1 /DEF=Homo sapiens branched chain alpha-ketoacid dehydrogenase kinase (BCKDK), mRNA. /FEA=mRNA /GEN=BCKDK /PROD=branched chain alpha-ketoacid dehydrogenasekinase /DB_XREF=gi:5031608 /UG=Hs.20644 branched chain alpha-ketoacid dehydrogenase kinase /FL=gb:AF026548.1 gb:NM_005881.1" NM_005881 branched chain ketoacid dehydrogenase kinase BCKDK 10295 NM_001122957 /// NM_001271926 /// NM_005881 0006468 // protein phosphorylation // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // non-traceable author statement /// 0009083 // branched-chain amino acid catabolic process // inferred from sequence or structural similarity /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // inferred from sequence or structural similarity /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047323 // [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity // inferred from electronic annotation" 202031_s_at NM_015610 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015610.1 /DEF=Homo sapiens DKFZP434J154 protein (DKFZP434J154), mRNA. /FEA=mRNA /GEN=DKFZP434J154 /PROD=DKFZP434J154 protein /DB_XREF=gi:7661579 /UG=Hs.226372 DKFZP434J154 protein /FL=gb:BC004116.1 gb:AL080155.1 gb:NM_015610.1" NM_015610 "WD repeat domain, phosphoinositide interacting 2" WIPI2 26100 NM_001033518 /// NM_001033519 /// NM_001033520 /// NM_001278299 /// NM_015610 /// NM_016003 /// XM_006715685 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000421 // autophagic vacuole membrane // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay "0005515 // protein binding // inferred from physical interaction /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay" 202032_s_at NM_006122 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006122.1 /DEF=Homo sapiens mannosidase, alpha, class 2A, member 2 (MAN2A2), mRNA. /FEA=mRNA /GEN=MAN2A2 /PROD=mannosidase, alpha, class 2A, member 2 /DB_XREF=gi:5540099 /UG=Hs.295605 mannosidase, alpha, class 2A, member 2 /FL=gb:NM_006122.1 gb:L28821.1" NM_006122 "mannosidase, alpha, class 2A, member 2" MAN2A2 4122 NM_006122 /// XM_005254910 /// XM_005254911 /// XM_006720507 /// XR_243208 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0004572 // mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 202033_s_at BG402105 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG402105 /FEA=EST /DB_XREF=gi:13295553 /DB_XREF=est:602465641F1 /CLONE=IMAGE:4593682 /UG=Hs.50421 KIAA0203 gene product /FL=gb:D86958.1 gb:NM_014781.1 BG402105 RB1-inducible coiled-coil 1 RB1CC1 9821 NM_001083617 /// NM_014781 /// XM_006716491 /// XM_006716492 /// XM_006716493 "0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 202034_x_at NM_014781 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014781.1 /DEF=Homo sapiens KIAA0203 gene product (KIAA0203), mRNA. /FEA=mRNA /GEN=KIAA0203 /PROD=KIAA0203 gene product /DB_XREF=gi:7661991 /UG=Hs.50421 KIAA0203 gene product /FL=gb:D86958.1 gb:NM_014781.1" NM_014781 RB1-inducible coiled-coil 1 RB1CC1 9821 NM_001083617 /// NM_014781 /// XM_006716491 /// XM_006716492 /// XM_006716493 "0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0000407 // pre-autophagosomal structure // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 202035_s_at AI332407 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI332407 /FEA=EST /DB_XREF=gi:4068966 /DB_XREF=est:qq15g12.x1 /CLONE=IMAGE:1932646 /UG=Hs.7306 secreted frizzled-related protein 1 /FL=gb:AF001900.1 gb:AF017987.1 gb:AF056087.1 gb:NM_003012.2 AI332407 secreted frizzled-related protein 1 SFRP1 6422 NM_003012 "0001649 // osteoblast differentiation // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009790 // embryo development // /// 0009950 // dorsal/ventral axis specification // inferred from direct assay /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014034 // neural crest cell fate commitment // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0044345 // stromal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0045578 // negative regulation of B cell differentiation // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0045880 // positive regulation of smoothened signaling pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071380 // cellular response to prostaglandin E stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0071773 // cellular response to BMP stimulus // inferred from expression pattern /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090175 // regulation of establishment of planar polarity // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred from electronic annotation /// 0090246 // convergent extension involved in somitogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000041 // negative regulation of planar cell polarity pathway involved in axis elongation // inferred from electronic annotation /// 2000052 // positive regulation of non-canonical Wnt signaling pathway // inferred from direct assay /// 2000054 // negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000080 // negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation // inferred from direct assay /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042995 // cell projection // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 202036_s_at AF017987 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF017987.1 /DEF=Homo sapiens secreted apoptosis related protein 2 (SARP2) mRNA, complete cds. /FEA=mRNA /GEN=SARP2 /PROD=secreted apoptosis related protein 2 /DB_XREF=gi:2415416 /UG=Hs.7306 secreted frizzled-related protein 1 /FL=gb:AF001900.1 gb:AF017987.1 gb:AF056087.1 gb:NM_003012.2" AF017987 secreted frizzled-related protein 1 SFRP1 6422 NM_003012 "0001649 // osteoblast differentiation // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009790 // embryo development // /// 0009950 // dorsal/ventral axis specification // inferred from direct assay /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014034 // neural crest cell fate commitment // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0044345 // stromal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0045578 // negative regulation of B cell differentiation // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0045880 // positive regulation of smoothened signaling pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071380 // cellular response to prostaglandin E stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0071773 // cellular response to BMP stimulus // inferred from expression pattern /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090175 // regulation of establishment of planar polarity // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred from electronic annotation /// 0090246 // convergent extension involved in somitogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000041 // negative regulation of planar cell polarity pathway involved in axis elongation // inferred from electronic annotation /// 2000052 // positive regulation of non-canonical Wnt signaling pathway // inferred from direct assay /// 2000054 // negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000080 // negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation // inferred from direct assay /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042995 // cell projection // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 202037_s_at NM_003012 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003012.2 /DEF=Homo sapiens secreted frizzled-related protein 1 (SFRP1), mRNA. /FEA=mRNA /GEN=SFRP1 /PROD=secreted frizzled-related protein 1 /DB_XREF=gi:8400731 /UG=Hs.7306 secreted frizzled-related protein 1 /FL=gb:AF001900.1 gb:AF017987.1 gb:AF056087.1 gb:NM_003012.2" NM_003012 secreted frizzled-related protein 1 SFRP1 6422 NM_003012 "0001649 // osteoblast differentiation // inferred from expression pattern /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0001954 // positive regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006508 // proteolysis // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009790 // embryo development // /// 0009950 // dorsal/ventral axis specification // inferred from direct assay /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010719 // negative regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014034 // neural crest cell fate commitment // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0022601 // menstrual cycle phase // inferred from expression pattern /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from direct assay /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043508 // negative regulation of JUN kinase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0044345 // stromal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0045578 // negative regulation of B cell differentiation // inferred from mutant phenotype /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0045880 // positive regulation of smoothened signaling pathway // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046546 // development of primary male sexual characteristics // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0046851 // negative regulation of bone remodeling // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051894 // positive regulation of focal adhesion assembly // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060218 // hematopoietic stem cell differentiation // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060766 // negative regulation of androgen receptor signaling pathway // inferred from direct assay /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071380 // cellular response to prostaglandin E stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0071481 // cellular response to X-ray // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0071773 // cellular response to BMP stimulus // inferred from expression pattern /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090175 // regulation of establishment of planar polarity // inferred from electronic annotation /// 0090179 // planar cell polarity pathway involved in neural tube closure // inferred from electronic annotation /// 0090244 // Wnt signaling pathway involved in somitogenesis // inferred from electronic annotation /// 0090246 // convergent extension involved in somitogenesis // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000041 // negative regulation of planar cell polarity pathway involved in axis elongation // inferred from electronic annotation /// 2000052 // positive regulation of non-canonical Wnt signaling pathway // inferred from direct assay /// 2000054 // negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification // inferred from direct assay /// 2000080 // negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation // inferred from direct assay /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from direct assay /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042995 // cell projection // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 202038_at NM_004788 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004788.1 /DEF=Homo sapiens ubiquitination factor E4A (homologous to yeast UFD2) (UBE4A), mRNA. /FEA=mRNA /GEN=UBE4A /PROD=ubiquitination factor E4A (homologous to yeastUFD2) /DB_XREF=gi:4759287 /UG=Hs.75275 ubiquitination factor E4A (homologous to yeast UFD2) /FL=gb:D50916.1 gb:NM_004788.1" NM_004788 ubiquitination factor E4A UBE4A 9354 NM_001204077 /// NM_004788 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 202039_at NM_004740 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004740.1 /DEF=Homo sapiens TGFB1-induced anti-apoptotic factor 1 (TIAF1), mRNA. /FEA=mRNA /GEN=TIAF1 /PROD=TGFB1-induced anti-apoptotic factor 1 /DB_XREF=gi:4759231 /UG=Hs.75822 TGFB1-induced anti-apoptotic factor 1 /FL=gb:D86970.1 gb:AF105277.1 gb:NM_004740.1" NM_004740 myosin XVIIIA /// TGFB1-induced anti-apoptotic factor 1 MYO18A /// TIAF1 9220 /// 399687 NM_004740 /// NM_078471 /// NM_203318 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007249 // I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0048194 // Golgi vesicle budding // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from mutant phenotype /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0042641 // actomyosin // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0043531 // ADP binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay 202040_s_at NM_005056 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005056.1 /DEF=Homo sapiens retinoblastoma-binding protein 2 (RBBP2), mRNA. /FEA=mRNA /GEN=RBBP2 /PROD=retinoblastoma-binding protein 2 /DB_XREF=gi:4826967 /UG=Hs.76272 retinoblastoma-binding protein 2 /FL=gb:NM_005056.1" NM_005056 lysine (K)-specific demethylase 5A KDM5A 5927 NM_001042603 /// NM_005056 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 202041_s_at NM_004214 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004214.3 /DEF=Homo sapiens fibroblast growth factor (acidic) intracellular binding protein (FIBP), mRNA. /FEA=mRNA /GEN=FIBP /PROD=fibroblast growth factor (acidic) intracellularbinding protein /DB_XREF=gi:7262377 /UG=Hs.7768 fibroblast growth factor (acidic) intracellular binding protein /FL=gb:AF171944.1 gb:AF171945.1 gb:AF171946.1 gb:AF010187.2 gb:NM_004214.3" NM_004214 fibroblast growth factor (acidic) intracellular binding protein FIBP 9158 NM_004214 /// NM_198897 /// XM_005274391 /// XM_005274392 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0017134 // fibroblast growth factor binding // inferred from physical interaction 202042_at NM_002109 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002109.2 /DEF=Homo sapiens histidyl-tRNA synthetase (HARS), mRNA. /FEA=mRNA /GEN=HARS /PROD=histidyl tRNA synthetase /DB_XREF=gi:6996013 /UG=Hs.77798 histidyl-tRNA synthetase /FL=gb:NM_002109.2" NM_002109 histidyl-tRNA synthetase /// uncharacterized LOC101928623 HARS /// LOC101928623 3035 /// 101928623 NM_001258040 /// NM_001258041 /// NM_001258042 /// NM_001289092 /// NM_001289093 /// NM_001289094 /// NM_002109 /// XM_005268428 /// XR_242729 /// XR_242730 /// XR_247486 /// XR_252702 /// XR_252703 /// XR_424088 /// XR_424089 /// XR_424090 /// XR_428675 /// XR_432546 0006412 // translation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006427 // histidyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004821 // histidine-tRNA ligase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202043_s_at NM_004595 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004595.1 /DEF=Homo sapiens spermine synthase (SMS), mRNA. /FEA=mRNA /GEN=SMS /PROD=spermine synthase /DB_XREF=gi:4759151 /UG=Hs.89718 spermine synthase /FL=gb:AD001528.1 gb:NM_004595.1" NM_004595 spermine synthase SMS 6611 NM_001258423 /// NM_004595 /// XM_005274582 /// XM_005274583 0006555 // methionine metabolic process // traceable author statement /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004766 // spermidine synthase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016768 // spermine synthase activity // inferred from electronic annotation 202044_at AU159484 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU159484 /FEA=EST /DB_XREF=gi:11021005 /DB_XREF=est:AU159484 /CLONE=THYRO1001796 /UG=Hs.102548 glucocorticoid receptor DNA binding factor 1 /FL=gb:M73077.1 gb:NM_004491.1 AU159484 Rho GTPase activating protein 35 ARHGAP35 2909 NM_004491 /// NM_024342 "0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 202045_s_at AI670100 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI670100 /FEA=EST /DB_XREF=gi:4834874 /DB_XREF=est:wc11g10.x1 /CLONE=IMAGE:2314914 /UG=Hs.102548 glucocorticoid receptor DNA binding factor 1 /FL=gb:M73077.1 gb:NM_004491.1 AI670100 Rho GTPase activating protein 35 ARHGAP35 2909 NM_004491 /// NM_024342 "0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 202046_s_at NM_004491 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004491.1 /DEF=Homo sapiens glucocorticoid receptor DNA binding factor 1 (GRLF1), mRNA. /FEA=mRNA /GEN=GRLF1 /PROD=glucocorticoid receptor DNA binding factor 1 /DB_XREF=gi:4758481 /UG=Hs.102548 glucocorticoid receptor DNA binding factor 1 /FL=gb:M73077.1 gb:NM_004491.1" NM_004491 Rho GTPase activating protein 35 ARHGAP35 2909 NM_004491 /// NM_024342 "0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 202047_s_at AI458128 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI458128 /FEA=EST /DB_XREF=gi:4312134 /DB_XREF=est:tj64g03.x1 /CLONE=IMAGE:2146324 /UG=Hs.107374 chromobox homolog 6 /FL=gb:NM_014292.1 AI458128 chromobox homolog 6 CBX6 23466 NM_014292 /// XM_005261412 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation" 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202048_s_at NM_014292 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014292.1 /DEF=Homo sapiens chromobox homolog 6 (CBX6), mRNA. /FEA=mRNA /GEN=CBX6 /PROD=chromobox homolog 6 /DB_XREF=gi:10140848 /UG=Hs.107374 chromobox homolog 6 /FL=gb:NM_014292.1" NM_014292 chromobox homolog 6 CBX6 23466 NM_014292 /// XM_005261412 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation" 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202049_s_at AA521508 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA521508 /FEA=EST /DB_XREF=gi:2262051 /DB_XREF=est:aa74h06.s1 /CLONE=IMAGE:826715 /UG=Hs.150390 zinc finger protein 262 /FL=gb:AB007885.1 gb:NM_005095.1 AA521508 "zinc finger, MYM-type 4" ZMYM4 9202 NM_005095 /// XM_005271328 /// XM_005271330 /// XM_005271331 /// XM_006711034 /// XM_006711035 /// XR_246305 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202050_s_at AI650586 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI650586 /FEA=EST /DB_XREF=gi:4734565 /DB_XREF=est:wa92g09.x1 /CLONE=IMAGE:2303680 /UG=Hs.150390 zinc finger protein 262 /FL=gb:AB007885.1 gb:NM_005095.1 AI650586 "zinc finger, MYM-type 4" ZMYM4 9202 NM_005095 /// XM_005271328 /// XM_005271330 /// XM_005271331 /// XM_006711034 /// XM_006711035 /// XR_246305 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202051_s_at NM_005095 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005095.1 /DEF=Homo sapiens zinc finger protein 262 (ZNF262), mRNA. /FEA=mRNA /GEN=ZNF262 /PROD=zinc finger protein 262 /DB_XREF=gi:4827068 /UG=Hs.150390 zinc finger protein 262 /FL=gb:AB007885.1 gb:NM_005095.1" NM_005095 "zinc finger, MYM-type 4" ZMYM4 9202 NM_005095 /// XM_005271328 /// XM_005271330 /// XM_005271331 /// XM_006711034 /// XM_006711035 /// XR_246305 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0007275 // multicellular organismal development // traceable author statement /// 0022604 // regulation of cell morphogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202052_s_at NM_015577 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015577.1 /DEF=Homo sapiens novel retinal pigment epithelial gene (NORPEG), mRNA. /FEA=mRNA /GEN=NORPEG /PROD=DKFZP564G013 protein /DB_XREF=gi:13470085 /UG=Hs.15165 novel retinal pigment epithelial gene /FL=gb:NM_015577.1 gb:AF155135.1" NM_015577 retinoic acid induced 14 RAI14 26064 NM_001145520 /// NM_001145521 /// NM_001145522 /// NM_001145523 /// NM_001145525 /// NM_015577 /// XM_006714469 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 202053_s_at L47162 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L47162.1 /DEF=Human fatty aldehyde dehydrogenase (FALDH) mRNA, complete cds. /FEA=mRNA /GEN=FALDH /PROD=fatty aldehyde dehydrogenase /DB_XREF=gi:1082035 /UG=Hs.159608 aldehyde dehydrogenase 3 family, member A2 /FL=gb:L47162.1 gb:U46689.1 gb:NM_000382.1" L47162 "aldehyde dehydrogenase 3 family, member A2" ALDH3A2 224 NM_000382 /// NM_001031806 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0006081 // cellular aldehyde metabolic process // non-traceable author statement /// 0006714 // sesquiterpenoid metabolic process // inferred from direct assay /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0007422 // peripheral nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0033306 // phytol metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from mutant phenotype /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046577 // long-chain-alcohol oxidase activity // inferred from direct assay /// 0050061 // long-chain-aldehyde dehydrogenase activity // inferred from direct assay /// 0052814 // medium-chain-aldehyde dehydrogenase activity // inferred from direct assay" 202054_s_at NM_000382 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000382.1 /DEF=Homo sapiens aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), mRNA. /FEA=mRNA /GEN=ALDH3A2 /PROD=aldehyde dehydrogenase 3A2 /DB_XREF=gi:4557302 /UG=Hs.159608 aldehyde dehydrogenase 3 family, member A2 /FL=gb:L47162.1 gb:U46689.1 gb:NM_000382.1" NM_000382 "aldehyde dehydrogenase 3 family, member A2" ALDH3A2 224 NM_000382 /// NM_001031806 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0006081 // cellular aldehyde metabolic process // non-traceable author statement /// 0006714 // sesquiterpenoid metabolic process // inferred from direct assay /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0007422 // peripheral nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0008544 // epidermis development // inferred from mutant phenotype /// 0033306 // phytol metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from mutant phenotype /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046577 // long-chain-alcohol oxidase activity // inferred from direct assay /// 0050061 // long-chain-aldehyde dehydrogenase activity // inferred from direct assay /// 0052814 // medium-chain-aldehyde dehydrogenase activity // inferred from direct assay" 202055_at AA652173 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA652173 /FEA=EST /DB_XREF=gi:2583825 /DB_XREF=est:ns51f05.s1 /CLONE=IMAGE:1187169 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1 AA652173 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202056_at AW051311 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW051311 /FEA=EST /DB_XREF=gi:5913581 /DB_XREF=est:wy89b01.x1 /CLONE=IMAGE:2555689 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1 AW051311 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202057_at BC002374 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BC002374.1 /DEF=Homo sapiens, karyopherin alpha 1 (importin alpha 5), clone MGC:8554, mRNA, complete cds. /FEA=mRNA /PROD=karyopherin alpha 1 (importin alpha 5) /DB_XREF=gi:12803140 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1" BC002374 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202058_s_at BC002374 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002374.1 /DEF=Homo sapiens, karyopherin alpha 1 (importin alpha 5), clone MGC:8554, mRNA, complete cds. /FEA=mRNA /PROD=karyopherin alpha 1 (importin alpha 5) /DB_XREF=gi:12803140 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1" BC002374 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202059_s_at NM_002264 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002264.1 /DEF=Homo sapiens karyopherin alpha 1 (importin alpha 5) (KPNA1), mRNA. /FEA=mRNA /GEN=KPNA1 /PROD=karyopherin alpha 1 /DB_XREF=gi:4504894 /UG=Hs.169149 karyopherin alpha 1 (importin alpha 5) /FL=gb:BC002374.1 gb:BC003009.1 gb:NM_002264.1" NM_002264 karyopherin alpha 1 (importin alpha 5) KPNA1 3836 NM_002264 /// NR_026698 /// XM_005247437 /// XM_005247439 0000018 // regulation of DNA recombination // traceable author statement /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019058 // viral life cycle // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0075733 // intracellular transport of virus // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005643 // nuclear pore // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from sequence or structural similarity 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 202060_at NM_014633 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014633.1 /DEF=Homo sapiens KIAA0155 gene product (KIAA0155), mRNA. /FEA=mRNA /GEN=KIAA0155 /PROD=KIAA0155 gene product /DB_XREF=gi:7661949 /UG=Hs.173288 KIAA0155 gene product /FL=gb:NM_014633.1 gb:D63875.1" NM_014633 "CTR9, Paf1/RNA polymerase II complex component" CTR9 9646 NM_014633 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001711 // endodermal cell fate commitment // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from mutant phenotype /// 0070102 // interleukin-6-mediated signaling pathway // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0080182 // histone H3-K4 trimethylation // inferred from mutant phenotype /// 2001162 // positive regulation of histone H3-K79 methylation // inferred from mutant phenotype" 0005634 // nucleus // inferred from electronic annotation /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0035327 // transcriptionally active chromatin // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0042169 // SH2 domain binding // inferred from electronic annotation 202061_s_at AI927770 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI927770 /FEA=EST /DB_XREF=gi:5663734 /DB_XREF=est:wo08h07.x1 /CLONE=IMAGE:2454781 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1" AI927770 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202062_s_at NM_005065 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005065.1 /DEF=Homo sapiens sel-1 (suppressor of lin-12, C.elegans)-like (SEL1L), mRNA. /FEA=mRNA /GEN=SEL1L /PROD=sel-1 (suppressor of lin-12, C.elegans)-like /DB_XREF=gi:4826995 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1" NM_005065 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202063_s_at AB020335 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB020335.1 /DEF=Homo sapiens Pancreas-specific TSA305 mRNA , complete cds. /FEA=mRNA /GEN=TSA305 /DB_XREF=gi:6518494 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1" AB020335 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202064_s_at AF052059 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF052059.1 /DEF=Homo sapiens SEL1L (SEL1L) mRNA, complete cds. /FEA=mRNA /GEN=SEL1L /PROD=SEL1L /DB_XREF=gi:6851088 /UG=Hs.181300 sel-1 (suppressor of lin-12, C.elegans)-like /FL=gb:NM_005065.1 gb:AB020335.1 gb:AF052059.1 gb:U11037.1" AF052059 sel-1 suppressor of lin-12-like (C. elegans) SEL1L 6400 NM_001244984 /// NM_005065 /// XM_005267988 /// XM_005267989 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202065_s_at BG033593 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG033593 /FEA=EST /DB_XREF=gi:12426042 /DB_XREF=est:602301717F1 /CLONE=IMAGE:4403212 /UG=Hs.183648 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 /FL=gb:NM_003626.1 gb:U22816.1" BG033593 "protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1" PPFIA1 8500 NM_003626 /// NM_177423 /// NR_045286 /// XM_006718715 /// XM_006718716 /// XM_006718717 /// XM_006718718 /// XM_006718719 /// XM_006718720 /// XM_006718721 /// XM_006718722 /// XM_006718723 /// XM_006718724 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202066_at AA195259 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA195259 /FEA=EST /DB_XREF=gi:1784959 /DB_XREF=est:zr36g01.s1 /CLONE=IMAGE:665520 /UG=Hs.183648 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 /FL=gb:NM_003626.1 gb:U22816.1" AA195259 "protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1" PPFIA1 8500 NM_003626 /// NM_177423 /// NR_045286 /// XM_006718715 /// XM_006718716 /// XM_006718717 /// XM_006718718 /// XM_006718719 /// XM_006718720 /// XM_006718721 /// XM_006718722 /// XM_006718723 /// XM_006718724 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202067_s_at AI861942 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI861942 /FEA=EST /DB_XREF=gi:5526049 /DB_XREF=est:td18b10.x1 /CLONE=IMAGE:2075995 /UG=Hs.213289 low density lipoprotein receptor (familial hypercholesterolemia) /FL=gb:NM_000527.2 AI861942 low density lipoprotein receptor LDLR 3949 NM_000527 /// NM_001195798 /// NM_001195799 /// NM_001195800 /// NM_001195802 /// NM_001195803 /// XR_244074 "0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070508 // cholesterol import // inferred from sequence or structural similarity" 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay 202068_s_at NM_000527 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000527.2 /DEF=Homo sapiens low density lipoprotein receptor (familial hypercholesterolemia) (LDLR), mRNA. /FEA=mRNA /GEN=LDLR /PROD=low density lipoprotein receptor precursor /DB_XREF=gi:8051613 /UG=Hs.213289 low density lipoprotein receptor (familial hypercholesterolemia) /FL=gb:NM_000527.2" NM_000527 low density lipoprotein receptor LDLR 3949 NM_000527 /// NM_001195798 /// NM_001195799 /// NM_001195800 /// NM_001195802 /// NM_001195803 /// XR_244074 "0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0010899 // regulation of phosphatidylcholine catabolic process // inferred from sequence or structural similarity /// 0015914 // phospholipid transport // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0030299 // intestinal cholesterol absorption // inferred from mutant phenotype /// 0030301 // cholesterol transport // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0070508 // cholesterol import // inferred from sequence or structural similarity" 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from electronic annotation /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay 202069_s_at AI826060 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI826060 /FEA=EST /DB_XREF=gi:5446731 /DB_XREF=est:wk28a12.x1 /CLONE=IMAGE:2413630 /UG=Hs.250616 isocitrate dehydrogenase 3 (NAD+) alpha /FL=gb:NM_005530.1 gb:U07681.1 AI826060 isocitrate dehydrogenase 3 (NAD+) alpha IDH3A 3419 NM_005530 /// XM_005254334 /// XM_005254336 /// XM_005254337 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001552 // ovarian follicle atresia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042552 // myelination // non-traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 202070_s_at NM_005530 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005530.1 /DEF=Homo sapiens isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A), mRNA. /FEA=mRNA /GEN=IDH3A /PROD=isocitrate dehydrogenase 3 (NAD+) alpha /DB_XREF=gi:5031776 /UG=Hs.250616 isocitrate dehydrogenase 3 (NAD+) alpha /FL=gb:NM_005530.1 gb:U07681.1" NM_005530 isocitrate dehydrogenase 3 (NAD+) alpha IDH3A 3419 NM_005530 /// XM_005254334 /// XM_005254336 /// XM_005254337 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001552 // ovarian follicle atresia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042552 // myelination // non-traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 202071_at NM_002999 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002999.1 /DEF=Homo sapiens syndecan 4 (amphiglycan, ryudocan) (SDC4), mRNA. /FEA=mRNA /GEN=SDC4 /PROD=syndecan 4 (amphiglycan, ryudocan) /DB_XREF=gi:4506860 /UG=Hs.252189 syndecan 4 (amphiglycan, ryudocan) /FL=gb:NM_002999.1" NM_002999 syndecan 4 SDC4 6385 NM_002999 "0001523 // retinoid metabolic process // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0070053 // thrombospondin receptor activity // inferred from mutant phenotype 202072_at NM_001533 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001533.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein L (HNRPL), mRNA. /FEA=mRNA /GEN=HNRPL /PROD=heterogeneous nuclear ribonucleoprotein L /DB_XREF=gi:4557644 /UG=Hs.2730 heterogeneous nuclear ribonucleoprotein L /FL=gb:AB044547.1 gb:NM_001533.1" NM_001533 heterogeneous nuclear ribonucleoprotein L HNRNPL 3191 NM_001005335 /// NM_001533 /// XR_243927 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202073_at AV757675 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV757675 /FEA=EST /DB_XREF=gi:10915523 /DB_XREF=est:AV757675 /CLONE=BMFAVB12 /UG=Hs.278898 tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Huntingtin interacting protein L; transcrption factor IIIA-interacting protein /FL=gb:NM_021980.1 AV757675 optineurin OPTN 10133 NM_001008211 /// NM_001008212 /// NM_001008213 /// NM_021980 /// XM_005252336 /// XM_005252337 /// XM_005252338 0000042 // protein targeting to Golgi // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001920 // negative regulation of receptor recycling // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016236 // macroautophagy // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0050829 // defense response to Gram-negative bacterium // inferred from mutant phenotype /// 0090161 // Golgi ribbon formation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 202074_s_at NM_021980 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021980.1 /DEF=Homo sapiens tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Huntingtin interacting protein L; transcrption factor IIIA-interacting protein (FIP2), mRNA. /FEA=mRNA /GEN=FIP2 /PROD=tumor necrosis factor alpha-inducible cellularprotein containing leucine zipper domains; Huntingtininteracting protein L; transcrption factorIIIA-interacting protein /DB_XREF=gi:11415041 /UG=Hs.278898 tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains; Huntingtin interacting protein L; transcrption factor IIIA-interacting protein /FL=gb:NM_021980.1" NM_021980 optineurin OPTN 10133 NM_001008211 /// NM_001008212 /// NM_001008213 /// NM_021980 /// XM_005252336 /// XM_005252337 /// XM_005252338 0000042 // protein targeting to Golgi // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001920 // negative regulation of receptor recycling // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016236 // macroautophagy // inferred from direct assay /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0050829 // defense response to Gram-negative bacterium // inferred from mutant phenotype /// 0090161 // Golgi ribbon formation // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay 202075_s_at NM_006227 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006227.1 /DEF=Homo sapiens phospholipid transfer protein (PLTP), mRNA. /FEA=mRNA /GEN=PLTP /PROD=phospholipid transfer protein /DB_XREF=gi:5453913 /UG=Hs.283007 phospholipid transfer protein /FL=gb:L26232.1 gb:NM_006227.1" NM_006227 phospholipid transfer protein PLTP 5360 NM_001242920 /// NM_001242921 /// NM_006227 /// NM_182676 /// XM_005260439 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0010189 // vitamin E biosynthetic process // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation 202076_at NM_001166 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001166.2 /DEF=Homo sapiens baculoviral IAP repeat-containing 2 (BIRC2), mRNA. /FEA=mRNA /GEN=BIRC2 /PROD=baculoviral IAP repeat-containing protein 2 /DB_XREF=gi:10880127 /UG=Hs.289107 baculoviral IAP repeat-containing 2 /FL=gb:NM_001166.2 gb:U37547.1 gb:L49431.1 gb:U45879.1" NM_001166 baculoviral IAP repeat containing 2 BIRC2 329 NM_001166 /// NM_001256163 /// NM_001256166 "0000209 // protein polyubiquitination // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0034121 // regulation of toll-like receptor signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038061 // NIK/NF-kappaB signaling // traceable author statement /// 0039535 // regulation of RIG-I signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045088 // regulation of innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // traceable author statement /// 0050727 // regulation of inflammatory response // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay /// 0060544 // regulation of necroptotic process // inferred from mutant phenotype /// 0070266 // necroptotic process // inferred from electronic annotation /// 0070424 // regulation of nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 1902523 // positive regulation of protein K63-linked ubiquitination // inferred from direct assay /// 1902524 // positive regulation of protein K48-linked ubiquitination // inferred from direct assay /// 1902527 // positive regulation of protein monoubiquitination // inferred from direct assay /// 2000116 // regulation of cysteine-type endopeptidase activity // traceable author statement" 0001741 // XY body // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 202077_at NM_005003 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005003.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1, alphabeta subcomplex, 1 (8kD, SDAP) (NDUFAB1), mRNA. /FEA=mRNA /GEN=NDUFAB1 /PROD=NADH dehydrogenase (ubiquinone) 1, alphabetasubcomplex, 1 (8kD, SDAP) /DB_XREF=gi:4826851 /UG=Hs.5556 NADH dehydrogenase (ubiquinone) 1, alphabeta subcomplex, 1 (8kD, SDAP) /FL=gb:AF087660.1 gb:NM_005003.1" NM_005003 "NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa" NDUFAB1 4706 NM_005003 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // non-traceable author statement /// 0009249 // protein lipoylation // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from sequence or structural similarity /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // non-traceable author statement /// 0070469 // respiratory chain // inferred from electronic annotation 0000036 // ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process // non-traceable author statement /// 0005504 // fatty acid binding // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // non-traceable author statement /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202078_at NM_003653 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003653.1 /DEF=Homo sapiens COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3 (COPS3), mRNA. /FEA=mRNA /GEN=COPS3 /PROD=COP9 (constitutive photomorphogenic,Arabidopsis, homolog) subunit 3 /DB_XREF=gi:4502974 /UG=Hs.6076 COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3 /FL=gb:BC001891.1 gb:AF031647.1 gb:NM_003653.1 gb:AF098109.1" NM_003653 COP9 signalosome subunit 3 COPS3 8533 NM_001199125 /// NM_003653 /// XM_005256837 /// XM_005256838 /// XM_005256839 /// XM_005256840 /// XM_005256841 /// XM_005256842 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0009416 // response to light stimulus // traceable author statement /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202079_s_at AI633774 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI633774 /FEA=EST /DB_XREF=gi:4685104 /DB_XREF=est:tt28d06.x1 /CLONE=IMAGE:2242091 /UG=Hs.6705 KIAA1042 protein /FL=gb:AB028965.1 gb:NM_014965.1 AI633774 "trafficking protein, kinesin binding 1" TRAK1 22906 NM_001042646 /// NM_001265608 /// NM_001265609 /// NM_001265610 /// NM_014965 /// XM_005264956 /// XM_005264957 /// XM_005264958 /// XM_005264959 /// XM_005264960 /// XM_005264962 /// XM_005264963 /// XM_005264964 /// XM_006713028 /// XM_006713029 /// XM_006713030 /// XM_006713031 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 202080_s_at NM_014965 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014965.1 /DEF=Homo sapiens KIAA1042 protein (KIAA1042), mRNA. /FEA=mRNA /GEN=KIAA1042 /PROD=KIAA1042 protein /DB_XREF=gi:7662457 /UG=Hs.6705 KIAA1042 protein /FL=gb:AB028965.1 gb:NM_014965.1" NM_014965 "trafficking protein, kinesin binding 1" TRAK1 22906 NM_001042646 /// NM_001265608 /// NM_001265609 /// NM_001265610 /// NM_014965 /// XM_005264956 /// XM_005264957 /// XM_005264958 /// XM_005264959 /// XM_005264960 /// XM_005264962 /// XM_005264963 /// XM_005264964 /// XM_006713028 /// XM_006713029 /// XM_006713030 /// XM_006713031 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein O-linked glycosylation // inferred from sequence or structural similarity /// 0006605 // protein targeting // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 202081_at NM_004907 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004907.1 /DEF=Homo sapiens immediate early protein (ETR101), mRNA. /FEA=mRNA /GEN=ETR101 /PROD=immediate early protein /DB_XREF=gi:4758313 /UG=Hs.737 immediate early protein /FL=gb:BC003625.1 gb:M62831.1 gb:NM_004907.1" NM_004907 immediate early response 2 IER2 9592 NM_004907 0005737 // cytoplasm // inferred from electronic annotation 202082_s_at AV748469 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV748469 /FEA=EST /DB_XREF=gi:10906317 /DB_XREF=est:AV748469 /CLONE=NPCAXA07 /UG=Hs.75232 SEC14 (S. cerevisiae)-like 1 /FL=gb:D67029.1 gb:NM_003003.1 AV748469 SEC14-like 1 (S. cerevisiae) SEC14L1 6397 NM_001039573 /// NM_001143998 /// NM_001143999 /// NM_001144001 /// NM_001204408 /// NM_001204410 /// NM_003003 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 202083_s_at AI017770 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI017770 /FEA=EST /DB_XREF=gi:3232106 /DB_XREF=est:ov32b12.x1 /CLONE=IMAGE:1639007 /UG=Hs.75232 SEC14 (S. cerevisiae)-like 1 /FL=gb:D67029.1 gb:NM_003003.1 AI017770 SEC14-like 1 (S. cerevisiae) SEC14L1 6397 NM_001039573 /// NM_001143998 /// NM_001143999 /// NM_001144001 /// NM_001204408 /// NM_001204410 /// NM_003003 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 202084_s_at NM_003003 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003003.1 /DEF=Homo sapiens SEC14 (S. cerevisiae)-like 1 (SEC14L1), mRNA. /FEA=mRNA /GEN=SEC14L1 /PROD=SEC14 (S. cerevisiae)-like 1 /DB_XREF=gi:4506866 /UG=Hs.75232 SEC14 (S. cerevisiae)-like 1 /FL=gb:D67029.1 gb:NM_003003.1" NM_003003 SEC14-like 1 (S. cerevisiae) SEC14L1 6397 NM_001039573 /// NM_001143998 /// NM_001143999 /// NM_001144001 /// NM_001204408 /// NM_001204410 /// NM_003003 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 202085_at NM_004817 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004817.1 /DEF=Homo sapiens tight junction protein 2 (zona occludens 2) (TJP2), mRNA. /FEA=mRNA /GEN=TJP2 /PROD=tight junction protein 2 (zona occludens 2) /DB_XREF=gi:4759341 /UG=Hs.75608 tight junction protein 2 (zona occludens 2) /FL=gb:NM_004817.1 gb:L27476.1" NM_004817 tight junction protein 2 TJP2 9414 NM_001170414 /// NM_001170415 /// NM_001170416 /// NM_001170630 /// NM_004817 /// NM_201629 /// XM_005252311 /// XM_005252312 /// XM_005252313 /// XM_005252314 /// XM_005252315 /// XM_006717324 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0046939 // nucleotide phosphorylation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005912 // adherens junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation 202086_at NM_002462 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002462.1 /DEF=Homo sapiens myxovirus (influenza) resistance 1, homolog of murine (interferon-inducible protein p78) (MX1), mRNA. /FEA=mRNA /GEN=MX1 /PROD=myxovirus (influenza) resistance 1, homolog ofmurine (interferon-inducible protein p78) /DB_XREF=gi:4505290 /UG=Hs.76391 myxovirus (influenza) resistance 1, homolog of murine (interferon-inducible protein p78) /FL=gb:M30817.1 gb:M33882.1 gb:NM_002462.1" NM_002462 "myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)" MX1 4599 NM_001144925 /// NM_001178046 /// NM_001282920 /// NM_002462 /// XM_005260978 /// XM_005260979 /// XM_005260980 /// XM_005260981 /// XM_005260982 /// XM_006724005 0002376 // immune system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0009615 // response to virus // inferred from mutant phenotype /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0034340 // response to type I interferon // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 202087_s_at NM_001912 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001912.1 /DEF=Homo sapiens cathepsin L (CTSL), mRNA. /FEA=mRNA /GEN=CTSL /PROD=cathepsin L /DB_XREF=gi:4503154 /UG=Hs.78056 cathepsin L /FL=gb:NM_001912.1" NM_001912 cathepsin L CTSL 1514 NM_001257971 /// NM_001257972 /// NM_001257973 /// NM_001912 /// NM_145918 /// XM_005251716 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0006508 // proteolysis // inferred from direct assay /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0071888 // macrophage apoptotic process // non-traceable author statement /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction 202088_at AI635449 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI635449 /FEA=EST /DB_XREF=gi:4686779 /DB_XREF=est:ts65a01.x1 /CLONE=IMAGE:2233416 /UG=Hs.79136 LIV-1 protein, estrogen regulated /FL=gb:U41060.2 gb:NM_012319.2" AI635449 "solute carrier family 39 (zinc transporter), member 6" SLC39A6 25800 NM_001099406 /// NM_012319 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0006882 // cellular zinc ion homeostasis // inferred from direct assay /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from mutant phenotype /// 0071578 // zinc ion transmembrane import // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from direct assay 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 202089_s_at NM_012319 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012319.2 /DEF=Homo sapiens LIV-1 protein, estrogen regulated (LIV-1), mRNA. /FEA=mRNA /GEN=LIV-1 /PROD=LIV-1 protein, estrogen regulated /DB_XREF=gi:12751474 /UG=Hs.79136 LIV-1 protein, estrogen regulated /FL=gb:U41060.2 gb:NM_012319.2" NM_012319 "solute carrier family 39 (zinc transporter), member 6" SLC39A6 25800 NM_001099406 /// NM_012319 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0006882 // cellular zinc ion homeostasis // inferred from direct assay /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071577 // zinc ion transmembrane transport // inferred from mutant phenotype /// 0071578 // zinc ion transmembrane import // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from direct assay 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 202090_s_at NM_006830 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006830.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase (6.4kD) subunit (UQCR), mRNA. /FEA=mRNA /GEN=UQCR /PROD=ubiquinol-cytochrome c reductase (6.4kD)subunit /DB_XREF=gi:5803216 /UG=Hs.8372 ubiquinol-cytochrome c reductase (6.4kD) subunit /FL=gb:D55636.1 gb:NM_006830.1" NM_006830 "ubiquinol-cytochrome c reductase, complex III subunit XI" UQCR11 10975 NM_006830 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement 202091_at BC003087 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BC003087.1 /DEF=Homo sapiens, binder of Arl Two, clone MGC:1121, mRNA, complete cds. /FEA=mRNA /PROD=binder of Arl Two /DB_XREF=gi:13111840 /UG=Hs.9552 binder of Arl Two /FL=gb:BC003087.1 gb:AF126062.1 gb:NM_012106.1" BC003087 202092_s_at BF244411 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF244411 /FEA=EST /DB_XREF=gi:11158342 /DB_XREF=est:601862994F1 /CLONE=IMAGE:4080550 /UG=Hs.9552 binder of Arl Two /FL=gb:BC003087.1 gb:AF126062.1 gb:NM_012106.1 BF244411 ADP-ribosylation factor-like 2 binding protein ARL2BP 23568 NM_012106 0007165 // signal transduction // traceable author statement /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051457 // maintenance of protein location in nucleus // inferred from mutant phenotype /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005083 // small GTPase regulator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202093_s_at NM_019088 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019088.1 /DEF=Homo sapiens hypothetical protein F23149_1 (F23149_1), mRNA. /FEA=mRNA /GEN=F23149_1 /PROD=hypothetical protein F23149_1 /DB_XREF=gi:9506582 /UG=Hs.152894 hypothetical protein F23149_1 /FL=gb:BC000017.1 gb:NM_019088.1" NM_019088 "Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)" PAF1 54623 NM_001256826 /// NM_019088 /// NR_046384 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001711 // endodermal cell fate commitment // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0010390 // histone monoubiquitination // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0031442 // positive regulation of mRNA 3'-end processing // inferred from mutant phenotype /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from direct assay /// 0045638 // negative regulation of myeloid cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016593 // Cdc73/Paf1 complex // inferred from direct assay 0000993 // RNA polymerase II core binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202094_at AA648913 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA648913 /FEA=EST /DB_XREF=gi:2575342 /DB_XREF=est:ns41a09.s1 /CLONE=IMAGE:1186168 /UG=Hs.1578 baculoviral IAP repeat-containing 5 (survivin) /FL=gb:NM_001168.1 gb:AF077350.1 AA648913 baculoviral IAP repeat containing 5 BIRC5 332 NM_001012270 /// NM_001012271 /// NM_001168 /// XR_243654 "0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from mutant phenotype /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype /// 0051303 // establishment of chromosome localization // inferred from mutant phenotype" "0000228 // nuclear chromosome // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031021 // interphase microtubule organizing center // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction" 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0008536 // Ran GTPase binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from direct assay /// 0050897 // cobalt ion binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from physical interaction 202095_s_at NM_001168 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001168.1 /DEF=Homo sapiens baculoviral IAP repeat-containing 5 (survivin) (BIRC5), mRNA. /FEA=mRNA /GEN=BIRC5 /PROD=baculoviral IAP repeat-containing protein 5 /DB_XREF=gi:4502144 /UG=Hs.1578 baculoviral IAP repeat-containing 5 (survivin) /FL=gb:NM_001168.1 gb:AF077350.1" NM_001168 baculoviral IAP repeat containing 5 BIRC5 332 NM_001012270 /// NM_001012271 /// NM_001168 /// XR_243654 "0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from mutant phenotype /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype /// 0051303 // establishment of chromosome localization // inferred from mutant phenotype" "0000228 // nuclear chromosome // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031021 // interphase microtubule organizing center // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction" 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008017 // microtubule binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // non-traceable author statement /// 0008536 // Ran GTPase binding // inferred from physical interaction /// 0015631 // tubulin binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048037 // cofactor binding // inferred from direct assay /// 0050897 // cobalt ion binding // non-traceable author statement /// 0051087 // chaperone binding // inferred from physical interaction 202096_s_at NM_000714 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000714.2 /DEF=Homo sapiens benzodiazapine receptor (peripheral) (BZRP), nuclear gene encoding mitochondrial protein, transcript variant PBR, mRNA. /FEA=mRNA /GEN=BZRP /PROD=peripheral benzodiazapine receptor /DB_XREF=gi:6382068 /UG=Hs.202 benzodiazapine receptor (peripheral) /FL=gb:BC001110.1 gb:M36035.1 gb:NM_000714.2" NM_000714 translocator protein (18kDa) TSPO 706 NM_000714 /// NM_001256530 /// NM_001256531 /// NM_007311 /// NR_046308 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006820 // anion transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008347 // glial cell migration // inferred from electronic annotation /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010266 // response to vitamin B1 // inferred from electronic annotation /// 0010940 // positive regulation of necrotic cell death // inferred from electronic annotation /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0032374 // regulation of cholesterol transport // traceable author statement /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from electronic annotation /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050810 // regulation of steroid biosynthetic process // inferred from electronic annotation /// 0051901 // positive regulation of mitochondrial depolarization // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060242 // contact inhibition // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071294 // cellular response to zinc ion // inferred from electronic annotation /// 0071476 // cellular hypotonic response // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005497 // androgen binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008503 // benzodiazepine receptor activity // inferred from electronic annotation /// 0015485 // cholesterol binding // traceable author statement 202097_at NM_005124 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005124.1 /DEF=Homo sapiens nucleoporin 153kD (NUP153), mRNA. /FEA=mRNA /GEN=NUP153 /PROD=nucleoporin 153kD /DB_XREF=gi:4826871 /UG=Hs.211608 nucleoporin 153kD /FL=gb:NM_005124.1" NM_005124 nucleoporin 153kDa NUP153 9972 NM_001278209 /// NM_001278210 /// NM_005124 /// XM_005249507 /// XM_006715290 /// XM_006715291 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046718 // viral entry into host cell // inferred from electronic annotation /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0075732 // viral penetration into host nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0043495 // protein anchor // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 202098_s_at NM_001535 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001535.1 /DEF=Homo sapiens HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 (HRMT1L1), mRNA. /FEA=mRNA /GEN=HRMT1L1 /PROD=HMT1 (hnRNP methyltransferase, S.cerevisiae)-like 1 /DB_XREF=gi:4504494 /UG=Hs.235887 HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1 /FL=gb:U80213.1 gb:NM_001535.1" NM_001535 protein arginine methyltransferase 2 PRMT2 3275 NM_001242864 /// NM_001242865 /// NM_001242866 /// NM_001286676 /// NM_001286677 /// NM_001286678 /// NM_001535 /// NM_206962 /// XM_005261111 /// XM_006723998 /// XM_006723999 /// XM_006724000 "0006479 // protein methylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016571 // histone methylation // inferred from direct assay /// 0016571 // histone methylation // inferred from sequence or structural similarity /// 0019919 // peptidyl-arginine methylation, to asymmetrical-dimethyl arginine // not recorded /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034969 // histone arginine methylation // not recorded /// 0035246 // peptidyl-arginine N-methylation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048588 // developmental cell growth // inferred from sequence or structural similarity /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0035189 // Rb-E2F complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008276 // protein methyltransferase activity // inferred from electronic annotation /// 0008469 // histone-arginine N-methyltransferase activity // not recorded /// 0008469 // histone-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016274 // protein-arginine N-methyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0033142 // progesterone receptor binding // inferred from physical interaction /// 0035242 // protein-arginine omega-N asymmetric methyltransferase activity // not recorded /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 202099_s_at H42875 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:H42875 /FEA=EST /DB_XREF=gi:918927 /DB_XREF=est:yo68b01.s1 /CLONE=IMAGE:183049 /UG=Hs.2491 DiGeorge syndrome critical region gene 2 /FL=gb:D79985.1 gb:NM_005137.1 H42875 DiGeorge syndrome critical region gene 2 DGCR2 9993 NM_001173533 /// NM_001173534 /// NM_001184781 /// NM_005137 /// NR_033674 0007155 // cell adhesion // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 202100_at BG169673 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG169673 /FEA=EST /DB_XREF=gi:12676376 /DB_XREF=est:602324650F1 /CLONE=IMAGE:4427484 /UG=Hs.250811 v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) /FL=gb:M35416.1 gb:NM_002881.1 BG169673 v-ral simian leukemia viral oncogene homolog B RALB 5899 NM_002881 /// XM_005263724 /// XM_005263727 /// XM_005263728 /// XM_005263729 0000910 // cytokinesis // inferred from direct assay /// 0001928 // regulation of exocyst assembly // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0060178 // regulation of exocyst localization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay 202101_s_at NM_002881 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002881.1 /DEF=Homo sapiens v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) (RALB), mRNA. /FEA=mRNA /GEN=RALB /PROD=v-ral simian leukemia viral oncogene homolog B /DB_XREF=gi:4506404 /UG=Hs.250811 v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) /FL=gb:M35416.1 gb:NM_002881.1" NM_002881 v-ral simian leukemia viral oncogene homolog B RALB 5899 NM_002881 /// XM_005263724 /// XM_005263727 /// XM_005263728 /// XM_005263729 0000910 // cytokinesis // inferred from direct assay /// 0001928 // regulation of exocyst assembly // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0060178 // regulation of exocyst localization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay 202102_s_at BF718610 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF718610 /FEA=EST /DB_XREF=gi:12019523 /DB_XREF=est:KEST81 /CLONE=S90413.NIH-116-R.ab1 /UG=Hs.278675 bromodomain-containing 4 /FL=gb:NM_014299.1 BF718610 bromodomain containing 4 BRD4 23476 NM_014299 /// NM_058243 "0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043983 // histone H4-K12 acetylation // inferred from electronic annotation /// 0044154 // histone H3-K14 acetylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 1901407 // regulation of phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 202103_at AI991631 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI991631 /FEA=EST /DB_XREF=gi:5838623 /DB_XREF=est:wr12h09.x1 /CLONE=IMAGE:2481377 /UG=Hs.278675 bromodomain-containing 4 /FL=gb:NM_014299.1 AI991631 bromodomain containing 4 BRD4 23476 NM_014299 /// NM_058243 "0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043983 // histone H4-K12 acetylation // inferred from electronic annotation /// 0044154 // histone H3-K14 acetylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050727 // regulation of inflammatory response // inferred from direct assay /// 1901407 // regulation of phosphorylation of RNA polymerase II C-terminal domain // inferred from direct assay /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0002039 // p53 binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 202104_s_at NM_003119 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003119.1 /DEF=Homo sapiens spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) (SPG7), mRNA. /FEA=mRNA /GEN=SPG7 /PROD=paraplegin /DB_XREF=gi:4507172 /UG=Hs.296847 spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) /FL=gb:NM_003119.1" NM_003119 uncharacterized LOC101930112 /// spastic paraplegia 7 (pure and complicated autosomal recessive) LOC101930112 /// SPG7 6687 /// 101930112 NM_003119 /// NM_199367 /// XM_005256321 /// XM_006721264 /// XM_006721265 /// XM_006721266 /// XR_253599 0006508 // proteolysis // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 202105_at NM_001551 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001551.1 /DEF=Homo sapiens immunoglobulin (CD79A) binding protein 1 (IGBP1), mRNA. /FEA=mRNA /GEN=IGBP1 /PROD=immunoglobulin-binding protein 1 /DB_XREF=gi:4557662 /UG=Hs.3631 immunoglobulin (CD79A) binding protein 1 /FL=gb:BC004137.1 gb:NM_001551.1" NM_001551 immunoglobulin (CD79A) binding protein 1 IGBP1 3476 NM_001551 /// XR_430521 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035306 // positive regulation of dephosphorylation // inferred from electronic annotation /// 0035308 // negative regulation of protein dephosphorylation // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060632 // regulation of microtubule-based movement // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from direct assay /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation 202106_at NM_005895 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005895.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 3 (GOLGA3), mRNA. /FEA=mRNA /GEN=GOLGA3 /PROD=golgi autoantigen, golgin subfamily a, 3 /DB_XREF=gi:5174440 /UG=Hs.4953 golgi autoantigen, golgin subfamily a, 3 /FL=gb:D63997.1 gb:NM_005895.1" NM_005895 golgin A3 GOLGA3 2802 NM_001172557 /// NM_005895 /// XM_005266162 /// XM_005266164 /// XM_005266165 /// XM_005266167 /// XM_006719736 /// XM_006719737 /// XM_006719738 /// XM_006719739 /// XM_006719740 0006891 // intra-Golgi vesicle-mediated transport // non-traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0090498 // extrinsic component of Golgi membrane // inferred from direct assay 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202107_s_at NM_004526 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004526.1 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin) (MCM2), mRNA. /FEA=mRNA /GEN=MCM2 /PROD=minichromosome maintenance deficient (S.cerevisiae) 2 (mitotin) /DB_XREF=gi:4758705 /UG=Hs.57101 minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin) /FL=gb:D83987.1 gb:NM_004526.1" NM_004526 minichromosome maintenance complex component 2 MCM2 4171 NM_004526 /// NR_073375 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from mutant phenotype /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003688 // DNA replication origin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202108_at NM_000285 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000285.1 /DEF=Homo sapiens peptidase D (PEPD), mRNA. /FEA=mRNA /GEN=PEPD /PROD=Xaa-Pro dipeptidase /DB_XREF=gi:4557834 /UG=Hs.73947 peptidase D /FL=gb:BC004305.1 gb:J04605.1 gb:NM_000285.1" NM_000285 peptidase D PEPD 5184 NM_000285 /// NM_001166056 /// NM_001166057 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016805 // dipeptidase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202109_at NM_012402 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012402.1 /DEF=Homo sapiens partner of RAC1 (arfaptin 2) (POR1), mRNA. /FEA=mRNA /GEN=POR1 /PROD=partner of RAC1 (arfaptin 2) /DB_XREF=gi:6912601 /UG=Hs.75139 partner of RAC1 (arfaptin 2) /FL=gb:BC000392.1 gb:U52522.1 gb:NM_012402.1" NM_012402 ADP-ribosylation factor interacting protein 2 ARFIP2 23647 NM_001242854 /// NM_001242855 /// NM_001242856 /// NM_012402 /// XM_005252840 0006928 // cellular component movement // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030032 // lamellipodium assembly // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from mutant phenotype /// 0031529 // ruffle organization // traceable author statement 0001726 // ruffle // inferred from mutant phenotype /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // traceable author statement /// 0048365 // Rac GTPase binding // traceable author statement 202110_at NM_001866 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001866.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIb (COX7B), mRNA. /FEA=mRNA /GEN=COX7B /PROD=cytochrome c oxidase subunit VIIb /DB_XREF=gi:4502990 /UG=Hs.75752 cytochrome c oxidase subunit VIIb /FL=gb:NM_001866.1" NM_001866 cytochrome c oxidase subunit VIIb COX7B 1349 NM_001866 0007417 // central nervous system development // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 202111_at NM_003040 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003040.1 /DEF=Homo sapiens solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (SLC4A2), mRNA. /FEA=mRNA /GEN=SLC4A2 /PROD=solute carrier family 4, anion exchanger, member2 (erythrocyte membrane protein band 3-like 1) /DB_XREF=gi:4507022 /UG=Hs.79410 solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) /FL=gb:U62531.1 gb:NM_003040.1" NM_003040 "solute carrier family 4 (anion exchanger), member 2" SLC4A2 6522 NM_001199692 /// NM_001199693 /// NM_001199694 /// NM_003040 /// XM_006716094 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // traceable author statement /// 0015108 // chloride transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation 202112_at NM_000552 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000552.2 /DEF=Homo sapiens von Willebrand factor (VWF), mRNA. /FEA=mRNA /GEN=VWF /PROD=von Willebrand factor precursor /DB_XREF=gi:9257255 /UG=Hs.110802 von Willebrand factor /FL=gb:NM_000552.2" NM_000552 von Willebrand factor VWF 7450 NM_000552 "0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007596 // blood coagulation // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from mutant phenotype /// 0009611 // response to wounding // traceable author statement /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031589 // cell-substrate adhesion // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay" 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031091 // platelet alpha granule // non-traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from direct assay /// 0002020 // protease binding // inferred from direct assay /// 0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0019865 // immunoglobulin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from direct assay 202113_s_at AF043453 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF043453.1 /DEF=Homo sapiens sorting nexin 2 (SNX2) mRNA, complete cds. /FEA=mRNA /GEN=SNX2 /PROD=sorting nexin 2 /DB_XREF=gi:2827433 /UG=Hs.11183 sorting nexin 2 /FL=gb:BC003382.1 gb:AF043453.1 gb:AF065482.1 gb:NM_003100.1" AF043453 sorting nexin 2 SNX2 6643 NM_001278199 /// NM_003100 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // not recorded 202114_at NM_003100 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003100.1 /DEF=Homo sapiens sorting nexin 2 (SNX2), mRNA. /FEA=mRNA /GEN=SNX2 /PROD=sorting nexin 2 /DB_XREF=gi:4507140 /UG=Hs.11183 sorting nexin 2 /FL=gb:BC003382.1 gb:AF043453.1 gb:AF065482.1 gb:NM_003100.1" NM_003100 sorting nexin 2 SNX2 6643 NM_001278199 /// NM_003100 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // not recorded /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // not recorded /// 0030904 // retromer complex // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // not recorded 202115_s_at NM_015658 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015658.1 /DEF=Homo sapiens DKFZP564C186 protein (DKFZP564C186), mRNA. /FEA=mRNA /GEN=DKFZP564C186 /PROD=DKFZP564C186 protein /DB_XREF=gi:7661605 /UG=Hs.134200 DKFZP564C186 protein /FL=gb:BC003555.1 gb:NM_015658.1" NM_015658 nucleolar complex associated 2 homolog (S. cerevisiae) NOC2L 26155 NM_015658 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002903 // negative regulation of B cell apoptotic process // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay /// 0032066 // nucleolus to nucleoplasm transport // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035067 // negative regulation of histone acetylation // inferred from direct assay /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031491 // nucleosome binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from direct assay 202116_at NM_006268 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006268.2 /DEF=Homo sapiens requiem, apoptosis response zinc finger gene (REQ), mRNA. /FEA=mRNA /GEN=REQ /PROD=requiem /DB_XREF=gi:10862706 /UG=Hs.13495 requiem, apoptosis response zinc finger gene /FL=gb:NM_006268.2 gb:U94585.1 gb:AF001433.1" NM_006268 "D4, zinc and double PHD fingers family 2" DPF2 5977 NM_006268 /// XM_005274149 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202117_at BG468434 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG468434 /FEA=EST /DB_XREF=gi:13400704 /DB_XREF=est:602510404F1 /CLONE=IMAGE:4644528 /UG=Hs.138860 Rho GTPase activating protein 1 /FL=gb:NM_004308.1 BG468434 Rho GTPase activating protein 1 ARHGAP1 392 NM_004308 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // non-traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 202118_s_at AA541758 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA541758 /FEA=EST /DB_XREF=gi:2288192 /DB_XREF=est:ni87d05.s1 /CLONE=IMAGE:983817 /UG=Hs.14158 copine III /FL=gb:AB014536.1 gb:NM_003909.1 gb:AF077226.2 AA541758 copine III CPNE3 8895 NM_003909 /// XM_005251093 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202119_s_at NM_003909 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003909.1 /DEF=Homo sapiens copine III (CPNE3), mRNA. /FEA=mRNA /GEN=CPNE3 /PROD=copine III /DB_XREF=gi:4503014 /UG=Hs.14158 copine III /FL=gb:AB014536.1 gb:NM_003909.1 gb:AF077226.2" NM_003909 copine III CPNE3 8895 NM_003909 /// XM_005251093 0006468 // protein phosphorylation // inferred from direct assay /// 0006629 // lipid metabolic process // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202120_x_at NM_004069 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004069.2 /DEF=Homo sapiens adaptor-related protein complex 2, sigma 1 subunit (AP2S1), transcript variant AP17, mRNA. /FEA=mRNA /GEN=AP2S1 /PROD=adaptor-related protein complex 2, sigma 1subunit, isoform AP17 /DB_XREF=gi:11038644 /UG=Hs.119591 adaptor-related protein complex 2, sigma 1 subunit /FL=gb:NM_004069.2" NM_004069 "adaptor-related protein complex 2, sigma 1 subunit" AP2S1 1175 NM_004069 /// NM_021575 /// XM_005258499 /// XM_005258500 /// XM_006723004 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030100 // regulation of endocytosis // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048268 // clathrin coat assembly // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement 0005215 // transporter activity // non-traceable author statement /// 0008565 // protein transporter activity // non-traceable author statement 202121_s_at NM_014453 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014453.1 /DEF=Homo sapiens putative breast adenocarcinoma marker (32kD) (BC-2), mRNA. /FEA=mRNA /GEN=BC-2 /PROD=putative breast adenocarcinoma marker (32kD) /DB_XREF=gi:7656921 /UG=Hs.12107 putative breast adenocarcinoma marker (32kD) /FL=gb:AF042384.1 gb:NM_014453.1" NM_014453 charged multivesicular body protein 2A CHMP2A 27243 NM_014453 /// NM_198426 /// XM_005258746 /// XM_005258747 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0050792 // regulation of viral process // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 1902188 // positive regulation of viral release from host cell // inferred from mutant phenotype 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202122_s_at NM_005817 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005817.1 /DEF=Homo sapiens cargo selection protein (mannose 6 phosphate receptor binding protein) (TIP47), mRNA. /FEA=mRNA /GEN=TIP47 /PROD=cargo selection protein (mannose 6 phosphatereceptor binding protein) /DB_XREF=gi:5032182 /UG=Hs.140452 cargo selection protein (mannose 6 phosphate receptor binding protein) /FL=gb:AF057140.1 gb:AF051314.1 gb:AF051315.1 gb:AF055574.1 gb:NM_005817.1" NM_005817 perilipin 3 PLIN3 10226 NM_001164189 /// NM_001164194 /// NM_005817 0006810 // transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202123_s_at NM_005157 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005157.2 /DEF=Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1), transcript variant a, mRNA. /FEA=mRNA /GEN=ABL1 /PROD=v-abl Abelson murine leukemia viral oncogenehomolog 1 isoform a /DB_XREF=gi:6382056 /UG=Hs.146355 v-abl Abelson murine leukemia viral oncogene homolog 1 /FL=gb:M14752.1 gb:NM_005157.2" NM_005157 "ABL proto-oncogene 1, non-receptor tyrosine kinase" ABL1 25 NM_005157 /// NM_007313 "0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // traceable author statement /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030100 // regulation of endocytosis // traceable author statement /// 0030155 // regulation of cell adhesion // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051353 // positive regulation of oxidoreductase activity // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 2000145 // regulation of cell motility // traceable author statement /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2001020 // regulation of response to DNA damage stimulus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003785 // actin monomer binding // traceable author statement /// 0004515 // nicotinate-nucleotide adenylyltransferase activity // traceable author statement /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from physical interaction" 202124_s_at AV705253 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AV705253 /FEA=EST /DB_XREF=gi:10722559 /DB_XREF=est:AV705253 /CLONE=ADBBQF03 /UG=Hs.154248 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 /FL=gb:AB038951.1 gb:NM_015049.1" AV705253 "trafficking protein, kinesin binding 2" TRAK2 66008 NM_015049 /// XM_006712714 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0050811 // GABA receptor binding // non-traceable author statement 202125_s_at NM_015049 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015049.1 /DEF=Homo sapiens amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 (ALS2CR3), mRNA. /FEA=mRNA /GEN=ALS2CR3 /PROD=amyotrophic lateral sclerosis 2 (juvenile)chromosome region, candidate 3 /DB_XREF=gi:13027379 /UG=Hs.154248 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3 /FL=gb:AB038951.1 gb:NM_015049.1" NM_015049 "trafficking protein, kinesin binding 2" TRAK2 66008 NM_015049 /// XM_006712714 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0050811 // GABA receptor binding // non-traceable author statement 202126_at AA156948 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA156948 /FEA=EST /DB_XREF=gi:1728563 /DB_XREF=est:zl19f02.s1 /CLONE=IMAGE:502395 /UG=Hs.198891 serinethreonine-protein kinase PRP4 homolog /FL=gb:U48736.1 gb:NM_003913.1 AA156948 pre-mRNA processing factor 4B PRPF4B 8899 NM_003913 /// NM_176800 /// XM_006715238 /// XR_241936 /// XR_241940 /// XR_241944 /// XR_241945 /// XR_241947 /// XR_241948 /// XR_241949 /// XR_427838 /// XR_427839 /// XR_427840 /// XR_427841 /// XR_427842 /// XR_427843 /// XR_427844 /// XR_427845 /// XR_427846 /// XR_427847 /// XR_427848 /// XR_427849 /// XR_427850 /// XR_427851 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202127_at AB011108 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB011108.1 /DEF=Homo sapiens mRNA for KIAA0536 protein, partial cds. /FEA=mRNA /GEN=KIAA0536 /PROD=KIAA0536 protein /DB_XREF=gi:3043595 /UG=Hs.198891 serinethreonine-protein kinase PRP4 homolog /FL=gb:U48736.1 gb:NM_003913.1" AB011108 pre-mRNA processing factor 4B PRPF4B 8899 NM_003913 /// NM_176800 /// XM_006715238 /// XR_241936 /// XR_241940 /// XR_241944 /// XR_241945 /// XR_241947 /// XR_241948 /// XR_241949 /// XR_427838 /// XR_427839 /// XR_427840 /// XR_427841 /// XR_427842 /// XR_427843 /// XR_427844 /// XR_427845 /// XR_427846 /// XR_427847 /// XR_427848 /// XR_427849 /// XR_427850 /// XR_427851 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202128_at NM_014821 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014821.1 /DEF=Homo sapiens KIAA0317 gene product (KIAA0317), mRNA. /FEA=mRNA /GEN=KIAA0317 /PROD=KIAA0317 gene product /DB_XREF=gi:7662051 /UG=Hs.20126 KIAA0317 gene product /FL=gb:AB002315.1 gb:NM_014821.1" NM_014821 apoptosis resistant E3 ubiquitin protein ligase 1 AREL1 9870 NM_001039479 /// NM_014821 /// XM_005268244 /// XM_006720344 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation 202129_s_at AW006290 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW006290 /FEA=EST /DB_XREF=gi:5855068 /DB_XREF=est:wq69f11.x1 /CLONE=IMAGE:2476557 /UG=Hs.209061 sudD (suppressor of bimD6, Aspergillus nidulans) homolog /FL=gb:AF013591.1 gb:NM_003831.1" AW006290 RIO kinase 3 RIOK3 8780 NM_003831 /// NM_145906 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007059 // chromosome segregation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 202130_at AA725102 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA725102 /FEA=EST /DB_XREF=gi:2742809 /DB_XREF=est:ai08h05.s1 /CLONE=1342233 /UG=Hs.209061 sudD (suppressor of bimD6, Aspergillus nidulans) homolog /FL=gb:AF013591.1 gb:NM_003831.1" AA725102 RIO kinase 3 RIOK3 8780 NM_003831 /// NM_145906 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007059 // chromosome segregation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 202131_s_at NM_003831 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003831.1 /DEF=Homo sapiens sudD (suppressor of bimD6, Aspergillus nidulans) homolog (SUDD), mRNA. /FEA=mRNA /GEN=SUDD /PROD=sudD (suppressor of bimD6, Aspergillus nidulans)homolog /DB_XREF=gi:4507298 /UG=Hs.209061 sudD (suppressor of bimD6, Aspergillus nidulans) homolog /FL=gb:AF013591.1 gb:NM_003831.1" NM_003831 RIO kinase 3 RIOK3 8780 NM_003831 /// NM_145906 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007059 // chromosome segregation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 202132_at AA081084 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA081084 /FEA=EST /DB_XREF=gi:1623002 /DB_XREF=est:zn32h12.s1 /CLONE=IMAGE:549191 /UG=Hs.24341 transcriptional co-activator with PDZ-binding motif (TAZ) /FL=gb:NM_015472.1 AA081084 WW domain containing transcription regulator 1 WWTR1 25937 NM_001168278 /// NM_001168280 /// NM_015472 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0017145 // stem cell division // inferred from direct assay /// 0032835 // glomerulus development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060390 // regulation of SMAD protein import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202133_at BF674349 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF674349 /FEA=EST /DB_XREF=gi:11948244 /DB_XREF=est:602137094F1 /CLONE=IMAGE:4273679 /UG=Hs.24341 transcriptional co-activator with PDZ-binding motif (TAZ) /FL=gb:NM_015472.1 BF674349 WW domain containing transcription regulator 1 WWTR1 25937 NM_001168278 /// NM_001168280 /// NM_015472 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0017145 // stem cell division // inferred from direct assay /// 0032835 // glomerulus development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060390 // regulation of SMAD protein import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202134_s_at NM_015472 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015472.1 /DEF=Homo sapiens transcriptional co-activator with PDZ-binding motif (TAZ) (TAZ), mRNA. /FEA=mRNA /GEN=TAZ /PROD=transcriptional co-activator with PDZ-bindingmotif (TAZ) /DB_XREF=gi:13346497 /UG=Hs.24341 transcriptional co-activator with PDZ-binding motif (TAZ) /FL=gb:NM_015472.1" NM_015472 WW domain containing transcription regulator 1 WWTR1 25937 NM_001168278 /// NM_001168280 /// NM_015472 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0017145 // stem cell division // inferred from direct assay /// 0032835 // glomerulus development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035414 // negative regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0060271 // cilium morphogenesis // inferred from electronic annotation /// 0060390 // regulation of SMAD protein import into nucleus // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202135_s_at NM_005735 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005735.2 /DEF=Homo sapiens ARP1 (actin-related protein 1, yeast) homolog B (centractin beta) (ACTR1B), mRNA. /FEA=mRNA /GEN=ACTR1B /PROD=actin-related protein 1B /DB_XREF=gi:13325060 /UG=Hs.2477 ARP1 (actin-related protein 1, yeast) homolog B (centractin beta) /FL=gb:NM_005735.2 gb:BC004374.1" NM_005735 "ARP1 actin-related protein 1 homolog B, centractin beta (yeast)" ACTR1B 10120 NM_005735 /// XM_005263854 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 202136_at BE250417 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE250417 /FEA=EST /DB_XREF=gi:9120528 /DB_XREF=est:600943460T1 /CLONE=IMAGE:2959935 /UG=Hs.301449 adenovirus 5 E1A binding protein /FL=gb:NM_006624.1 BE250417 "zinc finger, MYND-type containing 11" ZMYND11 10771 NM_001202464 /// NM_001202465 /// NM_001202466 /// NM_001202467 /// NM_001202468 /// NM_006624 /// NM_212479 /// XM_005252359 /// XM_005252360 /// XM_005252361 /// XM_005252362 /// XM_005252363 /// XM_006717376 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034243 // regulation of transcription elongation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0035064 // methylated histone binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202137_s_at NM_006624 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006624.1 /DEF=Homo sapiens adenovirus 5 E1A binding protein (BS69), mRNA. /FEA=mRNA /GEN=BS69 /PROD=adenovirus 5 E1A binding protein /DB_XREF=gi:5729745 /UG=Hs.301449 adenovirus 5 E1A binding protein /FL=gb:NM_006624.1" NM_006624 "zinc finger, MYND-type containing 11" ZMYND11 10771 NM_001202464 /// NM_001202465 /// NM_001202466 /// NM_001202467 /// NM_001202468 /// NM_006624 /// NM_212479 /// XM_005252359 /// XM_005252360 /// XM_005252361 /// XM_005252362 /// XM_005252363 /// XM_006717376 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0034243 // regulation of transcription elongation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0046329 // negative regulation of JNK cascade // inferred from mutant phenotype /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0035064 // methylated histone binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202138_x_at NM_006303 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006303.2 /DEF=Homo sapiens JTV1 gene (JTV1), mRNA. /FEA=mRNA /GEN=JTV1 /PROD=JTV1 /DB_XREF=gi:11125769 /UG=Hs.301613 JTV1 gene /FL=gb:NM_006303.2 gb:U24169.1 gb:BC002853.1" NM_006303 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 AIMP2 7965 NM_006303 /// XM_005249847 /// XM_005249848 /// XM_005249850 /// XM_006715772 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009605 // response to external stimulus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0045993 // negative regulation of translational initiation by iron // non-traceable author statement /// 0046501 // protoporphyrinogen IX metabolic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0046986 // negative regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060510 // Type II pneumocyte differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity" 202139_at NM_003689 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003689.1 /DEF=Homo sapiens aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2), mRNA. /FEA=mRNA /GEN=AKR7A2 /PROD=aldo-keto reductase family 7, member A2(aflatoxin aldehyde reductase) /DB_XREF=gi:4502020 /UG=Hs.6980 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) /FL=gb:BC004111.1 gb:AF026947.1 gb:NM_003689.1" NM_003689 "aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)" AKR7A2 8574 NM_003689 0005975 // carbohydrate metabolic process // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004032 // alditol:NADP+ 1-oxidoreductase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019119 // phenanthrene-9,10-epoxide hydrolase activity // inferred from direct assay" 202140_s_at NM_003992 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003992.1 /DEF=Homo sapiens CDC-like kinase 3 (CLK3), transcript variant phclk3, mRNA. /FEA=mRNA /GEN=CLK3 /PROD=CDC-like kinase 3 isoform hclk3 /DB_XREF=gi:4502884 /UG=Hs.73987 CDC-like kinase 3 /FL=gb:BC002555.1 gb:NM_003992.1 gb:L29217.1" NM_003992 CDC-like kinase 3 CLK3 1198 NM_001130028 /// NM_001292 /// NM_003992 /// XM_005254151 /// XM_005254152 /// XM_005254153 /// XM_005254154 /// XM_006720383 /// XM_006720384 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202141_s_at BC003090 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003090.1 /DEF=Homo sapiens, COP9 homolog, clone MGC:1297, mRNA, complete cds. /FEA=mRNA /PROD=COP9 homolog /DB_XREF=gi:13111846 /UG=Hs.75193 COP9 homolog /FL=gb:BC003090.1 gb:U51205.1 gb:NM_006710.1" BC003090 COP9 signalosome subunit 8 COPS8 10920 NM_006710 /// NM_198189 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202142_at BC003090 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003090.1 /DEF=Homo sapiens, COP9 homolog, clone MGC:1297, mRNA, complete cds. /FEA=mRNA /PROD=COP9 homolog /DB_XREF=gi:13111846 /UG=Hs.75193 COP9 homolog /FL=gb:BC003090.1 gb:U51205.1 gb:NM_006710.1" BC003090 COP9 signalosome subunit 8 COPS8 10920 NM_006710 /// NM_198189 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202143_s_at NM_006710 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006710.1 /DEF=Homo sapiens COP9 homolog (COP9), mRNA. /FEA=mRNA /GEN=COP9 /PROD=COP9 homolog /DB_XREF=gi:5729778 /UG=Hs.75193 COP9 homolog /FL=gb:BC003090.1 gb:U51205.1 gb:NM_006710.1" NM_006710 COP9 signalosome subunit 8 COPS8 10920 NM_006710 /// NM_198189 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010388 // cullin deneddylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202144_s_at NM_000026 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000026.1 /DEF=Homo sapiens adenylosuccinate lyase (ADSL), mRNA. /FEA=mRNA /GEN=ADSL /PROD=adenylosuccinate lyase /DB_XREF=gi:4557268 /UG=Hs.75527 adenylosuccinate lyase /FL=gb:AF067853.1 gb:NM_000026.1" NM_000026 adenylosuccinate lyase ADSL 158 NM_000026 /// NM_001123378 0001666 // response to hypoxia // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006163 // purine nucleotide metabolic process // inferred from electronic annotation /// 0006164 // purine nucleotide biosynthetic process // inferred by curator /// 0006167 // AMP biosynthetic process // inferred from direct assay /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from direct assay /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009152 // purine ribonucleotide biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044208 // 'de novo' AMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0003824 // catalytic activity // inferred from electronic annotation /// 0004018 // N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity // inferred from direct assay /// 0004018 // N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0070626 // (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity // inferred from electronic annotation" 202145_at NM_002346 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002346.1 /DEF=Homo sapiens lymphocyte antigen 6 complex, locus E (LY6E), mRNA. /FEA=mRNA /GEN=LY6E /PROD=lymphocyte antigen 6 complex, locus E /DB_XREF=gi:4505048 /UG=Hs.77667 lymphocyte antigen 6 complex, locus E /FL=gb:U42376.1 gb:U56145.1 gb:NM_002346.1" NM_002346 "lymphocyte antigen 6 complex, locus E" LY6E 4061 NM_001127213 /// NM_002346 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0042415 // norepinephrine metabolic process // inferred from electronic annotation /// 0048242 // epinephrine secretion // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 202146_at AA747426 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA747426 /FEA=EST /DB_XREF=gi:2787384 /DB_XREF=est:nx88e08.s1 /CLONE=IMAGE:1269350 /UG=Hs.7879 interferon-related developmental regulator 1 /FL=gb:BC001272.1 gb:NM_001550.1 AA747426 interferon-related developmental regulator 1 IFRD1 3475 NM_001007245 /// NM_001197079 /// NM_001197080 /// NM_001550 /// NR_120333 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007518 // myoblast fate determination // traceable author statement /// 0007527 // adult somatic muscle development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 202147_s_at NM_001550 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001550.1 /DEF=Homo sapiens interferon-related developmental regulator 1 (IFRD1), mRNA. /FEA=mRNA /GEN=IFRD1 /PROD=interferon-related developmental regulator 1 /DB_XREF=gi:4504606 /UG=Hs.7879 interferon-related developmental regulator 1 /FL=gb:BC001272.1 gb:NM_001550.1" NM_001550 interferon-related developmental regulator 1 IFRD1 3475 NM_001007245 /// NM_001197079 /// NM_001197080 /// NM_001550 /// NR_120333 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007518 // myoblast fate determination // traceable author statement /// 0007527 // adult somatic muscle development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 202148_s_at NM_006907 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006907.1 /DEF=Homo sapiens pyrroline-5-carboxylate reductase 1 (PYCR1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PYCR1 /PROD=pyrroline-5-carboxylate reductase 1 /DB_XREF=gi:5902035 /UG=Hs.79217 pyrroline-5-carboxylate reductase 1 /FL=gb:M77836.1 gb:NM_006907.1" NM_006907 pyrroline-5-carboxylate reductase 1 PYCR1 5831 NM_001282279 /// NM_001282280 /// NM_001282281 /// NM_006907 /// NM_153824 /// XM_005256381 /// XM_006722286 0006561 // proline biosynthetic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046168 // glycerol-3-phosphate catabolic process // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055129 // L-proline biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement "0004735 // pyrroline-5-carboxylate reductase activity // inferred from direct assay /// 0004735 // pyrroline-5-carboxylate reductase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051287 // NAD binding // inferred from electronic annotation" 202149_at AL136139 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL136139 /DEF=Human DNA sequence from clone RP4-761I2 on chromosome 6 Contains 3 part of the gene for enhancer of filamentation (HEF1), ESTs, STSs and CpG islands /FEA=mRNA /DB_XREF=gi:8217463 /UG=Hs.80261 enhancer of filamentation 1 (cas-like docking; Crk-associated substrate related) /FL=gb:L43821.1 gb:U64317.1 gb:NM_006403.1" AL136139 "neural precursor cell expressed, developmentally down-regulated 9" NEDD9 4739 NM_001142393 /// NM_001271033 /// NM_006403 /// NM_182966 /// NR_073131 0007010 // cytoskeleton organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202150_s_at U64317 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U64317.1 /DEF=Human Crk-associated substrate related protein Cas-L mRNA, complete cds. /FEA=mRNA /PROD=Crk-associated substrate related protein Cas-L /DB_XREF=gi:1490786 /UG=Hs.80261 enhancer of filamentation 1 (cas-like docking; Crk-associated substrate related) /FL=gb:L43821.1 gb:U64317.1 gb:NM_006403.1" U64317 "neural precursor cell expressed, developmentally down-regulated 9" NEDD9 4739 NM_001142393 /// NM_001271033 /// NM_006403 /// NM_182966 /// NR_073131 0007010 // cytoskeleton organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202151_s_at NM_016172 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016172.1 /DEF=Homo sapiens putative glialblastoma cell differentiation-related (GDBR1), mRNA. /FEA=mRNA /GEN=GDBR1 /PROD=putative glialblastoma celldifferentiation-related protein /DB_XREF=gi:7705380 /UG=Hs.9194 putative glialblastoma cell differentiation-related /FL=gb:BC004967.1 gb:AF176796.1 gb:NM_016172.1" NM_016172 UBA domain containing 1 UBAC1 10422 NM_016172 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202152_x_at NM_003367 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003367.1 /DEF=Homo sapiens upstream transcription factor 2, c-fos interacting (USF2), mRNA. /FEA=mRNA /GEN=USF2 /PROD=upstream transcription factor 2, c-fosinteracting /DB_XREF=gi:4507846 /UG=Hs.93649 upstream transcription factor 2, c-fos interacting /FL=gb:NM_003367.1" NM_003367 "upstream transcription factor 2, c-fos interacting" USF2 7392 NM_003367 /// NM_207291 /// XM_005259197 "0000430 // regulation of transcription from RNA polymerase II promoter by glucose // inferred by curator /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from mutant phenotype /// 0000432 // positive regulation of transcription from RNA polymerase II promoter by glucose // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0007595 // lactation // inferred from electronic annotation /// 0019086 // late viral transcription // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 202153_s_at NM_016553 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016553.1 /DEF=Homo sapiens hypothetical protein (DKFZp547L134), mRNA. /FEA=mRNA /GEN=DKFZp547L134 /PROD=hypothetical protein /DB_XREF=gi:7705354 /UG=Hs.9877 hypothetical protein /FL=gb:AL162061.1 gb:NM_016553.1" NM_016553 nucleoporin 62kDa NUP62 23636 NM_001193357 /// NM_012346 /// NM_016553 /// NM_153718 /// NM_153719 "0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from mutant phenotype /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008645 // hexose transport // traceable author statement /// 0009755 // hormone-mediated signaling pathway // non-traceable author statement /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043069 // negative regulation of programmed cell death // inferred from direct assay /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046578 // regulation of Ras protein signal transduction // non-traceable author statement /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement" 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // inferred from sequence or structural similarity /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031074 // nucleocytoplasmic shuttling complex // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0046930 // pore complex // non-traceable author statement 0003682 // chromatin binding // non-traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from direct assay /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from sequence or structural similarity /// 0051425 // PTB domain binding // inferred from electronic annotation 202154_x_at NM_006086 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006086.1 /DEF=Homo sapiens tubulin, beta, 4 (TUBB4), mRNA. /FEA=mRNA /GEN=TUBB4 /PROD=tubulin, beta, 4 /DB_XREF=gi:5174736 /UG=Hs.159154 tubulin, beta, 4 /FL=gb:BC000748.1 gb:U47634.1 gb:NM_006086.1" NM_006086 "tubulin, beta 3 class III" TUBB3 10381 NM_001197181 /// NM_006086 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 202155_s_at NM_005085 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005085.1 /DEF=Homo sapiens nucleoporin 214kD (CAIN) (NUP214), mRNA. /FEA=mRNA /GEN=NUP214 /PROD=nucleoporin 214kD (CAIN) /DB_XREF=gi:4826873 /UG=Hs.170285 nucleoporin 214kD (CAIN) /FL=gb:NM_005085.1" NM_005085 nucleoporin 214kDa NUP214 8021 NM_005085 /// XM_005272216 /// XM_005272217 /// XM_005272218 /// XM_005272219 /// XM_006717292 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005487 // nucleocytoplasmic transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202156_s_at N36839 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N36839 /FEA=EST /DB_XREF=gi:1157981 /DB_XREF=est:yy35f07.s1 /CLONE=IMAGE:273253 /UG=Hs.211610 CUG triplet repeat, RNA-binding protein 2 /FL=gb:U69546.1 gb:AF036956.1 gb:AF090694.1 gb:NM_006561.1" N36839 "CUGBP, Elav-like family member 2" CELF2 10659 NM_001025076 /// NM_001025077 /// NM_001083591 /// NM_006561 /// XM_005252348 /// XM_005252349 /// XM_005252351 /// XM_005252354 /// XM_005252357 /// XM_005252358 /// XM_006717365 /// XM_006717366 /// XM_006717367 /// XM_006717368 /// XM_006717369 /// XM_006717370 /// XM_006717371 /// XM_006717372 /// XM_006717373 /// XM_006717374 /// XM_006717375 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008016 // regulation of heart contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202157_s_at U69546 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U69546.1 /DEF=Homo sapiens RNA-binding protein BRUNOL3 (BRUNOL3) mRNA, complete cds. /FEA=mRNA /GEN=BRUNOL3 /PROD=RNA-binding protein BRUNOL3 /DB_XREF=gi:1568642 /UG=Hs.211610 CUG triplet repeat, RNA-binding protein 2 /FL=gb:U69546.1 gb:AF036956.1 gb:AF090694.1 gb:NM_006561.1" U69546 "CUGBP, Elav-like family member 2" CELF2 10659 NM_001025076 /// NM_001025077 /// NM_001083591 /// NM_006561 /// XM_005252348 /// XM_005252349 /// XM_005252351 /// XM_005252354 /// XM_005252357 /// XM_005252358 /// XM_006717365 /// XM_006717366 /// XM_006717367 /// XM_006717368 /// XM_006717369 /// XM_006717370 /// XM_006717371 /// XM_006717372 /// XM_006717373 /// XM_006717374 /// XM_006717375 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008016 // regulation of heart contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202158_s_at NM_006561 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006561.1 /DEF=Homo sapiens CUG triplet repeat, RNA-binding protein 2 (CUGBP2), mRNA. /FEA=mRNA /GEN=CUGBP2 /PROD=CUG triplet repeat, RNA-binding protein 2 /DB_XREF=gi:5729815 /UG=Hs.211610 CUG triplet repeat, RNA-binding protein 2 /FL=gb:U69546.1 gb:AF036956.1 gb:AF090694.1 gb:NM_006561.1" NM_006561 "CUGBP, Elav-like family member 2" CELF2 10659 NM_001025076 /// NM_001025077 /// NM_001083591 /// NM_006561 /// XM_005252348 /// XM_005252349 /// XM_005252351 /// XM_005252354 /// XM_005252357 /// XM_005252358 /// XM_006717365 /// XM_006717366 /// XM_006717367 /// XM_006717368 /// XM_006717369 /// XM_006717370 /// XM_006717371 /// XM_006717372 /// XM_006717373 /// XM_006717374 /// XM_006717375 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008016 // regulation of heart contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 202159_at NM_004461 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004461.1 /DEF=Homo sapiens phenylalanine-tRNA synthetase-like (FARSL), mRNA. /FEA=mRNA /GEN=FARSL /PROD=phenylalanine-tRNA synthetase-like protein /DB_XREF=gi:4758339 /UG=Hs.23111 phenylalanine-tRNA synthetase-like /FL=gb:U07424.1 gb:AF042347.1 gb:NM_004461.1 gb:D84471.1" NM_004461 "phenylalanyl-tRNA synthetase, alpha subunit" FARSA 2193 NM_004461 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202160_at NM_004380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004380.1 /DEF=Homo sapiens CREB binding protein (Rubinstein-Taybi syndrome) (CREBBP), mRNA. /FEA=mRNA /GEN=CREBBP /PROD=CREB binding protein /DB_XREF=gi:4758055 /UG=Hs.23598 CREB binding protein (Rubinstein-Taybi syndrome) /FL=gb:U47741.1 gb:NM_004380.1" NM_004380 CREB binding protein CREBBP 1387 NM_001079846 /// NM_004380 /// XM_005255124 /// XM_005255125 /// XM_006720848 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001666 // response to hypoxia // traceable author statement /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008589 // regulation of smoothened signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042592 // homeostatic process // non-traceable author statement /// 0042733 // embryonic digit morphogenesis // traceable author statement /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0060177 // regulation of angiotensin metabolic process // inferred from electronic annotation /// 0060298 // positive regulation of sarcomere organization // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement" 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from electronic annotation "0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001102 // RNA polymerase II activating transcription factor binding // traceable author statement /// 0001105 // RNA polymerase II transcription coactivator activity // traceable author statement /// 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0001191 // RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from physical interaction /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043426 // MRF binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation" 202161_at NM_002741 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002741.1 /DEF=Homo sapiens protein kinase C-like 1 (PRKCL1), mRNA. /FEA=mRNA /GEN=PRKCL1 /PROD=protein kinase C-like 1 /DB_XREF=gi:4506072 /UG=Hs.2499 protein kinase C-like 1 /FL=gb:U33053.1 gb:NM_002741.1 gb:D26181.1" NM_002741 protein kinase N1 PKN1 5585 NM_002741 /// NM_213560 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0010631 // epithelial cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035407 // histone H3-T11 phosphorylation // inferred from direct assay /// 2000145 // regulation of cell motility // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017049 // GTP-Rho binding // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0035402 // histone kinase activity (H3-T11 specific) // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from direct assay" 202162_s_at AI769416 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI769416 /FEA=EST /DB_XREF=gi:5235925 /DB_XREF=est:wj13f08.x1 /CLONE=IMAGE:2402727 /UG=Hs.26703 CCR4-NOT transcription complex, subunit 8 /FL=gb:AF053318.1 gb:NM_004779.1 gb:AL122045.1 gb:AF180476.1" AI769416 "CCR4-NOT transcription complex, subunit 8" CNOT8 9337 NM_004779 /// XM_005268526 /// XM_005268527 /// XM_005268528 /// XM_006714807 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation" 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202163_s_at NM_004779 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004779.1 /DEF=Homo sapiens CCR4-NOT transcription complex, subunit 8 (CNOT8), mRNA. /FEA=mRNA /GEN=CNOT8 /PROD=CCR4-NOT transcription complex, subunit 8 /DB_XREF=gi:4758945 /UG=Hs.26703 CCR4-NOT transcription complex, subunit 8 /FL=gb:AF053318.1 gb:NM_004779.1 gb:AL122045.1 gb:AF180476.1" NM_004779 "CCR4-NOT transcription complex, subunit 8" CNOT8 9337 NM_004779 /// XM_005268526 /// XM_005268527 /// XM_005268528 /// XM_006714807 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation" 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202164_s_at AF180476 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF180476.1 /DEF=Homo sapiens CALIFp (CALIF) mRNA, complete cds. /FEA=mRNA /GEN=CALIF /PROD=CALIFp /DB_XREF=gi:6856208 /UG=Hs.26703 CCR4-NOT transcription complex, subunit 8 /FL=gb:AF053318.1 gb:NM_004779.1 gb:AL122045.1 gb:AF180476.1" AF180476 "CCR4-NOT transcription complex, subunit 8" CNOT8 9337 NM_004779 /// XM_005268526 /// XM_005268527 /// XM_005268528 /// XM_006714807 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0035195 // gene silencing by miRNA // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // inferred from direct assay /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation" 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202165_at BF966540 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF966540 /FEA=EST /DB_XREF=gi:12333755 /DB_XREF=est:602287009T1 /CLONE=IMAGE:4375586 /UG=Hs.267819 protein phosphatase 1, regulatory (inhibitor) subunit 2 /FL=gb:NM_006241.1" BF966540 "protein phosphatase 1, regulatory (inhibitor) subunit 2" PPP1R2 5504 NM_001291504 /// NM_001291505 /// NM_006241 /// XM_006713682 /// XM_006713683 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0004865 // protein serine/threonine phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202166_s_at NM_006241 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006241.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 2 (PPP1R2), mRNA. /FEA=mRNA /GEN=PPP1R2 /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 2 /DB_XREF=gi:5453945 /UG=Hs.267819 protein phosphatase 1, regulatory (inhibitor) subunit 2 /FL=gb:NM_006241.1" NM_006241 "protein phosphatase 1, regulatory (inhibitor) subunit 2" PPP1R2 5504 NM_001291504 /// NM_001291505 /// NM_006241 /// XM_006713682 /// XM_006713683 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043666 // regulation of phosphoprotein phosphatase activity // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0004865 // protein serine/threonine phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202167_s_at NM_022362 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022362.1 /DEF=Homo sapiens MMS19 (MET18 S. cerevisiae)-like (MMS19L), mRNA. /FEA=mRNA /GEN=MMS19L /PROD=MMS19 (MET18 S. cerevisiae)-like /DB_XREF=gi:13375625 /UG=Hs.288891 MMS19 (MET18 S. cerevisiae)-like /FL=gb:NM_022362.1" NM_022362 MMS19 nucleotide excision repair homolog (S. cerevisiae) MMS19 64210 NM_001289403 /// NM_001289404 /// NM_001289405 /// NM_022362 /// XM_005270035 /// XM_005270041 /// XM_006717944 /// XM_006717945 /// XR_428713 "0000160 // phosphorelay signal transduction system // non-traceable author statement /// 0006259 // DNA metabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // non-traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0009725 // response to hormone // non-traceable author statement /// 0016226 // iron-sulfur cluster assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005675 // holo TFIIH complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0071817 // MMXD complex // inferred from direct assay /// 0097361 // CIA complex // inferred from direct assay "0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement" 202168_at NM_003187 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003187.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, G, 32kD (TAF2G), mRNA. /FEA=mRNA /GEN=TAF2G /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, G, 32kD /DB_XREF=gi:4507350 /UG=Hs.60679 TATA box binding protein (TBP)-associated factor, RNA polymerase II, G, 32kD /FL=gb:BC003400.1 gb:NM_003187.1 gb:U21858.1 gb:U25112.1 gb:U30504.1" NM_003187 "adenylate kinase 6 /// TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa" AK6 /// TAF9 6880 /// 102157402 NM_001015891 /// NM_001015892 /// NM_003187 /// NM_016283 "0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred by curator /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0060760 // positive regulation of response to cytokine stimulus // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred by curator" 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202169_s_at AF302110 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF302110.1 /DEF=Homo sapiens alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase mRNA, complete cds. /FEA=mRNA /PROD=alpha-aminoadipic semialdehydedehydrogenase-phosphopantetheinyl transferase /DB_XREF=gi:11120434 /UG=Hs.64595 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase /FL=gb:AF302110.1 gb:AF136978.1 gb:AF151838.1 gb:AF151057.1 gb:NM_015423.1 gb:AF201943.1" AF302110 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase AASDHPPT 60496 NM_015423 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009059 // macromolecule biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008897 // holo-[acyl-carrier-protein] synthase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202170_s_at AF151057 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF151057.1 /DEF=Homo sapiens HSPC223 mRNA, complete cds. /FEA=mRNA /PROD=HSPC223 /DB_XREF=gi:7106835 /UG=Hs.64595 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase /FL=gb:AF302110.1 gb:AF136978.1 gb:AF151838.1 gb:AF151057.1 gb:NM_015423.1 gb:AF201943.1" AF151057 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase AASDHPPT 60496 NM_015423 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009059 // macromolecule biosynthetic process // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008897 // holo-[acyl-carrier-protein] synthase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202171_at AU146275 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU146275 /FEA=EST /DB_XREF=gi:11007796 /DB_XREF=est:AU146275 /CLONE=HEMBB1000004 /UG=Hs.6557 zinc finger protein 161 /FL=gb:D28118.1 gb:NM_007146.1 AU146275 vascular endothelial zinc finger 1 VEZF1 7716 NM_007146 /// XM_005257643 /// XM_005257644 "0001525 // angiogenesis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006968 // cellular defense response // traceable author statement" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202172_at BG035116 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG035116 /FEA=EST /DB_XREF=gi:12428927 /DB_XREF=est:602324811F1 /CLONE=IMAGE:4412907 /UG=Hs.6557 zinc finger protein 161 /FL=gb:D28118.1 gb:NM_007146.1 BG035116 vascular endothelial zinc finger 1 VEZF1 7716 NM_007146 /// XM_005257643 /// XM_005257644 "0001525 // angiogenesis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006968 // cellular defense response // traceable author statement" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202173_s_at NM_007146 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007146.1 /DEF=Homo sapiens zinc finger protein 161 (ZNF161), mRNA. /FEA=mRNA /GEN=ZNF161 /PROD=zinc finger protein 161 /DB_XREF=gi:6005967 /UG=Hs.6557 zinc finger protein 161 /FL=gb:D28118.1 gb:NM_007146.1" NM_007146 vascular endothelial zinc finger 1 VEZF1 7716 NM_007146 /// XM_005257643 /// XM_005257644 "0001525 // angiogenesis // inferred from electronic annotation /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006968 // cellular defense response // traceable author statement" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202174_s_at NM_006197 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006197.1 /DEF=Homo sapiens pericentriolar material 1 (PCM1), mRNA. /FEA=mRNA /GEN=PCM1 /PROD=pericentriolar material 1 /DB_XREF=gi:5453855 /UG=Hs.75737 pericentriolar material 1 /FL=gb:L27841.1 gb:NM_006197.1" NM_006197 pericentriolar material 1 PCM1 5108 NM_006197 /// XM_005273509 /// XM_005273512 /// XM_005273519 /// XM_005273520 /// XM_005273521 /// XM_006716336 /// XM_006716337 /// XM_006716338 /// XM_006716339 /// XM_006716340 /// XM_006716341 /// XM_006716342 /// XM_006716343 /// XM_006716344 /// XM_006716345 /// XM_006716346 /// XM_006716347 /// XM_006716348 /// XM_006716349 /// XM_006716350 /// XR_428310 "0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001838 // embryonic epithelial tube formation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from electronic annotation /// 0007158 // neuron cell-cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022027 // interkinetic nuclear migration // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from mutant phenotype /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from sequence or structural similarity /// 0034454 // microtubule anchoring at centrosome // inferred from electronic annotation /// 0035735 // intraciliary transport involved in cilium morphogenesis // inferred from mutant phenotype /// 0035799 // ureter maturation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048265 // response to pain // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0048484 // enteric nervous system development // inferred from electronic annotation /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from electronic annotation /// 0061146 // Peyer's patch morphogenesis // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0071539 // protein localization to centrosome // inferred from sequence or structural similarity /// 0072300 // positive regulation of metanephric glomerulus development // inferred from electronic annotation /// 0072300 // positive regulation of metanephric glomerulus development // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype /// 0097021 // lymphocyte migration into lymphoid organs // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement" 0000242 // pericentriolar material // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031513 // nonmotile primary cilium // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity" 202175_at NM_024536 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024536.1 /DEF=Homo sapiens hypothetical protein FLJ22678 (FLJ22678), mRNA. /FEA=mRNA /GEN=FLJ22678 /PROD=hypothetical protein FLJ22678 /DB_XREF=gi:13375692 /UG=Hs.7718 hypothetical protein FLJ22678 /FL=gb:NM_024536.1" NM_024536 chondroitin polymerizing factor CHPF 79586 NM_001195731 /// NM_024536 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation "0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047238 // glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0050510 // N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity // inferred from electronic annotation" 202176_at NM_000122 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000122.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), mRNA. /FEA=mRNA /GEN=ERCC3 /PROD=excision repair cross-complementing rodentrepair deficiency, complementation group 3 (xerodermapigmentosum group B complementing) /DB_XREF=gi:4557562 /UG=Hs.77929 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) /FL=gb:M31899.1 gb:NM_000122.1" NM_000122 excision repair cross-complementation group 3 ERCC3 2071 NM_000122 /// XM_005263618 "0000717 // nucleotide-excision repair, DNA duplex unwinding // inferred from mutant phenotype /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006265 // DNA topological change // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from direct assay /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0008104 // protein localization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from mutant phenotype /// 0009650 // UV protection // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0033683 // nucleotide-excision repair, DNA incision // inferred from mutant phenotype /// 0035315 // hair cell differentiation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement /// 1901990 // regulation of mitotic cell cycle phase transition // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005675 // holo TFIIH complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // non-traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // inferred from mutant phenotype /// 0008134 // transcription factor binding // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0032564 // dATP binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0043138 // 3'-5' DNA helicase activity // inferred from direct assay /// 0043138 // 3'-5' DNA helicase activity // inferred from mutant phenotype /// 0047485 // protein N-terminus binding // inferred from physical interaction 202177_at NM_000820 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000820.1 /DEF=Homo sapiens growth arrest-specific 6 (GAS6), mRNA. /FEA=mRNA /GEN=GAS6 /PROD=growth arrest-specific 6 /DB_XREF=gi:4557616 /UG=Hs.78501 growth arrest-specific 6 /FL=gb:L13720.1 gb:NM_000820.1" NM_000820 growth arrest-specific 6 GAS6 2621 NM_000820 /// NM_001143945 /// NM_001143946 "0001764 // neuron migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006909 // phagocytosis // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009267 // cellular response to starvation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010934 // macrophage cytokine production // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019064 // fusion of virus membrane with host plasma membrane // inferred from direct assay /// 0019079 // viral genome replication // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from sequence or structural similarity /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032715 // negative regulation of interleukin-6 production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033159 // negative regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035754 // B cell chemotaxis // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043277 // apoptotic cell clearance // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046718 // viral entry into host cell // inferred from direct assay /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0046827 // positive regulation of protein export from nucleus // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0050711 // negative regulation of interleukin-1 secretion // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070168 // negative regulation of biomineral tissue development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070527 // platelet aggregation // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071307 // cellular response to vitamin K // inferred from direct assay /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 0097241 // hematopoietic stem cell migration to bone marrow // inferred from direct assay /// 1900142 // negative regulation of oligodendrocyte apoptotic process // inferred from direct assay /// 1900165 // negative regulation of interleukin-6 secretion // inferred from direct assay /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from direct assay /// 2000533 // negative regulation of renal albumin absorption // inferred from sequence or structural similarity /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0001786 // phosphatidylserine binding // inferred from direct assay /// 0005102 // receptor binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048018 // receptor agonist activity // inferred from direct assay /// 0060090 // binding, bridging // inferred from direct assay" 202178_at NM_002744 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002744.2 /DEF=Homo sapiens protein kinase C, zeta (PRKCZ), mRNA. /FEA=mRNA /GEN=PRKCZ /PROD=protein kinase C, zeta /DB_XREF=gi:10864649 /UG=Hs.78793 protein kinase C, zeta /FL=gb:NM_002744.2 gb:L14283.1" NM_002744 "protein kinase C, zeta" PRKCZ 5590 NM_001033581 /// NM_001033582 /// NM_001242874 /// NM_002744 /// XM_006710764 /// XM_006710765 /// XM_006710766 /// XM_006710767 /// XM_006710768 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030168 // platelet activation // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // inferred from electronic annotation /// 0032148 // activation of protein kinase B activity // inferred from electronic annotation /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0051222 // positive regulation of protein transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051346 // negative regulation of hydrolase activity // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070528 // protein kinase C signaling // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000553 // positive regulation of T-helper 2 cell cytokine production // inferred from sequence or structural similarity /// 2000664 // positive regulation of interleukin-5 secretion // inferred from sequence or structural similarity /// 2000667 // positive regulation of interleukin-13 secretion // inferred from sequence or structural similarity /// 2001181 // positive regulation of interleukin-10 secretion // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030054 // cell junction // traceable author statement /// 0031252 // cell leading edge // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045179 // apical cortex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043560 // insulin receptor substrate binding // inferred by curator /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation" 202179_at NM_000386 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000386.1 /DEF=Homo sapiens bleomycin hydrolase (BLMH), mRNA. /FEA=mRNA /GEN=BLMH /PROD=bleomycin hydrolase /DB_XREF=gi:4557366 /UG=Hs.78943 bleomycin hydrolase /FL=gb:BC003616.1 gb:NM_000386.1" NM_000386 bleomycin hydrolase BLMH 642 NM_000386 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004177 // aminopeptidase activity // traceable author statement /// 0004180 // carboxypeptidase activity // traceable author statement /// 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 202180_s_at NM_017458 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017458.1 /DEF=Homo sapiens major vault protein (MVP), transcript variant 1, mRNA. /FEA=mRNA /GEN=MVP /PROD=major vault protein /DB_XREF=gi:9665254 /UG=Hs.80680 major vault protein /FL=gb:NM_017458.1" NM_017458 major vault protein MVP 9961 NM_001293204 /// NM_001293205 /// NM_005115 /// NM_017458 0006810 // transport // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0023057 // negative regulation of signaling // inferred from direct assay /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0038127 // ERBB signaling pathway // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0061099 // negative regulation of protein tyrosine kinase activity // inferred from direct assay /// 0072376 // protein activation cascade // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from direct assay 202181_at NM_014734 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014734.1 /DEF=Homo sapiens KIAA0247 gene product (KIAA0247), mRNA. /FEA=mRNA /GEN=KIAA0247 /PROD=KIAA0247 gene product /DB_XREF=gi:7662019 /UG=Hs.82426 KIAA0247 gene product /FL=gb:D87434.1 gb:NM_014734.1" NM_014734 KIAA0247 KIAA0247 9766 NM_014734 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202182_at NM_021078 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021078.1 /DEF=Homo sapiens GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 (GCN5L2), mRNA. /FEA=mRNA /GEN=GCN5L2 /PROD=GCN5 (general control of amino-acid synthesis,yeast, homolog)-like 2 /DB_XREF=gi:10835100 /UG=Hs.101067 GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 /FL=gb:NM_021078.1" NM_021078 K(lysine) acetyltransferase 2A KAT2A 2648 NM_021078 /// XM_006721817 /// XM_006721818 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0016578 // histone deubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0022037 // metencephalon development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043983 // histone H4-K12 acetylation // inferred from electronic annotation /// 0044154 // histone H3-K14 acetylation // inferred from electronic annotation" 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0072686 // mitotic spindle // inferred from electronic annotation "0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0010484 // H3 histone acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043997 // histone acetyltransferase activity (H4-K12 specific) // inferred from electronic annotation" 202183_s_at NM_007317 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007317.1 /DEF=Homo sapiens kinesin-like 4 (KNSL4), mRNA. /FEA=mRNA /GEN=KNSL4 /PROD=kinesin-like 4 /DB_XREF=gi:6453817 /UG=Hs.119324 kinesin-like 4 /FL=gb:BC004352.1 gb:AB017430.2 gb:L29096.1 gb:NM_007317.1" NM_007317 kinesin family member 22 KIF22 3835 NM_001256269 /// NM_001256270 /// NM_007317 /// XR_243280 0006281 // DNA repair // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007067 // mitotic nuclear division // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0000776 // kinetochore // traceable author statement /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 202184_s_at NM_018230 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018230.1 /DEF=Homo sapiens hypothetical protein FLJ10814 (FLJ10814), mRNA. /FEA=mRNA /GEN=FLJ10814 /PROD=hypothetical protein FLJ10814 /DB_XREF=gi:8922689 /UG=Hs.12457 hypothetical protein FLJ10814 /FL=gb:NM_018230.1" NM_018230 nucleoporin 133kDa NUP133 55746 NM_018230 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006999 // nuclear pore organization // inferred from mutant phenotype /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement" 0005487 // nucleocytoplasmic transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202185_at NM_001084 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001084.1 /DEF=Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3), mRNA. /FEA=mRNA /GEN=PLOD3 /PROD=procollagen-lysine, 2-oxoglutarate 5-dioxygenase3v /DB_XREF=gi:4505890 /UG=Hs.153357 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 /FL=gb:AF046889.1 gb:AF068229.1 gb:NM_001084.1" NM_001084 "procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3" PLOD3 8985 NM_001084 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001886 // endothelial cell morphogenesis // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0048730 // epidermis morphogenesis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0070831 // basement membrane assembly // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0033823 // procollagen glucosyltransferase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050211 // procollagen galactosyltransferase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation" 202186_x_at AI803525 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI803525 /FEA=EST /DB_XREF=gi:5368985 /DB_XREF=est:tc42h07.x1 /CLONE=IMAGE:2067325 /UG=Hs.155079 protein phosphatase 2, regulatory subunit B (B56), alpha isoform /FL=gb:L42373.1 gb:NM_006243.1" AI803525 "protein phosphatase 2, regulatory subunit B', alpha" PPP2R5A 5525 NM_001199756 /// NM_006243 0007165 // signal transduction // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090219 // negative regulation of lipid kinase activity // inferred from mutant phenotype "0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0031430 // M band // inferred from sequence or structural similarity" 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 202187_s_at NM_006243 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006243.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), alpha isoform (PPP2R5A), mRNA. /FEA=mRNA /GEN=PPP2R5A /PROD=protein phosphatase 2, regulatory subunit B(B56), alpha isoform /DB_XREF=gi:5453949 /UG=Hs.155079 protein phosphatase 2, regulatory subunit B (B56), alpha isoform /FL=gb:L42373.1 gb:NM_006243.1" NM_006243 "protein phosphatase 2, regulatory subunit B', alpha" PPP2R5A 5525 NM_001199756 /// NM_006243 0007165 // signal transduction // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090219 // negative regulation of lipid kinase activity // inferred from mutant phenotype "0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0031430 // M band // inferred from sequence or structural similarity" 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 202188_at NM_014669 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014669.1 /DEF=Homo sapiens KIAA0095 gene product (KIAA0095), mRNA. /FEA=mRNA /GEN=KIAA0095 /PROD=KIAA0095 gene product /DB_XREF=gi:7661901 /UG=Hs.155314 KIAA0095 gene product /FL=gb:D42085.1 gb:NM_014669.1" NM_014669 nucleoporin 93kDa NUP93 9688 NM_001242795 /// NM_001242796 /// NM_014669 /// XM_005256263 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype 202189_x_at NM_002819 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002819.1 /DEF=Homo sapiens polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) (PTB), mRNA. /FEA=mRNA /GEN=PTB /PROD=polypyrimidine tract binding protein(heterogeneous nuclear ribonucleoprotein I) /DB_XREF=gi:4506242 /UG=Hs.172550 polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) /FL=gb:NM_002819.1" NM_002819 microRNA 4745 /// polypyrimidine tract binding protein 1 MIR4745 /// PTBP1 5725 /// 100616459 NM_002819 /// NM_031990 /// NM_031991 /// NM_175847 /// NR_039900 /// XM_005259597 /// XM_005259598 /// XR_244034 /// XR_244035 "0000380 // alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033119 // negative regulation of RNA splicing // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0051148 // negative regulation of muscle cell differentiation // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008187 // poly-pyrimidine tract binding // traceable author statement /// 0036002 // pre-mRNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202190_at NM_001324 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001324.1 /DEF=Homo sapiens cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kD (CSTF1), mRNA. /FEA=mRNA /GEN=CSTF1 /PROD=cleavage stimulation factor subunit 1 /DB_XREF=gi:4557490 /UG=Hs.172865 cleavage stimulation factor, 3 pre-RNA, subunit 1, 50kD /FL=gb:BC001011.1 gb:L02547.1 gb:NM_001324.1" NM_001324 "cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa" CSTF1 1477 NM_001033521 /// NM_001033522 /// NM_001324 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006379 // mRNA cleavage // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202191_s_at BE439987 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE439987 /FEA=EST /DB_XREF=gi:9439470 /DB_XREF=est:HTM1-745F /UG=Hs.226133 growth arrest-specific 7 /FL=gb:AB007854.1 gb:NM_005890.1 BE439987 growth arrest-specific 7 GAS7 8522 NM_001130831 /// NM_003644 /// NM_201432 /// NM_201433 /// XM_005256831 /// XM_005256832 /// XM_005256833 /// XM_005256834 /// XM_005256835 "0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation" 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 202192_s_at NM_005890 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005890.1 /DEF=Homo sapiens growth arrest-specific 7 (GAS7), transcript variant b, mRNA. /FEA=mRNA /GEN=GAS7 /PROD=growth arrest-specific 7 isoform b /DB_XREF=gi:5360211 /UG=Hs.226133 growth arrest-specific 7 /FL=gb:AB007854.1 gb:NM_005890.1" NM_005890 growth arrest-specific 7 GAS7 8522 NM_001130831 /// NM_003644 /// NM_201432 /// NM_201433 /// XM_005256831 /// XM_005256832 /// XM_005256833 /// XM_005256834 /// XM_005256835 "0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from electronic annotation" 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 202193_at NM_005569 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005569.2 /DEF=Homo sapiens LIM domain kinase 2 (LIMK2), transcript variant 2a, mRNA. /FEA=mRNA /GEN=LIMK2 /PROD=LIM domain kinase 2 isoform 2a /DB_XREF=gi:8051619 /UG=Hs.278027 LIM domain kinase 2 /FL=gb:D45906.1 gb:NM_005569.2" NM_005569 LIM domain kinase 2 LIMK2 3985 NM_001031801 /// NM_005569 /// NM_016733 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // traceable author statement /// 0042325 // regulation of phosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005801 // cis-Golgi network // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation" 202194_at AL117354 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL117354 /DEF=Human DNA sequence from clone RP5-976O13 on chromosome 1p21.2-22.2 Contains part of the gene for CGI-100 protein, 3 isoforms of the gene for M96 protein, ESTs, STSs, GSSs and a CpG Island /FEA=mRNA_1 /DB_XREF=gi:6822199 /UG=Hs.296155 CGI-100 protein /FL=gb:AF151858.1 gb:NM_016040.1" AL117354 transmembrane emp24 protein transport domain containing 5 TMED5 50999 NM_001167830 /// NM_016040 /// NR_030761 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0090161 // Golgi ribbon formation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202195_s_at NM_016040 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016040.1 /DEF=Homo sapiens CGI-100 protein (LOC50999), mRNA. /FEA=mRNA /GEN=LOC50999 /PROD=CGI-100 protein /DB_XREF=gi:7705583 /UG=Hs.296155 CGI-100 protein /FL=gb:AF151858.1 gb:NM_016040.1" NM_016040 transmembrane emp24 protein transport domain containing 5 TMED5 50999 NM_001167830 /// NM_016040 /// NR_030761 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0090161 // Golgi ribbon formation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070971 // endoplasmic reticulum exit site // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202196_s_at NM_013253 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013253.1 /DEF=Homo sapiens dickkopf (Xenopus laevis) homolog 3 (DKK3), mRNA. /FEA=mRNA /GEN=DKK3 /PROD=Dickkopf gene 3 /DB_XREF=gi:7019362 /UG=Hs.4909 dickkopf (Xenopus laevis) homolog 3 /FL=gb:AF177396.1 gb:AB033421.1 gb:AB034203.1 gb:NM_013253.1" NM_013253 dickkopf WNT signaling pathway inhibitor 3 DKK3 27122 NM_001018057 /// NM_013253 /// NM_015881 /// XM_006718177 /// XM_006718178 /// XM_006718179 /// XM_006718180 "0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from expression pattern /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay" 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 202197_at NM_021090 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021090.1 /DEF=Homo sapiens myotubularin related protein 3 (MTMR3), mRNA. /FEA=mRNA /GEN=MTMR3 /PROD=myotubularin related protein 3 /DB_XREF=gi:10835108 /UG=Hs.63302 myotubularin related protein 3 /FL=gb:NM_021090.1 gb:AB002369.1 gb:AF233438.1" NM_021090 myotubularin related protein 3 MTMR3 8897 NM_001013676 /// NM_021090 /// NM_153050 /// NM_153051 /// XM_005261803 /// XM_005261804 /// XM_005261805 /// XM_005261806 /// XM_005261807 /// XM_005261808 /// XM_005261809 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202198_s_at AF233438 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF233438.1 /DEF=Homo sapiens FYVE domain-containing dual specificity protein phosphatase FYVE-DSP1c mRNA, complete cds. /FEA=mRNA /PROD=FYVE domain-containing dual specificity proteinphosphatase FYVE-DSP1c /DB_XREF=gi:7208447 /UG=Hs.63302 myotubularin related protein 3 /FL=gb:NM_021090.1 gb:AB002369.1 gb:AF233438.1" AF233438 myotubularin related protein 3 MTMR3 8897 NM_001013676 /// NM_021090 /// NM_153050 /// NM_153051 /// XM_005261803 /// XM_005261804 /// XM_005261805 /// XM_005261806 /// XM_005261807 /// XM_005261808 /// XM_005261809 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202199_s_at AW082913 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW082913 /FEA=EST /DB_XREF=gi:6038065 /DB_XREF=est:xc04c12.x1 /CLONE=IMAGE:2583286 /UG=Hs.75761 SFRS protein kinase 1 /FL=gb:NM_003137.1 gb:U09564.1 AW082913 SRSF protein kinase 1 SRPK1 6732 NM_003137 /// NR_034069 "0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007059 // chromosome segregation // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035092 // sperm chromatin condensation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement /// 0050684 // regulation of mRNA processing // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202200_s_at NM_003137 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003137.1 /DEF=Homo sapiens SFRS protein kinase 1 (SRPK1), mRNA. /FEA=mRNA /GEN=SRPK1 /PROD=SFRS protein kinase 1 /DB_XREF=gi:4507218 /UG=Hs.75761 SFRS protein kinase 1 /FL=gb:NM_003137.1 gb:U09564.1" NM_003137 SRSF protein kinase 1 SRPK1 6732 NM_003137 /// NR_034069 "0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007059 // chromosome segregation // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035092 // sperm chromatin condensation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement /// 0050684 // regulation of mRNA processing // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202201_at NM_000713 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000713.1 /DEF=Homo sapiens biliverdin reductase B (flavin reductase (NADPH)) (BLVRB), mRNA. /FEA=mRNA /GEN=BLVRB /PROD=biliverdin reductase B (flavin reductase(NADPH)) /DB_XREF=gi:4502418 /UG=Hs.76289 biliverdin reductase B (flavin reductase (NADPH)) /FL=gb:D26308.1 gb:NM_000713.1" NM_000713 biliverdin reductase B (flavin reductase (NADPH)) BLVRB 645 NM_000713 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // inferred from direct assay /// 0042167 // heme catabolic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0004074 // biliverdin reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042602 // riboflavin reductase (NADPH) activity // inferred from direct assay /// 0050662 // coenzyme binding // inferred from electronic annotation" 202202_s_at NM_002290 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002290.2 /DEF=Homo sapiens laminin, alpha 4 (LAMA4), mRNA. /FEA=mRNA /GEN=LAMA4 /PROD=laminin, alpha 4 precursor /DB_XREF=gi:9845494 /UG=Hs.78672 laminin, alpha 4 /FL=gb:NM_002290.2" NM_002290 "laminin, alpha 4" LAMA4 3910 NM_001105206 /// NM_001105207 /// NM_001105208 /// NM_001105209 /// NM_002290 /// XM_005266983 /// XM_005266984 /// XM_006715480 /// XM_006715481 0001568 // blood vessel development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005605 // basal lamina // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202203_s_at NM_001144 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001144.1 /DEF=Homo sapiens autocrine motility factor receptor (AMFR), mRNA. /FEA=mRNA /GEN=AMFR /PROD=autocrine motility factor receptor /DB_XREF=gi:4502074 /UG=Hs.80731 autocrine motility factor receptor /FL=gb:NM_001144.1 gb:L35233.1 gb:AF124145.1" NM_001144 "autocrine motility factor receptor, E3 ubiquitin protein ligase" AMFR 267 NM_001144 /// NM_138958 /// XM_005255889 /// XM_005255890 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202204_s_at AF124145 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF124145.1 /DEF=Homo sapiens autocrine motility factor receptor (AMFR) mRNA, complete cds. /FEA=mRNA /GEN=AMFR /PROD=autocrine motility factor receptor /DB_XREF=gi:5931954 /UG=Hs.80731 autocrine motility factor receptor /FL=gb:NM_001144.1 gb:L35233.1 gb:AF124145.1" AF124145 "autocrine motility factor receptor, E3 ubiquitin protein ligase" AMFR 267 NM_001144 /// NM_138958 /// XM_005255889 /// XM_005255890 0000209 // protein polyubiquitination // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0051259 // protein oligomerization // inferred from direct assay 0000836 // Hrd1p ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202205_at NM_003370 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003370.1 /DEF=Homo sapiens vasodilator-stimulated phosphoprotein (VASP), mRNA. /FEA=mRNA /GEN=VASP /PROD=vasodilator-stimulated phosphoprotein /DB_XREF=gi:4507868 /UG=Hs.93183 vasodilator-stimulated phosphoprotein /FL=gb:NM_003370.1" NM_003370 vasodilator-stimulated phosphoprotein VASP 7408 NM_001008736 /// NM_003370 /// XM_005259199 /// XM_005259200 0001843 // neural tube closure // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0034329 // cell junction assembly // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 202206_at AW450363 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW450363 /FEA=EST /DB_XREF=gi:6991139 /DB_XREF=est:UI-H-BI3-akn-d-02-0-UI.s1 /CLONE=IMAGE:2734875 /UG=Hs.111554 ADP-ribosylation factor-like 7 /FL=gb:BC001051.1 gb:AB016811.1 gb:NM_005737.2 AW450363 ADP-ribosylation factor-like 4C ARL4C 10123 NM_001282431 /// NM_005737 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 202207_at BG435404 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG435404 /FEA=EST /DB_XREF=gi:13341910 /DB_XREF=est:602507678F1 /CLONE=IMAGE:4605066 /UG=Hs.111554 ADP-ribosylation factor-like 7 /FL=gb:BC001051.1 gb:AB016811.1 gb:NM_005737.2 BG435404 ADP-ribosylation factor-like 4C ARL4C 10123 NM_001282431 /// NM_005737 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 202208_s_at BC001051 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001051.1 /DEF=Homo sapiens, ADP-ribosylation factor-like 7, clone MGC:1575, mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor-like 7 /DB_XREF=gi:12654450 /UG=Hs.111554 ADP-ribosylation factor-like 7 /FL=gb:BC001051.1 gb:AB016811.1 gb:NM_005737.2" BC001051 ADP-ribosylation factor-like 4C ARL4C 10123 NM_001282431 /// NM_005737 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032456 // endocytic recycling // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from direct assay 202209_at NM_014463 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014463.1 /DEF=Homo sapiens Lsm3 protein (LSM3), mRNA. /FEA=mRNA /GEN=LSM3 /PROD=Lsm3 protein /DB_XREF=gi:7657314 /UG=Hs.111632 Lsm3 protein /FL=gb:AF182418.1 gb:AF182289.1 gb:NM_014463.1" NM_014463 "LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)" LSM3 27258 NM_014463 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202210_x_at NM_019884 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019884.1 /DEF=Homo sapiens glycogen synthase kinase 3 alpha (GSK3A), mRNA. /FEA=mRNA /GEN=GSK3A /PROD=glycogen synthase kinase 3 alpha /DB_XREF=gi:11995473 /UG=Hs.118890 glycogen synthase kinase 3 alpha /FL=gb:NM_019884.1 gb:D63424.1 gb:L40027.1" NM_019884 glycogen synthase kinase 3 alpha GSK3A 2931 NM_019884 0003073 // regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010905 // negative regulation of UDP-glucose catabolic process // inferred by curator /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032007 // negative regulation of TOR signaling // inferred from sequence or structural similarity /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0036016 // cellular response to interleukin-3 // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // traceable author statement /// 0045732 // positive regulation of protein catabolic process // non-traceable author statement /// 0045823 // positive regulation of heart contraction // inferred from sequence or structural similarity /// 0046325 // negative regulation of glucose import // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051348 // negative regulation of transferase activity // inferred from mutant phenotype /// 0061052 // negative regulation of cell growth involved in cardiac muscle cell development // inferred from sequence or structural similarity /// 0071879 // positive regulation of adrenergic receptor signaling pathway // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from sequence or structural similarity /// 2000077 // negative regulation of type B pancreatic cell development // traceable author statement /// 2000466 // negative regulation of glycogen (starch) synthase activity // traceable author statement /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity 0005829 // cytosol // traceable author statement /// 0030877 // beta-catenin destruction complex // non-traceable author statement /// 0030877 // beta-catenin destruction complex // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0050321 // tau-protein kinase activity // traceable author statement" 202211_at BC005122 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005122.1 /DEF=Homo sapiens, ADP-ribosylation factor GTPase activating protein 1, clone MGC:10272, mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor GTPase activatingprotein 1 /DB_XREF=gi:13477296 /UG=Hs.13014 ADP-ribosylation factor GTPase activating protein 1 /FL=gb:BC005122.1 gb:AF111847.1 gb:NM_014570.1" BC005122 ADP-ribosylation factor GTPase activating protein 3 ARFGAP3 26286 NM_001142293 /// NM_014570 /// XM_005261525 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0009306 // protein secretion // inferred from expression pattern /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202212_at NM_014303 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014303.1 /DEF=Homo sapiens pescadillo (zebrafish) homolog 1, containing BRCT domain (PES1), mRNA. /FEA=mRNA /GEN=PES1 /PROD=pescadillo (zebrafish) homolog 1, containingBRCT domain /DB_XREF=gi:7657454 /UG=Hs.13501 pescadillo (zebrafish) homolog 1, containing BRCT domain /FL=gb:U78310.1 gb:NM_014303.1" NM_014303 pescadillo ribosomal biogenesis factor 1 PES1 23481 NM_001243225 /// NM_001282327 /// NM_001282328 /// NM_014303 /// XM_006724173 "0000463 // maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0000466 // maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0007000 // nucleolus organization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008283 // cell proliferation // non-traceable author statement /// 0033365 // protein localization to organelle // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042273 // ribosomal large subunit biogenesis // inferred by curator /// 0051726 // regulation of cell cycle // inferred from mutant phenotype" "0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030687 // preribosome, large subunit precursor // inferred from direct assay /// 0070545 // PeBoW complex // inferred from direct assay" 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202213_s_at AI650819 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI650819 /FEA=EST /DB_XREF=gi:4734798 /DB_XREF=est:wa95a10.x1 /CLONE=IMAGE:2303898 /UG=Hs.155976 cullin 4B /FL=gb:NM_003588.1 gb:AB014595.1 AI650819 cullin 4B CUL4B 8450 NM_001079872 /// NM_003588 /// XM_005262481 /// XM_006724784 /// XM_006724785 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from direct assay /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 202214_s_at NM_003588 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003588.1 /DEF=Homo sapiens cullin 4B (CUL4B), mRNA. /FEA=mRNA /GEN=CUL4B /PROD=cullin 4B /DB_XREF=gi:13270466 /UG=Hs.155976 cullin 4B /FL=gb:NM_003588.1 gb:AB014595.1" NM_003588 cullin 4B CUL4B 8450 NM_001079872 /// NM_003588 /// XM_005262481 /// XM_006724784 /// XM_006724785 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0070914 // UV-damage excision repair // inferred from direct assay /// 1900087 // positive regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003684 // damaged DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 202215_s_at NM_014223 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014223.2 /DEF=Homo sapiens nuclear transcription factor Y, gamma (NFYC), mRNA. /FEA=mRNA /GEN=NFYC /PROD=nuclear transcription factor Y, gamma /DB_XREF=gi:11496977 /UG=Hs.168157 nuclear transcription factor Y, gamma /FL=gb:NM_014223.2 gb:D85425.1 gb:BC005003.1 gb:D89986.1" NM_014223 "nuclear transcription factor Y, gamma" NFYC 4802 NM_001142587 /// NM_001142588 /// NM_001142589 /// NM_001142590 /// NM_014223 /// XM_005270891 /// XM_005270893 /// XM_005270894 /// XM_005270895 /// XM_005270896 /// XM_006710656 /// XM_006710657 /// XM_006710658 /// XM_006710659 /// XM_006710660 /// XM_006710661 /// XM_006710662 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202216_x_at BC005003 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005003.1 /DEF=Homo sapiens, nuclear transcription factor Y, gamma, clone MGC:792, mRNA, complete cds. /FEA=mRNA /PROD=nuclear transcription factor Y, gamma /DB_XREF=gi:13436472 /UG=Hs.168157 nuclear transcription factor Y, gamma /FL=gb:NM_014223.2 gb:D85425.1 gb:BC005003.1 gb:D89986.1" BC005003 "nuclear transcription factor Y, gamma" NFYC 4802 NM_001142587 /// NM_001142588 /// NM_001142589 /// NM_001142590 /// NM_014223 /// XM_005270891 /// XM_005270893 /// XM_005270894 /// XM_005270895 /// XM_005270896 /// XM_006710656 /// XM_006710657 /// XM_006710658 /// XM_006710659 /// XM_006710660 /// XM_006710661 /// XM_006710662 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202217_at NM_004649 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004649.1 /DEF=Homo sapiens ES1 (zebrafish) protein, human homolog of (C21ORF33), mRNA. /FEA=mRNA /GEN=C21ORF33 /PROD=ES1 (zebrafish) protein, human homolog of /DB_XREF=gi:5031690 /UG=Hs.182423 ES1 (zebrafish) protein, human homolog of /FL=gb:BC002370.1 gb:BC003587.1 gb:D86061.1 gb:U53003.1 gb:NM_004649.1" NM_004649 chromosome 21 open reading frame 33 C21orf33 8209 NM_004649 /// NM_198155 /// XM_005261184 /// XM_005261185 /// XM_005261186 /// XM_006724055 /// XM_006724056 0005739 // mitochondrion // not recorded 202218_s_at NM_004265 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004265.1 /DEF=Homo sapiens delta-6 fatty acid desaturase (FADSD6), mRNA. /FEA=mRNA /GEN=FADSD6 /PROD=delta-6 fatty acid desaturase /DB_XREF=gi:4758333 /UG=Hs.184641 fatty acid desaturase 2 /FL=gb:AF084559.1 gb:AF126799.1 gb:NM_004265.1" NM_004265 fatty acid desaturase 2 FADS2 9415 NM_001281501 /// NM_001281502 /// NM_004265 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // inferred from electronic annotation /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0043651 // linoleic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation "0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation" 202219_at NM_005629 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005629.1 /DEF=Homo sapiens solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), mRNA. /FEA=mRNA /GEN=SLC6A8 /PROD=solute carrier family 6 (neurotransmittertransporter, creatine), member 8 /DB_XREF=gi:5032096 /UG=Hs.187958 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 /FL=gb:L31409.1 gb:NM_005629.1" NM_005629 "solute carrier family 6 (neurotransmitter transporter), member 8" SLC6A8 6535 NM_001142805 /// NM_001142806 /// NM_005629 0006600 // creatine metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0015871 // choline transport // inferred from electronic annotation /// 0015881 // creatine transport // non-traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // inferred from electronic annotation /// 1902598 // creatine transmembrane transport // non-traceable author statement /// 1902598 // creatine transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0005308 // creatine transmembrane transporter activity // non-traceable author statement /// 0005309 // creatine:sodium symporter activity // inferred from electronic annotation /// 0005328 // neurotransmitter:sodium symporter activity // inferred from electronic annotation /// 0015220 // choline transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 202220_at NM_014949 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014949.1 /DEF=Homo sapiens KIAA0907 protein (KIAA0907), mRNA. /FEA=mRNA /GEN=KIAA0907 /PROD=KIAA0907 protein /DB_XREF=gi:7662371 /UG=Hs.24656 KIAA0907 protein /FL=gb:AB020714.1 gb:NM_014949.1" NM_014949 KIAA0907 KIAA0907 22889 NM_014949 0003723 // RNA binding // inferred from electronic annotation 202221_s_at AV727101 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV727101 /FEA=EST /DB_XREF=gi:10836522 /DB_XREF=est:AV727101 /CLONE=HTCBGF05 /UG=Hs.25272 E1A binding protein p300 /FL=gb:NM_001429.1 gb:U01877.1 AV727101 E1A binding protein p300 EP300 2033 NM_001429 /// XM_006724165 "0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0001666 // response to hypoxia // inferred from direct assay /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006475 // internal protein amino acid acetylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0031324 // negative regulation of cellular metabolic process // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from mutant phenotype /// 0043969 // histone H2B acetylation // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement /// 0060177 // regulation of angiotensin metabolic process // inferred from electronic annotation /// 0060298 // positive regulation of sarcomere organization // inferred from electronic annotation /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // traceable author statement /// 0090043 // regulation of tubulin deacetylation // inferred from direct assay" 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000940 // condensed chromosome outer kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from electronic annotation "0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from direct assay /// 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001159 // core promoter proximal region DNA binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003823 // antigen binding // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0042975 // peroxisome proliferator activated receptor binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation" 202222_s_at NM_001927 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001927.1 /DEF=Homo sapiens desmin (DES), mRNA. /FEA=mRNA /GEN=DES /PROD=desmin /DB_XREF=gi:4503306 /UG=Hs.279604 desmin /FL=gb:AF167579.1 gb:U59167.1 gb:AF055081.1 gb:AF055082.1 gb:AF055083.1 gb:NM_001927.1 gb:AF137053.1" NM_001927 desmin DES 1674 NM_001927 0006936 // muscle contraction // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0008016 // regulation of heart contraction // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043292 // contractile fiber // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202223_at NM_002219 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002219.1 /DEF=Homo sapiens integral membrane protein 1 (ITM1), mRNA. /FEA=mRNA /GEN=ITM1 /PROD=integral membrane protein 1 /DB_XREF=gi:4504786 /UG=Hs.287850 integral membrane protein 1 /FL=gb:NM_002219.1 gb:L38961.1" NM_002219 "STT3A, subunit of the oligosaccharyltransferase complex (catalytic)" STT3A 3703 NM_001278503 /// NM_001278504 /// NM_152713 0006486 // protein glycosylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // inferred from sequence or structural similarity /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043686 // co-translational protein modification // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0004576 // oligosaccharyl transferase activity // inferred from electronic annotation /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from mutant phenotype /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation" 202224_at BF304695 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF304695 /FEA=EST /DB_XREF=gi:11251580 /DB_XREF=est:601888248F1 /CLONE=IMAGE:4122466 /UG=Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog /FL=gb:D10656.1 gb:NM_016823.1 BF304695 v-crk avian sarcoma virus CT10 oncogene homolog CRK 1398 NM_005206 /// NM_016823 0000186 // activation of MAPKK activity // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction" 202225_at AW612311 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW612311 /FEA=EST /DB_XREF=gi:7317497 /DB_XREF=est:hg95e07.x1 /CLONE=IMAGE:2953380 /UG=Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog /FL=gb:D10656.1 gb:NM_016823.1 AW612311 v-crk avian sarcoma virus CT10 oncogene homolog CRK 1398 NM_005206 /// NM_016823 0000186 // activation of MAPKK activity // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction" 202226_s_at NM_016823 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016823.1 /DEF=Homo sapiens v-crk avian sarcoma virus CT10 oncogene homolog (CRK), transcript variant II, mRNA. /FEA=mRNA /GEN=CRK /PROD=v-crk avian sarcoma virus CT10 oncogene homologisoform a /DB_XREF=gi:8400705 /UG=Hs.306088 v-crk avian sarcoma virus CT10 oncogene homolog /FL=gb:D10656.1 gb:NM_016823.1" NM_016823 v-crk avian sarcoma virus CT10 oncogene homolog CRK 1398 NM_005206 /// NM_016823 0000186 // activation of MAPKK activity // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred by curator /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from physical interaction /// 0045309 // protein phosphorylated amino acid binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from physical interaction" 202227_s_at NM_006696 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006696.1 /DEF=Homo sapiens thyroid hormone receptor coactivating protein (SMAP), mRNA. /FEA=mRNA /GEN=SMAP /PROD=thyroid hormone receptor coactivating protein /DB_XREF=gi:5730052 /UG=Hs.5464 thyroid hormone receptor coactivating protein /FL=gb:AF016270.1 gb:NM_006696.1" NM_006696 bromodomain containing 8 BRD8 10902 NM_001164326 /// NM_006696 /// NM_139199 /// NM_183359 /// XM_005271855 /// XM_005271856 /// XM_005271857 /// XM_005271859 /// XM_005271860 /// XM_005271861 /// XM_005271864 /// XM_005271865 /// XM_006714524 /// XM_006714525 /// XR_427701 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay" 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202228_s_at NM_017455 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017455.1 /DEF=Homo sapiens stromal cell derived factor receptor 1 (SDFR1), transcript variant alpha, mRNA. /FEA=mRNA /GEN=SDFR1 /PROD=stromal cell derived factor receptor 1 isoforma /DB_XREF=gi:9257239 /UG=Hs.6354 stromal cell derived factor receptor 1 /FL=gb:AF109127.1 gb:NM_017455.1" NM_017455 neuroplastin NPTN 27020 NM_001161363 /// NM_001161364 /// NM_012428 /// NM_017455 /// XM_005254304 /// XR_429449 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity 0005105 // type 1 fibroblast growth factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 202229_s_at AI372979 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI372979 /FEA=EST /DB_XREF=gi:4152845 /DB_XREF=est:qz17g05.x1 /CLONE=IMAGE:2021816 /UG=Hs.6430 protein with polyglutamine repeat; calcium (ca2+) homeostasis endoplasmic reticulum protein /FL=gb:U94836.2 gb:NM_006387.2 AI372979 calcium homeostasis endoplasmic reticulum protein CHERP 10523 NM_006387 0006396 // RNA processing // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051533 // positive regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202230_s_at NM_006387 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006387.2 /DEF=Homo sapiens protein with polyglutamine repeat; calcium (ca2+) homeostasis endoplasmic reticulum protein (ERPROT213-21), mRNA. /FEA=mRNA /GEN=ERPROT213-21 /PROD=protein with polyglutamine repeat; calcium(ca2+) homeostasis endoplasmic reticulum protein /DB_XREF=gi:11055968 /UG=Hs.6430 protein with polyglutamine repeat; calcium (ca2+) homeostasis endoplasmic reticulum protein /FL=gb:U94836.2 gb:NM_006387.2" NM_006387 calcium homeostasis endoplasmic reticulum protein CHERP 10523 NM_006387 0006396 // RNA processing // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051533 // positive regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202231_at NM_006360 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006360.1 /DEF=Homo sapiens dendritic cell protein (GA17), mRNA. /FEA=mRNA /GEN=GA17 /PROD=dendritic cell protein /DB_XREF=gi:5453653 /UG=Hs.69469 dendritic cell protein /FL=gb:AF277183.1 gb:AF064603.1 gb:NM_006360.1" NM_006360 "eukaryotic translation initiation factor 3, subunit M" EIF3M 10480 NM_006360 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0002183 // cytoplasmic translational initiation // not recorded /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred by curator /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 202232_s_at NM_006360 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006360.1 /DEF=Homo sapiens dendritic cell protein (GA17), mRNA. /FEA=mRNA /GEN=GA17 /PROD=dendritic cell protein /DB_XREF=gi:5453653 /UG=Hs.69469 dendritic cell protein /FL=gb:AF277183.1 gb:AF064603.1 gb:NM_006360.1" NM_006360 "eukaryotic translation initiation factor 3, subunit M" EIF3M 10480 NM_006360 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0002183 // cytoplasmic translational initiation // not recorded /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred by curator /// 0006446 // regulation of translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation 0003743 // translation initiation factor activity // inferred by curator /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202233_s_at NM_006004 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006004.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase hinge protein (UQCRH), mRNA. /FEA=mRNA /GEN=UQCRH /PROD=ubiquinol-cytochrome c reductase hinge protein /DB_XREF=gi:5174744 /UG=Hs.73818 ubiquinol-cytochrome c reductase hinge protein /FL=gb:BC001426.1 gb:BC001934.1 gb:M36647.1 gb:NM_006004.1" NM_006004 ubiquinol-cytochrome c reductase hinge protein /// ubiquinol-cytochrome c reductase hinge protein-like UQCRH /// UQCRHL 7388 /// 440567 NM_001089591 /// NM_006004 /// XM_005271167 "0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006119 // oxidative phosphorylation // traceable author statement /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // not recorded /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // not recorded /// 0007266 // Rho protein signal transduction // /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030168 // platelet activation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031584 // activation of phospholipase D activity // not recorded /// 0031584 // activation of phospholipase D activity // /// 0031584 // activation of phospholipase D activity // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0005750 // mitochondrial respiratory chain complex III // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005834 // heterotrimeric G-protein complex // /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031526 // brush border membrane // not recorded /// 0031526 // brush border membrane // /// 0031526 // brush border membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // /// 0003924 // GTPase activity // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0004871 // signal transducer activity // /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031683 // G-protein beta/gamma-subunit complex binding // /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // not recorded /// 0031702 // type 1 angiotensin receptor binding // /// 0031752 // D5 dopamine receptor binding // not recorded /// 0031752 // D5 dopamine receptor binding // /// 0031752 // D5 dopamine receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202234_s_at BF511091 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF511091 /FEA=EST /DB_XREF=gi:11594389 /DB_XREF=est:UI-H-BI4-apn-c-05-0-UI.s1 /CLONE=IMAGE:3087753 /UG=Hs.75231 solute carrier family 16 (monocarboxylic acid transporters), member 1 /FL=gb:NM_003051.1 gb:L31801.1" BF511091 "solute carrier family 16 (monocarboxylate transporter), member 1" SLC16A1 6566 NM_001166496 /// NM_003051 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0015728 // mevalonate transport // traceable author statement /// 0035873 // lactate transmembrane transport // inferred from electronic annotation /// 0035879 // plasma membrane lactate transport // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015130 // mevalonate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097159 // organic cyclic compound binding // inferred from electronic annotation 202235_at BF511091 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF511091 /FEA=EST /DB_XREF=gi:11594389 /DB_XREF=est:UI-H-BI4-apn-c-05-0-UI.s1 /CLONE=IMAGE:3087753 /UG=Hs.75231 solute carrier family 16 (monocarboxylic acid transporters), member 1 /FL=gb:NM_003051.1 gb:L31801.1" BF511091 "solute carrier family 16 (monocarboxylate transporter), member 1" SLC16A1 6566 NM_001166496 /// NM_003051 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0015728 // mevalonate transport // traceable author statement /// 0035873 // lactate transmembrane transport // inferred from electronic annotation /// 0035879 // plasma membrane lactate transport // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015130 // mevalonate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097159 // organic cyclic compound binding // inferred from electronic annotation 202236_s_at NM_003051 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003051.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 1 (SLC16A1), mRNA. /FEA=mRNA /GEN=SLC16A1 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 1 /DB_XREF=gi:4506982 /UG=Hs.75231 solute carrier family 16 (monocarboxylic acid transporters), member 1 /FL=gb:NM_003051.1 gb:L31801.1" NM_003051 "solute carrier family 16 (monocarboxylate transporter), member 1" SLC16A1 6566 NM_001166496 /// NM_003051 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0015728 // mevalonate transport // traceable author statement /// 0035873 // lactate transmembrane transport // inferred from electronic annotation /// 0035879 // plasma membrane lactate transport // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015130 // mevalonate transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097159 // organic cyclic compound binding // inferred from electronic annotation 202237_at NM_006169 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006169.1 /DEF=Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA. /FEA=mRNA /GEN=NNMT /PROD=nicotinamide N-methyltransferase /DB_XREF=gi:5453789 /UG=Hs.76669 nicotinamide N-methyltransferase /FL=gb:BC000234.1 gb:U08021.1 gb:NM_006169.1" NM_006169 uncharacterized LOC101928916 /// nicotinamide N-methyltransferase LOC101928916 /// NNMT 4837 /// 101928916 NM_006169 /// XR_246479 /// XR_247717 /// XR_252975 0006805 // xenobiotic metabolic process // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0008112 // nicotinamide N-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202238_s_at NM_006169 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006169.1 /DEF=Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA. /FEA=mRNA /GEN=NNMT /PROD=nicotinamide N-methyltransferase /DB_XREF=gi:5453789 /UG=Hs.76669 nicotinamide N-methyltransferase /FL=gb:BC000234.1 gb:U08021.1 gb:NM_006169.1" NM_006169 uncharacterized LOC101928916 /// nicotinamide N-methyltransferase LOC101928916 /// NNMT 4837 /// 101928916 NM_006169 /// XR_246479 /// XR_247717 /// XR_252975 0006805 // xenobiotic metabolic process // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0008112 // nicotinamide N-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202239_at NM_006437 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006437.2 /DEF=Homo sapiens ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1 (ADPRTL1), mRNA. /FEA=mRNA /GEN=ADPRTL1 /PROD=poly(ADP-ribosyl)transferase-like 1 /DB_XREF=gi:11496990 /UG=Hs.77225 ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1 /FL=gb:NM_006437.2 gb:AF057160.1 gb:AF158255.1" NM_006437 "poly (ADP-ribose) polymerase family, member 4" PARP4 143 NM_006437 0006281 // DNA repair // non-traceable author statement /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006471 // protein ADP-ribosylation // non-traceable author statement /// 0006810 // transport // non-traceable author statement /// 0006954 // inflammatory response // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // non-traceable author statement /// 0008219 // cell death // inferred from mutant phenotype /// 0042493 // response to drug // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003677 // DNA binding // traceable author statement /// 0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0003950 // NAD+ ADP-ribosyltransferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay" 202240_at NM_005030 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005030.1 /DEF=Homo sapiens polo (Drosophia)-like kinase (PLK), mRNA. /FEA=mRNA /GEN=PLK /PROD=polo (Drosophia)-like kinase /DB_XREF=gi:4826915 /UG=Hs.77597 polo (Drosophia)-like kinase /FL=gb:BC002369.1 gb:BC003002.1 gb:U01038.1 gb:L19559.1 gb:NM_005030.1" NM_005030 polo-like kinase 1 PLK1 5347 NM_005030 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0000281 // mitotic cytokinesis // inferred from direct assay /// 0000910 // cytokinesis // inferred from direct assay /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0001578 // microtubule bundle formation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from mutant phenotype /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // traceable author statement /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0008283 // cell proliferation // traceable author statement /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0031648 // protein destabilization // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0040038 // polar body extrusion after meiotic divisions // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0045184 // establishment of protein localization // inferred from mutant phenotype /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // traceable author statement /// 0071168 // protein localization to chromatin // inferred from direct assay "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from direct assay /// 0000942 // condensed nuclear chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay" "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from mutant phenotype /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction" 202241_at NM_025195 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_025195.1 /DEF=Homo sapiens phosphoprotein regulated by mitogenic pathways (C8FW), mRNA. /FEA=mRNA /GEN=C8FW /PROD=G-protein-coupled receptor induced protein /DB_XREF=gi:13399327 /UG=Hs.7837 phosphoprotein regulated by mitogenic pathways /FL=gb:AF205437.1 gb:NM_025195.1" NM_025195 tribbles pseudokinase 1 TRIB1 10221 NM_001282985 /// NM_025195 /// XM_006716496 /// XM_006716497 /// XR_428373 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007254 // JNK cascade // inferred from mutant phenotype /// 0014912 // negative regulation of smooth muscle cell migration // inferred from mutant phenotype /// 0031665 // negative regulation of lipopolysaccharide-mediated signaling pathway // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0043405 // regulation of MAP kinase activity // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0004672 // protein kinase activity // traceable author statement /// 0004860 // protein kinase inhibitor activity // inferred from mutant phenotype /// 0005524 // ATP binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0055106 // ubiquitin-protein transferase regulator activity // inferred from sequence or structural similarity" 202242_at NM_004615 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004615.1 /DEF=Homo sapiens transmembrane 4 superfamily member 2 (TM4SF2), mRNA. /FEA=mRNA /GEN=TM4SF2 /PROD=transmembrane 4 superfamily member 2 /DB_XREF=gi:4759235 /UG=Hs.82749 transmembrane 4 superfamily member 2 /FL=gb:D10653.1 gb:D29808.1 gb:NM_004615.1" NM_004615 tetraspanin 7 TSPAN7 7102 NM_004615 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202243_s_at NM_002796 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002796.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4), mRNA. /FEA=mRNA /GEN=PSMB4 /PROD=proteasome (prosome, macropain) subunit, betatype, 4 /DB_XREF=gi:4506198 /UG=Hs.89545 proteasome (prosome, macropain) subunit, beta type, 4 /FL=gb:BC000331.1 gb:NM_002796.1 gb:D26600.1" NM_002796 "proteasome (prosome, macropain) subunit, beta type, 4" PSMB4 5692 NM_002796 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202244_at NM_002796 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002796.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4), mRNA. /FEA=mRNA /GEN=PSMB4 /PROD=proteasome (prosome, macropain) subunit, betatype, 4 /DB_XREF=gi:4506198 /UG=Hs.89545 proteasome (prosome, macropain) subunit, beta type, 4 /FL=gb:BC000331.1 gb:NM_002796.1 gb:D26600.1" NM_002796 "proteasome (prosome, macropain) subunit, beta type, 4" PSMB4 5692 NM_002796 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001530 // lipopolysaccharide binding // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202245_at AW084510 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW084510 /FEA=EST /DB_XREF=gi:6039662 /DB_XREF=est:wz24g11.x1 /CLONE=IMAGE:2559044 /UG=Hs.93199 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) /FL=gb:NM_002340.1 gb:U22526.1" AW084510 "lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)" LSS 4047 NM_001001438 /// NM_001145436 /// NM_001145437 /// NM_002340 /// XM_006724003 /// XM_006724004 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000250 // lanosterol synthase activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation 202246_s_at NM_000075 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000075.1 /DEF=Homo sapiens cyclin-dependent kinase 4 (CDK4), mRNA. /FEA=mRNA /GEN=CDK4 /PROD=cyclin-dependent kinase 4 /DB_XREF=gi:4502734 /UG=Hs.95577 cyclin-dependent kinase 4 /FL=gb:BC003644.1 gb:U79269.1 gb:NM_000075.1 gb:M14505.1" NM_000075 cyclin-dependent kinase 4 CDK4 1019 NM_000075 /// NM_052984 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from genetic interaction /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045793 // positive regulation of cell size // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation" 202247_s_at BE561596 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE561596 /FEA=EST /DB_XREF=gi:9805316 /DB_XREF=est:601347512F1 /CLONE=IMAGE:3688347 /UG=Hs.101448 metastasis associated 1 /FL=gb:U35113.1 gb:NM_004689.1 BE561596 metastasis associated 1 MTA1 9112 NM_001203258 /// NM_004689 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0033363 // secretory granule organization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202248_at BC000110 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000110.1 /DEF=Homo sapiens, Similar to E2F transcription factor 5, clone MGC:1262, mRNA, complete cds. /FEA=mRNA /PROD=Similar to E2F transcription factor 5 /DB_XREF=gi:12652720 /UG=Hs.108371 E2F transcription factor 4, p107p130-binding /FL=gb:BC000110.1 gb:NM_001950.2 gb:U15641.1" BC000110 "E2F transcription factor 4, p107/p130-binding" E2F4 1874 NM_001950 "0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0002064 // epithelial cell development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008015 // blood circulation // inferred from electronic annotation /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202249_s_at AU146233 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU146233 /FEA=EST /DB_XREF=gi:11007754 /DB_XREF=est:AU146233 /CLONE=HEMBA1007223 /UG=Hs.110707 H326 /FL=gb:U06631.1 gb:NM_015726.1 AU146233 DDB1 and CUL4 associated factor 8 DCAF8 50717 NM_015726 /// NR_028103 /// NR_028104 /// NR_028105 /// NR_028106 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202250_s_at NM_015726 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015726.1 /DEF=Homo sapiens H326 (H326), mRNA. /FEA=mRNA /GEN=H326 /PROD=H326 /DB_XREF=gi:7657147 /UG=Hs.110707 H326 /FL=gb:U06631.1 gb:NM_015726.1" NM_015726 DDB1 and CUL4 associated factor 8 DCAF8 50717 NM_015726 /// NR_028103 /// NR_028104 /// NR_028105 /// NR_028106 0016567 // protein ubiquitination // inferred by curator /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005777 // peroxisome // inferred from electronic annotation /// 0080008 // Cul4-RING E3 ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202251_at NM_004698 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004698.1 /DEF=Homo sapiens U4U6-associated RNA splicing factor (HPRP3P), mRNA. /FEA=mRNA /GEN=HPRP3P /PROD=U4U6-associated RNA splicing factor /DB_XREF=gi:4758555 /UG=Hs.11776 U4U6-associated RNA splicing factor /FL=gb:BC000184.1 gb:BC001954.1 gb:AF016370.1 gb:AF001947.1 gb:NM_004698.1" NM_004698 pre-mRNA processing factor 3 PRPF3 9129 NM_004698 /// XR_241103 /// XR_241104 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // non-traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202252_at NM_002870 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002870.1 /DEF=Homo sapiens RAB13, member RAS oncogene family (RAB13), mRNA. /FEA=mRNA /GEN=RAB13 /PROD=RAB13, member RAS oncogene family /DB_XREF=gi:4506362 /UG=Hs.151536 RAB13, member RAS oncogene family /FL=gb:BC000799.1 gb:NM_002870.1" NM_002870 "RAB13, member RAS oncogene family" RAB13 5872 NM_001272038 /// NM_002870 /// NR_073553 0006184 // GTP catabolic process // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010737 // protein kinase A signaling // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0032456 // endocytic recycling // inferred from mutant phenotype /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0035767 // endothelial cell chemotaxis // inferred from sequence or structural similarity /// 0044795 // trans-Golgi network to recycling endosome transport // inferred from sequence or structural similarity /// 0061024 // membrane organization // traceable author statement /// 0070830 // tight junction assembly // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0097368 // establishment of Sertoli cell barrier // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0032593 // insulin-responsive compartment // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from electronic annotation 202253_s_at NM_004945 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004945.1 /DEF=Homo sapiens dynamin 2 (DNM2), mRNA. /FEA=mRNA /GEN=DNM2 /PROD=dynamin 2 /DB_XREF=gi:4826699 /UG=Hs.167013 dynamin 2 /FL=gb:L36983.1 gb:NM_004945.1" NM_004945 dynamin 2 DNM2 1785 NM_001005360 /// NM_001005361 /// NM_001005362 /// NM_001190716 /// NM_004945 "0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // non-traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0033572 // transferrin transport // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0048489 // synaptic vesicle transport // non-traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0061024 // membrane organization // traceable author statement" 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from direct assay /// 0045334 // clathrin-coated endocytic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 202254_at AB007900 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB007900.1 /DEF=Homo sapiens KIAA0440 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0440 /DB_XREF=gi:2662160 /UG=Hs.172180 KIAA0440 protein /FL=gb:AF090990.1 gb:NM_015556.1" AB007900 signal-induced proliferation-associated 1 like 1 SIPA1L1 26037 NM_001284245 /// NM_001284246 /// NM_001284247 /// NM_015556 /// XM_005267514 /// XM_005267516 /// XM_005267519 /// XM_006720109 /// XM_006720110 /// XM_006720111 /// XM_006720112 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032317 // regulation of Rap GTPase activity // inferred from sequence or structural similarity /// 0032861 // activation of Rap GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from electronic annotation 202255_s_at NM_015556 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015556.1 /DEF=Homo sapiens KIAA0440 protein (KIAA0440), mRNA. /FEA=mRNA /GEN=KIAA0440 /PROD=KIAA0440 protein /DB_XREF=gi:7662125 /UG=Hs.172180 KIAA0440 protein /FL=gb:AF090990.1 gb:NM_015556.1" NM_015556 signal-induced proliferation-associated 1 like 1 SIPA1L1 26037 NM_001284245 /// NM_001284246 /// NM_001284247 /// NM_015556 /// XM_005267514 /// XM_005267516 /// XM_005267519 /// XM_006720109 /// XM_006720110 /// XM_006720111 /// XM_006720112 0031532 // actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 0032317 // regulation of Rap GTPase activity // inferred from sequence or structural similarity /// 0032861 // activation of Rap GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046875 // ephrin receptor binding // inferred from electronic annotation 202256_at BF793888 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF793888 /FEA=EST /DB_XREF=gi:12098942 /DB_XREF=est:602255284F1 /CLONE=IMAGE:4347332 /UG=Hs.202677 CD2 antigen (cytoplasmic tail)-binding protein 2 /FL=gb:BC000495.1 gb:BC001947.1 gb:AF104222.1 gb:NM_006110.1 BF793888 CD2 (cytoplasmic tail) binding protein 2 CD2BP2 10421 NM_001243646 /// NM_006110 "0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 202257_s_at NM_006110 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006110.1 /DEF=Homo sapiens CD2 antigen (cytoplasmic tail)-binding protein 2 (CD2BP2), mRNA. /FEA=mRNA /GEN=CD2BP2 /PROD=CD2 antigen (cytoplasmic tail)-binding protein2 /DB_XREF=gi:5174408 /UG=Hs.202677 CD2 antigen (cytoplasmic tail)-binding protein 2 /FL=gb:BC000495.1 gb:BC001947.1 gb:AF104222.1 gb:NM_006110.1" NM_006110 CD2 (cytoplasmic tail) binding protein 2 CD2BP2 10421 NM_001243646 /// NM_006110 "0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005682 // U5 snRNP // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 202258_s_at U50532 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:U50532.1 /DEF=Human BRCA2 region, mRNA sequence CG005. /FEA=mRNA /PROD=unknown /DB_XREF=gi:1531603 /UG=Hs.23518 hypothetical protein from BCRA2 region /FL=gb:NM_014887.1" U50532 NEDD4 binding protein 2-like 2 N4BP2L2 10443 NM_001278432 /// NM_014887 /// NM_033111 /// XM_005266218 /// XM_005266219 /// XM_005266220 /// XM_005266221 /// XM_005266222 /// XM_005266223 /// XM_005266224 /// XM_005266228 /// XM_006719754 /// XR_429211 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 1902035 // positive regulation of hematopoietic stem cell proliferation // inferred from mutant phenotype /// 1902037 // negative regulation of hematopoietic stem cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 202259_s_at NM_014887 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014887.1 /DEF=Homo sapiens hypothetical protein from BCRA2 region (CG005), mRNA. /FEA=mRNA /GEN=CG005 /PROD=hypothetical protein from BCRA2 region /DB_XREF=gi:7656970 /UG=Hs.23518 hypothetical protein from BCRA2 region /FL=gb:NM_014887.1" NM_014887 NEDD4 binding protein 2-like 2 N4BP2L2 10443 NM_001278432 /// NM_014887 /// NM_033111 /// XM_005266218 /// XM_005266219 /// XM_005266220 /// XM_005266221 /// XM_005266222 /// XM_005266223 /// XM_005266224 /// XM_005266228 /// XM_006719754 /// XR_429211 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 1902035 // positive regulation of hematopoietic stem cell proliferation // inferred from mutant phenotype /// 1902037 // negative regulation of hematopoietic stem cell differentiation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001106 // RNA polymerase II transcription corepressor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 202260_s_at NM_003165 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003165.1 /DEF=Homo sapiens syntaxin binding protein 1 (STXBP1), mRNA. /FEA=mRNA /GEN=STXBP1 /PROD=syntaxin binding protein 1 /DB_XREF=gi:4507296 /UG=Hs.239356 syntaxin binding protein 1 /FL=gb:AF004563.1 gb:NM_003165.1" NM_003165 syntaxin binding protein 1 STXBP1 6812 NM_001032221 /// NM_003165 "0002576 // platelet degranulation // inferred from mutant phenotype /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007412 // axon target recognition // inferred from sequence or structural similarity /// 0010807 // regulation of synaptic vesicle priming // inferred from sequence or structural similarity /// 0014047 // glutamate secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0032229 // negative regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050821 // protein stabilization // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0070527 // platelet aggregation // inferred from mutant phenotype" 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0031091 // platelet alpha granule // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from sequence or structural similarity /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation 202261_at NM_005997 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005997.1 /DEF=Homo sapiens transcription factor-like 1 (TCFL1), mRNA. /FEA=mRNA /GEN=TCFL1 /PROD=transcription factor-like 1 /DB_XREF=gi:5174714 /UG=Hs.2430 transcription factor-like 1 /FL=gb:BC003151.1 gb:NM_005997.1 gb:D43642.1" NM_005997 vacuolar protein sorting 72 homolog (S. cerevisiae) VPS72 6944 NM_001271087 /// NM_001271088 /// NM_005997 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202262_x_at NM_013974 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013974.1 /DEF=Homo sapiens dimethylarginine dimethylaminohydrolase 2 (DDAH2), mRNA. /FEA=mRNA /GEN=DDAH2 /PROD=dimethylarginine dimethylaminohydrolase 2 /DB_XREF=gi:7524353 /UG=Hs.247362 dimethylarginine dimethylaminohydrolase 2 /FL=gb:BC001435.1 gb:AF070667.1 gb:NM_013974.1" NM_013974 dimethylarginine dimethylaminohydrolase 2 DDAH2 23564 NM_013974 /// XM_005248974 /// XM_005272783 /// XM_005274929 /// XM_005275086 /// XM_005275225 /// XM_005275361 /// XM_005275522 0000052 // citrulline metabolic process // inferred from direct assay /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006527 // arginine catabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016403 // dimethylargininase activity // inferred from direct assay /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation" 202263_at NM_016243 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016243.1 /DEF=Homo sapiens cytochrome b5 reductase 1 (B5R.1) (LOC51706), mRNA. /FEA=mRNA /GEN=LOC51706 /PROD=cytochrome b5 reductase 1 (B5R.1) /DB_XREF=gi:7706454 /UG=Hs.289113 cytochrome b5 reductase 1 (B5R.1) /FL=gb:AF169481.1 gb:AF125533.1 gb:NM_016243.1" NM_016243 cytochrome b5 reductase 1 CYB5R1 51706 NM_016243 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation" 202264_s_at NM_006114 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006114.1 /DEF=Homo sapiens DNA segment on chromosome 19 (unique) 1177 expressed sequence (D19S1177E), mRNA. /FEA=mRNA /GEN=D19S1177E /PROD=mitochondrial outer membrane protein TOM40 /DB_XREF=gi:5174722 /UG=Hs.30928 DNA segment on chromosome 19 (unique) 1177 expressed sequence /FL=gb:BC001779.1 gb:AF043250.1 gb:NM_006114.1" NM_006114 translocase of outer mitochondrial membrane 40 homolog (yeast) TOMM40 10452 NM_001128916 /// NM_001128917 /// NM_006114 /// XM_005258411 0006626 // protein targeting to mitochondrion // inferred from mutant phenotype /// 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071806 // protein transmembrane transport // inferred from sequence or structural similarity /// 0071806 // protein transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from mutant phenotype /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0032592 // integral component of mitochondrial membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008320 // protein transmembrane transporter activity // inferred from sequence or structural similarity /// 0008320 // protein transmembrane transporter activity // traceable author statement /// 0015288 // porin activity // inferred from electronic annotation 202265_at NM_005180 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005180.1 /DEF=Homo sapiens murine leukemia viral (bmi-1) oncogene homolog (BMI1), mRNA. /FEA=mRNA /GEN=BMI1 /PROD=murine leukemia viral (bmi-1) oncogene homolog /DB_XREF=gi:4885094 /UG=Hs.431 murine leukemia viral (bmi-1) oncogene homolog /FL=gb:L13689.1 gb:NM_005180.1" NM_005180 "BMI1 proto-oncogene, polycomb ring finger /// COMMD3-BMI1 readthrough" BMI1 /// COMMD3-BMI1 648 /// 100532731 NM_001204062 /// NM_005180 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007379 // segment specification // traceable author statement /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from expression pattern /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from direct assay" 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071535 // RING-like zinc finger domain binding // inferred from physical interaction 202266_at NM_016614 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016614.1 /DEF=Homo sapiens TRAF and TNF receptor-associated protein (AD022), mRNA. /FEA=mRNA /GEN=AD022 /PROD=TRAF and TNF receptor-associated protein /DB_XREF=gi:7705261 /UG=Hs.46847 TRAF and TNF receptor-associated protein /FL=gb:AF201687.1 gb:AF223469.1 gb:NM_016614.1" NM_016614 tyrosyl-DNA phosphodiesterase 2 TDP2 51567 NM_016614 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // traceable author statement /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0036317 // tyrosyl-RNA phosphodiesterase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070260 // 5'-tyrosyl-DNA phosphodiesterase activity // inferred from direct assay /// 0070260 // 5'-tyrosyl-DNA phosphodiesterase activity // inferred from mutant phenotype 202267_at NM_005562 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005562.1 /DEF=Homo sapiens laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa)) (LAMC2), transcript variant 1, mRNA. /FEA=mRNA /GEN=LAMC2 /PROD=laminin, gamma 2, isoform a precursor /DB_XREF=gi:5031846 /UG=Hs.54451 laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa)) /FL=gb:NM_005562.1" NM_005562 "laminin, gamma 2" LAMC2 3918 NM_005562 /// NM_018891 /// XM_005245150 /// XM_006711316 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005607 // laminin-2 complex // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 202268_s_at NM_003905 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003905.1 /DEF=Homo sapiens amyloid beta precursor protein-binding protein 1, 59kD (APPBP1), mRNA. /FEA=mRNA /GEN=APPBP1 /PROD=Amyloid beta precursor protein-binding protein1 /DB_XREF=gi:4502168 /UG=Hs.61828 amyloid beta precursor protein-binding protein 1, 59kD /FL=gb:AL136798.1 gb:BC000480.1 gb:U50939.1 gb:NM_003905.1" NM_003905 NEDD8 activating enzyme E1 subunit 1 NAE1 8883 NM_001018159 /// NM_001018160 /// NM_001286500 /// NM_003905 /// XM_005256215 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0033314 // mitotic DNA replication checkpoint // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from direct assay /// 0043523 // regulation of neuron apoptotic process // inferred from direct assay /// 0045116 // protein neddylation // inferred from direct assay /// 0045116 // protein neddylation // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from direct assay 0005634 // nucleus // not recorded /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019781 // NEDD8 activating enzyme activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 202269_x_at BC002666 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002666.1 /DEF=Homo sapiens, guanylate binding protein 1, interferon-inducible, 67kD, clone MGC:3949, mRNA, complete cds. /FEA=mRNA /PROD=guanylate binding protein 1,interferon-inducible, 67kD /DB_XREF=gi:12803662 /UG=Hs.62661 guanylate binding protein 1, interferon-inducible, 67kD /FL=gb:BC002666.1 gb:M55542.1 gb:NM_002053.1" BC002666 "guanylate binding protein 1, interferon-inducible" GBP1 2633 NM_002053 /// XM_006710573 0002376 // immune system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202270_at NM_002053 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002053.1 /DEF=Homo sapiens guanylate binding protein 1, interferon-inducible, 67kD (GBP1), mRNA. /FEA=mRNA /GEN=GBP1 /PROD=guanylate binding protein 1,interferon-inducible, 67kD /DB_XREF=gi:4503938 /UG=Hs.62661 guanylate binding protein 1, interferon-inducible, 67kD /FL=gb:BC002666.1 gb:M55542.1 gb:NM_002053.1" NM_002053 "guanylate binding protein 1, interferon-inducible" GBP1 2633 NM_002053 /// XM_006710573 0002376 // immune system process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202271_at AB007952 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB007952.1 /DEF=Homo sapiens mRNA for KIAA0483 protein, partial cds. /FEA=mRNA /GEN=KIAA0483 /PROD=KIAA0483 protein /DB_XREF=gi:3413925 /UG=Hs.64691 KIAA0483 protein /FL=gb:NM_015176.1" AB007952 F-box protein 28 FBXO28 23219 NM_001136115 /// NM_015176 /// NR_049764 0005515 // protein binding // inferred from electronic annotation 202272_s_at NM_015176 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015176.1 /DEF=Homo sapiens KIAA0483 protein (KIAA0483), mRNA. /FEA=mRNA /GEN=KIAA0483 /PROD=KIAA0483 protein /DB_XREF=gi:7662157 /UG=Hs.64691 KIAA0483 protein /FL=gb:NM_015176.1" NM_015176 F-box protein 28 FBXO28 23219 NM_001136115 /// NM_015176 /// NR_049764 0005515 // protein binding // inferred from electronic annotation 202273_at NM_002609 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002609.1 /DEF=Homo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB), mRNA. /FEA=mRNA /GEN=PDGFRB /PROD=platelet-derived growth factor receptor, betapolypeptide /DB_XREF=gi:4505682 /UG=Hs.76144 platelet-derived growth factor receptor, beta polypeptide /FL=gb:M21616.1 gb:J03278.1 gb:NM_002609.1" NM_002609 "platelet-derived growth factor receptor, beta polypeptide" PDGFRB 5159 NM_002609 /// XM_005268464 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0006024 // glycosaminoglycan biosynthetic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from mutant phenotype /// 0014911 // positive regulation of smooth muscle cell migration // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from sequence or structural similarity /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from electronic annotation /// 0035441 // cell migration involved in vasculogenesis // inferred from sequence or structural similarity /// 0035789 // metanephric mesenchymal cell migration // inferred from electronic annotation /// 0035791 // platelet-derived growth factor receptor-beta signaling pathway // inferred from mutant phenotype /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity /// 0035909 // aorta morphogenesis // inferred from sequence or structural similarity /// 0036120 // cellular response to platelet-derived growth factor stimulus // traceable author statement /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045840 // positive regulation of mitosis // inferred from sequence or structural similarity /// 0046488 // phosphatidylinositol metabolic process // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060981 // cell migration involved in coronary angiogenesis // inferred from sequence or structural similarity /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071670 // smooth muscle cell chemotaxis // inferred from sequence or structural similarity /// 0072075 // metanephric mesenchyme development // inferred from electronic annotation /// 0072262 // metanephric glomerular mesangial cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072275 // metanephric glomerulus morphogenesis // inferred from electronic annotation /// 0072277 // metanephric glomerular capillary formation // inferred from sequence or structural similarity /// 0072278 // metanephric comma-shaped body morphogenesis // inferred from electronic annotation /// 0072284 // metanephric S-shaped body morphogenesis // inferred from electronic annotation /// 0090280 // positive regulation of calcium ion import // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity /// 2000573 // positive regulation of DNA biosynthetic process // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005764 // lysosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004992 // platelet activating factor receptor activity // traceable author statement /// 0005017 // platelet-derived growth factor-activated receptor activity // traceable author statement /// 0005019 // platelet-derived growth factor beta-receptor activity // inferred from direct assay /// 0005019 // platelet-derived growth factor beta-receptor activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from physical interaction /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction" 202274_at NM_001615 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001615.2 /DEF=Homo sapiens actin, gamma 2, smooth muscle, enteric (ACTG2), mRNA. /FEA=mRNA /GEN=ACTG2 /PROD=actin, gamma 2 propeptide /DB_XREF=gi:11038625 /UG=Hs.78045 actin, gamma 2, smooth muscle, enteric /FL=gb:NM_001615.2" NM_001615 "actin, gamma 2, smooth muscle, enteric" ACTG2 72 NM_001199893 /// NM_001615 0006936 // muscle contraction // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0014829 // vascular smooth muscle contraction // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030485 // smooth muscle contractile fiber // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 202275_at NM_000402 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000402.1 /DEF=Homo sapiens glucose-6-phosphate dehydrogenase (G6PD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=G6PD /PROD=glucose-6-phosphate dehydrogenase /DB_XREF=gi:4503844 /UG=Hs.80206 glucose-6-phosphate dehydrogenase /FL=gb:BC000337.1 gb:M21248.1 gb:NM_000402.1" NM_000402 glucose-6-phosphate dehydrogenase G6PD 2539 NM_000402 /// NM_001042351 /// XM_005274657 /// XM_005274658 "0001816 // cytokine production // inferred from mutant phenotype /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // inferred from direct assay /// 0006098 // pentose-phosphate shunt // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006739 // NADP metabolic process // inferred from direct assay /// 0006740 // NADPH regeneration // inferred from mutant phenotype /// 0006749 // glutathione metabolic process // inferred from mutant phenotype /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from mutant phenotype /// 0010734 // negative regulation of protein glutathionylation // inferred from mutant phenotype /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019322 // pentose biosynthetic process // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032094 // response to food // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0043249 // erythrocyte maturation // inferred from mutant phenotype /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046390 // ribose phosphate biosynthetic process // inferred from mutant phenotype /// 0051156 // glucose 6-phosphate metabolic process // inferred from direct assay /// 0051156 // glucose 6-phosphate metabolic process // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from mutant phenotype" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from direct assay /// 0004345 // glucose-6-phosphate dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005536 // glucose binding // inferred from direct assay /// 0005536 // glucose binding // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050661 // NADP binding // inferred from direct assay 202276_at NM_006304 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006304.1 /DEF=Homo sapiens Deleted in split-handsplit-foot 1 region (DSS1), mRNA. /FEA=mRNA /GEN=DSS1 /PROD=deleted in split-handsplit-foot 1 region /DB_XREF=gi:5453639 /UG=Hs.85215 Deleted in split-handsplit-foot 1 region /FL=gb:U41515.1 gb:NM_006304.1" NM_006304 split hand/foot malformation (ectrodactyly) type 1 SHFM1 7979 NM_006304 0000724 // double-strand break repair via homologous recombination // not recorded /// 0006508 // proteolysis // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay 202277_at AL568804 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL568804 /FEA=EST /DB_XREF=gi:12923509 /DB_XREF=est:AL568804 /CLONE=CS0DE005YN15 (3 prime) /UG=Hs.90458 serine palmitoyltransferase, long chain base subunit 1 /FL=gb:NM_006415.1" AL568804 "serine palmitoyltransferase, long chain base subunit 1" SPTLC1 10558 NM_001281303 /// NM_006415 /// NM_178324 /// XR_242563 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay /// 0035339 // SPOTS complex // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation" 202278_s_at NM_006415 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006415.1 /DEF=Homo sapiens serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), mRNA. /FEA=mRNA /GEN=SPTLC1 /PROD=serine palmitoyltransferase, long chain basesubunit 1 /DB_XREF=gi:5454083 /UG=Hs.90458 serine palmitoyltransferase, long chain base subunit 1 /FL=gb:NM_006415.1" NM_006415 "serine palmitoyltransferase, long chain base subunit 1" SPTLC1 10558 NM_001281303 /// NM_006415 /// NM_178324 /// XR_242563 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay /// 0035339 // SPOTS complex // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation" 202279_at NM_004894 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004894.1 /DEF=Homo sapiens chromosome 14 open reading frame 2 (C14ORF2), mRNA. /FEA=mRNA /GEN=C14ORF2 /PROD=chromosome 14 open reading frame 2 /DB_XREF=gi:4758939 /UG=Hs.109052 chromosome 14 open reading frame 2 /FL=gb:BC000429.1 gb:BC001944.1 gb:AF054175.1 gb:NM_004894.1" NM_004894 chromosome 14 open reading frame 2 C14orf2 9556 NM_001127393 /// NM_004894 0005739 // mitochondrion // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 202280_at D88435 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:D88435.1 /DEF=Homo sapiens mRNA for HsGAK, complete cds. /FEA=mRNA /PROD=HsGAK /DB_XREF=gi:2506079 /UG=Hs.153227 cyclin G associated kinase /FL=gb:D88435.1 gb:NM_005255.1" D88435 202281_at NM_005255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005255.1 /DEF=Homo sapiens cyclin G associated kinase (GAK), mRNA. /FEA=mRNA /GEN=GAK /PROD=cyclin G associated kinase /DB_XREF=gi:4885250 /UG=Hs.153227 cyclin G associated kinase /FL=gb:D88435.1 gb:NM_005255.1" NM_005255 cyclin G associated kinase GAK 2580 NM_001286833 /// NM_005255 /// XM_005272268 /// XM_005272269 /// XM_005272270 /// XM_005272272 /// XM_005272273 /// XM_006713874 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202282_at NM_004493 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004493.1 /DEF=Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase, type II (HADH2), mRNA. /FEA=mRNA /GEN=HADH2 /PROD=hydroxyacyl-Coenzyme A dehydrogenase, type II /DB_XREF=gi:4758503 /UG=Hs.171280 hydroxyacyl-Coenzyme A dehydrogenase, type II /FL=gb:BC000372.1 gb:BC000829.1 gb:U73514.1 gb:U96132.1 gb:AF035555.1 gb:AF069134.1 gb:NM_004493.1" NM_004493 hydroxysteroid (17-beta) dehydrogenase 10 HSD17B10 3028 NM_001037811 /// NM_004493 0006629 // lipid metabolic process // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008709 // cholate 7-alpha-dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030283 // testosterone dehydrogenase [NAD(P)] activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047015 // 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity // inferred from electronic annotation 202283_at NM_002615 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002615.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (SERPINF1), mRNA. /FEA=mRNA /GEN=SERPINF1 /PROD=serine (or cysteine) proteinase inhibitor, cladeF (alpha-2 antiplasmin, pigment epithelium derivedfactor), member 1 /DB_XREF=gi:4505708 /UG=Hs.173594 serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 /FL=gb:M90439.1 gb:BC000522.1 gb:M76979.1 gb:NM_002615.1" NM_002615 "serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1" SERPINF1 5176 NM_002615 0001822 // kidney development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007614 // short-term memory // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0030162 // regulation of proteolysis // not recorded /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050769 // positive regulation of neurogenesis // inferred from direct assay /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded 202284_s_at NM_000389 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000389.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), mRNA. /FEA=mRNA /GEN=CDKN1A /PROD=cyclin-dependent kinase inhibitor 1A (p21,Cip1) /DB_XREF=gi:11386202 /UG=Hs.179665 cyclin-dependent kinase inhibitor 1A (p21, Cip1) /FL=gb:NM_000389.1 gb:BC000275.1 gb:BC001935.1 gb:U03106.1 gb:L26165.1 gb:L25610.1 gb:U09579.1" NM_000389 "cyclin-dependent kinase inhibitor 1A (p21, Cip1)" CDKN1A 1026 NM_000389 /// NM_001220777 /// NM_001220778 /// NM_001291549 /// NM_078467 "0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007346 // regulation of mitotic cell cycle // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from expression pattern /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from mutant phenotype /// 0033158 // regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043068 // positive regulation of programmed cell death // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0055093 // response to hyperoxia // inferred from electronic annotation /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0071850 // mitotic cell cycle arrest // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype /// 0090400 // stress-induced premature senescence // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2000278 // regulation of DNA biosynthetic process // inferred from electronic annotation /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype" 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070557 // PCNA-p21 complex // inferred from direct assay 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019912 // cyclin-dependent protein kinase activating kinase activity // inferred from direct assay /// 0030332 // cyclin binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202285_s_at AI627697 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI627697 /FEA=EST /DB_XREF=gi:4664497 /DB_XREF=est:ty81g09.x1 /CLONE=IMAGE:2285536 /UG=Hs.23582 tumor-associated calcium signal transducer 2 /FL=gb:NM_002353.1 AI627697 tumor-associated calcium signal transducer 2 TACSTD2 4070 NM_002353 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202286_s_at J04152 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:J04152 /DEF=Human gastrointestinal tumor-associated antigen GA733-1 protein gene, complete cds, clone 05516 /FEA=mRNA /DB_XREF=gi:182893 /UG=Hs.23582 tumor-associated calcium signal transducer 2 /FL=gb:NM_002353.1" J04152 tumor-associated calcium signal transducer 2 TACSTD2 4070 NM_002353 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004672 // protein kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation 202287_s_at NM_002353 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002353.1 /DEF=Homo sapiens tumor-associated calcium signal transducer 2 (TACSTD2), mRNA. /FEA=mRNA /GEN=TACSTD2 /PROD=tumor-associated calcium signal transducer 2precursor /DB_XREF=gi:4505056 /UG=Hs.23582 tumor-associated calcium signal transducer 2 /FL=gb:NM_002353.1" NM_002353 tumor-associated calcium signal transducer 2 TACSTD2 4070 NM_002353 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202288_at U88966 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U88966.1 /DEF=Human protein rapamycin associated protein (FRAP2) gene, complete cds. /FEA=mRNA /GEN=FRAP2 /PROD=rapamycin associated protein FRAP2 /DB_XREF=gi:3282238 /UG=Hs.250723 FK506 binding protein 12-rapamycin associated protein 1 /FL=gb:U88966.1 gb:NM_004958.1 gb:L34075.1" U88966 mechanistic target of rapamycin (serine/threonine kinase) MTOR 2475 NM_004958 /// XM_005263438 /// XM_005263439 /// XR_244786 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0005979 // regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0006109 // regulation of carbohydrate metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0006950 // response to stress // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007584 // response to nutrient // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010507 // negative regulation of autophagy // inferred from sequence or structural similarity /// 0010592 // positive regulation of lamellipodium assembly // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0016049 // cell growth // inferred from direct assay /// 0016049 // cell growth // traceable author statement /// 0016242 // negative regulation of macroautophagy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from direct assay /// 0018105 // peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0030163 // protein catabolic process // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031529 // ruffle organization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from sequence or structural similarity /// 0031929 // TOR signaling // inferred from mutant phenotype /// 0031998 // regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0032095 // regulation of response to food // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040007 // growth // non-traceable author statement /// 0043200 // response to amino acid // inferred from direct assay /// 0043610 // regulation of carbohydrate utilization // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045792 // negative regulation of cell size // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from sequence or structural similarity 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // non-traceable author statement /// 0012505 // endomembrane system // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016605 // PML body // inferred from sequence or structural similarity /// 0031931 // TORC1 complex // inferred from direct assay /// 0031931 // TORC1 complex // inferred from mutant phenotype /// 0031932 // TORC2 complex // inferred from direct assay /// 0070438 // mTOR-FKBP12-rapamycin complex // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0001030 // RNA polymerase III type 1 promoter DNA binding // inferred from direct assay /// 0001031 // RNA polymerase III type 2 promoter DNA binding // inferred from direct assay /// 0001032 // RNA polymerase III type 3 promoter DNA binding // inferred from direct assay /// 0001156 // TFIIIC-class transcription factor binding // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from physical interaction" 202289_s_at NM_006997 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006997.1 /DEF=Homo sapiens transforming, acidic coiled-coil containing protein 2 (TACC2), mRNA. /FEA=mRNA /GEN=TACC2 /PROD=transforming, acidic coiled-coil containingprotein 2 /DB_XREF=gi:11119413 /UG=Hs.272023 transforming, acidic coiled-coil containing protein 2 /FL=gb:AF095791.2 gb:NM_006997.1" NM_006997 "transforming, acidic coiled-coil containing protein 2" TACC2 10579 NM_001291876 /// NM_001291877 /// NM_001291878 /// NM_001291879 /// NM_006997 /// NM_206860 /// NM_206861 /// NM_206862 /// XM_005269388 /// XM_005269389 /// XM_005269390 /// XM_005269391 /// XM_005269392 /// XM_005269393 /// XM_005269394 /// XM_005269395 /// XM_005269396 /// XM_005269397 /// XM_005269399 /// XM_006717548 /// XM_006717549 /// XM_006717550 /// XM_006717551 /// XM_006717552 /// XM_006717553 /// XM_006717554 /// XM_006717555 /// XM_006717556 /// XM_006717557 /// XM_006717558 /// XM_006717559 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0030953 // astral microtubule organization // inferred from electronic annotation /// 0032886 // regulation of microtubule-based process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from direct assay 202290_at NM_014891 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014891.1 /DEF=Homo sapiens PDGF associated protein (HASPP28), mRNA. /FEA=mRNA /GEN=HASPP28 /PROD=PDGF associated protein /DB_XREF=gi:7657440 /UG=Hs.278426 PDGFA associated protein 1 /FL=gb:U41745.1 gb:BC000684.1 gb:NM_014891.1" NM_014891 PDGFA associated protein 1 PDAP1 11333 NM_014891 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 202291_s_at NM_000900 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000900.1 /DEF=Homo sapiens matrix Gla protein (MGP), mRNA. /FEA=mRNA /GEN=MGP /PROD=matrix Gla protein /DB_XREF=gi:4505178 /UG=Hs.279009 matrix Gla protein /FL=gb:M58549.1 gb:NM_000900.1" NM_000900 matrix Gla protein MGP 4256 NM_000900 /// NM_001190839 0001502 // cartilage condensation // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030500 // regulation of bone mineralization // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008147 // structural constituent of bone // traceable author statement 202292_x_at NM_007260 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007260.1 /DEF=Homo sapiens lysophospholipase II (LYPLA2), mRNA. /FEA=mRNA /GEN=LYPLA2 /PROD=lysophospholipase II /DB_XREF=gi:9966763 /UG=Hs.283655 lysophospholipase II /FL=gb:AF098668.1 gb:NM_007260.1" NM_007260 lysophospholipase II LYPLA2 11313 NM_007260 /// XM_005245728 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation 202293_at AW168948 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW168948 /FEA=EST /DB_XREF=gi:6400473 /DB_XREF=est:xj15f07.x1 /CLONE=IMAGE:2657317 /UG=Hs.286148 stromal antigen 1 /FL=gb:NM_005862.1 AW168948 stromal antigen 1 STAG1 10274 NM_005862 /// XM_006713471 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation "0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from direct assay" 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202294_at AI126490 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI126490 /FEA=EST /DB_XREF=gi:3595004 /DB_XREF=est:qd82h04.x1 /CLONE=IMAGE:1736023 /UG=Hs.286148 stromal antigen 1 /FL=gb:NM_005862.1 AI126490 stromal antigen 1 STAG1 10274 NM_005862 /// XM_006713471 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation "0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030054 // cell junction // inferred from direct assay" 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202295_s_at NM_004390 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004390.1 /DEF=Homo sapiens cathepsin H (CTSH), mRNA. /FEA=mRNA /GEN=CTSH /PROD=cathepsin H /DB_XREF=gi:4758095 /UG=Hs.288181 cathepsin H /FL=gb:BC002479.1 gb:NM_004390.1" NM_004390 cathepsin H CTSH 1512 NM_004390 /// NM_148979 /// XM_005254181 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001913 // T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002764 // immune response-regulating signaling pathway // inferred from direct assay /// 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010634 // positive regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0010813 // neuropeptide catabolic process // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010952 // positive regulation of peptidase activity // inferred from direct assay /// 0019882 // antigen processing and presentation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031638 // zymogen activation // inferred from direct assay /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from sequence or structural similarity /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043129 // surfactant homeostasis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0060448 // dichotomous subdivision of terminal units involved in lung branching // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0001520 // outer dense fiber // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004177 // aminopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030108 // HLA-A specific activating MHC class I receptor activity // inferred from direct assay /// 0030984 // kininogen binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay 202296_s_at NM_007033 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007033.1 /DEF=Homo sapiens similar to S. cerevisiae RER1 (RER1), mRNA. /FEA=mRNA /GEN=RER1 /PROD=similar to S. cerevisiae RER1 /DB_XREF=gi:5902045 /UG=Hs.40500 similar to S. cerevisiae RER1 /FL=gb:BC004965.1 gb:NM_007033.1 gb:AF157324.1" NM_007033 retention in endoplasmic reticulum sorting receptor 1 RER1 11079 NM_007033 /// XM_005244713 /// XM_006710305 /// XM_006710306 /// XM_006710307 "0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from direct assay" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 202297_s_at AF157324 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF157324.1 /DEF=Homo sapiens RER1 protein (RER1) mRNA, complete cds. /FEA=mRNA /GEN=RER1 /PROD=RER1 protein /DB_XREF=gi:7688698 /UG=Hs.40500 similar to S. cerevisiae RER1 /FL=gb:BC004965.1 gb:NM_007033.1 gb:AF157324.1" AF157324 retention in endoplasmic reticulum sorting receptor 1 RER1 11079 NM_007033 /// XM_005244713 /// XM_006710305 /// XM_006710306 /// XM_006710307 "0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from direct assay" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 202298_at NM_004541 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004541.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) (NDUFA1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NDUFA1 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 1 /DB_XREF=gi:13699820 /UG=Hs.74823 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) /FL=gb:BC000266.1 gb:NM_004541.2 gb:U54993.1" NM_004541 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa" NDUFA1 4694 NM_004541 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202299_s_at NM_006402 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006402.1 /DEF=Homo sapiens hepatitis B virus x-interacting protein (9.6kD) (XIP), mRNA. /FEA=mRNA /GEN=XIP /PROD=hepatitis B virus x-interacting protein /DB_XREF=gi:5454169 /UG=Hs.80464 hepatitis B virus x-interacting protein (9.6kD) /FL=gb:AF029890.1 gb:NM_006402.1" NM_006402 "late endosomal/lysosomal adaptor, MAPK and MTOR activator 5" LAMTOR5 10542 NM_006402 0008361 // regulation of cell size // inferred from mutant phenotype /// 0009615 // response to virus // traceable author statement /// 0019079 // viral genome replication // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0061462 // protein localization to lysosome // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0071986 // Ragulator complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 202300_at NM_006402 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006402.1 /DEF=Homo sapiens hepatitis B virus x-interacting protein (9.6kD) (XIP), mRNA. /FEA=mRNA /GEN=XIP /PROD=hepatitis B virus x-interacting protein /DB_XREF=gi:5454169 /UG=Hs.80464 hepatitis B virus x-interacting protein (9.6kD) /FL=gb:AF029890.1 gb:NM_006402.1" NM_006402 "late endosomal/lysosomal adaptor, MAPK and MTOR activator 5" LAMTOR5 10542 NM_006402 0008361 // regulation of cell size // inferred from mutant phenotype /// 0009615 // response to virus // traceable author statement /// 0019079 // viral genome replication // inferred from electronic annotation /// 0032008 // positive regulation of TOR signaling // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0061462 // protein localization to lysosome // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0071986 // Ragulator complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 202301_s_at BE396879 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE396879 /FEA=EST /DB_XREF=gi:9342244 /DB_XREF=est:601289401F1 /CLONE=IMAGE:3619848 /UG=Hs.81648 hypothetical protein FLJ11021 similar to splicing factor, arginineserine-rich 4 /FL=gb:NM_023012.1" BE396879 arginine/serine-rich coiled-coil 2 RSRC2 65117 NM_023012 /// NM_198261 /// NM_198262 /// NR_036434 /// NR_036435 /// NR_036436 /// XM_005253601 /// XM_005253602 /// XM_005253604 /// XM_005253606 /// XR_242958 /// XR_242959 0044822 // poly(A) RNA binding // inferred from direct assay 202302_s_at NM_023012 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_023012.1 /DEF=Homo sapiens hypothetical protein FLJ11021 similar to splicing factor, arginineserine-rich 4 (FLJ11021), mRNA. /FEA=mRNA /GEN=FLJ11021 /PROD=hypothetical protein FLJ11021 similar tosplicing factor, arginineserine-rich 4 /DB_XREF=gi:12711677 /UG=Hs.81648 hypothetical protein FLJ11021 similar to splicing factor, arginineserine-rich 4 /FL=gb:NM_023012.1" NM_023012 arginine/serine-rich coiled-coil 2 RSRC2 65117 NM_023012 /// NM_198261 /// NM_198262 /// NR_036434 /// NR_036435 /// NR_036436 /// XM_005253601 /// XM_005253602 /// XM_005253604 /// XM_005253606 /// XR_242958 /// XR_242959 0044822 // poly(A) RNA binding // inferred from direct assay 202303_x_at NM_003601 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003601.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 (SMARCA5), mRNA. /FEA=mRNA /GEN=SMARCA5 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 5 /DB_XREF=gi:4507074 /UG=Hs.9456 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 /FL=gb:AB010882.1 gb:NM_003601.1" NM_003601 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5" SMARCA5 8467 NM_003601 "0000183 // chromatin silencing at rDNA // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006334 // nucleosome assembly // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from direct assay /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0043044 // ATP-dependent chromatin remodeling // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005677 // chromatin silencing complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0031010 // ISWI-type complex // inferred from electronic annotation /// 0031213 // RSF complex // inferred from physical interaction /// 0043596 // nuclear replication fork // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay" 202304_at NM_014923 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014923.1 /DEF=Homo sapiens KIAA0970 protein (KIAA0970), mRNA. /FEA=mRNA /GEN=KIAA0970 /PROD=KIAA0970 protein /DB_XREF=gi:7662419 /UG=Hs.103329 KIAA0970 protein /FL=gb:AB023187.1 gb:NM_014923.1" NM_014923 fibronectin type III domain containing 3A FNDC3A 22862 NM_001079673 /// NM_001278438 /// NM_014923 /// NR_103528 /// XM_006719777 0007286 // spermatid development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202305_s_at AI685892 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI685892 /FEA=EST /DB_XREF=gi:4897186 /DB_XREF=est:tu38a11.x1 /CLONE=IMAGE:2253308 /UG=Hs.103419 fasciculation and elongation protein zeta 2 (zygin II) /FL=gb:AF113124.1 gb:NM_005102.1 AI685892 fasciculation and elongation protein zeta 2 (zygin II) FEZ2 9637 NM_001042548 /// NM_005102 /// XM_006712153 /// XR_244972 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement 0005515 // protein binding // inferred from physical interaction 202306_at NM_002696 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002696.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide G (POLR2G), mRNA. /FEA=mRNA /GEN=POLR2G /PROD=polymerase (RNA) II (DNA directed) polypeptideG /DB_XREF=gi:4505946 /UG=Hs.14839 polymerase (RNA) II (DNA directed) polypeptide G /FL=gb:NM_002696.1 gb:U20659.1" NM_002696 polymerase (RNA) II (DNA directed) polypeptide G POLR2G 5436 NM_002696 "0000291 // nuclear-transcribed mRNA catabolic process, exonucleolytic // not recorded /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045948 // positive regulation of translational initiation // not recorded /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // not recorded" "0000932 // cytoplasmic mRNA processing body // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay" 0003697 // single-stranded DNA binding // not recorded /// 0003723 // RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // not recorded /// 0003899 // DNA-directed RNA polymerase activity // not recorded /// 0031369 // translation initiation factor binding // not recorded 202307_s_at NM_000593 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000593.2 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 2 (ABCB2), mRNA. /FEA=mRNA /GEN=ABCB2 /PROD=ATP-binding cassette, sub-family B, member 2 /DB_XREF=gi:9665247 /UG=Hs.158164 ATP-binding cassette, sub-family B (MDRTAP), member 2 /FL=gb:L21204.1 gb:L21205.1 gb:L21206.1 gb:L21207.1 gb:L21208.1 gb:NM_000593.2" NM_000593 "transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)" TAP1 6890 NM_000593 /// NM_001292022 "0001916 // positive regulation of T cell mediated cytotoxicity // /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015833 // peptide transport // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from mutant phenotype /// 0019885 // antigen processing and presentation of endogenous peptide antigen via MHC class I // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0046967 // cytosol to ER transport // inferred from mutant phenotype /// 0055085 // transmembrane transport // not recorded" 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0042825 // TAP complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015197 // peptide transporter activity // inferred from genetic interaction /// 0015197 // peptide transporter activity // inferred from mutant phenotype /// 0015421 // oligopeptide-transporting ATPase activity // /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0023029 // MHC class Ib protein binding // inferred from physical interaction /// 0042288 // MHC class I protein binding // inferred from electronic annotation /// 0042605 // peptide antigen binding // non-traceable author statement /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // not recorded /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043531 // ADP binding // inferred from direct assay /// 0046978 // TAP1 binding // inferred from sequence or structural similarity /// 0046979 // TAP2 binding // inferred from physical interaction /// 0046980 // tapasin binding //" 202308_at NM_004176 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004176.1 /DEF=Homo sapiens sterol regulatory element binding transcription factor 1 (SREBF1), mRNA. /FEA=mRNA /GEN=SREBF1 /PROD=sterol regulatory element binding transcriptionfactor 1 /DB_XREF=gi:4759167 /UG=Hs.166 sterol regulatory element binding transcription factor 1 /FL=gb:U00968.1 gb:NM_004176.1" NM_004176 sterol regulatory element binding transcription factor 1 SREBF1 6720 NM_001005291 /// NM_004176 /// XM_005256772 /// XM_006721570 /// XR_429821 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003062 // regulation of heart rate by chemical signal // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from sequence or structural similarity /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0009749 // response to glucose // inferred from electronic annotation /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0019217 // regulation of fatty acid metabolic process // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045542 // positive regulation of cholesterol biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032810 // sterol response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202309_at NM_005956 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005956.2 /DEF=Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1), mRNA. /FEA=mRNA /GEN=MTHFD1 /PROD=methylenetetrahydrofolate dehydrogenase (NADP+dependent), methenyltetrahydrofolate cyclohydrolase,formyltetrahydrofolate synthetase /DB_XREF=gi:13699867 /UG=Hs.172665 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase /FL=gb:NM_005956.2 gb:J04031.1" NM_005956 "methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase" MTHFD1 4522 NM_005956 0000105 // histidine biosynthetic process // inferred from electronic annotation /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon metabolic process // not recorded /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004329 // formate-tetrahydrofolate ligase activity // not recorded /// 0004329 // formate-tetrahydrofolate ligase activity // traceable author statement /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // not recorded /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // traceable author statement /// 0004486 // methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity // traceable author statement /// 0004488 // methylenetetrahydrofolate dehydrogenase (NADP+) activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202310_s_at K01228 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:K01228.1 /DEF=Human proalpha 1 (I) chain of type I procollagen mRNA (partial). /FEA=mRNA /GEN=COL1A1 /DB_XREF=gi:180391 /UG=Hs.172928 collagen, type I, alpha 1 /FL=gb:NM_000088.1" K01228 "collagen, type I, alpha 1" COL1A1 1277 NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703 "0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202311_s_at AI743621 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI743621 /FEA=EST /DB_XREF=gi:5111909 /DB_XREF=est:wg51h09.x1 /CLONE=IMAGE:2368673 /UG=Hs.172928 collagen, type I, alpha 1 /FL=gb:NM_000088.1" AI743621 "collagen, type I, alpha 1" COL1A1 1277 NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703 "0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202312_s_at NM_000088 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000088.1 /DEF=Homo sapiens collagen, type I, alpha 1 (COL1A1), mRNA. /FEA=mRNA /GEN=COL1A1 /PROD=collagen, type I, alpha 1 /DB_XREF=gi:4502944 /UG=Hs.172928 collagen, type I, alpha 1 /FL=gb:NM_000088.1" NM_000088 "collagen, type I, alpha 1" COL1A1 1277 NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703 "0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 202313_at NM_002717 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002717.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform (PPP2R2A), mRNA. /FEA=mRNA /GEN=PPP2R2A /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit B (PR 52), alpha isoform /DB_XREF=gi:4506018 /UG=Hs.179574 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform /FL=gb:M64929.1 gb:NM_002717.1" NM_002717 "protein phosphatase 2, regulatory subunit B, alpha" PPP2R2A 5520 NM_001177591 /// NM_002717 /// XM_005273559 /// XM_005273560 "0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043278 // response to morphine // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement" 0000159 // protein phosphatase type 2A complex // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement 202314_at NM_000786 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000786.1 /DEF=Homo sapiens cytochrome P450, 51 (lanosterol 14-alpha-demethylase) (CYP51), mRNA. /FEA=mRNA /GEN=CYP51 /PROD=cytochrome P450, 51 (lanosterol14-alpha-demethylase) /DB_XREF=gi:4503242 /UG=Hs.226213 cytochrome P450, 51 (lanosterol 14-alpha-demethylase) /FL=gb:U23942.1 gb:NM_000786.1 gb:D55653.1" NM_000786 "cytochrome P450, family 51, subfamily A, polypeptide 1 /// leucine-rich repeats and death domain containing 1" CYP51A1 /// LRRD1 1595 /// 401387 NM_000786 /// NM_001045475 /// NM_001146152 /// NM_001161528 "0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0033488 // cholesterol biosynthetic process via 24,25-dihydrolanosterol // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070988 // demethylation // inferred from direct assay /// 0070988 // demethylation // inferred from electronic annotation" 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008398 // sterol 14-demethylase activity // inferred from direct assay /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 202315_s_at NM_004327 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004327.2 /DEF=Homo sapiens breakpoint cluster region (BCR), transcript variant 1, mRNA. /FEA=mRNA /GEN=BCR /PROD=breakpoint cluster region, isoform 1 /DB_XREF=gi:11038638 /UG=Hs.234799 breakpoint cluster region /FL=gb:NM_004327.2" NM_004327 breakpoint cluster region BCR 613 NM_004327 /// NM_021574 0006468 // protein phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043314 // negative regulation of neutrophil degranulation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation 202316_x_at AW241715 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW241715 /FEA=EST /DB_XREF=gi:6575469 /DB_XREF=est:xn74b08.x1 /CLONE=IMAGE:2700183 /UG=Hs.24594 ubiquitination factor E4B (homologous to yeast UFD2) /FL=gb:AF043117.1 gb:NM_006048.1 AW241715 ubiquitination factor E4B UBE4B 10277 NM_001105562 /// NM_006048 /// XM_005263422 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 202317_s_at NM_006048 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006048.1 /DEF=Homo sapiens ubiquitination factor E4B (homologous to yeast UFD2) (UBE4B), mRNA. /FEA=mRNA /GEN=UBE4B /PROD=ubiquitination factor E4B (homologous to yeastUFD2) /DB_XREF=gi:5174482 /UG=Hs.24594 ubiquitination factor E4B (homologous to yeast UFD2) /FL=gb:AF043117.1 gb:NM_006048.1" NM_006048 ubiquitination factor E4B UBE4B 10277 NM_001105562 /// NM_006048 /// XM_005263422 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008626 // granzyme-mediated apoptotic signaling pathway // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from electronic annotation 202318_s_at AF306508 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF306508.1 /DEF=Homo sapiens SUMO-1 specific protease FKSG6 mRNA, complete cds. /FEA=mRNA /PROD=SUMO-1 specific protease FKSG6 /DB_XREF=gi:11096243 /UG=Hs.27197 SUMO-1-specific protease /FL=gb:AF307849.1 gb:AF306508.1 gb:AF196304.1 gb:NM_015571.1" AF306508 SUMO1/sentrin specific peptidase 6 SENP6 26054 NM_001100409 /// NM_015571 /// XM_006715457 /// XR_241847 0006508 // proteolysis // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016926 // protein desumoylation // inferred from mutant phenotype /// 0070646 // protein modification by small protein removal // inferred from direct assay /// 0090169 // regulation of spindle assembly // inferred from mutant phenotype /// 0090234 // regulation of kinetochore assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016929 // SUMO-specific protease activity // inferred from mutant phenotype 202319_at NM_015571 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015571.1 /DEF=Homo sapiens SUMO-1-specific protease (KIAA0797), mRNA. /FEA=mRNA /GEN=KIAA0797 /PROD=SUMO-1-specific protease /DB_XREF=gi:7662311 /UG=Hs.27197 SUMO-1-specific protease /FL=gb:AF307849.1 gb:AF306508.1 gb:AF196304.1 gb:NM_015571.1" NM_015571 SUMO1/sentrin specific peptidase 6 SENP6 26054 NM_001100409 /// NM_015571 /// XM_006715457 /// XR_241847 0006508 // proteolysis // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016926 // protein desumoylation // inferred from mutant phenotype /// 0070646 // protein modification by small protein removal // inferred from direct assay /// 0090169 // regulation of spindle assembly // inferred from mutant phenotype /// 0090234 // regulation of kinetochore assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016929 // SUMO-specific protease activity // inferred from mutant phenotype 202320_at NM_001520 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001520.1 /DEF=Homo sapiens general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ) (GTF3C1), mRNA. /FEA=mRNA /GEN=GTF3C1 /PROD=general transcription factor IIIC, polypeptide 1(alpha subunit, 220kD ) /DB_XREF=gi:4753160 /UG=Hs.331 general transcription factor IIIC, polypeptide 1 (alpha subunit, 220kD ) /FL=gb:U02619.1 gb:NM_001520.1" NM_001520 "general transcription factor IIIC, polypeptide 1, alpha 220kDa" GTF3C1 2975 NM_001286242 /// NM_001520 /// XM_006721042 "0006351 // transcription, DNA-templated // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // inferred by curator /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009303 // rRNA transcription // traceable author statement /// 0009304 // tRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator" 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 202321_at AW299507 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW299507 /FEA=EST /DB_XREF=gi:6709184 /DB_XREF=est:xs40e12.x1 /CLONE=IMAGE:2772142 /UG=Hs.55498 geranylgeranyl diphosphate synthase 1 /FL=gb:AF057698.1 gb:BC005252.1 gb:AB017971.1 gb:AB016043.1 gb:AB019036.1 gb:NM_004837.1 gb:AF125394.1 AW299507 geranylgeranyl diphosphate synthase 1 GGPS1 9453 NM_001037277 /// NM_001037278 /// NM_004837 /// NR_036605 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006720 // isoprenoid metabolic process // inferred from direct assay /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0033384 // geranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0033386 // geranylgeranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045337 // farnesyl diphosphate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from direct assay /// 0004337 // geranyltranstransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202322_s_at NM_004837 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004837.1 /DEF=Homo sapiens geranylgeranyl diphosphate synthase 1 (GGPS1), mRNA. /FEA=mRNA /GEN=GGPS1 /PROD=geranylgeranyl diphosphate synthase 1 /DB_XREF=gi:4758429 /UG=Hs.55498 geranylgeranyl diphosphate synthase 1 /FL=gb:AF057698.1 gb:BC005252.1 gb:AB017971.1 gb:AB016043.1 gb:AB019036.1 gb:NM_004837.1 gb:AF125394.1" NM_004837 geranylgeranyl diphosphate synthase 1 GGPS1 9453 NM_001037277 /// NM_001037278 /// NM_004837 /// NR_036605 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006720 // isoprenoid metabolic process // inferred from direct assay /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0033384 // geranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0033386 // geranylgeranyl diphosphate biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045337 // farnesyl diphosphate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from direct assay /// 0004337 // geranyltranstransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202323_s_at AI636775 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI636775 /FEA=EST /DB_XREF=gi:4688105 /DB_XREF=est:ts89h01.x1 /CLONE=IMAGE:2238481 /UG=Hs.6831 golgi resident protein GCP60 /FL=gb:AB043587.1 gb:NM_022735.1 AI636775 acyl-CoA binding domain containing 3 ACBD3 64746 NM_022735 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202324_s_at NM_022735 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022735.1 /DEF=Homo sapiens golgi resident protein GCP60 (GCP60), mRNA. /FEA=mRNA /GEN=GCP60 /PROD=golgi resident protein GCP60 /DB_XREF=gi:12232390 /UG=Hs.6831 golgi resident protein GCP60 /FL=gb:AB043587.1 gb:NM_022735.1" NM_022735 acyl-CoA binding domain containing 3 ACBD3 64746 NM_022735 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202325_s_at NM_001685 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001685.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 (ATP5J), mRNA. /FEA=mRNA /GEN=ATP5J /PROD=ATP synthase, H+ transporting, mitochondrial /DB_XREF=gi:4502292 /UG=Hs.73851 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 /FL=gb:M37104.1 gb:M73031.1 gb:NM_001685.1 gb:AL110183.1" NM_001685 "ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6" ATP5J 522 NM_001003696 /// NM_001003697 /// NM_001003701 /// NM_001003703 /// NM_001685 /// XM_005260992 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement "0000276 // mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation" 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 202326_at NM_006709 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006709.1 /DEF=Homo sapiens ankyrin repeat-containing protein (G9A), mRNA. /FEA=mRNA /GEN=G9A /PROD=ankyrin repeat-containing protein /DB_XREF=gi:5729833 /UG=Hs.75196 ankyrin repeat-containing protein /FL=gb:BC002686.1 gb:NM_006709.1" NM_006709 euchromatic histone-lysine N-methyltransferase 2 EHMT2 10919 NM_001289413 /// NM_006709 /// NM_025256 /// XM_005248824 /// XM_005272767 /// XM_005274833 /// XM_005274835 /// XM_005274913 /// XM_005275207 /// XM_005275209 /// XM_005275343 /// XM_005275345 /// XM_006714974 /// XM_006714975 /// XM_006714976 /// XM_006725028 /// XM_006725029 /// XM_006725467 /// XM_006725468 /// XM_006725469 /// XM_006725682 /// XM_006725683 /// XM_006725684 /// XM_006725892 /// XM_006725893 /// XM_006725981 /// XM_006725982 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006275 // regulation of DNA replication // inferred from mutant phenotype /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0007286 // spermatid development // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0010424 // DNA methylation on cytosine within a CG sequence // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from mutant phenotype /// 0018027 // peptidyl-lysine dimethylation // inferred from direct assay /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation 0002039 // p53 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016279 // protein-lysine N-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046974 // histone methyltransferase activity (H3-K9 specific) // inferred from sequence or structural similarity /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from sequence or structural similarity /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202327_s_at AA020938 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA020938 /FEA=EST /DB_XREF=gi:1484673 /DB_XREF=est:ze64c09.s1 /CLONE=IMAGE:363760 /UG=Hs.75813 polycystic kidney disease 1 (autosomal dominant) /FL=gb:NM_000296.1 gb:U24497.1 gb:L33243.1 AA020938 polycystin-1-like /// polycystic kidney disease 1 (autosomal dominant) LOC101930075 /// PKD1 5310 /// 101930075 NM_000296 /// NM_001009944 /// XM_005255370 /// XM_005276493 /// XM_006720889 /// XM_006720890 /// XM_006720891 /// XM_006720892 /// XM_006720893 /// XM_006720894 /// XM_006720895 /// XR_429642 /// XR_429643 0001502 // cartilage condensation // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007161 // calcium-independent cell-matrix adhesion // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from sequence or structural similarity /// 0043588 // skin development // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048565 // digestive tract development // inferred from expression pattern /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0048806 // genitalia development // inferred from expression pattern /// 0050982 // detection of mechanical stimulus // not recorded /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from expression pattern /// 0060236 // regulation of mitotic spindle organization // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from expression pattern /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // not recorded /// 0072001 // renal system development // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072205 // metanephric collecting duct development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072237 // metanephric proximal tubule development // inferred from expression pattern /// 0072287 // metanephric distal tubule morphogenesis // inferred from expression pattern 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 202328_s_at NM_000296 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000296.1 /DEF=Homo sapiens polycystic kidney disease 1 (autosomal dominant) (PKD1), mRNA. /FEA=mRNA /GEN=PKD1 /PROD=polycystic kidney disease 1 (autosomaldominant) /DB_XREF=gi:4505832 /UG=Hs.75813 polycystic kidney disease 1 (autosomal dominant) /FL=gb:NM_000296.1 gb:U24497.1 gb:L33243.1" NM_000296 polycystin-1-like /// polycystic kidney disease 1 (autosomal dominant) LOC101930075 /// PKD1 5310 /// 101930075 NM_000296 /// NM_001009944 /// XM_005255370 /// XM_005276493 /// XM_006720889 /// XM_006720890 /// XM_006720891 /// XM_006720892 /// XM_006720893 /// XM_006720894 /// XM_006720895 /// XR_429642 /// XR_429643 0001502 // cartilage condensation // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007156 // homophilic cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007161 // calcium-independent cell-matrix adhesion // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from expression pattern /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from sequence or structural similarity /// 0043588 // skin development // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048565 // digestive tract development // inferred from expression pattern /// 0048754 // branching morphogenesis of an epithelial tube // inferred from direct assay /// 0048806 // genitalia development // inferred from expression pattern /// 0050982 // detection of mechanical stimulus // not recorded /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from expression pattern /// 0060236 // regulation of mitotic spindle organization // inferred from electronic annotation /// 0060428 // lung epithelium development // inferred from expression pattern /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // not recorded /// 0072001 // renal system development // inferred from electronic annotation /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072205 // metanephric collecting duct development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072237 // metanephric proximal tubule development // inferred from expression pattern /// 0072287 // metanephric distal tubule morphogenesis // inferred from expression pattern 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005929 // cilium // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction 202329_at NM_004383 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004383.1 /DEF=Homo sapiens c-src tyrosine kinase (CSK), mRNA. /FEA=mRNA /GEN=CSK /PROD=c-src tyrosine kinase /DB_XREF=gi:4758077 /UG=Hs.77793 c-src tyrosine kinase /FL=gb:NM_004383.1" NM_004383 c-src tyrosine kinase CSK 1445 NM_001127190 /// NM_004383 /// XM_005254165 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010989 // negative regulation of low-density lipoprotein particle clearance // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0033673 // negative regulation of kinase activity // inferred from electronic annotation /// 0034332 // adherens junction organization // inferred from electronic annotation /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060368 // regulation of Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from physical interaction /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from electronic annotation" 202330_s_at NM_003362 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003362.1 /DEF=Homo sapiens uracil-DNA glycosylase (UNG), mRNA. /FEA=mRNA /GEN=UNG /PROD=uracil-DNA glycosylase /DB_XREF=gi:6224978 /UG=Hs.78853 uracil-DNA glycosylase /FL=gb:NM_003362.1" NM_003362 uracil-DNA glycosylase UNG 7374 NM_003362 /// NM_080911 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from electronic annotation /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation "0004844 // uracil DNA N-glycosylase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation" 202331_at NM_000709 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000709.1 /DEF=Homo sapiens branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease) (BCKDHA), mRNA. /FEA=mRNA /GEN=BCKDHA /PROD=branched chain keto acid dehydrogenase E1, alphapolypeptide (maple syrup urine disease) /DB_XREF=gi:11386134 /UG=Hs.78950 branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease) /FL=gb:NM_000709.1" NM_000709 "branched chain keto acid dehydrogenase E1, alpha polypeptide" BCKDHA 593 NM_000709 /// NM_001164783 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // inferred from direct assay /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005947 // mitochondrial alpha-ketoglutarate dehydrogenase complex // inferred from direct assay "0003826 // alpha-ketoacid dehydrogenase activity // inferred from direct assay /// 0003863 // 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation" 202332_at NM_001894 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001894.1 /DEF=Homo sapiens casein kinase 1, epsilon (CSNK1E), mRNA. /FEA=mRNA /GEN=CSNK1E /PROD=casein kinase 1, epsilon /DB_XREF=gi:4503092 /UG=Hs.79658 casein kinase 1, epsilon /FL=gb:NM_001894.1 gb:AB024597.1 gb:L37043.1" NM_001894 "LOC400927-CSNK1E readthrough /// casein kinase 1, epsilon" CSNK1E /// CSNK1E 1454 /// 102800317 NM_001289912 /// NM_001894 /// NM_152221 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 202333_s_at AA877765 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA877765 /FEA=EST /DB_XREF=gi:2986730 /DB_XREF=est:nr06f05.s1 /CLONE=IMAGE:1161057 /UG=Hs.811 ubiquitin-conjugating enzyme E2B (RAD6 homolog) /FL=gb:M74525.1 gb:NM_003337.1 AA877765 ubiquitin-conjugating enzyme E2B UBE2B 7320 NM_003337 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006301 // postreplication repair // non-traceable author statement /// 0006344 // maintenance of chromatin silencing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from genetic interaction /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031056 // regulation of histone modification // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051026 // chiasma assembly // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0070076 // histone lysine demethylation // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 202334_s_at AI768723 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI768723 /FEA=EST /DB_XREF=gi:5235232 /DB_XREF=est:wh25c12.x1 /CLONE=IMAGE:2381782 /UG=Hs.811 ubiquitin-conjugating enzyme E2B (RAD6 homolog) /FL=gb:M74525.1 gb:NM_003337.1 AI768723 ubiquitin-conjugating enzyme E2B UBE2B 7320 NM_003337 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006301 // postreplication repair // non-traceable author statement /// 0006344 // maintenance of chromatin silencing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from genetic interaction /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031056 // regulation of histone modification // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051026 // chiasma assembly // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0070076 // histone lysine demethylation // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 202335_s_at NM_003337 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003337.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2B (RAD6 homolog) (UBE2B), mRNA. /FEA=mRNA /GEN=UBE2B /PROD=ubiquitin-conjugating enzyme E2B (RAD6 homolog) /DB_XREF=gi:4507770 /UG=Hs.811 ubiquitin-conjugating enzyme E2B (RAD6 homolog) /FL=gb:M74525.1 gb:NM_003337.1" NM_003337 ubiquitin-conjugating enzyme E2B UBE2B 7320 NM_003337 0000209 // protein polyubiquitination // inferred from mutant phenotype /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006281 // DNA repair // inferred from genetic interaction /// 0006301 // postreplication repair // inferred from direct assay /// 0006301 // postreplication repair // non-traceable author statement /// 0006344 // maintenance of chromatin silencing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0006513 // protein monoubiquitination // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007283 // spermatogenesis // traceable author statement /// 0007288 // sperm axoneme assembly // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009411 // response to UV // inferred from genetic interaction /// 0010845 // positive regulation of reciprocal meiotic recombination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031056 // regulation of histone modification // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033128 // negative regulation of histone phosphorylation // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from mutant phenotype /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043951 // negative regulation of cAMP-mediated signaling // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051026 // chiasma assembly // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0070076 // histone lysine demethylation // inferred from electronic annotation /// 0070193 // synaptonemal complex organization // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0000785 // chromatin // inferred from sequence or structural similarity /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033503 // HULC complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 202336_s_at NM_000919 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000919.1 /DEF=Homo sapiens peptidylglycine alpha-amidating monooxygenase (PAM), mRNA. /FEA=mRNA /GEN=PAM /PROD=peptidylglycine alpha-amidating monooxygenase /DB_XREF=gi:4505602 /UG=Hs.83920 peptidylglycine alpha-amidating monooxygenase /FL=gb:M37721.1 gb:NM_000919.1" NM_000919 peptidylglycine alpha-amidating monooxygenase PAM 5066 NM_000919 /// NM_001177306 /// NM_138766 /// NM_138821 /// NM_138822 /// NR_033440 /// XM_006714632 /// XM_006714633 /// XM_006714634 /// XM_006714635 /// XM_006714636 /// XM_006714637 /// XM_006714638 /// XM_006714639 /// XM_006714640 0001519 // peptide amidation // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006518 // peptide metabolic process // inferred from electronic annotation /// 0006518 // peptide metabolic process // non-traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from mutant phenotype /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009268 // response to pH // inferred from electronic annotation /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0018032 // protein amidation // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0022602 // ovulation cycle process // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0042476 // odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030141 // secretory granule // non-traceable author statement /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003682 // chromatin binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004504 // peptidylglycine monooxygenase activity // inferred from direct assay /// 0004598 // peptidylamidoglycolate lyase activity // inferred from direct assay /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016715 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 202337_at NM_007221 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007221.1 /DEF=Homo sapiens polyamine-modulated factor 1 (PMF1), mRNA. /FEA=mRNA /GEN=PMF1 /PROD=polyamine-modulated factor 1 /DB_XREF=gi:6005831 /UG=Hs.94446 polyamine-modulated factor 1 /FL=gb:AF141310.1 gb:NM_007221.1" NM_007221 polyamine-modulated factor 1 PMF1 11243 NM_001199653 /// NM_001199654 /// NM_007221 "0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" "0000444 // MIS12/MIND type complex // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement" 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0043522 // leucine zipper domain binding // inferred from physical interaction 202338_at NM_003258 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003258.1 /DEF=Homo sapiens thymidine kinase 1, soluble (TK1), mRNA. /FEA=mRNA /GEN=TK1 /PROD=thymidine kinase 1, soluble /DB_XREF=gi:4507518 /UG=Hs.105097 thymidine kinase 1, soluble /FL=gb:K02581.1 gb:NM_003258.1" NM_003258 "thymidine kinase 1, soluble" TK1 7083 NM_003258 /// XM_005257631 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014856 // skeletal muscle cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051414 // response to cortisol // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060138 // fetal process involved in parturition // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202339_at NM_004819 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004819.1 /DEF=Homo sapiens symplekin; Huntingtin interacting protein I (SPK), mRNA. /FEA=mRNA /GEN=SPK /PROD=symplekin /DB_XREF=gi:4759195 /UG=Hs.107019 symplekin; Huntingtin interacting protein I /FL=gb:U49240.1 gb:NM_004819.1" NM_004819 symplekin SYMPK 8189 NM_004819 /// XM_005259286 /// XR_243962 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006398 // histone mRNA 3'-end processing // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202340_x_at NM_002135 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002135.1 /DEF=Homo sapiens nuclear receptor subfamily 4, group A, member 1 (NR4A1), mRNA. /FEA=mRNA /GEN=NR4A1 /PROD=nuclear receptor subfamily 4, group A, member 1 /DB_XREF=gi:4504440 /UG=Hs.1119 nuclear receptor subfamily 4, group A, member 1 /FL=gb:L13740.1 gb:NM_002135.1" NM_002135 "nuclear receptor subfamily 4, group A, member 1" NR4A1 3164 NM_001202233 /// NM_001202234 /// NM_002135 /// NM_173157 /// NM_173158 /// XM_005268822 /// XM_005268823 /// XM_005268824 /// XM_006719363 /// XM_006719364 "0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202341_s_at AA149745 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA149745 /FEA=EST /DB_XREF=gi:1720818 /DB_XREF=est:zo02h04.s1 /CLONE=IMAGE:566551 /UG=Hs.12372 tripartite motif protein TRIM2 /FL=gb:AF220018.1 gb:NM_015271.1 AA149745 tripartite motif containing 2 TRIM2 23321 NM_001130067 /// NM_015271 /// XM_006714157 /// XM_006714158 /// XM_006714159 /// XM_006714160 /// XM_006714161 /// XM_006714162 /// XM_006714163 /// XM_006714164 /// XM_006714165 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202342_s_at NM_015271 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015271.1 /DEF=Homo sapiens tripartite motif protein TRIM2 (KIAA0517), mRNA. /FEA=mRNA /GEN=KIAA0517 /PROD=tripartite motif protein TRIM2 /DB_XREF=gi:13446226 /UG=Hs.12372 tripartite motif protein TRIM2 /FL=gb:AF220018.1 gb:NM_015271.1" NM_015271 tripartite motif containing 2 TRIM2 23321 NM_001130067 /// NM_015271 /// XM_006714157 /// XM_006714158 /// XM_006714159 /// XM_006714160 /// XM_006714161 /// XM_006714162 /// XM_006714163 /// XM_006714164 /// XM_006714165 0008219 // cell death // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0043523 // regulation of neuron apoptotic process // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202343_x_at NM_001862 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001862.1 /DEF=Homo sapiens cytochrome c oxidase subunit Vb (COX5B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX5B /PROD=cytochrome c oxidase subunit Vb /DB_XREF=gi:4502982 /UG=Hs.1342 cytochrome c oxidase subunit Vb /FL=gb:M19961.1 gb:NM_001862.1" NM_001862 cytochrome c oxidase subunit Vb COX5B 1329 NM_001862 0007585 // respiratory gaseous exchange // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202344_at NM_005526 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005526.1 /DEF=Homo sapiens heat shock transcription factor 1 (HSF1), mRNA. /FEA=mRNA /GEN=HSF1 /PROD=heat shock transcription factor 1 /DB_XREF=gi:5031766 /UG=Hs.1499 heat shock transcription factor 1 /FL=gb:M64673.1 gb:NM_005526.1" NM_005526 heat shock transcription factor 1 HSF1 3297 NM_005526 /// XM_005272315 /// XM_005272316 /// XM_005272317 /// XR_246618 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0007143 // female meiotic division // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0090231 // regulation of spindle checkpoint // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001162 // RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202345_s_at NM_001444 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001444.1 /DEF=Homo sapiens fatty acid binding protein 5 (psoriasis-associated) (FABP5), mRNA. /FEA=mRNA /GEN=FABP5 /PROD=fatty acid binding protein 5(psoriasis-associated) /DB_XREF=gi:4557580 /UG=Hs.153179 fatty acid binding protein 5 (psoriasis-associated) /FL=gb:M94856.1 gb:NM_001444.1" NM_001444 fatty acid binding protein 5 (psoriasis-associated) FABP5 2171 NM_001444 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0009611 // response to wounding // inferred from electronic annotation /// 0015758 // glucose transport // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement 202346_at NM_005339 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005339.2 /DEF=Homo sapiens huntingtin interacting protein 2 (HIP2), mRNA. /FEA=mRNA /GEN=HIP2 /PROD=huntingtin interacting protein 2 /DB_XREF=gi:12545382 /UG=Hs.155485 huntingtin interacting protein 2 /FL=gb:NM_005339.2 gb:U58522.1 gb:AB022435.1" NM_005339 ubiquitin-conjugating enzyme E2K UBE2K 3093 NM_001111112 /// NM_001111113 /// NM_005339 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 202347_s_at AB022435 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB022435.1 /DEF=Homo sapiens LIG mRNA for E2 ubiquitin-conjugating enzyme, complete cds. /FEA=mRNA /GEN=LIG /PROD=E2 ubiquitin-conjugating enzyme /DB_XREF=gi:4996607 /UG=Hs.155485 huntingtin interacting protein 2 /FL=gb:NM_005339.2 gb:U58522.1 gb:AB022435.1" AB022435 ubiquitin-conjugating enzyme E2K UBE2K 3093 NM_001111112 /// NM_001111113 /// NM_005339 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay 202348_s_at BC000674 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000674.1 /DEF=Homo sapiens, dystonia 1, torsion (autosomal dominant; torsin A), clone MGC:1558, mRNA, complete cds. /FEA=mRNA /PROD=dystonia 1, torsion (autosomal dominant; torsinA) /DB_XREF=gi:12653776 /UG=Hs.19261 dystonia 1, torsion (autosomal dominant; torsin A) /FL=gb:BC000674.1 gb:AF007871.1 gb:NM_000113.1" BC000674 "torsin family 1, member A (torsin A)" TOR1A 1861 NM_000113 "0000338 // protein deneddylation // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0006996 // organelle organization // inferred from sequence or structural similarity /// 0006998 // nuclear envelope organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0044319 // wound healing, spreading of cells // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0048489 // synaptic vesicle transport // inferred from mutant phenotype /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071712 // ER-associated misfolded protein catabolic process // inferred from sequence or structural similarity /// 0071763 // nuclear membrane organization // inferred from sequence or structural similarity /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 1900244 // positive regulation of synaptic vesicle endocytosis // inferred from mutant phenotype /// 2000008 // regulation of protein localization to cell surface // inferred from mutant phenotype" 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement 202349_at NM_000113 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000113.1 /DEF=Homo sapiens dystonia 1, torsion (autosomal dominant; torsin A) (DYT1), mRNA. /FEA=mRNA /GEN=DYT1 /PROD=torsin A /DB_XREF=gi:4557540 /UG=Hs.19261 dystonia 1, torsion (autosomal dominant; torsin A) /FL=gb:BC000674.1 gb:AF007871.1 gb:NM_000113.1" NM_000113 "torsin family 1, member A (torsin A)" TOR1A 1861 NM_000113 "0000338 // protein deneddylation // inferred from mutant phenotype /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0006996 // organelle organization // inferred from sequence or structural similarity /// 0006998 // nuclear envelope organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0044319 // wound healing, spreading of cells // inferred from sequence or structural similarity /// 0045104 // intermediate filament cytoskeleton organization // inferred from mutant phenotype /// 0048489 // synaptic vesicle transport // inferred from mutant phenotype /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051584 // regulation of dopamine uptake involved in synaptic transmission // inferred from direct assay /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071712 // ER-associated misfolded protein catabolic process // inferred from sequence or structural similarity /// 0071763 // nuclear membrane organization // inferred from sequence or structural similarity /// 0072321 // chaperone-mediated protein transport // inferred from direct assay /// 1900244 // positive regulation of synaptic vesicle endocytosis // inferred from mutant phenotype /// 2000008 // regulation of protein localization to cell surface // inferred from mutant phenotype" 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0042406 // extrinsic component of endoplasmic reticulum membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0019894 // kinesin binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement 202350_s_at NM_002380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002380.2 /DEF=Homo sapiens matrilin 2 (MATN2) precursor, transcript variant 1, mRNA. /FEA=mRNA /GEN=MATN2 /PROD=matrilin 2 precursor /DB_XREF=gi:13518036 /UG=Hs.19368 matrilin 2 /FL=gb:U69263.2 gb:NM_002380.2" NM_002380 uncharacterized LOC100506558 /// matrilin 2 LOC100506558 /// MATN2 4147 /// 100506558 NM_002380 /// NM_030583 /// XM_005250920 /// XR_108869 /// XR_133494 /// XR_171741 0001764 // neuron migration // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0008347 // glial cell migration // inferred from electronic annotation /// 0031104 // dendrite regeneration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202351_at AI093579 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI093579 /FEA=EST /DB_XREF=gi:3432555 /DB_XREF=est:qb15g06.x1 /CLONE=IMAGE:1696378 /UG=Hs.295726 integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) /FL=gb:M14648.1 gb:NM_002210.1" AI093579 "integrin, alpha V" ITGAV 3685 NM_001144999 /// NM_001145000 /// NM_002210 /// XM_005246536 /// XM_006712513 "0001525 // angiogenesis // inferred from expression pattern /// 0001568 // blood vessel development // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0007155 // cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010888 // negative regulation of lipid storage // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0033690 // positive regulation of osteoblast proliferation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from mutant phenotype /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0046718 // viral entry into host cell // traceable author statement /// 0050748 // negative regulation of lipoprotein metabolic process // inferred from mutant phenotype /// 0050764 // regulation of phagocytosis // inferred from direct assay /// 0050900 // leukocyte migration // traceable author statement /// 0052066 // entry of symbiont into host cell by promotion of host phagocytosis // non-traceable author statement /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from sequence or structural similarity /// 2000425 // regulation of apoptotic cell clearance // inferred from sequence or structural similarity /// 2000536 // negative regulation of entry of bacterium into host cell // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008305 // integrin complex // inferred from direct assay /// 0008305 // integrin complex // non-traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035867 // alphav-beta3 integrin-IGF-1-IGF1R complex // inferred from direct assay /// 0045335 // phagocytic vesicle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0001846 // opsonin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031994 // insulin-like growth factor I binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity 202352_s_at AI446530 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI446530 /FEA=EST /DB_XREF=gi:4295855 /DB_XREF=est:tj05b01.x1 /CLONE=IMAGE:2140585 /UG=Hs.4295 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 /FL=gb:AB003103.1 gb:NM_002816.1" AI446530 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 12" PSMD12 5718 NM_002816 /// NM_174871 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202353_s_at NM_002816 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002816.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (PSMD12), mRNA. /FEA=mRNA /GEN=PSMD12 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 12 /DB_XREF=gi:4506220 /UG=Hs.4295 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 /FL=gb:AB003103.1 gb:NM_002816.1" NM_002816 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 12" PSMD12 5718 NM_002816 /// NM_174871 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005838 // proteasome regulatory particle // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202354_s_at AW190445 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW190445 /FEA=EST /DB_XREF=gi:6464925 /DB_XREF=est:xl15c01.x1 /CLONE=IMAGE:2676288 /UG=Hs.68257 general transcription factor IIF, polypeptide 1 (74kD subunit) /FL=gb:BC000120.1 gb:NM_002096.1" AW190445 "general transcription factor IIF, polypeptide 1, 74kDa" GTF2F1 2962 NM_002096 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005674 // transcription factor TFIIF complex // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202355_s_at BC000120 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000120.1 /DEF=Homo sapiens, general transcription factor IIF, polypeptide 1 (74kD subunit), clone MGC:1732, mRNA, complete cds. /FEA=mRNA /PROD=general transcription factor IIF, polypeptide 1(74kD subunit) /DB_XREF=gi:12652738 /UG=Hs.68257 general transcription factor IIF, polypeptide 1 (74kD subunit) /FL=gb:BC000120.1 gb:NM_002096.1" BC000120 "general transcription factor IIF, polypeptide 1, 74kDa" GTF2F1 2962 NM_002096 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005674 // transcription factor TFIIF complex // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202356_s_at NM_002096 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002096.1 /DEF=Homo sapiens general transcription factor IIF, polypeptide 1 (74kD subunit) (GTF2F1), mRNA. /FEA=mRNA /GEN=GTF2F1 /PROD=general transcription factor IIF, polypeptide 1(74kD subunit) /DB_XREF=gi:4504196 /UG=Hs.68257 general transcription factor IIF, polypeptide 1 (74kD subunit) /FL=gb:BC000120.1 gb:NM_002096.1" NM_002096 "general transcription factor IIF, polypeptide 1, 74kDa" GTF2F1 2962 NM_002096 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005674 // transcription factor TFIIF complex // traceable author statement /// 0030054 // cell junction // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202357_s_at NM_001710 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001710.1 /DEF=Homo sapiens B-factor, properdin (BF), mRNA. /FEA=mRNA /GEN=BF /PROD=B-factor, properdin /DB_XREF=gi:4502396 /UG=Hs.69771 B-factor, properdin /FL=gb:BC004143.1 gb:L15702.1 gb:NM_001710.1 gb:S67310.1" NM_001710 complement factor B CFB 629 NM_001710 "0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // non-traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0001848 // complement binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202358_s_at BG434168 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG434168 /FEA=EST /DB_XREF=gi:13340674 /DB_XREF=est:602506096F1 /CLONE=IMAGE:4603630 /UG=Hs.76906 KIAA0254 gene product /FL=gb:D87443.1 gb:NM_014758.1 BG434168 sorting nexin 19 SNX19 399979 NM_014758 /// XM_005271545 /// XM_005271546 /// XM_005271548 /// XM_005271549 /// XR_428976 /// XR_428977 0006810 // transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 202359_s_at NM_014758 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014758.1 /DEF=Homo sapiens KIAA0254 gene product (KIAA0254), mRNA. /FEA=mRNA /GEN=KIAA0254 /PROD=KIAA0254 gene product /DB_XREF=gi:7662025 /UG=Hs.76906 KIAA0254 gene product /FL=gb:D87443.1 gb:NM_014758.1" NM_014758 sorting nexin 19 SNX19 399979 NM_014758 /// XM_005271545 /// XM_005271546 /// XM_005271548 /// XM_005271549 /// XR_428976 /// XR_428977 0006810 // transport // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 202360_at NM_014757 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014757.2 /DEF=Homo sapiens mastermind (Drosophila), homolog of (MAML1), mRNA. /FEA=mRNA /GEN=MAML1 /PROD=homolog of Drosophila mastermind /DB_XREF=gi:13376996 /UG=Hs.76986 mastermind (Drosophila), homolog of /FL=gb:NM_014757.2 gb:D83785.1" NM_014757 mastermind-like 1 (Drosophila) MAML1 9794 NM_014757 "0003162 // atrioventricular node development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from genetic interaction /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // inferred from electronic annotation /// 0060928 // atrioventricular node cell development // inferred from sequence or structural similarity" 0002193 // MAML1-RBP-Jkappa- ICN1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from physical interaction 202361_at NM_004922 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004922.1 /DEF=Homo sapiens SEC24 (S. cerevisiae) related gene family, member C (SEC24C), mRNA. /FEA=mRNA /GEN=SEC24C /PROD=SEC24 (S. cerevisiae) related gene family,member C /DB_XREF=gi:4758633 /UG=Hs.81964 SEC24 (S. cerevisiae) related gene family, member C /FL=gb:NM_004922.1 gb:D38555.1" NM_004922 SEC24 family member C SEC24C 9632 NM_004922 /// NM_198597 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 202362_at NM_002884 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002884.1 /DEF=Homo sapiens RAP1A, member of RAS oncogene family (RAP1A), mRNA. /FEA=mRNA /GEN=RAP1A /PROD=RAP1A, member of RAS oncogene family /DB_XREF=gi:4506412 /UG=Hs.865 RAP1A, member of RAS oncogene family /FL=gb:NM_002884.1 gb:M22995.1" NM_002884 "RAP1A, member of RAS oncogene family" RAP1A 5906 NM_001010935 /// NM_001291896 /// NM_002884 /// XM_006710803 /// XR_246288 0000186 // activation of MAPKK activity // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from sequence or structural similarity /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from direct assay 202363_at AF231124 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF231124.1 /DEF=Homo sapiens testican-1 mRNA, complete cds. /FEA=mRNA /PROD=testican-1 /DB_XREF=gi:7248844 /UG=Hs.93029 sparcosteonectin, cwcv and kazal-like domains proteoglycan (testican) /FL=gb:NM_004598.1 gb:AF231124.1" AF231124 "sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1" SPOCK1 6695 NM_004598 0001558 // regulation of cell growth // non-traceable author statement /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0010812 // negative regulation of cell-substrate adhesion // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0021953 // central nervous system neuron differentiation // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // non-traceable author statement /// 0016528 // sarcoplasm // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay 202364_at NM_005962 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005962.1 /DEF=Homo sapiens MAX-interacting protein 1 (MXI1), mRNA. /FEA=mRNA /GEN=MXI1 /PROD=MAX-interacting protein 1 /DB_XREF=gi:5174596 /UG=Hs.118630 MAX-interacting protein 1 /FL=gb:L07648.1 gb:NM_005962.1 gb:D63940.1" NM_005962 "MAX interactor 1, dimerization protein" MXI1 4601 NM_001008541 /// NM_005962 /// NM_130439 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation 202365_at BC004815 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC004815.1 /DEF=Homo sapiens, clone MGC:5139, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:5139) /DB_XREF=gi:13435956 /UG=Hs.127610 acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain /FL=gb:BC004815.1 gb:M26393.1 gb:NM_000017.1" BC004815 unc-119 homolog B (C. elegans) UNC119B 84747 NM_001080533 /// NM_032661 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from direct assay /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0005929 // cilium // inferred from electronic annotation /// 0035869 // ciliary transition zone // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 202366_at NM_000017 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000017.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain (ACADS), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADS /PROD=acyl-Coenzyme A dehydrogenase, C-2 to C-3 shortchain precursor /DB_XREF=gi:4557232 /UG=Hs.127610 acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain /FL=gb:BC004815.1 gb:M26393.1 gb:NM_000017.1" NM_000017 "acyl-CoA dehydrogenase, C-2 to C-3 short chain" ACADS 35 NM_000017 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046359 // butyrate catabolic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation "0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0004085 // butyryl-CoA dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 202367_at NM_001913 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001913.1 /DEF=Homo sapiens cut (Drosophila)-like 1 (CCAAT displacement protein) (CUTL1), mRNA. /FEA=mRNA /GEN=CUTL1 /PROD=cut (Drosophila)-like 1 (CCAAT displacementprotein) /DB_XREF=gi:4503168 /UG=Hs.147049 cut (Drosophila)-like 1 (CCAAT displacement protein) /FL=gb:NM_001913.1 gb:L12579.1" NM_001913 cut-like homeobox 1 CUX1 1523 NM_001202543 /// NM_001202544 /// NM_001202545 /// NM_001202546 /// NM_001913 /// NM_181500 /// NM_181552 /// XM_005250150 /// XM_005250151 /// XM_005250154 /// XM_006715854 /// XM_006715855 /// XM_006715856 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000301 // retrograde transport, vesicle recycling within Golgi // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation "0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay" 202368_s_at AI986461 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI986461 /FEA=EST /DB_XREF=gi:5813738 /DB_XREF=est:wz65f07.x1 /CLONE=IMAGE:2562949 /UG=Hs.153954 TRAM-like protein /FL=gb:D31762.1 gb:NM_012288.1 AI986461 translocation associated membrane protein 2 TRAM2 9697 NM_012288 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202369_s_at NM_012288 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012288.1 /DEF=Homo sapiens TRAM-like protein (KIAA0057), mRNA. /FEA=mRNA /GEN=KIAA0057 /PROD=TRAM-like protein /DB_XREF=gi:6912449 /UG=Hs.153954 TRAM-like protein /FL=gb:D31762.1 gb:NM_012288.1" NM_012288 translocation associated membrane protein 2 TRAM2 9697 NM_012288 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202370_s_at NM_001755 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001755.1 /DEF=Homo sapiens core-binding factor, beta subunit (CBFB), transcript variant 2, mRNA. /FEA=mRNA /GEN=CBFB /PROD=core-binding factor, beta subunit, isoform 2 /DB_XREF=gi:13124872 /UG=Hs.179881 core-binding factor, beta subunit /FL=gb:NM_001755.1" NM_001755 "core-binding factor, beta subunit" CBFB 865 NM_001755 /// NM_022845 /// XM_005256212 /// XM_006721321 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202371_at NM_024863 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024863.1 /DEF=Homo sapiens hypothetical protein FLJ21174 (FLJ21174), mRNA. /FEA=mRNA /GEN=FLJ21174 /PROD=hypothetical protein FLJ21174 /DB_XREF=gi:13376293 /UG=Hs.194329 hypothetical protein FLJ21174 /FL=gb:AF271783.1 gb:NM_024863.1" NM_024863 transcription elongation factor A (SII)-like 4 TCEAL4 79921 NM_001006935 /// NM_001006936 /// NM_001006937 /// NM_024863 /// XM_005262192 /// XM_005262193 /// XM_005262194 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003746 // translation elongation factor activity // inferred from electronic annotation 202372_at BF240652 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF240652 /FEA=EST /DB_XREF=gi:11154576 /DB_XREF=est:601875908F1 /CLONE=IMAGE:4099824 /UG=Hs.197289 rab3 GTPase-activating protein, non-catalytic subunit (150kD) /FL=gb:AF255648.1 gb:AF004828.1 gb:NM_012414.1" BF240652 aurora kinase A pseudogene 1 /// RAB3 GTPase activating protein subunit 2 (non-catalytic) AURKAPS1 /// RAB3GAP2 6791 /// 25782 NM_012414 /// NR_001587 0006886 // intracellular protein transport // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0030234 // enzyme regulator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 202373_s_at AF255648 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF255648.1 /DEF=Homo sapiens rGAP-iso mRNA, complete cds. /FEA=mRNA /PROD=rGAP-iso /DB_XREF=gi:12005820 /UG=Hs.197289 rab3 GTPase-activating protein, non-catalytic subunit (150kD) /FL=gb:AF255648.1 gb:AF004828.1 gb:NM_012414.1" AF255648 aurora kinase A pseudogene 1 /// RAB3 GTPase activating protein subunit 2 (non-catalytic) AURKAPS1 /// RAB3GAP2 6791 /// 25782 NM_012414 /// NR_001587 0006364 // rRNA processing // inferred from sequence or structural similarity /// 0006886 // intracellular protein transport // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0030234 // enzyme regulator activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 202374_s_at NM_012414 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012414.1 /DEF=Homo sapiens rab3 GTPase-activating protein, non-catalytic subunit (150kD) (RAB3-GAP150), mRNA. /FEA=mRNA /GEN=RAB3-GAP150 /PROD=rab3 GTPase-activating protein, non-catalyticsubunit (150kD) /DB_XREF=gi:6912619 /UG=Hs.197289 rab3 GTPase-activating protein, non-catalytic subunit (150kD) /FL=gb:AF255648.1 gb:AF004828.1 gb:NM_012414.1" NM_012414 aurora kinase A pseudogene 1 /// RAB3 GTPase activating protein subunit 2 (non-catalytic) AURKAPS1 /// RAB3GAP2 6791 /// 25782 NM_012414 /// NR_001587 0006886 // intracellular protein transport // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0030234 // enzyme regulator activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 202375_at NM_014822 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014822.1 /DEF=Homo sapiens SEC24 (S. cerevisiae) related gene family, member D (SEC24D), mRNA. /FEA=mRNA /GEN=SEC24D /PROD=SEC24 (S. cerevisiae) related gene family,member D /DB_XREF=gi:7662658 /UG=Hs.19822 SEC24 (S. cerevisiae) related gene family, member D /FL=gb:AB018298.1 gb:AF130464.2 gb:NM_014822.1" NM_014822 SEC24 family member D SEC24D 9871 NM_014822 /// XM_005263378 /// XM_005263379 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation 202376_at NM_001085 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001085.2 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3), mRNA. /FEA=mRNA /GEN=SERPINA3 /PROD=alpha-1-antichymotrypsin, precursor /DB_XREF=gi:9665246 /UG=Hs.234726 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 /FL=gb:BC003559.1 gb:K01500.1 gb:NM_001085.2" NM_001085 "serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3" SERPINA3 12 NM_001085 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0019216 // regulation of lipid metabolic process // non-traceable author statement /// 0030162 // regulation of proteolysis // not recorded /// 0030277 // maintenance of gastrointestinal epithelium // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202377_at AW026535 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW026535 /FEA=EST /DB_XREF=gi:5880065 /DB_XREF=est:wv14f10.x1 /CLONE=IMAGE:2529547 /UG=Hs.23581 leptin receptor gene-related protein /FL=gb:NM_017526.1 AW026535 leptin receptor overlapping transcript LEPROT 54741 NM_001198681 /// NM_001198683 /// NM_017526 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 202378_s_at NM_017526 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017526.1 /DEF=Homo sapiens leptin receptor gene-related protein (HSOBRGRP), mRNA. /FEA=mRNA /GEN=HSOBRGRP /PROD=leptin receptor gene-related protein /DB_XREF=gi:8923784 /UG=Hs.23581 leptin receptor gene-related protein /FL=gb:NM_017526.1" NM_017526 leptin receptor overlapping transcript LEPROT 54741 NM_001198681 /// NM_001198683 /// NM_017526 0046426 // negative regulation of JAK-STAT cascade // inferred from direct assay /// 0060400 // negative regulation of growth hormone receptor signaling pathway // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 202379_s_at AI361805 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI361805 /FEA=EST /DB_XREF=gi:4113426 /DB_XREF=est:qz24g07.x1 /CLONE=IMAGE:2027868 /UG=Hs.241493 natural killer-tumor recognition sequence /FL=gb:L04288.2 gb:NM_005385.2 AI361805 natural killer cell triggering receptor NKTR 4820 NM_001012651 /// NM_005385 /// XM_005265173 /// XM_005265174 /// XM_005265176 /// XM_005265178 /// XM_006713171 /// XM_006713172 /// XM_006713173 /// XM_006713174 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 202380_s_at NM_005385 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005385.2 /DEF=Homo sapiens natural killer-tumor recognition sequence (NKTR), mRNA. /FEA=mRNA /GEN=NKTR /PROD=natural killer-tumor recognition sequence /DB_XREF=gi:6631099 /UG=Hs.241493 natural killer-tumor recognition sequence /FL=gb:L04288.2 gb:NM_005385.2" NM_005385 natural killer cell triggering receptor NKTR 4820 NM_001012651 /// NM_005385 /// XM_005265173 /// XM_005265174 /// XM_005265176 /// XM_005265178 /// XM_006713171 /// XM_006713172 /// XM_006713173 /// XM_006713174 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 202381_at NM_003816 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003816.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 9 (meltrin gamma) (ADAM9), mRNA. /FEA=mRNA /GEN=ADAM9 /PROD=a disintegrin and metalloproteinase domain 9preproprotein /DB_XREF=gi:4501914 /UG=Hs.2442 a disintegrin and metalloproteinase domain 9 (meltrin gamma) /FL=gb:U41766.1 gb:NM_003816.1" NM_003816 ADAM metallopeptidase domain 9 ADAM9 8754 NM_001005845 /// NM_003816 /// NR_027638 /// NR_027639 /// NR_027878 0000186 // activation of MAPKK activity // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // inferred by curator /// 0010042 // response to manganese ion // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030216 // keratinocyte differentiation // inferred from expression pattern /// 0030574 // collagen catabolic process // traceable author statement /// 0033627 // cell adhesion mediated by integrin // inferred from mutant phenotype /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0033631 // cell-cell adhesion mediated by integrin // inferred from expression pattern /// 0034241 // positive regulation of macrophage fusion // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0042117 // monocyte activation // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from sequence or structural similarity /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from direct assay /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // traceable author statement /// 0051384 // response to glucocorticoid // inferred from sequence or structural similarity /// 0051549 // positive regulation of keratinocyte migration // inferred from mutant phenotype /// 0051592 // response to calcium ion // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0031233 // intrinsic component of external side of plasma membrane // inferred from sequence or structural similarity 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005178 // integrin binding // inferred by curator /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 202382_s_at NM_005471 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005471.1 /DEF=Homo sapiens glucosamine-6-phosphate isomerase (GNPI), mRNA. /FEA=mRNA /GEN=GNPI /PROD=glucosamine-6-phosphate isomerase /DB_XREF=gi:13027377 /UG=Hs.278500 glucosamine-6-phosphate isomerase /FL=gb:NM_005471.1 gb:AF029914.1 gb:AF048826.1 gb:D31766.1" NM_005471 glucosamine-6-phosphate deaminase 1 GNPDA1 10007 NM_005471 /// XM_005268348 /// XM_006714747 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006043 // glucosamine catabolic process // inferred from mutant phenotype /// 0006044 // N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // inferred from mutant phenotype /// 0007338 // single fertilization // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004342 // glucosamine-6-phosphate deaminase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 202383_at NM_004187 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004187.1 /DEF=Homo sapiens SMC (mouse) homolog, X chromosome (SMCX), mRNA. /FEA=mRNA /GEN=SMCX /PROD=SMC (mouse) homolog, X chromosome /DB_XREF=gi:11321604 /UG=Hs.283429 SMC (mouse) homolog, X chromosome /FL=gb:NM_004187.1 gb:L25270.1" NM_004187 lysine (K)-specific demethylase 5C KDM5C 8242 NM_001146702 /// NM_001282622 /// NM_004187 /// XM_005262035 /// XM_006724609 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0034720 // histone H3-K4 demethylation // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0001085 // RNA polymerase II transcription factor binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0032453 // histone demethylase activity (H3-K4 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 202384_s_at AW167713 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW167713 /FEA=EST /DB_XREF=gi:6399238 /DB_XREF=est:xn48b02.x1 /CLONE=IMAGE:2696907 /UG=Hs.301266 Treacher Collins-Franceschetti syndrome 1 /FL=gb:U76366.1 gb:U40847.1 gb:NM_000356.1 AW167713 Treacher Collins-Franceschetti syndrome 1 TCOF1 6949 NM_000356 /// NM_001008656 /// NM_001008657 /// NM_001135243 /// NM_001135244 /// NM_001135245 /// NM_001195141 /// XM_005268502 /// XM_005268503 /// XM_005268504 /// XM_005268505 /// XM_005268506 /// XM_005268507 /// XM_005268508 /// XM_005268509 /// XR_427778 /// XR_427779 /// XR_427780 0001501 // skeletal system development // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0042790 // transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202385_s_at NM_000356 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000356.1 /DEF=Homo sapiens Treacher Collins-Franceschetti syndrome 1 (TCOF1), mRNA. /FEA=mRNA /GEN=TCOF1 /PROD=treacle /DB_XREF=gi:4507410 /UG=Hs.301266 Treacher Collins-Franceschetti syndrome 1 /FL=gb:U76366.1 gb:U40847.1 gb:NM_000356.1" NM_000356 Treacher Collins-Franceschetti syndrome 1 TCOF1 6949 NM_000356 /// NM_001008656 /// NM_001008657 /// NM_001135243 /// NM_001135244 /// NM_001135245 /// NM_001195141 /// XM_005268502 /// XM_005268503 /// XM_005268504 /// XM_005268505 /// XM_005268506 /// XM_005268507 /// XM_005268508 /// XM_005268509 /// XR_427778 /// XR_427779 /// XR_427780 0001501 // skeletal system development // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0042790 // transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202386_s_at NM_019081 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019081.1 /DEF=Homo sapiens KIAA0430 gene product (KIAA0430), mRNA. /FEA=mRNA /GEN=KIAA0430 /PROD=hypothetical protein A-362G6.1 /DB_XREF=gi:11464998 /UG=Hs.30909 KIAA0430 gene product /FL=gb:NM_019081.1" NM_019081 KIAA0430 KIAA0430 9665 NM_001184998 /// NM_001184999 /// NM_014647 /// NM_019081 /// XM_005255704 /// XM_005255705 /// XM_005255706 /// XM_005255707 /// XM_005255708 /// XM_005255709 /// XM_006720986 /// XM_006725215 /// XM_006725216 /// XM_006725217 /// XM_006725218 /// XM_006725219 /// XM_006725220 /// XM_006725221 0006302 // double-strand break repair // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007143 // female meiotic division // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from sequence or structural similarity 0005777 // peroxisome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 202387_at NM_004323 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004323.2 /DEF=Homo sapiens BCL2-associated athanogene (BAG1), mRNA. /FEA=mRNA /GEN=BAG1 /PROD=BCL2-associated athanogene /DB_XREF=gi:7549801 /UG=Hs.41714 BCL2-associated athanogene /FL=gb:BC001936.1 gb:AF022224.1 gb:U46917.1 gb:NM_004323.2" NM_004323 BCL2-associated athanogene BAG1 573 NM_001172415 /// NM_004323 0006915 // apoptotic process // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 202388_at NM_002923 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002923.1 /DEF=Homo sapiens regulator of G-protein signalling 2, 24kD (RGS2), mRNA. /FEA=mRNA /GEN=RGS2 /PROD=regulator of G-protein signalling 2, 24kD /DB_XREF=gi:4506516 /UG=Hs.78944 regulator of G-protein signalling 2, 24kD /FL=gb:L13463.1 gb:NM_002923.1" NM_002923 regulator of G-protein signaling 2 RGS2 5997 NM_002923 0006417 // regulation of translation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010519 // negative regulation of phospholipase activity // inferred from sequence or structural similarity /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055119 // relaxation of cardiac muscle // inferred from sequence or structural similarity /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0060452 // positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0071877 // regulation of adrenergic receptor signaling pathway // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // not recorded /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // traceable author statement /// 0048487 // beta-tubulin binding // inferred from electronic annotation 202389_s_at L12392 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L12392.1 /DEF=Homo sapiens Huntingtons Disease (HD) mRNA, complete cds. /FEA=mRNA /GEN=HD /PROD=Huntingtons Disease protein /DB_XREF=gi:1709991 /UG=Hs.79391 huntingtin (Huntington disease) /FL=gb:L12392.1 gb:L20431.1 gb:NM_002111.3" L12392 huntingtin HTT 3064 NM_002111 "0000050 // urea cycle // inferred from electronic annotation /// 0000052 // citrulline metabolic process // inferred from electronic annotation /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0019244 // lactate biosynthetic process from pyruvate // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021988 // olfactory lobe development // inferred from electronic annotation /// 0021990 // neural plate formation // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0034047 // regulation of protein phosphatase type 2A activity // inferred from mutant phenotype /// 0035176 // social behavior // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048513 // organ development // not recorded /// 0048666 // neuron development // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016234 // inclusion body // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0034452 // dynactin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0045505 // dynein intermediate chain binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0050809 // diazepam binding // inferred from electronic annotation 202390_s_at NM_002111 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002111.3 /DEF=Homo sapiens huntingtin (Huntington disease) (HD), mRNA. /FEA=mRNA /GEN=HD /PROD=huntingtin /DB_XREF=gi:4755137 /UG=Hs.79391 huntingtin (Huntington disease) /FL=gb:L12392.1 gb:L20431.1 gb:NM_002111.3" NM_002111 huntingtin HTT 3064 NM_002111 "0000050 // urea cycle // inferred from electronic annotation /// 0000052 // citrulline metabolic process // inferred from electronic annotation /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007212 // dopamine receptor signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007569 // cell aging // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from electronic annotation /// 0019244 // lactate biosynthetic process from pyruvate // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021988 // olfactory lobe development // inferred from electronic annotation /// 0021990 // neural plate formation // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0034047 // regulation of protein phosphatase type 2A activity // inferred from mutant phenotype /// 0035176 // social behavior // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0046825 // regulation of protein export from nucleus // inferred from mutant phenotype /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048341 // paraxial mesoderm formation // inferred from electronic annotation /// 0048513 // organ development // not recorded /// 0048666 // neuron development // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016234 // inclusion body // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0002039 // p53 binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0034452 // dynactin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0045505 // dynein intermediate chain binding // inferred from direct assay /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0050809 // diazepam binding // inferred from electronic annotation 202391_at NM_006317 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006317.1 /DEF=Homo sapiens brain acid-soluble protein 1 (BASP1), mRNA. /FEA=mRNA /GEN=BASP1 /PROD=brain acid-soluble protein 1 /DB_XREF=gi:5453749 /UG=Hs.79516 brain abundant, membrane attached signal protein 1 /FL=gb:BC000518.1 gb:AF039656.1 gb:NM_006317.1" NM_006317 "brain abundant, membrane attached signal protein 1" BASP1 10409 NM_001271606 /// NM_006317 "0007356 // thorax and anterior abdomen determination // inferred from sequence or structural similarity /// 0008406 // gonad development // inferred from sequence or structural similarity /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060231 // mesenchymal to epithelial transition // inferred from sequence or structural similarity /// 0060421 // positive regulation of heart growth // inferred from sequence or structural similarity /// 0060539 // diaphragm development // inferred from sequence or structural similarity /// 0072075 // metanephric mesenchyme development // inferred from sequence or structural similarity /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from sequence or structural similarity /// 2001076 // positive regulation of metanephric ureteric bud development // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity 202392_s_at NM_014338 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014338.1 /DEF=Homo sapiens phosphatidylserine decarboxylase (PISD), mRNA. /FEA=mRNA /GEN=PISD /PROD=phosphatidylserine decarboxylase /DB_XREF=gi:13489111 /UG=Hs.8128 phosphatidylserine decarboxylase /FL=gb:NM_014338.1" NM_014338 microRNA 7109 /// phosphatidylserine decarboxylase MIR7109 /// PISD 23761 /// 102465666 NM_014338 /// NR_106959 /// XM_005261455 /// XM_005261456 /// XM_005261457 /// XM_005261458 /// XM_005261459 /// XM_005261460 /// XM_005261461 /// XM_005261462 /// XM_006724199 /// XM_006724200 /// XM_006724201 /// XM_006724202 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0004609 // phosphatidylserine decarboxylase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 202393_s_at NM_005655 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005655.1 /DEF=Homo sapiens TGFB inducible early growth response (TIEG), mRNA. /FEA=mRNA /GEN=TIEG /PROD=TGFB inducible early growth response /DB_XREF=gi:5032176 /UG=Hs.82173 TGFB inducible early growth response /FL=gb:U21847.1 gb:NM_005655.1" NM_005655 Kruppel-like factor 10 KLF10 7071 NM_001032282 /// NM_005655 /// NR_103759 /// NR_103760 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001501 // skeletal system development // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 1901653 // cellular response to peptide // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202394_s_at NM_018358 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018358.1 /DEF=Homo sapiens hypothetical protein FLJ11198 (FLJ11198), mRNA. /FEA=mRNA /GEN=FLJ11198 /PROD=hypothetical protein FLJ11198 /DB_XREF=gi:8922935 /UG=Hs.91251 hypothetical protein FLJ11198 /FL=gb:NM_018358.1" NM_018358 "ATP-binding cassette, sub-family F (GCN20), member 3" ABCF3 55324 NM_018358 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 202395_at NM_006178 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006178.1 /DEF=Homo sapiens N-ethylmaleimide-sensitive factor (NSF), mRNA. /FEA=mRNA /GEN=NSF /PROD=N-ethylmaleimide-sensitive factor /DB_XREF=gi:11079227 /UG=Hs.108802 N-ethylmaleimide-sensitive factor /FL=gb:AF102846.2 gb:NM_006178.1 gb:AF135168.1" NM_006178 uncharacterized LOC101930324 /// N-ethylmaleimide-sensitive factor LOC101930324 /// NSF 4905 /// 101930324 NM_006178 /// NR_040116 /// XM_006721929 /// XM_006725276 /// XM_006725626 /// XR_250612 0001921 // positive regulation of receptor recycling // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0045026 // plasma membrane fusion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from sequence or structural similarity /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 202396_at NM_006706 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006706.1 /DEF=Homo sapiens transcription factor CA150 (CA150), mRNA. /FEA=mRNA /GEN=CA150 /PROD=transcription factor CA150 /DB_XREF=gi:5729753 /UG=Hs.13063 transcription factor CA150 /FL=gb:AF017789.1 gb:NM_006706.1" NM_006706 transcription elongation regulator 1 TCERG1 10915 NM_001040006 /// NM_006706 /// XM_005268365 /// XM_005268366 /// XM_005268367 /// XM_006714754 /// XR_245850 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement" 0005634 // nucleus // inferred from electronic annotation 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from electronic annotation 202397_at NM_005796 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005796.1 /DEF=Homo sapiens nuclear transport factor 2 (placental protein 15) (PP15), mRNA. /FEA=mRNA /GEN=PP15 /PROD=nuclear transport factor 2 (placental protein15) /DB_XREF=gi:5031984 /UG=Hs.151734 nuclear transport factor 2 (placental protein 15) /FL=gb:U43939.1 gb:BC002348.1 gb:NM_005796.1" NM_005796 nuclear transport factor 2 /// nuclear transport factor 2 pseudogene 4 NUTF2 /// NUTF2P4 10204 /// 128322 NM_005796 /// XM_003960108 /// XM_005255771 /// XM_060943 0006611 // protein export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202398_at BC002785 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002785.1 /DEF=Homo sapiens, adaptor-related protein complex 3, sigma 2 subunit, clone MGC:3577, mRNA, complete cds. /FEA=mRNA /PROD=adaptor-related protein complex 3, sigma 2subunit /DB_XREF=gi:12803880 /UG=Hs.154782 adaptor-related protein complex 3, sigma 2 subunit /FL=gb:BC002785.1 gb:NM_005829.1" BC002785 "adaptor-related protein complex 3, sigma 2 subunit /// C15orf38-AP3S2 readthrough" AP3S2 /// C15orf38-AP3S2 10239 /// 100526783 NM_001199058 /// NM_005829 /// NR_023361 /// NR_037582 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0033058 // directional locomotion // inferred from mutant phenotype /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051126 // negative regulation of actin nucleation // inferred from direct assay /// 2000393 // negative regulation of lamellipodium morphogenesis // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation 202399_s_at NM_005829 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005829.1 /DEF=Homo sapiens adaptor-related protein complex 3, sigma 2 subunit (AP3S2), mRNA. /FEA=mRNA /GEN=AP3S2 /PROD=adaptor-related protein complex 3, sigma 2subunit /DB_XREF=gi:5031580 /UG=Hs.154782 adaptor-related protein complex 3, sigma 2 subunit /FL=gb:BC002785.1 gb:NM_005829.1" NM_005829 "adaptor-related protein complex 3, sigma 2 subunit /// C15orf38-AP3S2 readthrough" AP3S2 /// C15orf38-AP3S2 10239 /// 100526783 NM_001199058 /// NM_005829 /// NR_023361 /// NR_037582 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0033058 // directional locomotion // inferred from mutant phenotype /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051126 // negative regulation of actin nucleation // inferred from direct assay /// 2000393 // negative regulation of lamellipodium morphogenesis // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation 202400_s_at AI188786 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI188786 /FEA=EST /DB_XREF=gi:3739995 /DB_XREF=est:qd16g09.x1 /CLONE=IMAGE:1723936 /UG=Hs.155321 serum response factor (c-fos serum response element-binding transcription factor) /FL=gb:J03161.1 gb:NM_003131.1 AI188786 serum response factor (c-fos serum response element-binding transcription factor) SRF 6722 NM_001292001 /// NM_003131 "0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from direct assay /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003257 // positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from genetic interaction /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0009725 // response to hormone // inferred from direct assay /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030038 // contractile actin filament bundle assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0030220 // platelet formation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from mutant phenotype /// 0034097 // response to cytokine // non-traceable author statement /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045987 // positive regulation of smooth muscle contraction // inferred from direct assay /// 0046016 // positive regulation of transcription by glucose // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048666 // neuron development // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051150 // regulation of smooth muscle cell differentiation // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060947 // cardiac vascular smooth muscle cell differentiation // inferred from electronic annotation /// 0061029 // eyelid development in camera-type eye // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype /// 1900222 // negative regulation of beta-amyloid clearance // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0010736 // serum response element binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202401_s_at NM_003131 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003131.1 /DEF=Homo sapiens serum response factor (c-fos serum response element-binding transcription factor) (SRF), mRNA. /FEA=mRNA /GEN=SRF /PROD=serum response factor (c-fos serum responseelement-binding transcription factor) /DB_XREF=gi:4507204 /UG=Hs.155321 serum response factor (c-fos serum response element-binding transcription factor) /FL=gb:J03161.1 gb:NM_003131.1" NM_003131 serum response factor (c-fos serum response element-binding transcription factor) SRF 6722 NM_001292001 /// NM_003131 "0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from direct assay /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from mutant phenotype /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003257 // positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation // inferred from genetic interaction /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0009636 // response to toxic substance // traceable author statement /// 0009725 // response to hormone // inferred from direct assay /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030038 // contractile actin filament bundle assembly // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0030220 // platelet formation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0033561 // regulation of water loss via skin // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from mutant phenotype /// 0034097 // response to cytokine // non-traceable author statement /// 0035855 // megakaryocyte development // inferred from electronic annotation /// 0035912 // dorsal aorta morphogenesis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045987 // positive regulation of smooth muscle contraction // inferred from direct assay /// 0046016 // positive regulation of transcription by glucose // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048666 // neuron development // traceable author statement /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051150 // regulation of smooth muscle cell differentiation // traceable author statement /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0055003 // cardiac myofibril assembly // inferred from electronic annotation /// 0060055 // angiogenesis involved in wound healing // traceable author statement /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060947 // cardiac vascular smooth muscle cell differentiation // inferred from electronic annotation /// 0061029 // eyelid development in camera-type eye // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0090009 // primitive streak formation // inferred from electronic annotation /// 0090136 // epithelial cell-cell adhesion // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype /// 1900222 // negative regulation of beta-amyloid clearance // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0010736 // serum response element binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202402_s_at NM_001751 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001751.1 /DEF=Homo sapiens cysteinyl-tRNA synthetase (CARS), mRNA. /FEA=mRNA /GEN=CARS /PROD=cysteinyl-tRNA synthetase /DB_XREF=gi:10835050 /UG=Hs.159604 cysteinyl-tRNA synthetase /FL=gb:NM_001751.1 gb:BC002880.1 gb:AF288206.1 gb:AF288207.1" NM_001751 cysteinyl-tRNA synthetase CARS 833 NM_001014437 /// NM_001014438 /// NM_001194997 /// NM_001751 /// NM_139273 /// NR_036542 /// XM_006718340 /// XM_006718341 /// XM_006725129 /// XM_006725130 /// XR_428857 /// XR_430701 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006423 // cysteinyl-tRNA aminoacylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000049 // tRNA binding // inferred from mutant phenotype /// 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004817 // cysteine-tRNA ligase activity // inferred from direct assay /// 0004817 // cysteine-tRNA ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation 202403_s_at AA788711 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA788711 /FEA=EST /DB_XREF=gi:2848831 /DB_XREF=est:ag40g07.s1 /CLONE=IMAGE:1119324 /UG=Hs.179573 collagen, type I, alpha 2 /FL=gb:J03464.1 gb:NM_000089.1" AA788711 "collagen, type I, alpha 2" COL1A2 1278 NM_000089 0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0042476 // odontogenesis // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from direct assay /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005584 // collagen type I trimer // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay" 202404_s_at NM_000089 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000089.1 /DEF=Homo sapiens collagen, type I, alpha 2 (COL1A2), mRNA. /FEA=mRNA /GEN=COL1A2 /PROD=collagen, type I, alpha 2 /DB_XREF=gi:4502946 /UG=Hs.179573 collagen, type I, alpha 2 /FL=gb:J03464.1 gb:NM_000089.1" NM_000089 "collagen, type I, alpha 2" COL1A2 1278 NM_000089 0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0042476 // odontogenesis // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from direct assay /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005584 // collagen type I trimer // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay" 202405_at BF432532 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF432532 /FEA=EST /DB_XREF=gi:11444682 /DB_XREF=est:nac56b07.x1 /CLONE=IMAGE:3406405 /UG=Hs.182741 TIA1 cytotoxic granule-associated RNA-binding protein-like 1 /FL=gb:NM_003252.2 gb:M96954.1 BF432532 TIA1 cytotoxic granule-associated RNA binding protein-like 1 TIAL1 7073 NM_001033925 /// NM_003252 /// XM_005270108 /// XM_005270109 /// XM_005270110 /// XM_006717959 /// XR_428715 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202406_s_at NM_003252 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003252.2 /DEF=Homo sapiens TIA1 cytotoxic granule-associated RNA-binding protein-like 1 (TIAL1), transcript variant 1, mRNA. /FEA=mRNA /GEN=TIAL1 /PROD=TIA1 cytotoxic granule-associated RNA-bindingprotein-like 1, isoform 1 /DB_XREF=gi:13435392 /UG=Hs.182741 TIA1 cytotoxic granule-associated RNA-binding protein-like 1 /FL=gb:NM_003252.2 gb:M96954.1" NM_003252 TIA1 cytotoxic granule-associated RNA binding protein-like 1 TIAL1 7073 NM_001033925 /// NM_003252 /// XM_005270108 /// XM_005270109 /// XM_005270110 /// XM_006717959 /// XR_428715 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017145 // stem cell division // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202407_s_at BF342707 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF342707 /FEA=EST /DB_XREF=gi:11289729 /DB_XREF=est:602013660F1 /CLONE=IMAGE:4149542 /UG=Hs.183438 DKFZP566J153 protein /FL=gb:AL050369.1 gb:NM_015629.1 BF342707 pre-mRNA processing factor 31 PRPF31 26121 NM_015629 /// XM_005258729 /// XM_005277071 /// XM_005277249 /// XM_005278258 /// XM_006723137 /// XM_006725641 /// XM_006725767 /// XM_006725768 /// XM_006725868 /// XM_006725869 /// XM_006725956 /// XM_006725957 /// XM_006726055 /// XM_006726056 /// XM_006726153 /// XM_006726154 /// XM_006726193 /// XM_006726194 /// XM_006726273 /// XM_006726309 "0000244 // spliceosomal tri-snRNP complex assembly // inferred from direct assay /// 0000244 // spliceosomal tri-snRNP complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005684 // U2-type spliceosomal complex // inferred by curator /// 0005687 // U4 snRNP // inferred from direct assay /// 0005690 // U4atac snRNP // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070990 // snRNP binding // inferred from physical interaction 202408_s_at NM_015629 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015629.1 /DEF=Homo sapiens DKFZP566J153 protein (DKFZP566J153), mRNA. /FEA=mRNA /GEN=DKFZP566J153 /PROD=DKFZP566J153 protein /DB_XREF=gi:7661653 /UG=Hs.183438 DKFZP566J153 protein /FL=gb:AL050369.1 gb:NM_015629.1" NM_015629 pre-mRNA processing factor 31 PRPF31 26121 NM_015629 /// XM_005258729 /// XM_005277071 /// XM_005277249 /// XM_005278258 /// XM_006723137 /// XM_006725641 /// XM_006725767 /// XM_006725768 /// XM_006725868 /// XM_006725869 /// XM_006725956 /// XM_006725957 /// XM_006726055 /// XM_006726056 /// XM_006726153 /// XM_006726154 /// XM_006726193 /// XM_006726194 /// XM_006726273 /// XM_006726309 "0000244 // spliceosomal tri-snRNP complex assembly // inferred from direct assay /// 0000244 // spliceosomal tri-snRNP complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005684 // U2-type spliceosomal complex // inferred by curator /// 0005687 // U4 snRNP // inferred from direct assay /// 0005690 // U4atac snRNP // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070990 // snRNP binding // inferred from physical interaction 202409_at X07868 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:X07868 /DEF=Human DNA for insulin-like growth factor II (IGF-2); exon 7 and additional ORF /FEA=mRNA_1 /DB_XREF=gi:32998 /UG=Hs.251664 insulin-like growth factor 2 (somatomedin A) /FL=gb:BC000531.1 gb:J03242.1 gb:M17426.1 gb:NM_000612.2 X07868 insulin-like growth factor 2 (somatomedin A) /// INS-IGF2 readthrough IGF2 /// INS-IGF2 3481 /// 723961 NM_000612 /// NM_001007139 /// NM_001042376 /// NM_001127598 /// NM_001291861 /// NM_001291862 /// NR_003512 "0000165 // MAPK cascade // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0002674 // negative regulation of acute inflammatory response // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // inferred from mutant phenotype /// 0006953 // acute-phase response // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // inferred by curator /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // inferred from direct assay /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // non-traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032460 // negative regulation of protein oligomerization // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033861 // negative regulation of NAD(P)H oxidase activity // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045721 // negative regulation of gluconeogenesis // non-traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045818 // negative regulation of glycogen catabolic process // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045908 // negative regulation of vasodilation // non-traceable author statement /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0045922 // negative regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046631 // alpha-beta T cell activation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // non-traceable author statement /// 0050708 // regulation of protein secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050995 // negative regulation of lipid catabolic process // non-traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // non-traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // traceable author statement /// 0090336 // positive regulation of brown fat cell differentiation // traceable author statement /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 2000252 // negative regulation of feeding behavior // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity" 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031904 // endosome lumen // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity 202410_x_at NM_000612 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000612.2 /DEF=Homo sapiens insulin-like growth factor 2 (somatomedin A) (IGF2), mRNA. /FEA=mRNA /GEN=IGF2 /PROD=insulin-like growth factor 2 (somatomedin A) /DB_XREF=gi:6453816 /UG=Hs.251664 insulin-like growth factor 2 (somatomedin A) /FL=gb:BC000531.1 gb:J03242.1 gb:M17426.1 gb:NM_000612.2" NM_000612 insulin-like growth factor 2 (somatomedin A) /// INS-IGF2 readthrough IGF2 /// INS-IGF2 3481 /// 723961 NM_000612 /// NM_001007139 /// NM_001042376 /// NM_001127598 /// NM_001291861 /// NM_001291862 /// NR_003512 "0000165 // MAPK cascade // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002576 // platelet degranulation // traceable author statement /// 0002674 // negative regulation of acute inflammatory response // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006349 // regulation of gene expression by genetic imprinting // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // inferred from mutant phenotype /// 0006953 // acute-phase response // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // inferred by curator /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred by curator /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009314 // response to radiation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // inferred from direct assay /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030307 // positive regulation of cell growth // non-traceable author statement /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from sequence or structural similarity /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032460 // negative regulation of protein oligomerization // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from direct assay /// 0033861 // negative regulation of NAD(P)H oxidase activity // inferred from direct assay /// 0035094 // response to nicotine // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // inferred from sequence or structural similarity /// 0042060 // wound healing // inferred from electronic annotation /// 0042060 // wound healing // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043085 // positive regulation of catalytic activity // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045721 // negative regulation of gluconeogenesis // non-traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045818 // negative regulation of glycogen catabolic process // inferred from mutant phenotype /// 0045821 // positive regulation of glycolytic process // inferred from direct assay /// 0045821 // positive regulation of glycolytic process // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045908 // negative regulation of vasodilation // non-traceable author statement /// 0045909 // positive regulation of vasodilation // non-traceable author statement /// 0045922 // negative regulation of fatty acid metabolic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from direct assay /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046631 // alpha-beta T cell activation // inferred from direct assay /// 0046889 // positive regulation of lipid biosynthetic process // non-traceable author statement /// 0050708 // regulation of protein secretion // inferred from direct assay /// 0050709 // negative regulation of protein secretion // inferred from direct assay /// 0050715 // positive regulation of cytokine secretion // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050995 // negative regulation of lipid catabolic process // non-traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // non-traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060267 // positive regulation of respiratory burst // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation /// 0090277 // positive regulation of peptide hormone secretion // traceable author statement /// 0090336 // positive regulation of brown fat cell differentiation // traceable author statement /// 1902176 // negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress // non-traceable author statement /// 2000252 // negative regulation of feeding behavior // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity" 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031904 // endosome lumen // traceable author statement /// 0034774 // secretory granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // non-traceable author statement /// 0008083 // growth factor activity // inferred from direct assay /// 0030546 // receptor activator activity // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0043539 // protein serine/threonine kinase activator activity // inferred from sequence or structural similarity 202411_at NM_005532 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005532.1 /DEF=Homo sapiens interferon, alpha-inducible protein 27 (IFI27), mRNA. /FEA=mRNA /GEN=IFI27 /PROD=interferon, alpha-inducible protein 27 /DB_XREF=gi:5031780 /UG=Hs.278613 interferon, alpha-inducible protein 27 /FL=gb:NM_005532.1" NM_005532 "interferon, alpha-inducible protein 27" IFI27 3429 NM_001130080 /// NM_001288952 /// NM_001288954 /// NM_001288956 /// NM_001288957 /// NM_001288958 /// NM_001288959 /// NM_001288960 /// NM_001288995 /// NM_005532 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0097190 // apoptotic signaling pathway // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202412_s_at AW499935 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW499935 /FEA=EST /DB_XREF=gi:7112073 /DB_XREF=est:UI-HF-BN0-akf-f-02-0-UI.r1 /CLONE=IMAGE:3077114 /UG=Hs.35086 ubiquitin specific protease 1 /FL=gb:AB014458.1 gb:AF117386.1 gb:NM_003368.1 gb:AL117575.1 AW499935 ubiquitin specific peptidase 1 USP1 7398 NM_001017415 /// NM_001017416 /// NM_003368 0006281 // DNA repair // traceable author statement /// 0006282 // regulation of DNA repair // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0035520 // monoubiquitinated protein deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 202413_s_at NM_003368 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003368.1 /DEF=Homo sapiens ubiquitin specific protease 1 (USP1), mRNA. /FEA=mRNA /GEN=USP1 /PROD=ubiquitin specific protease 1 /DB_XREF=gi:4507850 /UG=Hs.35086 ubiquitin specific protease 1 /FL=gb:AB014458.1 gb:AF117386.1 gb:NM_003368.1 gb:AL117575.1" NM_003368 ubiquitin specific peptidase 1 USP1 7398 NM_001017415 /// NM_001017416 /// NM_003368 0006281 // DNA repair // traceable author statement /// 0006282 // regulation of DNA repair // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0035520 // monoubiquitinated protein deubiquitination // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 202414_at NM_000123 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000123.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) (ERCC5), mRNA. /FEA=mRNA /GEN=ERCC5 /PROD=XPG-complementing protein /DB_XREF=gi:4503600 /UG=Hs.48576 excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) /FL=gb:D16305.1 gb:L20046.1 gb:NM_000123.1" NM_000123 excision repair cross-complementation group 5 ERCC5 2073 NM_000123 "0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // inferred from mutant phenotype /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from direct assay /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0009411 // response to UV // inferred from mutant phenotype /// 0009650 // UV protection // inferred from genetic interaction /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" "0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005662 // DNA replication factor A complex // inferred from direct assay /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay" "0000405 // bubble DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // traceable author statement /// 0004520 // endodeoxyribonuclease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction" 202415_s_at NM_012267 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012267.1 /DEF=Homo sapiens hsp70-interacting protein (HSPBP1), mRNA. /FEA=mRNA /GEN=HSPBP1 /PROD=hsp70-interacting protein /DB_XREF=gi:6912423 /UG=Hs.53066 hsp70-interacting protein /FL=gb:AB020592.1 gb:AF093420.1 gb:NM_012267.1 gb:AF187859.1" NM_012267 "HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1" HSPBP1 23640 NM_001130106 /// NM_012267 /// XM_005258700 /// XM_005258701 /// XM_005258703 0006457 // protein folding // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // traceable author statement 0004857 // enzyme inhibitor activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202416_at NM_003315 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003315.1 /DEF=Homo sapiens tetratricopeptide repeat domain 2 (TTC2), mRNA. /FEA=mRNA /GEN=TTC2 /PROD=tetratricopeptide repeat domain 2 /DB_XREF=gi:4507712 /UG=Hs.5542 DnaJ (Hsp40) homolog, subfamily C, member 7 /FL=gb:U46571.1 gb:NM_003315.1" NM_003315 "DnaJ (Hsp40) homolog, subfamily C, member 7" DNAJC7 7266 NM_001144766 /// NM_003315 /// NR_029431 /// XM_006722050 /// XM_006722051 /// XM_006722052 /// XM_006722053 /// XM_006722054 0006457 // protein folding // traceable author statement /// 0070389 // chaperone cofactor-dependent protein refolding // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction 202417_at NM_012289 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012289.1 /DEF=Homo sapiens Kelch-like ECH-associated protein 1 (KIAA0132), mRNA. /FEA=mRNA /GEN=KIAA0132 /PROD=Kelch-like ECH-associated protein 1 /DB_XREF=gi:6912451 /UG=Hs.57729 Kelch-like ECH-associated protein 1 /FL=gb:BC002417.1 gb:BC002930.1 gb:D50922.1 gb:NM_012289.1" NM_012289 kelch-like ECH-associated protein 1 KEAP1 9817 NM_012289 /// NM_203500 /// XM_005260173 /// XM_005260174 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0010499 // proteasomal ubiquitin-independent protein catabolic process // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045604 // regulation of epidermal cell differentiation // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202418_at NM_020470 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020470.1 /DEF=Homo sapiens putative transmembrane protein; homolog of yeast Golgi membrane protein Yif1p (Yip1p-interacting factor) (54TM), mRNA. /FEA=mRNA /GEN=54TM /PROD=putative transmembrane protein; homolog of yeastGolgi membrane protein Yif1p (Yip1p-interacting factor) /DB_XREF=gi:9994168 /UG=Hs.5809 putative transmembrane protein; homolog of yeast Golgi membrane protein Yif1p (Yip1p-interacting factor) /FL=gb:BC001299.1 gb:AF004876.1 gb:NM_020470.1" NM_020470 Yip1 interacting factor homolog A (S. cerevisiae) YIF1A 10897 NM_020470 /// XM_005273720 /// XM_005273721 0006810 // transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202419_at NM_002035 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002035.1 /DEF=Homo sapiens follicular lymphoma variant translocation 1 (FVT1), mRNA. /FEA=mRNA /GEN=FVT1 /PROD=follicular lymphoma variant translocation 1 /DB_XREF=gi:4503816 /UG=Hs.74050 follicular lymphoma variant translocation 1 /FL=gb:NM_002035.1" NM_002035 3-ketodihydrosphingosine reductase KDSR 2531 NM_002035 /// XM_005266677 /// XM_006722433 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006666 // 3-keto-sphinganine metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047560 // 3-dehydrosphinganine reductase activity // inferred from direct assay 202420_s_at NM_001357 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001357.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) (DDX9), transcript variant 1, mRNA. /FEA=mRNA /GEN=DDX9 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9,isoform 1 /DB_XREF=gi:13514819 /UG=Hs.74578 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) /FL=gb:NM_001357.2 gb:L13848.1" NM_001357 DEAH (Asp-Glu-Ala-His) box helicase 9 DHX9 1660 NM_001357 /// NM_030588 /// NR_033302 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032508 // DNA duplex unwinding // traceable author statement /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070934 // CRD-mediated mRNA stabilization // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202421_at AB007935 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB007935.1 /DEF=Homo sapiens mRNA for KIAA0466 protein, partial cds. /FEA=mRNA /GEN=KIAA0466 /PROD=KIAA0466 protein /DB_XREF=gi:3413893 /UG=Hs.81234 immunoglobulin superfamily, member 3 /FL=gb:AF031174.1 gb:NM_001542.1" AB007935 "immunoglobulin superfamily, member 3" IGSF3 3321 NM_001007237 /// NM_001542 /// XM_005270793 /// XM_005270794 /// XM_006710593 0032808 // lacrimal gland development // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 202422_s_at NM_022977 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022977.1 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 4 (FACL4), transcript variant 2, mRNA. /FEA=mRNA /GEN=FACL4 /PROD=long-chain fatty-acid-Coenzyme A ligase 4,isoform 2 /DB_XREF=gi:12669908 /UG=Hs.81452 fatty-acid-Coenzyme A ligase, long-chain 4 /FL=gb:NM_022977.1" NM_022977 acyl-CoA synthetase long-chain family member 4 ACSL4 2182 NM_004458 /// NM_022977 /// XM_005262108 /// XM_005262109 /// XM_005262110 /// XM_006724635 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from direct assay /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from direct assay /// 0015908 // fatty acid transport // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0032307 // negative regulation of prostaglandin secretion // inferred from direct assay /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060996 // dendritic spine development // inferred from electronic annotation /// 0070672 // response to interleukin-15 // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005811 // lipid particle // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from mutant phenotype /// 0047676 // arachidonate-CoA ligase activity // inferred from direct assay 202423_at NM_006766 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006766.1 /DEF=Homo sapiens zinc finger protein 220 (ZNF220), mRNA. /FEA=mRNA /GEN=ZNF220 /PROD=zinc finger protein 220 /DB_XREF=gi:5803097 /UG=Hs.82210 zinc finger protein 220 /FL=gb:U47742.1 gb:NM_006766.1" NM_006766 K(lysine) acetyltransferase 6A KAT6A 7994 NM_001099412 /// NM_001099413 /// NM_006766 /// XM_005273649 "0003007 // heart morphogenesis // inferred from electronic annotation /// 0006323 // DNA packaging // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0090398 // cellular senescence // inferred from mutant phenotype" 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0070776 // MOZ/MORF histone acetyltransferase complex // inferred from direct assay "0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 202424_at NM_030662 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_030662.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase 2 (MAP2K2), mRNA. /FEA=mRNA /GEN=MAP2K2 /PROD=mitogen-activated protein kinase kinase 2 /DB_XREF=gi:13489053 /UG=Hs.72241 mitogen-activated protein kinase kinase 2 /FL=gb:BC000471.1 gb:NM_030662.1" NM_030662 mitogen-activated protein kinase kinase 2 MAP2K2 5605 NM_030662 /// XM_006722799 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036289 // peptidyl-serine autophosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070371 // ERK1 and ERK2 cascade // traceable author statement /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000147 // positive regulation of cell motility // inferred from electronic annotation /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay /// 0097110 // scaffold protein binding // inferred from physical interaction" 202425_x_at NM_000944 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000944.1 /DEF=Homo sapiens protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) (PPP3CA), mRNA. /FEA=mRNA /GEN=PPP3CA /PROD=protein phosphatase 3 (formerly 2B), catalyticsubunit, alpha isoform (calcineurin A alpha) /DB_XREF=gi:6715567 /UG=Hs.272458 protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) /FL=gb:J05480.1 gb:L14778.1 gb:NM_000944.1 gb:AL353950.1" NM_000944 "protein phosphatase 3, catalytic subunit, alpha isozyme" PPP3CA 5530 NM_000944 /// NM_001130691 /// NM_001130692 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202426_s_at BE675800 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE675800 /FEA=EST /DB_XREF=gi:10036341 /DB_XREF=est:7f16c05.x1 /CLONE=IMAGE:3294824 /UG=Hs.20084 retinoid X receptor, alpha /FL=gb:NM_002957.2" BE675800 "retinoid X receptor, alpha" RXRA 6256 NM_001291920 /// NM_001291921 /// NM_002957 /// XM_005263409 /// XM_006717232 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070644 // vitamin D response element binding // inferred from direct assay 202427_s_at NM_015415 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015415.1 /DEF=Homo sapiens DKFZP564B167 protein (DKFZP564B167), mRNA. /FEA=mRNA /GEN=DKFZP564B167 /PROD=DKFZP564B167 protein /DB_XREF=gi:7661601 /UG=Hs.76285 DKFZP564B167 protein /FL=gb:AL110297.1 gb:NM_015415.1" NM_015415 mitochondrial pyruvate carrier 2 MPC2 25874 NM_001143674 /// NM_015415 /// NR_026550 /// XM_006711266 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006850 // mitochondrial pyruvate transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1901475 // pyruvate transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0050833 // pyruvate transmembrane transporter activity // inferred from electronic annotation 202428_x_at NM_020548 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020548.1 /DEF=Homo sapiens diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) (DBI), mRNA. /FEA=mRNA /GEN=DBI /PROD=diazepam binding inhibitor /DB_XREF=gi:10140852 /UG=Hs.78888 diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) /FL=gb:NM_020548.1 gb:M14200.1" NM_020548 "diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)" DBI 1622 NM_001079862 /// NM_001079863 /// NM_001178017 /// NM_001178041 /// NM_001178042 /// NM_001178043 /// NM_001282633 /// NM_001282634 /// NM_001282635 /// NM_001282636 /// NM_020548 /// NR_104221 0001942 // hair follicle development // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0018345 // protein palmitoylation // inferred from direct assay /// 0036151 // phosphatidylcholine acyl-chain remodeling // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030156 // benzodiazepine receptor binding // traceable author statement /// 0036042 // long-chain fatty acyl-CoA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 202429_s_at AL353950 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AL353950.1 /DEF=Homo sapiens mRNA; cDNA DKFZp761L0516 (from clone DKFZp761L0516); complete cds. /FEA=mRNA /GEN=DKFZp761L0516 /PROD=hypothetical protein /DB_XREF=gi:7669991 /UG=Hs.272458 protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) /FL=gb:J05480.1 gb:L14778.1 gb:NM_000944.1 gb:AL353950.1" AL353950 "protein phosphatase 3, catalytic subunit, alpha isozyme" PPP3CA 5530 NM_000944 /// NM_001130691 /// NM_001130692 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202430_s_at NM_021105 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021105.1 /DEF=Homo sapiens phospholipid scramblase 1 (PLSCR1), mRNA. /FEA=mRNA /GEN=PLSCR1 /PROD=phospholipid scramblase 1 /DB_XREF=gi:10863876 /UG=Hs.198282 phospholipid scramblase 1 /FL=gb:NM_021105.1 gb:AB006746.1 gb:AF098642.1" NM_021105 phospholipid scramblase 1 PLSCR1 5359 NM_021105 /// XM_005247538 0006659 // phosphatidylserine biosynthetic process // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from direct assay /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0017121 // phospholipid scrambling // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0035456 // response to interferon-beta // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060368 // regulation of Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 2000373 // positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from direct assay /// 0017128 // phospholipid scramblase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042609 // CD4 receptor binding // inferred from physical interaction 202431_s_at NM_002467 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002467.1 /DEF=Homo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC), mRNA. /FEA=mRNA /GEN=MYC /PROD=v-myc avian myelocytomatosis viral oncogenehomolog /DB_XREF=gi:12962934 /UG=Hs.79070 v-myc avian myelocytomatosis viral oncogene homolog /FL=gb:BC000141.1 gb:BC000917.2 gb:NM_002467.1" NM_002467 v-myc avian myelocytomatosis viral oncogene homolog MYC 4609 NM_002467 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0006112 // energy reserve metabolic process // non-traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006879 // cellular iron ion homeostasis // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010332 // response to gamma radiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0032204 // regulation of telomere maintenance // inferred from mutant phenotype /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0034644 // cellular response to UV // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from expression pattern /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044346 // fibroblast apoptotic process // traceable author statement /// 0045656 // negative regulation of monocyte differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048147 // negative regulation of fibroblast proliferation // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051276 // chromosome organization // inferred from direct assay /// 0051782 // negative regulation of cell division // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0070848 // response to growth factor // traceable author statement /// 0090096 // positive regulation of metanephric cap mesenchymal cell proliferation // inferred from sequence or structural similarity /// 2000573 // positive regulation of DNA biosynthetic process // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0044195 // nucleoplasmic reticulum // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070888 // E-box binding // inferred from direct assay /// 0071074 // eukaryotic initiation factor eIF2 binding // inferred from physical interaction 202432_at NM_021132 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021132.1 /DEF=Homo sapiens protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) (PPP3CB), mRNA. /FEA=mRNA /GEN=PPP3CB /PROD=protein phosphatase 3 (formerly 2B), catalyticsubunit, beta isoform (calcineurin A beta) /DB_XREF=gi:11036639 /UG=Hs.151531 protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) /FL=gb:NM_021132.1 gb:M29551.1" NM_021132 "protein phosphatase 3, catalytic subunit, beta isozyme" PPP3CB 5532 NM_001142353 /// NM_001142354 /// NM_001289968 /// NM_001289969 /// NM_021132 /// XM_005269944 /// XM_005269945 "0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007612 // learning // traceable author statement /// 0007613 // memory // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035176 // social behavior // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042098 // T cell proliferation // non-traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // traceable author statement /// 0048675 // axon extension // traceable author statement /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from sequence or structural similarity /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005955 // calcineurin complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0030346 // protein phosphatase 2B binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from sequence or structural similarity /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202433_at NM_005827 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005827.1 /DEF=Homo sapiens UDP-galactose transporter related (UGTREL1), mRNA. /FEA=mRNA /GEN=UGTREL1 /PROD=UDP-galactose transporter related /DB_XREF=gi:5032212 /UG=Hs.154073 UDP-galactose transporter related /FL=gb:D87989.1 gb:NM_005827.1" NM_005827 "solute carrier family 35, member B1" SLC35B1 10237 NM_001278784 /// NM_005827 /// XM_005256929 /// XM_006721632 0006810 // transport // traceable author statement /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0072334 // UDP-galactose transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0005459 // UDP-galactose transmembrane transporter activity // traceable author statement 202434_s_at N21019 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N21019 /FEA=EST /DB_XREF=gi:1126189 /DB_XREF=est:yx46b08.s1 /CLONE=IMAGE:264759 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1" N21019 "cytochrome P450, family 1, subfamily B, polypeptide 1" CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation" 202435_s_at AU154504 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU154504 /FEA=EST /DB_XREF=gi:11016025 /DB_XREF=est:AU154504 /CLONE=NT2RP4001328 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1" AU154504 "cytochrome P450, family 1, subfamily B, polypeptide 1" CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation" 202436_s_at AU144855 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU144855 /FEA=EST /DB_XREF=gi:11006376 /DB_XREF=est:AU144855 /CLONE=HEMBA1003161 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1" AU144855 "cytochrome P450, family 1, subfamily B, polypeptide 1" CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation" 202437_s_at NM_000104 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000104.2 /DEF=Homo sapiens cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) (CYP1B1), mRNA. /FEA=mRNA /GEN=CYP1B1 /PROD=cytochrome P450, subfamily I (dioxin-inducible),polypeptide 1 /DB_XREF=gi:13325059 /UG=Hs.154654 cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) /FL=gb:NM_000104.2 gb:U03688.1" NM_000104 "cytochrome P450, family 1, subfamily B, polypeptide 1" CYP1B1 1545 NM_000104 0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation" 202438_x_at BF346014 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF346014 /FEA=EST /DB_XREF=gi:11293609 /DB_XREF=est:602018737F1 /CLONE=IMAGE:4154216 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) /FL=gb:M58342.1 gb:NM_000202.2 BF346014 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202439_s_at NM_000202 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000202.2 /DEF=Homo sapiens iduronate 2-sulfatase (Hunter syndrome) (IDS), transcript variant 1, mRNA. /FEA=mRNA /GEN=IDS /PROD=iduronate-2-sulfatase isoform a precursor /DB_XREF=gi:5360215 /UG=Hs.172458 iduronate 2-sulfatase (Hunter syndrome) /FL=gb:M58342.1 gb:NM_000202.2" NM_000202 iduronate 2-sulfatase IDS 3423 NM_000202 /// NM_001166550 /// NM_006123 /// NR_104128 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004423 // iduronate-2-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202440_s_at NM_005418 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005418.1 /DEF=Homo sapiens suppression of tumorigenicity 5 (ST5), mRNA. /FEA=mRNA /GEN=ST5 /PROD=suppression of tumorigenicity 5 /DB_XREF=gi:4885612 /UG=Hs.79265 suppression of tumorigenicity 5 /FL=gb:U15131.1 gb:U15779.1 gb:NM_005418.1" NM_005418 suppression of tumorigenicity 5 ST5 6764 NM_005418 /// NM_139157 /// NM_213618 /// XM_005253077 /// XM_005253079 /// XM_005253080 /// XM_005253081 /// XM_005253083 /// XM_005253084 /// XM_006718284 /// XM_006718285 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 202441_at AL568449 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL568449 /FEA=EST /DB_XREF=gi:12922799 /DB_XREF=est:AL568449 /CLONE=CS0DE001YC12 (3 prime) /UG=Hs.285818 similar to Caenorhabditis elegans protein C42C1.9 /FL=gb:AF064093.1 gb:NM_006459.1 AL568449 ER lipid raft associated 1 ERLIN1 10613 NM_001100626 /// NM_006459 /// XM_005269442 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202442_at NM_001284 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001284.1 /DEF=Homo sapiens adaptor-related protein complex 3, sigma 1 subunit (AP3S1), mRNA. /FEA=mRNA /GEN=AP3S1 /PROD=adaptor-related protein complex 3, sigma 1subunit /DB_XREF=gi:4502860 /UG=Hs.80917 adaptor-related protein complex 3, sigma 1 subunit /FL=gb:BC000804.1 gb:D63643.1 gb:U91932.1 gb:NM_001284.1" NM_001284 "adaptor-related protein complex 3, sigma 1 subunit" AP3S1 1176 NM_001002924 /// NM_001284 /// XM_005271872 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030123 // AP-3 adaptor complex // inferred from direct assay /// 0030133 // transport vesicle // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 202443_x_at AA291203 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA291203 /FEA=EST /DB_XREF=gi:1939386 /DB_XREF=est:zt38h02.s1 /CLONE=IMAGE:724659 /UG=Hs.8121 Notch (Drosophila) homolog 2 /FL=gb:AF315356.1 gb:NM_024408.1 AA291203 notch 2 NOTCH2 4853 NM_001200001 /// NM_024408 /// XM_005270901 /// XM_005270902 /// XM_006710667 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // traceable author statement /// 0001890 // placenta development // inferred from electronic annotation /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016049 // cell growth // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0030097 // hemopoiesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0046849 // bone remodeling // inferred from mutant phenotype /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072602 // interleukin-4 secretion // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0038049 // ligand-activated RNA polymerase II transcription factor binding transcription factor activity // traceable author statement 202444_s_at NM_006459 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006459.1 /DEF=Homo sapiens similar to Caenorhabditis elegans protein C42C1.9 (KEO4), mRNA. /FEA=mRNA /GEN=KEO4 /PROD=similar to Caenorhabditis elegans proteinC42C1.9 /DB_XREF=gi:5453705 /UG=Hs.285818 similar to Caenorhabditis elegans protein C42C1.9 /FL=gb:AF064093.1 gb:NM_006459.1" NM_006459 ER lipid raft associated 1 ERLIN1 10613 NM_001100626 /// NM_006459 /// XM_005269442 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202445_s_at NM_024408 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024408.1 /DEF=Homo sapiens Notch (Drosophila) homolog 2 (NOTCH2), mRNA. /FEA=mRNA /GEN=NOTCH2 /PROD=Notch (Drosophila) homolog 2 /DB_XREF=gi:13249343 /UG=Hs.8121 Notch (Drosophila) homolog 2 /FL=gb:AF315356.1 gb:NM_024408.1" NM_024408 notch 2 NOTCH2 4853 NM_001200001 /// NM_024408 /// XM_005270901 /// XM_005270902 /// XM_006710667 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001709 // cell fate determination // traceable author statement /// 0001890 // placenta development // inferred from electronic annotation /// 0002011 // morphogenesis of an epithelial sheet // inferred from electronic annotation /// 0002437 // inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // non-traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from expression pattern /// 0010467 // gene expression // traceable author statement /// 0016049 // cell growth // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0030097 // hemopoiesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from direct assay /// 0046849 // bone remodeling // inferred from mutant phenotype /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0060413 // atrial septum morphogenesis // inferred from mutant phenotype /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0072602 // interleukin-4 secretion // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0038049 // ligand-activated RNA polymerase II transcription factor binding transcription factor activity // traceable author statement 202446_s_at AI825926 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI825926 /FEA=EST /DB_XREF=gi:5446597 /DB_XREF=est:to92d05.x1 /CLONE=IMAGE:2185737 /UG=Hs.198282 phospholipid scramblase 1 /FL=gb:NM_021105.1 gb:AB006746.1 gb:AF098642.1 AI825926 phospholipid scramblase 1 PLSCR1 5359 NM_021105 /// XM_005247538 0006659 // phosphatidylserine biosynthetic process // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from direct assay /// 0006953 // acute-phase response // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0017121 // phospholipid scrambling // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0035456 // response to interferon-beta // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045089 // positive regulation of innate immune response // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060368 // regulation of Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 2000373 // positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from direct assay /// 0017128 // phospholipid scramblase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042609 // CD4 receptor binding // inferred from physical interaction 202447_at NM_001359 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001359.1 /DEF=Homo sapiens 2,4-dienoyl CoA reductase 1, mitochondrial (DECR1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=DECR1 /PROD=2,4-dienoyl CoA reductase 1 precursor /DB_XREF=gi:4503300 /UG=Hs.81548 2,4-dienoyl CoA reductase 1, mitochondrial /FL=gb:U49352.1 gb:NM_001359.1 gb:L26050.1" NM_001359 "2,4-dienoyl CoA reductase 1, mitochondrial" DECR1 1666 NM_001359 /// XM_005250808 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from direct assay /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0008670 // 2,4-dienoyl-CoA reductase (NADPH) activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // traceable author statement /// 0070402 // NADPH binding // inferred from direct assay" 202448_s_at BE675849 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE675849 /FEA=EST /DB_XREF=gi:10036390 /DB_XREF=est:7f17c03.x1 /CLONE=IMAGE:3294916 /UG=Hs.29285 ZYG homolog /FL=gb:NM_006336.1 BE675849 "zyg-11 related, cell cycle regulator" ZER1 10444 NM_006336 /// XM_005251645 /// XM_005251646 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202449_s_at NM_002957 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002957.2 /DEF=Homo sapiens retinoid X receptor, alpha (RXRA), mRNA. /FEA=mRNA /GEN=RXRA /PROD=retinoid X receptor, alpha /DB_XREF=gi:10862707 /UG=Hs.20084 retinoid X receptor, alpha /FL=gb:NM_002957.2" NM_002957 "retinoid X receptor, alpha" RXRA 6256 NM_001291920 /// NM_001291921 /// NM_002957 /// XM_005263409 /// XM_006717232 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0001893 // maternal placenta development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060038 // cardiac muscle cell proliferation // inferred from electronic annotation /// 0060528 // secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development // inferred from electronic annotation /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070644 // vitamin D response element binding // inferred from direct assay 202450_s_at NM_000396 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000396.1 /DEF=Homo sapiens cathepsin K (pycnodysostosis) (CTSK), mRNA. /FEA=mRNA /GEN=CTSK /PROD=cathepsin K (pycnodysostosis) /DB_XREF=gi:4503150 /UG=Hs.83942 cathepsin K (pycnodysostosis) /FL=gb:NM_000396.1 gb:U13665.1" NM_000396 cathepsin K CTSK 1513 NM_000396 0001957 // intramembranous ossification // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045453 // bone resorption // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction 202451_at BC000365 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000365.1 /DEF=Homo sapiens, general transcription factor IIH, polypeptide 1 (62kD subunit), clone MGC:8323, mRNA, complete cds. /FEA=mRNA /PROD=general transcription factor IIH, polypeptide 1(62kD subunit) /DB_XREF=gi:12653194 /UG=Hs.89578 general transcription factor IIH, polypeptide 1 (62kD subunit) /FL=gb:BC000365.1 gb:BC004452.1 gb:M95809.1 gb:NM_005316.1" BC000365 "general transcription factor IIH, polypeptide 1, 62kDa" GTF2H1 2965 NM_001142307 /// NM_005316 /// XM_006718208 "0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement" 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay 202452_at AI991574 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI991574 /FEA=EST /DB_XREF=gi:5838479 /DB_XREF=est:ws17h05.x1 /CLONE=IMAGE:2497497 /UG=Hs.29285 ZYG homolog /FL=gb:NM_006336.1 AI991574 "zyg-11 related, cell cycle regulator" ZER1 10444 NM_006336 /// XM_005251645 /// XM_005251646 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202453_s_at NM_005316 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005316.1 /DEF=Homo sapiens general transcription factor IIH, polypeptide 1 (62kD subunit) (GTF2H1), mRNA. /FEA=mRNA /GEN=GTF2H1 /PROD=general transcription factor IIH, polypeptide 1(62kD subunit) /DB_XREF=gi:4885364 /UG=Hs.89578 general transcription factor IIH, polypeptide 1 (62kD subunit) /FL=gb:BC000365.1 gb:BC004452.1 gb:M95809.1 gb:NM_005316.1" NM_005316 "general transcription factor IIH, polypeptide 1, 62kDa" GTF2H1 2965 NM_001142307 /// NM_005316 /// XM_006718208 "0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement" 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay 202454_s_at NM_001982 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001982.1 /DEF=Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3), mRNA. /FEA=mRNA /GEN=ERBB3 /PROD=v-erb-b2 avian erythroblastic leukemia viraloncogene homolog 3 /DB_XREF=gi:4503596 /UG=Hs.199067 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 /FL=gb:M29366.1 gb:M34309.1 gb:NM_001982.1" NM_001982 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 ERBB3 2065 NM_001005915 /// NM_001982 0003197 // endocardial cushion development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from direct assay /// 0014037 // Schwann cell differentiation // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // non-traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0051048 // negative regulation of secretion // inferred from direct assay /// 0051402 // neuron apoptotic process // inferred from mutant phenotype /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0043235 // receptor complex // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from sequence or structural similarity /// 0030296 // protein tyrosine kinase activator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction" 202455_at NM_005474 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005474.2 /DEF=Homo sapiens histone deacetylase 5 (HDAC5), mRNA. /FEA=mRNA /GEN=HDAC5 /PROD=histone deacetylase 5 /DB_XREF=gi:13259520 /UG=Hs.9028 histone deacetylase 5 /FL=gb:NM_005474.2 gb:AF132608.1" NM_005474 histone deacetylase 5 HDAC5 10014 NM_001015053 /// NM_005474 /// NM_139205 /// XM_005256904 /// XM_005256905 /// XM_005256906 /// XM_005256907 /// XM_006721629 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006342 // chromatin silencing // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010830 // regulation of myotube differentiation // inferred from sequence or structural similarity /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0016568 // chromatin modification // traceable author statement /// 0016575 // histone deacetylation // inferred from direct assay /// 0030183 // B cell differentiation // traceable author statement /// 0032869 // cellular response to insulin stimulus // non-traceable author statement /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0042113 // B cell activation // traceable author statement /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048742 // regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051153 // regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from electronic annotation /// 0070933 // histone H4 deacetylation // inferred from electronic annotation /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from mutant phenotype" 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016604 // nuclear body // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 202456_s_at NM_006336 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006336.1 /DEF=Homo sapiens ZYG homolog (ZYG), mRNA. /FEA=mRNA /GEN=ZYG /PROD=ZYG homolog /DB_XREF=gi:5454185 /UG=Hs.29285 ZYG homolog /FL=gb:NM_006336.1" NM_006336 "zyg-11 related, cell cycle regulator" ZER1 10444 NM_006336 /// XM_005251645 /// XM_005251646 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0051438 // regulation of ubiquitin-protein transferase activity // inferred from mutant phenotype 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202457_s_at AA911231 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA911231 /FEA=EST /DB_XREF=gi:3050521 /DB_XREF=est:ol49c10.s1 /CLONE=IMAGE:1526802 /UG=Hs.272458 protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) /FL=gb:J05480.1 gb:L14778.1 gb:NM_000944.1 gb:AL353950.1" AA911231 "protein phosphatase 3, catalytic subunit, alpha isozyme" PPP3CA 5530 NM_000944 /// NM_001130691 /// NM_001130692 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001915 // negative regulation of T cell mediated cytotoxicity // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0014883 // transition between fast and slow fiber // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0033173 // calcineurin-NFAT signaling cascade // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035774 // positive regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005955 // calcineurin complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // non-traceable author statement /// 0004723 // calcium-dependent protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005516 // calmodulin binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction 202458_at NM_007173 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007173.1 /DEF=Homo sapiens protease, serine, 23 (SPUVE), mRNA. /FEA=mRNA /GEN=SPUVE /PROD=protease, serine, 23 /DB_XREF=gi:6005881 /UG=Hs.325820 protease, serine, 23 /FL=gb:AL136914.1 gb:BC001278.1 gb:AF015287.1 gb:NM_007173.1 gb:AF193611.1" NM_007173 "protease, serine, 23" PRSS23 11098 NM_001293178 /// NM_001293179 /// NM_001293180 /// NM_007173 /// NR_120591 /// NR_120592 /// NR_120593 /// XM_005273727 /// XR_424260 /// XR_428964 /// XR_432738 0006508 // proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202459_s_at U55968 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:U55968 /FEA=EST /DB_XREF=gi:1354524 /DB_XREF=est:HSU55968 /CLONE=26508 /UG=Hs.166318 lipin 2 /FL=gb:D87436.1 gb:NM_014646.1 U55968 lipin 2 LPIN2 9663 NM_014646 /// XM_005258177 /// XM_005258178 /// XM_005258179 /// XM_006722368 /// XR_243814 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0008195 // phosphatidate phosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 202460_s_at NM_014646 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014646.1 /DEF=Homo sapiens lipin 2 (LPIN2), mRNA. /FEA=mRNA /GEN=LPIN2 /PROD=lipin 2 /DB_XREF=gi:7662021 /UG=Hs.166318 lipin 2 /FL=gb:D87436.1 gb:NM_014646.1" NM_014646 lipin 2 LPIN2 9663 NM_014646 /// XM_005258177 /// XM_005258178 /// XM_005258179 /// XM_006722368 /// XR_243814 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0008195 // phosphatidate phosphatase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 202461_at NM_014239 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014239.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD) (EIF2B2), mRNA. /FEA=mRNA /GEN=EIF2B2 /PROD=eukaryotic translation initiation factor 2B,subunit 2 (beta, 39kD) /DB_XREF=gi:7657057 /UG=Hs.170001 eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD) /FL=gb:BC000494.1 gb:BC003165.1 gb:AF035280.1 gb:NM_014239.1" NM_014239 "eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa" EIF2B2 8892 NM_014239 0001541 // ovarian follicle development // inferred from mutant phenotype /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // not recorded /// 0006446 // regulation of translational initiation // traceable author statement /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0019509 // L-methionine salvage from methylthioadenosine // not recorded /// 0042552 // myelination // inferred from mutant phenotype /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from mutant phenotype /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051716 // cellular response to stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0046523 // S-methyl-5-thioribose-1-phosphate isomerase activity // not recorded 202462_s_at NM_014829 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014829.1 /DEF=Homo sapiens KIAA0801 gene product (KIAA0801), mRNA. /FEA=mRNA /GEN=KIAA0801 /PROD=KIAA0801 gene product /DB_XREF=gi:7662317 /UG=Hs.17585 KIAA0801 gene product /FL=gb:AB018344.1 gb:NM_014829.1" NM_014829 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 DDX46 9879 NM_014829 /// XM_005272142 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202463_s_at NM_003926 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003926.4 /DEF=Homo sapiens methyl-CpG binding domain protein 3 (MBD3), mRNA. /FEA=mRNA /GEN=MBD3 /PROD=methyl-CpG binding domain protein 3 /DB_XREF=gi:7710147 /UG=Hs.178728 methyl-CpG binding domain protein 3 /FL=gb:BC000872.1 gb:NM_003926.4" NM_003926 methyl-CpG binding domain protein 3 MBD3 53615 NM_001281453 /// NM_001281454 /// NM_003926 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006346 // methylation-dependent chromatin silencing // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay" 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016581 // NuRD complex // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0031492 // nucleosomal DNA binding // inferred from direct assay 202464_s_at NM_004566 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004566.1 /DEF=Homo sapiens 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 3 (PFKFB3), mRNA. /FEA=mRNA /GEN=PFKFB3 /PROD=6-phosphofructo-2-kinasefructose-2,6-biphosphatase 3 /DB_XREF=gi:4758899 /UG=Hs.195471 6-phosphofructo-2-kinasefructose-2,6-biphosphatase 3 /FL=gb:D49817.1 gb:AF109735.1 gb:NM_004566.1" NM_004566 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" PFKFB3 5209 NM_001145443 /// NM_001282630 /// NM_004566 /// XM_005252463 /// XM_005252464 "0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // non-traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // non-traceable author statement /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation" 202465_at NM_002593 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002593.2 /DEF=Homo sapiens procollagen C-endopeptidase enhancer (PCOLCE), mRNA. /FEA=mRNA /GEN=PCOLCE /PROD=procollagen C-endopeptidase enhancer /DB_XREF=gi:7262388 /UG=Hs.202097 procollagen C-endopeptidase enhancer /FL=gb:BC000574.1 gb:AB008549.1 gb:L33799.1 gb:NM_002593.2" NM_002593 procollagen C-endopeptidase enhancer PCOLCE 5118 NM_002593 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from direct assay /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016504 // peptidase activator activity // inferred from direct assay 202466_at NM_006999 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006999.2 /DEF=Homo sapiens topoisomerase-related function protein 4-1 (TRF4), mRNA. /FEA=mRNA /GEN=TRF4 /PROD=topoisomerase-related function protein 4-1 /DB_XREF=gi:6631114 /UG=Hs.225951 topoisomerase-related function protein 4-1 /FL=gb:AB005754.3 gb:NM_006999.2" NM_006999 PAP associated domain containing 7 PAPD7 11044 NM_001171805 /// NM_001171806 /// NM_006999 /// XM_005248234 /// XM_005248236 /// XM_006714438 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006302 // double-strand break repair // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0004652 // polynucleotide adenylyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0043221 // SMC family protein binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202467_s_at NM_004236 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004236.1 /DEF=Homo sapiens thyroid receptor interacting protein 15 (TRIP15), mRNA. /FEA=mRNA /GEN=TRIP15 /PROD=thyroid receptor interacting protein 15 /DB_XREF=gi:4759263 /UG=Hs.30212 thyroid receptor interacting protein 15 /FL=gb:AF084260.1 gb:NM_004236.1 gb:AF120268.1 gb:AF100762.1" NM_004236 COP9 signalosome subunit 2 COPS2 9318 NM_001143887 /// NM_004236 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0010388 // cullin deneddylation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202468_s_at NM_003798 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003798.1 /DEF=Homo sapiens catenin (cadherin-associated protein), alpha-like 1 (CTNNAL1), mRNA. /FEA=mRNA /GEN=CTNNAL1 /PROD=catenin (cadherin-associated protein),alpha-like 1 /DB_XREF=gi:4503128 /UG=Hs.58488 catenin (cadherin-associated protein), alpha-like 1 /FL=gb:AF006070.1 gb:U97067.1 gb:AF080071.1 gb:AF030233.1 gb:NM_003798.1" NM_003798 "catenin (cadherin-associated protein), alpha-like 1" CTNNAL1 8727 NM_001286974 /// NM_003798 /// XM_005252291 0007155 // cell adhesion // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 202469_s_at AU149367 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU149367 /FEA=EST /DB_XREF=gi:11010888 /DB_XREF=est:AU149367 /CLONE=NT2RM4002171 /UG=Hs.64542 cleavage and polyadenylation specific factor 6, 68kD subunit /FL=gb:NM_007007.1" AU149367 "cleavage and polyadenylation specific factor 6, 68kDa" CPSF6 11052 NM_007007 /// XM_005268588 /// XM_005268589 /// XM_005268590 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202470_s_at NM_007007 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007007.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 6, 68kD subunit (CPSF6), mRNA. /FEA=mRNA /GEN=CPSF6 /PROD=cleavage and polyadenylation specific factor 6,68 kD subunit /DB_XREF=gi:5901927 /UG=Hs.64542 cleavage and polyadenylation specific factor 6, 68kD subunit /FL=gb:NM_007007.1" NM_007007 "cleavage and polyadenylation specific factor 6, 68kDa" CPSF6 11052 NM_007007 /// XM_005268588 /// XM_005268589 /// XM_005268590 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0051262 // protein tetramerization // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202471_s_at NM_004135 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004135.1 /DEF=Homo sapiens isocitrate dehydrogenase 3 (NAD+) gamma (IDH3G), mRNA. /FEA=mRNA /GEN=IDH3G /PROD=isocitrate dehydrogenase 3 (NAD+) gamma /DB_XREF=gi:4758581 /UG=Hs.75253 isocitrate dehydrogenase 3 (NAD+) gamma /FL=gb:BC001902.1 gb:BC000933.2 gb:U40272.1 gb:NM_004135.1" NM_004135 isocitrate dehydrogenase 3 (NAD+) gamma IDH3G 3421 NM_004135 /// NM_174869 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006102 // isocitrate metabolic process // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 202472_at NM_002435 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002435.1 /DEF=Homo sapiens mannose phosphate isomerase (MPI), mRNA. /FEA=mRNA /GEN=MPI /PROD=mannose-6- phosphate isomerase /DB_XREF=gi:4505234 /UG=Hs.75694 mannose phosphate isomerase /FL=gb:NM_002435.1" NM_002435 mannose phosphate isomerase MPI 4351 NM_001289155 /// NM_001289156 /// NM_001289157 /// NM_002435 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0009298 // GDP-mannose biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004476 // mannose-6-phosphate isomerase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202473_x_at AA703045 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA703045 /FEA=EST /DB_XREF=gi:2706158 /DB_XREF=est:zi74d09.s1 /CLONE=IMAGE:436529 /UG=Hs.83634 host cell factor C1 (VP16-accessory protein) /FL=gb:NM_005334.1 AA703045 host cell factor C1 HCFC1 3054 NM_005334 /// XM_005274664 /// XM_006724815 /// XM_006724816 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006325 // chromatin organization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019046 // release from viral latency // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045787 // positive regulation of cell cycle // traceable author statement /// 0050821 // protein stabilization // inferred from direct assay" 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0070461 // SAGA-type complex // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 202474_s_at NM_005334 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005334.1 /DEF=Homo sapiens host cell factor C1 (VP16-accessory protein) (HCFC1), mRNA. /FEA=mRNA /GEN=HCFC1 /PROD=host cell factor C1 (VP16-accessory protein) /DB_XREF=gi:4885402 /UG=Hs.83634 host cell factor C1 (VP16-accessory protein) /FL=gb:NM_005334.1" NM_005334 host cell factor C1 HCFC1 3054 NM_005334 /// XM_005274664 /// XM_006724815 /// XM_006724816 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006325 // chromatin organization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019046 // release from viral latency // non-traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043254 // regulation of protein complex assembly // inferred from direct assay /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay /// 0045787 // positive regulation of cell cycle // traceable author statement /// 0050821 // protein stabilization // inferred from direct assay" 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048188 // Set1C/COMPASS complex // inferred from direct assay /// 0070461 // SAGA-type complex // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 202475_at NM_006326 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006326.1 /DEF=Homo sapiens seven transmembrane domain protein (NIFIE14), mRNA. /FEA=mRNA /GEN=NIFIE14 /PROD=seven transmembrane domain protein /DB_XREF=gi:5453781 /UG=Hs.9234 seven transmembrane domain protein /FL=gb:BC001118.1 gb:NM_006326.1" NM_006326 transmembrane protein 147 TMEM147 10430 NM_001242597 /// NM_001242598 /// NM_032635 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202476_s_at BF002130 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF002130 /FEA=EST /DB_XREF=gi:10702405 /DB_XREF=est:7g99f03.x1 /CLONE=IMAGE:3314621 /UG=Hs.13386 gamma-tubulin complex protein 2 /FL=gb:BC005011.1 gb:AF042379.1 gb:NM_006659.1 BF002130 "tubulin, gamma complex associated protein 2" TUBGCP2 10844 NM_001256617 /// NM_001256618 /// NM_006659 /// NR_046330 /// XM_006717596 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202477_s_at NM_006659 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006659.1 /DEF=Homo sapiens gamma-tubulin complex protein 2 (GCP2), mRNA. /FEA=mRNA /GEN=GCP2 /PROD=gamma-tubulin complex protein 2 /DB_XREF=gi:5729839 /UG=Hs.13386 gamma-tubulin complex protein 2 /FL=gb:BC005011.1 gb:AF042379.1 gb:NM_006659.1" NM_006659 "tubulin, gamma complex associated protein 2" TUBGCP2 10844 NM_001256617 /// NM_001256618 /// NM_006659 /// NR_046330 /// XM_006717596 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // traceable author statement /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202478_at NM_021643 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021643.1 /DEF=Homo sapiens GS3955 protein (GS3955), mRNA. /FEA=mRNA /GEN=GS3955 /PROD=GS3955 protein /DB_XREF=gi:11056053 /UG=Hs.155418 GS3955 protein /FL=gb:NM_021643.1 gb:BC002637.1 gb:D87119.1" NM_021643 tribbles pseudokinase 2 TRIB2 28951 NM_021643 /// NR_027303 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043405 // regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045081 // negative regulation of interleukin-10 biosynthetic process // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation "0000166 // nucleotide binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0055106 // ubiquitin-protein transferase regulator activity // inferred from sequence or structural similarity" 202479_s_at BC002637 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002637.1 /DEF=Homo sapiens, GS3955 protein, clone MGC:3860, mRNA, complete cds. /FEA=mRNA /PROD=GS3955 protein /DB_XREF=gi:12803604 /UG=Hs.155418 GS3955 protein /FL=gb:NM_021643.1 gb:BC002637.1 gb:D87119.1" BC002637 tribbles pseudokinase 2 TRIB2 28951 NM_021643 /// NR_027303 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043405 // regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045081 // negative regulation of interleukin-10 biosynthetic process // inferred from mutant phenotype /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation "0000166 // nucleotide binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0055106 // ubiquitin-protein transferase regulator activity // inferred from sequence or structural similarity" 202480_s_at NM_004216 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004216.1 /DEF=Homo sapiens death effector domain-containing (DEDD), mRNA. /FEA=mRNA /GEN=DEDD /PROD=death effector domain-containing /DB_XREF=gi:4758143 /UG=Hs.169681 death effector domain-containing /FL=gb:AF083236.1 gb:AF043733.1 gb:AF100341.1 gb:NM_004216.1" NM_004216 death effector domain containing DEDD 9191 NM_001039711 /// NM_001039712 /// NM_004216 /// NM_032998 /// XM_005245597 /// XM_005245598 /// XM_005245599 /// XM_005245600 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 1901837 // negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202481_at NM_004753 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004753.1 /DEF=Homo sapiens short-chain dehydrogenasereductase 1 (SDR1), mRNA. /FEA=mRNA /GEN=SDR1 /PROD=short-chain dehydrogenasereductase 1 /DB_XREF=gi:4759083 /UG=Hs.17144 short-chain dehydrogenasereductase 1 /FL=gb:BC002730.1 gb:AF061741.1 gb:NM_004753.1" NM_004753 dehydrogenase/reductase (SDR family) member 3 DHRS3 9249 NM_004753 /// XM_005263533 /// XM_005263534 /// XM_006711036 "0001523 // retinoid metabolic process // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042572 // retinol metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // traceable author statement 0000166 // nucleotide binding // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0052650 // NADP-retinol dehydrogenase activity // inferred from electronic annotation 202482_x_at AI862473 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI862473 /FEA=EST /DB_XREF=gi:5526580 /DB_XREF=est:td16h04.x1 /CLONE=IMAGE:2075863 /UG=Hs.24763 RAN binding protein 1 /FL=gb:D38076.1 gb:NM_002882.2 AI862473 RAN binding protein 1 RANBP1 5902 NM_001278639 /// NM_001278640 /// NM_001278641 /// NM_002882 /// XM_006724287 /// XM_006724288 0007051 // spindle organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046604 // positive regulation of mitotic centrosome separation // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement 202483_s_at NM_002882 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002882.2 /DEF=Homo sapiens RAN binding protein 1 (RANBP1), mRNA. /FEA=mRNA /GEN=RANBP1 /PROD=RAN binding protein 1 /DB_XREF=gi:6382077 /UG=Hs.24763 RAN binding protein 1 /FL=gb:D38076.1 gb:NM_002882.2" NM_002882 RAN binding protein 1 RANBP1 5902 NM_001278639 /// NM_001278640 /// NM_001278641 /// NM_002882 /// XM_006724287 /// XM_006724288 0007051 // spindle organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046604 // positive regulation of mitotic centrosome separation // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement 202484_s_at AF072242 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF072242.1 /DEF=Homo sapiens methyl-CpG binding protein MBD2 (MBD2) mRNA, complete cds. /FEA=mRNA /GEN=MBD2 /PROD=methyl-CpG binding protein MBD2 /DB_XREF=gi:3800792 /UG=Hs.25674 methyl-CpG binding domain protein 2 /FL=gb:AF072242.1 gb:NM_003927.2" AF072242 methyl-CpG binding domain protein 2 MBD2 8932 NM_003927 /// NM_015832 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement" 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035197 // siRNA binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202485_s_at NM_003927 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003927.2 /DEF=Homo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 1, mRNA. /FEA=mRNA /GEN=MBD2 /PROD=methyl-CpG binding domain protein 2, isoform 1 /DB_XREF=gi:7710146 /UG=Hs.25674 methyl-CpG binding domain protein 2 /FL=gb:AF072242.1 gb:NM_003927.2" NM_003927 methyl-CpG binding domain protein 2 MBD2 8932 NM_003927 /// NM_015832 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement" 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0000785 // chromatin // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003696 // satellite DNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008327 // methyl-CpG binding // inferred from direct assay /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035197 // siRNA binding // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 202486_at NM_006796 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006796.1 /DEF=Homo sapiens AFG3 (ATPase family gene 3, yeast)-like 2 (AFG3L2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=AFG3L2 /PROD=AFG3-like 2 /DB_XREF=gi:5802969 /UG=Hs.29385 AFG3 (ATPase family gene 3, yeast)-like 2 /FL=gb:NM_006796.1" NM_006796 AFG3-like AAA ATPase 2 AFG3L2 10939 NM_006796 0006508 // proteolysis // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0016265 // death // inferred from electronic annotation /// 0021675 // nerve development // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0034982 // mitochondrial protein processing // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042407 // cristae formation // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 202487_s_at NM_012412 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012412.1 /DEF=Homo sapiens purine-rich element binding protein B (PURB), mRNA. /FEA=mRNA /GEN=PURB /PROD=purine-rich element binding protein B /DB_XREF=gi:6912615 /UG=Hs.301005 purine-rich element binding protein B /FL=gb:BC000098.1 gb:BC004274.1 gb:AF081192.1 gb:NM_012412.1" NM_012412 "H2A histone family, member V" H2AFV 94239 NM_012412 /// NM_138635 /// NM_201436 /// NM_201516 /// NM_201517 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202488_s_at NM_005971 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005971.2 /DEF=Homo sapiens FXYD domain-containing ion transport regulator 3 (FXYD3), transcript variant 1, mRNA. /FEA=mRNA /GEN=FXYD3 /PROD=MAT-8 protein, isoform 1 precursor /DB_XREF=gi:11612675 /UG=Hs.301350 FXYD domain-containing ion transport regulator 3 /FL=gb:NM_005971.2 gb:BC005238.1" NM_005971 FXYD domain containing ion transport regulator 3 FXYD3 5349 NM_001136007 /// NM_001136008 /// NM_001136009 /// NM_001136010 /// NM_001136011 /// NM_001136012 /// NM_005971 /// NM_021910 /// XM_005258992 /// XM_005258993 /// XM_005258994 /// XM_005258995 /// XM_005258996 /// XM_006723242 /// XM_006723243 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 202489_s_at BC005238 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005238.1 /DEF=Homo sapiens, FXYD domain-containing ion transport regulator 3, clone MGC:12265, mRNA, complete cds. /FEA=mRNA /PROD=FXYD domain-containing ion transport regulator3 /DB_XREF=gi:13528881 /UG=Hs.301350 FXYD domain-containing ion transport regulator 3 /FL=gb:NM_005971.2 gb:BC005238.1" BC005238 FXYD domain containing ion transport regulator 3 FXYD3 5349 NM_001136007 /// NM_001136008 /// NM_001136009 /// NM_001136010 /// NM_001136011 /// NM_001136012 /// NM_005971 /// NM_021910 /// XM_005258992 /// XM_005258993 /// XM_005258994 /// XM_005258995 /// XM_005258996 /// XM_006723242 /// XM_006723243 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005216 // ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from electronic annotation 202490_at AF153419 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF153419.2 /DEF=Homo sapiens IkappaBkinase complex-associated protein (IKBKAP) mRNA, complete cds. /FEA=mRNA /GEN=IKBKAP /PROD=IkappaBkinase complex-associated protein /DB_XREF=gi:13133509 /UG=Hs.31323 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein /FL=gb:AF153419.2 gb:AF044195.1 gb:NM_003640.1" AF153419 "inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" IKBKAP 8518 NM_003640 /// XM_005252285 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0045859 // regulation of protein kinase activity // traceable author statement" "0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay" 0003677 // DNA binding // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008607 // phosphorylase kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation 202491_s_at NM_003640 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003640.1 /DEF=Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), mRNA. /FEA=mRNA /GEN=IKBKAP /PROD=inhibitor of kappa light polypeptide geneenhancer in B-cells, kinase complex-associated protein /DB_XREF=gi:4504628 /UG=Hs.31323 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein /FL=gb:AF153419.2 gb:AF044195.1 gb:NM_003640.1" NM_003640 "inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein" IKBKAP 8518 NM_003640 /// XM_005252285 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0045859 // regulation of protein kinase activity // traceable author statement" "0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay" 0003677 // DNA binding // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008607 // phosphorylase kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation 202492_at NM_024085 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024085.1 /DEF=Homo sapiens hypothetical protein FLJ22169 (FLJ22169), mRNA. /FEA=mRNA /GEN=FLJ22169 /PROD=hypothetical protein FLJ22169 /DB_XREF=gi:13129081 /UG=Hs.323363 hypothetical protein FLJ22169 /FL=gb:BC001206.1 gb:NM_024085.1" NM_024085 autophagy related 9A ATG9A 79065 NM_001077198 /// NM_024085 /// NR_104255 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000422 // mitochondrion degradation // not recorded /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from direct assay /// 0015886 // heme transport // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from electronic annotation /// 0034497 // protein localization to pre-autophagosomal structure // not recorded /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0043588 // skin development // inferred from mutant phenotype /// 0044805 // late nucleophagy // not recorded /// 0045087 // innate immune response // inferred from electronic annotation /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // /// 0055085 // transmembrane transport // inferred from electronic annotation 0000407 // pre-autophagosomal structure // not recorded /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005776 // autophagic vacuole // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // not recorded /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015002 // heme-copper terminal oxidase activity // inferred from electronic annotation /// 0015232 // heme transporter activity // traceable author statement /// 0015439 // heme-transporting ATPase activity // inferred from mutant phenotype /// 0015562 // efflux transmembrane transporter activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation" 202493_x_at NM_001317 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001317.2 /DEF=Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 1, mRNA. /FEA=mRNA /GEN=CSH1 /PROD=chorionic somatomammotropin hormone 1, isoform 1precursor /DB_XREF=gi:12408683 /UG=Hs.324928 chorionic somatomammotropin hormone 1 (placental lactogen) /FL=gb:NM_001317.2 gb:J00118.1" NM_001317 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 CSH1 /// CSHL1 /// GH1 1442 /// 1444 /// 2688 NM_000515 /// NM_001317 /// NM_001318 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202494_at NM_006112 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006112.1 /DEF=Homo sapiens peptidylprolyl isomerase E (cyclophilin E) (PPIE), mRNA. /FEA=mRNA /GEN=PPIE /PROD=peptidylprolyl isomerase E (cyclophilin E) /DB_XREF=gi:5174636 /UG=Hs.33251 peptidylprolyl isomerase E (cyclophilin E) /FL=gb:BC004898.1 gb:AF042385.1 gb:AF104012.1 gb:NM_006112.1" NM_006112 peptidylprolyl isomerase E (cyclophilin E) PPIE 10450 NM_001195007 /// NM_006112 /// NM_203456 /// NM_203457 /// NR_036543 /// NR_036544 /// XM_006710288 /// XM_006710289 /// XM_006710290 /// XM_006710291 /// XM_006710292 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0000413 // protein peptidyl-prolyl isomerization // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202495_at NM_003192 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003192.1 /DEF=Homo sapiens tubulin-specific chaperone c (TBCC), mRNA. /FEA=mRNA /GEN=TBCC /PROD=beta-tubulin cofactor C /DB_XREF=gi:4507372 /UG=Hs.75064 tubulin-specific chaperone c /FL=gb:U61234.1 gb:NM_003192.1" NM_003192 tubulin folding cofactor C TBCC 6903 NM_003192 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // traceable author statement /// 0032391 // photoreceptor connecting cilium // inferred from direct assay 0003924 // GTPase activity // inferred from direct assay /// 0051087 // chaperone binding // traceable author statement 202496_at NM_014329 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014329.1 /DEF=Homo sapiens autoantigen (RCD-8), mRNA. /FEA=mRNA /GEN=RCD-8 /PROD=autoantigen /DB_XREF=gi:7657509 /UG=Hs.75682 autoantigen /FL=gb:L26339.1 gb:U17474.1 gb:NM_014329.1" NM_014329 enhancer of mRNA decapping 4 EDC4 23644 NM_014329 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement" 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202497_x_at AI631159 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI631159 /FEA=EST /DB_XREF=gi:4682489 /DB_XREF=est:ts93d05.x1 /CLONE=IMAGE:2238825 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 /FL=gb:M20681.1 gb:NM_006931.1" AI631159 "solute carrier family 2 (facilitated glucose transporter), member 3" SLC2A3 6515 NM_006931 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 202498_s_at BE550486 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE550486 /FEA=EST /DB_XREF=gi:9792178 /DB_XREF=est:7a27c01.x1 /CLONE=IMAGE:3219936 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 /FL=gb:M20681.1 gb:NM_006931.1" BE550486 "solute carrier family 2 (facilitated glucose transporter), member 3" SLC2A3 6515 NM_006931 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 202499_s_at NM_006931 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006931.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 3 (SLC2A3), mRNA. /FEA=mRNA /GEN=SLC2A3 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 3 /DB_XREF=gi:5902089 /UG=Hs.7594 solute carrier family 2 (facilitated glucose transporter), member 3 /FL=gb:M20681.1 gb:NM_006931.1" NM_006931 "solute carrier family 2 (facilitated glucose transporter), member 3" SLC2A3 6515 NM_006931 0005975 // carbohydrate metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0019852 // L-ascorbic acid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0022857 // transmembrane transporter activity // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 202500_at NM_006736 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006736.1 /DEF=Homo sapiens heat shock protein, neuronal DNAJ-like 1 (HSJ1), mRNA. /FEA=mRNA /GEN=HSJ1 /PROD=heat shock protein, neuronal DNAJ-like 1 /DB_XREF=gi:5921580 /UG=Hs.77768 DnaJ (Hsp40) homolog, subfamily B, member 2 /FL=gb:NM_006736.1" NM_006736 "DnaJ (Hsp40) homolog, subfamily B, member 2" DNAJB2 3300 NM_001039550 /// NM_006736 0006457 // protein folding // traceable author statement /// 0006986 // response to unfolded protein // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from genetic interaction /// 0030308 // negative regulation of cell growth // inferred from genetic interaction /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 0090086 // negative regulation of protein deubiquitination // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0031593 // polyubiquitin binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 202501_at NM_014268 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014268.1 /DEF=Homo sapiens microtubule-associated protein, RPEB family, member 2 (MAPRE2), mRNA. /FEA=mRNA /GEN=MAPRE2 /PROD=microtubule-associated protein, RPEB family,member 2 /DB_XREF=gi:10346134 /UG=Hs.78335 microtubule-associated protein, RPEB family, member 2 /FL=gb:NM_014268.1" NM_014268 "microtubule-associated protein, RP/EB family, member 2" MAPRE2 10982 NM_001143826 /// NM_001143827 /// NM_001256420 /// NM_014268 /// NR_046177 /// XM_006722375 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 202502_at NM_000016 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000016.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain (ACADM), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADM /PROD=acyl-Coenzyme A dehydrogenase, C-4 to C-12straight chain proenzyme /DB_XREF=gi:4557230 /UG=Hs.79158 acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain /FL=gb:BC005377.1 gb:M16827.1 gb:NM_000016.1 gb:AF251043.1" NM_000016 "acyl-CoA dehydrogenase, C-4 to C-12 straight chain" ACADM 34 NM_000016 /// NM_001127328 /// NM_001286042 /// NM_001286043 /// NM_001286044 /// NR_022013 "0001889 // liver development // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0006082 // organic acid metabolic process // inferred from electronic annotation /// 0006111 // regulation of gluconeogenesis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from mutant phenotype /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019254 // carnitine metabolic process, CoA-linked // inferred from mutant phenotype /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from direct assay /// 0033539 // fatty acid beta-oxidation using acyl-CoA dehydrogenase // inferred from mutant phenotype /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045329 // carnitine biosynthetic process // inferred from mutant phenotype /// 0051791 // medium-chain fatty acid metabolic process // inferred from direct assay /// 0051793 // medium-chain fatty acid catabolic process // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0030424 // axon // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003995 // acyl-CoA dehydrogenase activity // inferred from direct assay /// 0003995 // acyl-CoA dehydrogenase activity // inferred from mutant phenotype /// 0003995 // acyl-CoA dehydrogenase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0070991 // medium-chain-acyl-CoA dehydrogenase activity // inferred from direct assay" 202503_s_at NM_014736 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014736.1 /DEF=Homo sapiens KIAA0101 gene product (KIAA0101), mRNA. /FEA=mRNA /GEN=KIAA0101 /PROD=KIAA0101 gene product /DB_XREF=gi:7661905 /UG=Hs.81892 KIAA0101 gene product /FL=gb:D14657.1 gb:NM_014736.1" NM_014736 KIAA0101 KIAA0101 9768 NM_001029989 /// NM_014736 /// NR_109934 0006260 // DNA replication // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0019985 // translesion synthesis // inferred from mutant phenotype /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202504_at NM_012101 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012101.1 /DEF=Homo sapiens ataxia-telangiectasia group D-associated protein (ATDC), mRNA. /FEA=mRNA /GEN=ATDC /PROD=ataxia-telangiectasia group D-associatedprotein /DB_XREF=gi:6912249 /UG=Hs.82237 ataxia-telangiectasia group D-associated protein /FL=gb:AF230388.1 gb:L24203.1 gb:NM_012101.1" NM_012101 tripartite motif containing 29 TRIM29 23650 NM_012101 /// NM_058193 /// XM_005271487 /// XM_005271490 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 1900181 // negative regulation of protein localization to nucleus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0002039 // p53 binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202505_at NM_003092 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003092.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide B (SNRPB2), mRNA. /FEA=mRNA /GEN=SNRPB2 /PROD=small nuclear ribonucleoprotein polypeptide B /DB_XREF=gi:4507122 /UG=Hs.82575 small nuclear ribonucleoprotein polypeptide B /FL=gb:M15841.1 gb:NM_003092.1" NM_003092 small nuclear ribonucleoprotein polypeptide B SNRPB2 6629 NM_003092 /// NM_198220 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005686 // U2 snRNP // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from electronic annotation 202506_at NM_006751 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006751.1 /DEF=Homo sapiens sperm specific antigen 2 (SSFA2), mRNA. /FEA=mRNA /GEN=SSFA2 /PROD=sperm specific antigen 2 /DB_XREF=gi:5803178 /UG=Hs.82767 sperm specific antigen 2 /FL=gb:M61199.1 gb:NM_006751.1" NM_006751 sperm specific antigen 2 SSFA2 6744 NM_001130445 /// NM_001287503 /// NM_001287504 /// NM_001287505 /// NM_006751 /// NR_109843 /// XM_005246812 /// XM_005246813 /// XR_241319 /// XR_241320 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation 202507_s_at L19760 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L19760.1 /DEF=Human nerve-terminal protein (isoform SNAP25A) mRNA, complete cds. /FEA=mRNA /GEN=SNAP /PROD=nerve terminal protein /DB_XREF=gi:307425 /UG=Hs.84389 synaptosomal-associated protein, 25kD /FL=gb:D21267.1 gb:L19760.1 gb:L19761.1 gb:NM_003081.1" L19760 "synaptosomal-associated protein, 25kDa" SNAP25 6616 NM_003081 /// NM_130811 /// XM_005260808 /// XM_005260810 /// XM_006723614 0001504 // neurotransmitter uptake // non-traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016081 // synaptic vesicle docking involved in exocytosis // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202508_s_at NM_003081 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003081.1 /DEF=Homo sapiens synaptosomal-associated protein, 25kD (SNAP25), mRNA. /FEA=mRNA /GEN=SNAP25 /PROD=synaptosomal-associated protein (25kD) /DB_XREF=gi:4507098 /UG=Hs.84389 synaptosomal-associated protein, 25kD /FL=gb:D21267.1 gb:L19760.1 gb:L19761.1 gb:NM_003081.1" NM_003081 "synaptosomal-associated protein, 25kDa" SNAP25 6616 NM_003081 /// NM_130811 /// XM_005260808 /// XM_005260810 /// XM_006723614 0001504 // neurotransmitter uptake // non-traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007268 // synaptic transmission // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016081 // synaptic vesicle docking involved in exocytosis // non-traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070032 // synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202509_s_at AI862445 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI862445 /FEA=EST /DB_XREF=gi:5526552 /DB_XREF=est:td16e10.x1 /CLONE=IMAGE:2075850 /UG=Hs.101382 tumor necrosis factor, alpha-induced protein 2 /FL=gb:M92357.1 gb:NM_006291.1" AI862445 "tumor necrosis factor, alpha-induced protein 2" TNFAIP2 7127 NM_006291 /// XM_006720243 0001525 // angiogenesis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000145 // exocyst // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 202510_s_at NM_006291 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006291.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 2 (TNFAIP2), mRNA. /FEA=mRNA /GEN=TNFAIP2 /PROD=tumor necrosis factor, alpha-induced protein 2 /DB_XREF=gi:5454133 /UG=Hs.101382 tumor necrosis factor, alpha-induced protein 2 /FL=gb:M92357.1 gb:NM_006291.1" NM_006291 "tumor necrosis factor, alpha-induced protein 2" TNFAIP2 7127 NM_006291 /// XM_006720243 0001525 // angiogenesis // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0000145 // exocyst // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 202511_s_at AK001899 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK001899.1 /DEF=Homo sapiens cDNA FLJ11037 fis, clone PLACE1004316, highly similar to H.sapiens mRNA for apoptosis specific protein. /FEA=mRNA /DB_XREF=gi:7023451 /UG=Hs.11171 APG5 (autophagy 5, S. cerevisiae)-like /FL=gb:NM_004849.1" AK001899 autophagy related 5 ATG5 9474 NM_001286106 /// NM_001286107 /// NM_001286108 /// NM_001286111 /// NM_004849 /// NR_104402 /// NR_104403 0000045 // autophagic vacuole assembly // not recorded /// 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // not recorded /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002739 // regulation of cytokine secretion involved in immune response // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // not recorded /// 0006914 // autophagy // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0030435 // sporulation resulting in formation of a cellular spore // not recorded /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from sequence or structural similarity /// 0044805 // late nucleophagy // not recorded /// 0045087 // innate immune response // traceable author statement /// 0048840 // otolith development // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // not recorded /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // not recorded 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // not recorded 202512_s_at NM_004849 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004849.1 /DEF=Homo sapiens APG5 (autophagy 5, S. cerevisiae)-like (APG5L), mRNA. /FEA=mRNA /GEN=APG5L /PROD=APG5 (autophagy 5, S. cerevisiae)-like /DB_XREF=gi:4757797 /UG=Hs.11171 APG5 (autophagy 5, S. cerevisiae)-like /FL=gb:NM_004849.1" NM_004849 autophagy related 5 ATG5 9474 NM_001286106 /// NM_001286107 /// NM_001286108 /// NM_001286111 /// NM_004849 /// NR_104402 /// NR_104403 0000045 // autophagic vacuole assembly // not recorded /// 0000045 // autophagic vacuole assembly // inferred from sequence or structural similarity /// 0000422 // mitochondrion degradation // not recorded /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002739 // regulation of cytokine secretion involved in immune response // inferred from electronic annotation /// 0006501 // C-terminal protein lipidation // not recorded /// 0006914 // autophagy // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0030435 // sporulation resulting in formation of a cellular spore // not recorded /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from sequence or structural similarity /// 0044805 // late nucleophagy // not recorded /// 0045087 // innate immune response // traceable author statement /// 0048840 // otolith development // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 1902017 // regulation of cilium assembly // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005776 // autophagic vacuole // inferred from direct assay /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0034045 // pre-autophagosomal structure membrane // not recorded /// 0034045 // pre-autophagosomal structure membrane // inferred from sequence or structural similarity /// 0034274 // Atg12-Atg5-Atg16 complex // not recorded 0005515 // protein binding // inferred from physical interaction /// 0019776 // Atg8 ligase activity // not recorded 202513_s_at NM_006245 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006245.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), delta isoform (PPP2R5D), mRNA. /FEA=mRNA /GEN=PPP2R5D /PROD=protein phosphatase 2, regulatory subunit B(B56), delta isoform /DB_XREF=gi:5453953 /UG=Hs.118244 protein phosphatase 2, regulatory subunit B (B56), delta isoform /FL=gb:BC001095.1 gb:L76702.1 gb:AB000634.1 gb:NM_006245.1" NM_006245 "protein phosphatase 2, regulatory subunit B', delta" PPP2R5D 5528 NM_001270476 /// NM_006245 /// NM_180976 /// NM_180977 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006096 // glycolytic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0016311 // dephosphorylation // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation 202514_at AW139131 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW139131 /FEA=EST /DB_XREF=gi:6143449 /DB_XREF=est:UI-H-BI1-aet-a-12-0-UI.s1 /CLONE=IMAGE:2720183 /UG=Hs.154294 discs, large (Drosophila) homolog 1 /FL=gb:NM_004087.1 gb:U13896.1" AW139131 "discs, large homolog 1 (Drosophila)" DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 202515_at BG251175 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG251175 /FEA=EST /DB_XREF=gi:12760991 /DB_XREF=est:602364982F1 /CLONE=IMAGE:4473165 /UG=Hs.154294 discs, large (Drosophila) homolog 1 /FL=gb:NM_004087.1 gb:U13896.1" BG251175 "discs, large homolog 1 (Drosophila)" DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 202516_s_at NM_004087 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004087.1 /DEF=Homo sapiens discs, large (Drosophila) homolog 1 (DLG1), mRNA. /FEA=mRNA /GEN=DLG1 /PROD=discs, large (Drosophila) homolog 1 /DB_XREF=gi:4758161 /UG=Hs.154294 discs, large (Drosophila) homolog 1 /FL=gb:NM_004087.1 gb:U13896.1" NM_004087 "discs, large homolog 1 (Drosophila)" DLG1 1739 NM_001098424 /// NM_001204386 /// NM_001204387 /// NM_001204388 /// NM_001290983 /// NM_004087 /// XM_005269289 /// XM_005269290 /// XM_005269291 /// XM_005269292 /// XM_005269297 /// XM_005269298 /// XM_005269299 /// XM_005269301 /// XM_006713520 /// XM_006713521 /// XR_246039 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001771 // immunological synapse formation // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from direct assay /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0002369 // T cell cytokine production // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // non-traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031579 // membrane raft organization // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042982 // amyloid precursor protein metabolic process // inferred from electronic annotation /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048745 // smooth muscle tissue development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060022 // hard palate development // inferred from electronic annotation /// 0070830 // tight junction assembly // inferred from direct assay /// 0072659 // protein localization to plasma membrane // inferred from mutant phenotype /// 0072659 // protein localization to plasma membrane // traceable author statement /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 1902305 // regulation of sodium ion transmembrane transport // traceable author statement 0001772 // immunological synapse // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0014704 // intercalated disc // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from electronic annotation /// 0035748 // myelin sheath abaxonal region // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043219 // lateral loop // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097025 // MPP7-DLG1-LIN7 complex // inferred from direct assay 0004385 // guanylate kinase activity // traceable author statement /// 0004721 // phosphoprotein phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0015459 // potassium channel regulator activity // non-traceable author statement /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0097016 // L27 domain binding // inferred from physical interaction 202517_at NM_001313 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001313.1 /DEF=Homo sapiens collapsin response mediator protein 1 (CRMP1), mRNA. /FEA=mRNA /GEN=CRMP1 /PROD=collapsin response mediator protein 1 /DB_XREF=gi:4503050 /UG=Hs.155392 collapsin response mediator protein 1 /FL=gb:BC000252.1 gb:D78012.1 gb:NM_001313.1 gb:U17278.1" NM_001313 collapsin response mediator protein 1 CRMP1 1400 NM_001014809 /// NM_001288661 /// NM_001288662 /// NM_001313 /// XM_005247940 /// XM_005247941 /// XM_005247942 /// XM_005247943 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation" 202518_at NM_001707 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001707.1 /DEF=Homo sapiens B-cell CLLlymphoma 7B (BCL7B), mRNA. /FEA=mRNA /GEN=BCL7B /PROD=B-cell CLLlymphoma 7B /DB_XREF=gi:4502384 /UG=Hs.16269 B-cell CLLlymphoma 7B /FL=gb:BC000956.2 gb:BC001967.1 gb:NM_001707.1" NM_001707 B-cell CLL/lymphoma 7B BCL7B 9275 NM_001197244 /// NM_001707 /// NM_138707 /// NR_036682 /// XM_006716177 0003779 // actin binding // non-traceable author statement 202519_at NM_014938 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014938.1 /DEF=Homo sapiens KIAA0867 protein (MONDOA), mRNA. /FEA=mRNA /GEN=MONDOA /PROD=MondoA protein /DB_XREF=gi:7662347 /UG=Hs.52081 KIAA0867 protein /FL=gb:AB020674.1 gb:NM_014938.1" NM_014938 MLX interacting protein MLXIP 22877 NM_014938 /// XM_006719290 /// XM_006719291 /// XM_006719292 /// XM_006719293 /// XM_006719294 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 202520_s_at NM_000249 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000249.1 /DEF=Homo sapiens mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2) (MLH1), mRNA. /FEA=mRNA /GEN=MLH1 /PROD=mutL homolog 1 /DB_XREF=gi:4557756 /UG=Hs.57301 mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2) /FL=gb:NM_000249.1 gb:U07343.1 gb:U07418.1" NM_000249 mutL homolog 1 MLH1 4292 NM_000249 /// NM_001167617 /// NM_001167618 /// NM_001167619 /// NM_001258271 /// NM_001258273 /// NM_001258274 /// XM_005265161 /// XM_005265163 /// XM_005265164 /// XM_005265166 /// XR_427268 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // inferred from electronic annotation /// 0000712 // resolution of meiotic recombination intermediates // inferred from electronic annotation /// 0002204 // somatic recombination of immunoglobulin genes involved in immune response // inferred from electronic annotation /// 0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007060 // male meiosis chromosome segregation // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007129 // synapsis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // /// 0007140 // male meiosis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0043060 // meiotic metaphase I plate congression // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0045950 // negative regulation of mitotic recombination // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0051257 // spindle midzone assembly involved in meiosis // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // not recorded /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005712 // chiasma // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032300 // mismatch repair complex // inferred from electronic annotation /// 0032300 // mismatch repair complex // /// 0032389 // MutLalpha complex // not recorded /// 0032390 // MutLbeta complex // 0003697 // single-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // not recorded /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0032137 // guanine/thymine mispair binding // inferred from electronic annotation /// 0032407 // MutSalpha complex binding // inferred from direct assay /// 0043566 // structure-specific DNA binding // inferred from electronic annotation 202521_at NM_006565 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006565.1 /DEF=Homo sapiens CCCTC-binding factor (zinc finger protein) (CTCF), mRNA. /FEA=mRNA /GEN=CTCF /PROD=CCCTC-binding factor (zinc finger protein) /DB_XREF=gi:5729789 /UG=Hs.57419 CCCTC-binding factor (zinc finger protein) /FL=gb:NM_006565.1 gb:U25435.1" NM_006565 CCCTC-binding factor (zinc finger protein) CTCF 10664 NM_001191022 /// NM_006565 /// XM_005255775 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0010216 // maintenance of DNA methylation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016584 // nucleosome positioning // inferred from direct assay /// 0031060 // regulation of histone methylation // inferred from electronic annotation /// 0035065 // regulation of histone acetylation // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from mutant phenotype /// 0040030 // regulation of molecular function, epigenetic // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0070602 // regulation of centromeric sister chromatid cohesion // non-traceable author statement" "0000775 // chromosome, centromeric region // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay" 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0043035 // chromatin insulator sequence binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202522_at AL031591 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL031591 /DEF=Human DNA sequence from clone RP3-353E16 on chromosome 22q11.22-12.3 Contains the 5 part of the MN1 gene for meningioma (disrupted in balanced translocation) 1, the PITPNB gene for phosphatidylinositol transfer protein beta, ESTs, STSs, GSSs and ... /FEA=mRNA /DB_XREF=gi:6006484 /UG=Hs.7370 phosphotidylinositol transfer protein, beta /FL=gb:D30037.1 gb:NM_012399.1" AL031591 "phosphatidylinositol transfer protein, beta" PITPNB 23760 NM_001284277 /// NM_001284278 /// NM_012399 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015914 // phospholipid transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008289 // lipid binding // inferred from electronic annotation 202523_s_at AI952009 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI952009 /FEA=EST /DB_XREF=gi:5744319 /DB_XREF=est:wx40f07.x1 /CLONE=IMAGE:2546149 /UG=Hs.74583 KIAA0275 gene product /FL=gb:D87465.1 gb:NM_014767.1 AI952009 "sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2" SPOCK2 9806 NM_001134434 /// NM_001244950 /// NM_014767 /// XM_005270302 0007165 // signal transduction // inferred from electronic annotation /// 0007416 // synapse assembly // non-traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202524_s_at NM_014767 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014767.1 /DEF=Homo sapiens KIAA0275 gene product (KIAA0275), mRNA. /FEA=mRNA /GEN=KIAA0275 /PROD=KIAA0275 gene product /DB_XREF=gi:7662035 /UG=Hs.74583 KIAA0275 gene product /FL=gb:D87465.1 gb:NM_014767.1" NM_014767 "sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2" SPOCK2 9806 NM_001134434 /// NM_001244950 /// NM_014767 /// XM_005270302 0007165 // signal transduction // inferred from electronic annotation /// 0007416 // synapse assembly // non-traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 202525_at NM_002773 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002773.1 /DEF=Homo sapiens protease, serine, 8 (prostasin) (PRSS8), mRNA. /FEA=mRNA /GEN=PRSS8 /PROD=protease, serine, 8 (prostasin) /DB_XREF=gi:4506152 /UG=Hs.75799 protease, serine, 8 (prostasin) /FL=gb:BC001462.1 gb:NM_002773.1 gb:L41351.1" NM_002773 "protease, serine, 8" PRSS8 5652 NM_002773 0006508 // proteolysis // inferred from electronic annotation /// 0010765 // positive regulation of sodium ion transport // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 202526_at U44378 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:U44378.1 /DEF=Human homozygous deletion target in pancreatic carcinoma (DPC4) mRNA, complete cds. /FEA=mRNA /GEN=DPC4 /PROD=Dpc4 /DB_XREF=gi:1163233 /UG=Hs.75862 MAD (mothers against decapentaplegic, Drosophila) homolog 4 /FL=gb:U44378.1 gb:BC002379.1 gb:NM_005359.1" U44378 SMAD family member 4 SMAD4 4089 NM_005359 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0003190 // atrioventricular valve formation // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0003251 // positive regulation of cell proliferation involved in heart valve morphogenesis // inferred from electronic annotation /// 0003279 // cardiac septum development // inferred from electronic annotation /// 0003360 // brainstem development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from sequence or structural similarity /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036302 // atrioventricular canal development // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0048859 // formation of anatomical boundary // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051797 // regulation of hair follicle development // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0060956 // endocardial cell differentiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0071141 // SMAD protein complex // inferred from direct assay "0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0030616 // transforming growth factor beta receptor, common-partner cytoplasmic mediator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction" 202527_s_at NM_005359 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005359.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 4 (MADH4), mRNA. /FEA=mRNA /GEN=MADH4 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 4 /DB_XREF=gi:4885456 /UG=Hs.75862 MAD (mothers against decapentaplegic, Drosophila) homolog 4 /FL=gb:U44378.1 gb:BC002379.1 gb:NM_005359.1" NM_005359 SMAD family member 4 SMAD4 4089 NM_005359 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0003190 // atrioventricular valve formation // inferred from electronic annotation /// 0003198 // epithelial to mesenchymal transition involved in endocardial cushion formation // inferred from electronic annotation /// 0003251 // positive regulation of cell proliferation involved in heart valve morphogenesis // inferred from electronic annotation /// 0003279 // cardiac septum development // inferred from electronic annotation /// 0003360 // brainstem development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007369 // gastrulation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from sequence or structural similarity /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // traceable author statement /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0032909 // regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0036302 // atrioventricular canal development // inferred from electronic annotation /// 0042118 // endothelial cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0048859 // formation of anatomical boundary // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from electronic annotation /// 0051797 // regulation of hair follicle development // inferred from electronic annotation /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0060956 // endocardial cell differentiation // inferred from electronic annotation /// 0071559 // response to transforming growth factor beta // inferred from direct assay /// 0072133 // metanephric mesenchyme morphogenesis // inferred from electronic annotation /// 0072134 // nephrogenic mesenchyme morphogenesis // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0071141 // SMAD protein complex // inferred from direct assay "0000987 // core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001076 // RNA polymerase II transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0030616 // transforming growth factor beta receptor, common-partner cytoplasmic mediator activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction" 202528_at NM_000403 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000403.2 /DEF=Homo sapiens galactose-4-epimerase, UDP- (GALE), mRNA. /FEA=mRNA /GEN=GALE /PROD=UDP-galactose-4-epimerase /DB_XREF=gi:9945333 /UG=Hs.76057 galactose-4-epimerase, UDP- /FL=gb:BC001273.1 gb:L41668.1 gb:NM_000403.2" NM_000403 UDP-galactose-4-epimerase GALE 2582 NM_000403 /// NM_001008216 /// NM_001127621 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019388 // galactose catabolic process // inferred from direct assay /// 0019388 // galactose catabolic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0003978 // UDP-glucose 4-epimerase activity // not recorded /// 0003978 // UDP-glucose 4-epimerase activity // inferred from direct assay /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016857 // racemase and epimerase activity, acting on carbohydrates and derivatives // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050662 // coenzyme binding // inferred from electronic annotation" 202529_at NM_002766 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002766.1 /DEF=Homo sapiens phosphoribosyl pyrophosphate synthetase-associated protein 1 (PRPSAP1), mRNA. /FEA=mRNA /GEN=PRPSAP1 /PROD=phosphoribosyl pyrophosphatesynthetase-associated protein 1 /DB_XREF=gi:4506130 /UG=Hs.77498 phosphoribosyl pyrophosphate synthetase-associated protein 1 /FL=gb:D61391.1 gb:NM_002766.1" NM_002766 phosphoribosyl pyrophosphate synthetase-associated protein 1 PRPSAP1 5635 NM_002766 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0033673 // negative regulation of kinase activity // inferred from electronic annotation 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0019900 // kinase binding // inferred from electronic annotation /// 0030234 // enzyme regulator activity // inferred from electronic annotation 202530_at NM_001315 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001315.1 /DEF=Homo sapiens mitogen-activated protein kinase 14 (MAPK14), mRNA. /FEA=mRNA /GEN=MAPK14 /PROD=mitogen-activated protein kinase 14 /DB_XREF=gi:4503068 /UG=Hs.79107 mitogen-activated protein kinase 14 /FL=gb:NM_001315.1 gb:L35263.1" NM_001315 mitogen-activated protein kinase 14 MAPK14 1432 NM_001315 /// NM_139012 /// NM_139013 /// NM_139014 /// XM_006714998 "0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010831 // positive regulation of myotube differentiation // inferred from sequence or structural similarity /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038066 // p38MAPK cascade // inferred from sequence or structural similarity /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045663 // positive regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070935 // 3'-UTR-mediated mRNA stabilization // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090400 // stress-induced premature senescence // inferred from mutant phenotype /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype" 0000922 // spindle pole // inferred from electronic annotation /// 0005623 // cell // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0051525 // NFAT protein binding // inferred from sequence or structural similarity" 202531_at NM_002198 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002198.1 /DEF=Homo sapiens interferon regulatory factor 1 (IRF1), mRNA. /FEA=mRNA /GEN=IRF1 /PROD=interferon regulatory factor 1 /DB_XREF=gi:4504720 /UG=Hs.80645 interferon regulatory factor 1 /FL=gb:NM_002198.1" NM_002198 interferon regulatory factor 1 IRF1 3659 NM_002198 /// XR_427711 "0002376 // immune system process // inferred from electronic annotation /// 0002819 // regulation of adaptive immune response // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032481 // positive regulation of type I interferon production // inferred from sequence or structural similarity /// 0032728 // positive regulation of interferon-beta production // inferred from mutant phenotype /// 0034124 // regulation of MyD88-dependent toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0035458 // cellular response to interferon-beta // inferred from direct assay /// 0043374 // CD8-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0045084 // positive regulation of interleukin-12 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0045088 // regulation of innate immune response // traceable author statement /// 0045590 // negative regulation of regulatory T cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 2000564 // regulation of CD8-positive, alpha-beta T cell proliferation // inferred from sequence or structural similarity" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202532_s_at BC000192 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000192.1 /DEF=Homo sapiens, dihydrofolate reductase, clone MGC:857, mRNA, complete cds. /FEA=mRNA /PROD=dihydrofolate reductase /DB_XREF=gi:12652874 /UG=Hs.83765 dihydrofolate reductase /FL=gb:BC000192.1 gb:BC003584.1 gb:NM_000791.2" BC000192 dihydrofolate reductase DHFR 1719 NM_000791 /// NM_001290354 /// NM_001290357 /// NR_110936 /// XM_005248455 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // non-traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // non-traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from electronic annotation /// 0004146 // dihydrofolate reductase activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 202533_s_at BC003584 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003584.1 /DEF=Homo sapiens, dihydrofolate reductase, clone MGC:3153, mRNA, complete cds. /FEA=mRNA /PROD=dihydrofolate reductase /DB_XREF=gi:13097773 /UG=Hs.83765 dihydrofolate reductase /FL=gb:BC000192.1 gb:BC003584.1 gb:NM_000791.2" BC003584 dihydrofolate reductase DHFR 1719 NM_000791 /// NM_001290354 /// NM_001290357 /// NR_110936 /// XM_005248455 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // non-traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // non-traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from electronic annotation /// 0004146 // dihydrofolate reductase activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 202534_x_at NM_000791 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000791.2 /DEF=Homo sapiens dihydrofolate reductase (DHFR), mRNA. /FEA=mRNA /GEN=DHFR /PROD=dihydrofolate reductase /DB_XREF=gi:7262376 /UG=Hs.83765 dihydrofolate reductase /FL=gb:BC000192.1 gb:BC003584.1 gb:NM_000791.2" NM_000791 dihydrofolate reductase DHFR 1719 NM_000791 /// NM_001290354 /// NM_001290357 /// NR_110936 /// XM_005248455 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006545 // glycine biosynthetic process // inferred from electronic annotation /// 0006545 // glycine biosynthetic process // non-traceable author statement /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // non-traceable author statement /// 0031427 // response to methotrexate // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0046655 // folic acid metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from direct assay /// 0004146 // dihydrofolate reductase activity // inferred from electronic annotation /// 0004146 // dihydrofolate reductase activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 202535_at NM_003824 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003824.1 /DEF=Homo sapiens Fas (TNFRSF6)-associated via death domain (FADD), mRNA. /FEA=mRNA /GEN=FADD /PROD=Fas (TNFRSF6)-associated via death domain /DB_XREF=gi:4505228 /UG=Hs.86131 Fas (TNFRSF6)-associated via death domain /FL=gb:BC000334.1 gb:NM_003824.1 gb:U24231.1" NM_003824 Fas (TNFRSF6)-associated via death domain FADD 8772 NM_003824 "0001916 // positive regulation of T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0002821 // positive regulation of adaptive immune response // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from direct assay /// 0033077 // T cell differentiation in thymus // inferred from sequence or structural similarity /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0036462 // TRAIL-activated apoptotic signaling pathway // inferred from direct assay /// 0042104 // positive regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0045087 // innate immune response // traceable author statement /// 0045651 // positive regulation of macrophage differentiation // inferred from mutant phenotype /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048535 // lymph node development // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0070236 // negative regulation of activation-induced cell death of T cells // inferred from sequence or structural similarity /// 0070265 // necrotic cell death // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0097049 // motor neuron apoptotic process // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 0097527 // necroptotic signaling pathway // inferred from mutant phenotype /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000454 // positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement" 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0031264 // death-inducing signaling complex // traceable author statement /// 0031265 // CD95 death-inducing signaling complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0097342 // ripoptosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from physical interaction /// 0005123 // death receptor binding // traceable author statement /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from physical interaction /// 0035877 // death effector domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202536_at AK002165 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK002165.1 /DEF=Homo sapiens cDNA FLJ11303 fis, clone PLACE1009995, highly similar to Homo sapiens mRNA; cDNA DKFZp564O123. /FEA=mRNA /DB_XREF=gi:7023876 /UG=Hs.11449 DKFZP564O123 protein /FL=gb:AF151842.1 gb:AL080122.1 gb:NM_014043.1" AK002165 charged multivesicular body protein 2B CHMP2B 25978 NM_001244644 /// NM_014043 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202537_s_at AF151842 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF151842.1 /DEF=Homo sapiens CGI-84 protein mRNA, complete cds. /FEA=mRNA /PROD=CGI-84 protein /DB_XREF=gi:4929636 /UG=Hs.11449 DKFZP564O123 protein /FL=gb:AF151842.1 gb:AL080122.1 gb:NM_014043.1" AF151842 charged multivesicular body protein 2B CHMP2B 25978 NM_001244644 /// NM_014043 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202538_s_at NM_014043 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014043.1 /DEF=Homo sapiens DKFZP564O123 protein (DKFZP564O123), mRNA. /FEA=mRNA /GEN=DKFZP564O123 /PROD=DKFZP564O123 protein /DB_XREF=gi:7661633 /UG=Hs.11449 DKFZP564O123 protein /FL=gb:AF151842.1 gb:AL080122.1 gb:NM_014043.1" NM_014043 charged multivesicular body protein 2B CHMP2B 25978 NM_001244644 /// NM_014043 0006810 // transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016197 // endosomal transport // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 202539_s_at AL518627 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL518627 /FEA=EST /DB_XREF=gi:12782120 /DB_XREF=est:AL518627 /CLONE=CS0DA009YG15 (3 prime) /UG=Hs.11899 3-hydroxy-3-methylglutaryl-Coenzyme A reductase /FL=gb:M11058.1 gb:NM_000859.1 AL518627 3-hydroxy-3-methylglutaryl-CoA reductase HMGCR 3156 NM_000859 /// NM_001130996 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006743 // ubiquinone metabolic process // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from electronic annotation /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0015936 // coenzyme A metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045908 // negative regulation of vasodilation // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004420 // hydroxymethylglutaryl-CoA reductase (NADPH) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042282 // hydroxymethylglutaryl-CoA reductase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from direct assay /// 0070402 // NADPH binding // inferred from direct assay" 202540_s_at NM_000859 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000859.1 /DEF=Homo sapiens 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (HMGCR), mRNA. /FEA=mRNA /GEN=HMGCR /PROD=3-hydroxy-3-methylglutaryl-Coenzyme A reductase /DB_XREF=gi:4557642 /UG=Hs.11899 3-hydroxy-3-methylglutaryl-Coenzyme A reductase /FL=gb:M11058.1 gb:NM_000859.1" NM_000859 3-hydroxy-3-methylglutaryl-CoA reductase HMGCR 3156 NM_000859 /// NM_001130996 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006743 // ubiquinone metabolic process // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010664 // negative regulation of striated muscle cell apoptotic process // inferred from electronic annotation /// 0010666 // positive regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0015936 // coenzyme A metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045908 // negative regulation of vasodilation // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061045 // negative regulation of wound healing // inferred from electronic annotation /// 0061179 // negative regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation 0005778 // peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004420 // hydroxymethylglutaryl-CoA reductase (NADPH) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042282 // hydroxymethylglutaryl-CoA reductase activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from direct assay /// 0070402 // NADPH binding // inferred from direct assay" 202541_at BF589679 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF589679 /FEA=EST /DB_XREF=gi:11682003 /DB_XREF=est:naa08b05.x1 /CLONE=IMAGE:3253977 /UG=Hs.146401 small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) /FL=gb:NM_004757.1 gb:U10117.1" BF589679 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 AIMP1 9255 NM_001142415 /// NM_001142416 /// NM_004757 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009611 // response to wounding // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 202542_s_at NM_004757 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004757.1 /DEF=Homo sapiens small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) (SCYE1), mRNA. /FEA=mRNA /GEN=SCYE1 /PROD=small inducible cytokine subfamily E, member 1 /DB_XREF=gi:4758265 /UG=Hs.146401 small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) /FL=gb:NM_004757.1 gb:U10117.1" NM_004757 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 AIMP1 9255 NM_001142415 /// NM_001142416 /// NM_004757 0001525 // angiogenesis // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0009611 // response to wounding // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 202543_s_at BC005359 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005359.1 /DEF=Homo sapiens, glia maturation factor, beta, clone MGC:12462, mRNA, complete cds. /FEA=mRNA /PROD=glia maturation factor, beta /DB_XREF=gi:13529184 /UG=Hs.151413 glia maturation factor, beta /FL=gb:BC005359.1 gb:M86492.1 gb:AB001106.1 gb:NM_004124.1" BC005359 "glia maturation factor, beta" GMFB 2764 NM_004124 /// XM_005267541 /// XM_006720118 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005622 // intracellular // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0008047 // enzyme activator activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 202544_at NM_004124 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004124.1 /DEF=Homo sapiens glia maturation factor, beta (GMFB), mRNA. /FEA=mRNA /GEN=GMFB /PROD=glia maturation factor, beta /DB_XREF=gi:4758441 /UG=Hs.151413 glia maturation factor, beta /FL=gb:BC005359.1 gb:M86492.1 gb:AB001106.1 gb:NM_004124.1" NM_004124 "glia maturation factor, beta" GMFB 2764 NM_004124 /// XM_005267541 /// XM_006720118 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005622 // intracellular // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0008047 // enzyme activator activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 202545_at NM_006254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006254.1 /DEF=Homo sapiens protein kinase C, delta (PRKCD), mRNA. /FEA=mRNA /GEN=PRKCD /PROD=protein kinase C, delta /DB_XREF=gi:5453969 /UG=Hs.155342 protein kinase C, delta /FL=gb:L07860.1 gb:L07861.1 gb:D10495.1 gb:NM_006254.1" NM_006254 "protein kinase C, delta" PRKCD 5580 NM_006254 /// NM_212539 /// XM_006713257 /// XM_006713258 /// XM_006713259 0001666 // response to hypoxia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010469 // regulation of receptor activity // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0023021 // termination of signal transduction // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030837 // negative regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0032091 // negative regulation of protein binding // traceable author statement /// 0032613 // interleukin-10 production // inferred from electronic annotation /// 0032615 // interleukin-12 production // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032930 // positive regulation of superoxide anion generation // inferred from mutant phenotype /// 0032963 // collagen metabolic process // inferred from electronic annotation /// 0034351 // negative regulation of glial cell apoptotic process // inferred from mutant phenotype /// 0035307 // positive regulation of protein dephosphorylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042100 // B cell proliferation // inferred from electronic annotation /// 0042119 // neutrophil activation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046326 // positive regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050821 // protein stabilization // non-traceable author statement /// 0051490 // negative regulation of filopodium assembly // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0090331 // negative regulation of platelet aggregation // inferred from sequence or structural similarity /// 0090398 // cellular senescence // inferred from mutant phenotype /// 1900163 // positive regulation of phospholipid scramblase activity // inferred from mutant phenotype /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from mutant phenotype /// 2000753 // positive regulation of glucosylceramide catabolic process // inferred from mutant phenotype /// 2000755 // positive regulation of sphingomyelin catabolic process // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from mutant phenotype /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004697 // protein kinase C activity // inferred from sequence or structural similarity /// 0004699 // calcium-independent protein kinase C activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070976 // TIR domain binding // inferred from electronic annotation" 202546_at NM_003761 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003761.1 /DEF=Homo sapiens vesicle-associated membrane protein 8 (endobrevin) (VAMP8), mRNA. /FEA=mRNA /GEN=VAMP8 /PROD=vesicle-associated membrane protein 8 /DB_XREF=gi:4507864 /UG=Hs.172684 vesicle-associated membrane protein 8 (endobrevin) /FL=gb:BC001634.1 gb:AF053233.1 gb:NM_003761.1" NM_003761 vesicle-associated membrane protein 8 VAMP8 8673 NM_003761 0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // not recorded /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // not recorded /// 0006906 // vesicle fusion // not recorded /// 0006914 // autophagy // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0046718 // viral entry into host cell // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0061025 // membrane fusion // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030667 // secretory granule membrane // traceable author statement /// 0031201 // SNARE complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation 202547_s_at AA778936 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA778936 /FEA=EST /DB_XREF=gi:2838267 /DB_XREF=est:zj38h05.s1 /CLONE=IMAGE:452601 /UG=Hs.172813 PAK-interacting exchange factor beta /FL=gb:D63476.1 gb:NM_003899.1 AA778936 Rho guanine nucleotide exchange factor (GEF) 7 ARHGEF7 8874 NM_001113511 /// NM_001113512 /// NM_001113513 /// NM_003899 /// NM_145735 /// XM_005254085 /// XM_005254086 /// XM_005254087 /// XM_005254088 /// XM_005254089 /// XM_005254090 /// XM_005254091 /// XM_005254092 /// XM_005254093 /// XM_005254094 /// XM_005254095 /// XM_006719956 /// XM_006719957 /// XM_006719958 /// XM_006719959 /// XM_006719960 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 202548_s_at NM_003899 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003899.1 /DEF=Homo sapiens PAK-interacting exchange factor beta (P85SPR), mRNA. /FEA=mRNA /GEN=P85SPR /PROD=PAK-interacting exchange factor beta /DB_XREF=gi:4505572 /UG=Hs.172813 PAK-interacting exchange factor beta /FL=gb:D63476.1 gb:NM_003899.1" NM_003899 Rho guanine nucleotide exchange factor (GEF) 7 ARHGEF7 8874 NM_001113511 /// NM_001113512 /// NM_001113513 /// NM_003899 /// NM_145735 /// XM_005254085 /// XM_005254086 /// XM_005254087 /// XM_005254088 /// XM_005254089 /// XM_005254090 /// XM_005254091 /// XM_005254092 /// XM_005254093 /// XM_005254094 /// XM_005254095 /// XM_006719956 /// XM_006719957 /// XM_006719958 /// XM_006719959 /// XM_006719960 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 202549_at AK025720 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK025720.1 /DEF=Homo sapiens cDNA: FLJ22067 fis, clone HEP11115F, highly similar to AF086629 Homo sapiens VAMP-associated protein C (VAP-C) mRNA. /FEA=mRNA /DB_XREF=gi:10438329 /UG=Hs.182625 VAMP (vesicle-associated membrane protein)-associated protein B and C /FL=gb:BC001712.1 gb:AF086628.1 gb:NM_004738.1 gb:AF160212.1" AK025720 VAMP (vesicle-associated membrane protein)-associated protein B and C VAPB 9217 NM_001195677 /// NM_004738 /// NR_036633 /// XM_006723888 0006665 // sphingolipid metabolic process // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay 202550_s_at NM_004738 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004738.1 /DEF=Homo sapiens VAMP (vesicle-associated membrane protein)-associated protein B and C (VAPB), mRNA. /FEA=mRNA /GEN=VAPB /PROD=VAMP (vesicle-associated membraneprotein)-associated protein B and C /DB_XREF=gi:4759301 /UG=Hs.182625 VAMP (vesicle-associated membrane protein)-associated protein B and C /FL=gb:BC001712.1 gb:AF086628.1 gb:NM_004738.1 gb:AF160212.1" NM_004738 VAMP (vesicle-associated membrane protein)-associated protein B and C VAPB 9217 NM_001195677 /// NM_004738 /// NR_036633 /// XM_006723888 0006665 // sphingolipid metabolic process // traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from mutant phenotype /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from direct assay /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from direct assay 202551_s_at BG546884 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG546884 /FEA=EST /DB_XREF=gi:13545549 /DB_XREF=est:602574066F1 /CLONE=IMAGE:4702049 /UG=Hs.19280 cysteine-rich motor neuron 1 /FL=gb:NM_016441.1 gb:AF167706.1 BG546884 cysteine rich transmembrane BMP regulator 1 (chordin-like) /// uncharacterized LOC101929500 CRIM1 /// LOC101929500 51232 /// 101929500 NM_016441 /// XM_005264357 /// XM_005264358 /// XR_244983 /// XR_249109 /// XR_251054 /// XR_426983 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay 202552_s_at NM_016441 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016441.1 /DEF=Homo sapiens cysteine-rich motor neuron 1 (CRIM1), mRNA. /FEA=mRNA /GEN=CRIM1 /PROD=cysteine-rich motor neuron 1 /DB_XREF=gi:10092638 /UG=Hs.19280 cysteine-rich motor neuron 1 /FL=gb:NM_016441.1 gb:AF167706.1" NM_016441 cysteine rich transmembrane BMP regulator 1 (chordin-like) /// uncharacterized LOC101929500 CRIM1 /// LOC101929500 51232 /// 101929500 NM_016441 /// XM_005264357 /// XM_005264358 /// XR_244983 /// XR_249109 /// XR_251054 /// XR_426983 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0048009 // insulin-like growth factor receptor signaling pathway // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay 202553_s_at NM_015484 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015484.1 /DEF=Homo sapiens GCIP-interacting protein p29 (P29), mRNA. /FEA=mRNA /GEN=P29 /PROD=GCIP-interacting protein p29 /DB_XREF=gi:7661635 /UG=Hs.20013 GCIP-interacting protein p29 /FL=gb:AF273089.1 gb:AL080166.1 gb:NM_015484.1" NM_015484 SYF2 pre-mRNA-splicing factor SYF2 25949 NM_015484 /// NM_207170 "0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 202554_s_at AL527430 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL527430 /FEA=EST /DB_XREF=gi:12790923 /DB_XREF=est:AL527430 /CLONE=CS0DC021YF13 (5 prime) /UG=Hs.2006 glutathione S-transferase M3 (brain) /FL=gb:BC000088.1 gb:J05459.1 gb:NM_000849.1 AL527430 glutathione S-transferase mu 3 (brain) GSTM3 2947 NM_000849 /// NR_024537 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008065 // establishment of blood-nerve barrier // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018916 // nitrobenzene metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0070458 // cellular detoxification of nitrogen compound // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 202555_s_at NM_005965 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005965.1 /DEF=Homo sapiens myosin, light polypeptide kinase (MYLK), mRNA. /FEA=mRNA /GEN=MYLK /PROD=myosin, light polypeptide kinase /DB_XREF=gi:5174600 /UG=Hs.211582 myosin, light polypeptide kinase /FL=gb:AB037663.1 gb:NM_005965.1 gb:AF069601.2" NM_005965 myosin light chain kinase MYLK 4638 NM_005965 /// NM_053025 /// NM_053026 /// NM_053027 /// NM_053028 /// NM_053029 /// NM_053030 /// NM_053031 /// NM_053032 /// XM_005247492 /// XM_005247493 /// XM_005247494 /// XM_006713649 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0006939 // smooth muscle contraction // not recorded /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0007015 // actin filament organization // not recorded /// 0014820 // tonic smooth muscle contraction // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032060 // bleb assembly // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0060414 // aorta smooth muscle tissue morphogenesis // inferred from mutant phenotype /// 0071476 // cellular hypotonic response // inferred from direct assay /// 0090303 // positive regulation of wound healing // inferred from direct assay 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004687 // myosin light chain kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 202556_s_at NM_006337 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006337.1 /DEF=Homo sapiens microspherule protein 1 (MCRS1), mRNA. /FEA=mRNA /GEN=MCRS1 /PROD=microspherule protein 1 /DB_XREF=gi:5453693 /UG=Hs.25313 microspherule protein 1 /FL=gb:AF068007.1 gb:NM_006337.1" NM_006337 microspherule protein 1 MCRS1 10445 NM_001012300 /// NM_001278341 /// NM_006337 /// XM_005268572 /// XM_005268573 "0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043981 // histone H4-K5 acetylation // inferred from direct assay /// 0043982 // histone H4-K8 acetylation // inferred from direct assay /// 0043984 // histone H4-K16 acetylation // inferred from direct assay" 0000123 // histone acetyltransferase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0031011 // Ino80 complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0043995 // histone acetyltransferase activity (H4-K5 specific) // inferred from direct assay /// 0043996 // histone acetyltransferase activity (H4-K8 specific) // inferred from direct assay /// 0046972 // histone acetyltransferase activity (H4-K16 specific) // inferred from direct assay 202557_at AI718418 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI718418 /FEA=EST /DB_XREF=gi:5035674 /DB_XREF=est:as43b01.x1 /CLONE=IMAGE:2319913 /UG=Hs.288799 stress 70 protein chaperone, microsome-associated, 60kD /FL=gb:U04735.1 gb:NM_006948.1" AI718418 "heat shock protein 70kDa family, member 13" HSPA13 6782 NM_006948 0000902 // cell morphogenesis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 202558_s_at NM_006948 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006948.1 /DEF=Homo sapiens stress 70 protein chaperone, microsome-associated, 60kD (STCH), mRNA. /FEA=mRNA /GEN=STCH /PROD=stress 70 protein chaperone,microsome-associated, 60kD /DB_XREF=gi:5902125 /UG=Hs.288799 stress 70 protein chaperone, microsome-associated, 60kD /FL=gb:U04735.1 gb:NM_006948.1" NM_006948 "heat shock protein 70kDa family, member 13" HSPA13 6782 NM_006948 0000902 // cell morphogenesis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 202559_x_at AW005776 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW005776 /FEA=EST /DB_XREF=gi:5854554 /DB_XREF=est:wz89d09.x1 /CLONE=IMAGE:2566001 /UG=Hs.323817 DKFZP547E1010 protein /FL=gb:NM_015607.1 AW005776 chromatin target of PRMT1 CHTOP 26097 NM_001206612 /// NM_001244664 /// NM_015607 /// XM_005245085 /// XM_005245086 /// XM_006711269 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay" 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202560_s_at NM_015607 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015607.1 /DEF=Homo sapiens DKFZP547E1010 protein (DKFZP547E1010), mRNA. /FEA=mRNA /GEN=DKFZP547E1010 /PROD=DKFZP547E1010 protein /DB_XREF=gi:7661589 /UG=Hs.323817 DKFZP547E1010 protein /FL=gb:NM_015607.1" NM_015607 chromatin target of PRMT1 CHTOP 26097 NM_001206612 /// NM_001244664 /// NM_015607 /// XM_005245085 /// XM_005245086 /// XM_006711269 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0032781 // positive regulation of ATPase activity // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay" 0000346 // transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202561_at AF070613 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF070613.1 /DEF=Homo sapiens clone 24585 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3387995 /UG=Hs.131814 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase /FL=gb:AF082556.1 gb:NM_003747.1" AF070613 "tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase" TNKS 8658 NM_003747 /// XM_006716263 "0000209 // protein polyubiquitination // inferred from direct assay /// 0006471 // protein ADP-ribosylation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0032210 // regulation of telomere maintenance via telomerase // inferred by curator /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from direct assay /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051225 // spindle assembly // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype /// 0070212 // protein poly-ADP-ribosylation // inferred from direct assay /// 0070213 // protein auto-ADP-ribosylation // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype" "0000139 // Golgi membrane // inferred from electronic annotation /// 0000242 // pericentriolar material // traceable author statement /// 0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031965 // nuclear membrane // traceable author statement" "0003950 // NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 202562_s_at AL136658 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:AL136658.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564H0664 (from clone DKFZp564H0664); complete cds. /FEA=mRNA /GEN=DKFZp564H0664 /PROD=hypothetical protein /DB_XREF=gi:12052839 /UG=Hs.15106 chromosome 14 open reading frame 1 /FL=gb:AL136658.1 gb:AF136971.1 gb:BC002444.1 gb:AF134159.2 gb:NM_007176.1 AL136658 chromosome 14 open reading frame 1 C14orf1 11161 NM_007176 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030133 // transport vesicle // inferred from direct assay 202563_at NM_007176 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007176.1 /DEF=Homo sapiens chromosome 14 open reading frame 1 (C14ORF1), mRNA. /FEA=mRNA /GEN=C14ORF1 /PROD=chromosome 14 open reading frame 1 /DB_XREF=gi:6005718 /UG=Hs.15106 chromosome 14 open reading frame 1 /FL=gb:AL136658.1 gb:AF136971.1 gb:BC002444.1 gb:AF134159.2 gb:NM_007176.1" NM_007176 chromosome 14 open reading frame 1 C14orf1 11161 NM_007176 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030133 // transport vesicle // inferred from direct assay 202564_x_at NM_001667 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001667.1 /DEF=Homo sapiens ADP-ribosylation factor-like 2 (ARL2), mRNA. /FEA=mRNA /GEN=ARL2 /PROD=ADP-ribosylation factor-like 2 /DB_XREF=gi:4502228 /UG=Hs.154162 ADP-ribosylation factor-like 2 /FL=gb:BC002530.1 gb:L13687.1 gb:NM_001667.1" NM_001667 ADP-ribosylation factor-like 2 ARL2 402 NM_001199745 /// NM_001667 0006184 // GTP catabolic process // inferred from mutant phenotype /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007021 // tubulin complex assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0031113 // regulation of microtubule polymerization // inferred from mutant phenotype /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0051297 // centrosome organization // inferred from mutant phenotype /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0070830 // tight junction assembly // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from mutant phenotype /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from mutant phenotype /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation 202565_s_at NM_003174 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003174.2 /DEF=Homo sapiens supervillin (SVIL), transcript variant 1, mRNA. /FEA=mRNA /GEN=SVIL /PROD=supervillin, isoform 1 /DB_XREF=gi:11496980 /UG=Hs.154567 supervillin /FL=gb:NM_003174.2 gb:AF051850.1 gb:AF051851.1" NM_003174 supervillin SVIL 6840 NM_003174 /// NM_021738 /// XM_005252564 /// XM_005252565 /// XM_005252566 /// XM_005252567 /// XM_005252568 /// XM_005252569 /// XM_005252570 /// XM_005252571 /// XM_005252572 /// XM_005252573 /// XM_006717492 /// XM_006717493 /// XM_006717494 /// XM_006717495 /// XM_006717496 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0071437 // invadopodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 202566_s_at AF051851 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF051851.1 /DEF=Homo sapiens supervillin mRNA, complete cds. /FEA=mRNA /PROD=supervillin /DB_XREF=gi:2961251 /UG=Hs.154567 supervillin /FL=gb:NM_003174.2 gb:AF051850.1 gb:AF051851.1" AF051851 supervillin SVIL 6840 NM_003174 /// NM_021738 /// XM_005252564 /// XM_005252565 /// XM_005252566 /// XM_005252567 /// XM_005252568 /// XM_005252569 /// XM_005252570 /// XM_005252571 /// XM_005252572 /// XM_005252573 /// XM_006717492 /// XM_006717493 /// XM_006717494 /// XM_006717495 /// XM_006717496 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype 0002102 // podosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0071437 // invadopodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051015 // actin filament binding // inferred from direct assay 202567_at NM_004175 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004175.1 /DEF=Homo sapiens small nuclear ribonucleoprotein D3 polypeptide (18kD) (SNRPD3), mRNA. /FEA=mRNA /GEN=SNRPD3 /PROD=small nuclear ribonucleoprotein D3 polypeptide(18kD) /DB_XREF=gi:4759159 /UG=Hs.1575 small nuclear ribonucleoprotein D3 polypeptide (18kD) /FL=gb:BC000457.1 gb:BC003150.1 gb:NM_004175.1 gb:U15009.1" NM_004175 small nuclear ribonucleoprotein D3 polypeptide 18kDa SNRPD3 6634 NM_001278656 /// NM_004175 /// NR_103819 "0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071208 // histone pre-mRNA DCP binding // inferred from sequence or structural similarity 202568_s_at AI745639 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI745639 /FEA=EST /DB_XREF=gi:5113927 /DB_XREF=est:tr24b01.x1 /CLONE=IMAGE:2219209 /UG=Hs.172766 MAPmicrotubule affinity-regulating kinase 3 /FL=gb:M80359.1 gb:NM_002376.1 AI745639 MAP/microtubule affinity-regulating kinase 3 MARK3 4140 NM_001128918 /// NM_001128919 /// NM_001128920 /// NM_001128921 /// NM_002376 /// XM_005267641 /// XM_005267642 /// XM_005267643 /// XM_006720146 /// XM_006720147 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202569_s_at NM_002376 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002376.1 /DEF=Homo sapiens MAPmicrotubule affinity-regulating kinase 3 (MARK3), mRNA. /FEA=mRNA /GEN=MARK3 /PROD=MAPmicrotubule affinity-regulating kinase 3 /DB_XREF=gi:4505102 /UG=Hs.172766 MAPmicrotubule affinity-regulating kinase 3 /FL=gb:M80359.1 gb:NM_002376.1" NM_002376 MAP/microtubule affinity-regulating kinase 3 MARK3 4140 NM_001128918 /// NM_001128919 /// NM_001128920 /// NM_001128921 /// NM_002376 /// XM_005267641 /// XM_005267642 /// XM_005267643 /// XM_006720146 /// XM_006720147 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202570_s_at BF346592 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF346592 /FEA=EST /DB_XREF=gi:11294104 /DB_XREF=est:602020234F1 /CLONE=IMAGE:4155609 /UG=Hs.177425 KIAA0964 protein /FL=gb:AB023181.1 gb:NM_014902.1 BF346592 "discs, large (Drosophila) homolog-associated protein 4" DLGAP4 22839 NM_001042486 /// NM_014902 /// NM_183006 /// XM_005260329 /// XM_005260331 /// XM_005260332 /// XM_005260333 /// XR_430296 0007267 // cell-cell signaling // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202571_s_at BE550798 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE550798 /FEA=EST /DB_XREF=gi:9792490 /DB_XREF=est:7b59b04.x1 /CLONE=IMAGE:3232495 /UG=Hs.177425 KIAA0964 protein /FL=gb:AB023181.1 gb:NM_014902.1 BE550798 "discs, large (Drosophila) homolog-associated protein 4" DLGAP4 22839 NM_001042486 /// NM_014902 /// NM_183006 /// XM_005260329 /// XM_005260331 /// XM_005260332 /// XM_005260333 /// XR_430296 0007267 // cell-cell signaling // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202572_s_at NM_014902 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014902.1 /DEF=Homo sapiens KIAA0964 protein (KIAA0964), mRNA. /FEA=mRNA /GEN=KIAA0964 /PROD=KIAA0964 protein /DB_XREF=gi:7662411 /UG=Hs.177425 KIAA0964 protein /FL=gb:AB023181.1 gb:NM_014902.1" NM_014902 "discs, large (Drosophila) homolog-associated protein 4" DLGAP4 22839 NM_001042486 /// NM_014902 /// NM_183006 /// XM_005260329 /// XM_005260331 /// XM_005260332 /// XM_005260333 /// XR_430296 0007267 // cell-cell signaling // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202573_at AL530441 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL530441 /FEA=EST /DB_XREF=gi:12793934 /DB_XREF=est:AL530441 /CLONE=CS0DD007YK14 (3 prime) /UG=Hs.181390 casein kinase 1, gamma 2 /FL=gb:NM_001319.2 gb:U89896.1" AL530441 "casein kinase 1, gamma 2" CSNK1G2 1455 NM_001319 /// XM_005259498 /// XM_005259499 /// XM_005259500 /// XM_005259501 /// XM_005259502 /// XR_430129 0006468 // protein phosphorylation // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 202574_s_at NM_001319 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001319.2 /DEF=Homo sapiens casein kinase 1, gamma 2 (CSNK1G2), mRNA. /FEA=mRNA /GEN=CSNK1G2 /PROD=casein kinase 1, gamma 2 /DB_XREF=gi:11079647 /UG=Hs.181390 casein kinase 1, gamma 2 /FL=gb:NM_001319.2 gb:U89896.1" NM_001319 "casein kinase 1, gamma 2" CSNK1G2 1455 NM_001319 /// XM_005259498 /// XM_005259499 /// XM_005259500 /// XM_005259501 /// XM_005259502 /// XR_430129 0006468 // protein phosphorylation // traceable author statement /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 202575_at NM_001878 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001878.2 /DEF=Homo sapiens cellular retinoic acid-binding protein 2 (CRABP2), mRNA. /FEA=mRNA /GEN=CRABP2 /PROD=cellular retinoic acid-binding protein 2 /DB_XREF=gi:6382069 /UG=Hs.183650 cellular retinoic acid-binding protein 2 /FL=gb:BC001109.1 gb:M68867.1 gb:NM_001878.2" NM_001878 cellular retinoic acid binding protein 2 CRABP2 1382 NM_001199723 /// NM_001878 /// XM_006711169 "0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001972 // retinoic acid binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation 202576_s_at AL553254 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL553254 /FEA=EST /DB_XREF=gi:12892919 /DB_XREF=est:AL553254 /CLONE=CS0DI073YF07 (3 prime) /UG=Hs.226396 hypothetical protein FLJ11126 /FL=gb:BC005162.1 gb:NM_018332.1 AL553254 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A /// DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B DDX19A /// DDX19B 11269 /// 55308 NM_001014449 /// NM_001014451 /// NM_001257172 /// NM_001257173 /// NM_001257174 /// NM_001257175 /// NM_007242 /// NM_018332 /// XM_005256030 /// XM_006721126 /// XM_006721127 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202577_s_at BC005162 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005162.1 /DEF=Homo sapiens, hypothetical protein FLJ11126, clone MGC:4651, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ11126 /DB_XREF=gi:13477370 /UG=Hs.226396 hypothetical protein FLJ11126 /FL=gb:BC005162.1 gb:NM_018332.1" BC005162 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A DDX19A 55308 NM_018332 /// XM_005256030 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202578_s_at NM_018332 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018332.1 /DEF=Homo sapiens hypothetical protein FLJ11126 (FLJ11126), mRNA. /FEA=mRNA /GEN=FLJ11126 /PROD=hypothetical protein FLJ11126 /DB_XREF=gi:8922885 /UG=Hs.226396 hypothetical protein FLJ11126 /FL=gb:BC005162.1 gb:NM_018332.1" NM_018332 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A DDX19A 55308 NM_018332 /// XM_005256030 0006810 // transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202579_x_at NM_006353 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006353.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 17-like 3 (HMG17L3), mRNA. /FEA=mRNA /GEN=HMG17L3 /PROD=high-mobility group (nonhistone chromosomal)protein 17-like 3 /DB_XREF=gi:10835239 /UG=Hs.236774 high-mobility group (nonhistone chromosomal) protein 17-like 3 /FL=gb:NM_006353.1 gb:U90549.1" NM_006353 high mobility group nucleosomal binding domain 4 HMGN4 10473 NM_006353 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from electronic annotation 202580_x_at NM_021953 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021953.1 /DEF=Homo sapiens forkhead box M1 (FOXM1), mRNA. /FEA=mRNA /GEN=FOXM1 /PROD=forkhead box M1 /DB_XREF=gi:11386144 /UG=Hs.239 forkhead box M1 /FL=gb:NM_021953.1 gb:U83113.1 gb:L16783.1" NM_021953 forkhead box M1 FOXM1 2305 NM_001243088 /// NM_001243089 /// NM_021953 /// NM_202002 /// NM_202003 /// XM_005253676 "0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // traceable author statement /// 0001570 // vasculogenesis // not recorded /// 0001889 // liver development // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0007049 // cell cycle // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046578 // regulation of Ras protein signal transduction // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded /// 0051726 // regulation of cell cycle // traceable author statement /// 0071156 // regulation of cell cycle arrest // inferred from mutant phenotype /// 0090344 // negative regulation of cell aging // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype /// 2000781 // positive regulation of double-strand break repair // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation" 202581_at NM_005346 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005346.2 /DEF=Homo sapiens heat shock 70kD protein 1B (HSPA1B), mRNA. /FEA=mRNA /GEN=HSPA1B /PROD=heat shock 70kD protein 1B /DB_XREF=gi:5579470 /UG=Hs.274402 heat shock 70kD protein 1B /FL=gb:NM_005346.2" NM_005346 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B HSPA1A /// HSPA1B 3303 /// 3304 NM_005345 /// NM_005346 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0009615 // response to virus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from mutant phenotype /// 0070370 // cellular heat acclimation // inferred from mutant phenotype /// 0090084 // negative regulation of inclusion body assembly // inferred from direct assay /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0001618 // virus receptor activity // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0044183 // protein binding involved in protein folding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement" 202582_s_at AF306510 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF306510.1 /DEF=Homo sapiens RANBPM mRNA, complete cds. /FEA=mRNA /PROD=RANBPM /DB_XREF=gi:13194575 /UG=Hs.279886 RAN binding protein 9 /FL=gb:AF306510.1 gb:AB008515.1 gb:NM_005493.1" AF306510 RAN binding protein 9 RANBP9 10048 NM_005493 /// XM_006714945 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007411 // axon guidance // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 202583_s_at NM_005493 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005493.1 /DEF=Homo sapiens RAN binding protein 9 (RANBP9), mRNA. /FEA=mRNA /GEN=RANBP9 /PROD=RAN binding protein 9 /DB_XREF=gi:4885570 /UG=Hs.279886 RAN binding protein 9 /FL=gb:AF306510.1 gb:AB008515.1 gb:NM_005493.1" NM_005493 RAN binding protein 9 RANBP9 10048 NM_005493 /// XM_006714945 0006461 // protein complex assembly // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007411 // axon guidance // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction 202584_at AW291398 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW291398 /FEA=EST /DB_XREF=gi:6698118 /DB_XREF=est:UI-H-BI2-aga-d-06-0-UI.s1 /CLONE=IMAGE:2723746 /UG=Hs.3187 nuclear transcription factor, X-box binding 1 /FL=gb:NM_002504.1 gb:U15306.1" AW291398 "nuclear transcription factor, X-box binding 1" NFX1 4799 NM_002504 /// NM_147133 /// NM_147134 /// XM_005251473 /// XM_005251474 /// XM_005251475 /// XM_006716776 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202585_s_at NM_002504 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002504.1 /DEF=Homo sapiens nuclear transcription factor, X-box binding 1 (NFX1), mRNA. /FEA=mRNA /GEN=NFX1 /PROD=nuclear transcription factor, X-box binding 1 /DB_XREF=gi:4505386 /UG=Hs.3187 nuclear transcription factor, X-box binding 1 /FL=gb:NM_002504.1 gb:U15306.1" NM_002504 "nuclear transcription factor, X-box binding 1" NFX1 4799 NM_002504 /// NM_147133 /// NM_147134 /// XM_005251473 /// XM_005251474 /// XM_005251475 /// XM_006716776 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045347 // negative regulation of MHC class II biosynthetic process // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202586_at AA772747 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA772747 /FEA=EST /DB_XREF=gi:2824530 /DB_XREF=est:ai54b03.s1 /CLONE=1360781 /UG=Hs.71618 polymerase (RNA) II (DNA directed) polypeptide L (7.6kD) /FL=gb:U37690.1 gb:NM_021128.1 AA772747 "polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa" POLR2L 5441 NM_021128 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" "0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement" 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0008270 // zinc ion binding // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation 202587_s_at BC001116 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001116.1 /DEF=Homo sapiens, adenylate kinase 1, clone MGC:1808, mRNA, complete cds. /FEA=mRNA /PROD=adenylate kinase 1 /DB_XREF=gi:12654562 /UG=Hs.76240 adenylate kinase 1 /FL=gb:BC001116.1 gb:NM_000476.1 gb:AB021871.1" BC001116 adenylate kinase 1 AK1 203 NM_000476 /// XM_005251786 /// XM_005251788 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0001520 // outer dense fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 202588_at NM_000476 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000476.1 /DEF=Homo sapiens adenylate kinase 1 (AK1), mRNA. /FEA=mRNA /GEN=AK1 /PROD=adenylate kinase 1 /DB_XREF=gi:4502010 /UG=Hs.76240 adenylate kinase 1 /FL=gb:BC001116.1 gb:NM_000476.1 gb:AB021871.1" NM_000476 adenylate kinase 1 AK1 203 NM_000476 /// XM_005251786 /// XM_005251788 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046033 // AMP metabolic process // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0001520 // outer dense fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0036126 // sperm flagellum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation 202589_at NM_001071 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001071.1 /DEF=Homo sapiens thymidylate synthetase (TYMS), mRNA. /FEA=mRNA /GEN=TYMS /PROD=thymidylate synthetase /DB_XREF=gi:4507750 /UG=Hs.82962 thymidylate synthetase /FL=gb:BC002567.1 gb:NM_001071.1" NM_001071 thymidylate synthetase TYMS 7298 NM_001071 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006231 // dTMP biosynthetic process // inferred from electronic annotation /// 0006235 // dTTP biosynthetic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0019088 // immortalization of host cell by virus // inferred from electronic annotation /// 0019860 // uracil metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046078 // dUMP metabolic process // inferred from electronic annotation /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from electronic annotation /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051593 // response to folic acid // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060574 // intestinal epithelial cell maturation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0004799 // thymidylate synthase activity // traceable author statement /// 0005542 // folic acid binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 202590_s_at AL574319 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL574319 /FEA=EST /DB_XREF=gi:12934412 /DB_XREF=est:AL574319 /CLONE=CS0DI057YO23 (3 prime) /UG=Hs.92261 pyruvate dehydrogenase kinase, isoenzyme 2 /FL=gb:L42451.1 gb:NM_002611.1" AL574319 "pyruvate dehydrogenase kinase, isozyme 2" PDK2 5164 NM_001199898 /// NM_001199899 /// NM_001199900 /// NM_002611 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // traceable author statement /// 0006111 // regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006885 // regulation of pH // inferred from sequence or structural similarity /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // inferred from sequence or structural similarity /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0010565 // regulation of cellular ketone metabolic process // inferred from sequence or structural similarity /// 0010906 // regulation of glucose metabolic process // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031670 // cellular response to nutrient // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005967 // mitochondrial pyruvate dehydrogenase complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004740 // pyruvate dehydrogenase (acetyl-transferring) kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 202591_s_at NM_003143 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003143.1 /DEF=Homo sapiens single-stranded DNA-binding protein (SSBP), mRNA. /FEA=mRNA /GEN=SSBP /PROD=single-stranded DNA-binding protein /DB_XREF=gi:4507230 /UG=Hs.923 single-stranded DNA-binding protein /FL=gb:M94556.1 gb:NM_003143.1" NM_003143 "single-stranded DNA binding protein 1, mitochondrial" SSBP1 6742 NM_001256510 /// NM_001256511 /// NM_001256512 /// NM_001256513 /// NM_003143 /// NR_046269 /// XM_005250048 /// XM_005250049 /// XM_005250050 /// XM_005250051 0006260 // DNA replication // inferred from electronic annotation /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202592_at NM_001487 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001487.1 /DEF=Homo sapiens GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 (GCN5L1), mRNA. /FEA=mRNA /GEN=GCN5L1 /PROD=GCN5 (general control of amino-acid synthesis,yeast, homolog)-like 1 /DB_XREF=gi:4503954 /UG=Hs.94672 GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 /FL=gb:D64007.1 gb:NM_001487.1" NM_001487 "biogenesis of lysosomal organelles complex-1, subunit 1" BLOC1S1 2647 NM_001487 /// NR_037655 /// NR_037656 /// NR_037657 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0009060 // aerobic respiration // inferred from mutant phenotype /// 0018394 // peptidyl-lysine acetylation // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0032438 // melanosome organization // non-traceable author statement /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0060155 // platelet dense granule organization // non-traceable author statement /// 0061024 // membrane organization // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0031083 // BLOC-1 complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202593_s_at NM_016641 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016641.1 /DEF=Homo sapiens membrane interacting protein of RGS16 (MIR16), mRNA. /FEA=mRNA /GEN=MIR16 /PROD=membrane interacting protein of RGS16 /DB_XREF=gi:7706616 /UG=Hs.107014 membrane interacting protein of RGS16 /FL=gb:AF212862.1 gb:NM_016641.1" NM_016641 glycerophosphodiester phosphodiesterase 1 GDE1 51573 NM_016641 /// XM_005255355 0006071 // glycerol metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008889 // glycerophosphodiester phosphodiesterase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047395 // glycerophosphoinositol glycerophosphodiesterase activity // inferred from electronic annotation 202594_at NM_015344 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015344.1 /DEF=Homo sapiens MY047 protein (MY047), mRNA. /FEA=mRNA /GEN=MY047 /PROD=MY047 protein /DB_XREF=gi:7662509 /UG=Hs.11000 leptin receptor overlapping transcript-like 1 /FL=gb:BC000642.1 gb:AF063605.1 gb:AF161461.1 gb:NM_015344.1" NM_015344 leptin receptor overlapping transcript-like 1 LEPROTL1 23484 NM_001128208 /// NM_015344 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202595_s_at AF161461 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF161461.1 /DEF=Homo sapiens HSPC112 mRNA, complete cds. /FEA=mRNA /PROD=HSPC112 /DB_XREF=gi:6841445 /UG=Hs.11000 leptin receptor overlapping transcript-like 1 /FL=gb:BC000642.1 gb:AF063605.1 gb:AF161461.1 gb:NM_015344.1" AF161461 leptin receptor overlapping transcript-like 1 LEPROTL1 23484 NM_001128208 /// NM_015344 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202596_at BC000436 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000436.1 /DEF=Homo sapiens, endosulfine alpha, clone MGC:8394, mRNA, complete cds. /FEA=mRNA /PROD=endosulfine alpha /DB_XREF=gi:12653334 /UG=Hs.111680 endosulfine alpha /FL=gb:BC000436.1 gb:BC004461.1 gb:NM_004436.1 gb:AF157509.1" BC000436 endosulfine alpha ENSA 2029 NM_004436 /// NM_207042 /// NM_207043 /// NM_207044 /// NM_207045 /// NM_207046 /// NM_207047 /// NM_207168 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0000278 // mitotic cell cycle // traceable author statement /// 0006810 // transport // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007584 // response to nutrient // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0008200 // ion channel inhibitor activity // traceable author statement /// 0008601 // protein phosphatase type 2A regulator activity // inferred from sequence or structural similarity /// 0019212 // phosphatase inhibitor activity // inferred from sequence or structural similarity /// 0019870 // potassium channel inhibitor activity // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity 202597_at AU144284 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU144284 /FEA=EST /DB_XREF=gi:11005805 /DB_XREF=est:AU144284 /CLONE=HEMBA1001439 /UG=Hs.11801 interferon regulatory factor 6 /FL=gb:AF027292.1 gb:NM_006147.1 AU144284 interferon regulatory factor 6 IRF6 3664 NM_001206696 /// NM_006147 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060644 // mammary gland epithelial cell differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202598_at NM_005979 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005979.1 /DEF=Homo sapiens S100 calcium-binding protein A13 (S100A13), mRNA. /FEA=mRNA /GEN=S100A13 /PROD=S100 calcium-binding protein A13 /DB_XREF=gi:5174658 /UG=Hs.14331 S100 calcium-binding protein A13 /FL=gb:BC000632.1 gb:NM_005979.1" NM_005979 S100 calcium binding protein A13 S100A13 6284 NM_001024210 /// NM_001024211 /// NM_001024212 /// NM_001024213 /// NM_005979 /// XM_005245434 0006810 // transport // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043303 // mast cell degranulation // non-traceable author statement /// 0046688 // response to copper ion // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from mutant phenotype /// 0050703 // interleukin-1 alpha secretion // inferred from direct assay /// 0051602 // response to electrical stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0042629 // mast cell granule // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050786 // RAGE receptor binding // inferred from physical interaction 202599_s_at NM_003489 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003489.1 /DEF=Homo sapiens nuclear receptor interacting protein 1 (NRIP1), mRNA. /FEA=mRNA /GEN=NRIP1 /PROD=receptor interacting protein 140 /DB_XREF=gi:4505454 /UG=Hs.155017 nuclear receptor interacting protein 1 /FL=gb:NM_003489.1" NM_003489 nuclear receptor interacting protein 1 NRIP1 8204 NM_003489 /// XM_005261063 /// XM_005261065 /// XM_005261066 /// XM_006724054 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001543 // ovarian follicle rupture // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0030728 // ovulation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 202600_s_at AI824012 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI824012 /FEA=EST /DB_XREF=gi:5444683 /DB_XREF=est:wj29e06.x1 /CLONE=IMAGE:2404258 /UG=Hs.155017 nuclear receptor interacting protein 1 /FL=gb:NM_003489.1 AI824012 nuclear receptor interacting protein 1 NRIP1 8204 NM_003489 /// XM_005261063 /// XM_005261065 /// XM_005261066 /// XM_006724054 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001543 // ovarian follicle rupture // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0019915 // lipid storage // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0030728 // ovulation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from electronic annotation /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 202601_s_at AI373539 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI373539 /FEA=EST /DB_XREF=gi:4153405 /DB_XREF=est:qz46h02.x1 /CLONE=IMAGE:2029971 /UG=Hs.171595 HIV TAT specific factor 1 /FL=gb:U76992.1 gb:NM_014500.1 AI373539 HIV-1 Tat specific factor 1 HTATSF1 27336 NM_001163280 /// NM_014500 /// XM_005262404 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202602_s_at NM_014500 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014500.1 /DEF=Homo sapiens HIV TAT specific factor 1 (HTATSF1), mRNA. /FEA=mRNA /GEN=HTATSF1 /PROD=HIV TAT specific factor 1 /DB_XREF=gi:7657636 /UG=Hs.171595 HIV TAT specific factor 1 /FL=gb:U76992.1 gb:NM_014500.1" NM_014500 HIV-1 Tat specific factor 1 HTATSF1 27336 NM_001163280 /// NM_014500 /// XM_005262404 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202603_at N51370 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N51370 /FEA=EST /DB_XREF=gi:1192536 /DB_XREF=est:yz16d01.s1 /CLONE=IMAGE:283201 /UG=Hs.172028 a disintegrin and metalloproteinase domain 10 /FL=gb:AF009615.1 gb:NM_001110.1 N51370 ADAM metallopeptidase domain 10 ADAM10 102 NM_001110 /// XM_005254117 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0042117 // monocyte activation // inferred from mutant phenotype /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051089 // constitutive protein ectodomain proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay /// 0097197 // tetraspanin-enriched microdomain // inferred from direct assay 0004175 // endopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005102 // receptor binding // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202604_x_at NM_001110 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001110.1 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 10 (ADAM10), mRNA. /FEA=mRNA /GEN=ADAM10 /PROD=a disintegrin and metalloprotease domain 10 /DB_XREF=gi:4557250 /UG=Hs.172028 a disintegrin and metalloproteinase domain 10 /FL=gb:AF009615.1 gb:NM_001110.1" NM_001110 ADAM metallopeptidase domain 10 ADAM10 102 NM_001110 /// XM_005254117 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006509 // membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0010820 // positive regulation of T cell chemotaxis // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0042117 // monocyte activation // inferred from mutant phenotype /// 0051088 // PMA-inducible membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0051089 // constitutive protein ectodomain proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay /// 0097197 // tetraspanin-enriched microdomain // inferred from direct assay 0004175 // endopeptidase activity // inferred from sequence or structural similarity /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // non-traceable author statement /// 0005102 // receptor binding // non-traceable author statement /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // inferred from mutant phenotype /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 202605_at NM_000181 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000181.1 /DEF=Homo sapiens glucuronidase, beta (GUSB), mRNA. /FEA=mRNA /GEN=GUSB /PROD=glucuronidase, beta /DB_XREF=gi:4504222 /UG=Hs.183868 glucuronidase, beta /FL=gb:M15182.1 gb:NM_000181.1" NM_000181 "glucuronidase, beta" GUSB 2990 NM_000181 /// NM_001284290 /// NM_001293104 /// NM_001293105 /// NR_120531 /// XM_005250297 /// XR_242233 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004566 // beta-glucuronidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation" 202606_s_at NM_012290 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012290.1 /DEF=Homo sapiens tousled-like kinase 1 (TLK1), mRNA. /FEA=mRNA /GEN=TLK1 /PROD=tousled-like kinase 1 /DB_XREF=gi:6912719 /UG=Hs.18895 tousled-like kinase 1 /FL=gb:AB004885.1 gb:NM_012290.1 gb:AF246219.1" NM_012290 tousled-like kinase 1 TLK1 9874 NM_001136554 /// NM_001136555 /// NM_012290 /// XM_005246981 /// XM_006712883 0001672 // regulation of chromatin assembly or disassembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202607_at AL526632 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL526632 /FEA=EST /DB_XREF=gi:12790125 /DB_XREF=est:AL526632 /CLONE=CS0DC020YC21 (3 prime) /UG=Hs.20894 N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 1 /FL=gb:U36600.1 gb:NM_001543.1 gb:U17970.1 gb:U18918.1 AL526632 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 NDST1 3340 NM_001543 /// XM_005268433 /// XM_005268434 /// XM_005268435 /// XM_005268436 /// XM_005268437 /// XM_005268438 /// XM_005268439 /// XM_005268440 /// XM_005268441 /// XM_005268442 /// XM_006714782 /// XM_006714783 /// XR_245854 0000165 // MAPK cascade // inferred from electronic annotation /// 0000271 // polysaccharide biosynthetic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006477 // protein sulfation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048702 // embryonic neurocranium morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 202608_s_at NM_001543 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001543.1 /DEF=Homo sapiens N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 1 (NDST1), mRNA. /FEA=mRNA /GEN=NDST1 /PROD=N-deacetylaseN-sulfotransferase (heparanglucosaminyl) 1 /DB_XREF=gi:4505350 /UG=Hs.20894 N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 1 /FL=gb:U36600.1 gb:NM_001543.1 gb:U17970.1 gb:U18918.1" NM_001543 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 NDST1 3340 NM_001543 /// XM_005268433 /// XM_005268434 /// XM_005268435 /// XM_005268436 /// XM_005268437 /// XM_005268438 /// XM_005268439 /// XM_005268440 /// XM_005268441 /// XM_005268442 /// XM_006714782 /// XM_006714783 /// XR_245854 0000165 // MAPK cascade // inferred from electronic annotation /// 0000271 // polysaccharide biosynthetic process // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006477 // protein sulfation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0048702 // embryonic neurocranium morphogenesis // inferred from electronic annotation /// 0048703 // embryonic viscerocranium morphogenesis // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 202609_at NM_004447 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004447.1 /DEF=Homo sapiens epidermal growth factor receptor pathway substrate 8 (EPS8), mRNA. /FEA=mRNA /GEN=EPS8 /PROD=epidermal growth factor receptor pathwaysubstrate 8 /DB_XREF=gi:4758295 /UG=Hs.2132 epidermal growth factor receptor pathway substrate 8 /FL=gb:NM_004447.1 gb:U12535.1" NM_004447 epidermal growth factor receptor pathway substrate 8 EPS8 2059 NM_004447 /// XM_005253339 /// XM_005253340 /// XM_006719057 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010458 // exit from mitosis // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from sequence or structural similarity /// 0030832 // regulation of actin filament length // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0036336 // dendritic cell migration // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0070358 // actin polymerization-dependent cell motility // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from sequence or structural similarity /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from sequence or structural similarity 202610_s_at AF135802 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF135802.1 /DEF=Homo sapiens thyroid hormone receptor-associated protein complex component TRAP170 mRNA, complete cds. /FEA=mRNA /PROD=thyroid hormone receptor-associated proteincomplex component TRAP170 /DB_XREF=gi:4580325 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) /FL=gb:AF304448.1 gb:AB006651.1 gb:AF104256.1 gb:AF135802.1 gb:NM_004229.1" AF135802 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 202611_s_at AI971089 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI971089 /FEA=EST /DB_XREF=gi:5767915 /DB_XREF=est:wr23g11.x1 /CLONE=IMAGE:2488580 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) /FL=gb:AF304448.1 gb:AB006651.1 gb:AF104256.1 gb:AF135802.1 gb:NM_004229.1" AI971089 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 202612_s_at NM_004229 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004229.1 /DEF=Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) (CRSP2), mRNA. /FEA=mRNA /GEN=CRSP2 /PROD=cofactor required for Sp1 transcriptionalactivation, subunit 2 (150kD) /DB_XREF=gi:4758101 /UG=Hs.21586 cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) /FL=gb:AF304448.1 gb:AB006651.1 gb:AF104256.1 gb:AF135802.1 gb:NM_004229.1" NM_004229 mediator complex subunit 14 MED14 9282 NM_004229 /// XM_005272699 /// XM_005272700 /// XM_005272701 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 202613_at NM_001905 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001905.1 /DEF=Homo sapiens CTP synthase (CTPS), mRNA. /FEA=mRNA /GEN=CTPS /PROD=CTP synthase /DB_XREF=gi:4503132 /UG=Hs.251871 CTP synthase /FL=gb:NM_001905.1" NM_001905 CTP synthase 1 CTPS1 1503 NM_001905 /// XM_005270536 /// XM_006710390 /// XM_006710391 /// XR_426589 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0044210 // 'de novo' CTP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003883 // CTP synthase activity // not recorded /// 0003883 // CTP synthase activity // inferred from direct assay /// 0003883 // CTP synthase activity // inferred from genetic interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202614_at NM_006345 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006345.2 /DEF=Homo sapiens chromosome 4 open reading frame 1 (C4ORF1), mRNA. /FEA=mRNA /GEN=C4ORF1 /PROD=chromosome 4 open reading frame 1 /DB_XREF=gi:7656945 /UG=Hs.270956 chromosome 4 open reading frame 1 /FL=gb:AF006621.2 gb:NM_006345.2" NM_006345 "solute carrier family 30 (zinc transporter), member 9" SLC30A9 10463 NM_006345 "0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0008324 // cation transmembrane transporter activity // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation 202615_at BF222895 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF222895 /FEA=EST /DB_XREF=gi:11130072 /DB_XREF=est:7q24f10.x1 /CLONE=IMAGE:3699235 /UG=Hs.296261 guanine nucleotide binding protein (G protein), q polypeptide /FL=gb:U43083.1 gb:AF329284.1 gb:AF011496.1 gb:NM_002072.1" BF222895 "guanine nucleotide binding protein (G protein), q polypeptide" GNAQ 2776 NM_002072 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // not recorded /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007215 // glutamate receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016322 // neuron remodeling // inferred from electronic annotation /// 0021884 // forebrain neuron development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 202616_s_at AI631140 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI631140 /FEA=EST /DB_XREF=gi:4682470 /DB_XREF=est:ts93b07.x1 /CLONE=IMAGE:2238805 /UG=Hs.3239 methyl CpG binding protein 2 (Rett syndrome) /FL=gb:AF158180.1 gb:NM_004992.2 gb:L37298.1 AI631140 methyl CpG binding protein 2 MECP2 4204 NM_001110792 /// NM_004992 /// XM_005274681 /// XM_005274682 /// XM_005274683 /// XM_006724819 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006576 // cellular biogenic amine metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019230 // proprioception // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032048 // cardiolipin metabolic process // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050432 // catecholamine secretion // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation" 0000792 // heterochromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0010385 // double-stranded methylated DNA binding // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 202617_s_at NM_004992 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004992.2 /DEF=Homo sapiens methyl CpG binding protein 2 (Rett syndrome) (MECP2), mRNA. /FEA=mRNA /GEN=MECP2 /PROD=methyl CpG binding protein 2 /DB_XREF=gi:7710148 /UG=Hs.3239 methyl CpG binding protein 2 (Rett syndrome) /FL=gb:AF158180.1 gb:NM_004992.2 gb:L37298.1" NM_004992 methyl CpG binding protein 2 MECP2 4204 NM_001110792 /// NM_004992 /// XM_005274681 /// XM_005274682 /// XM_005274683 /// XM_006724819 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006576 // cellular biogenic amine metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019230 // proprioception // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032048 // cardiolipin metabolic process // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050432 // catecholamine secretion // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation" 0000792 // heterochromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0010385 // double-stranded methylated DNA binding // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 202618_s_at L37298 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L37298.1 /DEF=Homo sapiens methyl-CpG-binding protein (MeCP-2) mRNA, complete cds. /FEA=mRNA /GEN=MeCP-2 /PROD=methyl-CpG-binding protein /DB_XREF=gi:972764 /UG=Hs.3239 methyl CpG binding protein 2 (Rett syndrome) /FL=gb:AF158180.1 gb:NM_004992.2 gb:L37298.1" L37298 methyl CpG binding protein 2 MECP2 4204 NM_001110792 /// NM_004992 /// XM_005274681 /// XM_005274682 /// XM_005274683 /// XM_006724819 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001964 // startle response // inferred from electronic annotation /// 0001976 // neurological system process involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006020 // inositol metabolic process // inferred from electronic annotation /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c // inferred from electronic annotation /// 0006342 // chromatin silencing // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006576 // cellular biogenic amine metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009405 // pathogenesis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0019230 // proprioception // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032048 // cardiolipin metabolic process // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from electronic annotation /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0050432 // catecholamine secretion // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation" 0000792 // heterochromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // inferred from electronic annotation /// 0010385 // double-stranded methylated DNA binding // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 202619_s_at AI754404 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI754404 /FEA=EST /DB_XREF=gi:5132668 /DB_XREF=est:cr24g06.x1 /CLONE=HBMSC_cr24g06 /UG=Hs.41270 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 /FL=gb:U84573.1 gb:NM_000935.1" AI754404 "procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2" PLOD2 5352 NM_000935 /// NM_182943 /// XM_005247535 /// XM_005247536 0001666 // response to hypoxia // inferred from expression pattern /// 0006464 // cellular protein modification process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005506 // iron ion binding // inferred from electronic annotation /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 202620_s_at NM_000935 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000935.1 /DEF=Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 (PLOD2), mRNA. /FEA=mRNA /GEN=PLOD2 /PROD=procollagen-lysine, 2-oxoglutarate 5-dioxygenase(lysine hydroxylase) 2 /DB_XREF=gi:4505888 /UG=Hs.41270 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 /FL=gb:U84573.1 gb:NM_000935.1" NM_000935 "procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2" PLOD2 5352 NM_000935 /// NM_182943 /// XM_005247535 /// XM_005247536 0001666 // response to hypoxia // inferred from expression pattern /// 0006464 // cellular protein modification process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005581 // collagen trimer // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005506 // iron ion binding // inferred from electronic annotation /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 202621_at NM_001571 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001571.1 /DEF=Homo sapiens interferon regulatory factor 3 (IRF3), mRNA. /FEA=mRNA /GEN=IRF3 /PROD=interferon regulatory factor 3 /DB_XREF=gi:4504724 /UG=Hs.75254 interferon regulatory factor 3 /FL=gb:NM_001571.1" NM_001571 interferon regulatory factor 3 IRF3 3661 NM_001197122 /// NM_001197123 /// NM_001197124 /// NM_001197125 /// NM_001197126 /// NM_001197127 /// NM_001197128 /// NM_001571 /// NR_045568 /// XM_006723197 /// XM_006723198 /// XM_006723199 /// XM_006723200 /// XM_006723201 /// XM_006723202 /// XR_430199 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from sequence or structural similarity /// 0032728 // positive regulation of interferon-beta production // inferred from sequence or structural similarity /// 0032728 // positive regulation of interferon-beta production // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0039530 // MDA-5 signaling pathway // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0045358 // negative regulation of interferon-beta biosynthetic process // inferred from electronic annotation /// 0050689 // negative regulation of defense response to virus by host // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060340 // positive regulation of type I interferon-mediated signaling pathway // inferred from electronic annotation /// 0071359 // cellular response to dsRNA // inferred from electronic annotation /// 0071888 // macrophage apoptotic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 202622_s_at NM_002973 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002973.1 /DEF=Homo sapiens spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2) (SCA2), mRNA. /FEA=mRNA /GEN=SCA2 /PROD=ataxin 2 /DB_XREF=gi:4506794 /UG=Hs.76253 spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2) /FL=gb:U70323.1 gb:NM_002973.1" NM_002973 ataxin 2 ATXN2 6311 NM_002973 0002091 // negative regulation of receptor internalization // inferred from mutant phenotype /// 0006417 // regulation of translation // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016070 // RNA metabolic process // non-traceable author statement /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0033962 // cytoplasmic mRNA processing body assembly // inferred from mutant phenotype /// 0034063 // stress granule assembly // inferred from mutant phenotype /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0050658 // RNA transport // non-traceable author statement /// 0050905 // neuromuscular process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005844 // polysome // inferred from direct assay /// 0010494 // cytoplasmic stress granule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003723 // RNA binding // non-traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202623_at NM_018453 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018453.1 /DEF=Homo sapiens uncharacterized bone marrow protein BM036 (BM036), mRNA. /FEA=mRNA /GEN=BM036 /PROD=uncharacterized bone marrow protein BM036 /DB_XREF=gi:8922092 /UG=Hs.7731 uncharacterized bone marrow protein BM036 /FL=gb:BC001245.1 gb:AF217512.1 gb:NM_018453.1" NM_018453 E2F-associated phosphoprotein EAPP 55837 NM_018453 /// XM_005267858 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 202624_s_at NM_012295 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012295.1 /DEF=Homo sapiens calcineurin binding protein 1 (KIAA0330), mRNA. /FEA=mRNA /GEN=KIAA0330 /PROD=calcineurin binding protein 1 /DB_XREF=gi:6912457 /UG=Hs.7840 calcineurin binding protein 1 /FL=gb:AF072441.1 gb:NM_012295.1" NM_012295 calcineurin binding protein 1 CABIN1 23523 NM_001199281 /// NM_001201429 /// NM_012295 /// XM_005261415 /// XM_005261416 /// XM_005261417 /// XM_005261419 /// XM_005261420 /// XM_006724179 /// XM_006724180 /// XM_006724181 /// XM_006724182 /// XM_006724183 /// XM_006724184 /// XR_430404 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202625_at AI356412 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI356412 /FEA=EST /DB_XREF=gi:4108033 /DB_XREF=est:qz26h02.x1 /CLONE=IMAGE:2028051 /UG=Hs.80887 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog /FL=gb:NM_002350.1 AI356412 "LYN proto-oncogene, Src family tyrosine kinase" LYN 4067 NM_001111097 /// NM_002350 /// XM_005251233 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001817 // regulation of cytokine production // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // traceable author statement /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002431 // Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // traceable author statement /// 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0002576 // platelet degranulation // inferred from sequence or structural similarity /// 0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from sequence or structural similarity /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred by curator /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from sequence or structural similarity /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // inferred from sequence or structural similarity /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043304 // regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045646 // regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060369 // positive regulation of Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070304 // positive regulation of stress-activated protein kinase signaling cascade // inferred from direct assay /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070447 // positive regulation of oligodendrocyte progenitor proliferation // inferred from electronic annotation /// 0070667 // negative regulation of mast cell proliferation // inferred from sequence or structural similarity /// 0070668 // positive regulation of mast cell proliferation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0090025 // regulation of monocyte chemotaxis // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from sequence or structural similarity /// 1902532 // negative regulation of intracellular signal transduction // inferred from sequence or structural similarity /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034666 // integrin alpha2-beta1 complex // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 202626_s_at NM_002350 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002350.1 /DEF=Homo sapiens v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (LYN), mRNA. /FEA=mRNA /GEN=LYN /PROD=v-yes-1 Yamaguchi sarcoma viral related oncogenehomolog /DB_XREF=gi:4505054 /UG=Hs.80887 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog /FL=gb:NM_002350.1" NM_002350 "LYN proto-oncogene, Src family tyrosine kinase" LYN 4067 NM_001111097 /// NM_002350 /// XM_005251233 0001782 // B cell homeostasis // inferred from sequence or structural similarity /// 0001817 // regulation of cytokine production // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // traceable author statement /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0002431 // Fc receptor mediated stimulatory signaling pathway // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // inferred from sequence or structural similarity /// 0002513 // tolerance induction to self antigen // traceable author statement /// 0002553 // histamine secretion by mast cell // inferred from electronic annotation /// 0002576 // platelet degranulation // inferred from sequence or structural similarity /// 0002762 // negative regulation of myeloid leukocyte differentiation // inferred from electronic annotation /// 0002768 // immune response-regulating cell surface receptor signaling pathway // inferred from sequence or structural similarity /// 0002768 // immune response-regulating cell surface receptor signaling pathway // traceable author statement /// 0002774 // Fc receptor mediated inhibitory signaling pathway // inferred from sequence or structural similarity /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred by curator /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030262 // apoptotic nuclear changes // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031295 // T cell costimulation // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from sequence or structural similarity /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0033003 // regulation of mast cell activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from mutant phenotype /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // inferred from sequence or structural similarity /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042327 // positive regulation of phosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043304 // regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045646 // regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // traceable author statement /// 0050853 // B cell receptor signaling pathway // inferred from electronic annotation /// 0050855 // regulation of B cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from direct assay /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060369 // positive regulation of Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070304 // positive regulation of stress-activated protein kinase signaling cascade // inferred from direct assay /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070447 // positive regulation of oligodendrocyte progenitor proliferation // inferred from electronic annotation /// 0070667 // negative regulation of mast cell proliferation // inferred from sequence or structural similarity /// 0070668 // positive regulation of mast cell proliferation // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0090025 // regulation of monocyte chemotaxis // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 0097028 // dendritic cell differentiation // inferred from sequence or structural similarity /// 1902532 // negative regulation of intracellular signal transduction // inferred from sequence or structural similarity /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0034666 // integrin alpha2-beta1 complex // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043208 // glycosphingolipid binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from electronic annotation" 202627_s_at AL574210 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL574210 /FEA=EST /DB_XREF=gi:12934198 /DB_XREF=est:AL574210 /CLONE=CS0DI039YB02 (3 prime) /UG=Hs.82085 serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 /FL=gb:NM_000602.1 gb:M16006.1" AL574210 "serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" SERPINE1 5054 NM_000602 /// NM_001165413 "0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010469 // regulation of receptor activity // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from mutant phenotype /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from mutant phenotype /// 0030195 // negative regulation of blood coagulation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035491 // positive regulation of leukotriene production involved in inflammatory response // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from genetic interaction /// 0050829 // defense response to Gram-negative bacterium // inferred from genetic interaction /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0061044 // negative regulation of vascular wound healing // inferred from genetic interaction /// 0061045 // negative regulation of wound healing // inferred by curator /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0090026 // positive regulation of monocyte chemotaxis // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000098 // negative regulation of smooth muscle cell-matrix adhesion // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype" 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202628_s_at NM_000602 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000602.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), mRNA. /FEA=mRNA /GEN=SERPINE1 /PROD=serine (or cysteine) proteinase inhibitor, cladeE (nexin, plasminogen activator inhibitor type 1), member1 /DB_XREF=gi:10835158 /UG=Hs.82085 serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 /FL=gb:NM_000602.1 gb:M16006.1" NM_000602 "serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1" SERPINE1 5054 NM_000602 /// NM_001165413 "0001300 // chronological cell aging // inferred from expression pattern /// 0001525 // angiogenesis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010469 // regulation of receptor activity // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from mutant phenotype /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030194 // positive regulation of blood coagulation // inferred from mutant phenotype /// 0030195 // negative regulation of blood coagulation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from mutant phenotype /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0035491 // positive regulation of leukotriene production involved in inflammatory response // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from genetic interaction /// 0050829 // defense response to Gram-negative bacterium // inferred from genetic interaction /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay /// 0061044 // negative regulation of vascular wound healing // inferred from genetic interaction /// 0061045 // negative regulation of wound healing // inferred by curator /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0090026 // positive regulation of monocyte chemotaxis // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000098 // negative regulation of smooth muscle cell-matrix adhesion // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from mutant phenotype" 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement 0002020 // protease binding // inferred from physical interaction /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202629_at AV681579 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV681579 /FEA=EST /DB_XREF=gi:10283442 /DB_XREF=est:AV681579 /CLONE=GKBAFE05 /UG=Hs.84084 amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 /FL=gb:AF017782.1 gb:NM_006380.1 AV681579 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 APPBP2 10513 NM_001282476 /// NM_006380 /// XM_006721639 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202630_at AA046411 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA046411 /FEA=EST /DB_XREF=gi:1526376 /DB_XREF=est:zf47b09.s1 /CLONE=IMAGE:380057 /UG=Hs.84084 amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 /FL=gb:AF017782.1 gb:NM_006380.1 AA046411 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 APPBP2 10513 NM_001282476 /// NM_006380 /// XM_006721639 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202631_s_at NM_006380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006380.1 /DEF=Homo sapiens amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 (APPBP2), mRNA. /FEA=mRNA /GEN=APPBP2 /PROD=amyloid beta precursor protein (cytoplasmictail)-binding protein 2 /DB_XREF=gi:5453552 /UG=Hs.84084 amyloid beta precursor protein (cytoplasmic tail)-binding protein 2 /FL=gb:AF017782.1 gb:NM_006380.1" NM_006380 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 APPBP2 10513 NM_001282476 /// NM_006380 /// XM_006721639 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from direct assay 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202632_at NM_001383 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001383.1 /DEF=Homo sapiens diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1 (DPH2L1), mRNA. /FEA=mRNA /GEN=DPH2L1 /PROD=diptheria toxin resistance protein required fordiphthamide biosynthesis (Saccharomyces)-like 1 /DB_XREF=gi:4503360 /UG=Hs.84183 diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1 /FL=gb:BC003099.1 gb:AF321876.1 gb:U34880.1 gb:NM_001383.1" NM_001383 diphthamide biosynthesis 1 /// ovarian tumor suppressor candidate 2 DPH1 /// OVCA2 1801 /// 124641 NM_001383 /// NM_080822 0006412 // translation // traceable author statement /// 0008152 // metabolic process // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // non-traceable author statement 202633_at NM_007027 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007027.1 /DEF=Homo sapiens topoisomerase (DNA) II binding protein (TOPBP1), mRNA. /FEA=mRNA /GEN=TOPBP1 /PROD=topoisomerase (DNA) II binding protein /DB_XREF=gi:5902137 /UG=Hs.91417 topoisomerase (DNA) II binding protein /FL=gb:AB019397.1 gb:NM_007027.1" NM_007027 topoisomerase (DNA) II binding protein 1 TOPBP1 11073 NM_007027 /// XM_005247076 0006259 // DNA metabolic process // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from direct assay 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202634_at AL558030 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL558030 /FEA=EST /DB_XREF=gi:12902161 /DB_XREF=est:AL558030 /CLONE=CS0DJ002YJ02 (5 prime) /UG=Hs.150675 polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) /FL=gb:BC000806.1 gb:NM_005034.1 AL558030 "polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa" POLR2K 5440 NM_005034 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" "0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement" 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202635_s_at NM_005034 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005034.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) (POLR2K), mRNA. /FEA=mRNA /GEN=POLR2K /PROD=polymerase (RNA) II (DNA directed) polypeptide K(7.0kD) /DB_XREF=gi:4826923 /UG=Hs.150675 polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) /FL=gb:BC000806.1 gb:NM_005034.1" NM_005034 "polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa" POLR2K 5440 NM_005034 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006385 // transcription elongation from RNA polymerase III promoter // traceable author statement /// 0006386 // termination of RNA polymerase III transcription // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" "0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005666 // DNA-directed RNA polymerase III complex // not recorded /// 0005736 // DNA-directed RNA polymerase I complex // not recorded /// 0005829 // cytosol // traceable author statement" 0001054 // RNA polymerase I activity // not recorded /// 0001055 // RNA polymerase II activity // not recorded /// 0001056 // RNA polymerase III activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 202636_at NM_005667 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005667.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp103 in mouse (ZFP103), mRNA. /FEA=mRNA /GEN=ZFP103 /PROD=zinc finger protein homologous to Zfp103 inmouse /DB_XREF=gi:5031824 /UG=Hs.155968 zinc finger protein homologous to Zfp103 in mouse /FL=gb:D76444.1 gb:NM_005667.1" NM_005667 ring finger protein 103 RNF103 7844 NM_001198951 /// NM_001198952 /// NM_005667 0007417 // central nervous system development // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202637_s_at AI608725 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI608725 /FEA=EST /DB_XREF=gi:4617892 /DB_XREF=est:tw90b01.x1 /CLONE=IMAGE:2266921 /UG=Hs.168383 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor /FL=gb:M24283.1 gb:J03132.1 gb:NM_000201.1" AI608725 intercellular adhesion molecule 1 ICAM1 3383 NM_000201 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001910 // regulation of leukocyte mediated cytotoxicity // traceable author statement /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002291 // T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype /// 0002457 // T cell antigen processing and presentation // inferred from electronic annotation /// 0002693 // positive regulation of cellular extravasation // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from mutant phenotype /// 0007569 // cell aging // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010477 // response to sulfur dioxide // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044406 // adhesion of symbiont to host // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0001772 // immunological synapse // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202638_s_at NM_000201 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000201.1 /DEF=Homo sapiens intercellular adhesion molecule 1 (CD54), human rhinovirus receptor (ICAM1), mRNA. /FEA=mRNA /GEN=ICAM1 /PROD=intercellular adhesion molecule 1 precursor /DB_XREF=gi:4557877 /UG=Hs.168383 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor /FL=gb:M24283.1 gb:J03132.1 gb:NM_000201.1" NM_000201 intercellular adhesion molecule 1 ICAM1 3383 NM_000201 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001910 // regulation of leukocyte mediated cytotoxicity // traceable author statement /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0002291 // T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype /// 0002457 // T cell antigen processing and presentation // inferred from electronic annotation /// 0002693 // positive regulation of cellular extravasation // inferred from mutant phenotype /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from mutant phenotype /// 0007569 // cell aging // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010477 // response to sulfur dioxide // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044406 // adhesion of symbiont to host // inferred from direct assay /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046813 // receptor-mediated virion attachment to host cell // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // inferred from expression pattern /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051926 // negative regulation of calcium ion transport // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0061028 // establishment of endothelial barrier // inferred from genetic interaction /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071312 // cellular response to alkaloid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay 0001772 // immunological synapse // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202639_s_at AI689052 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI689052 /FEA=EST /DB_XREF=gi:4900346 /DB_XREF=est:tx81b08.x1 /CLONE=IMAGE:2275959 /UG=Hs.176657 RAN binding protein 3 /FL=gb:NM_003624.1 AI689052 RAN binding protein 3 RANBP3 8498 NM_003624 /// NM_007320 /// NM_007321 /// NM_007322 /// XM_005259664 /// XM_006722928 /// XM_006722929 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0070412 // R-SMAD binding // inferred from physical interaction 202640_s_at NM_003624 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003624.1 /DEF=Homo sapiens RAN binding protein 3 (RANBP3), transcript variant RANBP3-a, mRNA. /FEA=mRNA /GEN=RANBP3 /PROD=RAN binding protein 3, isoform RANBP3-a /DB_XREF=gi:4506408 /UG=Hs.176657 RAN binding protein 3 /FL=gb:NM_003624.1" NM_003624 RAN binding protein 3 RANBP3 8498 NM_003624 /// NM_007320 /// NM_007321 /// NM_007322 /// XM_005259664 /// XM_006722928 /// XM_006722929 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0070412 // R-SMAD binding // inferred from physical interaction 202641_at NM_004311 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004311.1 /DEF=Homo sapiens ADP-ribosylation factor-like 3 (ARL3), mRNA. /FEA=mRNA /GEN=ARL3 /PROD=ADP-ribosylation factor-like 3 /DB_XREF=gi:4757773 /UG=Hs.182215 ADP-ribosylation factor-like 3 /FL=gb:U07151.1 gb:NM_004311.1" NM_004311 ADP-ribosylation factor-like 3 ARL3 403 NM_004311 0000910 // cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0042073 // intraciliary transport // inferred from electronic annotation /// 0042461 // photoreceptor cell development // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072372 // primary cilium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0008017 // microtubule binding // inferred from direct assay /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202642_s_at NM_003496 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003496.1 /DEF=Homo sapiens transformationtranscription domain-associated protein (TRRAP), mRNA. /FEA=mRNA /GEN=TRRAP /PROD=transformationtranscription domain-associatedprotein /DB_XREF=gi:4507690 /UG=Hs.203952 transformationtranscription domain-associated protein /FL=gb:AF076974.1 gb:NM_003496.1" NM_003496 transformation/transcription domain-associated protein TRRAP 8295 NM_001244580 /// NM_003496 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // non-traceable author statement /// 0016578 // histone deubiquitination // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay" 0000125 // PCAF complex // non-traceable author statement /// 0000812 // Swr1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay "0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 202643_s_at AI738896 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI738896 /FEA=EST /DB_XREF=gi:5100877 /DB_XREF=est:wi22g02.x1 /CLONE=IMAGE:2391026 /UG=Hs.211600 tumor necrosis factor, alpha-induced protein 3 /FL=gb:M59465.1 gb:NM_006290.1" AI738896 "tumor necrosis factor, alpha-induced protein 3" TNFAIP3 7128 NM_001270507 /// NM_001270508 /// NM_006290 /// XM_005267119 /// XM_006715555 "0001922 // B-1 B cell homeostasis // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002677 // negative regulation of chronic inflammatory response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // non-traceable author statement /// 0034140 // negative regulation of toll-like receptor 3 signaling pathway // inferred from direct assay /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // non-traceable author statement /// 0034148 // negative regulation of toll-like receptor 5 signaling pathway // inferred from electronic annotation /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // non-traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050691 // regulation of defense response to virus by host // non-traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050869 // negative regulation of B cell activation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // non-traceable author statement /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0061043 // regulation of vascular wound healing // non-traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070429 // negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070433 // negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from electronic annotation /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0072573 // tolerance induction to lipopolysaccharide // inferred from mutant phenotype /// 0090291 // negative regulation of osteoclast proliferation // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2000349 // negative regulation of CD40 signaling pathway // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202644_s_at NM_006290 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006290.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 3 (TNFAIP3), mRNA. /FEA=mRNA /GEN=TNFAIP3 /PROD=tumor necrosis factor, alpha-induced protein 3 /DB_XREF=gi:5454131 /UG=Hs.211600 tumor necrosis factor, alpha-induced protein 3 /FL=gb:M59465.1 gb:NM_006290.1" NM_006290 "tumor necrosis factor, alpha-induced protein 3" TNFAIP3 7128 NM_001270507 /// NM_001270508 /// NM_006290 /// XM_005267119 /// XM_006715555 "0001922 // B-1 B cell homeostasis // inferred from sequence or structural similarity /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0002634 // regulation of germinal center formation // inferred from sequence or structural similarity /// 0002677 // negative regulation of chronic inflammatory response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032703 // negative regulation of interleukin-2 production // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0034136 // negative regulation of toll-like receptor 2 signaling pathway // non-traceable author statement /// 0034140 // negative regulation of toll-like receptor 3 signaling pathway // inferred from direct assay /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // non-traceable author statement /// 0034148 // negative regulation of toll-like receptor 5 signaling pathway // inferred from electronic annotation /// 0035871 // protein K11-linked deubiquitination // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // non-traceable author statement /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050691 // regulation of defense response to virus by host // non-traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050869 // negative regulation of B cell activation // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // non-traceable author statement /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0061043 // regulation of vascular wound healing // non-traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement /// 0070429 // negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway // inferred from electronic annotation /// 0070433 // negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway // inferred from electronic annotation /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0072573 // tolerance induction to lipopolysaccharide // inferred from mutant phenotype /// 0090291 // negative regulation of osteoclast proliferation // non-traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2000349 // negative regulation of CD40 signaling pathway // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202645_s_at NM_000244 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000244.1 /DEF=Homo sapiens multiple endocrine neoplasia I (MEN1), mRNA. /FEA=mRNA /GEN=MEN1 /PROD=multiple endocrine neoplasia I /DB_XREF=gi:4557744 /UG=Hs.24297 multiple endocrine neoplasia I /FL=gb:U93236.1 gb:NM_000244.1" NM_000244 multiple endocrine neoplasia I MEN1 4221 NM_000244 /// NM_130799 /// NM_130800 /// NM_130801 /// NM_130802 /// NM_130803 /// NM_130804 /// XM_005274001 /// XM_005274002 /// XM_005274003 /// XM_006718557 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000165 // MAPK cascade // inferred from direct assay /// 0001503 // ossification // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from genetic interaction /// 0006281 // DNA repair // non-traceable author statement /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay /// 0009790 // embryo development // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0031062 // positive regulation of histone methylation // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from direct assay /// 0032925 // regulation of activin receptor signaling pathway // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from genetic interaction /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046329 // negative regulation of JNK cascade // inferred from direct assay /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from mutant phenotype /// 0060021 // palate development // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation" 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay "0000400 // four-way junction DNA binding // inferred from direct assay /// 0000403 // Y-form DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0018024 // histone-lysine N-methyltransferase activity // inferred from direct assay /// 0030674 // protein binding, bridging // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction" 202646_s_at AA167775 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA167775 /FEA=EST /DB_XREF=gi:1744943 /DB_XREF=est:zq40g07.s1 /CLONE=IMAGE:632220 /UG=Hs.260523 neuroblastoma RAS viral (v-ras) oncogene homolog /FL=gb:BC005219.1 gb:NM_002524.2 AA167775 "cold shock domain containing E1, RNA-binding" CSDE1 7812 NM_001007553 /// NM_001130523 /// NM_001242891 /// NM_001242892 /// NM_001242893 /// NM_007158 "0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0070966 // nuclear-transcribed mRNA catabolic process, no-go decay // inferred from mutant phenotype" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070937 // CRD-mediated mRNA stability complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202647_s_at NM_002524 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002524.2 /DEF=Homo sapiens neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS), mRNA. /FEA=mRNA /GEN=NRAS /PROD=neuroblastoma RAS viral (v-ras) oncogenehomolog /DB_XREF=gi:6006027 /UG=Hs.260523 neuroblastoma RAS viral (v-ras) oncogene homolog /FL=gb:BC005219.1 gb:NM_002524.2" NM_002524 neuroblastoma RAS viral (v-ras) oncogene homolog NRAS 4893 NM_002524 "0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 202648_at BC000023 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BC000023.1 /DEF=Homo sapiens, ribosomal protein S19, clone MGC:1630, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein S19 /DB_XREF=gi:12652562 /UG=Hs.298262 ribosomal protein S19 /FL=gb:BC000023.1 gb:M81757.1 gb:NM_001022.1" BC000023 transcription factor 3 TCF3 6929 NM_001136139 /// NM_003200 /// XM_005259620 /// XM_006722852 /// XM_006722853 /// XM_006722854 /// XM_006722855 /// XM_006722856 /// XM_006722857 /// XM_006722858 /// XM_006722859 /// XM_006722860 /// XM_006722861 /// XM_006722862 /// XM_006722863 /// XR_430150 /// XR_430151 /// XR_430152 /// XR_430153 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from direct assay /// 0002326 // B cell lineage commitment // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0030098 // lymphocyte differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030183 // B cell differentiation // non-traceable author statement /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033152 // immunoglobulin V(D)J recombination // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043966 // histone H3 acetylation // inferred from electronic annotation /// 0043967 // histone H4 acetylation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048468 // cell development // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay" 0000788 // nuclear nucleosome // inferred from electronic annotation /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 0070888 // E-box binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 202649_x_at NM_001022 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001022.1 /DEF=Homo sapiens ribosomal protein S19 (RPS19), mRNA. /FEA=mRNA /GEN=RPS19 /PROD=ribosomal protein S19 /DB_XREF=gi:4506694 /UG=Hs.298262 ribosomal protein S19 /FL=gb:BC000023.1 gb:M81757.1 gb:NM_001022.1" NM_001022 ribosomal protein S19 RPS19 6223 NM_001022 "0000028 // ribosomal small subunit assembly // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from mutant phenotype /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0007000 // nucleolus organization // inferred from mutant phenotype /// 0009991 // response to extracellular stimulus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0030218 // erythrocyte differentiation // inferred from mutant phenotype /// 0030490 // maturation of SSU-rRNA // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0051272 // positive regulation of cellular component movement // traceable author statement /// 0060265 // positive regulation of respiratory burst involved in inflammatory response // inferred from direct assay /// 0060266 // negative regulation of respiratory burst involved in inflammatory response // inferred from direct assay" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 202650_s_at NM_014738 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014738.1 /DEF=Homo sapiens KIAA0195 gene product (KIAA0195), mRNA. /FEA=mRNA /GEN=KIAA0195 /PROD=KIAA0195 gene product /DB_XREF=gi:7661985 /UG=Hs.301132 KIAA0195 gene product /FL=gb:D83779.1 gb:NM_014738.1" NM_014738 KIAA0195 /// microRNA 6785 KIAA0195 /// MIR6785 9772 /// 102466911 NM_014738 /// NR_106843 /// XM_005257863 /// XM_005257864 /// XM_005257865 /// XM_005257866 /// XM_005257867 /// XM_005257868 /// XM_006722200 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202651_at NM_014873 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014873.1 /DEF=Homo sapiens KIAA0205 gene product (KIAA0205), mRNA. /FEA=mRNA /GEN=KIAA0205 /PROD=KIAA0205 gene product /DB_XREF=gi:7661995 /UG=Hs.3610 KIAA0205 gene product /FL=gb:D86960.1 gb:NM_014873.1" NM_014873 lysophosphatidylglycerol acyltransferase 1 LPGAT1 9926 NM_014873 /// XM_005273362 /// XM_005273363 /// XM_005273364 /// XM_006711695 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation" 202652_at NM_001164 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001164.1 /DEF=Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), mRNA. /FEA=mRNA /GEN=APBB1 /PROD=amyloid beta (A4) precursor protein-binding,family B, member 1 (Fe65) /DB_XREF=gi:4502130 /UG=Hs.3763 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) /FL=gb:L77864.1 gb:NM_001164.1" NM_001164 "amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)" APBB1 322 NM_001164 /// NM_001257319 /// NM_001257320 /// NM_001257321 /// NM_001257322 /// NM_001257323 /// NM_001257324 /// NM_001257325 /// NM_001257326 /// NM_145689 /// NR_047512 /// XM_006718209 /// XM_006718210 /// XM_006718211 /// XM_006718212 /// XM_006718213 /// XM_006718214 /// XM_006718215 /// XM_006718216 "0001764 // neuron migration // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0007409 // axonogenesis // non-traceable author statement /// 0007411 // axon guidance // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from sequence or structural similarity /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0050760 // negative regulation of thymidylate synthase biosynthetic process // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0001540 // beta-amyloid binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0042393 // histone binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from physical interaction 202653_s_at BC003404 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BC003404.1 /DEF=Homo sapiens, hypothetical protein DKFZp586F1122 similar to axotrophin, clone IMAGE:3449089, mRNA, partial cds. /FEA=mRNA /PROD=hypothetical protein DKFZp586F1122 similar toaxotrophin /DB_XREF=gi:13097302 /UG=Hs.5306 hypothetical protein DKFZp586F1122 similar to axotrophin /FL=gb:NM_022826.1" BC003404 "membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase" 7-Mar 64844 NM_001282805 /// NM_001282806 /// NM_001282807 /// NM_022826 /// XM_005246773 /// XM_005246774 /// XR_427106 0006909 // phagocytosis // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202654_x_at NM_022826 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022826.1 /DEF=Homo sapiens hypothetical protein DKFZp586F1122 similar to axotrophin (DKFZP586F1122), mRNA. /FEA=mRNA /GEN=DKFZP586F1122 /PROD=hypothetical protein DKFZp586F1122 similar toaxotrophin /DB_XREF=gi:12383065 /UG=Hs.5306 hypothetical protein DKFZp586F1122 similar to axotrophin /FL=gb:NM_022826.1" NM_022826 "membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase" 7-Mar 64844 NM_001282805 /// NM_001282806 /// NM_001282807 /// NM_022826 /// XM_005246773 /// XM_005246774 /// XR_427106 0006909 // phagocytosis // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0030175 // filopodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202655_at NM_006010 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006010.1 /DEF=Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA. /FEA=mRNA /GEN=ARMET /PROD=arginine-rich protein /DB_XREF=gi:5174392 /UG=Hs.75412 arginine-rich, mutated in early stage tumors /FL=gb:M83751.1 gb:NM_006010.1" NM_006010 mesencephalic astrocyte-derived neurotrophic factor MANF 7873 NM_006010 0002014 // vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0008083 // growth factor activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202656_s_at BG107456 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG107456 /FEA=EST /DB_XREF=gi:12601302 /DB_XREF=est:602277568F1 /CLONE=IMAGE:4365352 /UG=Hs.77293 KIAA0127 gene product /FL=gb:D50917.1 gb:NM_014755.1 BG107456 SERTA domain containing 2 SERTAD2 9792 NM_014755 /// XM_005264669 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202657_s_at NM_014755 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014755.1 /DEF=Homo sapiens KIAA0127 gene product (KIAA0127), mRNA. /FEA=mRNA /GEN=KIAA0127 /PROD=KIAA0127 gene product /DB_XREF=gi:7661925 /UG=Hs.77293 KIAA0127 gene product /FL=gb:D50917.1 gb:NM_014755.1" NM_014755 SERTA domain containing 2 SERTAD2 9792 NM_014755 /// XM_005264669 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202658_at NM_003846 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003846.1 /DEF=Homo sapiens peroxisomal biogenesis factor 11B (PEX11B), mRNA. /FEA=mRNA /GEN=PEX11B /PROD=peroxisomal biogenesis factor 11B /DB_XREF=gi:4505718 /UG=Hs.83023 peroxisomal biogenesis factor 11B /FL=gb:AF093670.1 gb:AB018080.1 gb:NM_003846.1" NM_003846 peroxisomal biogenesis factor 11 beta PEX11B 8799 NM_001184795 /// NM_003846 /// NR_073491 /// NR_073492 /// NR_073493 0007031 // peroxisome organization // inferred from direct assay /// 0007031 // peroxisome organization // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0016559 // peroxisome fission // inferred from direct assay /// 0044375 // regulation of peroxisome size // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005779 // integral component of peroxisomal membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 202659_at NM_002801 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002801.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 10 (PSMB10), mRNA. /FEA=mRNA /GEN=PSMB10 /PROD=proteasome (prosome, macropain) subunit, betatype, 10 /DB_XREF=gi:4506190 /UG=Hs.9661 proteasome (prosome, macropain) subunit, beta type, 10 /FL=gb:NM_002801.1" NM_002801 "proteasome (prosome, macropain) subunit, beta type, 10" PSMB10 5699 NM_002801 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202660_at AA834576 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA834576 /FEA=EST /DB_XREF=gi:2908175 /DB_XREF=est:od63f10.s1 /CLONE=IMAGE:1372651 /UG=Hs.238272 inositol 1,4,5-triphosphate receptor, type 2 /FL=gb:D26350.1 gb:NM_002223.1" AA834576 "inositol 1,4,5-trisphosphate receptor, type 2" ITPR2 3709 NM_002223 /// XM_006719064 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from mutant phenotype /// 0043235 // receptor complex // inferred from direct assay "0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0015278 // calcium-release channel activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation" 202661_at AI963873 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI963873 /FEA=EST /DB_XREF=gi:5756586 /DB_XREF=est:wt86b08.x1 /CLONE=IMAGE:2514327 /UG=Hs.238272 inositol 1,4,5-triphosphate receptor, type 2 /FL=gb:D26350.1 gb:NM_002223.1" AI963873 "inositol 1,4,5-trisphosphate receptor, type 2" ITPR2 3709 NM_002223 /// XM_006719064 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from mutant phenotype /// 0043235 // receptor complex // inferred from direct assay "0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0015278 // calcium-release channel activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation" 202662_s_at NM_002223 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002223.1 /DEF=Homo sapiens inositol 1,4,5-triphosphate receptor, type 2 (ITPR2), mRNA. /FEA=mRNA /GEN=ITPR2 /PROD=inositol 1,4,5-triphosphate receptor, type 2 /DB_XREF=gi:4504792 /UG=Hs.238272 inositol 1,4,5-triphosphate receptor, type 2 /FL=gb:D26350.1 gb:NM_002223.1" NM_002223 "inositol 1,4,5-trisphosphate receptor, type 2" ITPR2 3709 NM_002223 /// XM_006719064 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0033017 // sarcoplasmic reticulum membrane // inferred from mutant phenotype /// 0043235 // receptor complex // inferred from direct assay "0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0015278 // calcium-release channel activity // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation" 202663_at AI005043 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI005043 /FEA=EST /DB_XREF=gi:3214553 /DB_XREF=est:ou91c11.x1 /CLONE=IMAGE:1635188 /UG=Hs.24143 Wiskott-Aldrich syndrome protein interacting protein /FL=gb:NM_003387.2 AI005043 "WAS/WASL interacting protein family, member 1" WIPF1 7456 NM_001077269 /// NM_003387 /// XM_006712727 0006461 // protein complex assembly // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // traceable author statement 202664_at AW058622 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW058622 /FEA=EST /DB_XREF=gi:5934261 /DB_XREF=est:wy59c01.x1 /CLONE=IMAGE:2552832 /UG=Hs.24143 Wiskott-Aldrich syndrome protein interacting protein /FL=gb:NM_003387.2 AW058622 "WAS/WASL interacting protein family, member 1" WIPF1 7456 NM_001077269 /// NM_003387 /// XM_006712727 0006461 // protein complex assembly // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // traceable author statement 202665_s_at NM_003387 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003387.2 /DEF=Homo sapiens Wiskott-Aldrich syndrome protein interacting protein (WASPIP), mRNA. /FEA=mRNA /GEN=WASPIP /PROD=WASP-interacting protein /DB_XREF=gi:8400739 /UG=Hs.24143 Wiskott-Aldrich syndrome protein interacting protein /FL=gb:NM_003387.2" NM_003387 "WAS/WASL interacting protein family, member 1" WIPF1 7456 NM_001077269 /// NM_003387 /// XM_006712727 0006461 // protein complex assembly // traceable author statement /// 0008154 // actin polymerization or depolymerization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051707 // response to other organism // inferred from electronic annotation 0001726 // ruffle // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // traceable author statement 202666_s_at NM_004301 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004301.1 /DEF=Homo sapiens BAF53 (BAF53A), mRNA. /FEA=mRNA /GEN=BAF53A /PROD=BAF53a /DB_XREF=gi:4757717 /UG=Hs.274350 BAF53 /FL=gb:AL136608.1 gb:BC001391.1 gb:BC000949.2 gb:AF041474.1 gb:AB015907.1 gb:NM_004301.1" NM_004301 actin-like 6A ACTL6A 86 NM_004301 /// NM_177989 /// NM_178042 "0003407 // neural retina development // inferred from expression pattern /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031492 // nucleosomal DNA binding // inferred from direct assay 202667_s_at NM_006979 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006979.1 /DEF=Homo sapiens HLA class II region expressed gene KE4 (HKE4), mRNA. /FEA=mRNA /GEN=HKE4 /PROD=HLA class II region expressed gene KE4 /DB_XREF=gi:5901935 /UG=Hs.278721 HLA class II region expressed gene KE4 /FL=gb:D82060.1 gb:NM_006979.1" NM_006979 "solute carrier family 39 (zinc transporter), member 7" SLC39A7 7922 NM_001077516 /// NM_001288777 /// NM_006979 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006829 // zinc ion transport // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0046873 // metal ion transmembrane transporter activity // inferred from electronic annotation 202668_at BF001670 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF001670 /FEA=EST /DB_XREF=gi:10701945 /DB_XREF=est:7g91e06.x1 /CLONE=IMAGE:3313858 /UG=Hs.30942 ephrin-B2 /FL=gb:U81262.1 gb:NM_004093.1 gb:L38734.1 gb:U16797.1 BF001670 ephrin-B2 EFNB2 1948 NM_004093 0001525 // angiogenesis // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010839 // negative regulation of keratinocyte proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from direct assay /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from sequence or structural similarity 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction 202669_s_at U16797 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U16797.1 /DEF=Human LERK-5 (EPLG5) mRNA, complete cds. /FEA=mRNA /GEN=EPLG5 /PROD=LERK-5 /DB_XREF=gi:902370 /UG=Hs.30942 ephrin-B2 /FL=gb:U81262.1 gb:NM_004093.1 gb:L38734.1 gb:U16797.1" U16797 ephrin-B2 EFNB2 1948 NM_004093 0001525 // angiogenesis // inferred from electronic annotation /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010839 // negative regulation of keratinocyte proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from direct assay /// 2000727 // positive regulation of cardiac muscle cell differentiation // inferred from sequence or structural similarity 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // inferred from physical interaction 202670_at AI571419 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI571419 /FEA=EST /DB_XREF=gi:4534793 /DB_XREF=est:tn45h10.x1 /CLONE=IMAGE:2170627 /UG=Hs.3446 mitogen-activated protein kinase kinase 1 /FL=gb:L05624.1 gb:NM_002755.1 AI571419 mitogen-activated protein kinase kinase 1 MAP2K1 5604 NM_002755 /// XM_005254541 /// XM_006720608 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003056 // regulation of vascular smooth muscle contraction // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0034111 // negative regulation of homotypic cell-cell adhesion // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0047496 // vesicle transport along microtubule // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048313 // Golgi inheritance // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048870 // cell motility // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060674 // placenta blood vessel development // inferred from electronic annotation /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 0090398 // cellular senescence // inferred from mutant phenotype /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005816 // spindle pole body // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004728 // receptor signaling protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // inferred from direct assay" 202671_s_at NM_003681 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003681.1 /DEF=Homo sapiens pyridoxal (pyridoxine, vitamin B6) kinase (PDXK), mRNA. /FEA=mRNA /GEN=PDXK /PROD=pyridoxal kinase /DB_XREF=gi:4505700 /UG=Hs.38041 pyridoxal (pyridoxine, vitamin B6) kinase /FL=gb:BC000123.1 gb:U89606.1 gb:NM_003681.1" NM_003681 "pyridoxal (pyridoxine, vitamin B6) kinase" PDXK 8566 NM_003681 /// NM_021941 /// XM_005261195 /// XM_005261196 /// XM_005261198 /// XM_005261199 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from direct assay /// 0009443 // pyridoxal 5'-phosphate salvage // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042816 // vitamin B6 metabolic process // inferred by curator /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0042823 // pyridoxal phosphate biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0008478 // pyridoxal kinase activity // inferred from direct assay /// 0008478 // pyridoxal kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0030955 // potassium ion binding // inferred from direct assay /// 0031402 // sodium ion binding // inferred from direct assay /// 0031403 // lithium ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202672_s_at NM_001674 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001674.1 /DEF=Homo sapiens activating transcription factor 3 (ATF3), mRNA. /FEA=mRNA /GEN=ATF3 /PROD=activating transcription factor 3 long isoform /DB_XREF=gi:4502262 /UG=Hs.460 activating transcription factor 3 /FL=gb:L19871.1 gb:NM_001674.1" NM_001674 activating transcription factor 3 ATF3 467 NM_001030287 /// NM_001040619 /// NM_001206484 /// NM_001206485 /// NM_001206486 /// NM_001206488 /// NM_001674 /// NM_004024 /// XM_005273146 "0006094 // gluconeogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202673_at NM_003859 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003859.1 /DEF=Homo sapiens dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit (DPM1), mRNA. /FEA=mRNA /GEN=DPM1 /PROD=dolichyl-phosphate mannosyltransferasepolypeptide 1 /DB_XREF=gi:4503362 /UG=Hs.5085 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit /FL=gb:D86198.1 gb:NM_003859.1" NM_003859 "dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit" DPM1 8813 NM_003859 /// XM_005260600 /// XM_005260601 /// XM_005260602 /// XR_244156 0006486 // protein glycosylation // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019348 // dolichol metabolic process // inferred from direct assay /// 0019673 // GDP-mannose metabolic process // inferred from electronic annotation /// 0035268 // protein mannosylation // inferred from direct assay /// 0035269 // protein O-linked mannosylation // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0033185 // dolichol-phosphate-mannose synthase complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004169 // dolichyl-phosphate-mannose-protein mannosyltransferase activity // inferred from direct assay /// 0004582 // dolichyl-phosphate beta-D-mannosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043178 // alcohol binding // inferred from electronic annotation" 202674_s_at NM_005358 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005358.2 /DEF=Homo sapiens LIM domain only 7 (LMO7), mRNA. /FEA=mRNA /GEN=LMO7 /PROD=LIM domain only 7 isoform a /DB_XREF=gi:7369018 /UG=Hs.5978 LIM domain only 7 /FL=gb:AF144237.1 gb:NM_005358.2" NM_005358 LIM domain 7 LMO7 4008 NM_005358 /// NM_015842 /// NM_015843 /// XM_005266381 /// XM_005266383 /// XM_005266387 /// XM_005266389 /// XM_005266391 /// XM_005266392 /// XM_005266396 /// XM_005266397 /// XM_006719810 /// XM_006719811 /// XM_006719812 /// XM_006719813 /// XM_006719814 /// XM_006719815 /// XM_006719816 /// XM_006719817 /// XM_006719818 /// XM_006719819 /// XM_006719820 /// XM_006719821 /// XM_006719822 /// XM_006719823 /// XM_006719824 /// XM_006719825 /// XM_006719826 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202675_at NM_003000 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003000.1 /DEF=Homo sapiens succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHB /PROD=succinate dehydrogenase complex, subunit B, ironsulfur (Ip) /DB_XREF=gi:9257241 /UG=Hs.64 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) /FL=gb:U17248.1 gb:NM_003000.1" NM_003000 "succinate dehydrogenase complex, subunit B, iron sulfur (Ip)" SDHB 6390 NM_003000 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005749 // mitochondrial respiratory chain complex II // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005515 // protein binding // inferred from physical interaction /// 0008177 // succinate dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048039 // ubiquinone binding // inferred from sequence or structural similarity /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from sequence or structural similarity /// 0051538 // 3 iron, 4 sulfur cluster binding // inferred from sequence or structural similarity /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from sequence or structural similarity" 202676_x_at NM_006712 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006712.1 /DEF=Homo sapiens Fas-activated serinethreonine kinase (FASTK), mRNA. /FEA=mRNA /GEN=FASTK /PROD=Fas-activated serinethreonine kinase /DB_XREF=gi:5729821 /UG=Hs.75087 Fas-activated serinethreonine kinase /FL=gb:NM_006712.1" NM_006712 Fas-activated serine/threonine kinase FASTK 10922 NM_001258461 /// NM_006712 /// NM_033015 /// XM_005249932 /// XM_005249933 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033867 // Fas-activated serine/threonine kinase activity // inferred from electronic annotation 202677_at NM_002890 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002890.1 /DEF=Homo sapiens RAS p21 protein activator (GTPase activating protein) 1 (RASA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=RASA1 /PROD=RAS p21 protein activator 1, isoform 1 /DB_XREF=gi:4506430 /UG=Hs.758 RAS p21 protein activator (GTPase activating protein) 1 /FL=gb:M23379.1 gb:NM_002890.1" NM_002890 RAS p21 protein activator (GTPase activating protein) 1 RASA1 5921 NM_002890 /// NM_022650 0000281 // mitotic cytokinesis // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0008360 // regulation of cell shape // non-traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0030833 // regulation of actin filament polymerization // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // not recorded /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051252 // regulation of RNA metabolic process // non-traceable author statement 0001726 // ruffle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0001948 // glycoprotein binding // inferred from physical interaction /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // not recorded /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019870 // potassium channel inhibitor activity // non-traceable author statement /// 0051020 // GTPase binding // inferred from physical interaction 202678_at NM_004492 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004492.1 /DEF=Homo sapiens general transcription factor IIA, 2 (12kD subunit) (GTF2A2), mRNA. /FEA=mRNA /GEN=GTF2A2 /PROD=general transcription factor IIA, 2 (12kDsubunit) /DB_XREF=gi:4758485 /UG=Hs.76362 general transcription factor IIA, 2 (12kD subunit) /FL=gb:BC000287.1 gb:BC001919.1 gb:U21242.1 gb:NM_004492.1 gb:U14193.1" NM_004492 "general transcription factor IIA, 2, 12kDa" GTF2A2 2958 NM_004492 /// XM_005254324 /// XM_005254325 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051123 // RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005672 // transcription factor TFIIA complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0001103 // RNA polymerase II repressing transcription factor binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017025 // TBP-class protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 202679_at NM_000271 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000271.1 /DEF=Homo sapiens Niemann-Pick disease, type C1 (NPC1), mRNA. /FEA=mRNA /GEN=NPC1 /PROD=Niemann-Pick disease, type C1 /DB_XREF=gi:4557802 /UG=Hs.76918 Niemann-Pick disease, type C1 /FL=gb:AF002020.1 gb:NM_000271.1" NM_000271 "Niemann-Pick disease, type C1" NPC1 4864 NM_000271 /// XM_005258277 /// XM_005258278 /// XM_005258279 /// XM_006722479 0006486 // protein glycosylation // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006914 // autophagy // inferred from genetic interaction /// 0007041 // lysosomal transport // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from sequence or structural similarity /// 0016242 // negative regulation of macroautophagy // inferred from electronic annotation /// 0030301 // cholesterol transport // inferred from direct assay /// 0031579 // membrane raft organization // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071404 // cellular response to low-density lipoprotein particle stimulus // inferred from electronic annotation /// 0090150 // establishment of protein localization to membrane // inferred from direct assay 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008158 // hedgehog receptor activity // inferred from electronic annotation /// 0015248 // sterol transporter activity // traceable author statement /// 0015485 // cholesterol binding // inferred from direct assay 202680_at NM_002095 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002095.1 /DEF=Homo sapiens general transcription factor IIE, polypeptide 2 (beta subunit, 34kD) (GTF2E2), mRNA. /FEA=mRNA /GEN=GTF2E2 /PROD=general transcription factor IIE, polypeptide 2(beta subunit, 34kD) /DB_XREF=gi:4504194 /UG=Hs.77100 general transcription factor IIE, polypeptide 2 (beta subunit, 34kD) /FL=gb:NM_002095.1" NM_002095 "general transcription factor IIE, polypeptide 2, beta 34kDa" GTF2E2 2961 NM_002095 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005673 // transcription factor TFIIE complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202681_at AI346043 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI346043 /FEA=EST /DB_XREF=gi:4083249 /DB_XREF=est:qp48c09.x1 /CLONE=IMAGE:1926256 /UG=Hs.77500 ubiquitin specific protease 4 (proto-oncogene) /FL=gb:U20657.1 gb:AF017305.1 gb:NM_003363.1 AI346043 chromosome 3 open reading frame 62 /// microRNA 4271 /// ubiquitin specific peptidase 4 (proto-oncogene) C3orf62 /// MIR4271 /// USP4 7375 /// 375341 /// 100422952 NM_001251877 /// NM_003363 /// NM_198562 /// NM_199443 /// NR_036233 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031685 // adenosine receptor binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202682_s_at NM_003363 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003363.1 /DEF=Homo sapiens ubiquitin specific protease 4 (proto-oncogene) (USP4), mRNA. /FEA=mRNA /GEN=USP4 /PROD=ubiquitin specific protease, proto-oncogene /DB_XREF=gi:4507852 /UG=Hs.77500 ubiquitin specific protease 4 (proto-oncogene) /FL=gb:U20657.1 gb:AF017305.1 gb:NM_003363.1" NM_003363 ubiquitin specific peptidase 4 (proto-oncogene) USP4 7375 NM_001251877 /// NM_003363 /// NM_199443 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from direct assay /// 0034394 // protein localization to cell surface // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031685 // adenosine receptor binding // inferred from physical interaction /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202683_s_at NM_003799 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003799.1 /DEF=Homo sapiens RNA (guanine-7-) methyltransferase (RNMT), mRNA. /FEA=mRNA /GEN=RNMT /PROD=RNA (guanine-7-) methyltransferase /DB_XREF=gi:4506566 /UG=Hs.8086 RNA (guanine-7-) methyltransferase /FL=gb:AB007858.1 gb:AF067791.1 gb:AB022604.1 gb:NM_003799.1 gb:AB020966.1" NM_003799 RNA (guanine-7-) methyltransferase RNMT 8731 NM_003799 /// XM_005258160 /// XM_005258162 /// XM_006722361 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from mutant phenotype /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from direct assay /// 0036265 // RNA (guanine-N7)-methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from mutant phenotype /// 0036265 // RNA (guanine-N7)-methylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0003723 // RNA binding // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from direct assay /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202684_s_at AB020966 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB020966.1 /DEF=Homo sapiens hMet mRNA for RNA (guanine-N7-) methyltransferase, complete cds. /FEA=mRNA /GEN=hMet /PROD=RNA (guanine-N7-) methyltransferase /DB_XREF=gi:5478274 /UG=Hs.8086 RNA (guanine-7-) methyltransferase /FL=gb:AB007858.1 gb:AF067791.1 gb:AB022604.1 gb:NM_003799.1 gb:AB020966.1" AB020966 RNA (guanine-7-) methyltransferase RNMT 8731 NM_003799 /// XM_005258160 /// XM_005258162 /// XM_006722361 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from mutant phenotype /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from direct assay /// 0036265 // RNA (guanine-N7)-methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from mutant phenotype /// 0036265 // RNA (guanine-N7)-methylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005845 // mRNA cap binding complex // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay 0003723 // RNA binding // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from direct assay /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // inferred from mutant phenotype /// 0004482 // mRNA (guanine-N7-)-methyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202685_s_at AI467916 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI467916 /FEA=EST /DB_XREF=gi:4330006 /DB_XREF=est:tj84a10.x1 /CLONE=IMAGE:2148186 /UG=Hs.83341 AXL receptor tyrosine kinase /FL=gb:NM_021913.1 AI467916 AXL receptor tyrosine kinase AXL 558 NM_001278599 /// NM_001699 /// NM_021913 0001764 // neuron migration // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0021885 // forebrain cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0032940 // secretion by cell // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0048469 // cell maturation // inferred from expression pattern /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032036 // myosin heavy chain binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation" 202686_s_at NM_021913 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021913.1 /DEF=Homo sapiens AXL receptor tyrosine kinase (AXL), transcript variant 1, mRNA. /FEA=mRNA /GEN=AXL /PROD=AXL receptor tyrosine kinase isoform 1precursor /DB_XREF=gi:11863122 /UG=Hs.83341 AXL receptor tyrosine kinase /FL=gb:NM_021913.1" NM_021913 AXL receptor tyrosine kinase AXL 558 NM_001278599 /// NM_001699 /// NM_021913 0001764 // neuron migration // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0001961 // positive regulation of cytokine-mediated signaling pathway // inferred from direct assay /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0021885 // forebrain cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from direct assay /// 0032940 // secretion by cell // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0042698 // ovulation cycle // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0048469 // cell maturation // inferred from expression pattern /// 0051250 // negative regulation of lymphocyte activation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060068 // vagina development // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0097028 // dendritic cell differentiation // inferred from expression pattern /// 2000669 // negative regulation of dendritic cell apoptotic process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032036 // myosin heavy chain binding // inferred from electronic annotation /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation" 202687_s_at U57059 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U57059.1 /DEF=Homo sapiens Apo-2 ligand mRNA, complete cds. /FEA=mRNA /PROD=Apo-2 ligand /DB_XREF=gi:1336207 /UG=Hs.83429 tumor necrosis factor (ligand) superfamily, member 10 /FL=gb:U37518.1 gb:U57059.1 gb:NM_003810.1" U57059 "tumor necrosis factor (ligand) superfamily, member 10" TNFSF10 8743 NM_001190942 /// NM_001190943 /// NM_003810 /// NR_033994 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202688_at NM_003810 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003810.1 /DEF=Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), mRNA. /FEA=mRNA /GEN=TNFSF10 /PROD=tumor necrosis factor (ligand) superfamily,member 10 /DB_XREF=gi:4507592 /UG=Hs.83429 tumor necrosis factor (ligand) superfamily, member 10 /FL=gb:U37518.1 gb:U57059.1 gb:NM_003810.1" NM_003810 "tumor necrosis factor (ligand) superfamily, member 10" TNFSF10 8743 NM_001190942 /// NM_001190943 /// NM_003810 /// NR_033994 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001239 // regulation of extrinsic apoptotic signaling pathway in absence of ligand // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032813 // tumor necrosis factor receptor superfamily binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202689_at NM_013286 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013286.1 /DEF=Homo sapiens chromosome 3p21.1 gene sequence (HUMAGCGB), mRNA. /FEA=mRNA /GEN=HUMAGCGB /PROD=chromosome 3p21.1 gene sequence /DB_XREF=gi:7110644 /UG=Hs.84162 chromosome 3p21.1 gene sequence /FL=gb:BC001367.1 gb:L13434.1 gb:NM_013286.1" NM_013286 RNA binding motif protein 15B RBM15B 29890 NM_013286 "0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202690_s_at BC001721 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001721.1 /DEF=Homo sapiens, small nuclear ribonucleoprotein D1 polypeptide (16kD), clone MGC:2222, mRNA, complete cds. /FEA=mRNA /PROD=small nuclear ribonucleoprotein D1 polypeptide(16kD) /DB_XREF=gi:12804598 /UG=Hs.86948 small nuclear ribonucleoprotein D1 polypeptide (16kD) /FL=gb:BC001721.1 gb:J03798.1 gb:NM_006938.1" BC001721 small nuclear ribonucleoprotein D1 polypeptide 16kDa SNRPD1 6632 NM_001291916 /// NM_006938 "0000245 // spliceosomal complex assembly // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202691_at NM_006938 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006938.1 /DEF=Homo sapiens small nuclear ribonucleoprotein D1 polypeptide (16kD) (SNRPD1), mRNA. /FEA=mRNA /GEN=SNRPD1 /PROD=small nuclear ribonucleoprotein D1 polypeptide(16kD) /DB_XREF=gi:5902101 /UG=Hs.86948 small nuclear ribonucleoprotein D1 polypeptide (16kD) /FL=gb:BC001721.1 gb:J03798.1 gb:NM_006938.1" NM_006938 small nuclear ribonucleoprotein D1 polypeptide 16kDa SNRPD1 6632 NM_001291916 /// NM_006938 "0000245 // spliceosomal complex assembly // traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202692_s_at NM_014233 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014233.1 /DEF=Homo sapiens upstream binding transcription factor, RNA polymerase I (UBTF), mRNA. /FEA=mRNA /GEN=UBTF /PROD=upstream binding transcription factor, RNApolymerase I /DB_XREF=gi:7657670 /UG=Hs.89781 upstream binding transcription factor, RNA polymerase I /FL=gb:NM_014233.1" NM_014233 "upstream binding transcription factor, RNA polymerase I" UBTF 7343 NM_001076683 /// NM_001076684 /// NM_014233 /// NR_045058 /// XM_006722059 /// XM_006722060 /// XM_006722061 "0000183 // chromatin silencing at rDNA // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0045943 // positive regulation of transcription from RNA polymerase I promoter // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202693_s_at AW194730 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW194730 /FEA=EST /DB_XREF=gi:6473630 /DB_XREF=est:xn43d11.x1 /CLONE=IMAGE:2696469 /UG=Hs.9075 serinethreonine kinase 17a (apoptosis-inducing) /FL=gb:AB011420.1 gb:NM_004760.1 AW194730 serine/threonine kinase 17a STK17A 9263 NM_004760 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202694_at AW183478 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW183478 /FEA=EST /DB_XREF=gi:6451992 /DB_XREF=est:xj77a08.x1 /CLONE=IMAGE:2663222 /UG=Hs.9075 serinethreonine kinase 17a (apoptosis-inducing) /FL=gb:AB011420.1 gb:NM_004760.1 AW183478 serine/threonine kinase 17a STK17A 9263 NM_004760 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202695_s_at NM_004760 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004760.1 /DEF=Homo sapiens serinethreonine kinase 17a (apoptosis-inducing) (STK17A), mRNA. /FEA=mRNA /GEN=STK17A /PROD=serinethreonine kinase 17a(apoptosis-inducing) /DB_XREF=gi:4758191 /UG=Hs.9075 serinethreonine kinase 17a (apoptosis-inducing) /FL=gb:AB011420.1 gb:NM_004760.1" NM_004760 serine/threonine kinase 17a STK17A 9263 NM_004760 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 2000271 // positive regulation of fibroblast apoptotic process // inferred from mutant phenotype /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202696_at NM_005109 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005109.1 /DEF=Homo sapiens oxidative-stress responsive 1 (OSR1), mRNA. /FEA=mRNA /GEN=OSR1 /PROD=oxidative-stress responsive 1 /DB_XREF=gi:4826877 /UG=Hs.95220 oxidative-stress responsive 1 /FL=gb:AB017642.1 gb:NM_005109.1 gb:AB029024.1" NM_005109 oxidative stress responsive 1 OXSR1 9943 NM_005109 /// XM_005265638 0006468 // protein phosphorylation // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // not recorded /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay 0005737 // cytoplasm // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 202697_at NM_007006 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007006.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 5, 25 kD subunit (CPSF5), mRNA. /FEA=mRNA /GEN=CPSF5 /PROD=cleavage and polyadenylation specific factor 5,25 kD subunit /DB_XREF=gi:5901925 /UG=Hs.9605 cleavage and polyadenylation specific factor 5, 25 kD subunit /FL=gb:BC001403.1 gb:NM_007006.1" NM_007006 nudix (nucleoside diphosphate linked moiety X)-type motif 21 NUDT21 11051 NM_007006 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from direct assay /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from direct assay /// 0042382 // paraspeckles // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202698_x_at NM_001861 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001861.1 /DEF=Homo sapiens cytochrome c oxidase subunit IV (COX4), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX4 /PROD=cytochrome c oxidase subunit IV /DB_XREF=gi:4502980 /UG=Hs.113205 cytochrome c oxidase subunit IV /FL=gb:M21575.1 gb:M34600.1 gb:U90915.1 gb:NM_001861.1" NM_001861 cytochrome c oxidase subunit IV isoform 1 COX4I1 1327 NM_001861 /// XM_005255798 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202699_s_at AW510783 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW510783 /FEA=EST /DB_XREF=gi:7148861 /DB_XREF=est:hd39g03.x1 /CLONE=IMAGE:2911924 /UG=Hs.119387 KIAA0792 gene product /FL=gb:AB018335.1 gb:NM_014698.1 AW510783 transmembrane protein 63A TMEM63A 9725 NM_014698 /// XM_006711841 /// XM_006711842 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation 202700_s_at NM_014698 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014698.1 /DEF=Homo sapiens KIAA0792 gene product (KIAA0792), mRNA. /FEA=mRNA /GEN=KIAA0792 /PROD=KIAA0792 gene product /DB_XREF=gi:7662307 /UG=Hs.119387 KIAA0792 gene product /FL=gb:AB018335.1 gb:NM_014698.1" NM_014698 transmembrane protein 63A TMEM63A 9725 NM_014698 /// XM_006711841 /// XM_006711842 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation 202701_at NM_006129 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006129.2 /DEF=Homo sapiens bone morphogenetic protein 1 (BMP1), transcript variant BMP1-3, mRNA. /FEA=mRNA /GEN=BMP1 /PROD=bone morphogenetic protein 1, isoform 3,precursor /DB_XREF=gi:5902809 /UG=Hs.1274 bone morphogenetic protein 1 /FL=gb:U50330.1 gb:NM_006129.2" NM_006129 bone morphogenetic protein 1 BMP1 649 NM_001199 /// NM_006128 /// NM_006129 /// NM_006130 /// NM_006131 /// NM_006132 /// NR_033403 /// NR_033404 /// XM_006716386 /// XR_428315 0001501 // skeletal system development // non-traceable author statement /// 0001502 // cartilage condensation // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0007275 // multicellular organismal development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation 0004222 // metalloendopeptidase activity // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008237 // metallopeptidase activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202702_at NM_003449 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003449.1 /DEF=Homo sapiens zinc finger protein 173 (ZNF173), mRNA. /FEA=mRNA /GEN=ZNF173 /PROD=zinc finger protein 173 /DB_XREF=gi:4508004 /UG=Hs.1287 zinc finger protein 173 /FL=gb:NM_003449.1 gb:U09825.1" NM_003449 tripartite motif containing 26 TRIM26 7726 NM_001242783 /// NM_003449 /// XM_005249374 /// XM_005249375 /// XM_005249376 /// XM_005249377 /// XM_005249378 /// XM_005272870 /// XM_005272871 /// XM_005272872 /// XM_005274887 /// XM_005274888 /// XM_005274890 /// XM_005274891 /// XM_005275022 /// XM_005275023 /// XM_005275025 /// XM_005275026 /// XM_005275159 /// XM_005275160 /// XM_005275161 /// XM_005275452 /// XM_005275453 /// XM_005275455 /// XM_005275456 /// XM_005275590 /// XM_005275591 /// XM_005275592 /// XM_005275593 /// XM_005275594 /// XM_006715180 /// XM_006725500 0045087 // innate immune response // inferred from direct assay /// 0046597 // negative regulation of viral entry into host cell // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // non-traceable author statement 202703_at NM_003584 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003584.1 /DEF=Homo sapiens dual specificity phosphatase 11 (RNARNP complex 1-interacting) (DUSP11), mRNA. /FEA=mRNA /GEN=DUSP11 /PROD=dual specificity phosphatase 11 /DB_XREF=gi:4503414 /UG=Hs.14611 dual specificity phosphatase 11 (RNARNP complex 1-interacting) /FL=gb:BC000346.1 gb:AF023917.1 gb:NM_003584.1" NM_003584 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) DUSP11 8446 NM_003584 /// XM_005264604 /// XR_244962 0006396 // RNA processing // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016070 // RNA metabolic process // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0098507 // polynucleotide 5' dephosphorylation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation "0003723 // RNA binding // traceable author statement /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0098519 // nucleotide phosphatase activity, acting on free nucleotides // inferred from mutant phenotype" 202704_at AA675892 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA675892 /FEA=EST /DB_XREF=gi:2775239 /DB_XREF=est:b03503s /CLONE=b03503 /UG=Hs.178137 transducer of ERBB2, 1 /FL=gb:D38305.1 gb:NM_005749.1" AA675892 "transducer of ERBB2, 1" TOB1 10140 NM_001243877 /// NM_001243885 /// NM_005749 "0007184 // SMAD protein import into nucleus // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0060212 // negative regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030014 // CCR4-NOT complex // inferred from direct assay 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation 202705_at NM_004701 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004701.2 /DEF=Homo sapiens cyclin B2 (CCNB2), mRNA. /FEA=mRNA /GEN=CCNB2 /PROD=cyclin B2 /DB_XREF=gi:10938017 /UG=Hs.194698 cyclin B2 /FL=gb:NM_004701.2 gb:AF002822.1 gb:AB020981.1 gb:AL080146.1" NM_004701 cyclin B2 CCNB2 9133 NM_004701 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 202706_s_at D86227 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D86227.1 /DEF=Homo sapiens clone TA-UMPSpoly mRNA for UMP synthase, complete cds. /FEA=mRNA /GEN=UMPS /PROD=UMP synthase /DB_XREF=gi:2081619 /UG=Hs.2057 uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase) /FL=gb:BC000364.1 gb:D86227.1 gb:D86228.1 gb:D86230.1 gb:J03626.1 gb:NM_000373.1" D86227 uridine monophosphate synthetase UMPS 7372 NM_000373 /// NR_033434 /// NR_033437 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement "0003824 // catalytic activity // inferred from electronic annotation /// 0004588 // orotate phosphoribosyltransferase activity // inferred from direct assay /// 0004588 // orotate phosphoribosyltransferase activity // traceable author statement /// 0004590 // orotidine-5'-phosphate decarboxylase activity // inferred from direct assay /// 0004590 // orotidine-5'-phosphate decarboxylase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation" 202707_at NM_000373 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000373.1 /DEF=Homo sapiens uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase) (UMPS), mRNA. /FEA=mRNA /GEN=UMPS /PROD=uridine monophosphate synthetase (orotatephosphoribosyl transferase andorotidine-5-decarboxylase) /DB_XREF=gi:4507834 /UG=Hs.2057 uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase) /FL=gb:BC000364.1 gb:D86227.1 gb:D86228.1 gb:D86230.1 gb:J03626.1 gb:NM_000373.1" NM_000373 uridine monophosphate synthetase UMPS 7372 NM_000373 /// NR_033434 /// NR_033437 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement "0003824 // catalytic activity // inferred from electronic annotation /// 0004588 // orotate phosphoribosyltransferase activity // inferred from direct assay /// 0004588 // orotate phosphoribosyltransferase activity // traceable author statement /// 0004590 // orotidine-5'-phosphate decarboxylase activity // inferred from direct assay /// 0004590 // orotidine-5'-phosphate decarboxylase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation" 202708_s_at NM_003528 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003528.1 /DEF=Homo sapiens H2B histone family, member Q (H2BFQ), mRNA. /FEA=mRNA /GEN=H2BFQ /PROD=H2B histone family, member Q /DB_XREF=gi:4504276 /UG=Hs.2178 H2B histone family, member Q /FL=gb:NM_003528.1" NM_003528 "histone cluster 2, H2be" HIST2H2BE 8349 NM_003528 0002227 // innate immune response in mucosa // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006334 // nucleosome assembly // non-traceable author statement /// 0019731 // antibacterial humoral response // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay 0000786 // nucleosome // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 202709_at NM_002023 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002023.2 /DEF=Homo sapiens fibromodulin (FMOD), mRNA. /FEA=mRNA /GEN=FMOD /PROD=fibromodulin precursor /DB_XREF=gi:5016093 /UG=Hs.230 fibromodulin /FL=gb:NM_002023.2" NM_002023 fibromodulin FMOD 2331 NM_002023 /// NR_103757 0005975 // carbohydrate metabolic process // traceable author statement /// 0007181 // transforming growth factor beta receptor complex assembly // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement 0005515 // protein binding // inferred from electronic annotation 202710_at BC000899 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000899.1 /DEF=Homo sapiens, Golgi vesicular membrane trafficking protein p18, clone MGC:5210, mRNA, complete cds. /FEA=mRNA /PROD=Golgi vesicular membrane trafficking proteinp18 /DB_XREF=gi:12654162 /UG=Hs.23103 Bet1 (S. cerevisiae) homolog /FL=gb:BC000899.1 gb:NM_005868.2 gb:AF007551.1" BC000899 Bet1 golgi vesicular membrane trafficking protein BET1 10282 NM_005868 /// XM_005250109 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation 202711_at NM_004429 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004429.1 /DEF=Homo sapiens ephrin-B1 (EFNB1), mRNA. /FEA=mRNA /GEN=EFNB1 /PROD=ephrin-B1 /DB_XREF=gi:4758247 /UG=Hs.144700 ephrin-B1 /FL=gb:U09303.1 gb:NM_004429.1 gb:U09304.1 gb:L37361.1" NM_004429 ephrin-B1 EFNB1 1947 NM_004429 0001755 // neural crest cell migration // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0046875 // ephrin receptor binding // not recorded 202712_s_at NM_020990 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020990.2 /DEF=Homo sapiens creatine kinase, mitochondrial 1 (ubiquitous) (CKMT1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CKMT1 /PROD=ubiquitous mitochondrial creatine kinaseprecursor /DB_XREF=gi:11641403 /UG=Hs.153998 creatine kinase, mitochondrial 1 (ubiquitous) /FL=gb:NM_020990.2 gb:BC001926.1" NM_020990 "creatine kinase, mitochondrial 1A /// creatine kinase, mitochondrial 1B" CKMT1A /// CKMT1B 1159 /// 548596 NM_001015001 /// NM_020990 /// XM_005254150 /// XM_005254498 0006600 // creatine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004111 // creatine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202713_s_at AA129755 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA129755 /FEA=EST /DB_XREF=gi:1690165 /DB_XREF=est:zl16b10.s1 /CLONE=IMAGE:502075 /UG=Hs.154668 KIAA0391 gene product /FL=gb:AB002389.1 gb:NM_014672.1 AA129755 "KIAA0391 /// proteasome (prosome, macropain) subunit, alpha type, 6" KIAA0391 /// PSMA6 5687 /// 9692 NM_001256678 /// NM_001256679 /// NM_001256680 /// NM_001256681 /// NM_001282232 /// NM_001282233 /// NM_001282234 /// NM_002791 /// NM_014672 /// NR_104110 /// XM_005268237 /// XM_006720334 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050727 // regulation of inflammatory response // inferred by curator /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from mutant phenotype" "0000502 // proteasome complex // inferred from electronic annotation /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0005839 // proteasome core complex // non-traceable author statement /// 0005844 // polysome // inferred from direct assay /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from direct assay /// 0019773 // proteasome core complex, alpha-subunit complex // traceable author statement /// 0030016 // myofibril // inferred from sequence or structural similarity /// 0030017 // sarcomere // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0004175 // endopeptidase activity // non-traceable author statement /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035639 // purine ribonucleoside triphosphate binding // non-traceable author statement /// 0051059 // NF-kappaB binding // inferred from physical interaction 202714_s_at NM_014672 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014672.1 /DEF=Homo sapiens KIAA0391 gene product (KIAA0391), mRNA. /FEA=mRNA /GEN=KIAA0391 /PROD=KIAA0391 gene product /DB_XREF=gi:7662093 /UG=Hs.154668 KIAA0391 gene product /FL=gb:AB002389.1 gb:NM_014672.1" NM_014672 KIAA0391 KIAA0391 9692 NM_001256678 /// NM_001256679 /// NM_001256680 /// NM_001256681 /// NM_014672 /// XM_005268237 /// XM_006720334 0008033 // tRNA processing // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 202715_at NM_004341 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004341.1 /DEF=Homo sapiens carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CAD /PROD=carbamoyl-phosphate synthetase 2, aspartatetranscarbamylase, and dihydroorotase /DB_XREF=gi:4757895 /UG=Hs.154868 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase /FL=gb:D78586.1 gb:NM_004341.1" NM_004341 "carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" CAD 790 NM_004341 /// XM_005264555 /// XM_005264556 /// XM_005264557 /// XM_005264558 /// XM_006712101 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from direct assay /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from sequence or structural similarity /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006543 // glutamine catabolic process // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0017144 // drug metabolic process // inferred from sequence or structural similarity /// 0018107 // peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0031000 // response to caffeine // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0051414 // response to cortisol // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0070409 // carbamoyl phosphate biosynthetic process // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0042995 // cell projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043195 // terminal bouton // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004070 // aspartate carbamoyltransferase activity // inferred from sequence or structural similarity /// 0004070 // aspartate carbamoyltransferase activity // traceable author statement /// 0004088 // carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity // inferred from sequence or structural similarity /// 0004088 // carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity // traceable author statement /// 0004151 // dihydroorotase activity // inferred from direct assay /// 0004151 // dihydroorotase activity // inferred from sequence or structural similarity /// 0004151 // dihydroorotase activity // traceable author statement /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016743 // carboxyl- or carbamoyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016812 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070335 // aspartate binding // inferred from sequence or structural similarity" 202716_at NM_002827 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002827.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 1 (PTPN1), mRNA. /FEA=mRNA /GEN=PTPN1 /PROD=protein tyrosine phosphatase, non-receptor type1 /DB_XREF=gi:4506288 /UG=Hs.155894 protein tyrosine phosphatase, non-receptor type 1 /FL=gb:M33689.1 gb:M31724.1 gb:NM_002827.1" NM_002827 "protein tyrosine phosphatase, non-receptor type 1" PTPN1 5770 NM_001278618 /// NM_002827 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030100 // regulation of endocytosis // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from mutant phenotype /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0035791 // platelet-derived growth factor receptor-beta signaling pathway // inferred from mutant phenotype /// 0046626 // regulation of insulin receptor signaling pathway // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // non-traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1990264 // peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity // inferred from sequence or structural similarity 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0097443 // sorting endosome // inferred from sequence or structural similarity 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046875 // ephrin receptor binding // inferred from physical interaction 202717_s_at NM_003903 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003903.1 /DEF=Homo sapiens CDC16 (cell division cycle 16, S. cerevisiae, homolog) (CDC16), mRNA. /FEA=mRNA /GEN=CDC16 /PROD=CDC16 (cell division cycle 16, S. cerevisiae,homolog) /DB_XREF=gi:4502700 /UG=Hs.1592 CDC16 (cell division cycle 16, S. cerevisiae, homolog) /FL=gb:NM_003903.1 gb:U18291.1" NM_003903 cell division cycle 16 CDC16 8881 NM_001078645 /// NM_003903 /// XM_005266204 /// XM_005266206 /// XM_006719992 /// XM_006719993 /// XR_245358 /// XR_245359 /// XR_245360 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202718_at NM_000597 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000597.1 /DEF=Homo sapiens insulin-like growth factor binding protein 2 (36kD) (IGFBP2), mRNA. /FEA=mRNA /GEN=IGFBP2 /PROD=insulin-like growth factor binding protein 2(36kD) /DB_XREF=gi:10835156 /UG=Hs.162 insulin-like growth factor binding protein 2 (36kD) /FL=gb:NM_000597.1 gb:BC004312.1 gb:M35410.1" NM_000597 "insulin-like growth factor binding protein 2, 36kDa" IGFBP2 3485 NM_000597 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred by curator /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from direct assay /// 0031995 // insulin-like growth factor II binding // inferred from sequence or structural similarity 202719_s_at BC001451 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001451.1 /DEF=Homo sapiens, testin, clone MGC:1146, mRNA, complete cds. /FEA=mRNA /PROD=testin /DB_XREF=gi:12655188 /UG=Hs.165986 testin /FL=gb:AF245356.1 gb:AF245357.1 gb:BC001451.1 gb:NM_015641.1" BC001451 testis derived transcript (3 LIM domains) TES 26136 NM_015641 /// NM_152829 /// XM_005250258 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0008270 // zinc ion binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202720_at NM_015641 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015641.1 /DEF=Homo sapiens testin (DKFZP586B2022), mRNA. /FEA=mRNA /GEN=DKFZP586B2022 /PROD=testin /DB_XREF=gi:7661665 /UG=Hs.165986 testin /FL=gb:AF245356.1 gb:AF245357.1 gb:BC001451.1 gb:NM_015641.1" NM_015641 testis derived transcript (3 LIM domains) TES 26136 NM_015641 /// NM_152829 /// XM_005250258 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0008270 // zinc ion binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202721_s_at BE645771 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE645771 /FEA=EST /DB_XREF=gi:9970082 /DB_XREF=est:7e76b02.x1 /CLONE=IMAGE:3288363 /UG=Hs.1674 glutamine-fructose-6-phosphate transaminase 1 /FL=gb:M90516.1 gb:NM_002056.1 BE645771 glutamine--fructose-6-phosphate transaminase 1 GFPT1 2673 NM_001244710 /// NM_002056 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006042 // glucosamine biosynthetic process // inferred from electronic annotation /// 0006047 // UDP-N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004360 // glutamine-fructose-6-phosphate transaminase (isomerizing) activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 202722_s_at NM_002056 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002056.1 /DEF=Homo sapiens glutamine-fructose-6-phosphate transaminase 1 (GFPT1), mRNA. /FEA=mRNA /GEN=GFPT1 /PROD=glucosamine-fructose-6-phosphateaminotransferase /DB_XREF=gi:4503980 /UG=Hs.1674 glutamine-fructose-6-phosphate transaminase 1 /FL=gb:M90516.1 gb:NM_002056.1" NM_002056 glutamine--fructose-6-phosphate transaminase 1 GFPT1 2673 NM_001244710 /// NM_002056 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006002 // fructose 6-phosphate metabolic process // inferred from electronic annotation /// 0006042 // glucosamine biosynthetic process // inferred from electronic annotation /// 0006047 // UDP-N-acetylglucosamine metabolic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // inferred from electronic annotation /// 0006048 // UDP-N-acetylglucosamine biosynthetic process // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004360 // glutamine-fructose-6-phosphate transaminase (isomerizing) activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 202723_s_at AW117498 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW117498 /FEA=EST /DB_XREF=gi:6086082 /DB_XREF=est:xd92e10.x1 /CLONE=IMAGE:2605098 /UG=Hs.170133 forkhead box O1A (rhabdomyosarcoma) /FL=gb:AF032885.1 gb:U02310.1 gb:NM_002015.2 AW117498 forkhead box O1 FOXO1 2308 NM_002015 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // not recorded /// 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001678 // cellular glucose homeostasis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070417 // cellular response to cold // inferred from sequence or structural similarity /// 0071455 // cellular response to hyperoxia // inferred from direct assay /// 0071732 // cellular response to nitric oxide // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement "0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity" 202724_s_at NM_002015 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002015.2 /DEF=Homo sapiens forkhead box O1A (rhabdomyosarcoma) (FOXO1A), mRNA. /FEA=mRNA /GEN=FOXO1A /PROD=forkhead box O1A /DB_XREF=gi:9257221 /UG=Hs.170133 forkhead box O1A (rhabdomyosarcoma) /FL=gb:AF032885.1 gb:U02310.1 gb:NM_002015.2" NM_002015 forkhead box O1 FOXO1 2308 NM_002015 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // not recorded /// 0001659 // temperature homeostasis // inferred from sequence or structural similarity /// 0001678 // cellular glucose homeostasis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006473 // protein acetylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009267 // cellular response to starvation // inferred from direct assay /// 0009267 // cellular response to starvation // inferred from sequence or structural similarity /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0031018 // endocrine pancreas development // traceable author statement /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0032873 // negative regulation of stress-activated MAPK cascade // inferred from direct assay /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045599 // negative regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0070417 // cellular response to cold // inferred from sequence or structural similarity /// 0071455 // cellular response to hyperoxia // inferred from direct assay /// 0071732 // cellular response to nitric oxide // inferred from sequence or structural similarity /// 2000505 // regulation of energy homeostasis // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement "0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0051721 // protein phosphatase 2A binding // inferred from sequence or structural similarity" 202725_at NM_000937 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000937.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide A (220kD) (POLR2A), mRNA. /FEA=mRNA /GEN=POLR2A /PROD=polymerase (RNA) II (DNA directed) polypeptide A(220kD) /DB_XREF=gi:4505938 /UG=Hs.171880 polymerase (RNA) II (DNA directed) polypeptide A (220kD) /FL=gb:NM_000937.1" NM_000937 "polymerase (RNA) II (DNA directed) polypeptide A, 220kDa" POLR2A 5430 NM_000937 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0001172 // transcription, RNA-templated // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" "0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay" 0001055 // RNA polymerase II activity // not recorded /// 0003677 // DNA binding // non-traceable author statement /// 0003899 // DNA-directed RNA polymerase activity // non-traceable author statement /// 0003968 // RNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202726_at NM_000234 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000234.1 /DEF=Homo sapiens ligase I, DNA, ATP-dependent (LIG1), mRNA. /FEA=mRNA /GEN=LIG1 /PROD=DNA ligase I /DB_XREF=gi:4557718 /UG=Hs.1770 ligase I, DNA, ATP-dependent /FL=gb:M36067.1 gb:NM_000234.1" NM_000234 "ligase I, DNA, ATP-dependent" LIG1 3978 NM_000234 /// NM_001289063 /// NM_001289064 /// NR_110296 /// XM_005258934 /// XM_006723215 /// XM_006723216 /// XM_006723217 /// XR_243932 /// XR_243934 /// XR_430200 /// XR_430201 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006273 // lagging strand elongation // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // not recorded /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0033151 // V(D)J recombination // inferred from direct assay /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" 0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // not recorded /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003909 // DNA ligase activity // inferred from direct assay /// 0003910 // DNA ligase (ATP) activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202727_s_at NM_000416 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000416.1 /DEF=Homo sapiens interferon gamma receptor 1 (IFNGR1), mRNA. /FEA=mRNA /GEN=IFNGR1 /PROD=interferon gamma receptor 1 /DB_XREF=gi:4557879 /UG=Hs.180866 interferon gamma receptor 1 /FL=gb:BC005333.1 gb:J03143.1 gb:NM_000416.1" NM_000416 interferon gamma receptor 1 IFNGR1 3459 NM_000416 /// XM_006715470 /// XM_006715471 0007165 // signal transduction // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation 0004906 // interferon-gamma receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from electronic annotation 202728_s_at AI986120 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI986120 /FEA=EST /DB_XREF=gi:5813397 /DB_XREF=est:wr80e09.x1 /CLONE=IMAGE:2494024 /UG=Hs.241257 latent transforming growth factor beta binding protein 1 /FL=gb:M34057.1 gb:NM_000627.1 AI986120 latent transforming growth factor beta binding protein 1 LTBP1 4052 NM_000627 /// NM_001166264 /// NM_001166265 /// NM_001166266 /// NM_206943 /// XM_005264315 /// XM_005264316 /// XM_005264317 /// XM_005264318 /// XM_005264319 /// XM_006712019 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035583 // sequestering of TGFbeta in extracellular matrix // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 202729_s_at NM_000627 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000627.1 /DEF=Homo sapiens latent transforming growth factor beta binding protein 1 (LTBP1), mRNA. /FEA=mRNA /GEN=LTBP1 /PROD=latent transforming growth factor beta bindingprotein 1 precursor /DB_XREF=gi:4557730 /UG=Hs.241257 latent transforming growth factor beta binding protein 1 /FL=gb:M34057.1 gb:NM_000627.1" NM_000627 latent transforming growth factor beta binding protein 1 LTBP1 4052 NM_000627 /// NM_001166264 /// NM_001166265 /// NM_001166266 /// NM_206943 /// XM_005264315 /// XM_005264316 /// XM_005264317 /// XM_005264318 /// XM_005264319 /// XM_006712019 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035583 // sequestering of TGFbeta in extracellular matrix // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0005024 // transforming growth factor beta-activated receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 202730_s_at NM_014456 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014456.1 /DEF=Homo sapiens programmed cell death 4 (PDCD4), mRNA. /FEA=mRNA /GEN=PDCD4 /PROD=programmed cell death 4 /DB_XREF=gi:7657448 /UG=Hs.296251 programmed cell death 4 /FL=gb:U96628.1 gb:NM_014456.1" NM_014456 microRNA 4680 /// programmed cell death 4 (neoplastic transformation inhibitor) MIR4680 /// PDCD4 27250 /// 100616113 NM_001199492 /// NM_014456 /// NM_145341 /// NR_039828 /// XM_005269702 /// XM_006717767 "0006915 // apoptotic process // non-traceable author statement /// 0007569 // cell aging // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202731_at NM_014456 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014456.1 /DEF=Homo sapiens programmed cell death 4 (PDCD4), mRNA. /FEA=mRNA /GEN=PDCD4 /PROD=programmed cell death 4 /DB_XREF=gi:7657448 /UG=Hs.296251 programmed cell death 4 /FL=gb:U96628.1 gb:NM_014456.1" NM_014456 microRNA 4680 /// programmed cell death 4 (neoplastic transformation inhibitor) MIR4680 /// PDCD4 27250 /// 100616113 NM_001199492 /// NM_014456 /// NM_145341 /// NR_039828 /// XM_005269702 /// XM_006717767 "0006915 // apoptotic process // non-traceable author statement /// 0007569 // cell aging // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0043508 // negative regulation of JUN kinase activity // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202732_at NM_007066 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007066.1 /DEF=Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor gamma (PKIG), mRNA. /FEA=mRNA /GEN=PKIG /PROD=protein kinase (cAMP-dependent, catalytic)inhibitor gamma /DB_XREF=gi:5902019 /UG=Hs.3407 protein kinase (cAMP-dependent, catalytic) inhibitor gamma /FL=gb:AB019517.1 gb:AF182032.1 gb:NM_007066.1" NM_007066 "protein kinase (cAMP-dependent, catalytic) inhibitor gamma" PKIG 11142 NM_001281444 /// NM_001281445 /// NM_007066 /// NM_181804 /// NM_181805 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 202733_at NM_004199 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004199.1 /DEF=Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II (P4HA2), mRNA. /FEA=mRNA /GEN=P4HA2 /PROD=procollagen-proline, 2-oxoglutarate4-dioxygenase (proline 4-hydroxylase), alpha polypeptideII /DB_XREF=gi:4758867 /UG=Hs.3622 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II /FL=gb:U90441.1 gb:NM_004199.1" NM_004199 "uncharacterized LOC101927705 /// prolyl 4-hydroxylase, alpha polypeptide II" LOC101927705 /// P4HA2 8974 /// 101927705 NM_001017973 /// NM_001017974 /// NM_001142598 /// NM_001142599 /// NM_004199 /// XM_005272116 /// XM_005272117 /// XM_005272118 /// XM_005272119 /// XM_005272120 /// XM_005272122 /// XM_006714728 /// XM_006714729 /// XM_006714730 /// XM_006714731 /// XR_246585 /// XR_249830 /// XR_251870 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0004656 // procollagen-proline 4-dioxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation" 202734_at NM_004240 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004240.1 /DEF=Homo sapiens thyroid hormone receptor interactor 10 (TRIP10), mRNA. /FEA=mRNA /GEN=TRIP10 /PROD=thyroid hormone receptor interactor 10 /DB_XREF=gi:11342675 /UG=Hs.73999 thyroid hormone receptor interactor 10 /FL=gb:NM_004240.1" NM_004240 thyroid hormone receptor interactor 10 TRIP10 9322 NM_001288962 /// NM_001288963 /// NM_004240 /// NR_110231 /// XM_005259683 /// XM_006722940 /// XR_430161 0006897 // endocytosis // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001891 // phagocytic cup // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202735_at NM_006579 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006579.1 /DEF=Homo sapiens emopamil-binding protein (sterol isomerase) (EBP), mRNA. /FEA=mRNA /GEN=EBP /PROD=emopamil-binding protein (sterol isomerase) /DB_XREF=gi:5729809 /UG=Hs.75105 emopamil-binding protein (sterol isomerase) /FL=gb:NM_006579.1" NM_006579 emopamil binding protein (sterol isomerase) EBP 10682 NM_006579 0001501 // skeletal system development // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006855 // drug transmembrane transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0016125 // sterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004769 // steroid delta-isomerase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0015238 // drug transmembrane transporter activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0047750 // cholestenol delta-isomerase activity // inferred from electronic annotation 202736_s_at AA112507 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA112507 /FEA=EST /DB_XREF=gi:1665056 /DB_XREF=est:zm28c01.r1 /CLONE=IMAGE:526944 /UG=Hs.76719 U6 snRNA-associated Sm-like protein /FL=gb:BC000387.1 gb:BC003652.1 gb:AF182290.1 gb:AF117235.1 gb:NM_012321.1 gb:AF251218.1 AA112507 "LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)" LSM4 25804 NM_001252129 /// NM_012321 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005688 // U6 snRNP // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202737_s_at NM_012321 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012321.1 /DEF=Homo sapiens U6 snRNA-associated Sm-like protein (LSM4), mRNA. /FEA=mRNA /GEN=LSM4 /PROD=U6 snRNA-associated Sm-like protein /DB_XREF=gi:6912485 /UG=Hs.76719 U6 snRNA-associated Sm-like protein /FL=gb:BC000387.1 gb:BC003652.1 gb:AF182290.1 gb:AF117235.1 gb:NM_012321.1 gb:AF251218.1" NM_012321 "LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)" LSM4 25804 NM_001252129 /// NM_012321 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005688 // U6 snRNP // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 202738_s_at BG149218 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG149218 /FEA=EST /DB_XREF=gi:12661248 /DB_XREF=est:nad24g09.x1 /CLONE=IMAGE:3366712 /UG=Hs.78060 phosphorylase kinase, beta /FL=gb:NM_000293.1" BG149218 "phosphorylase kinase, beta" PHKB 5257 NM_000293 /// NM_001031835 /// XM_005255983 /// XM_005255984 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005964 // phosphorylase kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation" 202739_s_at NM_000293 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000293.1 /DEF=Homo sapiens phosphorylase kinase, beta (PHKB), mRNA. /FEA=mRNA /GEN=PHKB /PROD=phosphorylase kinase, beta /DB_XREF=gi:4505782 /UG=Hs.78060 phosphorylase kinase, beta /FL=gb:NM_000293.1" NM_000293 "phosphorylase kinase, beta" PHKB 5257 NM_000293 /// NM_001031835 /// XM_005255983 /// XM_005255984 0005975 // carbohydrate metabolic process // traceable author statement /// 0005976 // polysaccharide metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // traceable author statement /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005964 // phosphorylase kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004689 // phosphorylase kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation" 202740_at NM_000666 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000666.1 /DEF=Homo sapiens aminoacylase 1 (ACY1), mRNA. /FEA=mRNA /GEN=ACY1 /PROD=aminoacylase 1 /DB_XREF=gi:4501900 /UG=Hs.79 aminoacylase 1 /FL=gb:BC000545.1 gb:BC003023.1 gb:L07548.1 gb:D14524.1 gb:D16307.1 gb:NM_000666.1" NM_000666 ABHD14A-ACY1 readthrough (NMD candidate) /// aminoacylase 1 ABHD14A-ACY1 /// ACY1 95 /// 100526760 NM_000666 /// NM_001198895 /// NM_001198896 /// NM_001198897 /// NM_001198898 /// NR_037192 0006508 // proteolysis // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004046 // aminoacylase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202741_at AA130247 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA130247 /FEA=EST /DB_XREF=gi:1691251 /DB_XREF=est:zl38g12.s1 /CLONE=IMAGE:504262 /UG=Hs.87773 protein kinase, cAMP-dependent, catalytic, beta /FL=gb:M34181.1 gb:NM_002731.1" AA130247 "protein kinase, cAMP-dependent, catalytic, beta" PRKACB 5567 NM_001242857 /// NM_001242858 /// NM_001242859 /// NM_001242860 /// NM_001242861 /// NM_001242862 /// NM_002731 /// NM_182948 /// NM_207578 /// XM_005271015 /// XM_005271016 /// XM_005271017 /// XM_005271018 /// XM_005271019 /// XM_005271020 /// XM_005271021 /// XM_005271022 /// XM_005271023 /// XM_006710758 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051447 // negative regulation of meiotic cell cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0097338 // response to clozapine // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay" 202742_s_at NM_002731 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002731.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, catalytic, beta (PRKACB), mRNA. /FEA=mRNA /GEN=PRKACB /PROD=protein kinase, cAMP-dependent, catalytic, beta /DB_XREF=gi:4506056 /UG=Hs.87773 protein kinase, cAMP-dependent, catalytic, beta /FL=gb:M34181.1 gb:NM_002731.1" NM_002731 "protein kinase, cAMP-dependent, catalytic, beta" PRKACB 5567 NM_001242857 /// NM_001242858 /// NM_001242859 /// NM_001242860 /// NM_001242861 /// NM_001242862 /// NM_002731 /// NM_182948 /// NM_207578 /// XM_005271015 /// XM_005271016 /// XM_005271017 /// XM_005271018 /// XM_005271019 /// XM_005271020 /// XM_005271021 /// XM_005271022 /// XM_005271023 /// XM_006710758 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0051447 // negative regulation of meiotic cell cycle // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0097338 // response to clozapine // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay" 202743_at BE622627 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE622627 /FEA=EST /DB_XREF=gi:9893567 /DB_XREF=est:601440792T1 /CLONE=IMAGE:3915695 /UG=Hs.88051 phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma) /FL=gb:D88532.1 gb:NM_003629.1" BE622627 "phosphoinositide-3-kinase, regulatory subunit 3 (gamma)" PIK3R3 8503 NM_001114172 /// NM_003629 /// XM_005271290 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // traceable author statement /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation 202744_at NM_006749 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006749.1 /DEF=Homo sapiens solute carrier family 20 (phosphate transporter), member 2 (SLC20A2), mRNA. /FEA=mRNA /GEN=SLC20A2 /PROD=solute carrier family 20 (phosphatetransporter), member 2 /DB_XREF=gi:5803172 /UG=Hs.10018 solute carrier family 20 (phosphate transporter), member 2 /FL=gb:L20852.1 gb:NM_006749.1" NM_006749 "solute carrier family 20 (phosphate transporter), member 2" SLC20A2 6575 NM_001257180 /// NM_001257181 /// NM_006749 /// XM_005273613 /// XM_005273615 /// XM_006716390 /// XM_006716391 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 202745_at NM_005154 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005154.1 /DEF=Homo sapiens ubiquitin specific protease 8 (USP8), mRNA. /FEA=mRNA /GEN=USP8 /PROD=ubiquitin specific protease 8 /DB_XREF=gi:4827053 /UG=Hs.152818 ubiquitin specific protease 8 /FL=gb:D29956.1 gb:NM_005154.1" NM_005154 ubiquitin specific peptidase 8 USP8 9101 NM_001128610 /// NM_001128611 /// NM_001283049 /// NM_005154 /// XM_006720761 /// XM_006720762 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007032 // endosome organization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 202746_at AL021786 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL021786 /DEF=Human DNA sequence from PAC 696H22 on chromosome Xq21.1-21.2. Contains a mouse E25 like gene, a Kinesin like pseudogene and ESTs /FEA=mRNA /DB_XREF=gi:2853186 /UG=Hs.17109 integral membrane protein 2A /FL=gb:AF038953.1 gb:NM_004867.1" AL021786 integral membrane protein 2A ITM2A 9452 NM_001171581 /// NM_004867 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202747_s_at NM_004867 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004867.1 /DEF=Homo sapiens integral membrane protein 2A (ITM2A), mRNA. /FEA=mRNA /GEN=ITM2A /PROD=integral membrane protein 2A /DB_XREF=gi:4758223 /UG=Hs.17109 integral membrane protein 2A /FL=gb:AF038953.1 gb:NM_004867.1" NM_004867 integral membrane protein 2A ITM2A 9452 NM_001171581 /// NM_004867 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202748_at NM_004120 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004120.2 /DEF=Homo sapiens guanylate binding protein 2, interferon-inducible (GBP2), mRNA. /FEA=mRNA /GEN=GBP2 /PROD=guanylate binding protein 2,interferon-inducible /DB_XREF=gi:6996011 /UG=Hs.171862 guanylate binding protein 2, interferon-inducible /FL=gb:NM_004120.2 gb:M55543.1" NM_004120 "guanylate binding protein 2, interferon-inducible" GBP2 2634 NM_004120 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 202749_at NM_004627 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004627.1 /DEF=Homo sapiens tryptophan rich basic protein (WRB), mRNA. /FEA=mRNA /GEN=WRB /PROD=tryptophan rich basic protein /DB_XREF=gi:4759325 /UG=Hs.198308 tryptophan rich basic protein /FL=gb:NM_004627.1" NM_004627 tryptophan rich basic protein WRB 7485 NM_001146218 /// NM_004627 /// XM_005261059 /// XM_005261060 /// XM_005261061 0071816 // tail-anchored membrane protein insertion into ER membrane // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202750_s_at AL080147 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:AL080147.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434B194 (from clone DKFZp434B194); complete cds. /FEA=mRNA /GEN=DKFZp434B194 /PROD=hypothetical protein /DB_XREF=gi:5262598 /UG=Hs.20225 tuftelin-interacting protein /FL=gb:AL080147.1 gb:NM_012143.1 AL080147 tuftelin interacting protein 11 TFIP11 24144 NM_001008697 /// NM_012143 "0000390 // spliceosomal complex disassembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation" 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202751_at NM_012143 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012143.1 /DEF=Homo sapiens tuftelin-interacting protein (TIP39), mRNA. /FEA=mRNA /GEN=TIP39 /PROD=tuftelin-interacting protein /DB_XREF=gi:8393258 /UG=Hs.20225 tuftelin-interacting protein /FL=gb:AL080147.1 gb:NM_012143.1" NM_012143 tuftelin interacting protein 11 TFIP11 24144 NM_001008697 /// NM_012143 "0000390 // spliceosomal complex disassembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation" 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay /// 0071008 // U2-type post-mRNA release spliceosomal complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202752_x_at NM_012244 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012244.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (SLC7A8), mRNA. /FEA=mRNA /GEN=SLC7A8 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 8 /DB_XREF=gi:6912669 /UG=Hs.22891 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 /FL=gb:AB037669.1 gb:AF171669.1 gb:NM_012244.1" NM_012244 "solute carrier family 7 (amino acid transporter light chain, L system), member 8" SLC7A8 23428 NM_001267036 /// NM_001267037 /// NM_012244 /// NM_182728 /// NR_049767 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // inferred from direct assay /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0009636 // response to toxic substance // non-traceable author statement /// 0015695 // organic cation transport // inferred from direct assay /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055065 // metal ion homeostasis // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1901998 // toxin transport // inferred from direct assay /// 1902475 // L-alpha-amino acid transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015101 // organic cation transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // not recorded /// 0015171 // amino acid transmembrane transporter activity // inferred from direct assay /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0019534 // toxin transporter activity // inferred from direct assay /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 202753_at NM_014814 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014814.1 /DEF=Homo sapiens KIAA0107 gene product (KIAA0107), mRNA. /FEA=mRNA /GEN=KIAA0107 /PROD=KIAA0107 gene product /DB_XREF=gi:7661913 /UG=Hs.23488 KIAA0107 gene product /FL=gb:BC000630.1 gb:BC000904.2 gb:D14663.1 gb:AF215935.1 gb:NM_014814.1" NM_014814 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 6" PSMD6 9861 NM_001271779 /// NM_001271780 /// NM_001271781 /// NM_014814 /// XM_005265618 /// XM_005265619 /// XM_006713431 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006508 // proteolysis // non-traceable author statement /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0016887 // ATPase activity // non-traceable author statement 202754_at NM_015361 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015361.1 /DEF=Homo sapiens KIAA0029 protein (KIAA0029), mRNA. /FEA=mRNA /GEN=KIAA0029 /PROD=KIAA0029 protein /DB_XREF=gi:7661873 /UG=Hs.268053 KIAA0029 protein /FL=gb:NM_015361.1" NM_015361 R3H domain containing 1 R3HDM1 23518 NM_001282798 /// NM_001282799 /// NM_001282800 /// NM_015361 /// XM_005263622 /// XM_005263623 /// XM_005263624 /// XM_005263626 /// XM_005263627 /// XM_005263628 /// XM_005263629 /// XM_005263631 /// XM_005263632 /// XM_005263633 /// XM_006712389 /// XM_006712390 /// XM_006712391 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202755_s_at AI354864 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI354864 /FEA=EST /DB_XREF=gi:4095017 /DB_XREF=est:qt76c12.x1 /CLONE=IMAGE:1961206 /UG=Hs.2699 glypican 1 /FL=gb:NM_002081.1 AI354864 glypican 1 GPC1 2817 NM_002081 "0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0014037 // Schwann cell differentiation // inferred from sequence or structural similarity /// 0030200 // heparan sulfate proteoglycan catabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032288 // myelin assembly // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045121 // membrane raft // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // inferred from sequence or structural similarity /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 202756_s_at NM_002081 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002081.1 /DEF=Homo sapiens glypican 1 (GPC1), mRNA. /FEA=mRNA /GEN=GPC1 /PROD=glypican 1 precursor /DB_XREF=gi:4504080 /UG=Hs.2699 glypican 1 /FL=gb:NM_002081.1" NM_002081 glypican 1 GPC1 2817 NM_002081 "0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0014037 // Schwann cell differentiation // inferred from sequence or structural similarity /// 0030200 // heparan sulfate proteoglycan catabolic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0032288 // myelin assembly // inferred from sequence or structural similarity /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 2001016 // positive regulation of skeletal muscle cell differentiation // inferred from sequence or structural similarity" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045121 // membrane raft // inferred from direct assay /// 0045121 // membrane raft // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005507 // copper ion binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from sequence or structural similarity /// 0043236 // laminin binding // inferred from sequence or structural similarity /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation 202757_at NM_015456 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015456.1 /DEF=Homo sapiens DKFZP586B0519 protein (DKFZP586B0519), mRNA. /FEA=mRNA /GEN=DKFZP586B0519 /PROD=DKFZP586B0519 protein /DB_XREF=gi:7661663 /UG=Hs.27633 DKFZP586B0519 protein /FL=gb:AL050280.1 gb:NM_015456.1" NM_015456 negative elongation factor complex member B NELFB 25920 NM_015456 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032021 // NELF complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202758_s_at NM_003721 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003721.1 /DEF=Homo sapiens regulatory factor X-associated ankyrin-containing protein (RFXANK), mRNA. /FEA=mRNA /GEN=RFXANK /PROD=regulatory factor X-associatedankyrin-containing protein /DB_XREF=gi:4506498 /UG=Hs.296776 regulatory factor X-associated ankyrin-containing protein /FL=gb:AF094760.1 gb:AF105427.1 gb:NM_003721.1 gb:AF077196.1" NM_003721 regulatory factor X-associated ankyrin-containing protein RFXANK 8625 NM_001278727 /// NM_001278728 /// NM_003721 /// NM_134440 /// XM_005260134 /// XM_005260135 /// XM_005260136 /// XM_005260137 /// XM_006722930 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from electronic annotation 202759_s_at BE879367 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE879367 /FEA=EST /DB_XREF=gi:10328143 /DB_XREF=est:601484628F1 /CLONE=IMAGE:3887262 /UG=Hs.42322 A kinase (PRKA) anchor protein 2 /FL=gb:AB023137.1 gb:NM_007203.1 BE879367 A kinase (PRKA) anchor protein 2 /// PALM2-AKAP2 readthrough AKAP2 /// PALM2-AKAP2 11217 /// 445815 NM_001004065 /// NM_001136562 /// NM_001198656 /// NM_007203 /// NM_147150 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 202760_s_at NM_007203 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007203.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 2 (AKAP2), mRNA. /FEA=mRNA /GEN=AKAP2 /PROD=A kinase (PRKA) anchor protein 2 /DB_XREF=gi:6005708 /UG=Hs.42322 A kinase (PRKA) anchor protein 2 /FL=gb:AB023137.1 gb:NM_007203.1" NM_007203 A kinase (PRKA) anchor protein 2 /// PALM2-AKAP2 readthrough AKAP2 /// PALM2-AKAP2 11217 /// 445815 NM_001004065 /// NM_001136562 /// NM_001198656 /// NM_007203 /// NM_147150 0008360 // regulation of cell shape // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 202761_s_at NM_015180 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015180.1 /DEF=Homo sapiens synaptic nuclei expressed gene 2; KIAA1011 protein (KIAA1011), mRNA. /FEA=mRNA /GEN=KIAA1011 /PROD=KIAA1011 protein /DB_XREF=gi:11056019 /UG=Hs.57749 synaptic nuclei expressed gene 2; KIAA1011 protein /FL=gb:NM_015180.1 gb:AL080133.1" NM_015180 "spectrin repeat containing, nuclear envelope 2" SYNE2 23224 NM_015180 /// NM_182910 /// NM_182912 /// NM_182913 /// NM_182914 /// XM_005267454 /// XM_005267455 /// XM_005267456 /// XM_005267457 /// XM_005267458 /// XM_005267459 /// XM_005267460 /// XM_006720084 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007097 // nuclear migration // inferred from mutant phenotype /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0010761 // fibroblast migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031022 // nuclear migration along microfilament // inferred from sequence or structural similarity /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0051642 // centrosome localization // inferred from mutant phenotype /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030016 // myofibril // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0031981 // nuclear lumen // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202762_at AL049383 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL049383.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586L0218 (from clone DKFZp586L0218). /FEA=mRNA /DB_XREF=gi:4500172 /UG=Hs.58617 Rho-associated, coiled-coil containing protein kinase 2 /FL=gb:AB014519.1 gb:NM_004850.2" AL049383 "Rho-associated, coiled-coil containing protein kinase 2" ROCK2 9475 NM_004850 /// XM_005246190 0000910 // cytokinesis // non-traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006939 // smooth muscle contraction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0010825 // positive regulation of centrosome duplication // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // traceable author statement /// 0032956 // regulation of actin cytoskeleton organization // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045616 // regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051298 // centrosome duplication // inferred from mutant phenotype /// 0051492 // regulation of stress fiber assembly // traceable author statement /// 0051893 // regulation of focal adhesion assembly // traceable author statement /// 2000114 // regulation of establishment of cell polarity // traceable author statement /// 2000145 // regulation of cell motility // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 202763_at NM_004346 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004346.1 /DEF=Homo sapiens caspase 3, apoptosis-related cysteine protease (CASP3), mRNA. /FEA=mRNA /GEN=CASP3 /PROD=caspase 3, apoptosis-related cysteine protease /DB_XREF=gi:4757911 /UG=Hs.74552 caspase 3, apoptosis-related cysteine protease /FL=gb:NM_004346.1 gb:U13737.1 gb:U13738.1 gb:U26943.1" NM_004346 "caspase 3, apoptosis-related cysteine peptidase" CASP3 836 NM_004346 /// NM_032991 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030182 // neuron differentiation // not recorded /// 0030198 // extracellular matrix organization // traceable author statement /// 0030216 // keratinocyte differentiation // not recorded /// 0030218 // erythrocyte differentiation // inferred from direct assay /// 0030218 // erythrocyte differentiation // traceable author statement /// 0030220 // platelet formation // traceable author statement /// 0030264 // nuclear fragmentation involved in apoptotic nuclear change // inferred from mutant phenotype /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // traceable author statement /// 0035329 // hippo signaling // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from genetic interaction /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0046007 // negative regulation of activated T cell proliferation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0004190 // aspartic-type endopeptidase activity // not recorded /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0097153 // cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0097200 // cysteine-type endopeptidase activity involved in execution phase of apoptosis // inferred from mutant phenotype 202764_at NM_003156 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003156.1 /DEF=Homo sapiens stromal interaction molecule 1 (STIM1), mRNA. /FEA=mRNA /GEN=STIM1 /PROD=stromal interaction molecule 1 /DB_XREF=gi:4507268 /UG=Hs.74597 stromal interaction molecule 1 /FL=gb:U52426.1 gb:NM_003156.1" NM_003156 stromal interaction molecule 1 STIM1 6786 NM_001277961 /// NM_001277962 /// NM_003156 0002115 // store-operated calcium entry // inferred from electronic annotation /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0032237 // activation of store-operated calcium channel activity // inferred from direct assay /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030426 // growth cone // inferred from electronic annotation /// 0032541 // cortical endoplasmic reticulum // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0005246 // calcium channel regulator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051010 // microtubule plus-end binding // inferred from direct assay 202765_s_at AI264196 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI264196 /FEA=EST /DB_XREF=gi:3872399 /DB_XREF=est:qi20h04.x1 /CLONE=IMAGE:1857079 /UG=Hs.750 fibrillin 1 (Marfan syndrome) /FL=gb:L13923.1 gb:NM_000138.1 AI264196 fibrillin 1 FBN1 2200 NM_000138 0001501 // skeletal system development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0035583 // sequestering of TGFbeta in extracellular matrix // inferred from sequence or structural similarity 0001527 // microfibril // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202766_s_at NM_000138 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000138.1 /DEF=Homo sapiens fibrillin 1 (Marfan syndrome) (FBN1), mRNA. /FEA=mRNA /GEN=FBN1 /PROD=fibrillin 1 /DB_XREF=gi:4557590 /UG=Hs.750 fibrillin 1 (Marfan syndrome) /FL=gb:L13923.1 gb:NM_000138.1" NM_000138 fibrillin 1 FBN1 2200 NM_000138 0001501 // skeletal system development // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0035582 // sequestering of BMP in extracellular matrix // inferred from sequence or structural similarity /// 0035583 // sequestering of TGFbeta in extracellular matrix // inferred from sequence or structural similarity 0001527 // microfibril // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005604 // basement membrane // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 202767_at NM_001610 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001610.1 /DEF=Homo sapiens acid phosphatase 2, lysosomal (ACP2), mRNA. /FEA=mRNA /GEN=ACP2 /PROD=lysosomal acid phosphatase 2 precursor /DB_XREF=gi:4557009 /UG=Hs.75589 acid phosphatase 2, lysosomal /FL=gb:BC003160.1 gb:NM_001610.1" NM_001610 "acid phosphatase 2, lysosomal" ACP2 53 NM_001131064 /// NM_001610 /// XM_005252984 /// XM_005252985 /// XR_242812 0001501 // skeletal system development // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 202768_at NM_006732 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006732.1 /DEF=Homo sapiens FBJ murine osteosarcoma viral oncogene homolog B (FOSB), mRNA. /FEA=mRNA /GEN=FOSB /PROD=FBJ murine osteosarcoma viral oncogene homologB /DB_XREF=gi:5803016 /UG=Hs.75678 FBJ murine osteosarcoma viral oncogene homolog B /FL=gb:L49169.1 gb:NM_006732.1" NM_006732 FBJ murine osteosarcoma viral oncogene homolog B FOSB 2354 NM_001114171 /// NM_006732 /// XM_005258691 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007610 // behavior // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202769_at AW134535 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW134535 /FEA=EST /DB_XREF=gi:6138088 /DB_XREF=est:UI-H-BI1-abv-g-06-0-UI.s1 /CLONE=IMAGE:2713163 /UG=Hs.79069 cyclin G2 /FL=gb:U47414.1 gb:NM_004354.1 AW134535 cyclin G2 CCNG2 901 NM_004354 0000075 // cell cycle checkpoint // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 202770_s_at NM_004354 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004354.1 /DEF=Homo sapiens cyclin G2 (CCNG2), mRNA. /FEA=mRNA /GEN=CCNG2 /PROD=cyclin G2 /DB_XREF=gi:4757935 /UG=Hs.79069 cyclin G2 /FL=gb:U47414.1 gb:NM_004354.1" NM_004354 cyclin G2 CCNG2 901 NM_004354 0000075 // cell cycle checkpoint // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 202771_at NM_014745 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014745.1 /DEF=Homo sapiens KIAA0233 gene product (KIAA0233), mRNA. /FEA=mRNA /GEN=KIAA0233 /PROD=KIAA0233 gene product /DB_XREF=gi:7662013 /UG=Hs.79077 KIAA0233 gene product /FL=gb:D87071.1 gb:NM_014745.1" NM_014745 piezo-type mechanosensitive ion channel component 1 PIEZO1 9780 NM_001142864 /// XM_006721353 /// XM_006721354 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from sequence or structural similarity /// 0033625 // positive regulation of integrin activation // inferred from mutant phenotype /// 0033634 // positive regulation of cell-cell adhesion mediated by integrin // inferred from mutant phenotype /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0050982 // detection of mechanical stimulus // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005261 // cation channel activity // inferred from sequence or structural similarity /// 0008381 // mechanically-gated ion channel activity // inferred from electronic annotation 202772_at NM_000191 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000191.1 /DEF=Homo sapiens 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) (HMGCL), mRNA. /FEA=mRNA /GEN=HMGCL /PROD=3-hydroxymethyl-3-methylglutaryl-Coenzyme Alyase (hydroxymethylglutaricaciduria) /DB_XREF=gi:4504426 /UG=Hs.831 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) /FL=gb:L07033.1 gb:NM_000191.1" NM_000191 3-hydroxymethyl-3-methylglutaryl-CoA lyase HMGCL 3155 NM_000191 /// NM_001166059 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006552 // leucine catabolic process // non-traceable author statement /// 0006637 // acyl-CoA metabolic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046950 // cellular ketone body metabolic process // traceable author statement /// 0046951 // ketone body biosynthetic process // inferred from direct assay /// 0046951 // ketone body biosynthetic process // traceable author statement /// 0051262 // protein tetramerization // inferred from direct assay /// 0070542 // response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005777 // peroxisome // inferred from direct assay 0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0004419 // hydroxymethylglutaryl-CoA lyase activity // inferred from direct assay /// 0004419 // hydroxymethylglutaryl-CoA lyase activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from direct assay 202773_s_at AI023864 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI023864 /FEA=EST /DB_XREF=gi:3238908 /DB_XREF=est:ow69a07.s1 /CLONE=IMAGE:1652052 /UG=Hs.84229 splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) /FL=gb:NM_004592.1 gb:U08377.1" AI023864 "splicing factor, suppressor of white-apricot family" SFSWAP 6433 NM_001261411 /// NM_004592 /// NM_152235 /// XM_006719558 /// XM_006719559 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 202774_s_at AI871457 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI871457 /FEA=EST /DB_XREF=gi:5545506 /DB_XREF=est:wl67c04.x1 /CLONE=IMAGE:2429958 /UG=Hs.84229 splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) /FL=gb:NM_004592.1 gb:U08377.1" AI871457 "splicing factor, suppressor of white-apricot family" SFSWAP 6433 NM_001261411 /// NM_004592 /// NM_152235 /// XM_006719558 /// XM_006719559 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 202775_s_at NM_004592 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004592.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) (SFRS8), mRNA. /FEA=mRNA /GEN=SFRS8 /PROD=splicing factor, arginineserine-rich 8(suppressor-of-white-apricot, Drosophila homolog) /DB_XREF=gi:4759101 /UG=Hs.84229 splicing factor, arginineserine-rich 8 (suppressor-of-white-apricot, Drosophila homolog) /FL=gb:NM_004592.1 gb:U08377.1" NM_004592 "splicing factor, suppressor of white-apricot family" SFSWAP 6433 NM_001261411 /// NM_004592 /// NM_152235 /// XM_006719558 /// XM_006719559 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 202776_at NM_014597 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014597.1 /DEF=Homo sapiens acidic 82 kDa protein mRNA (HSU15552), mRNA. /FEA=mRNA /GEN=HSU15552 /PROD=acidic 82 kDa protein mRNA /DB_XREF=gi:7657203 /UG=Hs.85769 acidic 82 kDa protein mRNA /FL=gb:U15552.1 gb:NM_014597.1" NM_014597 "deoxynucleotidyltransferase, terminal, interacting protein 2" DNTTIP2 30836 NM_014597 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 202777_at NM_007373 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007373.1 /DEF=Homo sapiens suppressor of clear, C. elegans, homolog of (SHOC2), mRNA. /FEA=mRNA /GEN=SHOC2 /PROD=suppressor of clear, C. elegans, homolog of /DB_XREF=gi:6677944 /UG=Hs.104315 soc-2 (suppressor of clear, C.elegans) homolog /FL=gb:AF068920.1 gb:AF054828.1 gb:AB020669.1 gb:NM_007373.1" NM_007373 soc-2 suppressor of clear homolog (C. elegans) SHOC2 8036 NM_001269039 /// NM_007373 0007265 // Ras protein signal transduction // non-traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // non-traceable author statement /// 0046579 // positive regulation of Ras protein signal transduction // inferred from mutant phenotype /// 0050790 // regulation of catalytic activity // traceable author statement 0000164 // protein phosphatase type 1 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0019888 // protein phosphatase regulator activity // traceable author statement /// 0019903 // protein phosphatase binding // inferred from direct assay 202778_s_at NM_003453 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003453.1 /DEF=Homo sapiens zinc finger protein 198 (ZNF198), mRNA. /FEA=mRNA /GEN=ZNF198 /PROD=zinc finger protein 198 /DB_XREF=gi:4508010 /UG=Hs.109526 zinc finger protein 198 /FL=gb:AF035374.1 gb:AF060181.1 gb:NM_003453.1" NM_003453 "zinc finger, MYM-type 2" ZMYM2 7750 NM_001190964 /// NM_001190965 /// NM_003453 /// NM_197968 /// XM_005266517 /// XM_005266518 /// XM_005266519 /// XM_005266520 /// XM_005266521 /// XM_006719864 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016605 // PML body // inferred from direct assay 0008270 // zinc ion binding // non-traceable author statement /// 0031624 // ubiquitin conjugating enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202779_s_at NM_014501 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014501.1 /DEF=Homo sapiens ubiquitin carrier protein (E2-EPF), mRNA. /FEA=mRNA /GEN=E2-EPF /PROD=ubiquitin carrier protein /DB_XREF=gi:7657045 /UG=Hs.174070 ubiquitin carrier protein /FL=gb:M91670.1 gb:NM_014501.1" NM_014501 ubiquitin-conjugating enzyme E2S UBE2S 27338 NM_014501 0006464 // cellular protein modification process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010458 // exit from mitosis // inferred from direct assay /// 0010458 // exit from mitosis // inferred from mutant phenotype /// 0010994 // free ubiquitin chain polymerization // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0035519 // protein K29-linked ubiquitination // inferred from direct assay /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay 0005680 // anaphase-promoting complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 202780_at NM_000436 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000436.1 /DEF=Homo sapiens 3-oxoacid CoA transferase (OXCT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=OXCT /PROD=3-oxoacid CoA transferase precursor /DB_XREF=gi:4557816 /UG=Hs.177584 3-oxoacid CoA transferase /FL=gb:U62961.1 gb:NM_000436.1" NM_000436 3-oxoacid CoA transferase 1 OXCT1 5019 NM_000436 /// XR_427658 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0042182 // ketone catabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046950 // cellular ketone body metabolic process // inferred from mutant phenotype /// 0046950 // cellular ketone body metabolic process // traceable author statement /// 0046952 // ketone body catabolic process // traceable author statement /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0071229 // cellular response to acid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0008260 // 3-oxoacid CoA-transferase activity // inferred from mutant phenotype /// 0008260 // 3-oxoacid CoA-transferase activity // traceable author statement /// 0008410 // CoA-transferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement 202781_s_at AI806031 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI806031 /FEA=EST /DB_XREF=gi:5392597 /DB_XREF=est:te53d09.x1 /CLONE=IMAGE:2090417 /UG=Hs.178347 SKIP for skeletal muscle and kidney enriched inositol phosphatase /FL=gb:AB036829.1 gb:NM_016532.1 AI806031 inositol polyphosphate-5-phosphatase K INPP5K 51763 NM_001135642 /// NM_016532 /// NM_130766 /// XM_005256683 /// XM_005256685 /// XM_005256686 /// XM_006721545 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0005979 // regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010829 // negative regulation of glucose transport // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from sequence or structural similarity /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035305 // negative regulation of dephosphorylation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0072661 // protein targeting to plasma membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 0097178 // ruffle assembly // inferred from direct assay /// 2000466 // negative regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity /// 2001153 // positive regulation of renal water transport // inferred from sequence or structural similarity" 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016312 // inositol bisphosphate phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034485 // phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity // inferred from direct assay /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from direct assay /// 0034595 // phosphatidylinositol phosphate 5-phosphatase activity // inferred from mutant phenotype /// 0042577 // lipid phosphatase activity // non-traceable author statement /// 0046030 // inositol trisphosphate phosphatase activity // inferred from direct assay /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052659 // inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity // inferred from electronic annotation" 202782_s_at NM_016532 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016532.1 /DEF=Homo sapiens SKIP for skeletal muscle and kidney enriched inositol phosphatase (LOC51763), mRNA. /FEA=mRNA /GEN=LOC51763 /PROD=SKIP for skeletal muscle and kidney enrichedinositol phosphatase /DB_XREF=gi:7706564 /UG=Hs.178347 SKIP for skeletal muscle and kidney enriched inositol phosphatase /FL=gb:AB036829.1 gb:NM_016532.1" NM_016532 inositol polyphosphate-5-phosphatase K INPP5K 51763 NM_001135642 /// NM_016532 /// NM_130766 /// XM_005256683 /// XM_005256685 /// XM_005256686 /// XM_006721545 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0005979 // regulation of glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010829 // negative regulation of glucose transport // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from sequence or structural similarity /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035305 // negative regulation of dephosphorylation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045719 // negative regulation of glycogen biosynthetic process // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0051497 // negative regulation of stress fiber assembly // inferred from direct assay /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0051926 // negative regulation of calcium ion transport // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0072661 // protein targeting to plasma membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 0097178 // ruffle assembly // inferred from direct assay /// 2000466 // negative regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity /// 2001153 // positive regulation of renal water transport // inferred from sequence or structural similarity" 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0016312 // inositol bisphosphate phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034485 // phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity // inferred from direct assay /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from direct assay /// 0034595 // phosphatidylinositol phosphate 5-phosphatase activity // inferred from mutant phenotype /// 0042577 // lipid phosphatase activity // non-traceable author statement /// 0046030 // inositol trisphosphate phosphatase activity // inferred from direct assay /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052659 // inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity // inferred from electronic annotation" 202783_at U40490 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U40490.1 /DEF=Human nicotinamide nucleotide transhydrogenase mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /PROD=nicotinamide nucleotide transhydrogenase /DB_XREF=gi:1110519 /UG=Hs.18136 nicotinamide nucleotide transhydrogenase /FL=gb:U40490.1 gb:NM_012343.1" U40490 nicotinamide nucleotide transhydrogenase NNT 23530 NM_012343 /// NM_182977 /// XM_005248274 /// XM_005248275 /// XM_006714461 0006099 // tricarboxylic acid cycle // traceable author statement /// 0015992 // proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003957 // NAD(P)+ transhydrogenase (B-specific) activity // traceable author statement /// 0008746 // NAD(P)+ transhydrogenase activity // not recorded /// 0008750 // NAD(P)+ transhydrogenase (AB-specific) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay /// 0051287 // NAD binding // traceable author statement 202784_s_at NM_012343 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012343.1 /DEF=Homo sapiens nicotinamide nucleotide transhydrogenase (NNT), mRNA. /FEA=mRNA /GEN=NNT /PROD=nicotinamide nucleotide transhydrogenase /DB_XREF=gi:6912535 /UG=Hs.18136 nicotinamide nucleotide transhydrogenase /FL=gb:U40490.1 gb:NM_012343.1" NM_012343 nicotinamide nucleotide transhydrogenase NNT 23530 NM_012343 /// NM_182977 /// XM_005248274 /// XM_005248275 /// XM_006714461 0006099 // tricarboxylic acid cycle // traceable author statement /// 0015992 // proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003957 // NAD(P)+ transhydrogenase (B-specific) activity // traceable author statement /// 0008746 // NAD(P)+ transhydrogenase activity // not recorded /// 0008750 // NAD(P)+ transhydrogenase (AB-specific) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay /// 0051287 // NAD binding // traceable author statement 202785_at NM_005001 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005001.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (14.5kD, B14.5a) (NDUFA7), mRNA. /FEA=mRNA /GEN=NDUFA7 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 7 (14.5kD, B14.5a) /DB_XREF=gi:4826849 /UG=Hs.19561 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (14.5kD, B14.5a) /FL=gb:BC003102.1 gb:AF054178.1 gb:AF050637.1 gb:NM_005001.1" NM_005001 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa" NDUFA7 4701 NM_005001 /// XR_246670 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042773 // ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202786_at NM_013233 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013233.1 /DEF=Homo sapiens Ste-20 related kinase (SPAK), mRNA. /FEA=mRNA /GEN=SPAK /PROD=Ste-20 related kinase /DB_XREF=gi:7019542 /UG=Hs.199263 Ste-20 related kinase /FL=gb:AF017635.1 gb:AF099989.1 gb:AF030403.1 gb:NM_013233.1" NM_013233 serine threonine kinase 39 STK39 27347 NM_013233 /// XM_005246465 /// XM_005246466 0006468 // protein phosphorylation // non-traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0071476 // cellular hypotonic response // inferred by curator /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1901380 // negative regulation of potassium ion transmembrane transport // inferred from direct assay /// 2000681 // negative regulation of rubidium ion transport // inferred from direct assay /// 2000687 // negative regulation of rubidium ion transmembrane transporter activity // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation" 202787_s_at U43784 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U43784.1 /DEF=Human mitogen activated protein kinase activated protein kinase-3 mRNA, complete cds. /FEA=mRNA /PROD=mitogen activated protein kinase activatedprotein kinase-3 /DB_XREF=gi:1256004 /UG=Hs.227789 mitogen-activated protein kinase-activated protein kinase 3 /FL=gb:U09578.1 gb:U43784.1 gb:BC001662.1 gb:NM_004635.1" U43784 mitogen-activated protein kinase-activated protein kinase 3 MAPKAPK3 7867 NM_001243925 /// NM_001243926 /// NM_004635 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 202788_at NM_004635 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004635.1 /DEF=Homo sapiens mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3), mRNA. /FEA=mRNA /GEN=MAPKAPK3 /PROD=mitogen-activated protein kinase-activatedprotein kinase 3 /DB_XREF=gi:4758699 /UG=Hs.227789 mitogen-activated protein kinase-activated protein kinase 3 /FL=gb:U09578.1 gb:U43784.1 gb:BC001662.1 gb:NM_004635.1" NM_004635 mitogen-activated protein kinase-activated protein kinase 3 MAPKAPK3 7867 NM_001243925 /// NM_001243926 /// NM_004635 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0034097 // response to cytokine // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0044351 // macropinocytosis // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 202789_at AL022394 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL022394 /DEF=Human DNA sequence from clone RP3-511B24 on chromosome 20q11.2-12. Contains the 3 end of the TOP1 gene for topoisomerase (DNA) I, the PLCG1 gene for phospholipase C gamma 1, gene KIAA0395 for a possible homeobox protein, a 60S Ribosomal Protein L... /FEA=mRNA_1 /DB_XREF=gi:11345540 /UG=Hs.268177 phospholipase C, gamma 1 (formerly subtype 148) /FL=gb:M34667.1 gb:NM_002660.1" AL022394 "phospholipase C, gamma 1" PLCG1 5335 NM_002660 /// NM_182811 /// XM_005260438 /// XR_244143 0000186 // activation of MAPKK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009395 // phospholipid catabolic process // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019722 // calcium-mediated signaling // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008180 // COP9 signalosome // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0042995 // cell projection // inferred from direct assay 0004435 // phosphatidylinositol phospholipase C activity // inferred from direct assay /// 0004435 // phosphatidylinositol phospholipase C activity // traceable author statement /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005168 // neurotrophin TRKA receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from electronic annotation /// 0035254 // glutamate receptor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202790_at NM_001307 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001307.1 /DEF=Homo sapiens claudin 7 (CLDN7), mRNA. /FEA=mRNA /GEN=CLDN7 /PROD=claudin 7 /DB_XREF=gi:10835007 /UG=Hs.278562 claudin 7 /FL=gb:NM_001307.1 gb:BC001055.1" NM_001307 claudin 7 CLDN7 1366 NM_001185022 /// NM_001185023 /// NM_001307 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity 202791_s_at AK022669 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK022669.1 /DEF=Homo sapiens cDNA FLJ12607 fis, clone NT2RM4001489, highly similar to Homo sapiens mRNA for KIAA0685 protein. /FEA=mRNA /DB_XREF=gi:10434196 /UG=Hs.296406 KIAA0685 gene product /FL=gb:AB014585.1 gb:NM_014678.1" AK022669 "protein phosphatase 6, regulatory subunit 2" PPP6R2 9701 NM_001242898 /// NM_001242899 /// NM_001242900 /// NM_014678 /// XM_005261956 /// XM_005261957 /// XM_005261958 /// XM_005261959 /// XM_005261960 /// XM_006724428 /// XM_006724429 /// XM_006724430 /// XM_006724431 /// XM_006724432 /// XM_006724433 /// XM_006724434 /// XM_006724435 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202792_s_at NM_014678 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014678.1 /DEF=Homo sapiens KIAA0685 gene product (KIAA0685), mRNA. /FEA=mRNA /GEN=KIAA0685 /PROD=KIAA0685 gene product /DB_XREF=gi:7662251 /UG=Hs.296406 KIAA0685 gene product /FL=gb:AB014585.1 gb:NM_014678.1" NM_014678 "protein phosphatase 6, regulatory subunit 2" PPP6R2 9701 NM_001242898 /// NM_001242899 /// NM_001242900 /// NM_014678 /// XM_005261956 /// XM_005261957 /// XM_005261958 /// XM_005261959 /// XM_005261960 /// XM_006724428 /// XM_006724429 /// XM_006724430 /// XM_006724431 /// XM_006724432 /// XM_006724433 /// XM_006724434 /// XM_006724435 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202793_at NM_005768 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005768.2 /DEF=Homo sapiens putative protein similar to nessy (Drosophila) (C3F), mRNA. /FEA=mRNA /GEN=C3F /PROD=putative protein similar to nessy (Drosophila) /DB_XREF=gi:5579449 /UG=Hs.300423 putative protein similar to nessy (Drosophila) /FL=gb:BC000664.1 gb:U72515.1 gb:NM_005768.2" NM_005768 lysophosphatidylcholine acyltransferase 3 LPCAT3 10162 NM_005768 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0097006 // regulation of plasma lipoprotein particle levels // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from mutant phenotype" 202794_at NM_002194 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002194.2 /DEF=Homo sapiens inositol polyphosphate-1-phosphatase (INPP1), mRNA. /FEA=mRNA /GEN=INPP1 /PROD=inositol polyphosphate-1-phosphatase /DB_XREF=gi:4755138 /UG=Hs.32309 inositol polyphosphate-1-phosphatase /FL=gb:L08488.1 gb:NM_002194.2" NM_002194 inositol polyphosphate-1-phosphatase INPP1 3628 NM_001128928 /// NM_002194 /// XM_005246532 /// XM_006712498 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement "0004441 // inositol-1,4-bisphosphate 1-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052829 // inositol-1,3,4-trisphosphate 1-phosphatase activity // traceable author statement" 202795_x_at NM_007032 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007032.1 /DEF=Homo sapiens putative nuclear protein (HRIHFB2122), mRNA. /FEA=mRNA /GEN=HRIHFB2122 /PROD=putative nuclear protein /DB_XREF=gi:10334853 /UG=Hs.40342 putative nuclear protein /FL=gb:NM_007032.1" NM_007032 TRIO and F-actin binding protein TRIOBP 11078 NM_001039141 /// NM_007032 /// NM_138632 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030047 // actin modification // non-traceable author statement /// 0051016 // barbed-end actin filament capping // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0030496 // midbody // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017049 // GTP-Rho binding // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0045159 // myosin II binding // non-traceable author statement /// 0051015 // actin filament binding // inferred from direct assay 202796_at NM_007286 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007286.1 /DEF=Homo sapiens synaptopodin (KIAA1029), mRNA. /FEA=mRNA /GEN=KIAA1029 /PROD=synaptopodin /DB_XREF=gi:6005797 /UG=Hs.5307 synaptopodin /FL=gb:AB028952.1 gb:NM_007286.1" NM_007286 synaptopodin SYNPO 11346 NM_001109974 /// NM_001166208 /// NM_001166209 /// NM_007286 /// XM_005268369 /// XM_005268370 /// XM_005268371 /// XM_006714755 0032233 // positive regulation of actin filament bundle assembly // inferred from electronic annotation /// 0032233 // positive regulation of actin filament bundle assembly // inferred from sequence or structural similarity /// 0051492 // regulation of stress fiber assembly // inferred from electronic annotation /// 0051492 // regulation of stress fiber assembly // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 202797_at NM_014016 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014016.1 /DEF=Homo sapiens KIAA0851 protein (KIAA0851), mRNA. /FEA=mRNA /GEN=KIAA0851 /PROD=KIAA0851 protein /DB_XREF=gi:7662337 /UG=Hs.5867 KIAA0851 protein /FL=gb:AB020658.1 gb:AL136831.1 gb:NM_014016.1" NM_014016 SAC1 suppressor of actin mutations 1-like (yeast) SACM1L 22908 NM_014016 /// XR_427259 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation /// 0032281 // alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex // inferred from electronic annotation 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from sequence or structural similarity /// 0034593 // phosphatidylinositol bisphosphate phosphatase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation /// 0043812 // phosphatidylinositol-4-phosphate phosphatase activity // inferred from electronic annotation 202798_at NM_006323 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006323.1 /DEF=Homo sapiens SEC24 (S. cerevisiae) related gene family, member B (SEC24B), mRNA. /FEA=mRNA /GEN=SEC24B /PROD=SEC24 (S. cerevisiae) related gene family,member B /DB_XREF=gi:5454045 /UG=Hs.7239 SEC24 (S. cerevisiae) related gene family, member B /FL=gb:NM_006323.1" NM_006323 SEC24 family member B SEC24B 10427 NM_001042734 /// NM_006323 /// XM_005262688 /// XM_005262689 /// XM_005262691 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 202799_at NM_006012 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006012.1 /DEF=Homo sapiens ClpP (caseinolytic protease, ATP-dependent, proteolytic subunit, E. coli) homolog (CLPP), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CLPP /PROD=endopeptidase Clp precursor /DB_XREF=gi:5174418 /UG=Hs.74362 ClpP (caseinolytic protease, ATP-dependent, proteolytic subunit, E. coli) homolog /FL=gb:BC002956.1 gb:NM_006012.1" NM_006012 caseinolytic mitochondrial matrix peptidase proteolytic subunit CLPP 8192 NM_006012 0006508 // proteolysis // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0009368 // endopeptidase Clp complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // traceable author statement /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 202800_at NM_004172 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004172.1 /DEF=Homo sapiens solute carrier family 1 (glial high affinity glutamate transporter), member 3 (SLC1A3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC1A3 /PROD=solute carrier family 1 (glial high affinityglutamate transporter), member 3 /DB_XREF=gi:4759125 /UG=Hs.75379 solute carrier family 1 (glial high affinity glutamate transporter), member 3 /FL=gb:D26443.1 gb:NM_004172.1 gb:U03504.1" NM_004172 "solute carrier family 1 (glial high affinity glutamate transporter), member 3" SLC1A3 6507 NM_001166695 /// NM_001166696 /// NM_001289939 /// NM_001289940 /// NM_004172 /// XM_005248342 /// XM_006714488 0001504 // neurotransmitter uptake // traceable author statement /// 0006536 // glutamate metabolic process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009449 // gamma-aminobutyric acid biosynthetic process // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from electronic annotation /// 0031223 // auditory behavior // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070779 // D-aspartate import // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043205 // fibril // inferred from electronic annotation 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005314 // high-affinity glutamate transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016597 // amino acid binding // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation 202801_at NM_002730 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002730.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, catalytic, alpha (PRKACA), mRNA. /FEA=mRNA /GEN=PRKACA /PROD=protein kinase, cAMP-dependent, catalytic,alpha /DB_XREF=gi:4506054 /UG=Hs.77271 protein kinase, cAMP-dependent, catalytic, alpha /FL=gb:NM_002730.1" NM_002730 "protein kinase, cAMP-dependent, catalytic, alpha" PRKACA 5566 NM_002730 /// NM_207518 /// XM_005259984 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0002027 // regulation of heart rate // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0019433 // triglyceride catabolic process // traceable author statement /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0035584 // calcium-mediated signaling using intracellular calcium source // traceable author statement /// 0043393 // regulation of protein binding // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045667 // regulation of osteoblast differentiation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048240 // sperm capacitation // inferred from sequence or structural similarity /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050804 // regulation of synaptic transmission // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055117 // regulation of cardiac muscle contraction // traceable author statement /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0061136 // regulation of proteasomal protein catabolic process // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from direct assay /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // traceable author statement /// 2000810 // regulation of tight junction assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0005952 // cAMP-dependent protein kinase complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031588 // AMP-activated protein kinase complex // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0034704 // calcium channel complex // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097225 // sperm midpiece // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004691 // cAMP-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004691 // cAMP-dependent protein kinase activity // non-traceable author statement /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from physical interaction" 202802_at NM_001930 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001930.2 /DEF=Homo sapiens deoxyhypusine synthase (DHPS), transcript variant 1, mRNA. /FEA=mRNA /GEN=DHPS /PROD=deoxyhypusine synthase isoform a /DB_XREF=gi:7108341 /UG=Hs.79064 deoxyhypusine synthase /FL=gb:U40579.1 gb:BC000333.1 gb:U32178.1 gb:U79262.1 gb:NM_001930.2 gb:L39068.1" NM_001930 deoxyhypusine synthase DHPS 1725 NM_001206974 /// NM_001930 /// NM_013406 /// NM_013407 /// NR_038192 0006412 // translation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008612 // peptidyl-lysine modification to peptidyl-hypusine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050983 // deoxyhypusine biosynthetic process from spermidine // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0034038 // deoxyhypusine synthase activity // traceable author statement 202803_s_at NM_000211 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000211.1 /DEF=Homo sapiens integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) (ITGB2), mRNA. /FEA=mRNA /GEN=ITGB2 /PROD=integrin beta chain, beta 2 precursor /DB_XREF=gi:4557885 /UG=Hs.83968 integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) /FL=gb:NM_000211.1" NM_000211 "integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)" ITGB2 3689 NM_000211 /// NM_001127491 /// XM_006724001 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // non-traceable author statement /// 0006954 // inflammatory response // non-traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007267 // cell-cell signaling // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202804_at AI539710 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI539710 /FEA=EST /DB_XREF=gi:4453845 /DB_XREF=est:tp77b05.x1 /CLONE=IMAGE:2205297 /UG=Hs.89433 ATP-binding cassette, sub-family C (CFTRMRP), member 1 /FL=gb:L05628.1 gb:NM_004996.2" AI539710 "ATP-binding cassette, sub-family C (CFTR/MRP), member 1" ABCC1 4363 NM_004996 /// NM_019862 /// NM_019898 /// NM_019899 /// NM_019900 /// NM_019901 /// NM_019902 /// XM_005255327 /// XM_005255328 /// XM_005255329 /// XM_006720884 /// XM_006720885 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation" 202805_s_at NM_004996 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004996.2 /DEF=Homo sapiens ATP-binding cassette, sub-family C (CFTRMRP), member 1 (ABCC1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ABCC1 /PROD=ATP-binding cassette, sub-family C, member 1,isoform 1 /DB_XREF=gi:9955961 /UG=Hs.89433 ATP-binding cassette, sub-family C (CFTRMRP), member 1 /FL=gb:L05628.1 gb:NM_004996.2" NM_004996 "ATP-binding cassette, sub-family C (CFTR/MRP), member 1" ABCC1 4363 NM_004996 /// NM_019862 /// NM_019898 /// NM_019899 /// NM_019900 /// NM_019901 /// NM_019902 /// XM_005255327 /// XM_005255328 /// XM_005255329 /// XM_006720884 /// XM_006720885 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation" 202806_at NM_004395 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004395.1 /DEF=Homo sapiens drebrin 1 (DBN1), mRNA. /FEA=mRNA /GEN=DBN1 /PROD=drebrin 1 /DB_XREF=gi:4758123 /UG=Hs.89434 drebrin 1 /FL=gb:BC000283.1 gb:U00802.1 gb:NM_004395.1 gb:D17530.1" NM_004395 drebrin 1 DBN1 1627 NM_004395 /// NM_080881 /// XM_005265827 /// XM_005265828 /// XM_005265829 /// XM_006714826 0007015 // actin filament organization // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0010643 // cell communication by chemical coupling // inferred from electronic annotation /// 0010644 // cell communication by electrical coupling // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032507 // maintenance of protein location in cell // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // non-traceable author statement /// 0048699 // generation of neurons // inferred from electronic annotation /// 0050773 // regulation of dendrite development // non-traceable author statement /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // non-traceable author statement /// 0042641 // actomyosin // non-traceable author statement 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005522 // profilin binding // inferred from sequence or structural similarity 202807_s_at NM_005488 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005488.1 /DEF=Homo sapiens target of myb1 (chicken) homolog (TOM1), mRNA. /FEA=mRNA /GEN=TOM1 /PROD=target of myb1 (chicken) homolog /DB_XREF=gi:4885636 /UG=Hs.9482 target of myb1 (chicken) homolog /FL=gb:NM_005488.1" NM_005488 target of myb1 (chicken) TOM1 10043 NM_001135729 /// NM_001135730 /// NM_001135732 /// NM_005488 /// NR_024194 /// NR_024195 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // non-traceable author statement /// 0015031 // protein transport // non-traceable author statement /// 0016197 // endosomal transport // non-traceable author statement /// 0016197 // endosomal transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // traceable author statement /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from direct assay 202808_at AK000161 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK000161.1 /DEF=Homo sapiens cDNA FLJ20154 fis, clone COL08740. /FEA=mRNA /DB_XREF=gi:7020067 /UG=Hs.10346 hypothetical protein FLJ20154 /FL=gb:NM_017787.1" AK000161 WW domain binding protein 1-like WBP1L 54838 NM_001083913 /// NM_017787 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202809_s_at NM_023015 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_023015.1 /DEF=Homo sapiens hypothetical protein FLJ21919 (FLJ21919), mRNA. /FEA=mRNA /GEN=FLJ21919 /PROD=hypothetical protein FLJ21919 /DB_XREF=gi:12711679 /UG=Hs.105894 hypothetical protein FLJ21919 /FL=gb:NM_023015.1" NM_023015 integrator complex subunit 3 INTS3 65123 NM_023015 /// XM_005245459 /// XM_005245461 /// XM_005276735 /// XM_005276737 /// XM_006711490 /// XM_006711491 /// XM_006726204 /// XM_006726205 /// XR_241094 /// XR_254195 0006281 // DNA repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay /// 0070876 // SOSS complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202810_at NM_004147 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004147.1 /DEF=Homo sapiens developmentally regulated GTP-binding protein 1 (DRG1), mRNA. /FEA=mRNA /GEN=DRG1 /PROD=developmentally regulated GTP-binding protein 1 /DB_XREF=gi:4758795 /UG=Hs.115242 developmentally regulated GTP-binding protein 1 /FL=gb:AF078103.1 gb:NM_004147.1" NM_004147 developmentally regulated GTP binding protein 1 DRG1 4733 NM_004147 "0006351 // transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0015684 // ferrous iron transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // traceable author statement /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202811_at NM_006463 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006463.1 /DEF=Homo sapiens associated molecule with the SH3 domain of STAM (AMSH), mRNA. /FEA=mRNA /GEN=AMSH /PROD=associated molecule with the SH3 domain of STAM /DB_XREF=gi:5453544 /UG=Hs.12479 associated molecule with the SH3 domain of STAM /FL=gb:U73522.1 gb:NM_006463.1" NM_006463 STAM binding protein STAMBP 10617 NM_006463 /// NM_201647 /// NM_213622 /// XM_005264088 /// XM_005264091 /// XM_006711920 /// XM_006711921 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202812_at NM_000152 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000152.2 /DEF=Homo sapiens glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) (GAA), mRNA. /FEA=mRNA /GEN=GAA /PROD=acid alpha-glucosidase preproprotein /DB_XREF=gi:11496988 /UG=Hs.1437 glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) /FL=gb:NM_000152.2 gb:M34424.1" NM_000152 "glucosidase, alpha; acid" GAA 2548 NM_000152 /// NM_001079803 /// NM_001079804 /// XM_005257193 /// XM_005257194 0000023 // maltose metabolic process // inferred by curator /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002086 // diaphragm contraction // inferred from mutant phenotype /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // inferred from direct assay /// 0005985 // sucrose metabolic process // inferred by curator /// 0006006 // glucose metabolic process // inferred by curator /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from mutant phenotype /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009888 // tissue development // inferred from electronic annotation /// 0043181 // vacuolar sequestering // inferred from mutant phenotype /// 0043587 // tongue morphogenesis // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004558 // alpha-glucosidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0032450 // maltose alpha-glucosidase activity // inferred from electronic annotation" 202813_at NM_005646 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005646.1 /DEF=Homo sapiens TAR (HIV) RNA-binding protein 1 (TARBP1), mRNA. /FEA=mRNA /GEN=TARBP1 /PROD=TAR (HIV) RNA-binding protein 1 /DB_XREF=gi:5032156 /UG=Hs.151518 TAR (HIV) RNA-binding protein 1 /FL=gb:U38847.1 gb:NM_005646.1" NM_005646 TAR (HIV-1) RNA binding protein 1 TARBP1 6894 NM_005646 /// XM_005273234 /// XM_006711812 0001510 // RNA methylation // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008173 // RNA methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 202814_s_at AW193511 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW193511 /FEA=EST /DB_XREF=gi:6472210 /DB_XREF=est:xm17b10.x1 /CLONE=IMAGE:2684443 /UG=Hs.15299 HMBA-inducible /FL=gb:AB021179.1 gb:NM_006460.1 AW193511 hexamethylene bis-acetamide inducible 1 HEXIM1 10614 NM_006460 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from direct assay 202815_s_at NM_006460 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006460.1 /DEF=Homo sapiens HMBA-inducible (HIS1), mRNA. /FEA=mRNA /GEN=HIS1 /PROD=HMBA-inducible /DB_XREF=gi:5453681 /UG=Hs.15299 HMBA-inducible /FL=gb:AB021179.1 gb:NM_006460.1" NM_006460 hexamethylene bis-acetamide inducible 1 HEXIM1 10614 NM_006460 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017069 // snRNA binding // inferred from direct assay 202816_s_at AW292882 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW292882 /FEA=EST /DB_XREF=gi:6699518 /DB_XREF=est:UI-H-BW0-aif-g-06-0-UI.s1 /CLONE=IMAGE:2729267 /UG=Hs.153221 synovial sarcoma, translocated to X chromosome /FL=gb:NM_005637.1" AW292882 "synovial sarcoma translocation, chromosome 18" SS18 6760 NM_001007559 /// NM_005637 /// XM_005258334 /// XM_006722527 "0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 202817_s_at NM_005637 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005637.1 /DEF=Homo sapiens synovial sarcoma, translocated to X chromosome (SSXT), mRNA. /FEA=mRNA /GEN=SSXT /PROD=synovial sarcoma, translocated to X chromosome /DB_XREF=gi:5032124 /UG=Hs.153221 synovial sarcoma, translocated to X chromosome /FL=gb:NM_005637.1" NM_005637 "synovial sarcoma translocation, chromosome 18" SS18 6760 NM_001007559 /// NM_005637 /// XM_005258334 /// XM_006722527 "0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay 202818_s_at AI344128 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI344128 /FEA=EST /DB_XREF=gi:4081334 /DB_XREF=est:tc02c08.x1 /CLONE=IMAGE:2062670 /UG=Hs.155202 transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A) /FL=gb:BC002883.1 gb:NM_003198.1 gb:L47345.1" AI344128 "transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)" TCEB3 6924 NM_003198 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202819_s_at NM_003198 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003198.1 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A) (TCEB3), mRNA. /FEA=mRNA /GEN=TCEB3 /PROD=elongin A /DB_XREF=gi:4507388 /UG=Hs.155202 transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A) /FL=gb:BC002883.1 gb:NM_003198.1 gb:L47345.1" NM_003198 "transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)" TCEB3 6924 NM_003198 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 202820_at NM_001621 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001621.2 /DEF=Homo sapiens aryl hydrocarbon receptor (AHR), mRNA. /FEA=mRNA /GEN=AHR /PROD=aryl hydrocarbon receptor /DB_XREF=gi:5016091 /UG=Hs.170087 aryl hydrocarbon receptor /FL=gb:L19872.1 gb:D16354.1 gb:NM_001621.2" NM_001621 aryl hydrocarbon receptor AHR 196 NM_001621 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001568 // blood vessel development // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from direct assay /// 0007049 // cell cycle // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from direct assay /// 0010468 // regulation of gene expression // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030888 // regulation of B cell proliferation // inferred from direct assay /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045899 // positive regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0034752 // cytosolic aryl hydrocarbon receptor complex // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // traceable author statement /// 0046983 // protein dimerization activity // traceable author statement /// 0051879 // Hsp90 protein binding // inferred from direct assay /// 0070888 // E-box binding // inferred from sequence or structural similarity 202821_s_at AL044018 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL044018 /FEA=EST /DB_XREF=gi:5935931 /DB_XREF=est:DKFZp434J1028_s1 /CLONE=DKFZp434J1028 /UG=Hs.180398 LIM domain-containing preferred translocation partner in lipoma /FL=gb:NM_005578.1 AL044018 LIM domain containing preferred translocation partner in lipoma LPP 4026 NM_001167671 /// NM_001167672 /// NM_005578 /// XM_005247444 /// XM_005247445 /// XM_005247446 /// XM_005247447 /// XM_005247448 /// XM_005247450 /// XM_005247451 /// XM_005247453 /// XM_006713637 0007155 // cell adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202822_at BF221852 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF221852 /FEA=EST /DB_XREF=gi:11129029 /DB_XREF=est:7p37f11.x1 /CLONE=IMAGE:3648141 /UG=Hs.180398 LIM domain-containing preferred translocation partner in lipoma /FL=gb:NM_005578.1 BF221852 LIM domain containing preferred translocation partner in lipoma LPP 4026 NM_001167671 /// NM_001167672 /// NM_005578 /// XM_005247444 /// XM_005247445 /// XM_005247446 /// XM_005247447 /// XM_005247448 /// XM_005247450 /// XM_005247451 /// XM_005247453 /// XM_006713637 0007155 // cell adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202823_at N89607 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N89607 /FEA=EST /DB_XREF=gi:1442934 /DB_XREF=est:zb08h02.s1 /CLONE=IMAGE:301491 /UG=Hs.184693 transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C) /FL=gb:NM_005648.1 gb:L34587.1" N89607 "transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)" TCEB1 6921 NM_001204857 /// NM_001204858 /// NM_001204859 /// NM_001204860 /// NM_001204861 /// NM_001204862 /// NM_001204863 /// NM_001204864 /// NM_005648 /// XM_005251290 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0070449 // elongin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202824_s_at NM_005648 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005648.1 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C) (TCEB1), mRNA. /FEA=mRNA /GEN=TCEB1 /PROD=elongin C /DB_XREF=gi:5032160 /UG=Hs.184693 transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C) /FL=gb:NM_005648.1 gb:L34587.1" NM_005648 "transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)" TCEB1 6921 NM_001204857 /// NM_001204858 /// NM_001204859 /// NM_001204860 /// NM_001204861 /// NM_001204862 /// NM_001204863 /// NM_001204864 /// NM_005648 /// XM_005251290 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032968 // positive regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0070449 // elongin complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202825_at NM_001151 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001151.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 (SLC25A4), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC25A4 /PROD=solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 4 /DB_XREF=gi:4502096 /UG=Hs.2043 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 /FL=gb:J02966.1 gb:NM_001151.1" NM_001151 "solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4" SLC25A4 291 NM_001151 0000002 // mitochondrial genome maintenance // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0015853 // adenine transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060546 // negative regulation of necroptotic process // inferred from mutant phenotype /// 0060547 // negative regulation of necrotic cell death // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015207 // adenine transmembrane transporter activity // traceable author statement 202826_at NM_003710 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003710.1 /DEF=Homo sapiens serine protease inhibitor, Kunitz type 1 (SPINT1), mRNA. /FEA=mRNA /GEN=SPINT1 /PROD=hepatocyte growth factor activator inhibitorprecursor /DB_XREF=gi:4504328 /UG=Hs.233950 serine protease inhibitor, Kunitz type 1 /FL=gb:BC004140.1 gb:AB000095.1 gb:NM_003710.1" NM_003710 "serine peptidase inhibitor, Kunitz type 1" SPINT1 6692 NM_001032367 /// NM_003710 /// NM_181642 /// XM_006720657 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060674 // placenta blood vessel development // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 202827_s_at AU149305 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU149305 /FEA=EST /DB_XREF=gi:11010826 /DB_XREF=est:AU149305 /CLONE=NT2RM4002036 /UG=Hs.2399 matrix metalloproteinase 14 (membrane-inserted) /FL=gb:U41078.1 gb:NM_004995.2 AU149305 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 "0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202828_s_at NM_004995 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004995.2 /DEF=Homo sapiens matrix metalloproteinase 14 (membrane-inserted) (MMP14), mRNA. /FEA=mRNA /GEN=MMP14 /PROD=matrix metalloproteinase 14 preproprotein /DB_XREF=gi:13027797 /UG=Hs.2399 matrix metalloproteinase 14 (membrane-inserted) /FL=gb:U41078.1 gb:NM_004995.2" NM_004995 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 "0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202829_s_at NM_005638 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005638.1 /DEF=Homo sapiens synaptobrevin-like 1 (SYBL1), mRNA. /FEA=mRNA /GEN=SYBL1 /PROD=synaptobrevin-like 1 /DB_XREF=gi:5032136 /UG=Hs.24167 synaptobrevin-like 1 /FL=gb:NM_005638.1" NM_005638 vesicle-associated membrane protein 7 VAMP7 6845 NM_001145149 /// NM_001185183 /// NM_005638 /// NR_033714 /// NR_033715 /// XM_006724835 /// XM_006724881 "0000046 // autophagic vacuole fusion // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // not recorded /// 0006906 // vesicle fusion // inferred from direct assay /// 0006911 // phagocytosis, engulfment // inferred from sequence or structural similarity /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from direct assay /// 0017156 // calcium ion-dependent exocytosis // inferred from sequence or structural similarity /// 0034197 // triglyceride transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0043308 // eosinophil degranulation // inferred from sequence or structural similarity /// 0043312 // neutrophil degranulation // inferred from sequence or structural similarity /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 1900483 // regulation of protein targeting to vacuolar membrane // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031201 // SNARE complex // inferred from direct assay /// 0031201 // SNARE complex // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045335 // phagocytic vesicle // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0005484 // SNAP receptor activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation 202830_s_at NM_001467 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001467.1 /DEF=Homo sapiens glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1 (G6PT1), mRNA. /FEA=mRNA /GEN=G6PT1 /PROD=glucose-6-phosphatase, transport(glucose-6-phosphate) protein 1 /DB_XREF=gi:4503846 /UG=Hs.26655 glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1 /FL=gb:BC002400.1 gb:BC003589.1 gb:NM_001467.1 gb:AF110819.1" NM_001467 "solute carrier family 37 (glucose-6-phosphate transporter), member 4" SLC37A4 2542 NM_001164277 /// NM_001164278 /// NM_001164279 /// NM_001164280 /// NM_001467 0001780 // neutrophil homeostasis // inferred from electronic annotation /// 0001816 // cytokine production // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // non-traceable author statement /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // non-traceable author statement /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0008645 // hexose transport // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0015760 // glucose-6-phosphate transport // inferred from direct assay /// 0015760 // glucose-6-phosphate transport // inferred from mutant phenotype /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032682 // negative regulation of chemokine production // inferred from electronic annotation /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045730 // respiratory burst // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015152 // glucose-6-phosphate transmembrane transporter activity // inferred from direct assay /// 0015152 // glucose-6-phosphate transmembrane transporter activity // inferred from mutant phenotype 202831_at NM_002083 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002083.1 /DEF=Homo sapiens glutathione peroxidase 2 (gastrointestinal) (GPX2), mRNA. /FEA=mRNA /GEN=GPX2 /PROD=gastrointestinal glutathione peroxidase 2 /DB_XREF=gi:4504102 /UG=Hs.2704 glutathione peroxidase 2 (gastrointestinal) /FL=gb:NM_002083.1" NM_002083 glutathione peroxidase 2 (gastrointestinal) GPX2 2877 NM_002083 /// NR_046320 /// NR_046321 0001659 // temperature homeostasis // inferred from electronic annotation /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0009609 // response to symbiotic bacterium // inferred from electronic annotation /// 0051702 // interaction with symbiont // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 202832_at NM_014635 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014635.1 /DEF=Homo sapiens KIAA0336 gene product (KIAA0336), mRNA. /FEA=mRNA /GEN=KIAA0336 /PROD=KIAA0336 gene product /DB_XREF=gi:7662061 /UG=Hs.278671 KIAA0336 gene product /FL=gb:AF273042.1 gb:AB002334.1 gb:NM_014635.1" NM_014635 GRIP and coiled-coil domain containing 2 GCC2 9648 NM_181453 /// NR_028063 /// XM_006712870 /// XM_006712871 /// XM_006712872 /// XR_427125 "0000042 // protein targeting to Golgi // inferred from electronic annotation /// 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0031023 // microtubule organizing center organization // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0034453 // microtubule anchoring // inferred from mutant phenotype /// 0034499 // late endosome to Golgi transport // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype /// 0070861 // regulation of protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0071955 // recycling endosome to Golgi transport // inferred from mutant phenotype /// 0090161 // Golgi ribbon formation // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 202833_s_at NM_000295 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000295.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), mRNA. /FEA=mRNA /GEN=SERPINA1 /PROD=serine (or cysteine) proteinase inhibitor, cladeA (alpha-1 antiproteinase, antitrypsin), member 1 /DB_XREF=gi:4505792 /UG=Hs.297681 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 /FL=gb:AF130068.1 gb:M11465.1 gb:K01396.1 gb:NM_000295.1" NM_000295 "serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1" SERPINA1 5265 NM_000295 /// NM_001002235 /// NM_001002236 /// NM_001127700 /// NM_001127701 /// NM_001127702 /// NM_001127703 /// NM_001127704 /// NM_001127705 /// NM_001127706 /// NM_001127707 0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033986 // response to methanol // inferred from electronic annotation /// 0034014 // response to triglyceride // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0046687 // response to chromate // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 202834_at NM_000029 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000029.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 (SERPINA8), mRNA. /FEA=mRNA /GEN=SERPINA8 /PROD=angiotensinogen precursor /DB_XREF=gi:4557286 /UG=Hs.3697 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 /FL=gb:K02215.1 gb:NM_000029.1" NM_000029 "angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" AGT 183 NM_000029 "0001543 // ovarian follicle rupture // inferred from electronic annotation /// 0001558 // regulation of cell growth // non-traceable author statement /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // traceable author statement /// 0001822 // kidney development // inferred from mutant phenotype /// 0001974 // blood vessel remodeling // traceable author statement /// 0001991 // regulation of systemic arterial blood pressure by circulatory renin-angiotensin // inferred from electronic annotation /// 0001998 // angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0001999 // renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0002003 // angiotensin maturation // traceable author statement /// 0002016 // regulation of blood volume by renin-angiotensin // non-traceable author statement /// 0002018 // renin-angiotensin regulation of aldosterone production // non-traceable author statement /// 0002019 // regulation of renal output by angiotensin // non-traceable author statement /// 0002034 // regulation of blood vessel size by renin-angiotensin // traceable author statement /// 0002035 // brain renin-angiotensin system // inferred from electronic annotation /// 0003014 // renal system process // inferred from direct assay /// 0003051 // angiotensin-mediated drinking behavior // inferred from electronic annotation /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred from electronic annotation /// 0003331 // positive regulation of extracellular matrix constituent secretion // inferred from electronic annotation /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007202 // activation of phospholipase C activity // inferred from electronic annotation /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008065 // establishment of blood-nerve barrier // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from mutant phenotype /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014061 // regulation of norepinephrine secretion // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from electronic annotation /// 0014873 // response to muscle activity involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // non-traceable author statement /// 0030162 // regulation of proteolysis // not recorded /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030432 // peristalsis // inferred from electronic annotation /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from electronic annotation /// 0033864 // positive regulation of NAD(P)H oxidase activity // traceable author statement /// 0034104 // negative regulation of tissue remodeling // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // non-traceable author statement /// 0035411 // catenin import into nucleus // inferred from electronic annotation /// 0035813 // regulation of renal sodium excretion // non-traceable author statement /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042445 // hormone metabolic process // inferred from electronic annotation /// 0042756 // drinking behavior // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0045742 // positive regulation of epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046622 // positive regulation of organ growth // inferred from electronic annotation /// 0048143 // astrocyte activation // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048659 // smooth muscle cell proliferation // inferred from electronic annotation /// 0050663 // cytokine secretion // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from direct assay /// 0051403 // stress-activated MAPK cascade // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0061049 // cell growth involved in cardiac muscle cell development // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 0070371 // ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070471 // uterine smooth muscle contraction // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // traceable author statement /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from direct assay" 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred by curator /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0005179 // hormone activity // inferred by curator /// 0005179 // hormone activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0010698 // acetyltransferase activator activity // inferred from direct assay /// 0031701 // angiotensin receptor binding // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from physical interaction /// 0031703 // type 2 angiotensin receptor binding // inferred from physical interaction 202835_at BC001046 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001046.1 /DEF=Homo sapiens, similar to S. pombe dim1+, clone MGC:1296, mRNA, complete cds. /FEA=mRNA /PROD=similar to S. pombe dim1+ /DB_XREF=gi:12654440 /UG=Hs.5074 similar to S. pombe dim1+ /FL=gb:BC001046.1 gb:AF023611.1 gb:NM_006701.1 gb:AF146373.1" BC001046 thioredoxin-like 4A TXNL4A 10907 NM_006701 /// XM_005266645 "0000245 // spliceosomal complex assembly // traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202836_s_at NM_006701 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006701.1 /DEF=Homo sapiens similar to S. pombe dim1+ (DIM1), mRNA. /FEA=mRNA /GEN=DIM1 /PROD=similar to S. pombe dim1+ /DB_XREF=gi:5729801 /UG=Hs.5074 similar to S. pombe dim1+ /FL=gb:BC001046.1 gb:AF023611.1 gb:NM_006701.1 gb:AF146373.1" NM_006701 thioredoxin-like 4A TXNL4A 10907 NM_006701 /// XM_005266645 "0000245 // spliceosomal complex assembly // traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202837_at NM_006700 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006700.1 /DEF=Homo sapiens FLN29 gene product (FLN29), mRNA. /FEA=mRNA /GEN=FLN29 /PROD=FLN29 gene product /DB_XREF=gi:5729827 /UG=Hs.5148 FLN29 gene product /FL=gb:BC003553.1 gb:AB007447.1 gb:NM_006700.1" NM_006700 TRAF-type zinc finger domain containing 1 TRAFD1 10906 NM_001143906 /// NM_006700 0034097 // response to cytokine // inferred from electronic annotation /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202838_at NM_000147 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000147.1 /DEF=Homo sapiens fucosidase, alpha-L- 1, tissue (FUCA1), mRNA. /FEA=mRNA /GEN=FUCA1 /PROD=fucosidase, alpha-L- 1, tissue /DB_XREF=gi:4503802 /UG=Hs.576 fucosidase, alpha-L- 1, tissue /FL=gb:M29877.1 gb:NM_000147.1" NM_000147 "fucosidase, alpha-L- 1, tissue" FUCA1 2517 NM_000147 /// XM_005245821 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006004 // fucose metabolic process // inferred from direct assay /// 0006027 // glycosaminoglycan catabolic process // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016139 // glycoside catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred by curator /// 0005764 // lysosome // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004560 // alpha-L-fucosidase activity // inferred from direct assay /// 0004560 // alpha-L-fucosidase activity // traceable author statement /// 0015928 // fucosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042806 // fucose binding // not recorded" 202839_s_at NM_004146 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004146.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 (18kD, B18) (NDUFB7), mRNA. /FEA=mRNA /GEN=NDUFB7 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 7 (18kD, B18) /DB_XREF=gi:10764846 /UG=Hs.661 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 (18kD, B18) /FL=gb:NM_004146.2 gb:BC002595.1 gb:AF112200.1 gb:AF217091.1" NM_004146 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa" NDUFB7 4713 NM_004146 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 202840_at NM_003487 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003487.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) (TAF2N), mRNA. /FEA=mRNA /GEN=TAF2N /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, N, 68kD (RNA-binding protein56) /DB_XREF=gi:4507352 /UG=Hs.66772 TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) /FL=gb:U51334.1 gb:NM_003487.1" NM_003487 "TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa" TAF15 8148 NM_003487 /// NM_139215 "0045893 // positive regulation of transcription, DNA-templated // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202841_x_at NM_007346 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007346.1 /DEF=Homo sapiens 7-60 protein (7-60), mRNA. /FEA=mRNA /GEN=7-60 /PROD=7-60 protein /DB_XREF=gi:6671492 /UG=Hs.67896 7-60 protein /FL=gb:AF109134.1 gb:NM_007346.1 gb:AF172451.1" NM_007346 opioid growth factor receptor OGFR 11054 NM_007346 0001558 // regulation of cell growth // non-traceable author statement /// 0038003 // opioid receptor signaling pathway // non-traceable author statement /// 0040008 // regulation of growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004985 // opioid receptor activity // non-traceable author statement 202842_s_at AL080081 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AL080081.1 /DEF=Homo sapiens mRNA; cDNA DKFZp564F1862 (from clone DKFZp564F1862); complete cds. /FEA=mRNA /GEN=DKFZp564F1862 /PROD=hypothetical protein /DB_XREF=gi:5262493 /UG=Hs.6790 DnaJ (Hsp40) homolog, subfamily B, member 9 /FL=gb:AF083247.1 gb:AL080081.1 gb:AB026908.1 gb:NM_012328.1" AL080081 "DnaJ (Hsp40) homolog, subfamily B, member 9" DNAJB9 4189 NM_012328 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay 202843_at NM_012328 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012328.1 /DEF=Homo sapiens microvascular endothelial differentiation gene 1 (MDG1), mRNA. /FEA=mRNA /GEN=MDG1 /PROD=microvascular endothelial differentiation gene1 /DB_XREF=gi:9558754 /UG=Hs.6790 DnaJ (Hsp40) homolog, subfamily B, member 9 /FL=gb:AF083247.1 gb:AL080081.1 gb:AB026908.1 gb:NM_012328.1" NM_012328 "DnaJ (Hsp40) homolog, subfamily B, member 9" DNAJB9 4189 NM_012328 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005730 // nucleolus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay 202844_s_at AW025261 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW025261 /FEA=EST /DB_XREF=gi:5878791 /DB_XREF=est:wu95f02.x1 /CLONE=IMAGE:2527803 /UG=Hs.75447 ralA binding protein 1 /FL=gb:NM_006788.1 gb:L42542.1 AW025261 ralA binding protein 1 RALBP1 10928 NM_006788 /// XM_006722295 /// XM_006722296 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from physical interaction /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay "0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0043492 // ATPase activity, coupled to movement of substances // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from physical interaction" 202845_s_at NM_006788 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006788.1 /DEF=Homo sapiens ralA binding protein 1 (RALBP1), mRNA. /FEA=mRNA /GEN=RALBP1 /PROD=ralA binding protein 1 /DB_XREF=gi:5803144 /UG=Hs.75447 ralA binding protein 1 /FL=gb:NM_006788.1 gb:L42542.1" NM_006788 ralA binding protein 1 RALBP1 10928 NM_006788 /// XM_006722295 /// XM_006722296 0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from physical interaction /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay "0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016887 // ATPase activity // inferred from direct assay /// 0017160 // Ral GTPase binding // inferred from physical interaction /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0043492 // ATPase activity, coupled to movement of substances // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from physical interaction" 202846_s_at NM_002642 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002642.1 /DEF=Homo sapiens phosphatidylinositol glycan, class C (PIGC), mRNA. /FEA=mRNA /GEN=PIGC /PROD=phosphatidylinositol glycan, class C /DB_XREF=gi:4505794 /UG=Hs.75790 phosphatidylinositol glycan, class C /FL=gb:D85418.1 gb:NM_002642.1" NM_002642 "phosphatidylinositol glycan anchor biosynthesis, class C" PIGC 5279 NM_002642 /// NM_153747 /// XM_006711383 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // traceable author statement /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0003824 // catalytic activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from electronic annotation" 202847_at NM_004563 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004563.1 /DEF=Homo sapiens phosphoenolpyruvate carboxykinase 2 (mitochondrial) (PCK2), mRNA. /FEA=mRNA /GEN=PCK2 /PROD=phosphoenolpyruvate carboxykinase 2(mitochondrial) /DB_XREF=gi:4758885 /UG=Hs.75812 phosphoenolpyruvate carboxykinase 2 (mitochondrial) /FL=gb:BC001454.1 gb:NM_004563.1" NM_004563 phosphoenolpyruvate carboxykinase 2 (mitochondrial) PCK2 5106 NM_001018073 /// NM_001291556 /// NM_004563 /// XM_005267726 /// XM_006720157 /// XM_006720158 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006094 // gluconeogenesis // traceable author statement /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006116 // NADH oxidation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004611 // phosphoenolpyruvate carboxykinase activity // traceable author statement /// 0004613 // phosphoenolpyruvate carboxykinase (GTP) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202848_s_at BG423052 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG423052 /FEA=EST /DB_XREF=gi:13329558 /DB_XREF=est:602450255F1 /CLONE=IMAGE:4588980 /UG=Hs.76297 G protein-coupled receptor kinase 6 /FL=gb:L16862.1 gb:NM_002082.1 BG423052 G protein-coupled receptor kinase 6 GRK6 2870 NM_001004105 /// NM_001004106 /// NM_002082 /// XM_006714858 /// XM_006714859 /// XM_006714860 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202849_x_at NM_002082 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002082.1 /DEF=Homo sapiens G protein-coupled receptor kinase 6 (GPRK6), mRNA. /FEA=mRNA /GEN=GPRK6 /PROD=G protein-coupled receptor kinase 6 /DB_XREF=gi:4504100 /UG=Hs.76297 G protein-coupled receptor kinase 6 /FL=gb:L16862.1 gb:NM_002082.1" NM_002082 G protein-coupled receptor kinase 6 GRK6 2870 NM_001004105 /// NM_001004106 /// NM_002082 /// XM_006714858 /// XM_006714859 /// XM_006714860 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202850_at NM_002858 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002858.2 /DEF=Homo sapiens ATP-binding cassette, sub-family D (ALD), member 3 (ABCD3), mRNA. /FEA=mRNA /GEN=ABCD3 /PROD=ATP-binding cassette, sub-family D, member 3 /DB_XREF=gi:10947125 /UG=Hs.76781 ATP-binding cassette, sub-family D (ALD), member 3 /FL=gb:NM_002858.2 gb:M81182.1" NM_002858 "ATP-binding cassette, sub-family D (ALD), member 3" ABCD3 5825 NM_001122674 /// NM_002858 /// XM_005271088 /// XM_005271089 /// XM_006710802 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from direct assay /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0042760 // very long-chain fatty acid catabolic process // inferred from genetic interaction /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay" 202851_at AL136715 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:AL136715.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566A0646 (from clone DKFZp566A0646); complete cds. /FEA=mRNA /GEN=DKFZp566A0646 /PROD=hypothetical protein /DB_XREF=gi:12052948 /UG=Hs.77703 hypothetical protein FLJ11506 /FL=gb:AL136715.1 gb:NM_024666.1 AL136715 alpha- and gamma-adaptin binding protein AAGAB 79719 NM_001271885 /// NM_001271886 /// NM_024666 /// XM_005254664 /// XM_006720683 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 202852_s_at NM_024666 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024666.1 /DEF=Homo sapiens hypothetical protein FLJ11506 (FLJ11506), mRNA. /FEA=mRNA /GEN=FLJ11506 /PROD=hypothetical protein FLJ11506 /DB_XREF=gi:13375923 /UG=Hs.77703 hypothetical protein FLJ11506 /FL=gb:AL136715.1 gb:NM_024666.1" NM_024666 alpha- and gamma-adaptin binding protein AAGAB 79719 NM_001271885 /// NM_001271886 /// NM_024666 /// XM_005254664 /// XM_006720683 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 202853_s_at NM_002958 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002958.1 /DEF=Homo sapiens RYK receptor-like tyrosine kinase (RYK), mRNA. /FEA=mRNA /GEN=RYK /PROD=RYK receptor-like tyrosine kinase precursor /DB_XREF=gi:11863158 /UG=Hs.79350 RYK receptor-like tyrosine kinase /FL=gb:NM_002958.1" NM_002958 receptor-like tyrosine kinase RYK 6259 NM_001005861 /// NM_002958 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0022038 // corpus callosum development // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0071679 // commissural neuron axon guidance // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // non-traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from direct assay /// 0005109 // frizzled binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from electronic annotation /// 0042813 // Wnt-activated receptor activity // inferred from electronic annotation" 202854_at NM_000194 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000194.1 /DEF=Homo sapiens hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) (HPRT1), mRNA. /FEA=mRNA /GEN=HPRT1 /PROD=hypoxanthine phosphoribosyltransferase 1 /DB_XREF=gi:4504482 /UG=Hs.82314 hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) /FL=gb:BC000578.1 gb:M31642.1 gb:NM_000194.1" NM_000194 hypoxanthine phosphoribosyltransferase 1 HPRT1 3251 NM_000194 0001975 // response to amphetamine // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from mutant phenotype /// 0006166 // purine ribonucleoside salvage // inferred from mutant phenotype /// 0006168 // adenine salvage // not recorded /// 0006178 // guanine salvage // inferred from direct assay /// 0007610 // behavior // inferred from mutant phenotype /// 0007625 // grooming behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0021756 // striatum development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0032263 // GMP salvage // not recorded /// 0032264 // IMP salvage // not recorded /// 0032264 // IMP salvage // inferred from electronic annotation /// 0042417 // dopamine metabolic process // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0043103 // hypoxanthine salvage // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045964 // positive regulation of dopamine metabolic process // inferred from mutant phenotype /// 0046038 // GMP catabolic process // inferred from direct assay /// 0046040 // IMP metabolic process // inferred from direct assay /// 0046083 // adenine metabolic process // inferred from electronic annotation /// 0046100 // hypoxanthine metabolic process // inferred from mutant phenotype /// 0046651 // lymphocyte proliferation // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004422 // hypoxanthine phosphoribosyltransferase activity // not recorded /// 0004422 // hypoxanthine phosphoribosyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052657 // guanine phosphoribosyltransferase activity // inferred from direct assay" 202855_s_at AL513917 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL513917 /FEA=EST /DB_XREF=gi:12777411 /DB_XREF=est:AL513917 /CLONE=CL0BA006ZD09 (3 prime) /UG=Hs.85838 solute carrier family 16 (monocarboxylic acid transporters), member 3 /FL=gb:U81800.1 gb:NM_004207.1" AL513917 "microRNA 6787 /// solute carrier family 16 (monocarboxylate transporter), member 3" MIR6787 /// SLC16A3 9123 /// 102465472 NM_001042422 /// NM_001042423 /// NM_001206950 /// NM_001206951 /// NM_001206952 /// NM_004207 /// NR_106845 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202856_s_at NM_004207 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004207.1 /DEF=Homo sapiens solute carrier family 16 (monocarboxylic acid transporters), member 3 (SLC16A3), mRNA. /FEA=mRNA /GEN=SLC16A3 /PROD=solute carrier family 16 (monocarboxylic acidtransporters), member 3 /DB_XREF=gi:4759111 /UG=Hs.85838 solute carrier family 16 (monocarboxylic acid transporters), member 3 /FL=gb:U81800.1 gb:NM_004207.1" NM_004207 "microRNA 6787 /// solute carrier family 16 (monocarboxylate transporter), member 3" MIR6787 /// SLC16A3 9123 /// 102465472 NM_001042422 /// NM_001042423 /// NM_001206950 /// NM_001206951 /// NM_001206952 /// NM_004207 /// NR_106845 0006090 // pyruvate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015711 // organic anion transport // inferred from electronic annotation /// 0015718 // monocarboxylic acid transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0008028 // monocarboxylic acid transmembrane transporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation /// 0015355 // secondary active monocarboxylate transmembrane transporter activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202857_at NM_014255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014255.1 /DEF=Homo sapiens transmembrane protein 4 (TMEM4), mRNA. /FEA=mRNA /GEN=TMEM4 /PROD=transmembrane protein 4 /DB_XREF=gi:7657175 /UG=Hs.8752 transmembrane protein 4 /FL=gb:AB015631.1 gb:NM_014255.1" NM_014255 canopy FGF signaling regulator 2 CNPY2 10330 NM_001190991 /// NM_014255 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010988 // regulation of low-density lipoprotein particle clearance // inferred from sequence or structural similarity /// 0045716 // positive regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement 0005515 // protein binding // inferred from physical interaction 202858_at NM_006758 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006758.1 /DEF=Homo sapiens U2(RNU2) small nuclear RNA auxillary factor 1 (non-standard symbol) (U2AF1), mRNA. /FEA=mRNA /GEN=U2AF1 /PROD=U2 small nuclear RNA auxillary factor 1 /DB_XREF=gi:5803206 /UG=Hs.59271 U2(RNU2) small nuclear RNA auxillary factor 1 (non-standard symbol) /FL=gb:BC001177.1 gb:BC001923.1 gb:M96982.1 gb:NM_006758.1" NM_006758 U2 small nuclear RNA auxiliary factor 1 U2AF1 7307 NM_001025203 /// NM_001025204 /// NM_006758 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // traceable author statement /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050733 // RS domain binding // inferred from electronic annotation 202859_x_at NM_000584 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000584.1 /DEF=Homo sapiens interleukin 8 (IL8), mRNA. /FEA=mRNA /GEN=IL8 /PROD=interleukin 8 /DB_XREF=gi:10834977 /UG=Hs.624 interleukin 8 /FL=gb:NM_000584.1 gb:M17017.1 gb:M26383.1" NM_000584 chemokine (C-X-C motif) ligand 8 CXCL8 3576 NM_000584 0001525 // angiogenesis // traceable author statement /// 0002237 // response to molecule of bacterial origin // inferred from direct assay /// 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019722 // calcium-mediated signaling // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030593 // neutrophil chemotaxis // inferred from genetic interaction /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031623 // receptor internalization // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042119 // neutrophil activation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from expression pattern /// 0045091 // regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0048566 // embryonic digestive tract development // inferred from expression pattern /// 0050930 // induction of positive chemotaxis // inferred from genetic interaction /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0090023 // positive regulation of neutrophil chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // inferred from electronic annotation /// 0005153 // interleukin-8 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // traceable author statement 202860_at NM_014856 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014856.1 /DEF=Homo sapiens KIAA0476 gene product (KIAA0476), mRNA. /FEA=mRNA /GEN=KIAA0476 /PROD=KIAA0476 gene product /DB_XREF=gi:7662151 /UG=Hs.6684 KIAA0476 gene product /FL=gb:AB007945.1 gb:NM_014856.1" NM_014856 DENN/MADD domain containing 4B DENND4B 9909 NM_014856 /// XM_005245678 /// XM_005245679 /// XM_006711690 /// XM_006711691 /// XR_426806 0032313 // regulation of Rab GTPase activity // inferred from direct assay /// 0032483 // regulation of Rab protein signal transduction // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0017112 // Rab guanyl-nucleotide exchange factor activity // inferred from direct assay 202861_at NM_002616 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002616.1 /DEF=Homo sapiens period (Drosophila) homolog 1 (PER1), mRNA. /FEA=mRNA /GEN=PER1 /PROD=period 1 /DB_XREF=gi:4505712 /UG=Hs.68398 period (Drosophila) homolog 1 /FL=gb:AF022991.1 gb:AB002107.1 gb:NM_002616.1" NM_002616 microRNA 6883 /// period circadian clock 1 MIR6883 /// PER1 5187 /// 102465532 NM_002616 /// NR_106943 /// XM_005256689 /// XM_005256690 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from expression pattern /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009649 // entrainment of circadian clock // traceable author statement /// 0010608 // posttranscriptional regulation of gene expression // inferred from sequence or structural similarity /// 0032922 // circadian regulation of gene expression // inferred from direct assay /// 0042634 // regulation of hair cycle // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043153 // entrainment of circadian clock by photoperiod // inferred from sequence or structural similarity /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046329 // negative regulation of JNK cascade // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0070932 // histone H3 deacetylation // inferred from sequence or structural similarity /// 0097167 // circadian regulation of translation // inferred from sequence or structural similarity /// 1900015 // regulation of cytokine production involved in inflammatory response // inferred from sequence or structural similarity /// 1900744 // regulation of p38MAPK cascade // inferred from sequence or structural similarity /// 2000323 // negative regulation of glucocorticoid receptor signaling pathway // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from electronic annotation /// 0000988 // protein binding transcription factor activity // inferred from sequence or structural similarity /// 0000989 // transcription factor binding transcription factor activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0070888 // E-box binding // inferred from direct assay 202862_at NM_000137 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000137.1 /DEF=Homo sapiens fumarylacetoacetate (FAH), mRNA. /FEA=mRNA /GEN=FAH /PROD=fumarylacetoacetase /DB_XREF=gi:4557586 /UG=Hs.73875 fumarylacetoacetate /FL=gb:BC002527.1 gb:M55150.1 gb:NM_000137.1" NM_000137 fumarylacetoacetate hydrolase (fumarylacetoacetase) FAH 2184 NM_000137 0006527 // arginine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009072 // aromatic amino acid family metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004334 // fumarylacetoacetase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202863_at NM_003113 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003113.1 /DEF=Homo sapiens nuclear antigen Sp100 (SP100), mRNA. /FEA=mRNA /GEN=SP100 /PROD=nuclear antigen Sp100 /DB_XREF=gi:4507164 /UG=Hs.77617 nuclear antigen Sp100 /FL=gb:M60618.1 gb:NM_003113.1" NM_003113 SP100 nuclear antigen SP100 6672 NM_001080391 /// NM_001206701 /// NM_001206702 /// NM_001206703 /// NM_001206704 /// NM_003113 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034340 // response to type I interferon // inferred from direct assay /// 0034340 // response to type I interferon // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // inferred by curator /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred by curator /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902044 // regulation of Fas signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 202864_s_at NM_003113 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003113.1 /DEF=Homo sapiens nuclear antigen Sp100 (SP100), mRNA. /FEA=mRNA /GEN=SP100 /PROD=nuclear antigen Sp100 /DB_XREF=gi:4507164 /UG=Hs.77617 nuclear antigen Sp100 /FL=gb:M60618.1 gb:NM_003113.1" NM_003113 SP100 nuclear antigen SP100 6672 NM_001080391 /// NM_001206701 /// NM_001206702 /// NM_001206703 /// NM_001206704 /// NM_003113 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032526 // response to retinoic acid // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0034340 // response to type I interferon // inferred from direct assay /// 0034340 // response to type I interferon // inferred from mutant phenotype /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from mutant phenotype /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048384 // retinoic acid receptor signaling pathway // inferred by curator /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // inferred by curator /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred by curator /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 1902044 // regulation of Fas signaling pathway // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070087 // chromo shadow domain binding // inferred from physical interaction 202865_at AI695173 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI695173 /FEA=EST /DB_XREF=gi:4983073 /DB_XREF=est:we47h05.x1 /CLONE=IMAGE:2344281 /UG=Hs.7960 DnaJ (Hsp40) homolog, subfamily B, member 12 /FL=gb:NM_017626.1" AI695173 "DnaJ (Hsp40) homolog, subfamily B, member 12" DNAJB12 54788 NM_001002762 /// NM_017626 /// XM_005269931 /// XM_005269932 /// XR_246094 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202866_at BG283782 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG283782 /FEA=EST /DB_XREF=gi:13034069 /DB_XREF=est:602408085F1 /CLONE=IMAGE:4520181 /UG=Hs.7960 DnaJ (Hsp40) homolog, subfamily B, member 12 /FL=gb:NM_017626.1" BG283782 "DnaJ (Hsp40) homolog, subfamily B, member 12" DNAJB12 54788 NM_001002762 /// NM_017626 /// XM_005269931 /// XM_005269932 /// XR_246094 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202867_s_at NM_017626 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017626.1 /DEF=Homo sapiens hypothetical protein FLJ20027 (FLJ20027), mRNA. /FEA=mRNA /GEN=FLJ20027 /PROD=hypothetical protein FLJ20027 /DB_XREF=gi:8923029 /UG=Hs.7960 DnaJ (Hsp40) homolog, subfamily B, member 12 /FL=gb:NM_017626.1" NM_017626 "DnaJ (Hsp40) homolog, subfamily B, member 12" DNAJB12 54788 NM_001002762 /// NM_017626 /// XM_005269931 /// XM_005269932 /// XR_246094 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 202868_s_at NM_006627 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006627.1 /DEF=Homo sapiens POP4 (processing of precursor , S. cerevisiae) homolog (POP4), mRNA. /FEA=mRNA /GEN=POP4 /PROD=POP4 (processing of precursor , S. cerevisiae)homolog /DB_XREF=gi:5729985 /UG=Hs.82238 POP4 (processing of precursor , S. cerevisiae) homolog /FL=gb:BC004438.1 gb:AF001176.2 gb:NM_006627.1" NM_006627 "processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)" POP4 10775 NM_006627 /// NR_027368 "0006364 // rRNA processing // inferred from electronic annotation /// 0006379 // mRNA cleavage // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement" 0000172 // ribonuclease MRP complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005655 // nucleolar ribonuclease P complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0030677 // ribonuclease P complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 202869_at NM_016816 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016816.1 /DEF=Homo sapiens 2,5-oligoadenylate synthetase 1 (40-46 kD) (OAS1), transcript variant E18, mRNA. /FEA=mRNA /GEN=OAS1 /PROD=2,5-oligoadenylate synthetase 1, isoform E18 /DB_XREF=gi:8051620 /UG=Hs.82396 2,5-oligoadenylate synthetase 1 (40-46 kD) /FL=gb:NM_016816.1" NM_016816 "2'-5'-oligoadenylate synthetase 1, 40/46kDa" OAS1 4938 NM_001032409 /// NM_002534 /// NM_016816 /// XM_006719434 0002376 // immune system process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from mutant phenotype /// 0006164 // purine nucleotide biosynthetic process // inferred from direct assay /// 0006955 // immune response // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0035457 // cellular response to interferon-alpha // inferred from direct assay /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060700 // regulation of ribonuclease activity // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001730 // 2'-5'-oligoadenylate synthetase activity // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202870_s_at NM_001255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001255.1 /DEF=Homo sapiens CDC20 (cell division cycle 20, S. cerevisiae, homolog) (CDC20), mRNA. /FEA=mRNA /GEN=CDC20 /PROD=cell division cycle 20 /DB_XREF=gi:4557436 /UG=Hs.82906 CDC20 (cell division cycle 20, S. cerevisiae, homolog) /FL=gb:BC001088.1 gb:AF099644.1 gb:NM_001255.1 gb:U05340.1" NM_001255 cell division cycle 20 CDC20 991 NM_001255 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031915 // positive regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0050773 // regulation of dendrite development // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // inferred from direct assay /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 202871_at NM_004295 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004295.1 /DEF=Homo sapiens TNF receptor-associated factor 4 (TRAF4), mRNA. /FEA=mRNA /GEN=TRAF4 /PROD=TNF receptor-associated factor 4 /DB_XREF=gi:4759251 /UG=Hs.8375 TNF receptor-associated factor 4 /FL=gb:BC001769.1 gb:NM_004295.1" NM_004295 TNF receptor-associated factor 4 TRAF4 9618 NM_004295 /// NM_145751 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030323 // respiratory tube development // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0090073 // positive regulation of protein homodimerization activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 202872_at AW024925 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW024925 /FEA=EST /DB_XREF=gi:5878455 /DB_XREF=est:wu92g09.x1 /CLONE=IMAGE:2527552 /UG=Hs.86905 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD /FL=gb:NM_001695.1" AW024925 "ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1" ATP6V1C1 528 NM_001007254 /// NM_001695 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 202873_at BF034973 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF034973 /FEA=EST /DB_XREF=gi:10742685 /DB_XREF=est:601459039F1 /CLONE=IMAGE:3862832 /UG=Hs.86905 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD /FL=gb:NM_001695.1" BF034973 "ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1" ATP6V1C1 528 NM_001007254 /// NM_001695 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 202874_s_at NM_001695 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001695.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD (ATP6C), mRNA. /FEA=mRNA /GEN=ATP6C /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 42kD /DB_XREF=gi:4502314 /UG=Hs.86905 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD /FL=gb:NM_001695.1" NM_001695 "ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1" ATP6V1C1 528 NM_001007254 /// NM_001695 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016469 // proton-transporting two-sector ATPase complex // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" "0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement" 202875_s_at BE397715 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE397715 /FEA=EST /DB_XREF=gi:9343080 /DB_XREF=est:601289842F1 /CLONE=IMAGE:3620290 /UG=Hs.93728 pre-B-cell leukemia transcription factor 2 /FL=gb:NM_002586.1 BE397715 pre-B-cell leukemia homeobox 2 PBX2 5089 NM_002586 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202876_s_at NM_002586 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002586.1 /DEF=Homo sapiens pre-B-cell leukemia transcription factor 2 (PBX2), mRNA. /FEA=mRNA /GEN=PBX2 /PROD=pre-B-cell leukemia transcription factor 2 /DB_XREF=gi:4505624 /UG=Hs.93728 pre-B-cell leukemia transcription factor 2 /FL=gb:NM_002586.1" NM_002586 pre-B-cell leukemia homeobox 2 PBX2 5089 NM_002586 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202877_s_at W72082 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:W72082 /FEA=EST /DB_XREF=gi:1382588 /DB_XREF=est:zd70c06.s1 /CLONE=IMAGE:345994 /UG=Hs.97199 complement component C1q receptor /FL=gb:NM_012072.2 gb:U94333.1 W72082 CD93 molecule CD93 22918 NM_012072 0006909 // phagocytosis // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042116 // macrophage activation // non-traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0001849 // complement component C1q binding // inferred from direct assay /// 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 202878_s_at NM_012072 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012072.2 /DEF=Homo sapiens complement component C1q receptor (C1QR), mRNA. /FEA=mRNA /GEN=C1QR /PROD=complement component C1q receptor /DB_XREF=gi:11496985 /UG=Hs.97199 complement component C1q receptor /FL=gb:NM_012072.2 gb:U94333.1" NM_012072 CD93 molecule CD93 22918 NM_012072 0006909 // phagocytosis // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042116 // macrophage activation // non-traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation 0001849 // complement component C1q binding // inferred from direct assay /// 0004872 // receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 202879_s_at AI798823 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI798823 /FEA=EST /DB_XREF=gi:5364295 /DB_XREF=est:we93b05.x1 /CLONE=IMAGE:2348625 /UG=Hs.1050 pleckstrin homology, Sec7 and coiledcoil domains 1(cytohesin 1) /FL=gb:M85169.1 gb:NM_004762.1 gb:NM_017456.1" AI798823 cytohesin 1 CYTH1 9267 NM_001292018 /// NM_001292019 /// NM_004762 /// NM_017456 /// XM_006722180 /// XM_006722181 /// XM_006722182 /// XM_006722183 /// XM_006722184 /// XM_006722185 0016192 // vesicle-mediated transport // not recorded /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 202880_s_at NM_004762 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004762.1 /DEF=Homo sapiens pleckstrin homology, Sec7 and coiledcoil domains 1(cytohesin 1) (PSCD1), transcript variant 1, mRNA. /FEA=mRNA /GEN=PSCD1 /PROD=cytohesin 1, isoform 1 /DB_XREF=gi:4758963 /UG=Hs.1050 pleckstrin homology, Sec7 and coiledcoil domains 1(cytohesin 1) /FL=gb:M85169.1 gb:NM_004762.1 gb:NM_017456.1" NM_004762 cytohesin 1 CYTH1 9267 NM_001292018 /// NM_001292019 /// NM_004762 /// NM_017456 /// XM_006722180 /// XM_006722181 /// XM_006722182 /// XM_006722183 /// XM_006722184 /// XM_006722185 0016192 // vesicle-mediated transport // not recorded /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 202881_x_at AF172066 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF172066.2 /DEF=Homo sapiens retinoic acid repressible protein (RARG-1) mRNA, complete cds. /FEA=mRNA /GEN=RARG-1 /PROD=retinoic acid repressible protein /DB_XREF=gi:13559882 /UG=Hs.106346 retinoic acid repressible protein /FL=gb:AF172066.2 gb:NM_016167.2" AF172066 202882_x_at NM_016167 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016167.2 /DEF=Homo sapiens retinoic acid repressible protein (RARG-1), mRNA. /FEA=mRNA /GEN=RARG-1 /PROD=retinoic acid repressible protein /DB_XREF=gi:13569842 /UG=Hs.106346 retinoic acid repressible protein /FL=gb:AF172066.2 gb:NM_016167.2" NM_016167 "nucleolar protein 7, 27kDa" NOL7 51406 NM_016167 /// XM_005249173 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 202883_s_at T79584 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:T79584 /FEA=EST /DB_XREF=gi:698093 /DB_XREF=est:yd71a11.s1 /CLONE=IMAGE:113660 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1" T79584 "protein phosphatase 2, regulatory subunit A, beta" PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202884_s_at NM_002716 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002716.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform (PPP2R1B), mRNA. /FEA=mRNA /GEN=PPP2R1B /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit A (PR 65), beta isoform /DB_XREF=gi:11386166 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1" NM_002716 "protein phosphatase 2, regulatory subunit A, beta" PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202885_s_at AF163473 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF163473.1 /DEF=Homo sapiens protein phosphatase 2A regulatory subunit A beta isoform (PPP2R1B) mRNA, complete cds. /FEA=mRNA /GEN=PPP2R1B /PROD=protein phosphatase 2A regulatory subunit A betaisoform /DB_XREF=gi:11692008 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1" AF163473 "protein phosphatase 2, regulatory subunit A, beta" PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202886_s_at M65254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M65254.1 /DEF=Protein phosphatase 2A 65 kDa regulatory subunit-beta mRNA, complete cds. /FEA=mRNA /GEN=SNRPEP1 /PROD=protein phosphatase-2A regulatory subunit-beta /DB_XREF=gi:189429 /UG=Hs.108705 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform /FL=gb:NM_002716.1 gb:AF163473.1 gb:M65254.1 gb:AF087438.1" M65254 "protein phosphatase 2, regulatory subunit A, beta" PPP2R1B 5519 NM_001177562 /// NM_001177563 /// NM_002716 /// NM_181699 /// NM_181700 /// XM_006718867 /// XM_006718868 /// XM_006718869 /// XM_006718870 /// XM_006718871 /// XM_006718872 0060561 // apoptotic process involved in morphogenesis // inferred from mutant phenotype /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype 0045121 // membrane raft // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202887_s_at NM_019058 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019058.1 /DEF=Homo sapiens hypothetical protein (FLJ20500), mRNA. /FEA=mRNA /GEN=FLJ20500 /PROD=hypothetical protein /DB_XREF=gi:9506686 /UG=Hs.111244 hypothetical protein /FL=gb:AL136668.1 gb:NM_019058.1" NM_019058 DNA-damage-inducible transcript 4 DDIT4 54541 NM_019058 0001666 // response to hypoxia // inferred from direct assay /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from sequence or structural similarity /// 0008283 // cell proliferation // inferred from sequence or structural similarity /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from sequence or structural similarity /// 0043241 // protein complex disassembly // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 1901216 // positive regulation of neuron death // inferred from sequence or structural similarity /// 1902532 // negative regulation of intracellular signal transduction // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0071889 // 14-3-3 protein binding // inferred from electronic annotation 202888_s_at NM_001150 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001150.1 /DEF=Homo sapiens alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) (ANPEP), mRNA. /FEA=mRNA /GEN=ANPEP /PROD=membrane alanine aminopeptidase precursor /DB_XREF=gi:4502094 /UG=Hs.1239 alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) /FL=gb:M22324.1 gb:NM_001150.1" NM_001150 alanyl (membrane) aminopeptidase ANPEP 290 NM_001150 /// XM_005254892 0001525 // angiogenesis // inferred from electronic annotation /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202889_x_at T62571 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:T62571 /FEA=EST /DB_XREF=gi:666228 /DB_XREF=est:yc04h01.s1 /CLONE=IMAGE:79729 /UG=Hs.146388 microtubule-associated protein 7 /FL=gb:NM_003980.1 T62571 microtubule-associated protein 7 MAP7 9053 NM_001198608 /// NM_001198609 /// NM_001198611 /// NM_001198614 /// NM_001198615 /// NM_001198616 /// NM_001198617 /// NM_001198618 /// NM_001198619 /// NM_003980 /// XM_005267209 /// XM_006715598 /// XM_006715599 /// XM_006715600 /// XM_006715601 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from sequence or structural similarity /// 0006997 // nucleus organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202890_at AW242297 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW242297 /FEA=EST /DB_XREF=gi:6576051 /DB_XREF=est:xm96b11.x1 /CLONE=IMAGE:2692029 /UG=Hs.146388 microtubule-associated protein 7 /FL=gb:NM_003980.1 AW242297 microtubule-associated protein 7 MAP7 9053 NM_001198608 /// NM_001198609 /// NM_001198611 /// NM_001198614 /// NM_001198615 /// NM_001198616 /// NM_001198617 /// NM_001198618 /// NM_001198619 /// NM_003980 /// XM_005267209 /// XM_006715598 /// XM_006715599 /// XM_006715600 /// XM_006715601 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001578 // microtubule bundle formation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from sequence or structural similarity /// 0006997 // nucleus organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005198 // structural molecule activity // traceable author statement 202891_at NM_005600 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005600.1 /DEF=Homo sapiens nitrilase 1 (NIT1), mRNA. /FEA=mRNA /GEN=NIT1 /PROD=nitrilase 1 /DB_XREF=gi:5031946 /UG=Hs.146406 nitrilase 1 /FL=gb:AF069987.1 gb:NM_005600.1" NM_005600 nitrilase 1 NIT1 4817 NM_001185092 /// NM_001185093 /// NM_001185094 /// NM_005600 /// XM_005245214 /// XM_005245215 /// XM_005245216 /// XM_006711341 0006807 // nitrogen compound metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000257 // nitrilase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation" 202892_at NM_004661 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004661.1 /DEF=Homo sapiens CDC23 (cell division cycle 23, yeast, homolog) (CDC23), mRNA. /FEA=mRNA /GEN=CDC23 /PROD=cell division cycle 23, yeast homolog; CDC23 /DB_XREF=gi:4757947 /UG=Hs.153546 CDC23 (cell division cycle 23, yeast, homolog) /FL=gb:AF053977.1 gb:AB011472.1 gb:NM_004661.1 gb:AF191341.1" NM_004661 cell division cycle 23 CDC23 8697 NM_004661 0000080 // mitotic G1 phase // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0007049 // cell cycle // traceable author statement /// 0007067 // mitotic nuclear division // inferred from direct assay /// 0007080 // mitotic metaphase plate congression // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0007096 // regulation of exit from mitosis // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 202893_at NM_006377 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006377.1 /DEF=Homo sapiens UNC13 (C. elegans)-like (UNC13), mRNA. /FEA=mRNA /GEN=UNC13 /PROD=UNC13 (C. elegans)-like /DB_XREF=gi:5454147 /UG=Hs.155001 UNC13 (C. elegans)-like /FL=gb:AF020202.1 gb:NM_006377.1" NM_006377 unc-13 homolog B (C. elegans) UNC13B 10497 NM_006377 /// XM_006716716 "0006887 // exocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0016081 // synaptic vesicle docking involved in exocytosis // inferred from electronic annotation /// 0016082 // synaptic vesicle priming // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation" 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019992 // diacylglycerol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202894_at NM_004444 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:NM_004444.1 /DEF=Homo sapiens EphB4 (EPHB4) mRNA. /FEA=mRNA /GEN=HTK /PROD=EphB4 /DB_XREF=gi:4758289 /UG=Hs.155227 EphB4 /FL=gb:NM_004444.1 gb:U07695.1 NM_004444 EPH receptor B4 EPHB4 2050 NM_004444 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005003 // ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 202895_s_at D86043 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D86043.1 /DEF=Homo sapiens mRNA for SHPS-1, complete cds. /FEA=mRNA /PROD=SHPS-1 /DB_XREF=gi:1864010 /UG=Hs.156114 protein tyrosine phosphatase, non-receptor type substrate 1 /FL=gb:D86043.1 gb:NM_004648.1 gb:AB023430.1" D86043 signal-regulatory protein alpha SIRPA 140885 NM_001040022 /// NM_001040023 /// NM_080792 /// XM_005260669 /// XM_005260670 /// XM_006723545 /// XM_006723546 /// XM_006723547 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 202896_s_at NM_004648 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004648.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type substrate 1 (PTPNS1), mRNA. /FEA=mRNA /GEN=PTPNS1 /PROD=protein tyrosine phosphatase, non-receptor typesubstrate 1 /DB_XREF=gi:4758977 /UG=Hs.156114 protein tyrosine phosphatase, non-receptor type substrate 1 /FL=gb:D86043.1 gb:NM_004648.1 gb:AB023430.1" NM_004648 signal-regulatory protein alpha SIRPA 140885 NM_001040022 /// NM_001040023 /// NM_080792 /// XM_005260669 /// XM_005260670 /// XM_006723545 /// XM_006723546 /// XM_006723547 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 202897_at AB023430 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB023430.1 /DEF=Homo sapiens Bit mRNA, complete cds. /FEA=mRNA /GEN=Bit /DB_XREF=gi:6518912 /UG=Hs.156114 protein tyrosine phosphatase, non-receptor type substrate 1 /FL=gb:D86043.1 gb:NM_004648.1 gb:AB023430.1" AB023430 signal-regulatory protein alpha SIRPA 140885 NM_001040022 /// NM_001040023 /// NM_080792 /// XM_005260669 /// XM_005260670 /// XM_006723545 /// XM_006723546 /// XM_006723547 0007155 // cell adhesion // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 202898_at NM_014654 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014654.1 /DEF=Homo sapiens KIAA0468 gene product (KIAA0468), mRNA. /FEA=mRNA /GEN=KIAA0468 /PROD=KIAA0468 gene product /DB_XREF=gi:7662137 /UG=Hs.158287 KIAA0468 gene product /FL=gb:AB007937.1 gb:NM_014654.1" NM_014654 syndecan 3 SDC3 9672 NM_014654 "0001523 // retinoid metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement" 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement 0008092 // cytoskeletal protein binding // inferred from electronic annotation 202899_s_at NM_003017 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003017.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 3 (SFRS3), mRNA. /FEA=mRNA /GEN=SFRS3 /PROD=splicing factor, arginineserine-rich 3 /DB_XREF=gi:4506900 /UG=Hs.167460 splicing factor, arginineserine-rich 3 /FL=gb:L10838.1 gb:NM_003017.1" NM_003017 serine/arginine-rich splicing factor 3 SRSF3 6428 NM_003017 /// NR_036610 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 2028_s_at M96577 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "M96577 /FEATURE= /DEFINITION=HUME2F Homo sapiens (E2F-1) pRB-binding protein mRNA, complete cds" M96577 E2F transcription factor 1 E2F1 1869 NM_005225 "0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000080 // mitotic G1 phase // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0030900 // forebrain development // inferred from electronic annotation /// 0043276 // anoikis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048146 // positive regulation of fibroblast proliferation // inferred from mutant phenotype /// 0048255 // mRNA stabilization // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071930 // negative regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1990086 // lens fiber cell apoptotic process // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0035189 // Rb-E2F complex // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202900_s_at NM_002532 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002532.2 /DEF=Homo sapiens nucleoporin 88kD (NUP88), mRNA. /FEA=mRNA /GEN=NUP88 /PROD=nucleoporin 88kD /DB_XREF=gi:5729954 /UG=Hs.172108 nucleoporin 88kD /FL=gb:BC000335.1 gb:NM_002532.2" NM_002532 nucleoporin 88kDa NUP88 4927 NM_002532 /// XM_005256659 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005215 // transporter activity // traceable author statement 202901_x_at BC002642 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002642.1 /DEF=Homo sapiens, cathepsin S, clone MGC:3886, mRNA, complete cds. /FEA=mRNA /PROD=cathepsin S /DB_XREF=gi:12803614 /UG=Hs.181301 cathepsin S /FL=gb:BC002642.1 gb:M86553.1 gb:NM_004079.1 gb:M90696.1" BC002642 cathepsin S CTSS 1520 NM_001199739 /// NM_004079 "0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0034769 // basement membrane disassembly // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern" 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction 202902_s_at NM_004079 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004079.1 /DEF=Homo sapiens cathepsin S (CTSS), mRNA. /FEA=mRNA /GEN=CTSS /PROD=cathepsin S /DB_XREF=gi:4758097 /UG=Hs.181301 cathepsin S /FL=gb:BC002642.1 gb:M86553.1 gb:NM_004079.1 gb:M90696.1" NM_004079 cathepsin S CTSS 1520 NM_001199739 /// NM_004079 "0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0034769 // basement membrane disassembly // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern" 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction 202903_at AU153477 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU153477 /FEA=EST /DB_XREF=gi:11014998 /DB_XREF=est:AU153477 /CLONE=NT2RP3003272 /UG=Hs.227280 U6 snRNA-associated Sm-like protein /FL=gb:AF182291.1 gb:NM_012322.1 AU153477 "LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)" LSM5 23658 NM_001130710 /// NM_001139499 /// NM_012322 /// NR_024466 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202904_s_at NM_012322 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012322.1 /DEF=Homo sapiens U6 snRNA-associated Sm-like protein (LSM5), mRNA. /FEA=mRNA /GEN=LSM5 /PROD=U6 snRNA-associated Sm-like protein /DB_XREF=gi:6912487 /UG=Hs.227280 U6 snRNA-associated Sm-like protein /FL=gb:AF182291.1 gb:NM_012322.1" NM_012322 "LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)" LSM5 23658 NM_001130710 /// NM_001139499 /// NM_012322 /// NR_024466 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202905_x_at AI796269 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI796269 /FEA=EST /DB_XREF=gi:5361732 /DB_XREF=est:wh44g10.x1 /CLONE=IMAGE:2383650 /UG=Hs.25812 Nijmegen breakage syndrome 1 (nibrin) /FL=gb:AF058696.1 gb:AF051334.1 gb:NM_002485.2 AI796269 nibrin NBN 4683 NM_001024688 /// NM_002485 /// XM_005250923 /// XR_242390 /// XR_242391 "0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045190 // isotype switching // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation" "0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay" 0003684 // damaged DNA binding // inferred by curator /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 202906_s_at AF049895 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF049895 /DEF=Homo sapiens 8q21.3: Nibrin (NBS1), 2,4-dienoyl-CoA reductase (DECR), and calbindin 1 (CALB1) genes /FEA=mRNA_5 /DB_XREF=gi:4126312 /UG=Hs.25812 Nijmegen breakage syndrome 1 (nibrin) /FL=gb:AF058696.1 gb:AF051334.1 gb:NM_002485.2" AF049895 nibrin NBN 4683 NM_001024688 /// NM_002485 /// XM_005250923 /// XR_242390 /// XR_242391 "0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045190 // isotype switching // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation" "0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay" 0003684 // damaged DNA binding // inferred by curator /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 202907_s_at NM_002485 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002485.2 /DEF=Homo sapiens Nijmegen breakage syndrome 1 (nibrin) (NBS1), mRNA. /FEA=mRNA /GEN=NBS1 /PROD=nibrin /DB_XREF=gi:6996019 /UG=Hs.25812 Nijmegen breakage syndrome 1 (nibrin) /FL=gb:AF058696.1 gb:AF051334.1 gb:NM_002485.2" NM_002485 nibrin NBN 4683 NM_001024688 /// NM_002485 /// XM_005250923 /// XR_242390 /// XR_242391 "0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000077 // DNA damage checkpoint // inferred from direct assay /// 0000723 // telomere maintenance // inferred from mutant phenotype /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001832 // blastocyst growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from direct assay /// 0006302 // double-strand break repair // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030174 // regulation of DNA-dependent DNA replication initiation // traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032508 // DNA duplex unwinding // inferred from mutant phenotype /// 0033674 // positive regulation of kinase activity // inferred from direct assay /// 0045190 // isotype switching // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation" "0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay" 0003684 // damaged DNA binding // inferred by curator /// 0004003 // ATP-dependent DNA helicase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 202908_at NM_006005 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006005.2 /DEF=Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), mRNA. /FEA=mRNA /GEN=WFS1 /PROD=Wolfram syndrome protein /DB_XREF=gi:13376995 /UG=Hs.26077 Wolfram syndrome 1 (wolframin) /FL=gb:NM_006005.2 gb:AF084481.1" NM_006005 Wolfram syndrome 1 (wolframin) WFS1 7466 NM_001145853 /// NM_006005 0001822 // kidney development // inferred from mutant phenotype /// 0003091 // renal water homeostasis // inferred from mutant phenotype /// 0006983 // ER overload response // inferred by curator /// 0006983 // ER overload response // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022417 // protein maturation by protein folding // inferred by curator /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042048 // olfactory behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from sequence or structural similarity /// 0045927 // positive regulation of growth // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0051247 // positive regulation of protein metabolic process // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0070845 // polyubiquitinated misfolded protein transport // inferred from sequence or structural similarity /// 1902236 // negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity 0005215 // transporter activity // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0033613 // activating transcription factor binding // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 202909_at NM_014805 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014805.1 /DEF=Homo sapiens KIAA0766 gene product (KIAA0766), mRNA. /FEA=mRNA /GEN=KIAA0766 /PROD=KIAA0766 gene product /DB_XREF=gi:7662293 /UG=Hs.28020 KIAA0766 gene product /FL=gb:AF059751.1 gb:AB018309.1 gb:NM_014805.1" NM_014805 EPM2A (laforin) interacting protein 1 EPM2AIP1 9852 NM_014805 0005783 // endoplasmic reticulum // inferred from electronic annotation 202910_s_at NM_001784 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001784.1 /DEF=Homo sapiens CD97 antigen (CD97), mRNA. /FEA=mRNA /GEN=CD97 /PROD=CD97 antigen /DB_XREF=gi:4502690 /UG=Hs.3107 CD97 antigen /FL=gb:NM_001784.1" NM_001784 CD97 molecule CD97 976 NM_001025160 /// NM_001784 /// NM_078481 /// XM_005260170 /// XM_005260171 /// XM_005260172 0006928 // cellular component movement // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202911_at NM_000179 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000179.1 /DEF=Homo sapiens mutS (E. coli) homolog 6 (MSH6), mRNA. /FEA=mRNA /GEN=MSH6 /PROD=mutS (E. coli) homolog 6 /DB_XREF=gi:4504190 /UG=Hs.3248 mutS (E. coli) homolog 6 /FL=gb:U28946.1 gb:BC004246.1 gb:NM_000179.1 gb:U54777.2" NM_000179 mutS homolog 6 MSH6 2956 NM_000179 /// NM_001281492 /// NM_001281493 /// NM_001281494 /// XM_005264271 0000710 // meiotic mismatch repair // not recorded /// 0000710 // meiotic mismatch repair // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from sequence or structural similarity /// 0009411 // response to UV // not recorded /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from sequence or structural similarity /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from sequence or structural similarity /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045190 // isotype switching // not recorded /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000228 // nuclear chromosome // not recorded /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0032301 // MutSalpha complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0016887 // ATPase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032143 // single thymine insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay 202912_at NM_001124 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001124.1 /DEF=Homo sapiens adrenomedullin (ADM), mRNA. /FEA=mRNA /GEN=ADM /PROD=adrenomedullin /DB_XREF=gi:4501944 /UG=Hs.394 adrenomedullin /FL=gb:NM_001124.1 gb:D14874.1" NM_001124 adrenomedullin ADM 133 NM_001124 0001570 // vasculogenesis // inferred from direct assay /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0006171 // cAMP biosynthetic process // inferred from direct assay /// 0006701 // progesterone biosynthetic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031102 // neuron projection regeneration // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042594 // response to starvation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043116 // negative regulation of vascular permeability // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045906 // negative regulation of vasoconstriction // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation /// 0046879 // hormone secretion // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from electronic annotation /// 0060712 // spongiotrophoblast layer development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from electronic annotation /// 2001214 // positive regulation of vasculogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031700 // adrenomedullin receptor binding // inferred from electronic annotation 202913_at AI090007 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI090007 /FEA=EST /DB_XREF=gi:3429066 /DB_XREF=est:qb13h01.x1 /CLONE=IMAGE:1696177 /UG=Hs.47822 Rho guanine exchange factor (GEF) 11 /FL=gb:AB002378.1 gb:NM_014784.1 AI090007 Rho guanine nucleotide exchange factor (GEF) 11 ARHGEF11 9826 NM_014784 /// NM_198236 /// XM_005245629 /// XM_005245633 /// XM_006711659 /// XM_006711660 /// XM_006711661 /// XM_006711662 /// XM_006711663 /// XM_006711664 /// XM_006711665 "0000910 // cytokinesis // non-traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006941 // striated muscle contraction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0030010 // establishment of cell polarity // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement" 0005622 // intracellular // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 202914_s_at NM_014784 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014784.1 /DEF=Homo sapiens Rho guanine exchange factor (GEF) 11 (ARHGEF11), mRNA. /FEA=mRNA /GEN=ARHGEF11 /PROD=Rho guanine exchange factor (GEF) 11 /DB_XREF=gi:7662085 /UG=Hs.47822 Rho guanine exchange factor (GEF) 11 /FL=gb:AB002378.1 gb:NM_014784.1" NM_014784 Rho guanine nucleotide exchange factor (GEF) 11 ARHGEF11 9826 NM_014784 /// NM_198236 /// XM_005245629 /// XM_005245633 /// XM_006711659 /// XM_006711660 /// XM_006711661 /// XM_006711662 /// XM_006711663 /// XM_006711664 /// XM_006711665 "0000910 // cytokinesis // non-traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006941 // striated muscle contraction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0030010 // establishment of cell polarity // non-traceable author statement /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement" 0005622 // intracellular // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation 202915_s_at BF115776 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF115776 /FEA=EST /DB_XREF=gi:10985252 /DB_XREF=est:7n64f10.x1 /CLONE=IMAGE:3569442 /UG=Hs.5737 KIAA0475 gene product /FL=gb:AB007944.1 gb:NM_014864.1 BF115776 "family with sequence similarity 20, member B" FAM20B 9917 NM_014864 0016310 // phosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from direct assay" 202916_s_at NM_014864 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014864.1 /DEF=Homo sapiens KIAA0475 gene product (KIAA0475), mRNA. /FEA=mRNA /GEN=KIAA0475 /PROD=KIAA0475 gene product /DB_XREF=gi:7662149 /UG=Hs.5737 KIAA0475 gene product /FL=gb:AB007944.1 gb:NM_014864.1" NM_014864 "family with sequence similarity 20, member B" FAM20B 9917 NM_014864 0016310 // phosphorylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from direct assay" 202917_s_at NM_002964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002964.2 /DEF=Homo sapiens S100 calcium-binding protein A8 (calgranulin A) (S100A8), mRNA. /FEA=mRNA /GEN=S100A8 /PROD=S100 calcium-binding protein A8 /DB_XREF=gi:9845519 /UG=Hs.100000 S100 calcium-binding protein A8 (calgranulin A) /FL=gb:NM_002964.2" NM_002964 S100 calcium binding protein A8 S100A8 6279 NM_002964 0001816 // cytokine production // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002523 // leukocyte migration involved in inflammatory response // inferred from direct assay /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006914 // autophagy // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0032119 // sequestering of zinc ion // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032602 // chemokine production // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042742 // defense response to bacterium // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from direct assay /// 0050832 // defense response to fungus // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0070488 // neutrophil aggregation // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0035662 // Toll-like receptor 4 binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // traceable author statement /// 0050786 // RAGE receptor binding // traceable author statement 202918_s_at AF151853 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF151853.1 /DEF=Homo sapiens CGI-95 protein mRNA, complete cds. /FEA=mRNA /PROD=CGI-95 protein /DB_XREF=gi:4929658 /UG=Hs.107942 DKFZP564M112 protein /FL=gb:AB015441.1 gb:BC005237.1 gb:AF151853.1 gb:AL080070.1 gb:NM_015387.1" AF151853 "HSPE1-MOB4 readthrough /// MOB family member 4, phocein" HSPE1-MOB4 /// MOB4 25843 /// 100529241 NM_001100819 /// NM_001202485 /// NM_001204094 /// NM_015387 /// NM_199482 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202919_at NM_015387 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015387.1 /DEF=Homo sapiens DKFZP564M112 protein (DKFZP564M112), mRNA. /FEA=mRNA /GEN=DKFZP564M112 /PROD=DKFZP564M112 protein /DB_XREF=gi:7661623 /UG=Hs.107942 DKFZP564M112 protein /FL=gb:AB015441.1 gb:BC005237.1 gb:AF151853.1 gb:AL080070.1 gb:NM_015387.1" NM_015387 "MOB family member 4, phocein" MOB4 25843 NM_001100819 /// NM_001204094 /// NM_015387 /// NM_199482 0006457 // protein folding // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202920_at BF726212 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF726212 /FEA=EST /DB_XREF=gi:12042123 /DB_XREF=est:by03a08.y1 /CLONE=by03a08 /UG=Hs.117970 ankyrin 2, neuronal /FL=gb:NM_001148.2" BF726212 "ankyrin 2, neuronal" ANK2 287 NM_001127493 /// NM_001148 /// NM_020977 /// XM_005262942 /// XM_005262945 /// XM_005262948 /// XM_006714187 /// XM_006714188 /// XM_006714189 /// XM_006714190 /// XM_006714191 /// XM_006714192 /// XM_006714193 /// XM_006714194 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003283 // atrial septum development // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from mutant phenotype /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred by curator /// 0033292 // T-tubule organization // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from genetic interaction /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from genetic interaction /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0036371 // protein localization to T-tubule // inferred from sequence or structural similarity /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from genetic interaction /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from genetic interaction /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070972 // protein localization to endoplasmic reticulum // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from genetic interaction /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086015 // SA node cell action potential // inferred from sequence or structural similarity /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from electronic annotation /// 0086046 // membrane depolarization during SA node cell action potential // traceable author statement /// 0086066 // atrial cardiac muscle cell to AV node cell communication // inferred from sequence or structural similarity /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from sequence or structural similarity /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901019 // regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901021 // positive regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001257 // regulation of cation channel activity // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity /// 0031672 // A band // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity" 202921_s_at NM_001148 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001148.2 /DEF=Homo sapiens ankyrin 2, neuronal (ANK2), transcript variant 1, mRNA. /FEA=mRNA /GEN=ANK2 /PROD=ankyrin 2, isoform 1 /DB_XREF=gi:10947051 /UG=Hs.117970 ankyrin 2, neuronal /FL=gb:NM_001148.2" NM_001148 "ankyrin 2, neuronal" ANK2 287 NM_001127493 /// NM_001148 /// NM_020977 /// XM_005262942 /// XM_005262945 /// XM_005262948 /// XM_006714187 /// XM_006714188 /// XM_006714189 /// XM_006714190 /// XM_006714191 /// XM_006714192 /// XM_006714193 /// XM_006714194 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003283 // atrial septum development // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from mutant phenotype /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred by curator /// 0033292 // T-tubule organization // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from genetic interaction /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from genetic interaction /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0036371 // protein localization to T-tubule // inferred from sequence or structural similarity /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from genetic interaction /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from genetic interaction /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070972 // protein localization to endoplasmic reticulum // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from genetic interaction /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086015 // SA node cell action potential // inferred from sequence or structural similarity /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from electronic annotation /// 0086046 // membrane depolarization during SA node cell action potential // traceable author statement /// 0086066 // atrial cardiac muscle cell to AV node cell communication // inferred from sequence or structural similarity /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from sequence or structural similarity /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901019 // regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901021 // positive regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001257 // regulation of cation channel activity // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from sequence or structural similarity 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity /// 0031672 // A band // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity" 202922_at BF676980 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF676980 /FEA=EST /DB_XREF=gi:11950875 /DB_XREF=est:602084207F1 /CLONE=IMAGE:4248744 /UG=Hs.151393 glutamate-cysteine ligase, catalytic subunit /FL=gb:M90656.1 gb:NM_001498.1" BF676980 "glutamate-cysteine ligase, catalytic subunit" GCLC 2729 NM_001197115 /// NM_001498 "0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006534 // cysteine metabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009408 // response to heat // inferred from direct assay /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from direct assay /// 0019852 // L-ascorbic acid metabolic process // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from mutant phenotype /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051900 // regulation of mitochondrial depolarization // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0017109 // glutamate-cysteine ligase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from physical interaction 202923_s_at NM_001498 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001498.1 /DEF=Homo sapiens glutamate-cysteine ligase, catalytic subunit (GCLC), mRNA. /FEA=mRNA /GEN=GCLC /PROD=glutamate-cysteine ligase /DB_XREF=gi:4557624 /UG=Hs.151393 glutamate-cysteine ligase, catalytic subunit /FL=gb:M90656.1 gb:NM_001498.1" NM_001498 "glutamate-cysteine ligase, catalytic subunit" GCLC 2729 NM_001197115 /// NM_001498 "0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006534 // cysteine metabolic process // inferred from direct assay /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009408 // response to heat // inferred from direct assay /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from direct assay /// 0019852 // L-ascorbic acid metabolic process // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from mutant phenotype /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051900 // regulation of mitochondrial depolarization // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0017109 // glutamate-cysteine ligase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0043531 // ADP binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from physical interaction 202924_s_at AL562280 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL562280 /FEA=EST /DB_XREF=gi:12910544 /DB_XREF=est:AL562280 /CLONE=CS0DC003YF04 (3 prime) /UG=Hs.154104 pleiomorphic adenoma gene-like 2 /FL=gb:AF006005.1 gb:NM_002657.2 AL562280 pleiomorphic adenoma gene-like 2 PLAGL2 5326 NM_002657 /// XM_005260436 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0034378 // chylomicron assembly // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202925_s_at NM_002657 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002657.2 /DEF=Homo sapiens pleiomorphic adenoma gene-like 2 (PLAGL2), mRNA. /FEA=mRNA /GEN=PLAGL2 /PROD=pleiomorphic adenoma gene-like 2 /DB_XREF=gi:6031195 /UG=Hs.154104 pleiomorphic adenoma gene-like 2 /FL=gb:AF006005.1 gb:NM_002657.2" NM_002657 pleiomorphic adenoma gene-like 2 PLAGL2 5326 NM_002657 /// XM_005260436 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0034378 // chylomicron assembly // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202926_at NM_015909 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015909.1 /DEF=Homo sapiens neuroblastoma-amplified protein (LOC51594), mRNA. /FEA=mRNA /GEN=LOC51594 /PROD=neuroblastoma-amplified protein /DB_XREF=gi:7706239 /UG=Hs.15430 neuroblastoma-amplified protein /FL=gb:AF056195.1 gb:NM_015909.1" NM_015909 neuroblastoma amplified sequence NBAS 51594 NM_015909 /// NR_052013 "0000956 // nuclear-transcribed mRNA catabolic process // inferred from mutant phenotype /// 2000623 // negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype" 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 202927_at NM_006221 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006221.1 /DEF=Homo sapiens protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting 1 (PIN1), mRNA. /FEA=mRNA /GEN=PIN1 /PROD=protein (peptidyl-prolyl cistrans isomerase)NIMA-interacting 1 /DB_XREF=gi:5453897 /UG=Hs.161362 protein (peptidyl-prolyl cistrans isomerase) NIMA-interacting 1 /FL=gb:BC002899.1 gb:U49070.1 gb:NM_006221.1" NM_006221 "peptidylprolyl cis/trans isomerase, NIMA-interacting 1" PIN1 5300 NM_006221 /// NR_038422 /// NR_038830 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from genetic interaction /// 0006457 // protein folding // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007088 // regulation of mitosis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032465 // regulation of cytokinesis // inferred from genetic interaction /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from direct assay /// 0060393 // regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 2000146 // negative regulation of cell motility // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from physical interaction /// 0032794 // GTPase activating protein binding // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from direct assay /// 0050816 // phosphothreonine binding // inferred from direct assay /// 0050816 // phosphothreonine binding // inferred from physical interaction 202928_s_at NM_024165 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024165.1 /DEF=Homo sapiens PHD finger protein 1 (PHF1), transcript variant 2, mRNA. /FEA=mRNA /GEN=PHF1 /PROD=PHD finger protein 1, isoform b /DB_XREF=gi:13435396 /UG=Hs.166204 PHD finger protein 1 /FL=gb:NM_024165.1 gb:AF052205.1" NM_024165 PHD finger protein 1 PHF1 5252 NM_002636 /// NM_024165 /// NR_027692 /// XM_006715109 /// XM_006715110 /// XM_006715111 /// XM_006726097 /// XM_006726098 /// XM_006726099 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from mutant phenotype /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0035861 // site of double-strand break // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 202929_s_at NM_001355 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001355.2 /DEF=Homo sapiens D-dopachrome tautomerase (DDT), mRNA. /FEA=mRNA /GEN=DDT /PROD=D-dopachrome tautomerase /DB_XREF=gi:5453630 /UG=Hs.180015 D-dopachrome tautomerase /FL=gb:U84143.1 gb:U49785.1 gb:NM_001355.2" NM_001355 D-dopachrome tautomerase /// D-dopachrome tautomerase-like DDT /// DDTL 1652 /// 100037417 NM_001084392 /// NM_001084393 /// NM_001355 /// XM_005261299 /// XM_006725405 /// XM_006725406 0008152 // metabolic process // inferred from electronic annotation /// 0042438 // melanin biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004167 // dopachrome isomerase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0033981 // D-dopachrome decarboxylase activity // inferred from electronic annotation 202930_s_at NM_003850 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003850.1 /DEF=Homo sapiens succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2), mRNA. /FEA=mRNA /GEN=SUCLA2 /PROD=succinate-CoA ligase, ADP-forming, beta subunit /DB_XREF=gi:11321582 /UG=Hs.182217 succinate-CoA ligase, ADP-forming, beta subunit /FL=gb:NM_003850.1 gb:AB035863.1" NM_003850 "succinate-CoA ligase, ADP-forming, beta subunit" SUCLA2 8803 NM_003850 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006104 // succinyl-CoA metabolic process // traceable author statement /// 0006105 // succinate metabolic process // inferred from electronic annotation /// 0006781 // succinyl-CoA pathway // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004775 // succinate-CoA ligase (ADP-forming) activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202931_x_at NM_004305 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004305.1 /DEF=Homo sapiens bridging integrator 1 (BIN1), mRNA. /FEA=mRNA /GEN=BIN1 /PROD=bridging integrator 1 /DB_XREF=gi:4757747 /UG=Hs.193163 bridging integrator 1 /FL=gb:U68485.1 gb:NM_004305.1" NM_004305 bridging integrator 1 BIN1 274 NM_004305 /// NM_139343 /// NM_139344 /// NM_139345 /// NM_139346 /// NM_139347 /// NM_139348 /// NM_139349 /// NM_139350 /// NM_139351 /// XM_005263642 /// XM_005263643 /// XM_005263644 /// XM_005263645 /// XM_005263646 /// XM_005263647 /// XM_005263648 /// XM_006712424 /// XM_006712425 /// XM_006712426 /// XM_006712427 /// XM_006712428 /// XM_006712429 /// XM_006712430 /// XM_006712431 /// XM_006712432 /// XM_006712433 /// XM_006712434 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from mutant phenotype /// 0045807 // positive regulation of endocytosis // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from mutant phenotype /// 0060988 // lipid tube assembly // inferred from mutant phenotype /// 0071156 // regulation of cell cycle arrest // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0030424 // axon // inferred from direct assay /// 0031674 // I band // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0043196 // varicosity // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0044300 // cerebellar mossy fiber // inferred from electronic annotation /// 0060987 // lipid tube // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0048156 // tau protein binding // inferred from physical interaction /// 0051020 // GTPase binding // inferred from electronic annotation 202932_at NM_005433 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005433.1 /DEF=Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1), mRNA. /FEA=mRNA /GEN=YES1 /PROD=v-yes-1 Yamaguchi sarcoma viral oncogene homolog1 /DB_XREF=gi:4885660 /UG=Hs.194148 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 /FL=gb:NM_005433.1" NM_005433 "YES proto-oncogene 1, Src family tyrosine kinase" YES1 7525 NM_005433 /// XM_005258139 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015758 // glucose transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // not recorded /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction" 202933_s_at NM_005433 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005433.1 /DEF=Homo sapiens v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1), mRNA. /FEA=mRNA /GEN=YES1 /PROD=v-yes-1 Yamaguchi sarcoma viral oncogene homolog1 /DB_XREF=gi:4885660 /UG=Hs.194148 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 /FL=gb:NM_005433.1" NM_005433 "YES proto-oncogene 1, Src family tyrosine kinase" YES1 7525 NM_005433 /// XM_005258139 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015758 // glucose transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // not recorded /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043114 // regulation of vascular permeability // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction" 202934_at AI761561 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI761561 /FEA=EST /DB_XREF=gi:5177228 /DB_XREF=est:wi61h11.x1 /CLONE=IMAGE:2394789 /UG=Hs.198427 hexokinase 2 /FL=gb:NM_000189.1 gb:AF148513.1 AI761561 hexokinase 2 HK2 3099 NM_000189 /// XM_005264280 0001678 // cellular glucose homeostasis // not recorded /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // not recorded /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from direct assay /// 0008645 // hexose transport // traceable author statement /// 0015758 // glucose transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019318 // hexose metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0051156 // glucose 6-phosphate metabolic process // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004340 // glucokinase activity // not recorded /// 0004396 // hexokinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005536 // glucose binding // inferred from electronic annotation /// 0008865 // fructokinase activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019158 // mannokinase activity // not recorded" 202935_s_at AI382146 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI382146 /FEA=EST /DB_XREF=gi:4194927 /DB_XREF=est:te30c10.x1 /CLONE=IMAGE:2087442 /UG=Hs.2316 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) /FL=gb:NM_000346.1" AI382146 SRY (sex determining region Y)-box 9 SOX9 6662 NM_000346 "0001501 // skeletal system development // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001894 // tissue homeostasis // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002683 // negative regulation of immune system process // inferred from sequence or structural similarity /// 0003170 // heart valve development // inferred from sequence or structural similarity /// 0003179 // heart valve morphogenesis // inferred from sequence or structural similarity /// 0003188 // heart valve formation // inferred from electronic annotation /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003413 // chondrocyte differentiation involved in endochondral bone morphogenesis // inferred from mutant phenotype /// 0003415 // chondrocyte hypertrophy // inferred from sequence or structural similarity /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0008584 // male gonad development // inferred from mutant phenotype /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0019100 // male germ-line sex determination // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from sequence or structural similarity /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from expression pattern /// 0030858 // positive regulation of epithelial cell differentiation // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from direct assay /// 0032332 // positive regulation of chondrocyte differentiation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0035622 // intrahepatic bile duct development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046533 // negative regulation of photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from expression pattern /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0060008 // Sertoli cell differentiation // inferred from sequence or structural similarity /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060221 // retinal rod cell differentiation // inferred from sequence or structural similarity /// 0060350 // endochondral bone morphogenesis // inferred from electronic annotation /// 0060512 // prostate gland morphogenesis // inferred from electronic annotation /// 0060517 // epithelial cell proliferation involved in prostatic bud elongation // inferred from sequence or structural similarity /// 0060729 // intestinal epithelial structure maintenance // inferred from sequence or structural similarity /// 0060784 // regulation of cell proliferation involved in tissue homeostasis // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0061138 // morphogenesis of a branching epithelium // inferred from sequence or structural similarity /// 0070168 // negative regulation of biomineral tissue development // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0072034 // renal vesicle induction // inferred from sequence or structural similarity /// 0072170 // metanephric tubule development // inferred from electronic annotation /// 0072190 // ureter urothelium development // inferred from electronic annotation /// 0072197 // ureter morphogenesis // inferred from electronic annotation /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0090184 // positive regulation of kidney development // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from direct assay /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from electronic annotation /// 2000741 // positive regulation of mesenchymal stem cell differentiation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001158 // enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 202936_s_at NM_000346 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000346.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) (SOX9), mRNA. /FEA=mRNA /GEN=SOX9 /PROD=transcription factor SOX9 /DB_XREF=gi:4557852 /UG=Hs.2316 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) /FL=gb:NM_000346.1" NM_000346 SRY (sex determining region Y)-box 9 SOX9 6662 NM_000346 "0001501 // skeletal system development // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from sequence or structural similarity /// 0001503 // ossification // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001894 // tissue homeostasis // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0001942 // hair follicle development // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002683 // negative regulation of immune system process // inferred from sequence or structural similarity /// 0003170 // heart valve development // inferred from sequence or structural similarity /// 0003179 // heart valve morphogenesis // inferred from sequence or structural similarity /// 0003188 // heart valve formation // inferred from electronic annotation /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003413 // chondrocyte differentiation involved in endochondral bone morphogenesis // inferred from mutant phenotype /// 0003415 // chondrocyte hypertrophy // inferred from sequence or structural similarity /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from sequence or structural similarity /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern /// 0008584 // male gonad development // inferred from mutant phenotype /// 0010564 // regulation of cell cycle process // inferred from mutant phenotype /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0014032 // neural crest cell development // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0019100 // male germ-line sex determination // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from sequence or structural similarity /// 0030502 // negative regulation of bone mineralization // inferred from electronic annotation /// 0030850 // prostate gland development // inferred from expression pattern /// 0030858 // positive regulation of epithelial cell differentiation // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from direct assay /// 0032332 // positive regulation of chondrocyte differentiation // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0035622 // intrahepatic bile duct development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045662 // negative regulation of myoblast differentiation // inferred from sequence or structural similarity /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046533 // negative regulation of photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from expression pattern /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from sequence or structural similarity /// 0060008 // Sertoli cell differentiation // inferred from sequence or structural similarity /// 0060009 // Sertoli cell development // inferred from electronic annotation /// 0060018 // astrocyte fate commitment // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060221 // retinal rod cell differentiation // inferred from sequence or structural similarity /// 0060350 // endochondral bone morphogenesis // inferred from electronic annotation /// 0060512 // prostate gland morphogenesis // inferred from electronic annotation /// 0060517 // epithelial cell proliferation involved in prostatic bud elongation // inferred from sequence or structural similarity /// 0060729 // intestinal epithelial structure maintenance // inferred from sequence or structural similarity /// 0060784 // regulation of cell proliferation involved in tissue homeostasis // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0061138 // morphogenesis of a branching epithelium // inferred from sequence or structural similarity /// 0070168 // negative regulation of biomineral tissue development // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from sequence or structural similarity /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0071599 // otic vesicle development // inferred from electronic annotation /// 0072034 // renal vesicle induction // inferred from sequence or structural similarity /// 0072170 // metanephric tubule development // inferred from electronic annotation /// 0072190 // ureter urothelium development // inferred from electronic annotation /// 0072197 // ureter morphogenesis // inferred from electronic annotation /// 0072289 // metanephric nephron tubule formation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090103 // cochlea morphogenesis // inferred from sequence or structural similarity /// 0090184 // positive regulation of kidney development // inferred from sequence or structural similarity /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from direct assay /// 2000138 // positive regulation of cell proliferation involved in heart morphogenesis // inferred from electronic annotation /// 2000741 // positive regulation of mesenchymal stem cell differentiation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001158 // enhancer sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred from direct assay /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation 202937_x_at AL022316 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL022316 /DEF=Human DNA sequence from clone CTA-126B4 on chromosome 22q13.2-13.31 Contains two or three novel genes, ESTs, STSs, GSSs and a CpG Island /FEA=mRNA_3 /DB_XREF=gi:4691242 /UG=Hs.239934 CGI-96 protein /FL=gb:AF151854.1 gb:NM_015703.1" AL022316 ribosomal RNA processing 7 homolog A (S. cerevisiae) RRP7A 27341 NM_015703 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202938_x_at NM_015703 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015703.1 /DEF=Homo sapiens CGI-96 protein (CGI-96), mRNA. /FEA=mRNA /GEN=CGI-96 /PROD=CGI-96 protein /DB_XREF=gi:7661545 /UG=Hs.239934 CGI-96 protein /FL=gb:AF151854.1 gb:NM_015703.1" NM_015703 ribosomal RNA processing 7 homolog A (S. cerevisiae) /// ribosomal RNA processing 7 homolog B (S. cerevisiae) RRP7A /// RRP7B 27341 /// 91695 NM_015703 /// NR_002184 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 202939_at NM_005857 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005857.1 /DEF=Homo sapiens zinc metalloproteinase, STE24 (yeast, homolog) (ZMPSTE24), mRNA. /FEA=mRNA /GEN=ZMPSTE24 /PROD=zinc metalloproteinase, STE24 (yeast, homolog) /DB_XREF=gi:5032128 /UG=Hs.25846 zinc metalloproteinase, STE24 (yeast, homolog) /FL=gb:AB016068.1 gb:AF064867.1 gb:NM_005857.1" NM_005857 zinc metallopeptidase STE24 ZMPSTE24 10269 NM_005857 0006508 // proteolysis // traceable author statement /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0030327 // prenylated protein catabolic process // inferred from electronic annotation /// 0071586 // CAAX-box protein processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202940_at NM_014823 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014823.1 /DEF=Homo sapiens KIAA0344 gene product (KIAA0344), mRNA. /FEA=mRNA /GEN=KIAA0344 /PROD=KIAA0344 gene product /DB_XREF=gi:7662065 /UG=Hs.321444 KIAA0344 gene product /FL=gb:AB002342.1 gb:NM_014823.1" NM_014823 WNK lysine deficient protein kinase 1 WNK1 65125 NM_001184985 /// NM_014823 /// NM_018979 /// NM_213655 /// XM_005253734 /// XM_005253735 /// XM_005253736 /// XM_005253737 /// XM_005253738 /// XM_005253739 /// XM_005253740 /// XM_005253741 /// XM_005253743 /// XM_006718998 /// XM_006718999 /// XM_006719000 /// XM_006719001 /// XM_006719002 /// XM_006719003 /// XM_006719004 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0048666 // neuron development // non-traceable author statement /// 0050794 // regulation of cellular process // inferred from sequence or structural similarity /// 0090188 // negative regulation of pancreatic juice secretion // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019869 // chloride channel inhibitor activity // inferred from direct assay /// 0019902 // phosphatase binding // inferred from direct assay" 202941_at NM_021074 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021074.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD) (NDUFV2), mRNA. /FEA=mRNA /GEN=NDUFV2 /PROD=NADH dehydrogenase (ubiquinone) flavoprotein 2(24kD) /DB_XREF=gi:10835024 /UG=Hs.51299 NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD) /FL=gb:NM_021074.1 gb:BC001632.1 gb:M22538.1" NM_021074 "NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa" NDUFV2 4729 NM_021074 /// XR_243808 "0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from mutant phenotype /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0007399 // nervous system development // inferred from mutant phenotype /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045272 // plasma membrane respiratory chain complex I // not recorded /// 0070469 // respiratory chain // inferred from electronic annotation "0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation" 202942_at NM_001985 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001985.1 /DEF=Homo sapiens electron-transfer-flavoprotein, beta polypeptide (ETFB), mRNA. /FEA=mRNA /GEN=ETFB /PROD=electron-transfer-flavoprotein, betapolypeptide /DB_XREF=gi:4503608 /UG=Hs.74047 electron-transfer-flavoprotein, beta polypeptide /FL=gb:NM_001985.1" NM_001985 "electron-transfer-flavoprotein, beta polypeptide" ETFB 2109 NM_001014763 /// NM_001985 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0009055 // electron carrier activity // inferred from electronic annotation 202943_s_at M38083 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M38083.1 /DEF=Human alpha-N-acetylgalactosaminidase mRNA, complete cds. /FEA=mRNA /PROD=alpha-N-acetylgalactosaminidase /DB_XREF=gi:189054 /UG=Hs.75372 N-acetylgalactosaminidase, alpha- /FL=gb:BC000095.1 gb:M62783.1 gb:M38083.1 gb:NM_000262.1" M38083 "N-acetylgalactosaminidase, alpha-" NAGA 4668 NM_000262 /// XM_005261615 /// XM_005261616 /// XM_005261617 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // not recorded /// 0016052 // carbohydrate catabolic process // inferred from direct assay /// 0016139 // glycoside catabolic process // not recorded /// 0019377 // glycolipid catabolic process // inferred from mutant phenotype /// 0046477 // glycosylceramide catabolic process // not recorded 0005737 // cytoplasm // not recorded /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004557 // alpha-galactosidase activity // not recorded /// 0008456 // alpha-N-acetylgalactosaminidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction" 202944_at NM_000262 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000262.1 /DEF=Homo sapiens N-acetylgalactosaminidase, alpha- (NAGA), mRNA. /FEA=mRNA /GEN=NAGA /PROD=alpha-N-acetylgalactosaminidase precursor /DB_XREF=gi:4557780 /UG=Hs.75372 N-acetylgalactosaminidase, alpha- /FL=gb:BC000095.1 gb:M62783.1 gb:M38083.1 gb:NM_000262.1" NM_000262 "N-acetylgalactosaminidase, alpha-" NAGA 4668 NM_000262 /// XM_005261615 /// XM_005261616 /// XM_005261617 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009311 // oligosaccharide metabolic process // not recorded /// 0016052 // carbohydrate catabolic process // inferred from direct assay /// 0016139 // glycoside catabolic process // not recorded /// 0019377 // glycolipid catabolic process // inferred from mutant phenotype /// 0046477 // glycosylceramide catabolic process // not recorded 0005737 // cytoplasm // not recorded /// 0005764 // lysosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004557 // alpha-galactosidase activity // not recorded /// 0008456 // alpha-N-acetylgalactosaminidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction" 202945_at NM_004957 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004957.1 /DEF=Homo sapiens folylpolyglutamate synthase (FPGS), mRNA. /FEA=mRNA /GEN=FPGS /PROD=folylpolyglutamate synthase /DB_XREF=gi:4826727 /UG=Hs.754 folylpolyglutamate synthase /FL=gb:M98045.1 gb:NM_004957.1" NM_004957 folylpolyglutamate synthase FPGS 2356 NM_001018078 /// NM_001288803 /// NM_004957 /// NR_110170 /// XM_005251864 /// XR_242581 /// XR_242582 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006544 // glycine metabolic process // inferred from sequence or structural similarity /// 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from sequence or structural similarity /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // traceable author statement /// 0046901 // tetrahydrofolylpolyglutamate biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004326 // tetrahydrofolylpolyglutamate synthase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 202946_s_at NM_014962 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014962.1 /DEF=Homo sapiens KIAA0952 protein (KIAA0952), mRNA. /FEA=mRNA /GEN=KIAA0952 /PROD=KIAA0952 protein /DB_XREF=gi:7662401 /UG=Hs.7935 KIAA0952 protein /FL=gb:AB023169.1 gb:NM_014962.1" NM_014962 BTB (POZ) domain containing 3 BTBD3 22903 NM_001282550 /// NM_001282551 /// NM_001282552 /// NM_001282554 /// NM_014962 /// NM_181443 /// XM_006723550 /// XM_006723551 0007399 // nervous system development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity 0005515 // protein binding // inferred from electronic annotation 202947_s_at NM_002101 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002101.2 /DEF=Homo sapiens glycophorin C (Gerbich blood group) (GYPC), transcript variant 1, mRNA. /FEA=mRNA /GEN=GYPC /PROD=glycophorin C, isoform 1 /DB_XREF=gi:8051606 /UG=Hs.81994 glycophorin C (Gerbich blood group) /FL=gb:M36284.1 gb:M11802.1 gb:NM_002101.2" NM_002101 glycophorin C (Gerbich blood group) GYPC 2995 NM_001256584 /// NM_002101 /// NM_016815 /// XM_005263653 /// XM_006712460 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 202948_at NM_000877 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000877.1 /DEF=Homo sapiens interleukin 1 receptor, type I (IL1R1), mRNA. /FEA=mRNA /GEN=IL1R1 /PROD=interleukin 1 receptor, type I /DB_XREF=gi:4504658 /UG=Hs.82112 interleukin 1 receptor, type I /FL=gb:M27492.1 gb:NM_000877.1" NM_000877 "interleukin 1 receptor, type I" IL1R1 3554 NM_000877 /// NM_001288706 /// XM_005263929 /// XM_005263930 /// XM_005263931 /// XM_005263932 /// XM_005263933 /// XM_005263934 /// XR_244889 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0070498 // interleukin-1-mediated signaling pathway // inferred from direct assay /// 0070555 // response to interleukin-1 // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation "0002020 // protease binding // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from direct assay /// 0004909 // interleukin-1, Type I, activating receptor activity // inferred from electronic annotation /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction" 202949_s_at NM_001450 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001450.1 /DEF=Homo sapiens four and a half LIM domains 2 (FHL2), mRNA. /FEA=mRNA /GEN=FHL2 /PROD=four and a half LIM domains 2 /DB_XREF=gi:4503722 /UG=Hs.8302 four and a half LIM domains 2 /FL=gb:U29332.1 gb:NM_001450.1" NM_001450 four and a half LIM domains 2 FHL2 2274 NM_001039492 /// NM_001450 /// NM_201555 /// NM_201556 /// NM_201557 /// XM_005263901 /// XM_005263902 /// XM_005263903 /// XM_005263904 /// XM_005263906 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0009725 // response to hormone // inferred from mutant phenotype /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0055014 // atrial cardiac muscle cell development // inferred from electronic annotation /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060347 // heart trabecula formation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 202950_at NM_001889 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001889.1 /DEF=Homo sapiens crystallin, zeta (quinone reductase) (CRYZ), mRNA. /FEA=mRNA /GEN=CRYZ /PROD=crystallin, zeta (quinone reductase) /DB_XREF=gi:4503066 /UG=Hs.83114 crystallin, zeta (quinone reductase) /FL=gb:L13278.1 gb:S58039.1 gb:NM_001889.1" NM_001889 "crystallin, zeta (quinone reductase)" CRYZ 1429 NM_001130042 /// NM_001130043 /// NM_001134759 /// NM_001889 /// XM_005270491 0007601 // visual perception // traceable author statement /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0003960 // NADPH:quinone reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0070402 // NADPH binding // inferred from direct assay /// 0070404 // NADH binding // inferred from direct assay" 202951_at BE048506 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE048506 /FEA=EST /DB_XREF=gi:8365559 /DB_XREF=est:hr49h06.x1 /CLONE=IMAGE:3131867 /UG=Hs.8724 serine threonine protein kinase /FL=gb:NM_007271.1 BE048506 serine/threonine kinase 38 STK38 11329 NM_007271 /// XM_005248839 /// XM_006714988 /// XM_006714989 /// XM_006714990 0006464 // cellular protein modification process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070688 // MLL5-L complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation" 202952_s_at NM_003474 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003474.2 /DEF=Homo sapiens a disintegrin and metalloproteinase domain 12 (meltrin alpha) (ADAM12), transcript variant 1, mRNA. /FEA=mRNA /GEN=ADAM12 /PROD=a disintegrin and metalloprotease domain 12 ,isoform 1 preproprotein /DB_XREF=gi:13259517 /UG=Hs.8850 a disintegrin and metalloproteinase domain 12 (meltrin alpha) /FL=gb:AF023476.2 gb:NM_003474.2" NM_003474 ADAM metallopeptidase domain 12 ADAM12 8038 NM_001288973 /// NM_001288974 /// NM_001288975 /// NM_003474 /// NM_021641 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007520 // myoblast fusion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202953_at NM_000491 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000491.2 /DEF=Homo sapiens complement component 1, q subcomponent, beta polypeptide (C1QB), mRNA. /FEA=mRNA /GEN=C1QB /PROD=complement component 1, q subcomponent, betapolypeptide precursor /DB_XREF=gi:11038661 /UG=Hs.8986 complement component 1, q subcomponent, beta polypeptide /FL=gb:NM_000491.2" NM_000491 "complement component 1, q subcomponent, B chain" C1QB 713 NM_000491 /// XM_005245982 "0002376 // immune system process // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048839 // inner ear development // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005602 // complement component C1 complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation 202954_at NM_007019 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007019.1 /DEF=Homo sapiens ubiquitin carrier protein E2-C (UBCH10), mRNA. /FEA=mRNA /GEN=UBCH10 /PROD=ubiquitin carrier protein E2-C /DB_XREF=gi:5902145 /UG=Hs.93002 ubiquitin carrier protein E2-C /FL=gb:U73379.1 gb:NM_007019.1" NM_007019 ubiquitin-conjugating enzyme E2C UBE2C 11065 NM_001281741 /// NM_001281742 /// NM_007019 /// NM_181799 /// NM_181800 /// NM_181801 /// NM_181802 /// NM_181803 /// NR_104036 /// NR_104037 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0010458 // exit from mitosis // inferred from mutant phenotype /// 0010994 // free ubiquitin chain polymerization // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051488 // activation of anaphase-promoting complex activity // traceable author statement /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 202955_s_at AF084520 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF084520.1 /DEF=Homo sapiens brefeldin A-inhibited guanine nucleotide-exchange protein 1 mRNA, complete cds. /FEA=mRNA /PROD=brefeldin A-inhibited guaninenucleotide-exchange protein 1 /DB_XREF=gi:5052120 /UG=Hs.94631 brefeldin A-inhibited guanine nucleotide-exchange protein 1 /FL=gb:AF084520.1 gb:AF111162.1 gb:NM_006421.2" AF084520 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) ARFGEF1 10565 NM_006421 /// XM_005251134 /// XM_005251135 /// XM_005251136 /// XM_006716418 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0030837 // negative regulation of actin filament polymerization // inferred from mutant phenotype /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0034259 // negative regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0090284 // positive regulation of protein glycosylation in Golgi // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0017022 // myosin binding // inferred from physical interaction /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay 202956_at NM_006421 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006421.2 /DEF=Homo sapiens brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1), mRNA. /FEA=mRNA /GEN=BIG1 /PROD=brefeldin A-inhibited guaninenucleotide-exchange protein 1 /DB_XREF=gi:6715588 /UG=Hs.94631 brefeldin A-inhibited guanine nucleotide-exchange protein 1 /FL=gb:AF084520.1 gb:AF111162.1 gb:NM_006421.2" NM_006421 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) ARFGEF1 10565 NM_006421 /// XM_005251134 /// XM_005251135 /// XM_005251136 /// XM_006716418 0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // traceable author statement /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0010256 // endomembrane system organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // not recorded /// 0030837 // negative regulation of actin filament polymerization // inferred from mutant phenotype /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0034259 // negative regulation of Rho GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0090284 // positive regulation of protein glycosylation in Golgi // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype /// 2000114 // regulation of establishment of cell polarity // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // not recorded /// 0005802 // trans-Golgi network // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008060 // ARF GTPase activator activity // inferred from direct assay /// 0017022 // myosin binding // inferred from physical interaction /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay 202957_at NM_005335 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005335.1 /DEF=Homo sapiens hematopoietic cell-specific Lyn substrate 1 (HCLS1), mRNA. /FEA=mRNA /GEN=HCLS1 /PROD=hematopoietic cell-specific Lyn substrate 1 /DB_XREF=gi:4885404 /UG=Hs.14601 hematopoietic cell-specific Lyn substrate 1 /FL=gb:NM_005335.1" NM_005335 hematopoietic cell-specific Lyn substrate 1 HCLS1 3059 NM_001292041 /// NM_005335 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030833 // regulation of actin filament polymerization // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0042531 // positive regulation of tyrosine phosphorylation of STAT protein // inferred from sequence or structural similarity /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0071345 // cellular response to cytokine stimulus // inferred from mutant phenotype /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from mutant phenotype /// 2000251 // positive regulation of actin cytoskeleton reorganization // inferred by curator" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 202958_at NM_002833 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002833.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 9 (PTPN9), mRNA. /FEA=mRNA /GEN=PTPN9 /PROD=protein tyrosine phosphatase, non-receptor type9 /DB_XREF=gi:4506300 /UG=Hs.147663 protein tyrosine phosphatase, non-receptor type 9 /FL=gb:M83738.1 gb:NM_002833.1" NM_002833 "protein tyrosine phosphatase, non-receptor type 9" PTPN9 5780 NM_002833 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 202959_at AI433712 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI433712 /FEA=EST /DB_XREF=gi:4291098 /DB_XREF=est:ti88f08.x1 /CLONE=IMAGE:2139111 /UG=Hs.155212 methylmalonyl Coenzyme A mutase /FL=gb:M65131.1 gb:NM_000255.1 AI433712 methylmalonyl CoA mutase MUT 4594 NM_000255 /// XM_005249143 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004494 // methylmalonyl-CoA mutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation /// 0031419 // cobalamin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 202960_s_at NM_000255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000255.1 /DEF=Homo sapiens methylmalonyl Coenzyme A mutase (MUT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MUT /PROD=methylmalonyl Coenzyme A mutase precursor /DB_XREF=gi:4557766 /UG=Hs.155212 methylmalonyl Coenzyme A mutase /FL=gb:M65131.1 gb:NM_000255.1" NM_000255 methylmalonyl CoA mutase MUT 4594 NM_000255 /// XM_005249143 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050667 // homocysteine metabolic process // inferred from direct assay 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004494 // methylmalonyl-CoA mutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016866 // intramolecular transferase activity // inferred from electronic annotation /// 0031419 // cobalamin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay 202961_s_at NM_004889 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004889.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 (ATP5J2), mRNA. /FEA=mRNA /GEN=ATP5J2 /PROD=ATP synthase, H+ transporting, mitochondrial F0complex, subunit f, isoform 2 /DB_XREF=gi:4757811 /UG=Hs.155751 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 /FL=gb:BC003678.1 gb:AF047436.1 gb:NM_004889.1" NM_004889 "ARMC2 antisense RNA 1 /// ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2" ARMC2-AS1 /// ATP5J2 9551 /// 101929716 NM_001003713 /// NM_001003714 /// NM_001039178 /// NM_001190353 /// NM_001190354 /// NM_004889 /// NR_104137 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement "0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o) // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator 202962_at NM_015254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015254.1 /DEF=Homo sapiens kinesin family member 13B (KIF13B), mRNA. /FEA=mRNA /GEN=KIF13B /PROD=kinesin family member 13B /DB_XREF=gi:13194196 /UG=Hs.15711 kinesin family member 13B /FL=gb:AL583912.1 gb:NM_015254.1 gb:AF279865.1" NM_015254 kinesin family member 13B KIF13B 23303 NM_015254 /// XM_005273458 /// XM_005273459 /// XM_006716316 /// XM_006716317 0006605 // protein targeting // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0050770 // regulation of axonogenesis // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0071889 // 14-3-3 protein binding // inferred from direct assay 202963_at AW027312 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW027312 /FEA=EST /DB_XREF=gi:5886068 /DB_XREF=est:wt73b04.x1 /CLONE=IMAGE:2513071 /UG=Hs.166891 regulatory factor X, 5 (influences HLA class II expression) /FL=gb:NM_000449.1" AW027312 "regulatory factor X, 5 (influences HLA class II expression)" RFX5 5993 NM_000449 /// NM_001025603 /// XM_005245405 /// XM_005245406 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202964_s_at NM_000449 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000449.1 /DEF=Homo sapiens regulatory factor X, 5 (influences HLA class II expression) (RFX5), mRNA. /FEA=mRNA /GEN=RFX5 /PROD=regulatory factor X, 5 /DB_XREF=gi:4557842 /UG=Hs.166891 regulatory factor X, 5 (influences HLA class II expression) /FL=gb:NM_000449.1" NM_000449 "regulatory factor X, 5 (influences HLA class II expression)" RFX5 5993 NM_000449 /// NM_001025603 /// XM_005245405 /// XM_005245406 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202965_s_at NM_014289 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014289.2 /DEF=Homo sapiens calpain 6 (CAPN6), mRNA. /FEA=mRNA /GEN=CAPN6 /PROD=calpain 6 /DB_XREF=gi:13186315 /UG=Hs.169172 calpain 6 /FL=gb:BC000730.1 gb:NM_014289.2 gb:AF029232.1" NM_014289 calpain 6 CAPN6 827 NM_014289 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0006508 // proteolysis // not recorded /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity 202966_at NM_014289 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014289.2 /DEF=Homo sapiens calpain 6 (CAPN6), mRNA. /FEA=mRNA /GEN=CAPN6 /PROD=calpain 6 /DB_XREF=gi:13186315 /UG=Hs.169172 calpain 6 /FL=gb:BC000730.1 gb:NM_014289.2 gb:AF029232.1" NM_014289 calpain 6 CAPN6 827 NM_014289 0001578 // microtubule bundle formation // inferred from sequence or structural similarity /// 0006508 // proteolysis // not recorded /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from sequence or structural similarity 202967_at NM_001512 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001512.1 /DEF=Homo sapiens glutathione S-transferase A4 (GSTA4), mRNA. /FEA=mRNA /GEN=GSTA4 /PROD=glutathione S-transferase A4 /DB_XREF=gi:4504172 /UG=Hs.169907 glutathione S-transferase A4 /FL=gb:AF020918.1 gb:AF025887.1 gb:NM_001512.1 gb:AF125271.1 gb:AF125272.1 gb:AF125273.1" NM_001512 glutathione S-transferase alpha 4 GSTA4 2941 NM_001512 /// XM_005249035 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 202968_s_at Y09216 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:Y09216.1 /DEF=H.sapiens mRNA for protein kinase, Dyrk2. /FEA=mRNA /GEN=Dyrk2 /DB_XREF=gi:1666065 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1" Y09216 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay" 202969_at AI216690 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI216690 /FEA=EST /DB_XREF=gi:3785731 /DB_XREF=est:qg66h07.x1 /CLONE=IMAGE:1840189 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1 AI216690 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay" 202970_at AI192838 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI192838 /FEA=EST /DB_XREF=gi:3744047 /DB_XREF=est:qe63c04.x1 /CLONE=IMAGE:1743654 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1 AI192838 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay" 202971_s_at NM_006482 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006482.1 /DEF=Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2), transcript variant 2, mRNA. /FEA=mRNA /GEN=DYRK2 /PROD=dual-specificity tyrosine-(Y)-phosphorylationregulated kinase 2 isoform 2 /DB_XREF=gi:5922003 /UG=Hs.173135 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 /FL=gb:NM_006482.1" NM_006482 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 DYRK2 8445 NM_003583 /// NM_006482 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from expression pattern /// 0007224 // smoothened signaling pathway // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from direct assay /// 0051534 // negative regulation of NFAT protein import into nucleus // inferred from mutant phenotype 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay" 202972_s_at AW450403 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW450403 /FEA=EST /DB_XREF=gi:6991179 /DB_XREF=est:UI-H-BI3-akn-g-07-0-UI.s1 /CLONE=IMAGE:2735029 /UG=Hs.177664 KIAA0914 gene product /FL=gb:AB020721.1 gb:NM_014883.1 AW450403 "family with sequence similarity 13, member A" FAM13A 10144 NM_001015045 /// NM_001265578 /// NM_001265579 /// NM_001265580 /// NM_014883 /// XM_005262681 /// XM_005262682 /// XM_005262683 /// XM_005262684 /// XM_005262685 /// XM_006714057 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 202973_x_at NM_014883 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014883.1 /DEF=Homo sapiens KIAA0914 gene product (KIAA0914), mRNA. /FEA=mRNA /GEN=KIAA0914 /PROD=KIAA0914 gene product /DB_XREF=gi:7662375 /UG=Hs.177664 KIAA0914 gene product /FL=gb:AB020721.1 gb:NM_014883.1" NM_014883 "family with sequence similarity 13, member A" FAM13A 10144 NM_001015045 /// NM_001265578 /// NM_001265579 /// NM_001265580 /// NM_014883 /// XM_005262681 /// XM_005262682 /// XM_005262683 /// XM_005262684 /// XM_005262685 /// XM_006714057 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation 202974_at NM_002436 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002436.2 /DEF=Homo sapiens membrane protein, palmitoylated 1 (55kD) (MPP1), mRNA. /FEA=mRNA /GEN=MPP1 /PROD=palmitoylated membrane protein 1 /DB_XREF=gi:6006024 /UG=Hs.1861 membrane protein, palmitoylated 1 (55kD) /FL=gb:BC002392.1 gb:M64925.1 gb:NM_002436.2" NM_002436 "membrane protein, palmitoylated 1, 55kDa" MPP1 4354 NM_001166460 /// NM_001166461 /// NM_001166462 /// NM_002436 0007165 // signal transduction // traceable author statement /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0090022 // regulation of neutrophil chemotaxis // inferred from sequence or structural similarity 0005622 // intracellular // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 202975_s_at N21138 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N21138 /FEA=EST /DB_XREF=gi:1126308 /DB_XREF=est:yx52h03.s1 /CLONE=IMAGE:265397 /UG=Hs.188006 KIAA0878 protein /FL=gb:AB020685.1 gb:NM_014899.1 N21138 Rho-related BTB domain containing 3 RHOBTB3 22836 NM_014899 "0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype" 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 202976_s_at NM_014899 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014899.1 /DEF=Homo sapiens KIAA0878 protein (KIAA0878), mRNA. /FEA=mRNA /GEN=KIAA0878 /PROD=KIAA0878 protein /DB_XREF=gi:7662355 /UG=Hs.188006 KIAA0878 protein /FL=gb:AB020685.1 gb:NM_014899.1" NM_014899 Rho-related BTB domain containing 3 RHOBTB3 22836 NM_014899 "0006200 // ATP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype" 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from physical interaction 202977_s_at AI206560 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI206560 /FEA=EST /DB_XREF=gi:3765232 /DB_XREF=est:qf61g11.x1 /CLONE=IMAGE:1754564 /UG=Hs.29417 HCF-binding transcription factor Zhangfei /FL=gb:NM_021212.1 gb:AF039942.1 AI206560 CREB/ATF bZIP transcription factor CREBZF 58487 NM_001039618 /// NM_021212 /// NR_028024 /// NR_028025 /// NR_028026 /// NR_028027 /// XM_005274135 /// XM_005274136 /// XM_005274138 /// XM_006718642 /// XM_006718643 /// XM_006718644 /// XM_006718645 "0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay" 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202978_s_at AW204564 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW204564 /FEA=EST /DB_XREF=gi:6504036 /DB_XREF=est:UI-H-BI1-aec-e-07-0-UI.s1 /CLONE=IMAGE:2718828 /UG=Hs.29417 HCF-binding transcription factor Zhangfei /FL=gb:NM_021212.1 gb:AF039942.1 AW204564 CREB/ATF bZIP transcription factor CREBZF 58487 NM_001039618 /// NM_021212 /// NR_028024 /// NR_028025 /// NR_028026 /// NR_028027 /// XM_005274135 /// XM_005274136 /// XM_005274138 /// XM_006718642 /// XM_006718643 /// XM_006718644 /// XM_006718645 "0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay" 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202979_s_at NM_021212 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021212.1 /DEF=Homo sapiens HCF-binding transcription factor Zhangfei (ZF), mRNA. /FEA=mRNA /GEN=ZF /PROD=HCF-binding transcription factor Zhangfei /DB_XREF=gi:10864024 /UG=Hs.29417 HCF-binding transcription factor Zhangfei /FL=gb:NM_021212.1 gb:AF039942.1" NM_021212 CREB/ATF bZIP transcription factor CREBZF 58487 NM_001039618 /// NM_021212 /// NR_028024 /// NR_028025 /// NR_028026 /// NR_028027 /// XM_005274135 /// XM_005274136 /// XM_005274138 /// XM_006718642 /// XM_006718643 /// XM_006718644 /// XM_006718645 "0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0045814 // negative regulation of gene expression, epigenetic // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay" 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 202980_s_at AI953523 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI953523 /FEA=EST /DB_XREF=gi:5745833 /DB_XREF=est:wq29g12.x1 /CLONE=IMAGE:2472742 /UG=Hs.295923 seven in absentia (Drosophila) homolog 1 /FL=gb:U76247.1 gb:U63295.1 gb:NM_003031.1 AI953523 siah E3 ubiquitin protein ligase 1 SIAH1 6477 NM_001006610 /// NM_003031 /// XM_006721246 0006200 // ATP catabolic process // /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006515 // misfolded or incompletely synthesized protein catabolic process // /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007031 // peroxisome organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016485 // protein processing // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031998 // regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0004176 // ATP-dependent peptidase activity // /// 0004176 // ATP-dependent peptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202981_x_at NM_003031 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003031.1 /DEF=Homo sapiens seven in absentia (Drosophila) homolog 1 (SIAH1), mRNA. /FEA=mRNA /GEN=SIAH1 /PROD=seven in absentia (Drosophila) homolog 1 /DB_XREF=gi:4506946 /UG=Hs.295923 seven in absentia (Drosophila) homolog 1 /FL=gb:U76247.1 gb:U63295.1 gb:NM_003031.1" NM_003031 siah E3 ubiquitin protein ligase 1 SIAH1 6477 NM_001006610 /// NM_003031 /// XM_006721246 0006200 // ATP catabolic process // /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006515 // misfolded or incompletely synthesized protein catabolic process // /// 0006515 // misfolded or incompletely synthesized protein catabolic process // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007031 // peroxisome organization // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016485 // protein processing // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from direct assay /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031998 // regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from physical interaction /// 0004176 // ATP-dependent peptidase activity // /// 0004176 // ATP-dependent peptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 202982_s_at NM_006821 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006821.1 /DEF=Homo sapiens peroxisomal long-chain acyl-coA thioesterase (ZAP128), mRNA. /FEA=mRNA /GEN=ZAP128 /PROD=peroxisomal long-chain acyl-coA thioesterase /DB_XREF=gi:13375613 /UG=Hs.299629 peroxisomal long-chain acyl-coA thioesterase /FL=gb:BC004436.1 gb:NM_006821.1 gb:AY005822.1" NM_006821 acyl-CoA thioesterase 1 /// acyl-CoA thioesterase 2 ACOT1 /// ACOT2 10965 /// 641371 NM_001037161 /// NM_006821 /// NR_046028 /// XM_006720007 0000038 // very long-chain fatty acid metabolic process // inferred from direct assay /// 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006637 // acyl-CoA metabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016790 // thiolester hydrolase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // inferred from direct assay 202983_at AI760760 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI760760 /FEA=EST /DB_XREF=gi:5176427 /DB_XREF=est:wi67b09.x1 /CLONE=IMAGE:2398361 /UG=Hs.3068 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 /FL=gb:NM_003071.1" AI760760 helicase-like transcription factor HLTF 6596 NM_003071 /// NM_139048 /// XM_005247724 "0006200 // ATP catabolic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 202984_s_at AA457021 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA457021 /FEA=EST /DB_XREF=gi:2179741 /DB_XREF=est:aa38a08.s1 /CLONE=IMAGE:815510 /UG=Hs.5443 BCL2-associated athanogene 5 /FL=gb:AF095195.2 gb:NM_004873.1 AA457021 BCL2-associated athanogene 5 BAG5 9529 NM_001015048 /// NM_001015049 /// NM_004873 0006457 // protein folding // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0061084 // negative regulation of protein refolding // inferred from sequence or structural similarity /// 0070997 // neuron death // inferred from sequence or structural similarity /// 0090083 // regulation of inclusion body assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 202985_s_at NM_004873 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004873.1 /DEF=Homo sapiens BCL2-associated athanogene 5 (BAG5), mRNA. /FEA=mRNA /GEN=BAG5 /PROD=BCL2-associated athanogene 5 /DB_XREF=gi:6631076 /UG=Hs.5443 BCL2-associated athanogene 5 /FL=gb:AF095195.2 gb:NM_004873.1" NM_004873 BCL2-associated athanogene 5 BAG5 9529 NM_001015048 /// NM_001015049 /// NM_004873 0006457 // protein folding // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from sequence or structural similarity /// 0061084 // negative regulation of protein refolding // inferred from sequence or structural similarity /// 0070997 // neuron death // inferred from sequence or structural similarity /// 0090083 // regulation of inclusion body assembly // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016234 // inclusion body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 202986_at NM_014862 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014862.1 /DEF=Homo sapiens KIAA0307 gene product (KIAA0307), mRNA. /FEA=mRNA /GEN=KIAA0307 /PROD=KIAA0307 gene product /DB_XREF=gi:7662049 /UG=Hs.6111 KIAA0307 gene product /FL=gb:AB002305.1 gb:NM_014862.1" NM_014862 aryl-hydrocarbon receptor nuclear translocator 2 ARNT2 9915 NM_014862 "0001666 // response to hypoxia // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017162 // aryl hydrocarbon receptor binding // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation 202987_at AW296296 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW296296 /FEA=EST /DB_XREF=gi:6702922 /DB_XREF=est:UI-H-BI2-aid-c-12-0-UI.s1 /CLONE=IMAGE:2728727 /UG=Hs.7446 DKFZP586G0522 protein /FL=gb:AF274303.1 gb:AF272151.1 gb:BC002823.1 gb:AL050289.1 gb:NM_015524.1 AW296296 TRAF3 interacting protein 2 TRAF3IP2 10758 NM_001164281 /// NM_001164282 /// NM_001164283 /// NM_147200 /// NM_147686 /// NR_028338 /// XM_006715319 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0006959 // humoral immune response // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0048305 // immunoglobulin secretion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 202988_s_at NM_002922 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002922.1 /DEF=Homo sapiens regulator of G-protein signalling 1 (RGS1), mRNA. /FEA=mRNA /GEN=RGS1 /PROD=regulator of G-protein signalling 1 /DB_XREF=gi:4506514 /UG=Hs.75256 regulator of G-protein signalling 1 /FL=gb:NM_002922.1" NM_002922 regulator of G-protein signaling 1 RGS1 5996 NM_002922 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 202989_at NM_002922 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002922.1 /DEF=Homo sapiens regulator of G-protein signalling 1 (RGS1), mRNA. /FEA=mRNA /GEN=RGS1 /PROD=regulator of G-protein signalling 1 /DB_XREF=gi:4506514 /UG=Hs.75256 regulator of G-protein signalling 1 /FL=gb:NM_002922.1" NM_002922 regulator of G-protein signaling 1 RGS1 5996 NM_002922 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 202990_at NM_002863 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002863.1 /DEF=Homo sapiens phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) (PYGL), mRNA. /FEA=mRNA /GEN=PYGL /PROD=phosphorylase, glycogen; liver (Hers disease,glycogen storage disease type VI) /DB_XREF=gi:4506352 /UG=Hs.771 phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) /FL=gb:M14636.1 gb:AF066858.1 gb:AF046785.1 gb:NM_002863.1" NM_002863 "phosphorylase, glycogen, liver" PYGL 5836 NM_001163940 /// NM_002863 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from mutant phenotype /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0002060 // purine nucleobase binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005536 // glucose binding // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0008184 // glycogen phosphorylase activity // not recorded /// 0008184 // glycogen phosphorylase activity // inferred from direct assay /// 0008184 // glycogen phosphorylase activity // inferred from mutant phenotype /// 0016208 // AMP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0019842 // vitamin binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0032052 // bile acid binding // inferred from direct assay /// 0042803 // protein homodimerization activity // non-traceable author statement" 202991_at NM_006804 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006804.1 /DEF=Homo sapiens steroidogenic acute regulatory protein related (MLN64), mRNA. /FEA=mRNA /GEN=MLN64 /PROD=steroidogenic acute regulatory protein related /DB_XREF=gi:5803089 /UG=Hs.77628 steroidogenic acute regulatory protein related /FL=gb:D38255.1 gb:NM_006804.1" NM_006804 StAR-related lipid transfer (START) domain containing 3 STARD3 10948 NM_001165937 /// NM_001165938 /// NM_006804 /// XM_006721645 /// XM_006721646 /// XR_243628 /// XR_429868 0006629 // lipid metabolic process // traceable author statement /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006701 // progesterone biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // traceable author statement /// 0030301 // cholesterol transport // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0008289 // lipid binding // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation 202992_at NM_000587 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000587.1 /DEF=Homo sapiens complement component 7 (C7), mRNA. /FEA=mRNA /GEN=C7 /PROD=complement component 7 precursor /DB_XREF=gi:4557386 /UG=Hs.78065 complement component 7 /FL=gb:J03507.1 gb:NM_000587.1" NM_000587 complement component 7 C7 730 NM_000587 "0002376 // immune system process // inferred from electronic annotation /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0019835 // cytolysis // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement" 0005576 // extracellular region // traceable author statement /// 0005579 // membrane attack complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 202993_at NM_006844 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006844.1 /DEF=Homo sapiens ilvB (bacterial acetolactate synthase)-like (ILVBL), mRNA. /FEA=mRNA /GEN=ILVBL /PROD=ilvB (bacterial acetolactate synthase)-like /DB_XREF=gi:5803041 /UG=Hs.78880 ilvB (bacterial acetolactate synthase)-like /FL=gb:U61263.1 gb:NM_006844.1" NM_006844 ilvB (bacterial acetolactate synthase)-like ILVBL 10994 NM_006844 /// NM_176826 /// XM_005259717 0008152 // metabolic process // inferred from electronic annotation 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 202994_s_at Z95331 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:Z95331 /DEF=Human DNA sequence from clone CTA-941F9 on chromosome 22q13 Contains the 3 end of the FBLN1 gene for Fibulin 1 isoforms B, C and D, the first exon of the gene for a novel protein (the ortholog of mouse brain protein E46), ESTs, STSs, GSSs and two... /FEA=mRNA_1 /DB_XREF=gi:6572282 /UG=Hs.79732 fibulin 1 /FL=gb:U01244.1 gb:NM_006486.1" Z95331 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 202995_s_at NM_006486 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006486.1 /DEF=Homo sapiens fibulin 1 (FBLN1), transcript variant D, mRNA. /FEA=mRNA /GEN=FBLN1 /PROD=fibulin 1 isoform D /DB_XREF=gi:5922008 /UG=Hs.79732 fibulin 1 /FL=gb:U01244.1 gb:NM_006486.1" NM_006486 fibulin 1 FBLN1 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 0007566 // embryo implantation // inferred from electronic annotation /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016504 // peptidase activator activity // inferred from electronic annotation 202996_at NM_021173 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021173.1 /DEF=Homo sapiens polymerase (DNA-directed), delta 4 (POLD4), mRNA. /FEA=mRNA /GEN=POLD4 /PROD=polymerase (DNA-directed), delta 4 /DB_XREF=gi:10863968 /UG=Hs.82520 polymerase (DNA-directed), delta 4 /FL=gb:NM_021173.1 gb:BC001334.1 gb:AF179890.1" NM_021173 "polymerase (DNA-directed), delta 4, accessory subunit" POLD4 57804 NM_001256870 /// NM_021173 /// NR_046411 /// NR_046412 /// NR_046413 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 202997_s_at BE251211 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE251211 /FEA=EST /DB_XREF=gi:9121333 /DB_XREF=est:601116312F1 /CLONE=IMAGE:3356954 /UG=Hs.83354 lysyl oxidase-like 2 /FL=gb:BC000594.1 gb:U89942.1 gb:NM_002318.1 gb:AF117949.1 BE251211 lysyl oxidase-like 2 LOXL2 4017 NM_002318 "0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007568 // aging // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016570 // histone modification // inferred from direct assay /// 0018277 // protein deamination // inferred from direct assay /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046688 // response to copper ion // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004720 // protein-lysine 6-oxidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070492 // oligosaccharide binding // inferred from direct assay" 202998_s_at NM_002318 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002318.1 /DEF=Homo sapiens lysyl oxidase-like 2 (LOXL2), mRNA. /FEA=mRNA /GEN=LOXL2 /PROD=lysyl oxidase-like 2 /DB_XREF=gi:4505010 /UG=Hs.83354 lysyl oxidase-like 2 /FL=gb:BC000594.1 gb:U89942.1 gb:NM_002318.1 gb:AF117949.1" NM_002318 lysyl oxidase-like 2 LOXL2 4017 NM_002318 "0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007568 // aging // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016570 // histone modification // inferred from direct assay /// 0018277 // protein deamination // inferred from direct assay /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046688 // response to copper ion // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004720 // protein-lysine 6-oxidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070492 // oligosaccharide binding // inferred from direct assay" 202999_s_at AF117949 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF117949.1 /DEF=Homo sapiens lysyl oxidase-like protein 2 (LOXL2) mRNA, complete cds. /FEA=mRNA /GEN=LOXL2 /PROD=lysyl oxidase-like protein 2 /DB_XREF=gi:4959424 /UG=Hs.83354 lysyl oxidase-like 2 /FL=gb:BC000594.1 gb:U89942.1 gb:NM_002318.1 gb:AF117949.1" AF117949 lysyl oxidase-like 2 LOXL2 4017 NM_002318 "0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006464 // cellular protein modification process // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007568 // aging // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016570 // histone modification // inferred from direct assay /// 0018277 // protein deamination // inferred from direct assay /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0032332 // positive regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046688 // response to copper ion // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay" 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0003682 // chromatin binding // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004720 // protein-lysine 6-oxidase activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070492 // oligosaccharide binding // inferred from direct assay" 203000_at BF967657 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF967657 /FEA=EST /DB_XREF=gi:12334872 /DB_XREF=est:602287358T1 /CLONE=IMAGE:4374495 /UG=Hs.90005 superiorcervical ganglia, neural specific 10 /FL=gb:D50375.1 gb:NM_007029.1" BF967657 stathmin 2 STMN2 11075 NM_001199214 /// NM_007029 /// XM_005251142 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030182 // neuron differentiation // non-traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031117 // positive regulation of microtubule depolymerization // inferred from direct assay /// 1990090 // cellular response to nerve growth factor stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 203001_s_at NM_007029 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007029.1 /DEF=Homo sapiens superiorcervical ganglia, neural specific 10 (SCGN10), mRNA. /FEA=mRNA /GEN=SCGN10 /PROD=superiorcervical ganglia, neural specific 10 /DB_XREF=gi:5902079 /UG=Hs.90005 superiorcervical ganglia, neural specific 10 /FL=gb:D50375.1 gb:NM_007029.1" NM_007029 stathmin 2 STMN2 11075 NM_001199214 /// NM_007029 /// XM_005251142 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0030182 // neuron differentiation // non-traceable author statement /// 0031110 // regulation of microtubule polymerization or depolymerization // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0031117 // positive regulation of microtubule depolymerization // inferred from direct assay /// 1990090 // cellular response to nerve growth factor stimulus // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction 203002_at NM_016201 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016201.1 /DEF=Homo sapiens Leman coiled-coil protein (LCCP), mRNA. /FEA=mRNA /GEN=LCCP /PROD=Leman coiled-coil protein /DB_XREF=gi:7705577 /UG=Hs.92186 Leman coiled-coil protein /FL=gb:AF175966.1 gb:NM_016201.1" NM_016201 angiomotin like 2 AMOTL2 51421 NM_001278683 /// NM_001278685 /// NM_016201 /// XM_005247520 /// XM_006713654 /// XM_006713655 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 203003_at AL530331 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL530331 /FEA=EST /DB_XREF=gi:12793824 /DB_XREF=est:AL530331 /CLONE=CS0DD007YM06 (3 prime) /UG=Hs.111243 MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) /FL=gb:L16794.1 gb:NM_005920.1" AL530331 myocyte enhancer factor 2D MEF2D 4209 NM_001271629 /// NM_005920 /// XM_005245169 /// XM_005245170 /// XM_006711330 /// XM_006711331 /// XM_006711332 /// XM_006711333 /// XM_006711334 "0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from expression pattern /// 0007517 // muscle organ development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 203004_s_at NM_005920 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005920.1 /DEF=Homo sapiens MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) (MEF2D), mRNA. /FEA=mRNA /GEN=MEF2D /PROD=MADS box transcription enhancer factor 2,polypeptide D (myocyte enhancer factor 2D) /DB_XREF=gi:5174544 /UG=Hs.111243 MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) /FL=gb:L16794.1 gb:NM_005920.1" NM_005920 myocyte enhancer factor 2D MEF2D 4209 NM_001271629 /// NM_005920 /// XM_005245169 /// XM_005245170 /// XM_006711330 /// XM_006711331 /// XM_006711332 /// XM_006711333 /// XM_006711334 "0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007512 // adult heart development // inferred from expression pattern /// 0007517 // muscle organ development // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation 203005_at NM_002342 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002342.1 /DEF=Homo sapiens lymphotoxin beta receptor (TNFR superfamily, member 3 (LTBR), mRNA. /FEA=mRNA /GEN=LTBR /PROD=lymphotoxin B receptor /DB_XREF=gi:4505038 /UG=Hs.1116 lymphotoxin beta receptor (TNFR superfamily, member 3 /FL=gb:L04270.1 gb:NM_002342.1" NM_002342 "lymphotoxin beta receptor (TNFR superfamily, member 3)" LTBR 4055 NM_001270987 /// NM_002342 /// XM_005253688 /// XM_006718983 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 203006_at NM_005539 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005539.1 /DEF=Homo sapiens inositol polyphosphate-5-phosphatase, 40kD (INPP5A), mRNA. /FEA=mRNA /GEN=INPP5A /PROD=inositol polyphosphate-5-phosphatase, 40kD /DB_XREF=gi:5031796 /UG=Hs.124029 inositol polyphosphate-5-phosphatase, 40kD /FL=gb:NM_005539.1" NM_005539 "inositol polyphosphate-5-phosphatase, 40kDa" INPP5A 3632 NM_005539 0007154 // cell communication // non-traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004445 // inositol-polyphosphate 5-phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042731 // PH domain binding // inferred from physical interaction /// 0052658 // inositol-1,4,5-trisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0052659 // inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity // inferred from electronic annotation" 203007_x_at AF077198 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF077198.1 /DEF=Homo sapiens lysophospholipase mRNA, complete cds. /FEA=mRNA /PROD=lysophospholipase /DB_XREF=gi:4679009 /UG=Hs.12540 lysophospholipase I /FL=gb:AF081281.1 gb:AF077198.1 gb:NM_006330.1 gb:AF291053.1" AF077198 lysophospholipase I LYPLA1 10434 NM_001279356 /// NM_001279357 /// NM_001279358 /// NM_001279359 /// NM_001279360 /// NM_006330 /// XM_005251127 /// XM_006716417 /// XR_428339 0002084 // protein depalmitoylation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004622 // lysophospholipase activity // traceable author statement /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from mutant phenotype /// 0008474 // palmitoyl-(protein) hydrolase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 203008_x_at NM_005783 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005783.1 /DEF=Homo sapiens ATP binding protein associated with cell differentiation (APACD), mRNA. /FEA=mRNA /GEN=APACD /PROD=ATP binding protein associated with celldifferentiation /DB_XREF=gi:5031582 /UG=Hs.153884 ATP binding protein associated with cell differentiation /FL=gb:AB006679.1 gb:NM_005783.1" NM_005783 thioredoxin domain containing 9 TXNDC9 10190 NM_005783 0045454 // cell redox homeostasis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203009_at NM_005581 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005581.1 /DEF=Homo sapiens Lutheran blood group (Auberger b antigen included) (LU), mRNA. /FEA=mRNA /GEN=LU /PROD=Lutheran blood group (Auberger b antigenincluded) /DB_XREF=gi:5031890 /UG=Hs.155048 Lutheran blood group (Auberger b antigen included) /FL=gb:NM_005581.1" NM_005581 basal cell adhesion molecule (Lutheran blood group) BCAM 4059 NM_001013257 /// NM_005581 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred by curator /// 0009986 // cell surface // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005055 // laminin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from mutant phenotype 203010_at NM_003152 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003152.1 /DEF=Homo sapiens signal transducer and activator of transcription 5A (STAT5A), mRNA. /FEA=mRNA /GEN=STAT5A /PROD=signal transducer and activator of transcription5A /DB_XREF=gi:4507256 /UG=Hs.167503 signal transducer and activator of transcription 5A /FL=gb:U43185.1 gb:NM_003152.1 gb:L41142.1" NM_003152 signal transducer and activator of transcription 5A STAT5A 6776 NM_001288718 /// NM_001288719 /// NM_001288720 /// NM_003152 /// XM_005257624 "0000255 // allantoin metabolic process // inferred from sequence or structural similarity /// 0001553 // luteinization // inferred from electronic annotation /// 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006101 // citrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006549 // isoleucine metabolic process // inferred from sequence or structural similarity /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006600 // creatine metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019218 // regulation of steroid metabolic process // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032825 // positive regulation of natural killer cell differentiation // inferred from electronic annotation /// 0033026 // negative regulation of mast cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0038161 // prolactin signaling pathway // inferred from sequence or structural similarity /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045588 // positive regulation of gamma-delta T cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from electronic annotation /// 0046449 // creatinine metabolic process // inferred from sequence or structural similarity /// 0046543 // development of secondary female sexual characteristics // inferred from electronic annotation /// 0046544 // development of secondary male sexual characteristics // inferred from electronic annotation /// 0048541 // Peyer's patch development // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0060376 // positive regulation of mast cell differentiation // inferred from electronic annotation /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0060742 // epithelial cell differentiation involved in prostate gland development // inferred from electronic annotation /// 0061180 // mammary gland epithelium development // inferred from electronic annotation /// 0070668 // positive regulation of mast cell proliferation // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203011_at NM_005536 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005536.2 /DEF=Homo sapiens inositol(myo)-1(or 4)-monophosphatase 1 (IMPA1), mRNA. /FEA=mRNA /GEN=IMPA1 /PROD=inositol(myo)-1(or 4)-monophosphatase 1 /DB_XREF=gi:8393607 /UG=Hs.171776 inositol(myo)-1(or 4)-monophosphatase 1 /FL=gb:AF042729.2 gb:NM_005536.2" NM_005536 inositol(myo)-1(or 4)-monophosphatase 1 IMPA1 3612 NM_001144878 /// NM_001144879 /// NM_005536 0006021 // inositol biosynthetic process // inferred from electronic annotation /// 0006661 // phosphatidylinositol biosynthetic process // inferred from mutant phenotype /// 0006796 // phosphate-containing compound metabolic process // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from mutant phenotype /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008934 // inositol monophosphate 1-phosphatase activity // inferred from direct assay /// 0008934 // inositol monophosphate 1-phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052832 // inositol monophosphate 3-phosphatase activity // inferred from electronic annotation /// 0052833 // inositol monophosphate 4-phosphatase activity // inferred from electronic annotation /// 0052834 // inositol monophosphate phosphatase activity // inferred from electronic annotation 203012_x_at NM_000984 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000984.1 /DEF=Homo sapiens ribosomal protein L23a (RPL23A), mRNA. /FEA=mRNA /GEN=RPL23A /PROD=ribosomal protein L23a /DB_XREF=gi:4506614 /UG=Hs.184776 ribosomal protein L23a /FL=gb:U37230.1 gb:NM_000984.1" NM_000984 ribosomal protein L23a RPL23A 6147 NM_000984 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031932 // TORC2 complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203013_at NM_007265 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007265.1 /DEF=Homo sapiens suppressor of S. cerevisiae gcr2 (HSGT1), mRNA. /FEA=mRNA /GEN=HSGT1 /PROD=suppressor of S. cerevisiae gcr2 /DB_XREF=gi:6005783 /UG=Hs.19673 suppressor of S. cerevisiae gcr2 /FL=gb:BC000721.1 gb:D88208.1 gb:NM_007265.1" NM_007265 ecdysoneless homolog (Drosophila) ECD 11319 NM_001135752 /// NM_001135753 /// NM_007265 /// NR_024203 "0006110 // regulation of glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203014_x_at NM_015705 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015705.1 /DEF=Homo sapiens hypothetical protein (DJ1042K10.2), mRNA. /FEA=mRNA /GEN=DJ1042K10.2 /PROD=hypothetical protein /DB_XREF=gi:11034850 /UG=Hs.22129 hypothetical protein /FL=gb:NM_015705.1" NM_015705 small G protein signaling modulator 3 SGSM3 27352 NM_015705 /// XM_005261572 /// XM_005261573 /// XM_005261574 /// XM_005261575 /// XM_005261577 /// XM_005261579 /// XR_244369 /// XR_244370 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032483 // regulation of Rab protein signal transduction // inferred from expression pattern /// 0032486 // Rap protein signal transduction // inferred from expression pattern /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from direct assay 203015_s_at AW136988 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW136988 /FEA=EST /DB_XREF=gi:6141121 /DB_XREF=est:UI-H-BI1-acu-b-04-0-UI.s1 /CLONE=IMAGE:2715582 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 AW136988 "synovial sarcoma, X breakpoint 2 interacting protein" SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203016_s_at AK001710 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK001710.1 /DEF=Homo sapiens cDNA FLJ10848 fis, clone NT2RP4001407, highly similar to Homo sapiens mRNA for KIAA0923 protein. /FEA=mRNA /DB_XREF=gi:7023139 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1" AK001710 "synovial sarcoma, X breakpoint 2 interacting protein" SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203017_s_at R52678 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:R52678 /FEA=EST /DB_XREF=gi:814580 /DB_XREF=est:yg99c07.s1 /CLONE=IMAGE:41738 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 R52678 "synovial sarcoma, X breakpoint 2 interacting protein" SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203018_s_at AU152583 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU152583 /FEA=EST /DB_XREF=gi:11014104 /DB_XREF=est:AU152583 /CLONE=NT2RP3001245 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1 AU152583 "synovial sarcoma, X breakpoint 2 interacting protein" SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203019_x_at NM_014021 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014021.1 /DEF=Homo sapiens KIAA0923 protein (KIAA0923), mRNA. /FEA=mRNA /GEN=KIAA0923 /PROD=KIAA0923 protein /DB_XREF=gi:7662381 /UG=Hs.22587 KIAA0923 protein /FL=gb:AB023140.1 gb:NM_014021.1" NM_014021 "synovial sarcoma, X breakpoint 2 interacting protein" SSX2IP 117178 NM_001166293 /// NM_001166294 /// NM_001166295 /// NM_001166417 /// NM_014021 /// XM_005270427 /// XM_005270428 /// XM_005270429 /// XM_006710330 /// XM_006710331 /// XM_006710332 0007155 // cell adhesion // inferred from electronic annotation /// 0035020 // regulation of Rac protein signal transduction // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from mutant phenotype /// 2000145 // regulation of cell motility // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0034451 // centriolar satellite // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 203020_at NM_014857 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014857.1 /DEF=Homo sapiens KIAA0471 gene product (KIAA0471), mRNA. /FEA=mRNA /GEN=KIAA0471 /PROD=KIAA0471 gene product /DB_XREF=gi:7662143 /UG=Hs.242271 KIAA0471 gene product /FL=gb:AB007940.1 gb:NM_014857.1" NM_014857 RAB GTPase activating protein 1-like RABGAP1L 9910 NM_001035230 /// NM_001243763 /// NM_001243764 /// NM_001243765 /// NM_014857 /// XM_005245680 /// XM_005245681 /// XM_006711692 /// XM_006711693 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0017137 // Rab GTPase binding // inferred from direct assay 203021_at NM_003064 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003064.1 /DEF=Homo sapiens secretory leukocyte protease inhibitor (antileukoproteinase) (SLPI), mRNA. /FEA=mRNA /GEN=SLPI /PROD=secretory leukocyte protease inhibitor(antileukoproteinase) /DB_XREF=gi:4507064 /UG=Hs.251754 secretory leukocyte protease inhibitor (antileukoproteinase) /FL=gb:NM_003066.1 gb:AF114471.1 gb:NM_003064.1" NM_003064 secretory leukocyte peptidase inhibitor SLPI 6590 NM_003064 0006508 // proteolysis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 203022_at NM_006397 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006397.1 /DEF=Homo sapiens ribonuclease HI, large subunit (RNASEHI), mRNA. /FEA=mRNA /GEN=RNASEHI /PROD=ribonuclease HI, large subunit /DB_XREF=gi:5454009 /UG=Hs.25292 ribonuclease HI, large subunit /FL=gb:NM_006397.1" NM_006397 "ribonuclease H2, subunit A" RNASEH2A 10535 NM_006397 /// XM_006722619 "0006260 // DNA replication // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006401 // RNA catabolic process // inferred from direct assay /// 0016070 // RNA metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from direct assay /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0032299 // ribonuclease H2 complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004523 // RNA-DNA hybrid ribonuclease activity // inferred from direct assay /// 0004540 // ribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203023_at NM_016391 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016391.1 /DEF=Homo sapiens hypothetical protein (HSPC111), mRNA. /FEA=mRNA /GEN=HSPC111 /PROD=hypothetical protein /DB_XREF=gi:7705450 /UG=Hs.279918 hypothetical protein /FL=gb:AF151875.1 gb:AF161460.1 gb:AF151019.1 gb:NM_016391.1" NM_016391 NOP16 nucleolar protein NOP16 51491 NM_001256539 /// NM_001256540 /// NM_001291305 /// NM_001291306 /// NM_001291307 /// NM_001291308 /// NM_016391 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay 203024_s_at NM_020199 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020199.1 /DEF=Homo sapiens HTGN29 protein (HTGN29), mRNA. /FEA=mRNA /GEN=HTGN29 /PROD=HTGN29 protein /DB_XREF=gi:9910277 /UG=Hs.283437 HTGN29 protein /FL=gb:AF226055.1 gb:NM_020199.1" NM_020199 chromosome 5 open reading frame 15 C5orf15 56951 NM_020199 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203025_at NM_003491 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003491.1 /DEF=Homo sapiens N-acetyltransferase, homolog of S. cerevisiae ARD1 (ARD1), mRNA. /FEA=mRNA /GEN=ARD1 /PROD=N-acetyltransferase, homolog of S. cerevisiaeARD1 /DB_XREF=gi:10835056 /UG=Hs.333034 N-acetyltransferase, homolog of S. cerevisiae ARD1 /FL=gb:NM_003491.1 gb:BC000308.1" NM_003491 "N(alpha)-acetyltransferase 10, NatA catalytic subunit" NAA10 8260 NM_001256119 /// NM_001256120 /// NM_003491 0006323 // DNA packaging // traceable author statement /// 0006474 // N-terminal protein amino acid acetylation // inferred from direct assay /// 0006475 // internal protein amino acid acetylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031415 // NatA complex // inferred from direct assay "0004596 // peptide alpha-N-acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // traceable author statement /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0043022 // ribosome binding // inferred from direct assay" 203026_at NM_014872 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014872.1 /DEF=Homo sapiens KIAA0354 gene product (KIAA0354), mRNA. /FEA=mRNA /GEN=KIAA0354 /PROD=KIAA0354 gene product /DB_XREF=gi:7662073 /UG=Hs.3682 KIAA0354 gene product /FL=gb:AB002352.1 gb:NM_014872.1" NM_014872 zinc finger and BTB domain containing 5 ZBTB5 9925 NM_014872 /// XM_005251634 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203027_s_at AI189359 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI189359 /FEA=EST /DB_XREF=gi:3740568 /DB_XREF=est:qd05f07.x1 /CLONE=IMAGE:1722853 /UG=Hs.3828 mevalonate (diphospho) decarboxylase /FL=gb:U49260.1 gb:BC000011.1 gb:NM_002461.1 AI189359 mevalonate (diphospho) decarboxylase MVD 4597 NM_002461 /// XM_005256312 /// XM_006721192 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0006489 // dolichyl diphosphate biosynthetic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004163 // diphosphomevalonate decarboxylase activity // inferred from direct assay /// 0004163 // diphosphomevalonate decarboxylase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 203028_s_at NM_000101 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000101.1 /DEF=Homo sapiens cytochrome b-245, alpha polypeptide (CYBA), mRNA. /FEA=mRNA /GEN=CYBA /PROD=flavocytochrome b-558 alpha polypeptide /DB_XREF=gi:4557504 /UG=Hs.68877 cytochrome b-245, alpha polypeptide /FL=gb:M21186.1 gb:NM_000101.1" NM_000101 "cytochrome b-245, alpha polypeptide" CYBA 1535 NM_000101 "0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0003106 // negative regulation of glomerular filtration by angiotensin // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from mutant phenotype /// 0006954 // inflammatory response // inferred from mutant phenotype /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0014895 // smooth muscle hypertrophy // inferred from sequence or structural similarity /// 0017004 // cytochrome complex assembly // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045730 // respiratory burst // inferred from mutant phenotype /// 0050665 // hydrogen peroxide biosynthetic process // inferred from sequence or structural similarity /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0090382 // phagosome maturation // traceable author statement" 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // inferred from mutant phenotype /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from direct assay /// 0009055 // electron carrier activity // traceable author statement /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203029_s_at NM_002847 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002847.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), mRNA. /FEA=mRNA /GEN=PTPRN2 /PROD=protein tyrosine phosphatase, receptor type, Npolypeptide 2 /DB_XREF=gi:11386148 /UG=Hs.74624 protein tyrosine phosphatase, receptor type, N polypeptide 2 /FL=gb:NM_002847.1 gb:U66702.1 gb:AF007555.1" NM_002847 "protein tyrosine phosphatase, receptor type, N polypeptide 2" PTPRN2 5799 NM_002847 /// NM_130842 /// NM_130843 /// XM_006716075 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 203030_s_at AF007555 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF007555.1 /DEF=Homo sapiens IARreceptor-like protein-tyrosine phosphatase precursor mRNA, complete cds. /FEA=mRNA /PROD=IARreceptor-like protein-tyrosine phosphataseprecursor /DB_XREF=gi:2262074 /UG=Hs.74624 protein tyrosine phosphatase, receptor type, N polypeptide 2 /FL=gb:NM_002847.1 gb:U66702.1 gb:AF007555.1" AF007555 "protein tyrosine phosphatase, receptor type, N polypeptide 2" PTPRN2 5799 NM_002847 /// NM_130842 /// NM_130843 /// XM_006716075 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030141 // secretory granule // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 203031_s_at NM_000375 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000375.1 /DEF=Homo sapiens uroporphyrinogen III synthase (congenital erythropoietic porphyria) (UROS), mRNA. /FEA=mRNA /GEN=UROS /PROD=uroporphyrinogen III synthase /DB_XREF=gi:4557872 /UG=Hs.75593 uroporphyrinogen III synthase (congenital erythropoietic porphyria) /FL=gb:BC002573.1 gb:J03824.1 gb:NM_000375.1" NM_000375 uroporphyrinogen III synthase UROS 7390 NM_000375 /// XM_005270137 /// XM_005270138 /// XM_005270139 /// XM_005270140 /// XM_005270141 /// XM_006717960 /// XR_246103 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006780 // uroporphyrinogen III biosynthetic process // inferred from direct assay /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred by curator /// 0006783 // heme biosynthetic process // inferred from direct assay /// 0006783 // heme biosynthetic process // traceable author statement /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0071243 // cellular response to arsenic-containing substance // inferred from electronic annotation /// 0071418 // cellular response to amine stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0004852 // uroporphyrinogen-III synthase activity // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation 203032_s_at AI363836 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI363836 /FEA=EST /DB_XREF=gi:4123525 /DB_XREF=est:qy62g01.x1 /CLONE=IMAGE:2016624 /UG=Hs.75653 fumarate hydratase /FL=gb:BC003108.1 gb:M15502.1 gb:U59309.1 gb:U48857.1 gb:NM_000143.1 AI363836 fumarate hydratase FH 2271 NM_000143 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006106 // fumarate metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0045239 // tricarboxylic acid cycle enzyme complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004333 // fumarate hydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation 203033_x_at NM_000143 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000143.1 /DEF=Homo sapiens fumarate hydratase (FH), mRNA. /FEA=mRNA /GEN=FH /PROD=fumarate hydratase /DB_XREF=gi:4503716 /UG=Hs.75653 fumarate hydratase /FL=gb:BC003108.1 gb:M15502.1 gb:U59309.1 gb:U48857.1 gb:NM_000143.1" NM_000143 fumarate hydratase FH 2271 NM_000143 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006106 // fumarate metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0045239 // tricarboxylic acid cycle enzyme complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004333 // fumarate hydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation 203034_s_at NM_000990 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000990.1 /DEF=Homo sapiens ribosomal protein L27a (RPL27A), mRNA. /FEA=mRNA /GEN=RPL27A /PROD=ribosomal protein L27a /DB_XREF=gi:4506624 /UG=Hs.76064 ribosomal protein L27a /FL=gb:BC005326.1 gb:NM_000990.1 gb:U14968.1" NM_000990 "ribosomal protein L27a /// small nucleolar RNA, H/ACA box 45A" RPL27A /// SNORA45A 6157 /// 619562 NM_000990 /// NM_032650 /// NR_002580 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006744 // ubiquinone biosynthetic process // inferred from electronic annotation /// 0006744 // ubiquinone biosynthetic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009234 // menaquinone biosynthetic process // inferred from electronic annotation /// 0009234 // menaquinone biosynthetic process // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0042371 // vitamin K biosynthetic process // inferred from direct assay /// 0042371 // vitamin K biosynthetic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0004659 // prenyltransferase activity // inferred from direct assay /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016209 // antioxidant activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203035_s_at NM_006099 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006099.1 /DEF=Homo sapiens protein inhibitor of activated STAT3 (PIAS3), mRNA. /FEA=mRNA /GEN=PIAS3 /PROD=protein inhibitor of activated STAT3 /DB_XREF=gi:5174628 /UG=Hs.76578 protein inhibitor of activated STAT3 /FL=gb:BC001154.1 gb:AB021868.1 gb:NM_006099.1" NM_006099 "protein inhibitor of activated STAT, 3" PIAS3 10401 NM_006099 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from sequence or structural similarity /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0045838 // positive regulation of membrane potential // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from physical interaction 203036_s_at AI027678 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI027678 /FEA=EST /DB_XREF=gi:3245117 /DB_XREF=est:ov89e02.x1 /CLONE=IMAGE:1644506 /UG=Hs.77694 KIAA0429 gene product /FL=gb:AB007889.1 gb:NM_014751.1 AI027678 metastasis suppressor 1 MTSS1 9788 NM_001282971 /// NM_001282974 /// NM_014751 /// XM_005251111 /// XM_005251113 /// XM_005251118 /// XM_006716700 /// XM_006716701 /// XM_006716702 /// XM_006716703 /// XM_006716704 /// XM_006716705 /// XM_006716706 /// XM_006716707 0006928 // cellular component movement // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0030035 // microspike assembly // non-traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity 0001726 // ruffle // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030139 // endocytic vesicle // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203037_s_at NM_014751 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014751.1 /DEF=Homo sapiens KIAA0429 gene product (KIAA0429), mRNA. /FEA=mRNA /GEN=KIAA0429 /PROD=KIAA0429 gene product /DB_XREF=gi:7662113 /UG=Hs.77694 KIAA0429 gene product /FL=gb:AB007889.1 gb:NM_014751.1" NM_014751 metastasis suppressor 1 MTSS1 9788 NM_001282971 /// NM_001282974 /// NM_014751 /// XM_005251111 /// XM_005251113 /// XM_005251118 /// XM_006716700 /// XM_006716701 /// XM_006716702 /// XM_006716703 /// XM_006716704 /// XM_006716705 /// XM_006716706 /// XM_006716707 0006928 // cellular component movement // non-traceable author statement /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0030035 // microspike assembly // non-traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0071498 // cellular response to fluid shear stress // inferred from sequence or structural similarity /// 0072102 // glomerulus morphogenesis // inferred from sequence or structural similarity /// 0072160 // nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity /// 2001013 // epithelial cell proliferation involved in renal tubule morphogenesis // inferred from sequence or structural similarity 0001726 // ruffle // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030139 // endocytic vesicle // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203038_at NM_002844 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002844.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, K (PTPRK), mRNA. /FEA=mRNA /GEN=PTPRK /PROD=protein tyrosine phosphatase, receptor type, K /DB_XREF=gi:4506316 /UG=Hs.79005 protein tyrosine phosphatase, receptor type, K /FL=gb:L77886.1 gb:NM_002844.1" NM_002844 "protein tyrosine phosphatase, receptor type, K" PTPRK 5796 NM_001135648 /// NM_001291981 /// NM_001291982 /// NM_001291983 /// NM_001291984 /// NM_002844 /// XM_005267082 /// XM_005267085 /// XM_005267086 /// XM_006715535 /// XM_006715536 /// XM_006715537 /// XM_006715538 /// XM_006715539 /// XM_006715540 /// XM_006715541 /// XM_006725019 /// XM_006725020 /// XM_006725021 /// XM_006725022 /// XM_006725023 /// XM_006725024 /// XM_006725025 /// XM_006725026 /// XM_006725027 "0006470 // protein dephosphorylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010839 // negative regulation of keratinocyte proliferation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0034644 // cellular response to UV // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype" 0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction 203039_s_at NM_005006 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005006.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD) (NADH-coenzyme Q reductase) (NDUFS1), mRNA. /FEA=mRNA /GEN=NDUFS1 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 1(75kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4826855 /UG=Hs.8248 NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD) (NADH-coenzyme Q reductase) /FL=gb:NM_005006.1" NM_005006 "NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)" NDUFS1 4719 NM_001199981 /// NM_001199982 /// NM_001199983 /// NM_001199984 /// NM_005006 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0008637 // apoptotic mitochondrial changes // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042773 // ATP synthesis coupled electron transport // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from mutant phenotype /// 0046034 // ATP metabolic process // inferred from mutant phenotype /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation "0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation" 203040_s_at NM_000190 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000190.1 /DEF=Homo sapiens hydroxymethylbilane synthase (HMBS), mRNA. /FEA=mRNA /GEN=HMBS /PROD=hydroxymethylbilane synthase /DB_XREF=gi:4504422 /UG=Hs.82609 hydroxymethylbilane synthase /FL=gb:BC000520.1 gb:NM_000190.1" NM_000190 hydroxymethylbilane synthase HMBS 3145 NM_000190 /// NM_001024382 /// NM_001258208 /// NM_001258209 /// XM_005271531 /// XM_005271532 /// XM_005271533 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred by curator /// 0006783 // heme biosynthetic process // traceable author statement /// 0018160 // peptidyl-pyrromethane cofactor linkage // inferred from electronic annotation /// 0033014 // tetrapyrrole biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004418 // hydroxymethylbilane synthase activity // inferred from direct assay /// 0004418 // hydroxymethylbilane synthase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 203041_s_at J04183 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J04183.1 /DEF=Homo sapiens lysosomal membrane glycoprotein-2 (LAMP2), complete cds. /FEA=mRNA /GEN=LAMP2 /PROD=lysosomal membrane glycoprotein-2 /DB_XREF=gi:186929 /UG=Hs.8262 lysosomal-associated membrane protein 2 /FL=gb:J04183.1 gb:NM_002294.1" J04183 lysosomal-associated membrane protein 2 LAMP2 3920 NM_001122606 /// NM_002294 /// NM_013995 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019899 // enzyme binding // inferred from physical interaction 203042_at NM_002294 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002294.1 /DEF=Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant LAMP2A, mRNA. /FEA=mRNA /GEN=LAMP2 /PROD=lysosomal-associated membrane protein 2precursor /DB_XREF=gi:4504956 /UG=Hs.8262 lysosomal-associated membrane protein 2 /FL=gb:J04183.1 gb:NM_002294.1" NM_002294 lysosomal-associated membrane protein 2 LAMP2 3920 NM_001122606 /// NM_002294 /// NM_013995 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0050821 // protein stabilization // inferred from sequence or structural similarity 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019899 // enzyme binding // inferred from physical interaction 203043_at NM_004729 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004729.1 /DEF=Homo sapiens Ac-like transposable element (ALTE), mRNA. /FEA=mRNA /GEN=ALTE /PROD=Ac-like transposable element /DB_XREF=gi:4759257 /UG=Hs.9933 Ac-like transposable element /FL=gb:AB018328.1 gb:NM_004729.1" NM_004729 "zinc finger, BED-type containing 1" ZBED1 9189 NM_001171135 /// NM_001171136 /// NM_004729 0008152 // metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004803 // transposase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 203044_at NM_014918 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014918.1 /DEF=Homo sapiens KIAA0990 protein (KIAA0990), mRNA. /FEA=mRNA /GEN=KIAA0990 /PROD=KIAA0990 protein /DB_XREF=gi:7662433 /UG=Hs.110488 KIAA0990 protein /FL=gb:AB023207.1 gb:NM_014918.1" NM_014918 chondroitin sulfate synthase 1 CHSY1 22856 NM_014918 /// XM_006720435 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation "0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047238 // glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0050510 // N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity // inferred from electronic annotation" 203045_at NM_004148 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004148.1 /DEF=Homo sapiens ninjurin 1 (NINJ1), mRNA. /FEA=mRNA /GEN=NINJ1 /PROD=ninjurin 1 /DB_XREF=gi:4758809 /UG=Hs.11342 ninjurin 1 /FL=gb:BC004440.1 gb:U72661.1 gb:U91512.1 gb:NM_004148.1" NM_004148 ninjurin 1 NINJ1 4814 NM_004148 0007155 // cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203046_s_at NM_003920 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003920.1 /DEF=Homo sapiens timeless (Drosophila) homolog (TIMELESS), mRNA. /FEA=mRNA /GEN=TIMELESS /PROD=timeless (Drosophila) homolog /DB_XREF=gi:4507506 /UG=Hs.118631 timeless (Drosophila) homolog /FL=gb:AF098162.1 gb:AB015597.1 gb:NM_003920.1" NM_003920 timeless circadian clock TIMELESS 8914 NM_003920 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009628 // response to abiotic stimulus // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203047_at NM_005990 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005990.1 /DEF=Homo sapiens serinethreonine kinase 10 (STK10), mRNA. /FEA=mRNA /GEN=STK10 /PROD=serinethreonine kinase 10 /DB_XREF=gi:5174700 /UG=Hs.16134 serinethreonine kinase 10 /FL=gb:AB015718.1 gb:NM_005990.1 gb:AF119894.1" NM_005990 serine/threonine kinase 10 STK10 6793 NM_005990 0006468 // protein phosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0071593 // lymphocyte aggregation // inferred from electronic annotation /// 2000401 // regulation of lymphocyte migration // inferred from mutant phenotype 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042801 // polo kinase kinase activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay" 203048_s_at BE566023 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE566023 /FEA=EST /DB_XREF=gi:9809743 /DB_XREF=est:601339016F1 /CLONE=IMAGE:3681626 /UG=Hs.170098 KIAA0372 gene product /FL=gb:AB002370.1 gb:NM_014639.1 BE566023 tetratricopeptide repeat domain 37 TTC37 9652 NM_014639 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0055087 // Ski complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203049_s_at NM_014639 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014639.1 /DEF=Homo sapiens KIAA0372 gene product (KIAA0372), mRNA. /FEA=mRNA /GEN=KIAA0372 /PROD=KIAA0372 gene product /DB_XREF=gi:7662077 /UG=Hs.170098 KIAA0372 gene product /FL=gb:AB002370.1 gb:NM_014639.1" NM_014639 tetratricopeptide repeat domain 37 TTC37 9652 NM_014639 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035327 // transcriptionally active chromatin // inferred from direct assay /// 0055087 // Ski complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203050_at NM_005657 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005657.1 /DEF=Homo sapiens tumor protein p53-binding protein, 1 (TP53BP1), mRNA. /FEA=mRNA /GEN=TP53BP1 /PROD=tumor protein p53-binding protein, 1 /DB_XREF=gi:5032188 /UG=Hs.170263 tumor protein p53-binding protein, 1 /FL=gb:AF078776.1 gb:NM_005657.1" NM_005657 tumor protein p53 binding protein 1 TP53BP1 7158 NM_001141979 /// NM_001141980 /// NM_005657 /// XM_005254634 /// XM_005254635 /// XM_006720666 "0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred by curator" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay" 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from mutant phenotype /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0042162 // telomeric DNA binding // inferred from electronic annotation 203051_at NM_014952 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014952.1 /DEF=Homo sapiens KIAA0945 protein (KIAA0945), mRNA. /FEA=mRNA /GEN=KIAA0945 /PROD=KIAA0945 protein /DB_XREF=gi:7662397 /UG=Hs.22109 KIAA0945 protein /FL=gb:AB023162.1 gb:NM_014952.1" NM_014952 bromo adjacent homology domain containing 1 BAHD1 22893 NM_014952 /// XM_005254229 /// XM_005254230 /// XM_005254231 /// XM_006720436 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031507 // heterochromatin assembly // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype" 0005634 // nucleus // inferred from electronic annotation /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203052_at NM_000063 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000063.1 /DEF=Homo sapiens complement component 2 (C2), mRNA. /FEA=mRNA /GEN=C2 /PROD=complement component 2 /DB_XREF=gi:4557382 /UG=Hs.2253 complement component 2 /FL=gb:NM_000063.1" NM_000063 complement component 2 C2 717 NM_000063 /// NM_001145903 /// NM_001178063 /// NM_001282457 /// NM_001282458 /// NM_001282459 "0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // inferred from mutant phenotype /// 0006956 // complement activation // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 2000427 // positive regulation of apoptotic cell clearance // inferred from mutant phenotype" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203053_at NM_005872 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005872.1 /DEF=Homo sapiens breast carcinoma amplified sequence 2 (BCAS2), mRNA. /FEA=mRNA /GEN=BCAS2 /PROD=breast carcinoma amplified sequence 2 /DB_XREF=gi:5031652 /UG=Hs.22960 breast carcinoma amplified sequence 2 /FL=gb:BC005285.1 gb:AF081788.1 gb:AB020623.1 gb:NM_005872.1" NM_005872 breast carcinoma amplified sequence 2 BCAS2 10286 NM_005872 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203054_s_at NM_022171 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022171.1 /DEF=Homo sapiens T-cell leukemia translocation altered gene (TCTA), mRNA. /FEA=mRNA /GEN=TCTA /PROD=T-cell leukemia translocation altered gene /DB_XREF=gi:11560140 /UG=Hs.250894 T-cell leukemia translocation altered gene /FL=gb:NM_022171.1 gb:BC005157.1" NM_022171 T-cell leukemia translocation altered TCTA 6988 NM_022171 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203055_s_at NM_004706 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004706.1 /DEF=Homo sapiens Rho guanine nucleotide exchange factor (GEF) 1 (ARHGEF1), mRNA. /FEA=mRNA /GEN=ARHGEF1 /PROD=Rho guanine nucleotide exchange factor (GEF) 1 /DB_XREF=gi:4759189 /UG=Hs.252280 Rho guanine nucleotide exchange factor (GEF) 1 /FL=gb:BC005155.1 gb:NM_004706.1" NM_004706 Rho guanine nucleotide exchange factor (GEF) 1 /// uncharacterized LOC100505585 ARHGEF1 /// LOC100505585 9138 /// 100505585 NM_004706 /// NM_198977 /// NM_199002 /// XM_005259386 /// XM_005259387 /// XM_005259388 /// XM_005259389 /// XM_005259390 /// XM_006723463 /// XR_109536 /// XR_133186 /// XR_172294 0007266 // Rho protein signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050770 // regulation of axonogenesis // traceable author statement /// 0050771 // negative regulation of axonogenesis // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203056_s_at AI681013 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI681013 /FEA=EST /DB_XREF=gi:4891195 /DB_XREF=est:tx43d04.x1 /CLONE=IMAGE:2272327 /UG=Hs.26719 zinc-finger DNA-binding protein /FL=gb:D45132.1 gb:NM_015866.1 AI681013 "PR domain containing 2, with ZNF domain" PRDM2 7799 NM_001007257 /// NM_001135610 /// NM_012231 /// NM_015866 /// XM_005245992 /// XM_005245993 /// XM_005245994 /// XM_005245995 /// XM_005245996 /// XM_005245997 /// XM_005245998 /// XM_006710877 /// XM_006710878 /// XM_006710879 /// XM_006710880 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation" 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203057_s_at AV724783 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV724783 /FEA=EST /DB_XREF=gi:10829513 /DB_XREF=est:AV724783 /CLONE=HTBCEG11 /UG=Hs.26719 zinc-finger DNA-binding protein /FL=gb:D45132.1 gb:NM_015866.1 AV724783 "PR domain containing 2, with ZNF domain" PRDM2 7799 NM_001007257 /// NM_001135610 /// NM_012231 /// NM_015866 /// XM_005245992 /// XM_005245993 /// XM_005245994 /// XM_005245995 /// XM_005245996 /// XM_005245997 /// XM_005245998 /// XM_006710877 /// XM_006710878 /// XM_006710879 /// XM_006710880 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation" 0005634 // nucleus // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203058_s_at AW299958 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW299958 /FEA=EST /DB_XREF=gi:6709635 /DB_XREF=est:xs44g05.x1 /CLONE=IMAGE:2772536 /UG=Hs.274230 3-phosphoadenosine 5-phosphosulfate synthase 2 /FL=gb:AF150754.2 gb:AF313907.1 gb:AF091242.1 gb:NM_004670.1 gb:AF074331.1 gb:AF173365.1 AW299958 3'-phosphoadenosine 5'-phosphosulfate synthase 2 PAPSS2 9060 NM_001015880 /// NM_004670 0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity 203059_s_at NM_004670 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004670.1 /DEF=Homo sapiens 3-phosphoadenosine 5-phosphosulfate synthase 2 (PAPSS2), mRNA. /FEA=mRNA /GEN=PAPSS2 /PROD=3-prime-phosphoadenosine 5-prime-phosphosulfatesynthase 2 /DB_XREF=gi:4758879 /UG=Hs.274230 3-phosphoadenosine 5-phosphosulfate synthase 2 /FL=gb:AF150754.2 gb:AF313907.1 gb:AF091242.1 gb:NM_004670.1 gb:AF074331.1 gb:AF173365.1" NM_004670 3'-phosphoadenosine 5'-phosphosulfate synthase 2 PAPSS2 9060 NM_001015880 /// NM_004670 0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity 203060_s_at AF074331 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF074331.1 /DEF=Homo sapiens PAPS synthetase-2 (PAPSS2) mRNA, complete cds. /FEA=mRNA /GEN=PAPSS2 /PROD=PAPS synthetase-2 /DB_XREF=gi:5052074 /UG=Hs.274230 3-phosphoadenosine 5-phosphosulfate synthase 2 /FL=gb:AF150754.2 gb:AF313907.1 gb:AF091242.1 gb:NM_004670.1 gb:AF074331.1 gb:AF173365.1" AF074331 3'-phosphoadenosine 5'-phosphosulfate synthase 2 PAPSS2 9060 NM_001015880 /// NM_004670 0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity 203061_s_at AI673553 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI673553 /FEA=EST /DB_XREF=gi:4853284 /DB_XREF=est:we75d11.x1 /CLONE=IMAGE:2346933 /UG=Hs.277585 KIAA0170 gene product /FL=gb:D79992.1 gb:NM_014641.1 AI673553 mediator of DNA-damage checkpoint 1 MDC1 9656 NM_014641 /// XM_005249492 /// XM_005249493 /// XM_005249494 /// XM_005249497 /// XM_005249498 /// XM_005272909 /// XM_005272910 /// XM_005272911 /// XM_005272914 /// XM_005272915 /// XM_005274899 /// XM_005274900 /// XM_005274901 /// XM_005274904 /// XM_005274905 /// XM_005275065 /// XM_005275066 /// XM_005275067 /// XM_005275070 /// XM_005275071 /// XM_005275196 /// XM_005275198 /// XM_005275199 /// XM_005275200 /// XM_005275321 /// XM_005275322 /// XM_005275323 /// XM_005275326 /// XM_005275327 /// XM_005275492 /// XM_005275493 /// XM_005275494 /// XM_005275497 /// XM_005275498 /// XM_005275629 /// XM_005275630 /// XM_005275631 /// XM_005275634 /// XM_005275635 /// XM_006725856 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0070975 // FHA domain binding // inferred from physical interaction 203062_s_at NM_014641 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014641.1 /DEF=Homo sapiens KIAA0170 gene product (KIAA0170), mRNA. /FEA=mRNA /GEN=KIAA0170 /PROD=KIAA0170 gene product /DB_XREF=gi:7661965 /UG=Hs.277585 KIAA0170 gene product /FL=gb:D79992.1 gb:NM_014641.1" NM_014641 mediator of DNA-damage checkpoint 1 MDC1 9656 NM_014641 /// XM_005249492 /// XM_005249493 /// XM_005249494 /// XM_005249497 /// XM_005249498 /// XM_005272909 /// XM_005272910 /// XM_005272911 /// XM_005272914 /// XM_005272915 /// XM_005274899 /// XM_005274900 /// XM_005274901 /// XM_005274904 /// XM_005274905 /// XM_005275065 /// XM_005275066 /// XM_005275067 /// XM_005275070 /// XM_005275071 /// XM_005275196 /// XM_005275198 /// XM_005275199 /// XM_005275200 /// XM_005275321 /// XM_005275322 /// XM_005275323 /// XM_005275326 /// XM_005275327 /// XM_005275492 /// XM_005275493 /// XM_005275494 /// XM_005275497 /// XM_005275498 /// XM_005275629 /// XM_005275630 /// XM_005275631 /// XM_005275634 /// XM_005275635 /// XM_006725856 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0070975 // FHA domain binding // inferred from physical interaction 203063_at NM_014634 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014634.1 /DEF=Homo sapiens KIAA0015 gene product (KIAA0015), mRNA. /FEA=mRNA /GEN=KIAA0015 /PROD=KIAA0015 gene product /DB_XREF=gi:7661861 /UG=Hs.278441 KIAA0015 gene product /FL=gb:D13640.1 gb:NM_014634.1" NM_014634 "protein phosphatase, Mg2+/Mn2+ dependent, 1F" PPM1F 9647 NM_014634 "0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010634 // positive regulation of epithelial cell migration // inferred from mutant phenotype /// 0010811 // positive regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016576 // histone dephosphorylation // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0035690 // cellular response to drug // inferred from direct assay /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045927 // positive regulation of growth // inferred from mutant phenotype /// 0050921 // positive regulation of chemotaxis // inferred from mutant phenotype /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from mutant phenotype /// 0051894 // positive regulation of focal adhesion assembly // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay" 0005829 // cytosol // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from direct assay /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203064_s_at NM_004514 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004514.1 /DEF=Homo sapiens interleukin enhancer binding factor 1 (ILF1), mRNA. /FEA=mRNA /GEN=ILF1 /PROD=interleukin enhancer binding factor 1 /DB_XREF=gi:4758599 /UG=Hs.296281 interleukin enhancer binding factor 1 /FL=gb:U58196.1 gb:NM_004514.1" NM_004514 forkhead box K2 FOXK2 3607 NM_004514 /// NM_181430 /// NM_181431 /// XM_006722281 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0000287 // magnesium ion binding // inferred from direct assay /// 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203065_s_at NM_001753 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001753.2 /DEF=Homo sapiens caveolin 1, caveolae protein, 22kD (CAV1), mRNA. /FEA=mRNA /GEN=CAV1 /PROD=caveolin 1 /DB_XREF=gi:4580417 /UG=Hs.323469 caveolin 1, caveolae protein, 22kD /FL=gb:NM_001753.2" NM_001753 "caveolin 1, caveolae protein, 22kDa" CAV1 857 NM_001172895 /// NM_001172896 /// NM_001172897 /// NM_001753 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001960 // negative regulation of cytokine-mediated signaling pathway // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003057 // regulation of the force of heart contraction by chemical signal // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0006940 // regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from expression pattern /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from sequence or structural similarity /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019217 // regulation of fatty acid metabolic process // inferred from sequence or structural similarity /// 0019915 // lipid storage // inferred from sequence or structural similarity /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0030301 // cholesterol transport // traceable author statement /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030857 // negative regulation of epithelial cell differentiation // inferred from sequence or structural similarity /// 0030879 // mammary gland development // inferred from sequence or structural similarity /// 0031295 // T cell costimulation // inferred from direct assay /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032507 // maintenance of protein location in cell // inferred from sequence or structural similarity /// 0032570 // response to progesterone // inferred from direct assay /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033484 // nitric oxide homeostasis // inferred from sequence or structural similarity /// 0042310 // vasoconstriction // inferred from electronic annotation /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0042632 // cholesterol homeostasis // traceable author statement /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045019 // negative regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048550 // negative regulation of pinocytosis // inferred from mutant phenotype /// 0048554 // positive regulation of metalloenzyme activity // inferred from sequence or structural similarity /// 0050900 // leukocyte migration // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051001 // negative regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051480 // cytosolic calcium ion homeostasis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0051899 // membrane depolarization // inferred from sequence or structural similarity /// 0052547 // regulation of peptidase activity // inferred from sequence or structural similarity /// 0055074 // calcium ion homeostasis // inferred from sequence or structural similarity /// 0060056 // mammary gland involution // inferred from sequence or structural similarity /// 0070836 // caveola assembly // inferred from mutant phenotype /// 0071455 // cellular response to hyperoxia // inferred from mutant phenotype /// 0072584 // caveolin-mediated endocytosis // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 2000286 // receptor internalization involved in canonical Wnt signaling pathway // inferred from mutant phenotype /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from direct assay /// 0000139 // Golgi membrane // traceable author statement /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005811 // lipid particle // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from direct assay /// 0005901 // caveola // non-traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005102 // receptor binding // inferred from physical interaction /// 0005113 // patched binding // non-traceable author statement /// 0005198 // structural molecule activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // traceable author statement /// 0016504 // peptidase activator activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0032947 // protein complex scaffold // traceable author statement /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 203066_at NM_014863 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014863.1 /DEF=Homo sapiens B cell RAG associated protein (BRAG), mRNA. /FEA=mRNA /GEN=BRAG /PROD=KIAA0598 gene product /DB_XREF=gi:7662195 /UG=Hs.6079 B cell RAG associated protein /FL=gb:AB011170.1 gb:AF026477.1 gb:NM_014863.1 gb:NM_015892.1" NM_014863 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 CHST15 51363 NM_001270764 /// NM_001270765 /// NM_014863 /// NM_015892 /// XM_005269891 /// XM_005269892 /// XM_005269893 /// XM_005269894 /// XM_006717891 0005975 // carbohydrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019319 // hexose biosynthetic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0050656 // 3'-phosphoadenosine 5'-phosphosulfate binding // inferred from direct assay /// 0050659 // N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity // inferred from direct assay 203067_at NM_003477 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003477.1 /DEF=Homo sapiens Pyruvate dehydrogenase complex, lipoyl-containing component X; E3-binding protein (PDX1), mRNA. /FEA=mRNA /GEN=PDX1 /PROD=Pyruvate dehydrogenase complex,lipoyl-containing component X /DB_XREF=gi:4505698 /UG=Hs.74642 Pyruvate dehydrogenase complex, lipoyl-containing component X; E3-binding protein /FL=gb:AF001437.1 gb:U82328.1 gb:NM_003477.1" NM_003477 "pyruvate dehydrogenase complex, component X" PDHX 8050 NM_001135024 /// NM_001166158 /// NM_003477 0006090 // pyruvate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010510 // regulation of acetyl-CoA biosynthetic process from pyruvate // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement "0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation" 203068_at NM_014851 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014851.1 /DEF=Homo sapiens KIAA0469 gene product (KIAA0469), mRNA. /FEA=mRNA /GEN=KIAA0469 /PROD=KIAA0469 gene product /DB_XREF=gi:7662139 /UG=Hs.7764 KIAA0469 gene product /FL=gb:AB007938.1 gb:NM_014851.1" NM_014851 kelch-like family member 21 KLHL21 9903 NM_014851 /// XM_005263542 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0035853 // chromosome passenger complex localization to spindle midzone // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005827 // polar microtubule // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 203069_at NM_014849 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014849.1 /DEF=Homo sapiens KIAA0736 gene product (KIAA0736), mRNA. /FEA=mRNA /GEN=KIAA0736 /PROD=KIAA0736 gene product /DB_XREF=gi:7662271 /UG=Hs.7979 KIAA0736 gene product /FL=gb:AB018279.1 gb:NM_014849.1" NM_014849 synaptic vesicle glycoprotein 2A SV2A 9900 NM_001278719 /// NM_014849 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 203070_at NM_004636 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:NM_004636.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B (SEMA3B), mRNA. /FEA=mRNA /GEN=SEMA3B /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3B /DB_XREF=gi:4759091 /UG=Hs.82222 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B /FL=gb:NM_004636.1 gb:U28369.1" NM_004636 "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B" SEMA3B 7869 NM_001005914 /// NM_001290060 /// NM_001290061 /// NM_001290062 /// NM_001290063 /// NM_004636 /// NR_110697 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation 203071_at NM_004636 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004636.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B (SEMA3B), mRNA. /FEA=mRNA /GEN=SEMA3B /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3B /DB_XREF=gi:4759091 /UG=Hs.82222 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B /FL=gb:NM_004636.1 gb:U28369.1" NM_004636 "microRNA 6872 /// sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B" MIR6872 /// SEMA3B 7869 /// 102465526 NM_001005914 /// NM_001290060 /// NM_001290061 /// NM_001290062 /// NM_001290063 /// NM_004636 /// NR_106932 /// NR_110697 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation 203072_at NM_004998 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004998.1 /DEF=Homo sapiens myosin IC (MYO1C), mRNA. /FEA=mRNA /GEN=MYO1C /PROD=myosin IC /DB_XREF=gi:4826843 /UG=Hs.82251 myosin IC /FL=gb:NM_004998.1 gb:U14391.1" NM_004998 myosin IE MYO1E 4643 NM_004998 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0003094 // glomerular filtration // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006200 // ATP catabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030048 // actin filament-based movement // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016459 // myosin complex // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000146 // microfilament motor activity // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0042623 // ATPase activity, coupled // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay" 203073_at NM_007357 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007357.1 /DEF=Homo sapiens low density lipoprotein receptor defect C complementing (LDLC), mRNA. /FEA=mRNA /GEN=LDLC /PROD=low density lipoprotein receptor defect Ccomplementing /DB_XREF=gi:6678675 /UG=Hs.82399 low density lipoprotein receptor defect C complementing /FL=gb:NM_007357.1" NM_007357 component of oligomeric golgi complex 2 COG2 22796 NM_001145036 /// NM_007357 0006486 // protein glycosylation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0009312 // oligosaccharide biosynthetic process // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0017119 // Golgi transport complex // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from mutant phenotype /// 0032403 // protein complex binding // inferred from electronic annotation 203074_at NM_001630 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001630.1 /DEF=Homo sapiens annexin A8 (ANXA8), mRNA. /FEA=mRNA /GEN=ANXA8 /PROD=annexin VIII /DB_XREF=gi:4502112 /UG=Hs.87268 annexin A8 /FL=gb:BC004376.1 gb:M81844.1 gb:NM_001630.1" NM_001630 annexin A8 /// annexin A8-like 1 ANXA8 /// ANXA8L1 653145 /// 728113 NM_001039801 /// NM_001040084 /// NM_001098845 /// NM_001271702 /// NM_001271703 /// NM_001278923 /// NM_001278924 /// NM_001630 /// XM_006717951 /// XR_246202 /// XR_428714 0007032 // endosome organization // inferred from mutant phenotype /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from mutant phenotype /// 1900004 // negative regulation of serine-type endopeptidase activity // inferred from direct assay /// 1900138 // negative regulation of phospholipase A2 activity // inferred from direct assay 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from direct assay /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay" 203075_at AW151617 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW151617 /FEA=EST /DB_XREF=gi:6199515 /DB_XREF=est:xf66g01.x1 /CLONE=IMAGE:2623056 /UG=Hs.82483 MAD (mothers against decapentaplegic, Drosophila) homolog 2 /FL=gb:U59911.1 gb:U68018.1 gb:U65019.1 gb:AF027964.1 gb:NM_005901.1" AW151617 SMAD family member 2 SMAD2 4087 NM_001003652 /// NM_001135937 /// NM_005901 /// XM_005258259 /// XM_006722451 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0007369 // gastrulation // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031016 // pancreas development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1900224 // positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay "0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction" 203076_s_at U65019 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U65019.1 /DEF=Human MAD-related protein 2 (MADR2) mRNA, complete cds. /FEA=mRNA /GEN=MADR2 /PROD=MAD-related protein 2 /DB_XREF=gi:1575529 /UG=Hs.82483 MAD (mothers against decapentaplegic, Drosophila) homolog 2 /FL=gb:U59911.1 gb:U68018.1 gb:U65019.1 gb:AF027964.1 gb:NM_005901.1" U65019 SMAD family member 2 SMAD2 4087 NM_001003652 /// NM_001135937 /// NM_005901 /// XM_005258259 /// XM_006722451 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0007369 // gastrulation // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031016 // pancreas development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1900224 // positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay "0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction" 203077_s_at NM_005901 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005901.1 /DEF=Homo sapiens MAD (mothers against decapentaplegic, Drosophila) homolog 2 (MADH2), mRNA. /FEA=mRNA /GEN=MADH2 /PROD=MAD (mothers against decapentaplegic,Drosophila) homolog 2 /DB_XREF=gi:5174510 /UG=Hs.82483 MAD (mothers against decapentaplegic, Drosophila) homolog 2 /FL=gb:U59911.1 gb:U68018.1 gb:U65019.1 gb:AF027964.1 gb:NM_005901.1" NM_005901 SMAD family member 2 SMAD2 4087 NM_001003652 /// NM_001135937 /// NM_005901 /// XM_005258259 /// XM_006722451 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001706 // endoderm formation // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007352 // zygotic specification of dorsal/ventral axis // inferred from mutant phenotype /// 0007369 // gastrulation // traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031016 // pancreas development // inferred from electronic annotation /// 0031053 // primary miRNA processing // traceable author statement /// 0032924 // activin receptor signaling pathway // inferred from mutant phenotype /// 0035265 // organ growth // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038092 // nodal signaling pathway // inferred from mutant phenotype /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048340 // paraxial mesoderm morphogenesis // inferred from sequence or structural similarity /// 0048589 // developmental growth // inferred from electronic annotation /// 0048617 // embryonic foregut morphogenesis // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 1900224 // positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0032444 // activin responsive factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0071141 // SMAD protein complex // inferred from direct assay /// 0071144 // SMAD2-SMAD3 protein complex // inferred from direct assay "0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005160 // transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034713 // type I transforming growth factor beta receptor binding // inferred from physical interaction /// 0035326 // enhancer binding // inferred by curator /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction /// 0070412 // R-SMAD binding // inferred from physical interaction" 203078_at U83410 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:U83410.1 /DEF=Human CUL-2 (cul-2) mRNA, complete cds. /FEA=mRNA /GEN=cul-2 /PROD=CUL-2 /DB_XREF=gi:1923242 /UG=Hs.82919 cullin 2 /FL=gb:U83410.1 gb:NM_003591.1 gb:AF126404.1" U83410 cullin 2 CUL2 8453 NM_001198777 /// NM_001198778 /// NM_001198779 /// NM_003591 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 203079_s_at NM_003591 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003591.1 /DEF=Homo sapiens cullin 2 (CUL2), mRNA. /FEA=mRNA /GEN=CUL2 /PROD=cullin 2 /DB_XREF=gi:4503162 /UG=Hs.82919 cullin 2 /FL=gb:U83410.1 gb:NM_003591.1 gb:AF126404.1" NM_003591 cullin 2 CUL2 8453 NM_001198777 /// NM_001198778 /// NM_001198779 /// NM_003591 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0071456 // cellular response to hypoxia // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030891 // VCB complex // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031462 // Cul2-RING ubiquitin ligase complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation 203080_s_at NM_013450 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013450.1 /DEF=Homo sapiens bromodomain adjacent to zinc finger domain, 2B (BAZ2B), mRNA. /FEA=mRNA /GEN=BAZ2B /PROD=bromodomain adjacent to zinc finger domain, 2B /DB_XREF=gi:7304922 /UG=Hs.8383 bromodomain adjacent to zinc finger domain, 2B /FL=gb:AB032255.1 gb:NM_013450.1" NM_013450 "bromodomain adjacent to zinc finger domain, 2B" BAZ2B 29994 NM_001289975 /// NM_013450 /// NR_110586 /// XM_005246488 /// XM_005246489 /// XM_005246492 /// XM_005246497 /// XM_005246500 /// XM_006712461 /// XM_006712462 /// XM_006712463 /// XM_006712464 /// XM_006712465 /// XM_006712466 /// XM_006712467 /// XM_006712468 /// XM_006712469 /// XM_006712470 /// XM_006712471 /// XM_006712472 /// XM_006712473 /// XM_006712474 /// XR_425476 /// XR_427178 /// XR_431488 "0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203081_at NM_020248 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020248.1 /DEF=Homo sapiens beta-catenin-interacting protein ICAT (LOC56998), mRNA. /FEA=mRNA /GEN=LOC56998 /PROD=beta-catenin-interacting protein ICAT /DB_XREF=gi:9910389 /UG=Hs.99816 beta-catenin-interacting protein ICAT /FL=gb:AB021262.1 gb:NM_020248.1" NM_020248 "catenin, beta interacting protein 1" CTNNBIP1 56998 NM_001012329 /// NM_020248 /// XM_006710779 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0002528 // regulation of vascular permeability involved in acute inflammatory response // inferred from mutant phenotype /// 0009952 // anterior/posterior pattern specification // not recorded /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // not recorded /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045657 // positive regulation of monocyte differentiation // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0060633 // negative regulation of transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0072201 // negative regulation of mesenchymal cell proliferation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0070016 // armadillo repeat domain binding // inferred from physical interaction 203082_at NM_014753 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014753.1 /DEF=Homo sapiens KIAA0187 gene product (KIAA0187), mRNA. /FEA=mRNA /GEN=KIAA0187 /PROD=KIAA0187 gene product /DB_XREF=gi:7661979 /UG=Hs.10848 KIAA0187 gene product /FL=gb:D80009.1 gb:NM_014753.1" NM_014753 BMS1 ribosome biogenesis factor BMS1 9790 NM_014753 /// XM_005271846 /// XM_005271847 /// XM_005271848 /// XM_005271849 /// XM_006718081 /// XR_246522 /// XR_428728 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203083_at NM_003247 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003247.1 /DEF=Homo sapiens thrombospondin 2 (THBS2), mRNA. /FEA=mRNA /GEN=THBS2 /PROD=thrombospondin 2 /DB_XREF=gi:4507486 /UG=Hs.108623 thrombospondin 2 /FL=gb:L12350.1 gb:NM_003247.1" NM_003247 thrombospondin 2 THBS2 7058 NM_003247 0007155 // cell adhesion // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation 203084_at NM_000660 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000660.1 /DEF=Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA. /FEA=mRNA /GEN=TGFB1 /PROD=transforming growth factor, beta 1 /DB_XREF=gi:10863872 /UG=Hs.1103 transforming growth factor, beta 1 /FL=gb:NM_000660.1 gb:BC000125.1 gb:BC001180.1 gb:M38449.1" NM_000660 "transforming growth factor, beta 1" TGFB1 7040 NM_000660 "0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // traceable author statement /// 0002460 // adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains // inferred from electronic annotation /// 0002513 // tolerance induction to self antigen // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from direct assay /// 0006796 // phosphate-containing compound metabolic process // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007492 // endoderm development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009817 // defense response to fungus, incompatible interaction // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred by curator /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // non-traceable author statement /// 0010742 // macrophage derived foam cell differentiation // inferred by curator /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016202 // regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0019058 // viral life cycle // traceable author statement /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030334 // regulation of cell migration // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from expression pattern /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031536 // positive regulation of exit from mitosis // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0032943 // mononuclear cell proliferation // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0032967 // positive regulation of collagen biosynthetic process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042306 // regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043932 // ossification involved in bone remodeling // inferred from expression pattern /// 0045066 // regulatory T cell differentiation // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046732 // active induction of host immune response by virus // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0048535 // lymph node development // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from direct assay /// 0048839 // inner ear development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0051101 // regulation of DNA binding // inferred from sequence or structural similarity /// 0051152 // positive regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060312 // regulation of blood vessel remodeling // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060751 // branch elongation involved in mammary gland duct branching // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061035 // regulation of cartilage development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from direct assay /// 1901203 // positive regulation of extracellular matrix assembly // inferred by curator /// 1901666 // positive regulation of NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 2000628 // regulation of miRNA metabolic process // inferred from direct assay /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0009986 // cell surface // inferred from mutant phenotype /// 0030141 // secretory granule // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203085_s_at BC000125 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000125.1 /DEF=Homo sapiens, Similar to transforming growth factor, beta 1, clone MGC:3119, mRNA, complete cds. /FEA=mRNA /PROD=Similar to transforming growth factor, beta 1 /DB_XREF=gi:12652748 /UG=Hs.1103 transforming growth factor, beta 1 /FL=gb:NM_000660.1 gb:BC000125.1 gb:BC001180.1 gb:M38449.1" BC000125 "transforming growth factor, beta 1" TGFB1 7040 NM_000660 "0000060 // protein import into nucleus, translocation // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from mutant phenotype /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from electronic annotation /// 0001775 // cell activation // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002028 // regulation of sodium ion transport // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // traceable author statement /// 0002460 // adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains // inferred from electronic annotation /// 0002513 // tolerance induction to self antigen // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from direct assay /// 0006796 // phosphate-containing compound metabolic process // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007182 // common-partner SMAD protein phosphorylation // inferred from direct assay /// 0007183 // SMAD protein complex assembly // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007435 // salivary gland morphogenesis // inferred from expression pattern /// 0007492 // endoderm development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009749 // response to glucose // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009817 // defense response to fungus, incompatible interaction // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred by curator /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010718 // positive regulation of epithelial to mesenchymal transition // non-traceable author statement /// 0010742 // macrophage derived foam cell differentiation // inferred by curator /// 0010763 // positive regulation of fibroblast migration // inferred from direct assay /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010936 // negative regulation of macrophage cytokine production // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016202 // regulation of striated muscle tissue development // inferred from sequence or structural similarity /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019049 // evasion or tolerance of host defenses by virus // inferred from direct assay /// 0019058 // viral life cycle // traceable author statement /// 0022408 // negative regulation of cell-cell adhesion // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030214 // hyaluronan catabolic process // inferred from direct assay /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030334 // regulation of cell migration // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030501 // positive regulation of bone mineralization // inferred from expression pattern /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031334 // positive regulation of protein complex assembly // inferred from direct assay /// 0031536 // positive regulation of exit from mitosis // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0032740 // positive regulation of interleukin-17 production // inferred from direct assay /// 0032801 // receptor catabolic process // inferred from direct assay /// 0032930 // positive regulation of superoxide anion generation // inferred from direct assay /// 0032943 // mononuclear cell proliferation // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0032967 // positive regulation of collagen biosynthetic process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from direct assay /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0035066 // positive regulation of histone acetylation // inferred from electronic annotation /// 0035307 // positive regulation of protein dephosphorylation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042306 // regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0042482 // positive regulation of odontogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043011 // myeloid dendritic cell differentiation // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043932 // ossification involved in bone remodeling // inferred from expression pattern /// 0045066 // regulatory T cell differentiation // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from direct assay /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045662 // negative regulation of myoblast differentiation // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046732 // active induction of host immune response by virus // traceable author statement /// 0048298 // positive regulation of isotype switching to IgA isotypes // inferred from direct assay /// 0048535 // lymph node development // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048642 // negative regulation of skeletal muscle tissue development // inferred from direct assay /// 0048839 // inner ear development // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from direct assay /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051098 // regulation of binding // inferred from sequence or structural similarity /// 0051101 // regulation of DNA binding // inferred from sequence or structural similarity /// 0051152 // positive regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051280 // negative regulation of release of sequestered calcium ion into cytosol // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060312 // regulation of blood vessel remodeling // inferred by curator /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060364 // frontal suture morphogenesis // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060751 // branch elongation involved in mammary gland duct branching // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0061035 // regulation of cartilage development // inferred from electronic annotation /// 0070306 // lens fiber cell differentiation // inferred from electronic annotation /// 0070723 // response to cholesterol // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0085029 // extracellular matrix assembly // inferred from direct assay /// 0090190 // positive regulation of branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 1900126 // negative regulation of hyaluronan biosynthetic process // inferred from direct assay /// 1901203 // positive regulation of extracellular matrix assembly // inferred by curator /// 1901666 // positive regulation of NAD+ ADP-ribosyltransferase activity // inferred from direct assay /// 2000628 // regulation of miRNA metabolic process // inferred from direct assay /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0009986 // cell surface // inferred from mutant phenotype /// 0030141 // secretory granule // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0072562 // blood microparticle // inferred from direct assay 0001948 // glycoprotein binding // inferred from physical interaction /// 0003823 // antigen binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005125 // cytokine activity // traceable author statement /// 0005160 // transforming growth factor beta receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203086_at BE872563 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE872563 /FEA=EST /DB_XREF=gi:10321339 /DB_XREF=est:601451167F1 /CLONE=IMAGE:3854969 /UG=Hs.113319 kinesin heavy chain member 2 /FL=gb:NM_004520.1 BE872563 kinesin heavy chain member 2A KIF2A 3796 NM_001098511 /// NM_001243952 /// NM_001243953 /// NM_004520 0000278 // mitotic cell cycle // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203087_s_at NM_004520 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004520.1 /DEF=Homo sapiens kinesin heavy chain member 2 (KIF2), mRNA. /FEA=mRNA /GEN=KIF2 /PROD=kinesin heavy chain member 2 /DB_XREF=gi:4758643 /UG=Hs.113319 kinesin heavy chain member 2 /FL=gb:NM_004520.1" NM_004520 kinesin heavy chain member 2A KIF2A 3796 NM_001098511 /// NM_001243952 /// NM_001243953 /// NM_004520 0000278 // mitotic cell cycle // traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203088_at NM_006329 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006329.1 /DEF=Homo sapiens fibulin 5 (FBLN5), mRNA. /FEA=mRNA /GEN=FBLN5 /PROD=fibulin 5 /DB_XREF=gi:5453649 /UG=Hs.11494 fibulin 5 /FL=gb:AF093118.1 gb:AF112152.1 gb:NM_006329.1" NM_006329 fibulin 5 FBLN5 10516 NM_006329 /// XM_005267267 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from sequence or structural similarity /// 2000121 // regulation of removal of superoxide radicals // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071953 // elastic fiber // inferred from sequence or structural similarity 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 203089_s_at NM_013247 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013247.1 /DEF=Homo sapiens HtrA-like serine protease (OMI), mRNA. /FEA=mRNA /GEN=OMI /PROD=HtrA-like serine protease /DB_XREF=gi:7019476 /UG=Hs.115721 HtrA-like serine protease /FL=gb:BC000096.1 gb:AF020760.2 gb:NM_013247.1 gb:AF141305.1" NM_013247 HtrA serine peptidase 2 HTRA2 27429 NM_013247 /// NM_145074 /// XM_005264266 0006508 // proteolysis // inferred from mutant phenotype /// 0006508 // proteolysis // traceable author statement /// 0006672 // ceramide metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0009635 // response to herbicide // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0016540 // protein autoprocessing // traceable author statement /// 0019742 // pentacyclic triterpenoid metabolic process // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from direct assay /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0048666 // neuron development // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097194 // execution phase of apoptosis // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001269 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from mutant phenotype 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from mutant phenotype /// 0005739 // mitochondrion // traceable author statement /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from mutant phenotype /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 203090_at NM_006923 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006923.1 /DEF=Homo sapiens stromal cell-derived factor 2 (SDF2), mRNA. /FEA=mRNA /GEN=SDF2 /PROD=stromal cell-derived factor 2 /DB_XREF=gi:5902073 /UG=Hs.118684 stromal cell-derived factor 2 /FL=gb:BC000500.1 gb:BC001406.1 gb:D50645.1 gb:NM_006923.1" NM_006923 stromal cell-derived factor 2 SDF2 6388 NM_006923 /// NR_045585 0006486 // protein glycosylation // traceable author statement /// 0035269 // protein O-linked mannosylation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004169 // dolichyl-phosphate-mannose-protein mannosyltransferase activity // traceable author statement 203091_at NM_003902 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003902.1 /DEF=Homo sapiens far upstream element (FUSE) binding protein 1 (FUBP1), mRNA. /FEA=mRNA /GEN=FUBP1 /PROD=far upstream element-binding protein /DB_XREF=gi:4503800 /UG=Hs.118962 far upstream element (FUSE) binding protein 1 /FL=gb:NM_003902.1 gb:U05040.1" NM_003902 far upstream element (FUSE) binding protein 1 FUBP1 8880 NM_003902 /// XM_005271309 /// XM_006711021 /// XM_006711022 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203092_at AF026030 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF026030.1 /DEF=Homo sapiens putative mitochondrial inner membrane protein import receptor (hTIM44) mRNA, nuclear gene encoding mitochondrial protein, complete cds. /FEA=mRNA /GEN=hTIM44 /PROD=putative mitochondrial inner membrane proteinimport receptor /DB_XREF=gi:4103601 /UG=Hs.123178 translocase of inner mitochondrial membrane 44 (yeast) homolog /FL=gb:AF026030.1 gb:NM_006351.1" AF026030 translocase of inner mitochondrial membrane 44 homolog (yeast) TIMM44 10469 NM_006351 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203093_s_at NM_006351 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006351.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 44 (yeast) homolog (TIM44), mRNA. /FEA=mRNA /GEN=TIM44 /PROD=translocase of inner mitochondrial membrane 44(yeast) homolog /DB_XREF=gi:5454123 /UG=Hs.123178 translocase of inner mitochondrial membrane 44 (yeast) homolog /FL=gb:AF026030.1 gb:NM_006351.1" NM_006351 translocase of inner mitochondrial membrane 44 homolog (yeast) TIMM44 10469 NM_006351 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203094_at NM_014628 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014628.1 /DEF=Homo sapiens gene predicted from cDNA with a complete coding sequence (KIAA0110), mRNA. /FEA=mRNA /GEN=KIAA0110 /PROD=gene predicted from cDNA with a complete codingsequence /DB_XREF=gi:7661917 /UG=Hs.124 gene predicted from cDNA with a complete coding sequence /FL=gb:BC002904.1 gb:D14811.1 gb:NM_014628.1" NM_014628 MAD2L1 binding protein MAD2L1BP 9587 NM_001003690 /// NM_014628 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007096 // regulation of exit from mitosis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203095_at NM_002453 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002453.1 /DEF=Homo sapiens mitochondrial translational initiation factor 2 (MTIF2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MTIF2 /PROD=mitochondrial translational initiation factor 2precursor /DB_XREF=gi:4505276 /UG=Hs.149894 mitochondrial translational initiation factor 2 /FL=gb:NM_002453.1 gb:L34600.1" NM_002453 mitochondrial translational initiation factor 2 MTIF2 4528 NM_001005369 /// NM_002453 /// XM_005264335 /// XM_006712023 /// XM_006712024 0001732 // formation of translation initiation complex // inferred from sequence or structural similarity /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from sequence or structural similarity /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032790 // ribosome disassembly // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred by curator /// 0005739 // mitochondrion // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // inferred from sequence or structural similarity /// 0043024 // ribosomal small subunit binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay" 203096_s_at BF439282 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF439282 /FEA=EST /DB_XREF=gi:11451799 /DB_XREF=est:nab62c11.x1 /CLONE=IMAGE:3272444 /UG=Hs.154545 PDZ domain containing guanine nucleotide exchange factor(GEF)1 /FL=gb:AB002311.1 gb:NM_014247.1 BF439282 Rap guanine nucleotide exchange factor (GEF) 2 RAPGEF2 9693 NM_014247 /// XM_005263358 /// XM_005263359 /// XM_005263360 /// XM_005263361 /// XM_006714420 /// XM_006714421 /// XM_006714422 0000165 // MAPK cascade // non-traceable author statement /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0021591 // ventricular system development // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0048022 // negative regulation of melanin biosynthetic process // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030552 // cAMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from direct assay /// 0046582 // Rap GTPase activator activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from direct assay 203097_s_at NM_014247 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014247.1 /DEF=Homo sapiens PDZ domain containing guanine nucleotide exchange factor(GEF)1 (PDZ-GEF1), mRNA. /FEA=mRNA /GEN=PDZ-GEF1 /PROD=PDZ domain containing guanine nucleotideexchange factor(GEF)1 /DB_XREF=gi:7657260 /UG=Hs.154545 PDZ domain containing guanine nucleotide exchange factor(GEF)1 /FL=gb:AB002311.1 gb:NM_014247.1" NM_014247 Rap guanine nucleotide exchange factor (GEF) 2 RAPGEF2 9693 NM_014247 /// XM_005263358 /// XM_005263359 /// XM_005263360 /// XM_005263361 /// XM_006714420 /// XM_006714421 /// XM_006714422 0000165 // MAPK cascade // non-traceable author statement /// 0001568 // blood vessel development // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0019933 // cAMP-mediated signaling // inferred from direct assay /// 0019933 // cAMP-mediated signaling // non-traceable author statement /// 0021591 // ventricular system development // inferred from sequence or structural similarity /// 0021884 // forebrain neuron development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from direct assay /// 0031547 // brain-derived neurotrophic factor receptor signaling pathway // inferred from sequence or structural similarity /// 0032092 // positive regulation of protein binding // inferred from sequence or structural similarity /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032486 // Rap protein signal transduction // inferred from mutant phenotype /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // traceable author statement /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0048022 // negative regulation of melanin biosynthetic process // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0061028 // establishment of endothelial barrier // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071880 // adenylate cyclase-activating adrenergic receptor signaling pathway // inferred from direct assay /// 1901888 // regulation of cell junction assembly // inferred from mutant phenotype /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000670 // positive regulation of dendritic cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity /// 2001224 // positive regulation of neuron migration // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005088 // Ras guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0017034 // Rap guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019992 // diacylglycerol binding // non-traceable author statement /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030552 // cAMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from direct assay /// 0046582 // Rap GTPase activator activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from direct assay 203098_at AL050164 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL050164.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586C1622 (from clone DKFZp586C1622); partial cds. /FEA=mRNA /GEN=DKFZp586C1622 /PROD=hypothetical protein /DB_XREF=gi:4884378 /UG=Hs.16081 chromodomain protein, Y chromosome-like /FL=gb:AF081258.1 gb:AF081259.1 gb:NM_004824.1" AL050164 "chromodomain protein, Y-like" CDYL 9425 NM_001143970 /// NM_001143971 /// NM_004824 /// NM_170752 /// NR_026590 /// XM_006715272 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay "0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay" 203099_s_at AF081258 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF081258.1 /DEF=Homo sapiens testis-specific chromodomain Y-like protein (CDYL) mRNA, alternatively processed, complete cds. /FEA=mRNA /GEN=CDYL /PROD=testis-specific chromodomain Y-like protein /DB_XREF=gi:4558755 /UG=Hs.16081 chromodomain protein, Y chromosome-like /FL=gb:AF081258.1 gb:AF081259.1 gb:NM_004824.1" AF081258 "chromodomain protein, Y-like" CDYL 9425 NM_001143970 /// NM_001143971 /// NM_004824 /// NM_170752 /// NR_026590 /// XM_006715272 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay "0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay" 203100_s_at NM_004824 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004824.1 /DEF=Homo sapiens chromodomain protein, Y chromosome-like (CDYL), mRNA. /FEA=mRNA /GEN=CDYL /PROD=chromodomain protein, Y chromosome-like /DB_XREF=gi:4757969 /UG=Hs.16081 chromodomain protein, Y chromosome-like /FL=gb:AF081258.1 gb:AF081259.1 gb:NM_004824.1" NM_004824 "chromodomain protein, Y-like" CDYL 9425 NM_001143970 /// NM_001143971 /// NM_004824 /// NM_170752 /// NR_026590 /// XM_006715272 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay "0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay" 203101_s_at AW103265 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW103265 /FEA=EST /DB_XREF=gi:6073916 /DB_XREF=est:xd67b03.x1 /CLONE=IMAGE:2602637 /UG=Hs.172195 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase /FL=gb:NM_002408.2" AW103265 "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase" MGAT2 4247 NM_001015883 /// NM_002408 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0009311 // oligosaccharide metabolic process // traceable author statement /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation "0008455 // alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation" 203102_s_at NM_002408 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002408.2 /DEF=Homo sapiens mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT2), mRNA. /FEA=mRNA /GEN=MGAT2 /PROD=alpha-1,6-mannosyl-glycoproteinbeta-1,2-N-acetylglucosaminyltransferase /DB_XREF=gi:6031183 /UG=Hs.172195 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase /FL=gb:NM_002408.2" NM_002408 "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase" MGAT2 4247 NM_001015883 /// NM_002408 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0009311 // oligosaccharide metabolic process // traceable author statement /// 0009312 // oligosaccharide biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation "0008455 // alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation" 203103_s_at NM_014502 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014502.1 /DEF=Homo sapiens nuclear matrix protein NMP200 related to splicing factor PRP19 (NMP200), mRNA. /FEA=mRNA /GEN=NMP200 /PROD=nuclear matrix protein NMP200 related tosplicing factor PRP19 /DB_XREF=gi:7657380 /UG=Hs.173980 nuclear matrix protein NMP200 related to splicing factor PRP19 /FL=gb:NM_014502.1" NM_014502 pre-mRNA processing factor 19 PRPF19 27339 NM_014502 "0000209 // protein polyubiquitination // inferred from direct assay /// 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048026 // positive regulation of mRNA splicing, via spliceosome // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation" 0000151 // ubiquitin ligase complex // inferred from electronic annotation /// 0000974 // Prp19 complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0034450 // ubiquitin-ubiquitin ligase activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 203104_at NM_005211 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005211.1 /DEF=Homo sapiens colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog (CSF1R), mRNA. /FEA=mRNA /GEN=CSF1R /PROD=colony stimulating factor 1 receptor, formerlyMcDonough feline sarcoma viral (v-fms) oncogene homolog /DB_XREF=gi:4885158 /UG=Hs.174142 colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog /FL=gb:NM_005211.1" NM_005211 colony stimulating factor 1 receptor CSF1R 1436 NM_001288705 /// NM_005211 /// NR_109969 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030224 // monocyte differentiation // traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from sequence or structural similarity /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from mutant phenotype /// 0038145 // macrophage colony-stimulating factor signaling pathway // inferred from electronic annotation /// 0038145 // macrophage colony-stimulating factor signaling pathway // inferred from mutant phenotype /// 0038145 // macrophage colony-stimulating factor signaling pathway // traceable author statement /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0045087 // innate immune response // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045217 // cell-cell junction maintenance // inferred from mutant phenotype /// 0046488 // phosphatidylinositol metabolic process // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from sequence or structural similarity /// 0060603 // mammary gland duct morphogenesis // traceable author statement /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0090197 // positive regulation of chemokine secretion // inferred from mutant phenotype /// 2000147 // positive regulation of cell motility // inferred from mutant phenotype /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005011 // macrophage colony-stimulating factor receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from direct assay /// 0019955 // cytokine binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity" 203105_s_at NM_012062 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012062.1 /DEF=Homo sapiens dynamin 1-like (DNM1L), transcript variant 1, mRNA. /FEA=mRNA /GEN=DNM1L /PROD=dynamin 1-like protein, isoform 1 /DB_XREF=gi:6996004 /UG=Hs.180628 dynamin 1-like /FL=gb:AF000430.1 gb:AB006965.1 gb:NM_012062.1" NM_012062 dynamin 1-like DNM1L 10059 NM_001278463 /// NM_001278464 /// NM_001278465 /// NM_001278466 /// NM_005690 /// NM_012062 /// NM_012063 /// XM_005253282 /// XM_005253283 0000266 // mitochondrial fission // inferred from direct assay /// 0000266 // mitochondrial fission // inferred from mutant phenotype /// 0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0003374 // dynamin polymerization involved in mitochondrial fission // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0010821 // regulation of mitochondrion organization // inferred from mutant phenotype /// 0012501 // programmed cell death // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from direct assay /// 0016559 // peroxisome fission // inferred from mutant phenotype /// 0032459 // regulation of protein oligomerization // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from direct assay /// 0061025 // membrane fusion // inferred from direct assay /// 0070266 // necroptotic process // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0090141 // positive regulation of mitochondrial fission // traceable author statement /// 0090149 // membrane fission involved in mitochondrial fission // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 1900063 // regulation of peroxisome organization // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay 203106_s_at NM_014396 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014396.1 /DEF=Homo sapiens vacuolar protein sorting 41 (yeast homolog) (VPS41), mRNA. /FEA=mRNA /GEN=VPS41 /PROD=vacuolar protein sorting 41 (yeast homolog) /DB_XREF=gi:7657676 /UG=Hs.180941 vacuolar protein sorting 41 (yeast homolog) /FL=gb:U87309.1 gb:NM_014396.1" NM_014396 vacuolar protein sorting 41 homolog (S. cerevisiae) VPS41 27072 NM_014396 /// NM_080631 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048193 // Golgi vesicle transport // inferred from mutant phenotype 0005765 // lysosomal membrane // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // inferred from mutant phenotype /// 0005829 // cytosol // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030897 // HOPS complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203107_x_at NM_002952 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002952.1 /DEF=Homo sapiens ribosomal protein S2 (RPS2), mRNA. /FEA=mRNA /GEN=RPS2 /PROD=ribosomal protein S2 /DB_XREF=gi:4506718 /UG=Hs.182426 ribosomal protein S2 /FL=gb:BC001795.1 gb:NM_002952.1" NM_002952 "ribosomal protein S2 /// small nucleolar RNA, H/ACA box 64" RPS2 /// SNORA64 6187 /// 26784 NM_002952 /// NR_002326 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051347 // positive regulation of transferase activity // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203108_at NM_003979 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003979.2 /DEF=Homo sapiens retinoic acid induced 3 (RAI3), mRNA. /FEA=mRNA /GEN=RAI3 /PROD=retinoic acid induced 3 /DB_XREF=gi:12056470 /UG=Hs.194691 retinoic acid induced 3 /FL=gb:NM_003979.2 gb:BC003665.1 gb:AF095448.1" NM_003979 "G protein-coupled receptor, class C, group 5, member A" GPRC5A 9052 NM_003979 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation 203109_at NM_003969 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003969.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2M (homologous to yeast UBC12) (UBE2M), mRNA. /FEA=mRNA /GEN=UBE2M /PROD=ubiquitin-conjugating enzyme E2M (homologous toyeast UBC12) /DB_XREF=gi:4507790 /UG=Hs.200478 ubiquitin-conjugating enzyme E2M (homologous to yeast UBC12) /FL=gb:AF075599.1 gb:AB012191.1 gb:NM_003969.1" NM_003969 ubiquitin-conjugating enzyme E2M UBE2M 9040 NM_003969 0006464 // cellular protein modification process // inferred from mutant phenotype /// 0006464 // cellular protein modification process // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045116 // protein neddylation // inferred from direct assay /// 0045116 // protein neddylation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0018169 // ribosomal S6-glutamic acid ligase activity // inferred from direct assay /// 0019788 // NEDD8 ligase activity // inferred from direct assay 203110_at U43522 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U43522.1 /DEF=Human cell adhesion kinase beta (CAKbeta) mRNA, complete cds. /FEA=mRNA /GEN=CAKbeta /PROD=cell adhesion kinase beta /DB_XREF=gi:1165218 /UG=Hs.20313 protein tyrosine kinase 2 beta /FL=gb:L49207.1 gb:U43522.1 gb:NM_004103.1 gb:U33284.1" U43522 protein tyrosine kinase 2 beta PTK2B 2185 NM_004103 /// NM_173174 /// NM_173175 /// NM_173176 /// XM_005273447 /// XM_005273448 "0000165 // MAPK cascade // inferred from electronic annotation /// 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0002315 // marginal zone B cell differentiation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006968 // cellular defense response // inferred from sequence or structural similarity /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from mutant phenotype /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0010752 // regulation of cGMP-mediated signaling // inferred from electronic annotation /// 0010758 // regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030502 // negative regulation of bone mineralization // inferred from sequence or structural similarity /// 0030826 // regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from electronic annotation /// 0032960 // regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042976 // activation of Janus kinase activity // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0045428 // regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050848 // regulation of calcium-mediated signaling // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070098 // chemokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 2000058 // regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 2000114 // regulation of establishment of cell polarity // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000538 // positive regulation of B cell chemotaxis // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0097440 // apical dendrite // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043423 // 3-phosphoinositide-dependent protein kinase binding // inferred from electronic annotation" 203111_s_at NM_004103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004103.1 /DEF=Homo sapiens protein tyrosine kinase 2 beta (PTK2B), mRNA. /FEA=mRNA /GEN=PTK2B /PROD=protein tyrosine kinase 2 beta /DB_XREF=gi:4758975 /UG=Hs.20313 protein tyrosine kinase 2 beta /FL=gb:L49207.1 gb:U43522.1 gb:NM_004103.1 gb:U33284.1" NM_004103 protein tyrosine kinase 2 beta PTK2B 2185 NM_004103 /// NM_173174 /// NM_173175 /// NM_173176 /// XM_005273447 /// XM_005273448 "0000165 // MAPK cascade // inferred from electronic annotation /// 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001954 // positive regulation of cell-matrix adhesion // inferred from mutant phenotype /// 0002040 // sprouting angiogenesis // inferred from sequence or structural similarity /// 0002315 // marginal zone B cell differentiation // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006968 // cellular defense response // inferred from sequence or structural similarity /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from mutant phenotype /// 0007172 // signal complex assembly // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0010752 // regulation of cGMP-mediated signaling // inferred from electronic annotation /// 0010758 // regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from mutant phenotype /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030502 // negative regulation of bone mineralization // inferred from sequence or structural similarity /// 0030826 // regulation of cGMP biosynthetic process // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from electronic annotation /// 0032960 // regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from mutant phenotype /// 0035235 // ionotropic glutamate receptor signaling pathway // inferred from sequence or structural similarity /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042976 // activation of Janus kinase activity // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043149 // stress fiber assembly // inferred from electronic annotation /// 0043267 // negative regulation of potassium ion transport // inferred from direct assay /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0045428 // regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045453 // bone resorption // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // traceable author statement /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from mutant phenotype /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050848 // regulation of calcium-mediated signaling // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051968 // positive regulation of synaptic transmission, glutamatergic // inferred from sequence or structural similarity /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070098 // chemokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 2000058 // regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 2000114 // regulation of establishment of cell polarity // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // inferred from sequence or structural similarity /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000538 // positive regulation of B cell chemotaxis // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0097440 // apical dendrite // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004683 // calmodulin-dependent protein kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // non-traceable author statement /// 0004972 // N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043423 // 3-phosphoinositide-dependent protein kinase binding // inferred from electronic annotation" 203112_s_at NM_005663 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005663.1 /DEF=Homo sapiens Wolf-Hirschhorn syndrome candidate 2 (WHSC2), mRNA. /FEA=mRNA /GEN=WHSC2 /PROD=WHSC2 protein /DB_XREF=gi:5032226 /UG=Hs.21771 Wolf-Hirschhorn syndrome candidate 2 /FL=gb:BC002764.1 gb:AF101434.1 gb:NM_005663.1" NM_005663 microRNA 943 /// negative elongation factor complex member A MIR943 /// NELFA 7469 /// 100126332 NM_005663 /// NR_030641 /// XM_006713916 /// XM_006713917 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032021 // NELF complex // inferred from direct assay 0003682 // chromatin binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203113_s_at NM_001960 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001960.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D), mRNA. /FEA=mRNA /GEN=EEF1D /PROD=eukaryotic translation elongation factor 1 delta(guanine nucleotide exchange protein) /DB_XREF=gi:4503478 /UG=Hs.223241 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) /FL=gb:NM_001960.1" NM_001960 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) EEF1D 1936 NM_001130053 /// NM_001130054 /// NM_001130055 /// NM_001130056 /// NM_001130057 /// NM_001195203 /// NM_001289950 /// NM_001960 /// NM_032378 /// XM_005250820 /// XM_005250821 /// XM_005250823 /// XM_005250824 /// XM_005250825 /// XM_005250826 /// XM_006716519 /// XM_006716520 /// XM_006716521 /// XM_006716522 /// XM_006716523 /// XM_006716524 /// XM_006716525 /// XM_006725064 /// XM_006725065 /// XM_006725066 /// XM_006725067 /// XM_006725068 /// XM_006725069 /// XM_006725070 /// XM_006725071 /// XM_006725072 /// XM_006725073 /// XM_006725074 /// XM_006725075 /// XM_006725076 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation "0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement" 203114_at NM_006396 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006396.1 /DEF=Homo sapiens Sjogrens syndromescleroderma autoantigen 1 (SSSCA1), mRNA. /FEA=mRNA /GEN=SSSCA1 /PROD=Sjogrens syndromescleroderma autoantigen 1 /DB_XREF=gi:5453837 /UG=Hs.25723 Sjogrens syndromescleroderma autoantigen 1 /FL=gb:AB001740.1 gb:NM_006396.1" NM_006396 Sjogren syndrome/scleroderma autoantigen 1 SSSCA1 10534 NM_006396 0002084 // protein depalmitoylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0042997 // negative regulation of Golgi to plasma membrane protein transport // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203115_at AU152635 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU152635 /FEA=EST /DB_XREF=gi:11014156 /DB_XREF=est:AU152635 /CLONE=NT2RP3001344 /UG=Hs.26 ferrochelatase (protoporphyria) /FL=gb:NM_000140.1 AU152635 ferrochelatase FECH 2235 NM_000140 /// NM_001012515 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009416 // response to light stimulus // traceable author statement /// 0009589 // detection of UV // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046501 // protoporphyrinogen IX metabolic process // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0070541 // response to platinum ion // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0004325 // ferrochelatase activity // inferred from direct assay /// 0004325 // ferrochelatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008198 // ferrous iron binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030350 // iron-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046906 // tetrapyrrole binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation" 203116_s_at NM_000140 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000140.1 /DEF=Homo sapiens ferrochelatase (protoporphyria) (FECH), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FECH /PROD=ferrochelatase precursor /DB_XREF=gi:4557592 /UG=Hs.26 ferrochelatase (protoporphyria) /FL=gb:NM_000140.1" NM_000140 ferrochelatase FECH 2235 NM_000140 /// NM_001012515 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009416 // response to light stimulus // traceable author statement /// 0009589 // detection of UV // inferred from electronic annotation /// 0010038 // response to metal ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010999 // regulation of eIF2 alpha phosphorylation by heme // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0034379 // very-low-density lipoprotein particle assembly // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046501 // protoporphyrinogen IX metabolic process // inferred from direct assay /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046984 // regulation of hemoglobin biosynthetic process // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0070541 // response to platinum ion // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0004325 // ferrochelatase activity // inferred from direct assay /// 0004325 // ferrochelatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008198 // ferrous iron binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030350 // iron-responsive element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046906 // tetrapyrrole binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation" 203117_s_at NM_014871 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014871.1 /DEF=Homo sapiens KIAA0710 gene product (KIAA0710), mRNA. /FEA=mRNA /GEN=KIAA0710 /PROD=KIAA0710 gene product /DB_XREF=gi:7662257 /UG=Hs.273397 KIAA0710 gene product /FL=gb:AB014610.1 gb:NM_014871.1" NM_014871 PAN2 poly(A) specific ribonuclease subunit PAN2 9924 NM_001127460 /// NM_001166279 /// NM_014871 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from direct assay /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement" 0000932 // cytoplasmic mRNA processing body // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0031251 // PAN complex // inferred from direct assay 0000175 // 3'-5'-exoribonuclease activity // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // inferred from direct assay /// 0004535 // poly(A)-specific ribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203118_at NM_004716 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004716.1 /DEF=Homo sapiens proprotein convertase subtilisinkexin type 7 (PCSK7), mRNA. /FEA=mRNA /GEN=PCSK7 /PROD=proprotein convertase subtilisinkexin type 7 /DB_XREF=gi:4758887 /UG=Hs.32978 proprotein convertase subtilisinkexin type 7 /FL=gb:U40623.1 gb:U33849.1 gb:NM_004716.1" NM_004716 proprotein convertase subtilisin/kexin type 7 PCSK7 9159 NM_004716 /// XM_006718938 /// XM_006718939 /// XM_006718940 /// XR_428984 /// XR_428985 0006508 // proteolysis // inferred from electronic annotation /// 0016485 // protein processing // inferred from direct assay /// 0016486 // peptide hormone processing // non-traceable author statement 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay 0004252 // serine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from direct assay /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203119_at NM_024098 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024098.1 /DEF=Homo sapiens hypothetical protein MGC2574 (MGC2574), mRNA. /FEA=mRNA /GEN=MGC2574 /PROD=hypothetical protein MGC2574 /DB_XREF=gi:13129103 /UG=Hs.4253 hypothetical protein MGC2574 /FL=gb:BC001378.1 gb:NM_024098.1" NM_024098 coiled-coil domain containing 86 CCDC86 79080 NM_024098 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203120_at NM_005426 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005426.1 /DEF=Homo sapiens tumor protein p53-binding protein, 2 (TP53BP2), mRNA. /FEA=mRNA /GEN=TP53BP2 /PROD=tumor protein p53-binding protein, 2 /DB_XREF=gi:4885642 /UG=Hs.44585 tumor protein p53-binding protein, 2 /FL=gb:U58334.1 gb:NM_005426.1" NM_005426 tumor protein p53 binding protein 2 TP53BP2 7159 NM_001031685 /// NM_005426 /// XM_005273246 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009792 // embryo development ending in birth or egg hatching // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 203122_at NM_016030 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016030.1 /DEF=Homo sapiens CGI-87 protein (LOC51112), mRNA. /FEA=mRNA /GEN=LOC51112 /PROD=CGI-87 protein /DB_XREF=gi:7705796 /UG=Hs.5008 CGI-87 protein /FL=gb:AF151845.1 gb:NM_016030.1" NM_016030 trafficking protein particle complex 12 TRAPPC12 51112 NM_016030 /// XM_005264693 /// XM_006711887 /// XR_426956 "0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation" 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203123_s_at AU154469 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU154469 /FEA=EST /DB_XREF=gi:11015990 /DB_XREF=est:AU154469 /CLONE=NT2RP4001182 /UG=Hs.57435 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 /FL=gb:NM_000617.1 gb:BC002592.1 gb:AB004857.1 gb:AF046997.1" AU154469 "solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2" SLC11A2 4891 NM_000617 /// NM_001174125 /// NM_001174126 /// NM_001174127 /// NM_001174128 /// NM_001174129 /// NM_001174130 /// NR_033421 /// NR_033422 /// XM_005268911 /// XM_005268912 /// XM_005268913 /// XM_005268914 /// XM_005268916 /// XR_429104 0000041 // transition metal ion transport // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0003032 // detection of oxygen // inferred from expression pattern /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from direct assay /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from expression pattern /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0015675 // nickel cation transport // inferred from direct assay /// 0015676 // vanadium ion transport // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from direct assay /// 0015692 // lead ion transport // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0035444 // nickel cation transmembrane transport // inferred from direct assay /// 0035444 // nickel cation transmembrane transport // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from mutant phenotype /// 0070574 // cadmium ion transmembrane transport // inferred from direct assay /// 0070627 // ferrous iron import // inferred from direct assay /// 0070627 // ferrous iron import // inferred from electronic annotation /// 0071281 // cellular response to iron ion // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071421 // manganese ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005773 // vacuole // inferred from mutant phenotype /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070826 // paraferritin complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005375 // copper ion transmembrane transporter activity // inferred from direct assay /// 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from direct assay /// 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015086 // cadmium ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from direct assay /// 0015094 // lead ion transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from electronic annotation /// 0015100 // vanadium ion transmembrane transporter activity // inferred from direct assay /// 0015295 // solute:proton symporter activity // inferred from direct assay /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // inferred from genetic interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation /// 0070835 // chromium ion transmembrane transporter activity // inferred from direct assay 203124_s_at NM_000617 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000617.1 /DEF=Homo sapiens solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2), mRNA. /FEA=mRNA /GEN=SLC11A2 /PROD=solute carrier family 11 (proton-coupleddivalent metal ion transporters), member 2 /DB_XREF=gi:10835168 /UG=Hs.57435 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 /FL=gb:NM_000617.1 gb:BC002592.1 gb:AB004857.1 gb:AF046997.1" NM_000617 "solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2" SLC11A2 4891 NM_000617 /// NM_001174125 /// NM_001174126 /// NM_001174127 /// NM_001174128 /// NM_001174129 /// NM_001174130 /// NR_033421 /// NR_033422 /// XM_005268911 /// XM_005268912 /// XM_005268913 /// XM_005268914 /// XM_005268916 /// XR_429104 0000041 // transition metal ion transport // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0003032 // detection of oxygen // inferred from expression pattern /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from direct assay /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from expression pattern /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0015675 // nickel cation transport // inferred from direct assay /// 0015676 // vanadium ion transport // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from direct assay /// 0015692 // lead ion transport // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0035444 // nickel cation transmembrane transport // inferred from direct assay /// 0035444 // nickel cation transmembrane transport // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from mutant phenotype /// 0070574 // cadmium ion transmembrane transport // inferred from direct assay /// 0070627 // ferrous iron import // inferred from direct assay /// 0070627 // ferrous iron import // inferred from electronic annotation /// 0071281 // cellular response to iron ion // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071421 // manganese ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005773 // vacuole // inferred from mutant phenotype /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070826 // paraferritin complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005375 // copper ion transmembrane transporter activity // inferred from direct assay /// 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from direct assay /// 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015086 // cadmium ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from direct assay /// 0015094 // lead ion transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from electronic annotation /// 0015100 // vanadium ion transmembrane transporter activity // inferred from direct assay /// 0015295 // solute:proton symporter activity // inferred from direct assay /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // inferred from genetic interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation /// 0070835 // chromium ion transmembrane transporter activity // inferred from direct assay 203125_x_at AF046997 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF046997.1 /DEF=Homo sapiens NRAMP2 iron transporter mRNA, complete cds. /FEA=mRNA /PROD=NRAMP2 iron transporter /DB_XREF=gi:3170363 /UG=Hs.57435 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 /FL=gb:NM_000617.1 gb:BC002592.1 gb:AB004857.1 gb:AF046997.1" AF046997 "solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2" SLC11A2 4891 NM_000617 /// NM_001174125 /// NM_001174126 /// NM_001174127 /// NM_001174128 /// NM_001174129 /// NM_001174130 /// NR_033421 /// NR_033422 /// XM_005268911 /// XM_005268912 /// XM_005268913 /// XM_005268914 /// XM_005268916 /// XR_429104 0000041 // transition metal ion transport // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from expression pattern /// 0003032 // detection of oxygen // inferred from expression pattern /// 0006778 // porphyrin-containing compound metabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from direct assay /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from direct assay /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006828 // manganese ion transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from expression pattern /// 0010042 // response to manganese ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0015675 // nickel cation transport // inferred from direct assay /// 0015676 // vanadium ion transport // inferred from direct assay /// 0015684 // ferrous iron transport // inferred from direct assay /// 0015692 // lead ion transport // inferred from direct assay /// 0015992 // proton transport // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0034755 // iron ion transmembrane transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0035444 // nickel cation transmembrane transport // inferred from direct assay /// 0035444 // nickel cation transmembrane transport // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060586 // multicellular organismal iron ion homeostasis // inferred from mutant phenotype /// 0070574 // cadmium ion transmembrane transport // inferred from direct assay /// 0070627 // ferrous iron import // inferred from direct assay /// 0070627 // ferrous iron import // inferred from electronic annotation /// 0071281 // cellular response to iron ion // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071421 // manganese ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071577 // zinc ion transmembrane transport // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005773 // vacuole // inferred from mutant phenotype /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from mutant phenotype /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070826 // paraferritin complex // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005375 // copper ion transmembrane transporter activity // inferred from direct assay /// 0005381 // iron ion transmembrane transporter activity // inferred from electronic annotation /// 0005384 // manganese ion transmembrane transporter activity // inferred from direct assay /// 0005385 // zinc ion transmembrane transporter activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015086 // cadmium ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from direct assay /// 0015087 // cobalt ion transmembrane transporter activity // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from direct assay /// 0015094 // lead ion transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from direct assay /// 0015099 // nickel cation transmembrane transporter activity // inferred from electronic annotation /// 0015100 // vanadium ion transmembrane transporter activity // inferred from direct assay /// 0015295 // solute:proton symporter activity // inferred from direct assay /// 0016151 // nickel cation binding // inferred from electronic annotation /// 0022890 // inorganic cation transmembrane transporter activity // inferred from genetic interaction /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046870 // cadmium ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation /// 0070835 // chromium ion transmembrane transporter activity // inferred from direct assay 203126_at NM_014214 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014214.1 /DEF=Homo sapiens inositol(myo)-1(or 4)-monophosphatase 2 (IMPA2), mRNA. /FEA=mRNA /GEN=IMPA2 /PROD=inositol(myo)-1(or 4)-monophosphatase 2 /DB_XREF=gi:7657235 /UG=Hs.5753 inositol(myo)-1(or 4)-monophosphatase 2 /FL=gb:AF200432.1 gb:NM_014214.1 gb:AF014398.2" NM_014214 inositol(myo)-1(or 4)-monophosphatase 2 IMPA2 3613 NM_014214 0006021 // inositol biosynthetic process // inferred from electronic annotation /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0008934 // inositol monophosphate 1-phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052832 // inositol monophosphate 3-phosphatase activity // inferred from electronic annotation /// 0052833 // inositol monophosphate 4-phosphatase activity // inferred from electronic annotation /// 0052834 // inositol monophosphate phosphatase activity // inferred from electronic annotation 203127_s_at BC005123 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005123.1 /DEF=Homo sapiens, serine palmitoyltransferase, long chain base subunit 2, clone MGC:10362, mRNA, complete cds. /FEA=mRNA /PROD=serine palmitoyltransferase, long chain basesubunit 2 /DB_XREF=gi:13477298 /UG=Hs.59403 serine palmitoyltransferase, long chain base subunit 2 /FL=gb:BC005123.1 gb:AB011098.1 gb:NM_004863.1" BC005123 "serine palmitoyltransferase, long chain base subunit 2" SPTLC2 9517 NM_004863 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation" 203128_at NM_004863 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004863.1 /DEF=Homo sapiens serine palmitoyltransferase, long chain base subunit 2 (SPTLC2), mRNA. /FEA=mRNA /GEN=SPTLC2 /PROD=serine palmitoyltransferase, long chain basesubunit 2 /DB_XREF=gi:4758667 /UG=Hs.59403 serine palmitoyltransferase, long chain base subunit 2 /FL=gb:BC005123.1 gb:AB011098.1 gb:NM_004863.1" NM_004863 "serine palmitoyltransferase, long chain base subunit 2" SPTLC2 9517 NM_004863 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006686 // sphingomyelin biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046511 // sphinganine biosynthetic process // inferred from electronic annotation /// 0046512 // sphingosine biosynthetic process // inferred from electronic annotation /// 0046513 // ceramide biosynthetic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0017059 // serine C-palmitoyltransferase complex // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation" 203129_s_at BF059313 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF059313 /FEA=EST /DB_XREF=gi:10813297 /DB_XREF=est:7k60c04.x1 /CLONE=IMAGE:3479791 /UG=Hs.6641 kinesin family member 5C /FL=gb:AB011103.1 gb:NM_004522.1 BF059313 kinesin family member 5C KIF5C 3800 NM_004522 /// NR_111932 0006810 // transport // inferred from electronic annotation /// 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203130_s_at NM_004522 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004522.1 /DEF=Homo sapiens kinesin family member 5C (KIF5C), mRNA. /FEA=mRNA /GEN=KIF5C /PROD=kinesin family member 5C /DB_XREF=gi:4758649 /UG=Hs.6641 kinesin family member 5C /FL=gb:AB011103.1 gb:NM_004522.1" NM_004522 kinesin family member 5C KIF5C 3800 NM_004522 /// NR_111932 0006810 // transport // inferred from electronic annotation /// 0006996 // organelle organization // traceable author statement /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203131_at NM_006206 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006206.1 /DEF=Homo sapiens platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), mRNA. /FEA=mRNA /GEN=PDGFRA /PROD=platelet-derived growth factor receptor, alphapolypeptide /DB_XREF=gi:5453869 /UG=Hs.74615 platelet-derived growth factor receptor, alpha polypeptide /FL=gb:M21574.1 gb:NM_006206.1" NM_006206 "platelet-derived growth factor receptor, alpha polypeptide" PDGFRA 5156 NM_006206 /// XM_005265743 /// XM_006714039 /// XM_006714040 /// XM_006714041 0001553 // luteinization // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001775 // cell activation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008585 // female gonad development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010863 // positive regulation of phospholipase C activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023019 // signal transduction involved in regulation of gene expression // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030539 // male genitalia development // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0035790 // platelet-derived growth factor receptor-alpha signaling pathway // inferred from mutant phenotype /// 0038091 // positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048704 // embryonic skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050920 // regulation of chemotaxis // inferred from mutant phenotype /// 0055003 // cardiac myofibril assembly // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0061298 // retina vasculature development in camera-type eye // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070527 // platelet aggregation // inferred from mutant phenotype /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0072277 // metanephric glomerular capillary formation // inferred from sequence or structural similarity /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2000739 // regulation of mesenchymal stem cell differentiation // inferred from mutant phenotype 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from direct assay /// 0005018 // platelet-derived growth factor alpha-receptor activity // inferred from mutant phenotype /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from direct assay /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction" 203132_at NM_000321 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000321.1 /DEF=Homo sapiens retinoblastoma 1 (including osteosarcoma) (RB1), mRNA. /FEA=mRNA /GEN=RB1 /PROD=retinoblastoma 1 (including osteosarcoma) /DB_XREF=gi:4506434 /UG=Hs.75770 retinoblastoma 1 (including osteosarcoma) /FL=gb:M33647.1 gb:M15400.1 gb:M28419.1 gb:NM_000321.1" NM_000321 retinoblastoma 1 RB1 5925 NM_000321 "0000075 // cell cycle checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from physical interaction /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007070 // negative regulation of transcription from RNA polymerase II promoter during mitosis // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007346 // regulation of mitotic cell cycle // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031134 // sister chromatid biorientation // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034088 // maintenance of mitotic sister chromatid cohesion // inferred from mutant phenotype /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0042551 // neuron maturation // inferred from electronic annotation /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043550 // regulation of lipid kinase activity // inferred from direct assay /// 0045445 // myoblast differentiation // inferred from mutant phenotype /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071459 // protein localization to chromosome, centromeric region // inferred from mutant phenotype /// 0071922 // regulation of cohesin localization to chromatin // inferred from mutant phenotype /// 0071930 // negative regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0090230 // regulation of centromere complex assembly // traceable author statement /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // traceable author statement" 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0016514 // SWI/SNF complex // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0035189 // Rb-E2F complex // traceable author statement 0001047 // core promoter binding // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation /// 0019900 // kinase binding // inferred from direct assay /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement /// 0051219 // phosphoprotein binding // inferred from physical interaction 203133_at NM_006808 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006808.1 /DEF=Homo sapiens protein translocation complex beta (SEC61B), mRNA. /FEA=mRNA /GEN=SEC61B /PROD=protein translocation complex beta /DB_XREF=gi:5803164 /UG=Hs.77028 protein translocation complex beta /FL=gb:BC001734.1 gb:L25085.1 gb:NM_006808.1" NM_006808 Sec61 beta subunit SEC61B 10952 NM_006808 "0000060 // protein import into nucleus, translocation // inferred from mutant phenotype /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from mutant phenotype /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement" 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0031205 // endoplasmic reticulum Sec complex // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0048408 // epidermal growth factor binding // inferred from physical interaction 203134_at NM_007166 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007166.1 /DEF=Homo sapiens Clathrin assembly lymphoid-myeloid leukemia gene (CLTH), mRNA. /FEA=mRNA /GEN=CLTH /PROD=Clathrin assembly lymphoid-myeloid leukemiagene /DB_XREF=gi:6005732 /UG=Hs.7885 phosphatidylinositol binding clathrin assembly protein /FL=gb:U45976.1 gb:NM_007166.1" NM_007166 phosphatidylinositol binding clathrin assembly protein PICALM 8301 NM_001008660 /// NM_001206946 /// NM_001206947 /// NM_007166 /// XM_005274322 /// XM_005274323 /// XM_005274324 /// XM_005274325 /// XM_005274326 /// XM_005274327 /// XM_005274328 /// XM_005274329 /// XM_005274330 /// XM_005274331 /// XM_005274332 /// XM_005274333 /// XM_005274334 /// XM_005274335 /// XM_005274336 /// XM_005274337 /// XM_005274338 /// XM_005274340 /// XM_006718699 /// XM_006718700 /// XM_006718701 /// XM_006718702 "0006461 // protein complex assembly // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016188 // synaptic vesicle maturation // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from mutant phenotype /// 0031623 // receptor internalization // inferred from mutant phenotype /// 0032880 // regulation of protein localization // inferred from direct assay /// 0035459 // cargo loading into vesicle // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0048268 // clathrin coat assembly // inferred from mutant phenotype /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0072583 // clathrin-mediated endocytosis // inferred from mutant phenotype /// 0097459 // iron ion import into cell // inferred from mutant phenotype /// 1901216 // positive regulation of neuron death // inferred from mutant phenotype /// 1902004 // positive regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902959 // regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902961 // positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from sequence or structural similarity" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // inferred from electronic annotation /// 0030122 // AP-2 adaptor complex // inferred from direct assay /// 0030132 // clathrin coat of coated pit // inferred from direct assay /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0097418 // neurofibrillary tangle // inferred from mutant phenotype 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // inferred from sequence or structural similarity /// 0030276 // clathrin binding // inferred from direct assay /// 0030276 // clathrin binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from sequence or structural similarity /// 0032050 // clathrin heavy chain binding // inferred from direct assay /// 0035615 // clathrin adaptor activity // inferred from mutant phenotype 203135_at NM_003194 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003194.1 /DEF=Homo sapiens TATA box binding protein (TBP), mRNA. /FEA=mRNA /GEN=TBP /PROD=TATA box binding protein /DB_XREF=gi:4507378 /UG=Hs.1100 TATA box binding protein /FL=gb:M34960.1 gb:M55654.1 gb:NM_003194.1" NM_003194 TATA box binding protein TBP 6908 NM_001172085 /// NM_003194 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred by curator /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005672 // transcription factor TFIIA complex // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0045120 // pronucleus // inferred from electronic annotation 0001103 // RNA polymerase II repressing transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from physical interaction 203136_at NM_006423 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006423.1 /DEF=Homo sapiens Rab acceptor 1 (prenylated) (RABAC1), mRNA. /FEA=mRNA /GEN=RABAC1 /PROD=Rab acceptor 1 (prenylated) /DB_XREF=gi:5453959 /UG=Hs.11417 Rab acceptor 1 (prenylated) /FL=gb:NM_006423.1 gb:AF112202.1" NM_006423 Rab acceptor 1 (prenylated) RABAC1 10567 NM_006423 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from electronic annotation 203137_at NM_004906 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004906.1 /DEF=Homo sapiens Wilms tumour 1-associating protein (KIAA0105), mRNA. /FEA=mRNA /GEN=KIAA0105 /PROD=Wilms tumour 1-associating protein /DB_XREF=gi:4758635 /UG=Hs.119 Wilms tumour 1-associating protein /FL=gb:AF277190.1 gb:D14661.1 gb:NM_004906.1" NM_004906 Wilms tumor 1 associated protein WTAP 9589 NM_001270531 /// NM_001270532 /// NM_001270533 /// NM_004906 /// NM_152857 /// NM_152858 "0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0080009 // mRNA methylation // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0036396 // MIS complex // inferred from direct assay 203138_at NM_003642 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003642.1 /DEF=Homo sapiens histone acetyltransferase 1 (HAT1), mRNA. /FEA=mRNA /GEN=HAT1 /PROD=histone acetyltransferase 1 /DB_XREF=gi:4504340 /UG=Hs.13340 histone acetyltransferase 1 /FL=gb:AF030424.1 gb:NM_003642.1" NM_003642 histone acetyltransferase 1 HAT1 8520 NM_001033085 /// NM_003642 /// NR_027862 /// XM_006712808 0006323 // DNA packaging // traceable author statement /// 0006325 // chromatin organization // traceable author statement /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006348 // chromatin silencing at telomere // inferred from electronic annotation /// 0006475 // internal protein amino acid acetylation // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay "0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation" 203139_at NM_004938 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004938.1 /DEF=Homo sapiens death-associated protein kinase 1 (DAPK1), mRNA. /FEA=mRNA /GEN=DAPK1 /PROD=death-associated protein kinase 1 /DB_XREF=gi:4826683 /UG=Hs.153924 death-associated protein kinase 1 /FL=gb:NM_004938.1" NM_004938 death-associated protein kinase 1 DAPK1 1612 NM_001288729 /// NM_001288730 /// NM_001288731 /// NM_004938 /// XM_005251757 /// XM_006716988 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from genetic interaction /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction" 203140_at NM_001706 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001706.1 /DEF=Homo sapiens B-cell CLLlymphoma 6 (zinc finger protein 51) (BCL6), mRNA. /FEA=mRNA /GEN=BCL6 /PROD=B-cell CLLlymphoma 6 (zinc finger protein 51) /DB_XREF=gi:4502382 /UG=Hs.155024 B-cell CLLlymphoma 6 (zinc finger protein 51) /FL=gb:U00115.1 gb:NM_001706.1" NM_001706 B-cell CLL/lymphoma 6 BCL6 604 NM_001130845 /// NM_001134738 /// NM_001706 /// NM_138931 /// XM_005247694 "0000060 // protein import into nucleus, translocation // inferred from genetic interaction /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002467 // germinal center formation // inferred from electronic annotation /// 0002634 // regulation of germinal center formation // non-traceable author statement /// 0002829 // negative regulation of type 2 immune response // inferred from electronic annotation /// 0002903 // negative regulation of B cell apoptotic process // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032764 // negative regulation of mast cell cytokine production // inferred from electronic annotation /// 0035024 // negative regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042092 // type 2 immune response // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043380 // regulation of memory T cell differentiation // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045629 // negative regulation of T-helper 2 cell differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement /// 0048294 // negative regulation of isotype switching to IgE isotypes // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050776 // regulation of immune response // non-traceable author statement /// 0051272 // positive regulation of cellular component movement // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005657 // replication fork // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203141_s_at AW058575 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW058575 /FEA=EST /DB_XREF=gi:5934214 /DB_XREF=est:wx23f04.x1 /CLONE=IMAGE:2544511 /UG=Hs.155172 adaptor-related protein complex 3, beta 1 subunit /FL=gb:U91931.1 gb:U81504.1 gb:NM_003664.1" AW058575 "adaptor-related protein complex 3, beta 1 subunit" AP3B1 8546 NM_001271769 /// NM_003664 /// XM_005248618 /// XM_005248619 "0006622 // protein targeting to lysosome // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation" 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 203142_s_at NM_003664 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003664.1 /DEF=Homo sapiens adaptor-related protein complex 3, beta 1 subunit (AP3B1), mRNA. /FEA=mRNA /GEN=AP3B1 /PROD=adaptor-related protein complex 3, beta 1subunit /DB_XREF=gi:4501974 /UG=Hs.155172 adaptor-related protein complex 3, beta 1 subunit /FL=gb:U91931.1 gb:U81504.1 gb:NM_003664.1" NM_003664 "adaptor-related protein complex 3, beta 1 subunit" AP3B1 8546 NM_001271769 /// NM_003664 /// XM_005248618 /// XM_005248619 "0006622 // protein targeting to lysosome // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0048007 // antigen processing and presentation, exogenous lipid antigen via MHC class Ib // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity /// 0051138 // positive regulation of NK T cell differentiation // inferred from electronic annotation" 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030123 // AP-3 adaptor complex // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 203143_s_at T79953 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:T79953 /FEA=EST /DB_XREF=gi:698462 /DB_XREF=est:yd85c11.s1 /CLONE=IMAGE:115028 /UG=Hs.158282 KIAA0040 gene product /FL=gb:D25539.1 gb:NM_014656.1 T79953 KIAA0040 KIAA0040 9674 NM_001162893 /// NM_001162894 /// NM_001162895 /// NM_014656 /// XM_005245628 203144_s_at NM_014656 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014656.1 /DEF=Homo sapiens KIAA0040 gene product (KIAA0040), mRNA. /FEA=mRNA /GEN=KIAA0040 /PROD=KIAA0040 gene product /DB_XREF=gi:7657258 /UG=Hs.158282 KIAA0040 gene product /FL=gb:D25539.1 gb:NM_014656.1" NM_014656 KIAA0040 KIAA0040 9674 NM_001162893 /// NM_001162894 /// NM_001162895 /// NM_014656 /// XM_005245628 203145_at NM_006461 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006461.1 /DEF=Homo sapiens mitotic spindle coiled-coil related protein (DEEPEST), mRNA. /FEA=mRNA /GEN=DEEPEST /PROD=mitotic spindle coiled-coil related protein /DB_XREF=gi:5453631 /UG=Hs.16244 mitotic spindle coiled-coil related protein /FL=gb:BC000322.1 gb:AF063308.1 gb:NM_006461.1" NM_006461 sperm associated antigen 5 SPAG5 10615 NM_006461 0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007051 // spindle organization // non-traceable author statement /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay" "0005515 // protein binding // inferred from physical interaction /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203146_s_at NM_001470 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001470.1 /DEF=Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 1, mRNA. /FEA=mRNA /GEN=GABBR1 /PROD=gamma-aminobutyric acid (GABA) B receptor 1,isoform a precursor /DB_XREF=gi:10835014 /UG=Hs.167017 gamma-aminobutyric acid (GABA) B receptor, 1 /FL=gb:NM_001470.1 gb:AF301005.1 gb:AF099148.1" NM_001470 "gamma-aminobutyric acid (GABA) B receptor, 1" GABBR1 2550 NM_001470 /// NM_021903 /// NM_021904 /// NM_021905 /// XM_005248982 /// XM_005272785 /// XM_005274841 /// XM_005274931 /// XM_005275088 /// XM_005275227 /// XM_005275363 /// XM_006715047 /// XM_006725030 /// XM_006725477 /// XM_006725691 /// XM_006725807 /// XM_006725901 /// XM_006725988 /// XR_241884 /// XR_246960 /// XR_247352 /// XR_247386 /// XR_247400 /// XR_430672 /// XR_430972 0006508 // proteolysis // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032446 // protein modification by small protein conjugation // non-traceable author statement /// 0034341 // response to interferon-gamma // inferred from electronic annotation /// 0034341 // response to interferon-gamma // inferred from expression pattern /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0043011 // myeloid dendritic cell differentiation // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0070842 // aggresome assembly // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016235 // aggresome // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0038037 // G-protein coupled receptor dimeric complex // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070628 // proteasome binding // inferred from direct assay 203147_s_at BE962483 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE962483 /FEA=EST /DB_XREF=gi:11765431 /DB_XREF=est:601655782R1 /CLONE=IMAGE:3846116 /UG=Hs.179703 KIAA0129 gene product /FL=gb:D50919.1 gb:NM_014788.1 BE962483 tripartite motif containing 14 TRIM14 9830 NM_014788 /// NM_033219 /// NM_033220 /// NM_033221 /// XM_005252320 /// XM_005252321 /// XM_005252322 /// XM_005252323 /// XM_006717338 /// XM_006717339 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203148_s_at NM_014788 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014788.1 /DEF=Homo sapiens KIAA0129 gene product (KIAA0129), mRNA. /FEA=mRNA /GEN=KIAA0129 /PROD=KIAA0129 gene product /DB_XREF=gi:7661927 /UG=Hs.179703 KIAA0129 gene product /FL=gb:D50919.1 gb:NM_014788.1" NM_014788 tripartite motif containing 14 TRIM14 9830 NM_014788 /// NM_033219 /// NM_033220 /// NM_033221 /// XM_005252320 /// XM_005252321 /// XM_005252322 /// XM_005252323 /// XM_006717338 /// XM_006717339 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203149_at NM_002856 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002856.1 /DEF=Homo sapiens poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), mRNA. /FEA=mRNA /GEN=PVRL2 /PROD=poliovirus receptor-related 2 (herpesvirus entrymediator B) /DB_XREF=gi:5360209 /UG=Hs.183986 poliovirus receptor-related 2 (herpesvirus entry mediator B) /FL=gb:BC003091.1 gb:AF058448.1 gb:NM_002856.1" NM_002856 poliovirus receptor-related 2 (herpesvirus entry mediator B) PVRL2 5819 NM_001042724 /// NM_002856 0001675 // acrosome assembly // inferred from electronic annotation /// 0002860 // positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target // inferred from mutant phenotype /// 0002891 // positive regulation of immunoglobulin mediated immune response // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007289 // spermatid nucleus differentiation // inferred from electronic annotation /// 0009566 // fertilization // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019064 // fusion of virus membrane with host plasma membrane // inferred from direct assay /// 0030382 // sperm mitochondrion organization // inferred from electronic annotation /// 0032990 // cell part morphogenesis // inferred from electronic annotation /// 0033005 // positive regulation of mast cell activation // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042271 // susceptibility to natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0044406 // adhesion of symbiont to host // inferred from direct assay /// 0044782 // cilium organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0046814 // coreceptor-mediated virion attachment to host cell // inferred from direct assay /// 0050776 // regulation of immune response // traceable author statement /// 0051654 // establishment of mitochondrion localization // inferred from electronic annotation /// 0060370 // susceptibility to T cell mediated cytotoxicity // inferred from direct assay 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005915 // zonula adherens // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 203150_at NM_005833 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005833.1 /DEF=Homo sapiens Rab9 effector p40 (RAB9P40), mRNA. /FEA=mRNA /GEN=RAB9P40 /PROD=Rab9 effector p40 /DB_XREF=gi:5032014 /UG=Hs.19012 Rab9 effector p40 /FL=gb:BC000503.1 gb:Z97074.1 gb:NM_005833.1" NM_005833 Rab9 effector protein with kelch motifs RABEPK 10244 NM_001174152 /// NM_001174153 /// NM_005833 /// XM_005251640 /// XM_005251641 /// XM_005251642 /// XM_005251643 /// XM_005251644 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203151_at AW296788 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW296788 /FEA=EST /DB_XREF=gi:6703424 /DB_XREF=est:UI-H-BW0-ajb-d-08-0-UI.s1 /CLONE=IMAGE:2731071 /UG=Hs.194301 microtubule-associated protein 1A /FL=gb:U38292.1 gb:NM_002373.1 gb:U14577.1 AW296788 microtubule-associated protein 1A MAP1A 4130 NM_002373 /// XM_005254385 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203152_at NM_003776 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003776.1 /DEF=Homo sapiens nuclear localization signal deleted in velocardiofacial syndrome (NLVCF), mRNA. /FEA=mRNA /GEN=NLVCF /PROD=nuclear localization signal deleted invelocardiofacial syndrome protein /DB_XREF=gi:4505402 /UG=Hs.19500 nuclear localization signal deleted in velocardiofacial syndrome /FL=gb:AF034091.1 gb:NM_003776.1" NM_003776 mitochondrial ribosomal protein L40 MRPL40 64976 NM_003776 /// XM_005261267 0009653 // anatomical structure morphogenesis // traceable author statement 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // inferred from sequence or structural similarity /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0044822 // poly(A) RNA binding // inferred from direct assay 203153_at NM_001548 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001548.1 /DEF=Homo sapiens interferon-induced protein with tetratricopeptide repeats 1 (IFIT1), mRNA. /FEA=mRNA /GEN=IFIT1 /PROD=interferon-induced protein withtetratricopeptide repeats 1 /DB_XREF=gi:4504584 /UG=Hs.20315 interferon-induced protein with tetratricopeptide repeats 1 /FL=gb:M24594.1 gb:NM_001548.1" NM_001548 interferon-induced protein with tetratricopeptide repeats 1 IFIT1 3434 NM_001270927 /// NM_001270928 /// NM_001270929 /// NM_001270930 /// NM_001548 0002376 // immune system process // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019060 // intracellular transport of viral protein in host cell // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0050689 // negative regulation of defense response to virus by host // inferred from direct assay /// 0051097 // negative regulation of helicase activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0071357 // cellular response to type I interferon // inferred from direct assay /// 0071360 // cellular response to exogenous dsRNA // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203154_s_at NM_005884 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005884.2 /DEF=Homo sapiens protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs (PAK4), mRNA. /FEA=mRNA /GEN=PAK4 /PROD=protein kinase related to S. cerevisiae STE20,effector for Cdc42Hs /DB_XREF=gi:7382497 /UG=Hs.20447 protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs /FL=gb:AF005046.1 gb:NM_005884.2" NM_005884 p21 protein (Cdc42/Rac)-activated kinase 4 PAK4 10298 NM_001014831 /// NM_001014832 /// NM_001014833 /// NM_001014834 /// NM_001014835 /// NM_005884 /// XM_006722971 /// XM_006722972 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016049 // cell growth // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0023014 // signal transduction by phosphorylation // not recorded 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203155_at NM_012432 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012432.1 /DEF=Homo sapiens SET domain, bifurcated 1 (SETDB1), mRNA. /FEA=mRNA /GEN=SETDB1 /PROD=SET domain, bifurcated 1 /DB_XREF=gi:6912651 /UG=Hs.20991 SET domain, bifurcated 1 /FL=gb:D31891.1 gb:NM_012432.1" NM_012432 "SET domain, bifurcated 1" SETDB1 9869 NM_001145415 /// NM_001243491 /// NM_012432 /// XM_005245641 /// XM_006711672 "0001833 // inner cell mass cell proliferation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203156_at NM_016248 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016248.1 /DEF=Homo sapiens A-kinase anchoring protein 220 (LOC51707), mRNA. /FEA=mRNA /GEN=LOC51707 /PROD=A-kinase anchoring protein 220 /DB_XREF=gi:7706456 /UG=Hs.232076 A kinase (PRKA) anchor protein 11 /FL=gb:AF176555.1 gb:NM_016248.1" NM_016248 A kinase (PRKA) anchor protein 11 AKAP11 11215 NM_016248 /// NM_144490 /// XM_005266247 /// XM_005266248 /// XM_005266249 /// XM_005266250 0035556 // intracellular signal transduction // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay 0008157 // protein phosphatase 1 binding // traceable author statement /// 0051018 // protein kinase A binding // traceable author statement 203157_s_at AB020645 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB020645.1 /DEF=Homo sapiens mRNA for KIAA0838 protein, complete cds. /FEA=mRNA /GEN=KIAA0838 /PROD=KIAA0838 protein /DB_XREF=gi:4240164 /UG=Hs.239189 glutaminase /FL=gb:AF327434.1 gb:AB020645.1 gb:AF097493.1 gb:AF223943.1 gb:NM_014905.1" AB020645 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203158_s_at AF097493 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF097493.1 /DEF=Homo sapiens glutaminase kidney isoform mRNA, complete cds. /FEA=mRNA /PROD=glutaminase kidney isoform /DB_XREF=gi:6002672 /UG=Hs.239189 glutaminase /FL=gb:AF327434.1 gb:AB020645.1 gb:AF097493.1 gb:AF223943.1 gb:NM_014905.1" AF097493 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203159_at NM_014905 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014905.1 /DEF=Homo sapiens glutaminase (GLS), mRNA. /FEA=mRNA /GEN=GLS /PROD=glutaminase C /DB_XREF=gi:7662327 /UG=Hs.239189 glutaminase /FL=gb:AF327434.1 gb:AB020645.1 gb:AF097493.1 gb:AF223943.1 gb:NM_014905.1" NM_014905 glutaminase GLS 2744 NM_001256310 /// NM_014905 /// XM_005246467 /// XM_006712435 /// XM_006712436 /// XR_241306 0001967 // suckling behavior // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006537 // glutamate biosynthetic process // inferred from direct assay /// 0006537 // glutamate biosynthetic process // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0006543 // glutamine catabolic process // inferred from direct assay /// 0006543 // glutamine catabolic process // non-traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0004359 // glutaminase activity // inferred from direct assay /// 0004359 // glutaminase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203160_s_at AK022075 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK022075.1 /DEF=Homo sapiens cDNA FLJ12013 fis, clone HEMBB1001673, highly similar to Homo sapiens gene for new zinc finger protein. /FEA=mRNA /DB_XREF=gi:10433395 /UG=Hs.24439 ring finger protein (C3HC4 type) 8 /FL=gb:AB014546.1 gb:NM_003958.1" AK022075 "ring finger protein 8, E3 ubiquitin protein ligase" RNF8 9025 NM_003958 /// NM_183078 /// NR_046399 /// XM_006715241 /// XM_006715242 /// XM_006715243 /// XR_427852 /// XR_427853 /// XR_427854 /// XR_427855 /// XR_427856 /// XR_427857 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from sequence or structural similarity /// 0036297 // interstrand cross-link repair // traceable author statement /// 0043486 // histone exchange // inferred from sequence or structural similarity /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045900 // negative regulation of translational elongation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay "0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay" 0003682 // chromatin binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203161_s_at NM_003958 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003958.1 /DEF=Homo sapiens ring finger protein (C3HC4 type) 8 (RNF8), mRNA. /FEA=mRNA /GEN=RNF8 /PROD=ring finger protein (C3HC4 type) 8 /DB_XREF=gi:4504866 /UG=Hs.24439 ring finger protein (C3HC4 type) 8 /FL=gb:AB014546.1 gb:NM_003958.1" NM_003958 "ring finger protein 8, E3 ubiquitin protein ligase" RNF8 9025 NM_003958 /// NM_183078 /// NR_046399 /// XM_006715241 /// XM_006715242 /// XM_006715243 /// XR_427852 /// XR_427853 /// XR_427854 /// XR_427855 /// XR_427856 /// XR_427857 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from direct assay /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from sequence or structural similarity /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0010212 // response to ionizing radiation // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0033522 // histone H2A ubiquitination // inferred from direct assay /// 0033523 // histone H2B ubiquitination // inferred from sequence or structural similarity /// 0036297 // interstrand cross-link repair // traceable author statement /// 0043486 // histone exchange // inferred from sequence or structural similarity /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045739 // positive regulation of DNA repair // inferred from direct assay /// 0045900 // negative regulation of translational elongation // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from direct assay /// 0070535 // histone H2A K63-linked ubiquitination // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay "0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0035861 // site of double-strand break // inferred from direct assay" 0003682 // chromatin binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203162_s_at NM_005886 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005886.1 /DEF=Homo sapiens katanin p80 (WD40-containing) subunit B 1 (KATNB1), mRNA. /FEA=mRNA /GEN=KATNB1 /PROD=katanin p80 subunit B 1 /DB_XREF=gi:5031816 /UG=Hs.275675 katanin p80 (WD40-containing) subunit B 1 /FL=gb:BC001353.1 gb:AF052432.1 gb:NM_005886.1" NM_005886 katanin p80 (WD repeat containing) subunit B 1 KATNB1 10300 NM_005886 /// XM_005255772 /// XM_006721121 /// XM_006721122 /// XM_006721123 0006200 // ATP catabolic process // inferred from direct assay /// 0006605 // protein targeting // non-traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007079 // mitotic chromosome movement towards spindle pole // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0031117 // positive regulation of microtubule depolymerization // inferred from mutant phenotype /// 0051013 // microtubule severing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0008352 // katanin complex // inferred from direct assay /// 0008352 // katanin complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // non-traceable author statement /// 0008568 // microtubule-severing ATPase activity // inferred from direct assay /// 0045502 // dynein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203163_at NM_005886 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005886.1 /DEF=Homo sapiens katanin p80 (WD40-containing) subunit B 1 (KATNB1), mRNA. /FEA=mRNA /GEN=KATNB1 /PROD=katanin p80 subunit B 1 /DB_XREF=gi:5031816 /UG=Hs.275675 katanin p80 (WD40-containing) subunit B 1 /FL=gb:BC001353.1 gb:AF052432.1 gb:NM_005886.1" NM_005886 katanin p80 (WD repeat containing) subunit B 1 KATNB1 10300 NM_005886 /// XM_005255772 /// XM_006721121 /// XM_006721122 /// XM_006721123 0006200 // ATP catabolic process // inferred from direct assay /// 0006605 // protein targeting // non-traceable author statement /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007079 // mitotic chromosome movement towards spindle pole // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0031117 // positive regulation of microtubule depolymerization // inferred from mutant phenotype /// 0051013 // microtubule severing // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0008352 // katanin complex // inferred from direct assay /// 0008352 // katanin complex // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // non-traceable author statement /// 0008568 // microtubule-severing ATPase activity // inferred from direct assay /// 0045502 // dynein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203164_at BE464756 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE464756 /FEA=EST /DB_XREF=gi:9510618 /DB_XREF=est:hv89d09.x1 /CLONE=IMAGE:3180593 /UG=Hs.285176 acetyl-Coenzyme A transporter /FL=gb:D88152.1 gb:NM_004733.2 BE464756 "solute carrier family 33 (acetyl-CoA transporter), member 1" SLC33A1 9197 NM_001190992 /// NM_004733 /// XM_006713822 0006810 // transport // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008521 // acetyl-CoA transporter activity // inferred from electronic annotation 203165_s_at NM_004733 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004733.2 /DEF=Homo sapiens acetyl-Coenzyme A transporter (ACATN), mRNA. /FEA=mRNA /GEN=ACATN /PROD=acetyl-Coenzyme A transporter /DB_XREF=gi:6042194 /UG=Hs.285176 acetyl-Coenzyme A transporter /FL=gb:D88152.1 gb:NM_004733.2" NM_004733 "solute carrier family 33 (acetyl-CoA transporter), member 1" SLC33A1 9197 NM_001190992 /// NM_004733 /// XM_006713822 0006810 // transport // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // inferred from electronic annotation /// 0015876 // acetyl-CoA transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008521 // acetyl-CoA transporter activity // inferred from electronic annotation 203166_at NM_006324 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006324.1 /DEF=Homo sapiens craniofacial development protein 1 (CFDP1), mRNA. /FEA=mRNA /GEN=CFDP1 /PROD=craniofacial development protein 1 /DB_XREF=gi:5453566 /UG=Hs.296460 craniofacial development protein 1 /FL=gb:BC000991.2 gb:AB009285.1 gb:NM_006324.1" NM_006324 craniofacial development protein 1 CFDP1 10428 NM_006324 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation 203167_at NM_003255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003255.2 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 2 (TIMP2), mRNA. /FEA=mRNA /GEN=TIMP2 /PROD=tissue inhibitor of metalloproteinase 2precursor /DB_XREF=gi:9257247 /UG=Hs.325495 tissue inhibitor of metalloproteinase 2 /FL=gb:M32304.1 gb:J05593.1 gb:NM_003255.2" NM_003255 TIMP metallopeptidase inhibitor 2 TIMP2 7077 NM_003255 0007417 // central nervous system development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030814 // regulation of cAMP metabolic process // inferred from electronic annotation /// 0032487 // regulation of Rap protein signal transduction // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043408 // regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045762 // positive regulation of adenylate cyclase activity // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031514 // motile cilium // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203168_at NM_004381 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004381.1 /DEF=Homo sapiens cAMP responsive element binding protein-like 1 (CREBL1), mRNA. /FEA=mRNA /GEN=CREBL1 /PROD=cAMP responsive element binding protein-like 1 /DB_XREF=gi:4758057 /UG=Hs.42853 cAMP responsive element binding protein-like 1 /FL=gb:U31903.1 gb:NM_004381.1" NM_004381 activating transcription factor 6 beta ATF6B 1388 NM_001136153 /// NM_004381 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement" 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203169_at NM_014785 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014785.1 /DEF=Homo sapiens KIAA0258 gene product (KIAA0258), mRNA. /FEA=mRNA /GEN=KIAA0258 /PROD=KIAA0258 gene product /DB_XREF=gi:7662029 /UG=Hs.47313 KIAA0258 gene product /FL=gb:BC001725.1 gb:D87447.1 gb:NM_014785.1" NM_014785 RGP1 retrograde golgi transport homolog (S. cerevisiae) RGP1 9827 NM_001080496 /// XM_006716895 203170_at AB007869 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB007869.1 /DEF=Homo sapiens KIAA0409 mRNA, partial cds. /FEA=mRNA /GEN=KIAA0409 /DB_XREF=gi:2662098 /UG=Hs.5158 KIAA0409 protein /FL=gb:BC001071.1 gb:NM_015324.1" AB007869 "ribosomal RNA processing 8, methyltransferase, homolog (yeast)" RRP8 23378 NM_015324 "0000183 // chromatin silencing at rDNA // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0046015 // regulation of transcription by glucose // inferred from mutant phenotype /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0033553 // rDNA heterochromatin // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 203171_s_at NM_015324 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015324.1 /DEF=Homo sapiens KIAA0409 protein (KIAA0409), mRNA. /FEA=mRNA /GEN=KIAA0409 /PROD=KIAA0409 protein /DB_XREF=gi:12758124 /UG=Hs.5158 KIAA0409 protein /FL=gb:BC001071.1 gb:NM_015324.1" NM_015324 "ribosomal RNA processing 8, methyltransferase, homolog (yeast)" RRP8 23378 NM_015324 "0000183 // chromatin silencing at rDNA // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0046015 // regulation of transcription by glucose // inferred from mutant phenotype /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005677 // chromatin silencing complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0033553 // rDNA heterochromatin // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 203172_at NM_004860 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004860.2 /DEF=Homo sapiens fragile X mental retardation, autosomal homolog 2 (FXR2), mRNA. /FEA=mRNA /GEN=FXR2 /PROD=fragile X mental retardation syndrome relatedprotein 2 /DB_XREF=gi:6598321 /UG=Hs.52788 fragile X mental retardation, autosomal homolog 2 /FL=gb:U31501.1 gb:NM_004860.2" NM_004860 "fragile X mental retardation, autosomal homolog 2" FXR2 9513 NM_004860 /// XR_243572 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203173_s_at AW080196 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW080196 /FEA=EST /DB_XREF=gi:6035348 /DB_XREF=est:xe49g08.x1 /CLONE=IMAGE:2611262 /UG=Hs.5320 hypothetical protein /FL=gb:NM_020314.1 gb:AL136744.1 AW080196 chromosome 16 open reading frame 62 C16orf62 57020 NM_020314 /// XM_005255435 /// XM_005255436 /// XM_006721065 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203174_s_at NM_003224 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003224.1 /DEF=Homo sapiens ADP-ribosylation factor related protein 1 (ARFRP1), mRNA. /FEA=mRNA /GEN=ARFRP1 /PROD=ADP-ribosylation factor related protein 1 /DB_XREF=gi:4507448 /UG=Hs.64904 ADP-ribosylation factor related protein 1 /FL=gb:NM_003224.1" NM_003224 ADP-ribosylation factor related protein 1 ARFRP1 10139 NM_001134758 /// NM_001267544 /// NM_001267545 /// NM_001267546 /// NM_001267547 /// NM_001267548 /// NM_001267549 /// NM_003224 /// NR_051954 /// NR_051955 /// NR_051956 /// NR_051957 /// NR_051958 "0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0034067 // protein localization to Golgi apparatus // inferred from mutant phenotype /// 0042147 // retrograde transport, endosome to Golgi // inferred from mutant phenotype /// 0043001 // Golgi to plasma membrane protein transport // inferred from mutant phenotype" 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203175_at NM_001665 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001665.1 /DEF=Homo sapiens ras homolog gene family, member G (rho G) (ARHG), mRNA. /FEA=mRNA /GEN=ARHG /PROD=ras homolog gene family, member G (rho G) /DB_XREF=gi:4502218 /UG=Hs.75082 ras homolog gene family, member G (rho G) /FL=gb:NM_001665.1" NM_001665 ras homolog family member G RHOG 391 NM_001665 /// XM_005252916 "0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from direct assay /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype" 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203176_s_at BE552470 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE552470 /FEA=EST /DB_XREF=gi:9794162 /DB_XREF=est:hw27d09.x1 /CLONE=IMAGE:3184145 /UG=Hs.75133 transcription factor 6-like 1 (mitochondrial transcription factor 1-like) /FL=gb:M62810.1 gb:NM_003201.1 BE552470 "transcription factor A, mitochondrial" TFAM 7019 NM_001270782 /// NM_003201 /// NM_012251 /// NR_073073 "0006261 // DNA-dependent DNA replication // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // inferred from direct assay /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033108 // mitochondrial respiratory chain complex assembly // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070363 // mitochondrial light strand promoter sense binding // inferred from direct assay" 203177_x_at NM_003201 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003201.1 /DEF=Homo sapiens transcription factor 6-like 1 (mitochondrial transcription factor 1-like) (TCF6L1), mRNA. /FEA=mRNA /GEN=TCF6L1 /PROD=transcription factor 6-like 1 (mitochondrialtranscription factor 1-like) /DB_XREF=gi:4507400 /UG=Hs.75133 transcription factor 6-like 1 (mitochondrial transcription factor 1-like) /FL=gb:M62810.1 gb:NM_003201.1" NM_003201 "transcription factor A, mitochondrial" TFAM 7019 NM_001270782 /// NM_003201 /// NM_012251 /// NR_073073 "0006261 // DNA-dependent DNA replication // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // traceable author statement /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // inferred from direct assay /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0033108 // mitochondrial respiratory chain complex assembly // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070363 // mitochondrial light strand promoter sense binding // inferred from direct assay" 203178_at NM_001482 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001482.1 /DEF=Homo sapiens glycine amidinotransferase (L-arginine:glycine amidinotransferase) (GATM), mRNA. /FEA=mRNA /GEN=GATM /PROD=glycine amidinotransferase (L-arginine:glycineamidinotransferase) /DB_XREF=gi:4503932 /UG=Hs.75335 glycine amidinotransferase (L-arginine:glycine amidinotransferase) /FL=gb:BC004141.1 gb:NM_001482.1" NM_001482 glycine amidinotransferase (L-arginine:glycine amidinotransferase) GATM 2628 NM_001482 /// XR_424635 /// XR_429525 /// XR_433091 0006600 // creatine metabolic process // traceable author statement /// 0006601 // creatine biosynthetic process // inferred from direct assay /// 0006601 // creatine biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0015067 // amidinotransferase activity // inferred from electronic annotation /// 0015068 // glycine amidinotransferase activity // inferred from direct assay /// 0015068 // glycine amidinotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation" 203179_at NM_000155 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000155.1 /DEF=Homo sapiens galactose-1-phosphate uridylyltransferase (GALT), mRNA. /FEA=mRNA /GEN=GALT /PROD=galactose-1-phosphate uridylyltransferase /DB_XREF=gi:4557614 /UG=Hs.75641 galactose-1-phosphate uridylyltransferase /FL=gb:M60091.1 gb:NM_000155.1" NM_000155 galactose-1-phosphate uridylyltransferase GALT 2592 NM_000155 /// NM_001258332 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // traceable author statement /// 0006258 // UDP-glucose catabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019388 // galactose catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0008108 // UDP-glucose:hexose-1-phosphate uridylyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0046316 // gluconokinase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203180_at NM_000693 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000693.1 /DEF=Homo sapiens aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), mRNA. /FEA=mRNA /GEN=ALDH1A3 /PROD=aldehyde dehydrogenase 1A3 /DB_XREF=gi:4502040 /UG=Hs.75746 aldehyde dehydrogenase 1 family, member A3 /FL=gb:NM_000693.1 gb:U07919.1" NM_000693 "aldehyde dehydrogenase 1 family, member A3" ALDH1A3 220 NM_000693 /// NM_001037224 /// NM_001293815 /// XR_109231 /// XR_111558 /// XR_172102 /// XR_243247 /// XR_248182 /// XR_253467 0002072 // optic cup morphogenesis involved in camera-type eye development // inferred from electronic annotation /// 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021768 // nucleus accumbens development // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay "0004029 // aldehyde dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation" 203181_x_at AW149364 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW149364 /FEA=EST /DB_XREF=gi:6197260 /DB_XREF=est:xf36c05.x1 /CLONE=IMAGE:2620136 /UG=Hs.78353 SFRS protein kinase 2 /FL=gb:U88666.1 gb:NM_003138.1 AW149364 SRSF protein kinase 2 SRPK2 6733 NM_001278273 /// NM_182691 /// NM_182692 /// XM_005250549 /// XM_005250550 /// XM_005250551 /// XM_006716098 "0000245 // spliceosomal complex assembly // inferred from direct assay /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035063 // nuclear speck organization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071889 // 14-3-3 protein binding // inferred from sequence or structural similarity" 203182_s_at NM_003138 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003138.1 /DEF=Homo sapiens SFRS protein kinase 2 (SRPK2), mRNA. /FEA=mRNA /GEN=SRPK2 /PROD=SFRS protein kinase 2 /DB_XREF=gi:4507220 /UG=Hs.78353 SFRS protein kinase 2 /FL=gb:U88666.1 gb:NM_003138.1" NM_003138 SRSF protein kinase 2 SRPK2 6733 NM_001278273 /// NM_182691 /// NM_182692 /// XM_005250549 /// XM_005250550 /// XM_005250551 /// XM_006716098 "0000245 // spliceosomal complex assembly // inferred from direct assay /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008380 // RNA splicing // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035063 // nuclear speck organization // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred by curator /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0048024 // regulation of mRNA splicing, via spliceosome // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0071889 // 14-3-3 protein binding // inferred from sequence or structural similarity" 203183_s_at NM_003076 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003076.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 (SMARCD1), mRNA. /FEA=mRNA /GEN=SMARCD1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily d, member 1 /DB_XREF=gi:4507082 /UG=Hs.79335 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 /FL=gb:U66617.1 gb:NM_003076.1" NM_003076 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" SMARCD1 6602 NM_003076 /// NM_139071 /// XM_005269107 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032947 // protein complex scaffold // inferred from direct assay 203184_at NM_001999 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001999.2 /DEF=Homo sapiens fibrillin 2 (congenital contractural arachnodactyly) (FBN2), mRNA. /FEA=mRNA /GEN=FBN2 /PROD=fibrillin 2 /DB_XREF=gi:4755135 /UG=Hs.79432 fibrillin 2 (congenital contractural arachnodactyly) /FL=gb:U03272.1 gb:NM_001999.2" NM_001999 fibrillin 2 FBN2 2201 NM_001999 0009653 // anatomical structure morphogenesis // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030501 // positive regulation of bone mineralization // inferred from sequence or structural similarity /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035583 // sequestering of TGFbeta in extracellular matrix // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0060346 // bone trabecula formation // inferred from sequence or structural similarity 0001527 // microfibril // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203185_at NM_014737 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014737.1 /DEF=Homo sapiens Ras association (RalGDSAF-6) domain family 2 (RASSF2), mRNA. /FEA=mRNA /GEN=RASSF2 /PROD=Ras association (RalGDSAF-6) domain family 2 /DB_XREF=gi:7661963 /UG=Hs.80905 Ras association (RalGDSAF-6) domain family 2 /FL=gb:D79990.1 gb:NM_014737.1" NM_014737 Ras association (RalGDS/AF-6) domain family member 2 RASSF2 9770 NM_014737 /// NM_170774 /// XM_005260895 /// XM_006723668 /// XM_006723669 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203186_s_at NM_002961 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002961.2 /DEF=Homo sapiens S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) (S100A4), transcript variant 1, mRNA. /FEA=mRNA /GEN=S100A4 /PROD=S100 calcium-binding protein A4 /DB_XREF=gi:9845514 /UG=Hs.81256 S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) /FL=gb:NM_002961.2 gb:NM_019554.1" NM_002961 S100 calcium binding protein A4 S100A4 6275 NM_002961 /// NM_019554 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050786 // RAGE receptor binding // inferred from physical interaction 203187_at NM_001380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001380.1 /DEF=Homo sapiens dedicator of cyto-kinesis 1 (DOCK1), mRNA. /FEA=mRNA /GEN=DOCK1 /PROD=dedicator of cyto-kinesis 1 /DB_XREF=gi:4503354 /UG=Hs.82295 dedicator of cyto-kinesis 1 /FL=gb:D50857.1 gb:NM_001380.1" NM_001380 dedicator of cytokinesis 1 DOCK1 1793 NM_001290223 /// NM_001380 /// XM_006717681 /// XM_006717682 /// XM_006717683 "0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation 203188_at NM_006876 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006876.1 /DEF=Homo sapiens i-beta-1,3-N-acetylglucosaminyltransferase (BETA3GNTI), mRNA. /FEA=mRNA /GEN=BETA3GNTI /PROD=i-beta-1,3-N-acetylglucosaminyltransferase /DB_XREF=gi:5802983 /UG=Hs.8526 i-beta-1,3-N-acetylglucosaminyltransferase /FL=gb:AF029893.1 gb:NM_006876.1" NM_006876 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1" B3GNT1 11041 NM_006876 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030311 // poly-N-acetyllactosamine biosynthetic process // inferred from direct assay /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0008532 // N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation" 203189_s_at NM_002496 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002496.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) (NDUFS8), mRNA. /FEA=mRNA /GEN=NDUFS8 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 8(23kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4505370 /UG=Hs.90443 NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) /FL=gb:U65579.1 gb:NM_002496.1" NM_002496 "microRNA 4691 /// microRNA 7113 /// NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)" MIR4691 /// MIR7113 /// NDUFS8 4728 /// 100616403 /// 102465669 NM_002496 /// NR_039840 /// NR_106963 /// XM_005274013 /// XM_005274014 /// XM_005274015 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation "0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation" 203190_at NM_002496 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002496.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) (NDUFS8), mRNA. /FEA=mRNA /GEN=NDUFS8 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 8(23kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4505370 /UG=Hs.90443 NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Q reductase) /FL=gb:U65579.1 gb:NM_002496.1" NM_002496 "microRNA 4691 /// microRNA 7113 /// NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)" MIR4691 /// MIR7113 /// NDUFS8 4728 /// 100616403 /// 102465669 NM_002496 /// NR_039840 /// NR_106963 /// XM_005274013 /// XM_005274014 /// XM_005274015 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0022904 // respiratory electron transport chain // traceable author statement /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // inferred from mutant phenotype /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation "0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from mutant phenotype /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation" 203191_at AF308472 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF308472.1 /DEF=Homo sapiens ATP-binding cassette half-transporter (PRP) mRNA, complete cds. /FEA=mRNA /GEN=PRP /PROD=ATP-binding cassette half-transporter /DB_XREF=gi:11245443 /UG=Hs.107911 ATP-binding cassette, sub-family B (MDRTAP), member 6 /FL=gb:AF308472.1 gb:BC000559.1 gb:AF076775.1 gb:NM_005689.1" AF308472 "ATP-binding cassette, sub-family B (MDR/TAP), member 6" ABCB6 10058 NM_005689 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015886 // heme transport // inferred from direct assay /// 0015886 // heme transport // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0015232 // heme transporter activity // traceable author statement /// 0015439 // heme-transporting ATPase activity // inferred from mutant phenotype /// 0015562 // efflux transmembrane transporter activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation" 203192_at NM_005689 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005689.1 /DEF=Homo sapiens ATP-binding cassette, sub-family B (MDRTAP), member 6 (ABCB6), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ABCB6 /PROD=ATP-binding cassette, sub-family B, member 6 /DB_XREF=gi:9955962 /UG=Hs.107911 ATP-binding cassette, sub-family B (MDRTAP), member 6 /FL=gb:AF308472.1 gb:BC000559.1 gb:AF076775.1 gb:NM_005689.1" NM_005689 "ATP-binding cassette, sub-family B (MDR/TAP), member 6" ABCB6 10058 NM_005689 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0000422 // mitochondrion degradation // not recorded /// 0000422 // mitochondrion degradation // /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from direct assay /// 0006810 // transport // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // non-traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015886 // heme transport // inferred from direct assay /// 0015886 // heme transport // inferred from mutant phenotype /// 0034067 // protein localization to Golgi apparatus // inferred from electronic annotation /// 0034497 // protein localization to pre-autophagosomal structure // not recorded /// 0034497 // protein localization to pre-autophagosomal structure // /// 0034727 // piecemeal microautophagy of nucleus // not recorded /// 0034727 // piecemeal microautophagy of nucleus // /// 0043588 // skin development // inferred from mutant phenotype /// 0044805 // late nucleophagy // not recorded /// 0044805 // late nucleophagy // /// 0045087 // innate immune response // inferred from electronic annotation /// 0055085 // transmembrane transport // not recorded /// 0055085 // transmembrane transport // traceable author statement /// 0070574 // cadmium ion transmembrane transport // /// 0071585 // detoxification of cadmium ion // 0000407 // pre-autophagosomal structure // not recorded /// 0000407 // pre-autophagosomal structure // /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from electronic annotation /// 0005774 // vacuolar membrane // /// 0005776 // autophagic vacuole // not recorded /// 0005776 // autophagic vacuole // /// 0005776 // autophagic vacuole // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // not recorded /// 0016021 // integral component of membrane // /// 0031307 // integral component of mitochondrial outer membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0015232 // heme transporter activity // traceable author statement /// 0015439 // heme-transporting ATPase activity // inferred from mutant phenotype /// 0015562 // efflux transmembrane transporter activity // inferred from direct assay /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation" 203193_at NM_004451 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004451.1 /DEF=Homo sapiens estrogen-related receptor alpha (ESRRA), mRNA. /FEA=mRNA /GEN=ESRRA /PROD=estrogen-related receptor alpha /DB_XREF=gi:4758305 /UG=Hs.110849 estrogen-related receptor alpha /FL=gb:NM_004451.1" NM_004451 estrogen-related receptor alpha ESRRA 2101 NM_001282450 /// NM_001282451 /// NM_004451 /// XM_006718449 /// XM_006718450 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051216 // cartilage development // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203194_s_at AA527238 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA527238 /FEA=EST /DB_XREF=gi:2269307 /DB_XREF=est:ng35e10.s1 /CLONE=IMAGE:936810 /UG=Hs.112255 nucleoporin 98kD /FL=gb:NM_005387.2 gb:AF071076.1 AA527238 nucleoporin 98kDa NUP98 4928 NM_005387 /// NM_016320 /// NM_139131 /// NM_139132 /// XM_005252950 /// XM_006718240 /// XM_006718241 /// XM_006718242 /// XR_428845 "0000059 // protein import into nucleus, docking // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006999 // nuclear pore organization // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement" 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype /// 0017056 // structural constituent of nuclear pore // non-traceable author statement /// 0042277 // peptide binding // inferred from electronic annotation 203195_s_at NM_005387 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005387.2 /DEF=Homo sapiens nucleoporin 98kD (NUP98), mRNA. /FEA=mRNA /GEN=NUP98 /PROD=nucleoporin 98kD /DB_XREF=gi:11120677 /UG=Hs.112255 nucleoporin 98kD /FL=gb:NM_005387.2 gb:AF071076.1" NM_005387 nucleoporin 98kDa NUP98 4928 NM_005387 /// NM_016320 /// NM_139131 /// NM_139132 /// XM_005252950 /// XM_006718240 /// XM_006718241 /// XM_006718242 /// XR_428845 "0000059 // protein import into nucleus, docking // non-traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006999 // nuclear pore organization // non-traceable author statement /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement" 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005643 // nuclear pore // inferred from direct assay /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031080 // nuclear pore outer ring // inferred from direct assay /// 0031080 // nuclear pore outer ring // non-traceable author statement /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017056 // structural constituent of nuclear pore // inferred from mutant phenotype /// 0017056 // structural constituent of nuclear pore // non-traceable author statement /// 0042277 // peptide binding // inferred from electronic annotation 203196_at AI948503 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI948503 /FEA=EST /DB_XREF=gi:5740813 /DB_XREF=est:wq06f10.x1 /CLONE=IMAGE:2470507 /UG=Hs.139336 ATP-binding cassette, sub-family C (CFTRMRP), member 4 /FL=gb:AF071202.1 gb:NM_005845.1" AI948503 "ATP-binding cassette, sub-family C (CFTR/MRP), member 4" ABCC4 10257 NM_001105515 /// NM_005845 /// XM_005254025 /// XM_006719914 0002576 // platelet degranulation // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // non-traceable author statement 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031088 // platelet dense granule membrane // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation" 203197_s_at AW157077 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW157077 /FEA=EST /DB_XREF=gi:6228478 /DB_XREF=est:au91f04.x1 /CLONE=IMAGE:2783647 /UG=Hs.146861 hypothetical protein FLJ20580 /FL=gb:NM_017887.1 AW157077 chromosome 1 open reading frame 123 C1orf123 54987 NM_017887 0070062 // extracellular vesicular exosome // inferred from direct assay 203198_at NM_001261 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001261.1 /DEF=Homo sapiens cyclin-dependent kinase 9 (CDC2-related kinase) (CDK9), mRNA. /FEA=mRNA /GEN=CDK9 /PROD=cyclin-dependent kinase 9 (CDC2-related kinase) /DB_XREF=gi:4502746 /UG=Hs.150423 cyclin-dependent kinase 9 (CDC2-related kinase) /FL=gb:BC001968.1 gb:NM_001261.1 gb:L25676.1" NM_001261 cyclin-dependent kinase 9 CDK9 1025 NM_001261 "0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031056 // regulation of histone modification // inferred from direct assay /// 0043111 // replication fork arrest // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008023 // transcription elongation factor complex // traceable author statement /// 0008024 // positive transcription elongation factor complex b // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017069 // snRNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation" 203199_s_at N29717 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N29717 /FEA=EST /DB_XREF=gi:1148237 /DB_XREF=est:yw78f05.s1 /CLONE=IMAGE:258369 /UG=Hs.153792 5-methyltetrahydrofolate-homocysteine methyltransferase reductase /FL=gb:NM_024010.1 gb:AF121214.1 N29717 5-methyltetrahydrofolate-homocysteine methyltransferase reductase MTRR 4552 NM_002454 /// NM_024010 /// XM_006714474 /// XR_241702 /// XR_241703 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006555 // methionine metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay "0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0010181 // FMN binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // not recorded /// 0016723 // oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor // inferred from direct assay /// 0030586 // [methionine synthase] reductase activity // traceable author statement /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // traceable author statement /// 0050661 // NADP binding // traceable author statement" 203200_s_at NM_024010 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024010.1 /DEF=Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2, mRNA. /FEA=mRNA /GEN=MTRR /PROD=methionine synthase reductase, isoform 2 /DB_XREF=gi:13325067 /UG=Hs.153792 5-methyltetrahydrofolate-homocysteine methyltransferase reductase /FL=gb:NM_024010.1 gb:AF121214.1" NM_024010 5-methyltetrahydrofolate-homocysteine methyltransferase reductase MTRR 4552 NM_002454 /// NM_024010 /// XM_006714474 /// XR_241702 /// XR_241703 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006306 // DNA methylation // inferred from sequence or structural similarity /// 0006555 // methionine metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046655 // folic acid metabolic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay "0003958 // NADPH-hemoprotein reductase activity // not recorded /// 0005506 // iron ion binding // inferred from electronic annotation /// 0010181 // FMN binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // not recorded /// 0016723 // oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor // inferred from direct assay /// 0030586 // [methionine synthase] reductase activity // traceable author statement /// 0050660 // flavin adenine dinucleotide binding // inferred from direct assay /// 0050660 // flavin adenine dinucleotide binding // traceable author statement /// 0050661 // NADP binding // traceable author statement" 203201_at NM_000303 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000303.1 /DEF=Homo sapiens phosphomannomutase 2 (PMM2), mRNA. /FEA=mRNA /GEN=PMM2 /PROD=phosphomannomutase 2 /DB_XREF=gi:4557838 /UG=Hs.154695 phosphomannomutase 2 /FL=gb:U85773.1 gb:NM_000303.1" NM_000303 phosphomannomutase 2 PMM2 5373 NM_000303 /// XM_005255372 /// XM_005255373 /// XM_005255374 0006486 // protein glycosylation // traceable author statement /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019307 // mannose biosynthetic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004615 // phosphomannomutase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 203202_at AI950314 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI950314 /FEA=EST /DB_XREF=gi:5742624 /DB_XREF=est:wp08c11.x1 /CLONE=IMAGE:2464244 /UG=Hs.154762 HIV-1 rev binding protein 2 /FL=gb:U55766.1 gb:NM_007043.1 AI950314 "KRR1, small subunit (SSU) processome component, homolog (yeast)" KRR1 11103 NM_007043 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203203_s_at NM_007043 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007043.1 /DEF=Homo sapiens HIV-1 rev binding protein 2 (HRB2), mRNA. /FEA=mRNA /GEN=HRB2 /PROD=HIV-1 rev binding protein 2 /DB_XREF=gi:5902047 /UG=Hs.154762 HIV-1 rev binding protein 2 /FL=gb:U55766.1 gb:NM_007043.1" NM_007043 "KRR1, small subunit (SSU) processome component, homolog (yeast)" KRR1 11103 NM_007043 0006364 // rRNA processing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203204_s_at BC002558 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002558.1 /DEF=Homo sapiens, KIAA0677 gene product, clone MGC:1972, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0677 gene product /DB_XREF=gi:12803466 /UG=Hs.155983 KIAA0677 gene product /FL=gb:BC002558.1 gb:AB014577.1 gb:NM_014663.1" BC002558 lysine (K)-specific demethylase 4A KDM4A 9682 NM_014663 /// XM_005271354 /// XM_005271355 /// XM_005271356 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016577 // histone demethylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay 203205_at NM_014663 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014663.1 /DEF=Homo sapiens KIAA0677 gene product (KIAA0677), mRNA. /FEA=mRNA /GEN=KIAA0677 /PROD=KIAA0677 gene product /DB_XREF=gi:7662245 /UG=Hs.155983 KIAA0677 gene product /FL=gb:BC002558.1 gb:AB014577.1 gb:NM_014663.1" NM_014663 lysine (K)-specific demethylase 4A KDM4A 9682 NM_014663 /// XM_005271354 /// XM_005271355 /// XM_005271356 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016577 // histone demethylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070544 // histone H3-K36 demethylation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0051864 // histone demethylase activity (H3-K36 specific) // inferred from direct assay 203206_at NM_014661 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014661.1 /DEF=Homo sapiens KIAA0140 gene product (KIAA0140), mRNA. /FEA=mRNA /GEN=KIAA0140 /PROD=KIAA0140 gene product /DB_XREF=gi:7661937 /UG=Hs.156016 KIAA0140 gene product /FL=gb:D50930.1 gb:NM_014661.1" NM_014661 "family with sequence similarity 53, member B" FAM53B 9679 NM_014661 203207_s_at BF214329 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF214329 /FEA=EST /DB_XREF=gi:11107915 /DB_XREF=est:601848574F1 /CLONE=IMAGE:4079202 /UG=Hs.170198 KIAA0009 gene product /FL=gb:D13634.1 gb:NM_014637.1 BF214329 mitochondrial fission regulator 1 MTFR1 9650 NM_001145838 /// NM_001145839 /// NM_014637 /// XM_005251327 /// XM_006716484 0000266 // mitochondrial fission // inferred from sequence or structural similarity /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0009060 // aerobic respiration // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 203208_s_at NM_014637 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014637.1 /DEF=Homo sapiens KIAA0009 gene product (KIAA0009), mRNA. /FEA=mRNA /GEN=KIAA0009 /PROD=KIAA0009 gene product /DB_XREF=gi:7661853 /UG=Hs.170198 KIAA0009 gene product /FL=gb:D13634.1 gb:NM_014637.1" NM_014637 mitochondrial fission regulator 1 MTFR1 9650 NM_001145838 /// NM_001145839 /// NM_014637 /// XM_005251327 /// XM_006716484 0000266 // mitochondrial fission // inferred from sequence or structural similarity /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0009060 // aerobic respiration // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 203209_at BC001866 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001866.1 /DEF=Homo sapiens, replication factor C (activator 1) 5 (36.5kD), clone MGC:1155, mRNA, complete cds. /FEA=mRNA /PROD=replication factor C (activator 1) 5 (36.5kD) /DB_XREF=gi:12804840 /UG=Hs.171075 replication factor C (activator 1) 5 (36.5kD) /FL=gb:BC001866.1 gb:L07540.1 gb:NM_007370.1" BC001866 "replication factor C (activator 1) 5, 36.5kDa" RFC5 5985 NM_001130112 /// NM_001130113 /// NM_001206801 /// NM_007370 /// NM_181578 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 203210_s_at NM_007370 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007370.1 /DEF=Homo sapiens replication factor C (activator 1) 5 (36.5kD) (RFC5), mRNA. /FEA=mRNA /GEN=RFC5 /PROD=replication factor C (activator 1) 5 (36.5kD) /DB_XREF=gi:6677722 /UG=Hs.171075 replication factor C (activator 1) 5 (36.5kD) /FL=gb:BC001866.1 gb:L07540.1 gb:NM_007370.1" NM_007370 "replication factor C (activator 1) 5, 36.5kDa" RFC5 5985 NM_001130112 /// NM_001130113 /// NM_001206801 /// NM_007370 /// NM_181578 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // non-traceable author statement 203211_s_at AK027038 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK027038.1 /DEF=Homo sapiens cDNA: FLJ23385 fis, clone HEP16802. /FEA=mRNA /DB_XREF=gi:10440053 /UG=Hs.181326 KIAA1073 protein /FL=gb:AB028996.1 gb:NM_016156.1" AK027038 myotubularin related protein 2 MTMR2 8898 NM_001243571 /// NM_016156 /// NM_201278 /// NM_201281 /// XM_005274374 /// XM_005274375 /// XM_006718933 /// XM_006718934 /// XM_006718935 /// XM_006718936 0002091 // negative regulation of receptor internalization // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from sequence or structural similarity /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097062 // dendritic spine maintenance // inferred from sequence or structural similarity /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from sequence or structural similarity /// 2000645 // negative regulation of receptor catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0052866 // phosphatidylinositol phosphate phosphatase activity // inferred from electronic annotation 203212_s_at NM_016156 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016156.1 /DEF=Homo sapiens KIAA1073 protein (KIAA1073), mRNA. /FEA=mRNA /GEN=KIAA1073 /PROD=KIAA1073 protein /DB_XREF=gi:7705563 /UG=Hs.181326 KIAA1073 protein /FL=gb:AB028996.1 gb:NM_016156.1" NM_016156 myotubularin related protein 2 MTMR2 8898 NM_001243571 /// NM_016156 /// NM_201278 /// NM_201281 /// XM_005274374 /// XM_005274375 /// XM_006718933 /// XM_006718934 /// XM_006718935 /// XM_006718936 0002091 // negative regulation of receptor internalization // inferred from sequence or structural similarity /// 0006470 // protein dephosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from sequence or structural similarity /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097062 // dendritic spine maintenance // inferred from sequence or structural similarity /// 2000643 // positive regulation of early endosome to late endosome transport // inferred from sequence or structural similarity /// 2000645 // negative regulation of receptor catabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity /// 0097481 // neuronal postsynaptic density // inferred from sequence or structural similarity 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0052866 // phosphatidylinositol phosphate phosphatase activity // inferred from electronic annotation 203213_at AL524035 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL524035 /FEA=EST /DB_XREF=gi:12787528 /DB_XREF=est:AL524035 /CLONE=CS0DC003YN06 (3 prime) /UG=Hs.184572 cell division cycle 2, G1 to S and G2 to M /FL=gb:NM_001786.1" AL524035 cyclin-dependent kinase 1 CDK1 983 NM_001130829 /// NM_001170406 /// NM_001170407 /// NM_001786 /// NM_033379 /// XM_005270303 /// XM_006718082 /// XM_006718083 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007098 // centrosome cycle // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007344 // pronuclear fusion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014038 // regulation of Schwann cell differentiation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045995 // regulation of embryonic development // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0035173 // histone kinase activity // inferred from electronic annotation" 203214_x_at NM_001786 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001786.1 /DEF=Homo sapiens cell division cycle 2, G1 to S and G2 to M (CDC2), mRNA. /FEA=mRNA /GEN=CDC2 /PROD=cell division cycle 2, G1 to S and G2 to M /DB_XREF=gi:4502708 /UG=Hs.184572 cell division cycle 2, G1 to S and G2 to M /FL=gb:NM_001786.1" NM_001786 cyclin-dependent kinase 1 CDK1 983 NM_001130829 /// NM_001170406 /// NM_001170407 /// NM_001786 /// NM_033379 /// XM_005270303 /// XM_006718082 /// XM_006718083 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from electronic annotation /// 0007098 // centrosome cycle // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007344 // pronuclear fusion // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014038 // regulation of Schwann cell differentiation // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // traceable author statement /// 0016572 // histone phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045995 // regulation of embryonic development // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048678 // response to axon injury // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from electronic annotation /// 0030544 // Hsp70 protein binding // inferred from electronic annotation /// 0035173 // histone kinase activity // inferred from electronic annotation" 203215_s_at AA877789 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA877789 /FEA=EST /DB_XREF=gi:2986754 /DB_XREF=est:nr06h10.s1 /CLONE=IMAGE:1161091 /UG=Hs.22564 myosin VI /FL=gb:AB002387.1 gb:NM_004999.1 AA877789 myosin VI MYO6 4646 NM_004999 /// XM_005248719 /// XM_005248720 /// XM_005248721 /// XM_005248722 /// XM_005248724 /// XM_005248725 /// XM_005248726 "0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // non-traceable author statement /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051046 // regulation of secretion // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation" "0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from sequence or structural similarity /// 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060001 // minus-end directed microfilament motor activity // non-traceable author statement 203216_s_at NM_004999 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004999.1 /DEF=Homo sapiens myosin VI (MYO6), mRNA. /FEA=mRNA /GEN=MYO6 /PROD=myosin VI /DB_XREF=gi:4826845 /UG=Hs.22564 myosin VI /FL=gb:AB002387.1 gb:NM_004999.1" NM_004999 myosin VI MYO6 4646 NM_004999 /// XM_005248719 /// XM_005248720 /// XM_005248721 /// XM_005248722 /// XM_005248724 /// XM_005248725 /// XM_005248726 "0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007416 // synapse assembly // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // non-traceable author statement /// 0014047 // glutamate secretion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016358 // dendrite development // inferred from electronic annotation /// 0030048 // actin filament-based movement // inferred from sequence or structural similarity /// 0030048 // actin filament-based movement // non-traceable author statement /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0051046 // regulation of secretion // inferred from mutant phenotype /// 0061024 // membrane organization // traceable author statement /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation" "0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // traceable author statement /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0030665 // clathrin-coated vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045334 // clathrin-coated endocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from sequence or structural similarity /// 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0043531 // ADP binding // inferred from sequence or structural similarity /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity /// 0060001 // minus-end directed microfilament motor activity // non-traceable author statement 203217_s_at NM_003896 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003896.1 /DEF=Homo sapiens sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) (SIAT9), mRNA. /FEA=mRNA /GEN=SIAT9 /PROD=sialyltransferase 9 (CMP-NeuAc:lactosylceramidealpha-2,3-sialyltransferase; GM3 synthase) /DB_XREF=gi:4506954 /UG=Hs.225939 sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) /FL=gb:AB018356.1 gb:NM_003896.1 gb:AF119415.1" NM_003896 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" ST3GAL5 8869 NM_001042437 /// NM_003896 /// XM_005264630 /// XM_006712127 /// XR_244967 /// XR_426999 0001574 // ganglioside biosynthetic process // non-traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation "0004513 // neolactotetraosylceramide alpha-2,3-sialyltransferase activity // traceable author statement /// 0008373 // sialyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047291 // lactosylceramide alpha-2,3-sialyltransferase activity // inferred from direct assay" 203218_at W37431 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:W37431 /FEA=EST /DB_XREF=gi:1319025 /DB_XREF=est:zc11f11.s1 /CLONE=IMAGE:322029 /UG=Hs.246857 mitogen-activated protein kinase 9 /FL=gb:U34821.1 gb:NM_002752.1 gb:L31951.1 gb:U09759.1 W37431 mitogen-activated protein kinase 9 MAPK9 5601 NM_001135044 /// NM_002752 /// NM_139068 /// NM_139069 /// NM_139070 /// XM_005265940 /// XM_006714891 "0000165 // MAPK cascade // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // inferred from direct assay /// 0007254 // JNK cascade // traceable author statement /// 0007258 // JUN phosphorylation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010770 // positive regulation of cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0031396 // regulation of protein ubiquitination // inferred from electronic annotation /// 0032308 // positive regulation of prostaglandin secretion // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034644 // cellular response to UV // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004705 // JUN kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation" 203219_s_at NM_000485 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000485.1 /DEF=Homo sapiens adenine phosphoribosyltransferase (APRT), mRNA. /FEA=mRNA /GEN=APRT /PROD=adenine phosphoribosyltransferase /DB_XREF=gi:4502170 /UG=Hs.28914 adenine phosphoribosyltransferase /FL=gb:NM_000485.1" NM_000485 adenine phosphoribosyltransferase APRT 353 NM_000485 /// NM_001030018 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006168 // adenine salvage // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044209 // AMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0002055 // adenine binding // inferred from electronic annotation /// 0003999 // adenine phosphoribosyltransferase activity // traceable author statement /// 0016208 // AMP binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation" 203220_s_at AI951720 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI951720 /FEA=EST /DB_XREF=gi:5744030 /DB_XREF=est:wv38f09.x1 /CLONE=IMAGE:2531849 /UG=Hs.28935 transducin-like enhancer of split 1, homolog of Drosophila E(sp1) /FL=gb:M99435.1 gb:NM_005077.1" AI951720 "transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)" TLE1 7088 NM_005077 /// XM_005252151 /// XM_005252152 /// XM_005252153 /// XM_005252154 /// XM_005252155 /// XM_005252156 /// XM_005252162 /// XM_005252163 /// XM_006717258 /// XM_006717259 /// XM_006717260 /// XM_006717261 /// XM_006717262 /// XM_006717263 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction 203221_at AI758763 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI758763 /FEA=EST /DB_XREF=gi:5152488 /DB_XREF=est:ty24a06.x1 /CLONE=IMAGE:2279986 /UG=Hs.28935 transducin-like enhancer of split 1, homolog of Drosophila E(sp1) /FL=gb:M99435.1 gb:NM_005077.1" AI758763 "transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)" TLE1 7088 NM_005077 /// XM_005252151 /// XM_005252152 /// XM_005252153 /// XM_005252154 /// XM_005252155 /// XM_005252156 /// XM_005252162 /// XM_005252163 /// XM_006717258 /// XM_006717259 /// XM_006717260 /// XM_006717261 /// XM_006717262 /// XM_006717263 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction 203222_s_at NM_005077 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005077.1 /DEF=Homo sapiens transducin-like enhancer of split 1, homolog of Drosophila E(sp1) (TLE1), mRNA. /FEA=mRNA /GEN=TLE1 /PROD=transducin-like enhancer of split 1, homolog ofDrosophila E(sp1) /DB_XREF=gi:4827027 /UG=Hs.28935 transducin-like enhancer of split 1, homolog of Drosophila E(sp1) /FL=gb:M99435.1 gb:NM_005077.1" NM_005077 "transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)" TLE1 7088 NM_005077 /// XM_005252151 /// XM_005252152 /// XM_005252153 /// XM_005252154 /// XM_005252155 /// XM_005252156 /// XM_005252162 /// XM_005252163 /// XM_006717258 /// XM_006717259 /// XM_006717260 /// XM_006717261 /// XM_006717262 /// XM_006717263 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // non-traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from mutant phenotype 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0008134 // transcription factor binding // inferred from physical interaction 203223_at NM_004703 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004703.1 /DEF=Homo sapiens rabaptin-5 (RAB5EP), mRNA. /FEA=mRNA /GEN=RAB5EP /PROD=rabaptin-5 /DB_XREF=gi:4759005 /UG=Hs.326056 rabaptin-5 /FL=gb:NM_004703.1" NM_004703 "rabaptin, RAB GTPase binding effector protein 1" RABEP1 9135 NM_001083585 /// NM_001291581 /// NM_001291582 /// NM_004703 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061025 // membrane fusion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055037 // recycling endosome // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 203224_at BF340123 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF340123 /FEA=EST /DB_XREF=gi:11286585 /DB_XREF=est:602037283F1 /CLONE=IMAGE:4185212 /UG=Hs.37558 hypothetical protein FLJ11149 /FL=gb:NM_018339.1 BF340123 riboflavin kinase RFK 55312 NM_018339 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0009231 // riboflavin biosynthetic process // non-traceable author statement /// 0009398 // FMN biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033864 // positive regulation of NAD(P)H oxidase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008531 // riboflavin kinase activity // non-traceable author statement /// 0008531 // riboflavin kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203225_s_at NM_018339 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018339.1 /DEF=Homo sapiens hypothetical protein FLJ11149 (FLJ11149), mRNA. /FEA=mRNA /GEN=FLJ11149 /PROD=hypothetical protein FLJ11149 /DB_XREF=gi:8922898 /UG=Hs.37558 hypothetical protein FLJ11149 /FL=gb:NM_018339.1" NM_018339 riboflavin kinase RFK 55312 NM_018339 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006771 // riboflavin metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0009231 // riboflavin biosynthetic process // non-traceable author statement /// 0009398 // FMN biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033864 // positive regulation of NAD(P)H oxidase activity // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008531 // riboflavin kinase activity // non-traceable author statement /// 0008531 // riboflavin kinase activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203226_s_at AL514076 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL514076 /FEA=EST /DB_XREF=gi:12777570 /DB_XREF=est:AL514076 /CLONE=CL0BA004ZB05 (5 prime) /UG=Hs.50984 sarcoma amplified sequence /FL=gb:U01160.1 gb:NM_005981.1 AL514076 tetraspanin 31 TSPAN31 6302 NM_005981 /// XM_005269074 0008284 // positive regulation of cell proliferation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 203227_s_at NM_005981 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005981.1 /DEF=Homo sapiens sarcoma amplified sequence (SAS), mRNA. /FEA=mRNA /GEN=SAS /PROD=sarcoma amplified sequence /DB_XREF=gi:5174666 /UG=Hs.50984 sarcoma amplified sequence /FL=gb:U01160.1 gb:NM_005981.1" NM_005981 tetraspanin 31 TSPAN31 6302 NM_005981 /// XM_005269074 0008284 // positive regulation of cell proliferation // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 203228_at NM_002573 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002573.1 /DEF=Homo sapiens platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit (29kD) (PAFAH1B3), mRNA. /FEA=mRNA /GEN=PAFAH1B3 /PROD=platelet-activating factor acetylhydrolase,isoform Ib, gamma subunit (29kD) /DB_XREF=gi:4505586 /UG=Hs.6793 platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit (29kD) /FL=gb:D63391.1 gb:BC003016.1 gb:NM_002573.1" NM_002573 "platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)" PAFAH1B3 5050 NM_001145939 /// NM_001145940 /// NM_002573 0006629 // lipid metabolic process // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003847 // 1-alkyl-2-acetylglycerophosphocholine esterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203229_s_at NM_003993 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003993.1 /DEF=Homo sapiens CDC-like kinase 2 (CLK2), transcript variant phclk2, mRNA. /FEA=mRNA /GEN=CLK2 /PROD=CDC-like kinase 2 isoform hclk2 /DB_XREF=gi:4502882 /UG=Hs.73986 CDC-like kinase 2 /FL=gb:NM_003993.1 gb:L29218.1" NM_003993 CDC-like kinase 2 CLK2 1196 NM_001291 /// NM_001294338 /// NM_001294339 /// NM_003993 /// XM_005244876 /// XM_005244878 /// XM_005244879 /// XM_005276742 /// XM_005276744 /// XM_005276745 /// XR_241067 /// XR_254196 0006468 // protein phosphorylation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203230_at AF006011 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF006011.1 /DEF=Homo sapiens dishevelled 1 (DVL1) mRNA, complete cds. /FEA=mRNA /GEN=DVL1 /PROD=dishevelled 1 /DB_XREF=gi:2291005 /UG=Hs.74375 dishevelled 1 (homologous to Drosophila dsh) /FL=gb:U46461.1 gb:AF006011.1 gb:NM_004421.1" AF006011 dishevelled segment polarity protein 1 DVL1 1855 NM_004421 /// NM_181870 /// NM_182779 /// XM_005244731 /// XM_005244732 /// XM_005244733 "0001505 // regulation of neurotransmitter levels // inferred from sequence or structural similarity /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0007269 // neurotransmitter secretion // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0007507 // heart development // non-traceable author statement /// 0007528 // neuromuscular junction development // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021915 // neural tube development // inferred from expression pattern /// 0022007 // convergent extension involved in neural plate elongation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0035176 // social behavior // inferred from electronic annotation /// 0035372 // protein localization to microtubule // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048668 // collateral sprouting // not recorded /// 0048675 // axon extension // not recorded /// 0048813 // dendrite morphogenesis // not recorded /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from sequence or structural similarity /// 0060026 // convergent extension // not recorded /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from direct assay /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // not recorded /// 0090103 // cochlea morphogenesis // not recorded /// 0090179 // planar cell polarity pathway involved in neural tube closure // not recorded /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005874 // microtubule // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // not recorded /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030136 // clathrin-coated vesicle // not recorded /// 0030424 // axon // not recorded /// 0030425 // dendrite // not recorded /// 0030426 // growth cone // not recorded /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043025 // neuronal cell body // not recorded /// 0045202 // synapse // not recorded /// 0045202 // synapse // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0048365 // Rac GTPase binding // not recorded 203231_s_at AW235612 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW235612 /FEA=EST /DB_XREF=gi:6568001 /DB_XREF=est:xn20e02.x1 /CLONE=IMAGE:2694266 /UG=Hs.74520 spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1) /FL=gb:NM_000332.1" AW235612 ataxin 1 ATXN1 6310 NM_000332 /// NM_001128164 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0042272 // nuclear RNA export factor complex // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay 203232_s_at NM_000332 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000332.1 /DEF=Homo sapiens spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1) (SCA1), mRNA. /FEA=mRNA /GEN=SCA1 /PROD=ataxin 1 /DB_XREF=gi:4506792 /UG=Hs.74520 spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1) /FL=gb:NM_000332.1" NM_000332 ataxin 1 ATXN1 6310 NM_000332 /// NM_001128164 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from direct assay /// 0042272 // nuclear RNA export factor complex // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008266 // poly(U) RNA binding // inferred from direct assay /// 0034046 // poly(G) binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from direct assay 203233_at NM_000418 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000418.1 /DEF=Homo sapiens interleukin 4 receptor (IL4R), mRNA. /FEA=mRNA /GEN=IL4R /PROD=interleukin 4 receptor precursor /DB_XREF=gi:4557668 /UG=Hs.75545 interleukin 4 receptor /FL=gb:NM_000418.1" NM_000418 interleukin 4 receptor IL4R 3566 NM_000418 /// NM_001008699 /// NM_001257406 /// NM_001257407 /// NM_001257997 /// XM_005255305 /// XM_005255308 /// XM_005255309 /// XM_006721043 0002376 // immune system process // inferred from electronic annotation /// 0002532 // production of molecular mediator involved in inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0035771 // interleukin-4-mediated signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0043032 // positive regulation of macrophage activation // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045626 // negative regulation of T-helper 1 cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from electronic annotation /// 0090197 // positive regulation of chemokine secretion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004913 // interleukin-4 receptor activity // traceable author statement /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from reviewed computational analysis 203234_at NM_003364 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003364.1 /DEF=Homo sapiens uridine phosphorylase (UP), mRNA. /FEA=mRNA /GEN=UP /PROD=uridine phosphorylase /DB_XREF=gi:4507838 /UG=Hs.77573 uridine phosphorylase /FL=gb:BC001405.1 gb:NM_003364.1" NM_003364 uridine phosphorylase 1 UPP1 7378 NM_001287426 /// NM_001287428 /// NM_001287429 /// NM_001287430 /// NM_003364 /// NM_181597 /// NR_109837 /// XM_005249838 /// XM_006715771 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009166 // nucleotide catabolic process // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044206 // UMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046108 // uridine metabolic process // inferred from electronic annotation /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0003824 // catalytic activity // inferred from electronic annotation /// 0004850 // uridine phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation" 203235_at NM_003249 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003249.1 /DEF=Homo sapiens thimet oligopeptidase 1 (THOP1), mRNA. /FEA=mRNA /GEN=THOP1 /PROD=thimet oligopeptidase 1 /DB_XREF=gi:4507490 /UG=Hs.78769 thimet oligopeptidase 1 /FL=gb:U29366.1 gb:BC000583.1 gb:BC002391.1 gb:BC000135.2 gb:NM_003249.1" NM_003249 thimet oligopeptidase 1 THOP1 7064 NM_003249 0006508 // proteolysis // inferred from electronic annotation /// 0006518 // peptide metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203236_s_at NM_009587 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_009587.1 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 9 (galectin 9) (LGALS9), transcript variant long, mRNA. /FEA=mRNA /GEN=LGALS9 /PROD=galectin 9, long isoform /DB_XREF=gi:6806889 /UG=Hs.81337 lectin, galactoside-binding, soluble, 9 (galectin 9) /FL=gb:AB006782.1 gb:NM_009587.1" NM_009587 "lectin, galactoside-binding, soluble, 9" LGALS9 3965 NM_002308 /// NM_009587 /// NR_024043 /// XM_006721892 /// XM_006721893 /// XM_006721894 /// XM_006721895 0007165 // signal transduction // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005534 // galactose binding // traceable author statement /// 0030246 // carbohydrate binding // inferred from direct assay 203237_s_at AW139152 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW139152 /FEA=EST /DB_XREF=gi:6143470 /DB_XREF=est:UI-H-BI1-aet-c-11-0-UI.s1 /CLONE=IMAGE:2720277 /UG=Hs.8546 Notch (Drosophila) homolog 3 /FL=gb:U97669.1 gb:NM_000435.1 AW139152 notch 3 NOTCH3 4854 NM_000435 /// XM_005259924 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0072104 // glomerular capillary formation // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 203238_s_at NM_000435 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000435.1 /DEF=Homo sapiens Notch (Drosophila) homolog 3 (NOTCH3), mRNA. /FEA=mRNA /GEN=NOTCH3 /PROD=Notch (Drosophila) homolog 3 /DB_XREF=gi:4557798 /UG=Hs.8546 Notch (Drosophila) homolog 3 /FL=gb:U97669.1 gb:NM_000435.1" NM_000435 notch 3 NOTCH3 4854 NM_000435 /// XM_005259924 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048663 // neuron fate commitment // inferred from electronic annotation /// 0050793 // regulation of developmental process // inferred from electronic annotation /// 0072104 // glomerular capillary formation // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from electronic annotation 203239_s_at NM_014516 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014516.1 /DEF=Homo sapiens CCR4-NOT transcription complex, subunit 3 (CNOT3), mRNA. /FEA=mRNA /GEN=CNOT3 /PROD=CCR4-NOT transcription complex, subunit 3 /DB_XREF=gi:7657386 /UG=Hs.108300 CCR4-NOT transcription complex, subunit 3 /FL=gb:AB014591.1 gb:NM_014516.1" NM_014516 "CCR4-NOT transcription complex, subunit 3" CNOT3 4849 NM_014516 /// XM_005258956 /// XM_005258957 /// XM_005258958 /// XM_005258959 /// XM_005277076 /// XM_005277077 /// XM_005277078 /// XM_005277079 /// XM_005277266 /// XM_005277267 /// XM_005277268 /// XM_005277269 /// XM_005278279 /// XM_005278280 /// XM_005278281 /// XM_005278282 /// XM_006725771 /// XM_006725772 /// XM_006725773 /// XM_006725774 /// XM_006725872 /// XM_006725873 /// XM_006725874 /// XM_006725875 /// XM_006725960 /// XM_006725961 /// XM_006725962 /// XM_006725963 /// XM_006726059 /// XM_006726060 /// XM_006726061 /// XM_006726062 /// XM_006726160 /// XM_006726161 /// XM_006726162 /// XM_006726163 /// XM_006726197 /// XM_006726198 /// XM_006726199 /// XM_006726200 /// XR_243935 /// XR_243936 /// XR_254258 /// XR_254259 /// XR_254309 /// XR_254310 /// XR_254515 /// XR_254516 /// XR_430951 /// XR_430952 /// XR_430984 /// XR_430985 /// XR_431004 /// XR_431005 /// XR_431023 /// XR_431024 /// XR_431054 /// XR_431055 /// XR_431065 /// XR_431066 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype" 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203240_at NM_003890 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:NM_003890.1 /DEF=Homo sapiens IgG Fc binding protein (FC(GAMMA)BP) mRNA. /FEA=mRNA /GEN=FC(GAMMA)BP /PROD=IgG Fc binding protein /DB_XREF=gi:4503680 /UG=Hs.111732 Fc fragment of IgG binding protein /FL=gb:D84239.1 gb:NM_003890.1 NM_003890 Fc fragment of IgG binding protein FCGBP 8857 NM_003890 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203241_at NM_003369 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003369.1 /DEF=Homo sapiens UV radiation resistance associated gene (UVRAG), mRNA. /FEA=mRNA /GEN=UVRAG /PROD=UV radiation resistance associated gene /DB_XREF=gi:4507860 /UG=Hs.13137 UV radiation resistance associated gene /FL=gb:NM_003369.1 gb:AB012958.1" NM_003369 UV radiation resistance associated UVRAG 7405 NM_003369 /// XM_005274209 /// XM_006718673 /// XM_006718674 /// XM_006718675 0006281 // DNA repair // traceable author statement /// 0010508 // positive regulation of autophagy // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 203242_s_at BG054550 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG054550 /FEA=EST /DB_XREF=gi:12511559 /DB_XREF=est:7o46a11.x1 /CLONE=IMAGE:3576885 /UG=Hs.154103 LIM protein (similar to rat protein kinase C-binding enigma) /FL=gb:AF061258.1 gb:NM_006457.1 BG054550 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203243_s_at NM_006457 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006457.1 /DEF=Homo sapiens LIM protein (similar to rat protein kinase C-binding enigma) (LIM), mRNA. /FEA=mRNA /GEN=LIM /PROD=LIM protein (similar to rat protein kinaseC-binding enigma) /DB_XREF=gi:5453713 /UG=Hs.154103 LIM protein (similar to rat protein kinase C-binding enigma) /FL=gb:AF061258.1 gb:NM_006457.1" NM_006457 PDZ and LIM domain 5 PDLIM5 10611 NM_001011513 /// NM_001011515 /// NM_001011516 /// NM_001256425 /// NM_001256426 /// NM_001256427 /// NM_001256428 /// NM_001256429 /// NM_006457 /// NR_046186 /// XM_005262693 /// XM_005262695 /// XM_005262696 /// XM_005262698 /// XM_006714066 /// XM_006714067 /// XM_006714068 /// XM_006714069 /// XM_006714070 0051963 // regulation of synapse assembly // inferred from sequence or structural similarity /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042805 // actinin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203244_at NM_000319 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000319.1 /DEF=Homo sapiens peroxisome receptor 1 (PXR1), mRNA. /FEA=mRNA /GEN=PXR1 /PROD=peroxisome receptor 1 /DB_XREF=gi:4506346 /UG=Hs.158084 peroxisome receptor 1 /FL=gb:NM_000319.1 gb:U19721.1" NM_000319 peroxisomal biogenesis factor 5 PEX5 5830 NM_000319 /// NM_001131023 /// NM_001131024 /// NM_001131025 /// NM_001131026 /// XM_005253451 /// XM_005253452 /// XM_005253453 /// XM_005253455 /// XM_006719129 /// XM_006719130 /// XM_006719131 /// XM_006719132 "0000038 // very long-chain fatty acid metabolic process // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from direct assay /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007006 // mitochondrial membrane organization // inferred from electronic annotation /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from genetic interaction /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0016558 // protein import into peroxisome matrix // non-traceable author statement /// 0016560 // protein import into peroxisome matrix, docking // inferred from direct assay /// 0016561 // protein import into peroxisome matrix, translocation // inferred from direct assay /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0048468 // cell development // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 1901094 // negative regulation of protein homotetramerization // inferred from direct assay" 0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000268 // peroxisome targeting sequence binding // inferred from direct assay /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from direct assay /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from mutant phenotype /// 0005052 // peroxisome matrix targeting signal-1 binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 203245_s_at BC002791 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002791.1 /DEF=Homo sapiens, homologous to yeast nitrogen permease (candidate tumor suppressor), clone MGC:3527, mRNA, complete cds. /FEA=mRNA /PROD=homologous to yeast nitrogen permease (candidatetumor suppressor) /DB_XREF=gi:12803888 /UG=Hs.169780 homologous to yeast nitrogen permease (candidate tumor suppressor) /FL=gb:BC002791.1 gb:AF040707.1 gb:NM_006545.1" BC002791 long intergenic non-protein coding RNA 94 LINC00094 266655 NR_002800 /// NR_015427 203246_s_at NM_006545 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006545.1 /DEF=Homo sapiens homologous to yeast nitrogen permease (candidate tumor suppressor) (NPR2L), mRNA. /FEA=mRNA /GEN=NPR2L /PROD=homologous to yeast nitrogen permease (candidatetumor suppressor) /DB_XREF=gi:5729948 /UG=Hs.169780 homologous to yeast nitrogen permease (candidate tumor suppressor) /FL=gb:BC002791.1 gb:AF040707.1 gb:NM_006545.1" NM_006545 nitrogen permease regulator-like 2 (S. cerevisiae) NPRL2 10641 NM_006545 /// XM_005264806 /// XM_005264808 /// XM_006712937 0006468 // protein phosphorylation // inferred from direct assay /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0004672 // protein kinase activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203247_s_at BC003566 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003566.1 /DEF=Homo sapiens, zinc finger protein 24 (KOX 17), clone MGC:2057, mRNA, complete cds. /FEA=mRNA /PROD=zinc finger protein 24 (KOX 17) /DB_XREF=gi:13097725 /UG=Hs.183593 zinc finger protein 24 (KOX 17) /FL=gb:BC003566.1 gb:U68536.1 gb:AF038964.1 gb:NM_006965.1" BC003566 zinc finger protein 24 ZNF24 7572 NM_006965 /// XM_005258341 /// XM_005258342 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203248_at NM_006965 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006965.1 /DEF=Homo sapiens zinc finger protein 24 (KOX 17) (ZNF24), mRNA. /FEA=mRNA /GEN=ZNF24 /PROD=zinc finger protein 24 (KOX 17) /DB_XREF=gi:5902161 /UG=Hs.183593 zinc finger protein 24 (KOX 17) /FL=gb:BC003566.1 gb:U68536.1 gb:AF038964.1 gb:NM_006965.1" NM_006965 zinc finger protein 24 ZNF24 7572 NM_006965 /// XM_005258341 /// XM_005258342 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0042552 // myelination // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203249_at AB002386 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB002386.1 /DEF=Human mRNA for KIAA0388 gene, complete cds. /FEA=mRNA /GEN=KIAA0388 /DB_XREF=gi:2224716 /UG=Hs.194669 enhancer of zeste (Drosophila) homolog 1 /FL=gb:U50315.1 gb:AB002386.1 gb:NM_001991.1" AB002386 enhancer of zeste 1 polycomb repressive complex 2 subunit EZH1 2145 NM_001991 /// XM_005257144 /// XM_005257145 /// XM_005257146 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0046976 // histone methyltransferase activity (H3-K27 specific) // inferred from electronic annotation 203250_at NM_014892 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014892.1 /DEF=Homo sapiens KIAA1116 protein (KIAA1116), mRNA. /FEA=mRNA /GEN=KIAA1116 /PROD=KIAA1116 protein /DB_XREF=gi:7662491 /UG=Hs.227602 KIAA1116 protein /FL=gb:AB029039.1 gb:NM_014892.1" NM_014892 SR-related CTD-associated factor 8 SCAF8 22828 NM_001286188 /// NM_001286189 /// NM_001286194 /// NM_001286199 /// NM_014892 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0016363 // nuclear matrix // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0043175 // RNA polymerase core enzyme binding // inferred from physical interaction 203252_at NM_005851 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005851.1 /DEF=Homo sapiens tumor suppressor deleted in oral cancer-related 1 (DOC-1R), mRNA. /FEA=mRNA /GEN=DOC-1R /PROD=tumor suppressor deleted in oral cancer-related1 /DB_XREF=gi:5031668 /UG=Hs.25664 tumor suppressor deleted in oral cancer-related 1 /FL=gb:BC002850.1 gb:AF089814.1 gb:NM_005851.1" NM_005851 cyclin-dependent kinase 2 associated protein 2 CDK2AP2 10263 NM_001271849 /// NM_005851 /// NR_073484 0016310 // phosphorylation // inferred from electronic annotation 0016301 // kinase activity // inferred from electronic annotation 203253_s_at NM_015216 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015216.1 /DEF=Homo sapiens KIAA0433 protein (KIAA0433), mRNA. /FEA=mRNA /GEN=KIAA0433 /PROD=KIAA0433 protein /DB_XREF=gi:7662117 /UG=Hs.26179 KIAA0433 protein /FL=gb:NM_015216.1" NM_015216 diphosphoinositol pentakisphosphate kinase 2 PPIP5K2 23262 NM_001276277 /// NM_001281471 /// NM_015216 /// NR_074081 /// XM_005271935 /// XM_005271936 /// XM_005271938 /// XM_005277534 /// XM_005277535 /// XM_005277536 /// XM_005277538 /// XM_005277539 /// XM_005277541 /// XM_006714576 /// XM_006714577 /// XM_006714578 0006020 // inositol metabolic process // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0000827 // inositol-1,3,4,5,6-pentakisphosphate kinase activity // inferred from sequence or structural similarity /// 0000832 // inositol hexakisphosphate 5-kinase activity // inferred from sequence or structural similarity /// 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033857 // diphosphoinositol-pentakisphosphate kinase activity // inferred from sequence or structural similarity /// 0052723 // inositol hexakisphosphate 1-kinase activity // inferred from electronic annotation /// 0052724 // inositol hexakisphosphate 3-kinase activity // inferred from electronic annotation" 203254_s_at NM_006289 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006289.1 /DEF=Homo sapiens talin (TLN), mRNA. /FEA=mRNA /GEN=TLN /PROD=talin /DB_XREF=gi:5454129 /UG=Hs.278559 talin /FL=gb:AF078828.1 gb:NM_006289.1 gb:AF177198.1" NM_006289 talin 1 TLN1 7094 NM_006289 /// XM_005251564 /// XM_006716852 0002576 // platelet degranulation // traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007043 // cell-cell junction assembly // traceable author statement /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0001726 // ruffle // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred by curator /// 0005925 // focal adhesion // inferred from direct assay /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0005925 // focal adhesion // non-traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from physical interaction /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017166 // vinculin binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation 203255_at NM_018693 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018693.1 /DEF=Homo sapiens vitiligo-associated protein VIT-1 (VIT1), mRNA. /FEA=mRNA /GEN=VIT1 /PROD=vitiligo-associated protein VIT-1 /DB_XREF=gi:10048403 /UG=Hs.284289 vitiligo-associated protein VIT-1 /FL=gb:NM_018693.1 gb:AF264714.1" NM_018693 F-box protein 11 FBXO11 80204 NM_001190274 /// NM_012167 /// NM_018693 /// NM_025133 /// XM_005264572 /// XM_005264573 /// XM_005264574 0006464 // cellular protein modification process // inferred from direct assay /// 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement /// 0035246 // peptidyl-arginine N-methylation // inferred from direct assay 0000151 // ubiquitin ligase complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016274 // protein-arginine N-methyltransferase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203256_at NM_001793 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001793.1 /DEF=Homo sapiens cadherin 3, type 1, P-cadherin (placental) (CDH3), mRNA. /FEA=mRNA /GEN=CDH3 /PROD=cadherin 3, type 1, P-cadherin (placental) /DB_XREF=gi:4502722 /UG=Hs.2877 cadherin 3, type 1, P-cadherin (placental) /FL=gb:NM_001793.1" NM_001793 "cadherin 3, type 1, P-cadherin (placental)" CDH3 1001 NM_001793 0001895 // retina homeostasis // inferred from mutant phenotype /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010838 // positive regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022405 // hair cycle process // inferred from mutant phenotype /// 0031424 // keratinization // inferred from mutant phenotype /// 0032773 // positive regulation of monophenol monooxygenase activity // inferred from mutant phenotype /// 0032912 // negative regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0048023 // positive regulation of melanin biosynthetic process // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051796 // negative regulation of catagen // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060901 // regulation of hair cycle by canonical Wnt signaling pathway // inferred from mutant phenotype /// 1902910 // positive regulation of melanosome transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203257_s_at NM_024113 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024113.1 /DEF=Homo sapiens hypothetical protein MGC4707 (MGC4707), mRNA. /FEA=mRNA /GEN=MGC4707 /PROD=hypothetical protein MGC4707 /DB_XREF=gi:13129129 /UG=Hs.291003 hypothetical protein MGC4707 /FL=gb:BC001860.1 gb:NM_024113.1" NM_024113 chromosome 11 open reading frame 49 C11orf49 79096 NM_001003676 /// NM_001003677 /// NM_001003678 /// NM_001278222 /// NM_024113 /// NR_103471 /// NR_103472 /// XM_006718315 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 203258_at NM_006442 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006442.1 /DEF=Homo sapiens DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1), mRNA. /FEA=mRNA /GEN=DRAP1 /PROD=DR1-associated protein 1 (negative cofactor 2alpha) /DB_XREF=gi:5453635 /UG=Hs.295362 DR1-associated protein 1 (negative cofactor 2 alpha) /FL=gb:U41843.1 gb:NM_006442.1" NM_006442 DR1-associated protein 1 (negative cofactor 2 alpha) DRAP1 10589 NM_006442 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203259_s_at BC001671 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001671.1 /DEF=Homo sapiens, Similar to CGI-130 protein, clone MGC:2442, mRNA, complete cds. /FEA=mRNA /PROD=Similar to CGI-130 protein /DB_XREF=gi:12804520 /UG=Hs.32826 CGI-130 protein /FL=gb:BC001671.1 gb:AF151888.1 gb:NM_016063.1" BC001671 HD domain containing 2 HDDC2 51020 NM_016063 /// XR_245538 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203260_at NM_016063 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016063.1 /DEF=Homo sapiens CGI-130 protein (LOC51020), mRNA. /FEA=mRNA /GEN=LOC51020 /PROD=CGI-130 protein /DB_XREF=gi:7705623 /UG=Hs.32826 CGI-130 protein /FL=gb:BC001671.1 gb:AF151888.1 gb:NM_016063.1" NM_016063 HD domain containing 2 HDDC2 51020 NM_016063 /// XR_245538 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203261_at NM_006571 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006571.1 /DEF=Homo sapiens novel RGD-containing protein (WS-3), mRNA. /FEA=mRNA /GEN=WS-3 /PROD=novel RGD-containing protein /DB_XREF=gi:5730115 /UG=Hs.39913 novel RGD-containing protein /FL=gb:D84145.1 gb:NM_006571.1" NM_006571 dynactin 6 DCTN6 10671 NM_006571 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from electronic annotation" 0045502 // dynein binding // inferred from electronic annotation 203262_s_at NM_004699 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004699.1 /DEF=Homo sapiens DNA segment on chromosome X (unique) 9928 expressed sequence (DXS9928E), mRNA. /FEA=mRNA /GEN=DXS9928E /PROD=XAP-5 protein /DB_XREF=gi:4758219 /UG=Hs.54277 DNA segment on chromosome X (unique) 9928 expressed sequence /FL=gb:BC000028.1 gb:D83260.1 gb:AD001530.1 gb:NM_004699.1" NM_004699 "family with sequence similarity 50, member A" FAM50A 9130 NM_004699 0007283 // spermatogenesis // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement 0044822 // poly(A) RNA binding // inferred from direct assay 203263_s_at AI625739 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI625739 /FEA=EST /DB_XREF=gi:4650670 /DB_XREF=est:ty65g05.x1 /CLONE=IMAGE:2283992 /UG=Hs.54697 Cdc42 guanine exchange factor (GEF) 9 /FL=gb:NM_015185.1 AI625739 Cdc42 guanine nucleotide exchange factor (GEF) 9 ARHGEF9 23229 NM_001173479 /// NM_001173480 /// NM_015185 /// XM_005262249 /// XM_005262250 /// XM_005262251 /// XM_005262252 /// XM_005262253 /// XM_006724636 /// XM_006724637 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203264_s_at NM_015185 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015185.1 /DEF=Homo sapiens Cdc42 guanine exchange factor (GEF) 9 (ARHGEF9), mRNA. /FEA=mRNA /GEN=ARHGEF9 /PROD=Cdc42 guanine exchange factor (GEF) 9 /DB_XREF=gi:7662107 /UG=Hs.54697 Cdc42 guanine exchange factor (GEF) 9 /FL=gb:NM_015185.1" NM_015185 Cdc42 guanine nucleotide exchange factor (GEF) 9 ARHGEF9 23229 NM_001173479 /// NM_001173480 /// NM_015185 /// XM_005262249 /// XM_005262250 /// XM_005262251 /// XM_005262252 /// XM_005262253 /// XM_006724636 /// XM_006724637 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203265_s_at AA810268 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA810268 /FEA=EST /DB_XREF=gi:2879627 /DB_XREF=est:od14f07.s1 /CLONE=IMAGE:1367941 /UG=Hs.75217 mitogen-activated protein kinase kinase 4 /FL=gb:NM_003010.1 gb:L36870.1 gb:U17743.1 AA810268 mitogen-activated protein kinase kinase 4 MAP2K4 6416 NM_001281435 /// NM_003010 /// XM_005256753 /// XM_005256755 /// XM_006721568 0000165 // MAPK cascade // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation" 203266_s_at NM_003010 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003010.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), mRNA. /FEA=mRNA /GEN=MAP2K4 /PROD=mitogen-activated protein kinase kinase 4 /DB_XREF=gi:4506888 /UG=Hs.75217 mitogen-activated protein kinase kinase 4 /FL=gb:NM_003010.1 gb:L36870.1 gb:U17743.1" NM_003010 mitogen-activated protein kinase kinase 4 MAP2K4 6416 NM_001281435 /// NM_003010 /// XM_005256753 /// XM_005256755 /// XM_006721568 0000165 // MAPK cascade // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0007257 // activation of JUN kinase activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0072709 // cellular response to sorbitol // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0032839 // dendrite cytoplasm // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008545 // JUN kinase kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from electronic annotation" 203267_s_at BF223206 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF223206 /FEA=EST /DB_XREF=gi:11130383 /DB_XREF=est:7q30e06.x1 /CLONE=IMAGE:3699923 /UG=Hs.78582 developmentally regulated GTP-binding protein 2 /FL=gb:BC000493.1 gb:NM_001388.1 BF223206 developmentally regulated GTP binding protein 2 DRG2 1819 NM_001388 /// XM_005256499 /// XM_005256500 /// XM_006721468 0007165 // signal transduction // traceable author statement /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation 203268_s_at NM_001388 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001388.1 /DEF=Homo sapiens developmentally regulated GTP-binding protein 2 (DRG2), mRNA. /FEA=mRNA /GEN=DRG2 /PROD=developmentally regulated GTP-binding protein 2 /DB_XREF=gi:4557536 /UG=Hs.78582 developmentally regulated GTP-binding protein 2 /FL=gb:BC000493.1 gb:NM_001388.1" NM_001388 developmentally regulated GTP binding protein 2 DRG2 1819 NM_001388 /// XM_005256499 /// XM_005256500 /// XM_006721468 0007165 // signal transduction // traceable author statement /// 0015684 // ferrous iron transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation 203269_at NM_003580 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003580.1 /DEF=Homo sapiens neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF), mRNA. /FEA=mRNA /GEN=NSMAF /PROD=neutral sphingomyelinase (N-SMase) activationassociated factor /DB_XREF=gi:4505464 /UG=Hs.78687 neutral sphingomyelinase (N-SMase) activation associated factor /FL=gb:NM_003580.1" NM_003580 neutral sphingomyelinase (N-SMase) activation associated factor NSMAF 8439 NM_001144772 /// NM_003580 0006672 // ceramide metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016230 // sphingomyelin phosphodiesterase activator activity // inferred from electronic annotation 203270_at NM_012145 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012145.1 /DEF=Homo sapiens deoxythymidylate kinase (thymidylate kinase) (DTYMK), mRNA. /FEA=mRNA /GEN=DTYMK /PROD=deoxythymidylate kinase (thymidylate kinase) /DB_XREF=gi:6912339 /UG=Hs.79006 deoxythymidylate kinase (thymidylate kinase) /FL=gb:BC001827.1 gb:L16991.1 gb:NM_012145.1" NM_012145 deoxythymidylate kinase (thymidylate kinase) DTYMK 1841 NM_001165031 /// NM_012145 /// NR_033255 0006233 // dTDP biosynthetic process // inferred from electronic annotation /// 0006235 // dTTP biosynthetic process // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement /// 0046940 // nucleoside monophosphate phosphorylation // not recorded /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0004798 // thymidylate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0050145 // nucleoside phosphate kinase activity // not recorded 203271_s_at NM_005148 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005148.1 /DEF=Homo sapiens unc119 (C.elegans) homolog (UNC119), mRNA. /FEA=mRNA /GEN=UNC119 /PROD=unc119 (C.elegans) homolog /DB_XREF=gi:4827047 /UG=Hs.81728 unc119 (C.elegans) homolog /FL=gb:U40998.1 gb:AF028788.1 gb:NM_005148.1" NM_005148 unc-119 homolog (C. elegans) UNC119 9094 NM_005148 /// NM_054035 "0006810 // transport // inferred from electronic annotation /// 0007109 // cytokinesis, completion of separation // inferred from mutant phenotype /// 0007268 // synaptic transmission // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0042953 // lipoprotein transport // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from mutant phenotype /// 1900186 // negative regulation of clathrin-mediated endocytosis // inferred from sequence or structural similarity /// 2001287 // negative regulation of caveolin-mediated endocytosis // inferred from sequence or structural similarity" 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay /// 0051233 // spindle midzone // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay 203272_s_at BF308548 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF308548 /FEA=EST /DB_XREF=gi:11255776 /DB_XREF=est:601890403F1 /CLONE=IMAGE:4131457 /UG=Hs.8186 lung cancer candidate /FL=gb:AF055479.1 gb:NM_007275.1 BF308548 tumor suppressor candidate 2 TUSC2 11334 NM_007275 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032618 // interleukin-15 production // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0071609 // chemokine (C-C motif) ligand 5 production // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 203273_s_at NM_007275 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007275.1 /DEF=Homo sapiens lung cancer candidate (FUS1), mRNA. /FEA=mRNA /GEN=FUS1 /PROD=lung cancer candidate /DB_XREF=gi:6005759 /UG=Hs.8186 lung cancer candidate /FL=gb:AF055479.1 gb:NM_007275.1" NM_007275 tumor suppressor candidate 2 TUSC2 11334 NM_007275 0001779 // natural killer cell differentiation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0032618 // interleukin-15 production // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from electronic annotation /// 0071609 // chemokine (C-C motif) ligand 5 production // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 203274_at NM_012151 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012151.2 /DEF=Homo sapiens coagulation factor VIII-associated (intronic transcript) (F8A), mRNA. /FEA=mRNA /GEN=F8A /PROD=coagulation factor VIII-associated protein /DB_XREF=gi:12056462 /UG=Hs.83363 coagulation factor VIII-associated (intronic transcript) /FL=gb:NM_012151.2" NM_012151 coagulation factor VIII-associated 1 /// coagulation factor VIII-associated 2 /// coagulation factor VIII-associated 3 F8A1 /// F8A2 /// F8A3 8263 /// 474383 /// 474384 NM_001007523 /// NM_001007524 /// NM_012151 0005634 // nucleus // inferred from direct assay 203275_at NM_002199 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002199.2 /DEF=Homo sapiens interferon regulatory factor 2 (IRF2), mRNA. /FEA=mRNA /GEN=IRF2 /PROD=interferon regulatory factor 2 /DB_XREF=gi:4755144 /UG=Hs.83795 interferon regulatory factor 2 /FL=gb:NM_002199.2" NM_002199 interferon regulatory factor 2 IRF2 3660 NM_002199 /// XM_005262984 /// XM_005262986 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from direct assay 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 203276_at NM_005573 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005573.1 /DEF=Homo sapiens lamin B1 (LMNB1), mRNA. /FEA=mRNA /GEN=LMNB1 /PROD=lamin B1 /DB_XREF=gi:5031876 /UG=Hs.89497 lamin B1 /FL=gb:M34458.1 gb:NM_005573.1" NM_005573 lamin B1 LMNB1 4001 NM_001198557 /// NM_005573 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005638 // lamin filament // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation 203277_at NM_004401 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004401.1 /DEF=Homo sapiens DNA fragmentation factor, 45 kD, alpha polypeptide (DFFA), mRNA. /FEA=mRNA /GEN=DFFA /PROD=DNA fragmentation factor, 45 kD, alphapolypeptide /DB_XREF=gi:4758147 /UG=Hs.105658 DNA fragmentation factor, 45 kD, alpha polypeptide /FL=gb:BC000037.1 gb:U91985.1 gb:NM_004401.1" NM_004401 "DNA fragmentation factor, 45kDa, alpha polypeptide" DFFA 1676 NM_004401 /// NM_213566 0006309 // apoptotic DNA fragmentation // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 1900118 // negative regulation of execution phase of apoptosis // inferred from direct assay /// 1902511 // negative regulation of apoptotic DNA fragmentation // inferred from direct assay 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005811 // lipid particle // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004536 // deoxyribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203278_s_at NM_016621 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016621.1 /DEF=Homo sapiens hypothetical protein (LOC51317), mRNA. /FEA=mRNA /GEN=LOC51317 /PROD=hypothetical protein /DB_XREF=gi:7706159 /UG=Hs.106826 KIAA1696 protein /FL=gb:AF208848.1 gb:NM_016621.1" NM_016621 PHD finger protein 21A PHF21A 51317 NM_001101802 /// NM_016621 /// XM_005252962 /// XM_005252963 /// XM_005252964 /// XM_005252965 /// XM_005252967 /// XM_005252970 /// XM_006718247 /// XM_006718248 /// XR_242810 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001967 // suckling behavior // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation" 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203279_at NM_014674 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014674.1 /DEF=Homo sapiens KIAA0212 gene product (KIAA0212), mRNA. /FEA=mRNA /GEN=KIAA0212 /PROD=KIAA0212 gene product /DB_XREF=gi:7662001 /UG=Hs.154332 KIAA0212 gene product /FL=gb:D86967.1 gb:NM_014674.1" NM_014674 "ER degradation enhancer, mannosidase alpha-like 1" EDEM1 9695 NM_014674 /// XM_006713424 /// XM_006713425 /// XR_245168 0006457 // protein folding // traceable author statement /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from sequence or structural similarity "0004571 // mannosyl-oligosaccharide 1,2-alpha-mannosidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0051787 // misfolded protein binding // inferred from direct assay" 203280_at NM_014649 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014649.1 /DEF=Homo sapiens KIAA0138 gene product (KIAA0138), mRNA. /FEA=mRNA /GEN=KIAA0138 /PROD=KIAA0138 gene product /DB_XREF=gi:7661935 /UG=Hs.159384 KIAA0138 gene product /FL=gb:D50928.1 gb:NM_014649.1" NM_014649 scaffold attachment factor B2 SAFB2 9667 NM_014649 /// XM_005259688 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203281_s_at NM_003335 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003335.1 /DEF=Homo sapiens ubiquitin-activating enzyme E1-like (UBE1L), mRNA. /FEA=mRNA /GEN=UBE1L /PROD=ubiquitin-activating enzyme E1-like /DB_XREF=gi:4507766 /UG=Hs.16695 ubiquitin-activating enzyme E1-like /FL=gb:NM_003335.1 gb:L13852.1" NM_003335 microRNA 5193 /// ubiquitin-like modifier activating enzyme 7 MIR5193 /// UBA7 7318 /// 100847079 NM_003335 /// NR_049825 /// XM_005265430 /// XM_006713321 0006464 // cellular protein modification process // inferred from direct assay /// 0016567 // protein ubiquitination // not recorded /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019941 // modification-dependent protein catabolic process // not recorded /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005634 // nucleus // not recorded /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004839 // ubiquitin activating enzyme activity // not recorded /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019782 // ISG15 activating enzyme activity // inferred from direct assay 203282_at NM_000158 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000158.1 /DEF=Homo sapiens glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) (GBE1), mRNA. /FEA=mRNA /GEN=GBE1 /PROD=glucan (1,4-alpha-), branching enzyme 1(glycogen branching enzyme) /DB_XREF=gi:4557618 /UG=Hs.1691 glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) /FL=gb:L07956.1 gb:NM_000158.1" NM_000158 "glucan (1,4-alpha-), branching enzyme 1" GBE1 2632 NM_000158 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0003844 // 1,4-alpha-glucan branching enzyme activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0043169 // cation binding // inferred from electronic annotation" 203283_s_at AK023260 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK023260.1 /DEF=Homo sapiens cDNA FLJ13198 fis, clone NT2RP3004454, highly similar to Homo sapiens mRNA for KIAA0448 protein. /FEA=mRNA /DB_XREF=gi:10435114 /UG=Hs.169939 heparan sulfate 2-O-sulfotransferase /FL=gb:NM_012262.2 gb:AB007917.1 gb:AB024568.1" AK023260 heparan sulfate 2-O-sulfotransferase 1 HS2ST1 9653 NM_001134492 /// NM_012262 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203284_s_at AW151887 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW151887 /FEA=EST /DB_XREF=gi:6199872 /DB_XREF=est:xf72c12.x1 /CLONE=IMAGE:2623606 /UG=Hs.169939 heparan sulfate 2-O-sulfotransferase /FL=gb:NM_012262.2 gb:AB007917.1 gb:AB024568.1 AW151887 heparan sulfate 2-O-sulfotransferase 1 HS2ST1 9653 NM_001134492 /// NM_012262 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203285_s_at NM_012262 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012262.2 /DEF=Homo sapiens heparan sulfate 2-O-sulfotransferase (HS2ST1), mRNA. /FEA=mRNA /GEN=HS2ST1 /PROD=heparan sulfate 2-O-sulfotransferase 1 /DB_XREF=gi:12545388 /UG=Hs.169939 heparan sulfate 2-O-sulfotransferase /FL=gb:NM_012262.2 gb:AB007917.1 gb:AB024568.1" NM_012262 heparan sulfate 2-O-sulfotransferase 1 HS2ST1 9653 NM_001134492 /// NM_012262 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203286_at NM_014901 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014901.1 /DEF=Homo sapiens KIAA1100 protein (KIAA1100), mRNA. /FEA=mRNA /GEN=KIAA1100 /PROD=KIAA1100 protein /DB_XREF=gi:7662485 /UG=Hs.179946 KIAA1100 protein /FL=gb:AB029023.1 gb:NM_014901.1" NM_014901 ring finger protein 44 RNF44 22838 NM_014901 /// XM_005265840 /// XM_005265841 /// XM_005265842 /// XM_005265843 /// XM_005265844 /// XM_005265845 /// XM_006714831 /// XM_006714832 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203287_at NM_005558 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005558.1 /DEF=Homo sapiens ladinin 1 (LAD1), mRNA. /FEA=mRNA /GEN=LAD1 /PROD=ladinin 1 /DB_XREF=gi:5031844 /UG=Hs.18141 ladinin 1 /FL=gb:U42408.1 gb:NM_005558.1" NM_005558 ladinin 1 LAD1 3898 NM_005558 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay 0005198 // structural molecule activity // traceable author statement 203288_at NM_014686 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014686.1 /DEF=Homo sapiens KIAA0355 gene product (KIAA0355), mRNA. /FEA=mRNA /GEN=KIAA0355 /PROD=KIAA0355 gene product /DB_XREF=gi:7662075 /UG=Hs.186840 KIAA0355 gene product /FL=gb:AB002353.1 gb:NM_014686.1" NM_014686 KIAA0355 KIAA0355 9710 NM_014686 /// XM_005259444 203289_s_at BE791629 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE791629 /FEA=EST /DB_XREF=gi:10212827 /DB_XREF=est:601585959F1 /CLONE=IMAGE:3940215 /UG=Hs.19699 Conserved gene telomeric to alpha globin cluster /FL=gb:NM_012075.1 BE791629 nitrogen permease regulator-like 3 (S. cerevisiae) NPRL3 8131 NM_001039476 /// NM_001077350 /// NM_001243247 /// NM_001243248 /// NM_001243249 /// NM_012075 0003281 // ventricular septum development // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation 203290_at NM_002122 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002122.1 /DEF=Homo sapiens major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1), mRNA. /FEA=mRNA /GEN=HLA-DQA1 /PROD=major histocompatibility complex, class II, DQalpha 1 /DB_XREF=gi:4504406 /UG=Hs.198253 major histocompatibility complex, class II, DQ alpha 1 /FL=gb:M33906.1 gb:M17846.1 gb:M17847.1 gb:M26041.1 gb:M16995.1 gb:NM_002122.1" NM_002122 "major histocompatibility complex, class II, DQ alpha 1" HLA-DQA1 3117 NM_002122 /// XM_003846468 /// XM_005274953 /// XM_005275108 /// XM_005275333 /// XM_005275542 /// XM_005275544 /// XM_006715079 /// XM_006725484 /// XM_006725999 0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from sequence or structural similarity /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0032395 // MHC class II receptor activity // traceable author statement /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 203291_at NM_013316 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013316.1 /DEF=Homo sapiens CCR4-NOT transcription complex, subunit 4 (CNOT4), mRNA. /FEA=mRNA /GEN=CNOT4 /PROD=CCR4-NOT transcription complex, subunit 4 /DB_XREF=gi:7019466 /UG=Hs.20423 CCR4-NOT transcription complex, subunit 4 /FL=gb:U71267.1 gb:NM_013316.1" NM_013316 "CCR4-NOT transcription complex, subunit 4" CNOT4 4850 NM_001008225 /// NM_001190847 /// NM_001190848 /// NM_001190849 /// NM_001190850 /// NM_013316 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0030014 // CCR4-NOT complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203292_s_at NM_021729 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021729.2 /DEF=Homo sapiens vacuolar protein sorting 11 (yeast homolog) (VPS11), mRNA. /FEA=mRNA /GEN=VPS11 /PROD=vacuolar protein sorting 11 (yeast homolog) /DB_XREF=gi:11141864 /UG=Hs.234282 vacuolar protein sorting 11 (yeast homolog) /FL=gb:AB027508.2 gb:NM_021729.2 gb:AF308800.1" NM_021729 vacuolar protein sorting 11 homolog (S. cerevisiae) VPS11 55823 NM_001290185 /// NM_021729 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005884 // actin filament // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030897 // HOPS complex // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203293_s_at NM_005570 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005570.2 /DEF=Homo sapiens lectin, mannose-binding, 1 (LMAN1), mRNA. /FEA=mRNA /GEN=LMAN1 /PROD=lectin, mannose-binding, 1 precursor /DB_XREF=gi:10862689 /UG=Hs.287912 lectin, mannose-binding, 1 /FL=gb:NM_005570.2 gb:U09716.1" NM_005570 "lectin, mannose-binding, 1" LMAN1 3998 NM_005570 0006457 // protein folding // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0032527 // protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 203294_s_at U09716 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U09716.1 /DEF=Human mannose-specific lectin (MR60) mRNA, complete cds. /FEA=mRNA /GEN=MR60 /PROD=mannose-specific lectin /DB_XREF=gi:606827 /UG=Hs.287912 lectin, mannose-binding, 1 /FL=gb:NM_005570.2 gb:U09716.1" U09716 "lectin, mannose-binding, 1" LMAN1 3998 NM_005570 0006457 // protein folding // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0007029 // endoplasmic reticulum organization // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from mutant phenotype /// 0007596 // blood coagulation // traceable author statement /// 0010638 // positive regulation of organelle organization // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0032527 // protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 0034498 // early endosome to Golgi transport // inferred from mutant phenotype /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 203295_s_at AW440492 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW440492 /FEA=EST /DB_XREF=gi:6975798 /DB_XREF=est:hb91c10.x1 /CLONE=IMAGE:2890578 /UG=Hs.34114 ATPase, Na+K+ transporting, alpha 2 (+) polypeptide /FL=gb:NM_000702.1" AW440492 "ATPase, Na+/K+ transporting, alpha 2 polypeptide" ATP1A2 477 NM_000702 0001504 // neurotransmitter uptake // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0006814 // sodium ion transport // non-traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0006942 // regulation of striated muscle contraction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0040011 // locomotion // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045988 // negative regulation of striated muscle contraction // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203296_s_at NM_000702 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000702.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, alpha 2 (+) polypeptide (ATP1A2), mRNA. /FEA=mRNA /GEN=ATP1A2 /PROD=ATPase, Na+K+ transporting, alpha 2 (+)polypeptide /DB_XREF=gi:4502270 /UG=Hs.34114 ATPase, Na+K+ transporting, alpha 2 (+) polypeptide /FL=gb:NM_000702.1" NM_000702 "ATPase, Na+/K+ transporting, alpha 2 polypeptide" ATP1A2 477 NM_000702 0001504 // neurotransmitter uptake // inferred from electronic annotation /// 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from electronic annotation /// 0006813 // potassium ion transport // non-traceable author statement /// 0006814 // sodium ion transport // non-traceable author statement /// 0006937 // regulation of muscle contraction // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // inferred from electronic annotation /// 0006942 // regulation of striated muscle contraction // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0015672 // monovalent inorganic cation transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from mutant phenotype /// 0040011 // locomotion // inferred from electronic annotation /// 0045822 // negative regulation of heart contraction // inferred from electronic annotation /// 0045988 // negative regulation of striated muscle contraction // inferred from electronic annotation /// 0051481 // negative regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0015077 // monovalent inorganic cation transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0019829 // cation-transporting ATPase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203297_s_at BG029530 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG029530 /FEA=EST /DB_XREF=gi:12418626 /DB_XREF=est:602297090F1 /CLONE=IMAGE:4391375 /UG=Hs.40154 jumonji (mouse) homolog /FL=gb:NM_004973.2 gb:U57592.1 BG029530 "jumonji, AT rich interactive domain 2" JARID2 3720 NM_001267040 /// NM_004973 /// XM_005249089 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from sequence or structural similarity" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from sequence or structural similarity /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0032452 // histone demethylase activity // inferred from sequence or structural similarity 203298_s_at NM_004973 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004973.2 /DEF=Homo sapiens jumonji (mouse) homolog (JMJ), mRNA. /FEA=mRNA /GEN=JMJ /PROD=jumonji /DB_XREF=gi:11863151 /UG=Hs.40154 jumonji (mouse) homolog /FL=gb:NM_004973.2 gb:U57592.1" NM_004973 "jumonji, AT rich interactive domain 2" JARID2 3720 NM_001267040 /// NM_004973 /// XM_005249089 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031061 // negative regulation of histone methylation // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from sequence or structural similarity" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from sequence or structural similarity /// 0035098 // ESC/E(Z) complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0032452 // histone demethylase activity // inferred from sequence or structural similarity 203299_s_at AF251295 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF251295.1 /DEF=Homo sapiens DC22 mRNA, complete cds. /FEA=mRNA /PROD=DC22 /DB_XREF=gi:12005731 /UG=Hs.40368 adaptor-related protein complex 1, sigma 2 subunit /FL=gb:AF251295.1 gb:BC001117.1 gb:AB015320.1 gb:NM_003916.1" AF251295 "adaptor-related protein complex 1, sigma 2 subunit" AP1S2 8905 NM_001272071 /// NM_003916 /// XM_005274612 /// XM_005274614 /// XR_247289 /// XR_247290 /// XR_247291 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement 0008565 // protein transporter activity // inferred from electronic annotation 203300_x_at NM_003916 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003916.1 /DEF=Homo sapiens adaptor-related protein complex 1, sigma 2 subunit (AP1S2), mRNA. /FEA=mRNA /GEN=AP1S2 /PROD=adaptor-related protein complex 1, sigma 2subunit /DB_XREF=gi:4506956 /UG=Hs.40368 adaptor-related protein complex 1, sigma 2 subunit /FL=gb:AF251295.1 gb:BC001117.1 gb:AB015320.1 gb:NM_003916.1" NM_003916 "adaptor-related protein complex 1, sigma 2 subunit" AP1S2 8905 NM_001272071 /// NM_003916 /// XM_005274612 /// XM_005274614 /// XR_247289 /// XR_247290 /// XR_247291 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement 0008565 // protein transporter activity // inferred from electronic annotation 203301_s_at NM_021145 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021145.1 /DEF=Homo sapiens cyclin D binding Myb-like transcription factor 1 (DMTF), mRNA. /FEA=mRNA /GEN=DMTF /PROD=cyclin D binding Myb-like transcription factor1 /DB_XREF=gi:10863946 /UG=Hs.5671 cyclin D binding Myb-like transcription factor 1 /FL=gb:NM_021145.1 gb:AF084530.1" NM_021145 cyclin D binding myb-like transcription factor 1 DMTF1 9988 NM_001142326 /// NM_001142327 /// NM_021145 /// NR_024549 /// NR_024550 /// XM_005250734 /// XM_006716197 /// XM_006716198 /// XM_006716199 /// XM_006716200 /// XM_006716201 /// XM_006716202 /// XM_006716203 /// XM_006716204 /// XM_006716205 /// XM_006716206 /// XR_428190 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement 203302_at NM_000788 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000788.1 /DEF=Homo sapiens deoxycytidine kinase (DCK), mRNA. /FEA=mRNA /GEN=DCK /PROD=deoxycytidine kinase /DB_XREF=gi:4503268 /UG=Hs.709 deoxycytidine kinase /FL=gb:M60527.1 gb:NM_000788.1" NM_000788 deoxycytidine kinase DCK 1633 NM_000788 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded /// 0042803 // protein homodimerization activity // inferred from physical interaction" 203303_at NM_006520 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006520.1 /DEF=Homo sapiens t-complex-associated-testis-expressed 1-like (TCTE1L), mRNA. /FEA=mRNA /GEN=TCTE1L /PROD=t-complex-associated-testis-expressed 1-like /DB_XREF=gi:5730086 /UG=Hs.75307 t-complex-associated-testis-expressed 1-like /FL=gb:BC000968.2 gb:U02556.1 gb:NM_006520.1" NM_006520 "dynein, light chain, Tctex-type 3" DYNLT3 6990 NM_006520 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation" 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203304_at NM_012342 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012342.1 /DEF=Homo sapiens putative transmembrane protein (NMA), mRNA. /FEA=mRNA /GEN=NMA /PROD=putative transmembrane protein /DB_XREF=gi:6912533 /UG=Hs.78776 putative transmembrane protein /FL=gb:U23070.1 gb:NM_012342.1" NM_012342 BMP and activin membrane-bound inhibitor BAMBI 25805 NM_012342 "0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from mutant phenotype /// 0016477 // cell migration // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032092 // positive regulation of protein binding // inferred from mutant phenotype /// 0035413 // positive regulation of catenin import into nucleus // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay" 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005114 // type II transforming growth factor beta receptor binding // traceable author statement 203305_at NM_000129 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000129.2 /DEF=Homo sapiens coagulation factor XIII, A1 polypeptide (F13A1), mRNA. /FEA=mRNA /GEN=F13A1 /PROD=coagulation factor XIII A1 subunit precursor /DB_XREF=gi:9961355 /UG=Hs.80424 coagulation factor XIII, A1 polypeptide /FL=gb:M14354.1 gb:NM_000129.2" NM_000129 "coagulation factor XIII, A1 polypeptide" F13A1 2162 NM_000129 /// XM_006715010 0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay "0003810 // protein-glutamine gamma-glutamyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203306_s_at NM_006416 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006416.1 /DEF=Homo sapiens solute carrier family 35 (CMP-sialic acid transporter), member 1 (SLC35A1), mRNA. /FEA=mRNA /GEN=SLC35A1 /PROD=solute carrier family 35 (CMP-sialic acidtransporter), member 1 /DB_XREF=gi:5453620 /UG=Hs.82921 solute carrier family 35 (CMP-sialic acid transporter), member 1 /FL=gb:D87969.1 gb:NM_006416.1" NM_006416 "solute carrier family 35 (CMP-sialic acid transporter), member A1" SLC35A1 10559 NM_001168398 /// NM_006416 0005975 // carbohydrate metabolic process // traceable author statement /// 0006464 // cellular protein modification process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015780 // nucleotide-sugar transport // inferred from electronic annotation /// 0015782 // CMP-N-acetylneuraminate transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 1901679 // nucleotide transmembrane transport // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005338 // nucleotide-sugar transmembrane transporter activity // inferred from electronic annotation /// 0005351 // sugar:proton symporter activity // inferred from electronic annotation /// 0005456 // CMP-N-acetylneuraminate transmembrane transporter activity // traceable author statement 203307_at NM_005275 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005275.1 /DEF=Homo sapiens guanine nucleotide binding protein-like 1 (GNL1), mRNA. /FEA=mRNA /GEN=GNL1 /PROD=guanine nucleotide binding protein-like 1 /DB_XREF=gi:4885288 /UG=Hs.83147 guanine nucleotide binding protein-like 1 /FL=gb:NM_005275.1 gb:L25665.1" NM_005275 guanine nucleotide binding protein-like 1 GNL1 2794 NM_005275 /// XM_005249015 /// XM_005272793 /// XM_005274939 /// XM_005275093 /// XM_005275235 /// XM_005275369 /// XM_005275529 0002456 // T cell mediated immunity // non-traceable author statement /// 0006184 // GTP catabolic process // not recorded /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0042254 // ribosome biogenesis // not recorded 0005615 // extracellular space // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0005198 // structural molecule activity // non-traceable author statement /// 0005525 // GTP binding // non-traceable author statement 203308_x_at AI185798 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI185798 /FEA=EST /DB_XREF=gi:3736436 /DB_XREF=est:qe49f04.x1 /CLONE=IMAGE:1742335 /UG=Hs.83951 Hermansky-Pudlak syndrome /FL=gb:U65676.1 gb:NM_000195.1 AI185798 Hermansky-Pudlak syndrome 1 HPS1 3257 NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 /// XM_005269755 /// XM_005269756 /// XM_005269757 /// XM_005269758 /// XM_005269759 /// XM_005269760 /// XM_005269761 /// XM_006717818 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048069 // eye pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0031085 // BLOC-3 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 203309_s_at NM_000195 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000195.1 /DEF=Homo sapiens Hermansky-Pudlak syndrome (HPS), mRNA. /FEA=mRNA /GEN=HPS /PROD=Hermansky-Pudlak syndrome protein /DB_XREF=gi:4504484 /UG=Hs.83951 Hermansky-Pudlak syndrome /FL=gb:U65676.1 gb:NM_000195.1" NM_000195 Hermansky-Pudlak syndrome 1 HPS1 3257 NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 /// XM_005269755 /// XM_005269756 /// XM_005269757 /// XM_005269758 /// XM_005269759 /// XM_005269760 /// XM_005269761 /// XM_006717818 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048069 // eye pigmentation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005764 // lysosome // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0031085 // BLOC-3 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from physical interaction 203310_at NM_007269 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007269.1 /DEF=Homo sapiens syntaxin binding protein 3 (STXBP3), mRNA. /FEA=mRNA /GEN=STXBP3 /PROD=syntaxin 4 binding protein /DB_XREF=gi:6005885 /UG=Hs.8813 syntaxin binding protein 3 /FL=gb:D63506.1 gb:AF032922.1 gb:NM_007269.1" NM_007269 syntaxin binding protein 3 STXBP3 6814 NM_007269 0006810 // transport // inferred from electronic annotation /// 0006904 // vesicle docking involved in exocytosis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043312 // neutrophil degranulation // inferred from expression pattern /// 0045955 // negative regulation of calcium ion-dependent exocytosis // inferred from mutant phenotype /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0070527 // platelet aggregation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031091 // platelet alpha granule // inferred from direct assay /// 0042581 // specific granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070820 // tertiary granule // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from physical interaction 203311_s_at M57763 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M57763.1 /DEF=Human ADP-ribosylation factor (hARF6) mRNA, complete cds. /FEA=mRNA /GEN=hARF6 /PROD=ADP-ribosylation factor /DB_XREF=gi:178988 /UG=Hs.89474 ADP-ribosylation factor 6 /FL=gb:BC002952.1 gb:M57763.1 gb:NM_001663.2" M57763 ADP-ribosylation factor 6 ARF6 382 NM_001663 0001889 // liver development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0031529 // ruffle organization // inferred from direct assay /// 0033028 // myeloid cell apoptotic process // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0048261 // negative regulation of receptor-mediated endocytosis // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction 203312_x_at NM_001663 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001663.2 /DEF=Homo sapiens ADP-ribosylation factor 6 (ARF6), mRNA. /FEA=mRNA /GEN=ARF6 /PROD=ADP-ribosylation factor 6 /DB_XREF=gi:6996000 /UG=Hs.89474 ADP-ribosylation factor 6 /FL=gb:BC002952.1 gb:M57763.1 gb:NM_001663.2" NM_001663 ADP-ribosylation factor 6 ARF6 382 NM_001663 0001889 // liver development // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0030866 // cortical actin cytoskeleton organization // inferred from mutant phenotype /// 0031529 // ruffle organization // inferred from direct assay /// 0033028 // myeloid cell apoptotic process // inferred from electronic annotation /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0035020 // regulation of Rac protein signal transduction // inferred from direct assay /// 0036010 // protein localization to endosome // inferred from mutant phenotype /// 0048261 // negative regulation of receptor-mediated endocytosis // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051489 // regulation of filopodium assembly // inferred from direct assay /// 0060998 // regulation of dendritic spine development // inferred from sequence or structural similarity /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from sequence or structural similarity /// 0090162 // establishment of epithelial cell polarity // inferred from electronic annotation /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation 0001726 // ruffle // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // traceable author statement /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030139 // endocytic vesicle // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // inferred from electronic annotation /// 0031996 // thioesterase binding // inferred from physical interaction 203313_s_at NM_003244 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003244.1 /DEF=Homo sapiens TG-interacting factor (TALE family homeobox) (TGIF), mRNA. /FEA=mRNA /GEN=TGIF /PROD=TG-interacting factor (TALE family homeobox) /DB_XREF=gi:4507472 /UG=Hs.90077 TG-interacting factor (TALE family homeobox) /FL=gb:BC000814.1 gb:NM_003244.1 gb:AF179900.1" NM_003244 TGFB-induced factor homeobox 1 TGIF1 7050 NM_001278682 /// NM_001278684 /// NM_001278686 /// NM_003244 /// NM_170695 /// NM_173207 /// NM_173208 /// NM_173209 /// NM_173210 /// NM_173211 /// NM_174886 /// XM_005258135 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010470 // regulation of gastrulation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0038092 // nodal signaling pathway // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0070410 // co-SMAD binding // inferred from electronic annotation 203314_at NM_012227 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012227.1 /DEF=Homo sapiens Pseudoautosomal GTP-binding protein-like (PGPL), mRNA. /FEA=mRNA /GEN=PGPL /PROD=Pseudoautosomal GTP-binding protein-likeprotein /DB_XREF=gi:6912587 /UG=Hs.101033 Pseudoautosomal GTP-binding protein-like /FL=gb:NM_012227.1" NM_012227 GTP binding protein 6 (putative) GTPBP6 8225 NM_012227 /// XM_006724447 /// XM_006724868 0015684 // ferrous iron transport // inferred from electronic annotation 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0015093 // ferrous iron transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203315_at BC000103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000103.1 /DEF=Homo sapiens, NCK adaptor protein 2, clone MGC:1698, mRNA, complete cds. /FEA=mRNA /PROD=NCK adaptor protein 2 /DB_XREF=gi:12652708 /UG=Hs.101695 NCK adaptor protein 2 /FL=gb:BC000103.1 gb:AF043119.1 gb:AF047487.1 gb:NM_003581.1" BC000103 NCK adaptor protein 2 NCK2 8440 NM_001004720 /// NM_001004722 /// NM_003581 /// XM_006712797 /// XM_006712798 0006417 // regulation of translation // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // non-traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007176 // regulation of epidermal growth factor-activated receptor activity // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030838 // positive regulation of actin filament polymerization // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0042110 // T cell activation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012506 // vesicle membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0019887 // protein kinase regulator activity // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 203316_s_at NM_003094 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003094.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide E (SNRPE), mRNA. /FEA=mRNA /GEN=SNRPE /PROD=small nuclear ribonucleoprotein polypeptide E /DB_XREF=gi:4507128 /UG=Hs.1066 small nuclear ribonucleoprotein polypeptide E /FL=gb:BC002639.1 gb:M37716.1 gb:NM_003094.1" NM_003094 small nuclear ribonucleoprotein polypeptide E SNRPE 6635 NM_003094 "0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0042633 // hair cycle // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // non-traceable author statement /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // non-traceable author statement /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203317_at NM_012455 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012455.1 /DEF=Homo sapiens SEC7 homolog (TIC), mRNA. /FEA=mRNA /GEN=TIC /PROD=SEC7 homolog /DB_XREF=gi:6912705 /UG=Hs.110121 SEC7 homolog /FL=gb:U63127.1 gb:NM_012455.1" NM_012455 pleckstrin and Sec7 domain containing 4 PSD4 23550 NM_012455 /// XM_005263634 /// XM_006712392 /// XM_006712393 /// XM_006712394 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 203318_s_at NM_021964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021964.1 /DEF=Homo sapiens zinc finger protein 148 (pHZ-52) (ZNF148), mRNA. /FEA=mRNA /GEN=ZNF148 /PROD=zinc finger protein 148 (pHZ-52) /DB_XREF=gi:11415035 /UG=Hs.112180 zinc finger protein 148 (pHZ-52) /FL=gb:NM_021964.1 gb:L04282.1" NM_021964 zinc finger protein 148 ZNF148 7707 NM_021964 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007276 // gamete generation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203319_s_at L04282 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:L04282.1 /DEF=Human CACCC box-binding protein mRNA, complete cds. /FEA=mRNA /PROD=CACCC box-binding protein /DB_XREF=gi:388318 /UG=Hs.112180 zinc finger protein 148 (pHZ-52) /FL=gb:NM_021964.1 gb:L04282.1" L04282 zinc finger protein 148 ZNF148 7707 NM_021964 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007276 // gamete generation // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021762 // substantia nigra development // inferred from expression pattern /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0000976 // transcription regulatory region sequence-specific DNA binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203320_at NM_005475 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005475.1 /DEF=Homo sapiens lymphocyte adaptor protein (LNK), mRNA. /FEA=mRNA /GEN=LNK /PROD=lymphocyte adaptor protein /DB_XREF=gi:4885454 /UG=Hs.13131 lymphocyte adaptor protein /FL=gb:AF055581.1 gb:NM_005475.1" NM_005475 SH2B adaptor protein 3 SH2B3 10019 NM_001291424 /// NM_005475 /// XM_005253818 /// XM_005253819 /// XM_006719180 0007596 // blood coagulation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042301 // phosphate ion binding // inferred from electronic annotation 203321_s_at AK022688 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK022688.1 /DEF=Homo sapiens cDNA FLJ12626 fis, clone NT2RM4001810, weakly similar to AGGRECAN CORE PROTEIN PRECURSOR. /FEA=CDS /DB_XREF=gi:10434228 /UG=Hs.131915 KIAA0863 protein /FL=gb:AB020670.1 gb:NM_014913.1" AK022688 ADNP homeobox 2 ADNP2 22850 NM_014913 /// XM_005266656 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203322_at AU145934 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU145934 /FEA=EST /DB_XREF=gi:11007455 /DB_XREF=est:AU145934 /CLONE=HEMBA1006312 /UG=Hs.131915 KIAA0863 protein /FL=gb:AB020670.1 gb:NM_014913.1 AU145934 ADNP homeobox 2 ADNP2 22850 NM_014913 /// XM_005266656 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203323_at BF197655 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF197655 /FEA=EST /DB_XREF=gi:11086950 /DB_XREF=est:7m95b04.x1 /CLONE=IMAGE:3562710 /UG=Hs.139851 caveolin 2 /FL=gb:BC005256.1 gb:AF035752.1 gb:NM_001233.1 BF197655 caveolin 2 CAV2 858 NM_001206747 /// NM_001206748 /// NM_001233 /// NM_198212 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from direct assay /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from expression pattern /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from direct assay /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from mutant phenotype /// 0070836 // caveola assembly // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from electronic annotation 203324_s_at NM_001233 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001233.1 /DEF=Homo sapiens caveolin 2 (CAV2), mRNA. /FEA=mRNA /GEN=CAV2 /PROD=caveolin 2 /DB_XREF=gi:4557412 /UG=Hs.139851 caveolin 2 /FL=gb:BC005256.1 gb:AF035752.1 gb:NM_001233.1" NM_001233 caveolin 2 CAV2 858 NM_001206747 /// NM_001206748 /// NM_001233 /// NM_198212 0001937 // negative regulation of endothelial cell proliferation // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from direct assay /// 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007029 // endoplasmic reticulum organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from expression pattern /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016050 // vesicle organization // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from direct assay /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from mutant phenotype /// 0070836 // caveola assembly // inferred from mutant phenotype 0000139 // Golgi membrane // inferred from electronic annotation /// 0002080 // acrosomal membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from electronic annotation 203325_s_at AI130969 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI130969 /FEA=EST /DB_XREF=gi:3600985 /DB_XREF=est:qc15e01.x1 /CLONE=IMAGE:1709688 /UG=Hs.146428 collagen, type V, alpha 1 /FL=gb:M76729.1 gb:D90279.1 gb:NM_000093.1" AI130969 "collagen, type V, alpha 1" COL5A1 1289 NM_000093 /// NM_001278074 "0001568 // blood vessel development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0035989 // tendon development // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0045112 // integrin biosynthetic process // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0051128 // regulation of cellular component organization // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 203326_x_at M76729 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M76729.1 /DEF=Human pro-alpha-1 (V) collagen mRNA, complete cds. /FEA=mRNA /GEN=COL5A1 /PROD=pro-alpha-1 type V collagen /DB_XREF=gi:189519 /UG=Hs.146428 collagen, type V, alpha 1 /FL=gb:M76729.1 gb:D90279.1 gb:NM_000093.1" M76729 "0001568 // blood vessel development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007411 // axon guidance // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from mutant phenotype /// 0035989 // tendon development // inferred from electronic annotation /// 0043206 // extracellular fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from electronic annotation /// 0043588 // skin development // inferred from mutant phenotype /// 0045112 // integrin biosynthetic process // inferred from mutant phenotype /// 0048592 // eye morphogenesis // inferred from mutant phenotype /// 0051128 // regulation of cellular component organization // inferred from electronic annotation" 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005588 // collagen type V trimer // inferred from mutant phenotype /// 0005588 // collagen type V trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0043394 // proteoglycan binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 203327_at N22903 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N22903 /FEA=EST /DB_XREF=gi:1137053 /DB_XREF=est:yx66e04.s1 /CLONE=IMAGE:266718 /UG=Hs.1508 insulin-degrading enzyme /FL=gb:M21188.1 gb:NM_004969.1 N22903 insulin-degrading enzyme IDE 3416 NM_001165946 /// NM_004969 /// XM_005269766 /// XM_005269769 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // non-traceable author statement /// 0008340 // determination of adult lifespan // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010992 // ubiquitin homeostasis // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 1901142 // insulin metabolic process // inferred from direct assay /// 1901143 // insulin catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031626 // beta-endorphin binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from direct assay /// 0043559 // insulin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203328_x_at NM_004969 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004969.1 /DEF=Homo sapiens insulin-degrading enzyme (IDE), mRNA. /FEA=mRNA /GEN=IDE /PROD=insulysin /DB_XREF=gi:4826769 /UG=Hs.1508 insulin-degrading enzyme /FL=gb:M21188.1 gb:NM_004969.1" NM_004969 insulin-degrading enzyme IDE 3416 NM_001165946 /// NM_004969 /// XM_005269766 /// XM_005269769 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // non-traceable author statement /// 0008340 // determination of adult lifespan // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010992 // ubiquitin homeostasis // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from electronic annotation /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 1901142 // insulin metabolic process // inferred from direct assay /// 1901143 // insulin catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031597 // cytosolic proteasome complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001540 // beta-amyloid binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031626 // beta-endorphin binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from direct assay /// 0043559 // insulin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203329_at NM_002845 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002845.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, M (PTPRM), mRNA. /FEA=mRNA /GEN=PTPRM /PROD=protein tyrosine phosphatase, receptor type, mupolypeptide /DB_XREF=gi:4506318 /UG=Hs.154151 protein tyrosine phosphatase, receptor type, M /FL=gb:NM_002845.1" NM_002845 "protein tyrosine phosphatase, receptor type, M" PTPRM 5797 NM_001105244 /// NM_002845 /// XM_006722335 /// XM_006722336 /// XM_006722337 /// XM_006722338 /// XR_430046 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from mutant phenotype /// 0010842 // retina layer formation // inferred from mutant phenotype /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from direct assay /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0031290 // retinal ganglion cell axon guidance // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0045909 // positive regulation of vasodilation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay 203330_s_at NM_003164 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003164.1 /DEF=Homo sapiens syntaxin 5A (STX5A), mRNA. /FEA=mRNA /GEN=STX5A /PROD=syntaxin 5A /DB_XREF=gi:4507292 /UG=Hs.154546 syntaxin 5A /FL=gb:NM_003164.1 gb:U26648.1" NM_003164 syntaxin 5 STX5 6811 NM_001244666 /// NM_003164 "0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0006903 // vesicle targeting // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // inferred from direct assay /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // traceable author statement /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005484 // SNAP receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 203331_s_at U53470 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U53470.1 /DEF=Human signaling inositol polyphosphate phosphatase SHIP II mRNA, complete cds. /FEA=mRNA /PROD=signaling inositol polyphosphate phosphataseSHIP II /DB_XREF=gi:4097284 /UG=Hs.155939 inositol polyphosphate-5-phosphatase, 145kD /FL=gb:U50040.1 gb:U57650.1 gb:U84400.1 gb:U53470.1 gb:NM_005541.1" U53470 "inositol polyphosphate-5-phosphatase, 145kDa" INPP5D 3635 NM_001017915 /// NM_005541 0002376 // immune system process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045409 // negative regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045656 // negative regulation of monocyte differentiation // inferred from electronic annotation /// 0045659 // negative regulation of neutrophil differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from electronic annotation 203332_s_at NM_005541 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005541.1 /DEF=Homo sapiens inositol polyphosphate-5-phosphatase, 145kD (INPP5D), mRNA. /FEA=mRNA /GEN=INPP5D /PROD=inositol polyphosphate-5-phosphatase, 145kD /DB_XREF=gi:5031798 /UG=Hs.155939 inositol polyphosphate-5-phosphatase, 145kD /FL=gb:U50040.1 gb:U57650.1 gb:U84400.1 gb:U53470.1 gb:NM_005541.1" NM_005541 "inositol polyphosphate-5-phosphatase, 145kDa" INPP5D 3635 NM_001017915 /// NM_005541 0002376 // immune system process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045409 // negative regulation of interleukin-6 biosynthetic process // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045621 // positive regulation of lymphocyte differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045656 // negative regulation of monocyte differentiation // inferred from electronic annotation /// 0045659 // negative regulation of neutrophil differentiation // inferred from electronic annotation /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0050777 // negative regulation of immune response // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050869 // negative regulation of B cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0034594 // phosphatidylinositol trisphosphate phosphatase activity // inferred from electronic annotation /// 0051425 // PTB domain binding // inferred from electronic annotation 203333_at NM_014970 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014970.1 /DEF=Homo sapiens smg GDS-ASSOCIATED PROTEIN (SMAP), mRNA. /FEA=mRNA /GEN=SMAP /PROD=smg GDS-ASSOCIATED PROTEIN /DB_XREF=gi:7657592 /UG=Hs.171374 smg GDS-ASSOCIATED PROTEIN /FL=gb:U59919.1 gb:NM_014970.1" NM_014970 kinesin-associated protein 3 KIFAP3 22920 NM_001204514 /// NM_001204516 /// NM_001204517 /// NM_014970 /// XM_005244970 0006461 // protein complex assembly // traceable author statement /// 0007017 // microtubule-based process // inferred from sequence or structural similarity /// 0007018 // microtubule-based movement // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0046587 // positive regulation of calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0072383 // plus-end-directed vesicle transport along microtubule // traceable author statement 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016939 // kinesin II complex // inferred from direct assay /// 0016939 // kinesin II complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction 203334_at NM_004941 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004941.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 8 (RNA helicase) (DDX8), mRNA. /FEA=mRNA /GEN=DDX8 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 8 /DB_XREF=gi:4826689 /UG=Hs.171872 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 8 (RNA helicase) /FL=gb:D50487.1 gb:NM_004941.1" NM_004941 DEAH (Asp-Glu-Ala-His) box polypeptide 8 DHX8 1659 NM_004941 /// XM_005257113 /// XM_005257114 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // traceable author statement /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203335_at NM_006214 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006214.1 /DEF=Homo sapiens phytanoyl-CoA hydroxylase (Refsum disease) (PHYH), mRNA. /FEA=mRNA /GEN=PHYH /PROD=phytanoyl-CoA hydroxylase (Refsum disease) /DB_XREF=gi:5453883 /UG=Hs.172887 phytanoyl-CoA hydroxylase (Refsum disease) /FL=gb:AF023462.1 gb:AF112977.1 gb:NM_006214.1" NM_006214 phytanoyl-CoA 2-hydroxylase PHYH 5264 NM_001037537 /// NM_006214 /// XM_005252469 0001561 // fatty acid alpha-oxidation // inferred from direct assay /// 0001561 // fatty acid alpha-oxidation // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006720 // isoprenoid metabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0097089 // methyl-branched fatty acid metabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from direct assay /// 0048244 // phytanoyl-CoA dioxygenase activity // inferred from direct assay /// 0048244 // phytanoyl-CoA dioxygenase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 203336_s_at AL548363 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL548363 /FEA=EST /DB_XREF=gi:12883296 /DB_XREF=est:AL548363 /CLONE=CS0DI016YO13 (5 prime) /UG=Hs.173274 integrin cytoplasmic domain-associated protein 1 /FL=gb:AF012023.1 gb:NM_004763.1 AL548363 integrin beta 1 binding protein 1 ITGB1BP1 9270 NM_004763 /// NM_022334 /// XM_005246183 /// XM_005246184 /// XM_005246185 /// XM_005246186 /// XM_005246187 /// XM_005246188 /// XM_005246189 /// XM_006711903 "0001525 // angiogenesis // inferred from electronic annotation /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010764 // negative regulation of fibroblast migration // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from direct assay /// 0016477 // cell migration // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0033622 // integrin activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035148 // tube formation // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from direct assay /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from sequence or structural similarity" 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203337_x_at NM_004763 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004763.1 /DEF=Homo sapiens integrin cytoplasmic domain-associated protein 1 (ICAP-1A), transcript variant 1, mRNA. /FEA=mRNA /GEN=ICAP-1A /PROD=integrin cytoplasmic domain-associated protein1, isoform 1 /DB_XREF=gi:4758577 /UG=Hs.173274 integrin cytoplasmic domain-associated protein 1 /FL=gb:AF012023.1 gb:NM_004763.1" NM_004763 integrin beta 1 binding protein 1 ITGB1BP1 9270 NM_004763 /// NM_022334 /// XM_005246183 /// XM_005246184 /// XM_005246185 /// XM_005246186 /// XM_005246187 /// XM_005246188 /// XM_005246189 /// XM_006711903 "0001525 // angiogenesis // inferred from electronic annotation /// 0002043 // blood vessel endothelial cell proliferation involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from direct assay /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010764 // negative regulation of fibroblast migration // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from direct assay /// 0016477 // cell migration // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0033622 // integrin activation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0035148 // tube formation // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0043088 // regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from direct assay /// 0045747 // positive regulation of Notch signaling pathway // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050880 // regulation of blood vessel size // inferred from direct assay /// 0051451 // myoblast migration // inferred from sequence or structural similarity /// 0051496 // positive regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090051 // negative regulation of cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 0090315 // negative regulation of protein targeting to membrane // inferred from direct assay /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from sequence or structural similarity" 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0030027 // lamellipodium // inferred from direct assay /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203338_at NM_006246 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006246.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (PPP2R5E), mRNA. /FEA=mRNA /GEN=PPP2R5E /PROD=protein phosphatase 2, regulatory subunit B(B56), epsilon isoform /DB_XREF=gi:5453955 /UG=Hs.173328 protein phosphatase 2, regulatory subunit B (B56), epsilon isoform /FL=gb:L76703.1 gb:NM_006246.1" NM_006246 "protein phosphatase 2, regulatory subunit B', epsilon isoform" PPP2R5E 5529 NM_001282179 /// NM_001282180 /// NM_001282181 /// NM_001282182 /// NM_006246 /// NR_104104 0007165 // signal transduction // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation 203339_at AI887457 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI887457 /FEA=EST /DB_XREF=gi:5592621 /DB_XREF=est:wm05f07.x1 /CLONE=IMAGE:2435077 /UG=Hs.179866 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 /FL=gb:NM_003705.1" AI887457 "solute carrier family 25 (aspartate/glutamate carrier), member 12" SLC25A12 8604 NM_003705 /// NR_047549 /// XM_005246923 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from direct assay /// 0015813 // L-glutamate transport // inferred from direct assay /// 0043490 // malate-aspartate shuttle // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0015183 // L-aspartate transmembrane transporter activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203340_s_at NM_003705 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003705.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier, Aralar), member 12 (SLC25A12), mRNA. /FEA=mRNA /GEN=SLC25A12 /PROD=solute carrier family 25 (mitochondrial carrier,Aralar), member 12 /DB_XREF=gi:4507006 /UG=Hs.179866 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 /FL=gb:NM_003705.1" NM_003705 "solute carrier family 25 (aspartate/glutamate carrier), member 12" SLC25A12 8604 NM_003705 /// NR_047549 /// XM_005246923 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015810 // aspartate transport // inferred from direct assay /// 0015813 // L-glutamate transport // inferred from direct assay /// 0043490 // malate-aspartate shuttle // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0015183 // L-aspartate transmembrane transporter activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203341_at NM_005760 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005760.1 /DEF=Homo sapiens CCAAT-box-binding transcription factor (CBF2), mRNA. /FEA=mRNA /GEN=CBF2 /PROD=CCAAT-box-binding transcription factor /DB_XREF=gi:5031624 /UG=Hs.184760 CCAAT-box-binding transcription factor /FL=gb:M37197.1 gb:NM_005760.1" NM_005760 "CCAAT/enhancer binding protein (C/EBP), zeta" CEBPZ 10153 NM_005760 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203342_at NM_005834 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005834.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 17 (yeast) homolog B (TIM17B), mRNA. /FEA=mRNA /GEN=TIM17B /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog B /DB_XREF=gi:5032180 /UG=Hs.19105 translocase of inner mitochondrial membrane 17 (yeast) homolog B /FL=gb:AJ005895.1 gb:AF034790.1 gb:AF077039.1 gb:NM_005834.1" NM_005834 translocase of inner mitochondrial membrane 17 homolog B (yeast) TIMM17B 10245 NM_001167947 /// NM_005834 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071806 // protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203343_at NM_003359 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003359.1 /DEF=Homo sapiens UDP-glucose dehydrogenase (UGDH), mRNA. /FEA=mRNA /GEN=UGDH /PROD=UDP-glucose dehydrogenase /DB_XREF=gi:4507812 /UG=Hs.28309 UDP-glucose dehydrogenase /FL=gb:AF061016.1 gb:NM_003359.1" NM_003359 UDP-glucose 6-dehydrogenase UGDH 7358 NM_001184700 /// NM_001184701 /// NM_003359 /// XM_005262667 /// XM_006714029 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006011 // UDP-glucose metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006065 // UDP-glucuronate biosynthetic process // inferred from electronic annotation /// 0006065 // UDP-glucuronate biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0052695 // cellular glucuronidation // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement "0003824 // catalytic activity // inferred from electronic annotation /// 0003979 // UDP-glucose 6-dehydrogenase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation" 203344_s_at NM_002894 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002894.1 /DEF=Homo sapiens retinoblastoma-binding protein 8 (RBBP8), mRNA. /FEA=mRNA /GEN=RBBP8 /PROD=retinoblastoma-binding protein 8 /DB_XREF=gi:4506440 /UG=Hs.29287 retinoblastoma-binding protein 8 /FL=gb:AF043431.1 gb:NM_002894.1" NM_002894 retinoblastoma binding protein 8 RBBP8 5932 NM_002894 /// NM_203291 /// NM_203292 /// XM_005258325 /// XM_005258326 /// XM_006722519 /// XM_006722520 /// XM_006722521 /// XM_006722522 "0000075 // cell cycle checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from mutant phenotype /// 0001835 // blastocyst hatching // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0010792 // DNA double-strand break processing involved in repair via single-strand annealing // inferred from mutant phenotype /// 0031572 // G2 DNA damage checkpoint // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from mutant phenotype /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203345_s_at AI566096 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI566096 /FEA=EST /DB_XREF=gi:4524548 /DB_XREF=est:tn53d02.x1 /CLONE=IMAGE:2172099 /UG=Hs.31016 putative DNA binding protein /FL=gb:AF072814.1 gb:NM_007358.1 AI566096 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203346_s_at AF072814 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF072814.1 /DEF=Homo sapiens PHD finger DNA binding protein isoform 1 (M96) mRNA, alternatively spliced, complete cds. /FEA=mRNA /GEN=M96 /PROD=PHD finger DNA binding protein isoform 1 /DB_XREF=gi:3342451 /UG=Hs.31016 putative DNA binding protein /FL=gb:AF072814.1 gb:NM_007358.1" AF072814 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203347_s_at NM_007358 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007358.1 /DEF=Homo sapiens putative DNA binding protein (M96), mRNA. /FEA=mRNA /GEN=M96 /PROD=putative DNA binding protein /DB_XREF=gi:6678763 /UG=Hs.31016 putative DNA binding protein /FL=gb:AF072814.1 gb:NM_007358.1" NM_007358 metal response element binding transcription factor 2 MTF2 22823 NM_001164391 /// NM_001164392 /// NM_001164393 /// NM_007358 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007379 // segment specification // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0061086 // negative regulation of histone H3-K27 methylation // inferred from sequence or structural similarity /// 0061087 // positive regulation of histone H3-K27 methylation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203348_s_at BF060791 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF060791 /FEA=EST /DB_XREF=gi:10819701 /DB_XREF=est:7j60g07.x1 /CLONE=IMAGE:3390876 /UG=Hs.43697 ets variant gene 5 (ets-related molecule) /FL=gb:NM_004454.1 BF060791 ets variant 5 ETV5 2119 NM_004454 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048133 // male germ-line stem cell division // inferred from electronic annotation /// 0050807 // regulation of synapse organization // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203349_s_at NM_004454 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004454.1 /DEF=Homo sapiens ets variant gene 5 (ets-related molecule) (ETV5), mRNA. /FEA=mRNA /GEN=ETV5 /PROD=ets variant gene 5 (ets-related molecule) /DB_XREF=gi:4758315 /UG=Hs.43697 ets variant gene 5 (ets-related molecule) /FL=gb:NM_004454.1" NM_004454 ets variant 5 ETV5 2119 NM_004454 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048133 // male germ-line stem cell division // inferred from electronic annotation /// 0050807 // regulation of synapse organization // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203350_at NM_001128 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001128.1 /DEF=Homo sapiens adaptor-related protein complex 1, gamma 1 subunit (AP1G1), mRNA. /FEA=mRNA /GEN=AP1G1 /PROD=adaptor-related protein complex 1, gamma 1subunit /DB_XREF=gi:4501978 /UG=Hs.5344 adaptor-related protein complex 1, gamma 1 subunit /FL=gb:AB015317.1 gb:NM_001128.1" NM_001128 "adaptor-related protein complex 1, gamma 1 subunit" AP1G1 164 NM_001030007 /// NM_001128 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016032 // viral process // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0032438 // melanosome organization // inferred by curator /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0043323 // positive regulation of natural killer cell degranulation // inferred from mutant phenotype /// 0045954 // positive regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0090160 // Golgi to lysosome transport // inferred from mutant phenotype 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0030665 // clathrin-coated vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from direct assay 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0019894 // kinesin binding // inferred from physical interaction /// 0030742 // GTP-dependent protein binding // inferred from physical interaction 203351_s_at AF047598 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF047598.1 /DEF=Homo sapiens origin recognition complex subunit 4 (ORC4L) mRNA, complete cds. /FEA=mRNA /GEN=ORC4L /PROD=origin recognition complex subunit 4 /DB_XREF=gi:2906225 /UG=Hs.55055 origin recognition complex, subunit 4 (yeast homolog)-like /FL=gb:BC005388.1 gb:AF022108.1 gb:AF047598.1 gb:NM_002552.1 gb:AF132596.1" AF047598 "origin recognition complex, subunit 4" ORC4 5000 NM_001190879 /// NM_001190881 /// NM_001190882 /// NM_002552 /// NM_181741 /// NM_181742 /// XM_006712556 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from mutant phenotype 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003688 // DNA replication origin binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 203352_at NM_002552 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002552.1 /DEF=Homo sapiens origin recognition complex, subunit 4 (yeast homolog)-like (ORC4L), mRNA. /FEA=mRNA /GEN=ORC4L /PROD=origin recognition complex, subunit 4 (yeasthomolog)-like /DB_XREF=gi:4505522 /UG=Hs.55055 origin recognition complex, subunit 4 (yeast homolog)-like /FL=gb:BC005388.1 gb:AF022108.1 gb:AF047598.1 gb:NM_002552.1 gb:AF132596.1" NM_002552 "origin recognition complex, subunit 4" ORC4 5000 NM_001190879 /// NM_001190881 /// NM_001190882 /// NM_002552 /// NM_181741 /// NM_181742 /// XM_006712556 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from mutant phenotype 0000808 // origin recognition complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from direct assay 0000166 // nucleotide binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003688 // DNA replication origin binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 203353_s_at NM_015846 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015846.1 /DEF=Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 1, mRNA. /FEA=mRNA /GEN=MBD1 /PROD=methyl-CpG binding domain protein 1, isoform 1 /DB_XREF=gi:7710138 /UG=Hs.6211 methyl-CpG binding domain protein 1 /FL=gb:AF078830.1 gb:NM_015846.1" NM_015846 methyl-CpG binding domain protein 1 MBD1 4152 NM_001204136 /// NM_001204137 /// NM_001204138 /// NM_001204139 /// NM_001204140 /// NM_001204141 /// NM_001204142 /// NM_001204143 /// NM_001204151 /// NM_002384 /// NM_015844 /// NM_015845 /// NM_015846 /// NM_015847 /// XM_005258262 /// XM_005258264 /// XM_005258265 /// XM_005258268 /// XM_005258271 /// XM_005258272 /// XM_005258274 /// XM_006722452 /// XM_006722453 /// XM_006722454 /// XM_006722455 /// XM_006722456 /// XM_006722457 /// XM_006722458 /// XM_006722459 /// XM_006722460 /// XM_006722461 /// XM_006722462 /// XM_006722463 /// XM_006722464 /// XM_006722465 /// XM_006722466 /// XM_006722467 /// XM_006722468 /// XM_006722469 /// XM_006722470 /// XM_006722471 /// XM_006722472 /// XM_006722473 /// XM_006722474 /// XM_006722475 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement" 0000785 // chromatin // inferred from electronic annotation /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008327 // methyl-CpG binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203354_s_at AW117368 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW117368 /FEA=EST /DB_XREF=gi:6085952 /DB_XREF=est:xd88h01.x1 /CLONE=IMAGE:2604721 /UG=Hs.6763 KIAA0942 protein /FL=gb:AF243495.2 gb:NM_015310.1 AW117368 pleckstrin and Sec7 domain containing 3 PSD3 23362 NM_015310 /// NM_206909 /// XM_005273461 /// XM_006716318 /// XM_006716319 /// XM_006716320 /// XM_006716321 /// XM_006716322 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation 203355_s_at NM_015310 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015310.1 /DEF=Homo sapiens KIAA0942 protein (KIAA0942), mRNA. /FEA=mRNA /GEN=KIAA0942 /PROD=KIAA0942 protein /DB_XREF=gi:7662395 /UG=Hs.6763 KIAA0942 protein /FL=gb:AF243495.2 gb:NM_015310.1" NM_015310 pleckstrin and Sec7 domain containing 3 PSD3 23362 NM_015310 /// NM_206909 /// XM_005273461 /// XM_006716318 /// XM_006716319 /// XM_006716320 /// XM_006716321 /// XM_006716322 0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation 203356_at BE349584 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE349584 /FEA=EST /DB_XREF=gi:9261437 /DB_XREF=est:ht55h12.x1 /CLONE=IMAGE:3150695 /UG=Hs.7145 calpain 7 /FL=gb:AB028639.1 gb:NM_014296.1 BE349584 calpain 7 CAPN7 23473 NM_014296 /// XM_005265008 /// XM_006713080 /// XR_245107 /// XR_245108 0006508 // proteolysis // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0097264 // self proteolysis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0090541 // MIT domain binding // inferred from physical interaction 203357_s_at NM_014296 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014296.1 /DEF=Homo sapiens calpain 7 (CAPN7), mRNA. /FEA=mRNA /GEN=CAPN7 /PROD=calpain 7 /DB_XREF=gi:7656958 /UG=Hs.7145 calpain 7 /FL=gb:AB028639.1 gb:NM_014296.1" NM_014296 calpain 7 CAPN7 23473 NM_014296 /// XM_005265008 /// XM_006713080 /// XR_245107 /// XR_245108 0006508 // proteolysis // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from direct assay /// 0097264 // self proteolysis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0090541 // MIT domain binding // inferred from physical interaction 203358_s_at NM_004456 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004456.1 /DEF=Homo sapiens enhancer of zeste (Drosophila) homolog 2 (EZH2), mRNA. /FEA=mRNA /GEN=EZH2 /PROD=enhancer of zeste (Drosophila) homolog 2 /DB_XREF=gi:4758323 /UG=Hs.77256 enhancer of zeste (Drosophila) homolog 2 /FL=gb:U61145.1 gb:NM_004456.1" NM_004456 enhancer of zeste 2 polycomb repressive complex 2 subunit EZH2 2146 NM_001203247 /// NM_001203248 /// NM_001203249 /// NM_004456 /// NM_152998 /// XM_005249962 /// XM_005249963 /// XM_005249964 /// XM_006715883 /// XM_006715884 /// XM_006715885 /// XM_006715886 /// XM_006715887 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0014013 // regulation of gliogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0034244 // negative regulation of transcription elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045605 // negative regulation of epidermal cell differentiation // inferred from electronic annotation /// 0045814 // negative regulation of gene expression, epigenetic // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0051154 // negative regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0070314 // G1 to G0 transition // inferred from electronic annotation /// 0070734 // histone H3-K27 methylation // inferred from direct assay /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0035098 // ESC/E(Z) complex // inferred from direct assay /// 0045120 // pronucleus // inferred from electronic annotation 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0001047 // core promoter binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0042054 // histone methyltransferase activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046976 // histone methyltransferase activity (H3-K27 specific) // traceable author statement 203359_s_at AL525412 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL525412 /FEA=EST /DB_XREF=gi:12788905 /DB_XREF=est:AL525412 /CLONE=CS0DC011YJ12 (5 prime) /UG=Hs.78221 c-myc binding protein /FL=gb:D50692.1 gb:AB007191.2 gb:NM_012333.2 AL525412 GJA9-MYCBP readthrough /// MYC binding protein GJA9-MYCBP /// MYCBP 26292 /// 100527950 NM_012333 /// NR_037632 /// NR_037633 /// NR_037634 /// NR_037635 /// NR_037636 /// NR_037637 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203360_s_at D50692 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D50692.1 /DEF=Homo sapiens mRNA for c-myc binding protein, complete cds. /FEA=mRNA /PROD=c-myc binding protein /DB_XREF=gi:1785850 /UG=Hs.78221 c-myc binding protein /FL=gb:D50692.1 gb:AB007191.2 gb:NM_012333.2" D50692 "gap junction protein, alpha 9, 59kDa /// GJA9-MYCBP readthrough /// MYC binding protein" GJA9 /// GJA9-MYCBP /// MYCBP 26292 /// 81025 /// 100527950 NM_012333 /// NM_030772 /// NR_037632 /// NR_037633 /// NR_037634 /// NR_037635 /// NR_037636 /// NR_037637 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203361_s_at NM_012333 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012333.2 /DEF=Homo sapiens c-myc binding protein (MYCBP), mRNA. /FEA=mRNA /GEN=MYCBP /PROD=c-myc binding protein /DB_XREF=gi:8850230 /UG=Hs.78221 c-myc binding protein /FL=gb:D50692.1 gb:AB007191.2 gb:NM_012333.2" NM_012333 GJA9-MYCBP readthrough /// MYC binding protein GJA9-MYCBP /// MYCBP 26292 /// 100527950 NM_012333 /// NR_037632 /// NR_037633 /// NR_037634 /// NR_037635 /// NR_037636 /// NR_037637 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007154 // cell communication // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from expression pattern" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203362_s_at NM_002358 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002358.2 /DEF=Homo sapiens MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 (MAD2L1), mRNA. /FEA=mRNA /GEN=MAD2L1 /PROD=MAD2-like 1 /DB_XREF=gi:6466452 /UG=Hs.79078 MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 /FL=gb:BC000356.1 gb:U65410.1 gb:NM_002358.2 gb:U31278.1" NM_002358 MAD2 mitotic arrest deficient-like 1 (yeast) MAD2L1 4085 NM_002358 0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0060564 // negative regulation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay" 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203363_s_at AU153525 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU153525 /FEA=EST /DB_XREF=gi:11015046 /DB_XREF=est:AU153525 /CLONE=NT2RP3003369 /UG=Hs.79672 KIAA0652 gene product /FL=gb:AB014552.1 gb:NM_014741.1 AU153525 autophagy related 13 ATG13 9776 NM_001142673 /// NM_001205119 /// NM_001205120 /// NM_001205121 /// NM_001205122 /// NM_014741 /// XM_005253262 /// XM_005253263 /// XM_005253265 /// XM_005253266 /// XM_005253268 /// XM_006718394 /// XM_006718395 /// XM_006718396 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0034273 // Atg1p signaling complex // /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 203364_s_at NM_014741 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014741.1 /DEF=Homo sapiens KIAA0652 gene product (KIAA0652), mRNA. /FEA=mRNA /GEN=KIAA0652 /PROD=KIAA0652 gene product /DB_XREF=gi:7662225 /UG=Hs.79672 KIAA0652 gene product /FL=gb:AB014552.1 gb:NM_014741.1" NM_014741 autophagy related 13 ATG13 9776 NM_001142673 /// NM_001205119 /// NM_001205120 /// NM_001205121 /// NM_001205122 /// NM_014741 /// XM_005253262 /// XM_005253263 /// XM_005253265 /// XM_005253266 /// XM_005253268 /// XM_006718394 /// XM_006718395 /// XM_006718396 0000045 // autophagic vacuole assembly // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation 0000407 // pre-autophagosomal structure // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0034273 // Atg1p signaling complex // /// 0070969 // ULK1-ATG13-FIP200 complex // inferred from physical interaction 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 203365_s_at NM_002428 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002428.1 /DEF=Homo sapiens matrix metalloproteinase 15 (membrane-inserted) (MMP15), mRNA. /FEA=mRNA /GEN=MMP15 /PROD=matrix metalloproteinase 15 preproprotein /DB_XREF=gi:4505210 /UG=Hs.80343 matrix metalloproteinase 15 (membrane-inserted) /FL=gb:D86331.1 gb:NM_002428.1" NM_002428 matrix metallopeptidase 15 (membrane-inserted) MMP15 4324 NM_002428 0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203366_at NM_002693 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002693.1 /DEF=Homo sapiens polymerase (DNA directed), gamma (POLG), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=POLG /PROD=polymerase (DNA directed), gamma /DB_XREF=gi:4505936 /UG=Hs.80961 polymerase (DNA directed), gamma /FL=gb:U60325.1 gb:D84103.1 gb:NM_002693.1" NM_002693 "polymerase (DNA directed), gamma" POLG 5428 NM_001126131 /// NM_002693 "0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005760 // gamma DNA polymerase complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 203367_at NM_007026 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007026.1 /DEF=Homo sapiens MKP-1 like protein tyrosine phosphatase (MKP-L), mRNA. /FEA=mRNA /GEN=MKP-L /PROD=MKP-1 like protein tyrosine phosphatase /DB_XREF=gi:5902001 /UG=Hs.91448 MKP-1 like protein tyrosine phosphatase /FL=gb:BC000370.1 gb:BC001894.1 gb:BC004448.1 gb:AF038844.1 gb:NM_007026.1 gb:AF120032.1" NM_007026 dual specificity phosphatase 14 DUSP14 11072 NM_007026 /// XM_005256977 /// XM_006725300 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // not recorded 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203368_at NM_015513 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015513.1 /DEF=Homo sapiens DKFZP566D213 protein (DKFZP566D213), mRNA. /FEA=mRNA /GEN=DKFZP566D213 /PROD=DKFZP566D213 protein /DB_XREF=gi:7661643 /UG=Hs.9383 DKFZP566D213 protein /FL=gb:AL050275.1 gb:NM_015513.1" NM_015513 cysteine-rich with EGF-like domains 1 CRELD1 78987 NM_001031717 /// NM_001077415 /// NM_015513 /// XM_006713328 /// XM_006713329 /// XM_006713330 /// XM_006713331 /// XR_427293 /// XR_427294 0003197 // endocardial cushion development // traceable author statement /// 0003279 // cardiac septum development // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203369_x_at AI825846 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI825846 /FEA=EST /DB_XREF=gi:5446517 /DB_XREF=est:td19c09.x1 /CLONE=IMAGE:2076112 /UG=Hs.102948 enigma (LIM domain protein) /FL=gb:NM_005451.2 gb:BC001093.1 gb:AF265209.1 AI825846 PDZ and LIM domain 7 (enigma) PDLIM7 9260 NM_005451 /// NM_203352 /// NM_203353 /// NM_213636 /// NR_103804 /// XM_006714937 /// XM_006714938 /// XM_006714939 /// XM_006714940 /// XM_006714941 0001503 // ossification // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203370_s_at NM_005451 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005451.2 /DEF=Homo sapiens enigma (LIM domain protein) (ENIGMA), mRNA. /FEA=mRNA /GEN=ENIGMA /PROD=enigma protein /DB_XREF=gi:11496884 /UG=Hs.102948 enigma (LIM domain protein) /FL=gb:NM_005451.2 gb:BC001093.1 gb:AF265209.1" NM_005451 PDZ and LIM domain 7 (enigma) PDLIM7 9260 NM_005451 /// NM_203352 /// NM_203353 /// NM_213636 /// NR_103804 /// XM_006714937 /// XM_006714938 /// XM_006714939 /// XM_006714940 /// XM_006714941 0001503 // ossification // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0001726 // ruffle // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203371_s_at NM_002491 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002491.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12) (NDUFB3), mRNA. /FEA=mRNA /GEN=NDUFB3 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 3 (12kD, B12) /DB_XREF=gi:4505360 /UG=Hs.109760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12) /FL=gb:AF047183.1 gb:NM_002491.1" NM_002491 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa" NDUFB3 4709 NM_001257102 /// NM_002491 /// XM_006712544 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022900 // electron transport chain // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203372_s_at AB004903 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB004903.1 /DEF=Homo sapiens mRNA for STAT induced STAT inhibitor-2, complete cds. /FEA=mRNA /PROD=STAT induced STAT inhibitor-2 /DB_XREF=gi:2443360 /UG=Hs.110776 STAT induced STAT inhibitor-2 /FL=gb:AB004903.1 gb:AB006966.1 gb:AF037989.1 gb:AF020590.1 gb:NM_003877.1" AB004903 suppressor of cytokine signaling 2 SOCS2 8835 NM_001270467 /// NM_001270468 /// NM_001270469 /// NM_001270470 /// NM_001270471 /// NM_003877 /// XM_005269213 /// XM_006719673 /// XM_006719674 0001558 // regulation of cell growth // non-traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046425 // regulation of JAK-STAT cascade // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005131 // growth hormone receptor binding // non-traceable author statement /// 0005148 // prolactin receptor binding // non-traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008269 // JAK pathway signal transduction adaptor activity // inferred from electronic annotation 203373_at NM_003877 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003877.1 /DEF=Homo sapiens STAT induced STAT inhibitor-2 (STATI2), mRNA. /FEA=mRNA /GEN=STATI2 /PROD=STAT induced STAT inhibitor-2 /DB_XREF=gi:4507262 /UG=Hs.110776 STAT induced STAT inhibitor-2 /FL=gb:AB004903.1 gb:AB006966.1 gb:AF037989.1 gb:AF020590.1 gb:NM_003877.1" NM_003877 suppressor of cytokine signaling 2 SOCS2 8835 NM_001270467 /// NM_001270468 /// NM_001270469 /// NM_001270470 /// NM_001270471 /// NM_003877 /// XM_005269213 /// XM_006719673 /// XM_006719674 0001558 // regulation of cell growth // non-traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009966 // regulation of signal transduction // non-traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032870 // cellular response to hormone stimulus // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046425 // regulation of JAK-STAT cascade // traceable author statement /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005131 // growth hormone receptor binding // non-traceable author statement /// 0005148 // prolactin receptor binding // non-traceable author statement /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008269 // JAK pathway signal transduction adaptor activity // inferred from electronic annotation 203374_s_at AW612376 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW612376 /FEA=EST /DB_XREF=gi:7317562 /DB_XREF=est:hg99b11.x1 /CLONE=IMAGE:2953725 /UG=Hs.1117 tripeptidyl peptidase II /FL=gb:M73047.1 gb:NM_003291.1 AW612376 tripeptidyl peptidase II TPP2 7174 NM_003291 /// XM_005254070 /// XM_005254071 /// XM_005254072 /// XM_005254073 /// XR_243046 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004175 // endopeptidase activity // traceable author statement /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008240 // tripeptidyl-peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 203375_s_at NM_003291 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003291.1 /DEF=Homo sapiens tripeptidyl peptidase II (TPP2), mRNA. /FEA=mRNA /GEN=TPP2 /PROD=tripeptidyl peptidase II /DB_XREF=gi:4507656 /UG=Hs.1117 tripeptidyl peptidase II /FL=gb:M73047.1 gb:NM_003291.1" NM_003291 tripeptidyl peptidase II TPP2 7174 NM_003291 /// XM_005254070 /// XM_005254071 /// XM_005254072 /// XM_005254073 /// XR_243046 0000209 // protein polyubiquitination // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006508 // proteolysis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0004175 // endopeptidase activity // traceable author statement /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008240 // tripeptidyl-peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 203376_at BG528818 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG528818 /FEA=EST /DB_XREF=gi:13520355 /DB_XREF=est:602579703F1 /CLONE=IMAGE:4713600 /UG=Hs.116674 pre-mRNA splicing factor 17 /FL=gb:AF038392.1 gb:AF061241.1 gb:NM_015891.1 BG528818 cell division cycle 40 CDC40 51362 NM_015891 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203377_s_at NM_015891 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015891.1 /DEF=Homo sapiens pre-mRNA splicing factor (PRP17), mRNA. /FEA=mRNA /GEN=PRP17 /PROD=pre-mRNA splicing factor /DB_XREF=gi:7706656 /UG=Hs.116674 pre-mRNA splicing factor 17 /FL=gb:AF038392.1 gb:AF061241.1 gb:NM_015891.1" NM_015891 cell division cycle 40 CDC40 51362 NM_015891 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // traceable author statement /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203378_at AB020631 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB020631.1 /DEF=Homo sapiens mRNA for KIAA0824 protein, partial cds. /FEA=mRNA /GEN=KIAA0824 /PROD=KIAA0824 protein /DB_XREF=gi:4240136 /UG=Hs.123654 PCF11p homolog /FL=gb:AF046935.1 gb:NM_015885.1" AB020631 PCF11 cleavage and polyadenylation factor subunit PCF11 51585 NM_015885 /// XM_005274048 /// XM_005274049 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006379 // mRNA cleavage // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005849 // mRNA cleavage factor complex // non-traceable author statement 203379_at NM_002953 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002953.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 90kD, polypeptide 1 (RPS6KA1), mRNA. /FEA=mRNA /GEN=RPS6KA1 /PROD=ribosomal protein S6 kinase, 90kD, polypeptide1 /DB_XREF=gi:4506732 /UG=Hs.149957 ribosomal protein S6 kinase, 90kD, polypeptide 1 /FL=gb:L07597.1 gb:NM_002953.1" NM_002953 "ribosomal protein S6 kinase, 90kDa, polypeptide 1" RPS6KA1 6195 NM_001006665 /// NM_002953 /// XM_005245966 /// XM_005245967 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043555 // regulation of translation in response to stress // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 2000491 // positive regulation of hepatic stellate cell activation // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203380_x_at NM_006925 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006925.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 5 (SFRS5), mRNA. /FEA=mRNA /GEN=SFRS5 /PROD=splicing factor, arginineserine-rich 5 /DB_XREF=gi:5902077 /UG=Hs.166975 splicing factor, arginineserine-rich 5 /FL=gb:U30827.1 gb:NM_006925.1" NM_006925 serine/arginine-rich splicing factor 5 SRSF5 6430 NM_001039465 /// NM_006925 /// XM_005267998 /// XM_005267999 /// XM_005268000 /// XM_005268001 /// XR_429326 /// XR_429327 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006406 // mRNA export from nucleus // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009611 // response to wounding // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // inferred from electronic annotation 203381_s_at N33009 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N33009 /FEA=EST /DB_XREF=gi:1153408 /DB_XREF=est:yy31f09.s1 /CLONE=IMAGE:272873 /UG=Hs.169401 apolipoprotein E /FL=gb:BC003557.1 gb:M12529.1 gb:K00396.1 gb:NM_000041.1 N33009 apolipoprotein E APOE 348 NM_000041 /// XM_005258867 "0000302 // response to reactive oxygen species // non-traceable author statement /// 0001523 // retinoid metabolic process // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from genetic interaction /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from direct assay /// 0017038 // protein import // inferred from direct assay /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030516 // regulation of axon extension // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032805 // positive regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034374 // low-density lipoprotein particle remodeling // inferred from electronic annotation /// 0034375 // high-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034382 // chylomicron remnant clearance // inferred from mutant phenotype /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from direct assay /// 0046907 // intracellular transport // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051055 // negative regulation of lipid biosynthetic process // inferred from direct assay /// 0051651 // maintenance of location in cell // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from direct assay /// 0061000 // negative regulation of dendritic spine development // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from direct assay /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901627 // negative regulation of postsynaptic membrane organization // inferred from direct assay /// 1901628 // positive regulation of postsynaptic membrane organization // inferred from direct assay /// 1901630 // negative regulation of presynaptic membrane organization // inferred from direct assay /// 1901631 // positive regulation of presynaptic membrane organization // inferred from direct assay /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902947 // regulation of tau-protein kinase activity // inferred from direct assay /// 1902951 // negative regulation of dendritic spine maintenance // inferred from direct assay /// 1902952 // positive regulation of dendritic spine maintenance // inferred from direct assay /// 1902995 // positive regulation of phospholipid efflux // inferred from direct assay /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from direct assay /// 1902999 // negative regulation of phospholipid efflux // inferred from direct assay /// 1903001 // negative regulation of lipid transport across blood brain barrier // inferred from direct assay /// 1903002 // positive regulation of lipid transport across blood brain barrier // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // non-traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0043025 // neuronal cell body // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008289 // lipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046848 // hydroxyapatite binding // inferred from electronic annotation /// 0046911 // metal chelating activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048156 // tau protein binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation 203382_s_at NM_000041 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000041.1 /DEF=Homo sapiens apolipoprotein E (APOE), mRNA. /FEA=mRNA /GEN=APOE /PROD=apolipoprotein E /DB_XREF=gi:4557324 /UG=Hs.169401 apolipoprotein E /FL=gb:BC003557.1 gb:M12529.1 gb:K00396.1 gb:NM_000041.1" NM_000041 apolipoprotein E APOE 348 NM_000041 /// XM_005258867 "0000302 // response to reactive oxygen species // non-traceable author statement /// 0001523 // retinoid metabolic process // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from genetic interaction /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from direct assay /// 0017038 // protein import // inferred from direct assay /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030516 // regulation of axon extension // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032805 // positive regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034374 // low-density lipoprotein particle remodeling // inferred from electronic annotation /// 0034375 // high-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034382 // chylomicron remnant clearance // inferred from mutant phenotype /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from direct assay /// 0046907 // intracellular transport // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051055 // negative regulation of lipid biosynthetic process // inferred from direct assay /// 0051651 // maintenance of location in cell // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from direct assay /// 0061000 // negative regulation of dendritic spine development // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from direct assay /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901627 // negative regulation of postsynaptic membrane organization // inferred from direct assay /// 1901628 // positive regulation of postsynaptic membrane organization // inferred from direct assay /// 1901630 // negative regulation of presynaptic membrane organization // inferred from direct assay /// 1901631 // positive regulation of presynaptic membrane organization // inferred from direct assay /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902947 // regulation of tau-protein kinase activity // inferred from direct assay /// 1902951 // negative regulation of dendritic spine maintenance // inferred from direct assay /// 1902952 // positive regulation of dendritic spine maintenance // inferred from direct assay /// 1902995 // positive regulation of phospholipid efflux // inferred from direct assay /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from direct assay /// 1902999 // negative regulation of phospholipid efflux // inferred from direct assay /// 1903001 // negative regulation of lipid transport across blood brain barrier // inferred from direct assay /// 1903002 // positive regulation of lipid transport across blood brain barrier // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // non-traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0043025 // neuronal cell body // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008289 // lipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046848 // hydroxyapatite binding // inferred from electronic annotation /// 0046911 // metal chelating activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048156 // tau protein binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation 203383_s_at BG111661 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG111661 /FEA=EST /DB_XREF=gi:12605167 /DB_XREF=est:602285419F1 /CLONE=IMAGE:4372612 /UG=Hs.172647 golgi autoantigen, golgin subfamily a, 1 /FL=gb:U51587.1 gb:NM_002077.1" BG111661 golgin A1 GOLGA1 2800 NM_002077 /// XM_005251929 /// XM_006717062 /// XM_006717063 0000042 // protein targeting to Golgi // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203384_s_at NM_002077 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002077.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 1 (GOLGA1), mRNA. /FEA=mRNA /GEN=GOLGA1 /PROD=golgin 97 /DB_XREF=gi:4504062 /UG=Hs.172647 golgi autoantigen, golgin subfamily a, 1 /FL=gb:U51587.1 gb:NM_002077.1" NM_002077 golgin A1 GOLGA1 2800 NM_002077 /// XM_005251929 /// XM_006717062 /// XM_006717063 0000042 // protein targeting to Golgi // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203385_at NM_001345 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001345.1 /DEF=Homo sapiens diacylglycerol kinase, alpha (80kD) (DGKA), mRNA. /FEA=mRNA /GEN=DGKA /PROD=diacylglycerol kinase, alpha (80kD) /DB_XREF=gi:11415023 /UG=Hs.172690 diacylglycerol kinase, alpha (80kD) /FL=gb:NM_001345.1 gb:AF064770.1" NM_001345 "diacylglycerol kinase, alpha 80kDa" DGKA 1606 NM_001345 /// NM_201444 /// NM_201445 /// NM_201554 /// XM_005268688 /// XM_005268689 /// XM_005268690 /// XM_006719260 /// XR_429084 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203386_at AI650848 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI650848 /FEA=EST /DB_XREF=gi:4734827 /DB_XREF=est:wa95d04.x1 /CLONE=IMAGE:2303911 /UG=Hs.173802 KIAA0603 gene product /FL=gb:AB011175.1 gb:NM_014832.1 AI650848 "TBC1 domain family, member 4" TBC1D4 9882 NM_001286658 /// NM_001286659 /// NM_014832 /// XM_005266603 /// XM_005266605 /// XM_006719902 /// XM_006719903 0016192 // vesicle-mediated transport // inferred from mutant phenotype /// 0031339 // negative regulation of vesicle fusion // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203387_s_at NM_014832 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014832.1 /DEF=Homo sapiens KIAA0603 gene product (KIAA0603), mRNA. /FEA=mRNA /GEN=KIAA0603 /PROD=KIAA0603 gene product /DB_XREF=gi:7662197 /UG=Hs.173802 KIAA0603 gene product /FL=gb:AB011175.1 gb:NM_014832.1" NM_014832 "TBC1 domain family, member 4" TBC1D4 9882 NM_001286658 /// NM_001286659 /// NM_014832 /// XM_005266603 /// XM_005266605 /// XM_006719902 /// XM_006719903 0016192 // vesicle-mediated transport // inferred from mutant phenotype /// 0031339 // negative regulation of vesicle fusion // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203388_at NM_004313 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004313.1 /DEF=Homo sapiens arrestin, beta 2 (ARRB2), mRNA. /FEA=mRNA /GEN=ARRB2 /PROD=arrestin beta 2 /DB_XREF=gi:4757779 /UG=Hs.18142 arrestin, beta 2 /FL=gb:AF106941.1 gb:NM_004313.1" NM_004313 "arrestin, beta 2" ARRB2 409 NM_001257328 /// NM_001257329 /// NM_001257330 /// NM_001257331 /// NM_004313 /// NM_199004 /// NR_047516 /// XM_006721520 /// XM_006721521 /// XR_429814 "0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0002031 // G-protein coupled receptor internalization // inferred from mutant phenotype /// 0002032 // desensitization of G-protein coupled receptor protein signaling pathway by arrestin // inferred from mutant phenotype /// 0002092 // positive regulation of receptor internalization // inferred from mutant phenotype /// 0006309 // apoptotic DNA fragmentation // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0031397 // negative regulation of protein ubiquitination // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from genetic interaction /// 0031623 // receptor internalization // inferred from direct assay /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032226 // positive regulation of synaptic transmission, dopaminergic // inferred from electronic annotation /// 0032691 // negative regulation of interleukin-1 beta production // inferred from electronic annotation /// 0032695 // negative regulation of interleukin-12 production // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0032720 // negative regulation of tumor necrosis factor production // inferred from electronic annotation /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from electronic annotation /// 0034260 // negative regulation of GTPase activity // inferred from electronic annotation /// 0034392 // negative regulation of smooth muscle cell apoptotic process // inferred from electronic annotation /// 0042699 // follicle-stimulating hormone signaling pathway // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045953 // negative regulation of natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051928 // positive regulation of calcium ion transport // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060765 // regulation of androgen receptor signaling pathway // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031691 // alpha-1A adrenergic receptor binding // inferred from electronic annotation /// 0031692 // alpha-1B adrenergic receptor binding // inferred from electronic annotation /// 0031701 // angiotensin receptor binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation /// 0031748 // D1 dopamine receptor binding // inferred from electronic annotation /// 0031762 // follicle-stimulating hormone receptor binding // inferred from electronic annotation /// 0031826 // type 2A serotonin receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // inferred from direct assay /// 0043422 // protein kinase B binding // inferred from electronic annotation /// 0051019 // mitogen-activated protein kinase binding // inferred from electronic annotation /// 0071889 // 14-3-3 protein binding // inferred from electronic annotation 203389_at AF035621 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF035621.1 /DEF=Homo sapiens kinesin-related protein (KIF3C) mRNA, complete cds. /FEA=mRNA /GEN=KIF3C /PROD=kinesin-related protein /DB_XREF=gi:2815621 /UG=Hs.21611 kinesin family member 3C /FL=gb:AF018164.1 gb:AF035621.1 gb:NM_002254.1" AF035621 kinesin family member 3C KIF3C 3797 NM_002254 /// XM_005264299 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203390_s_at NM_002254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002254.1 /DEF=Homo sapiens kinesin family member 3C (KIF3C), mRNA. /FEA=mRNA /GEN=KIF3C /PROD=kinesin family member 3C /DB_XREF=gi:4504868 /UG=Hs.21611 kinesin family member 3C /FL=gb:AF018164.1 gb:AF035621.1 gb:NM_002254.1" NM_002254 kinesin family member 3C KIF3C 3797 NM_002254 /// XM_005264299 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203391_at NM_004470 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004470.1 /DEF=Homo sapiens FK506-binding protein 2 (13kD) (FKBP2), mRNA. /FEA=mRNA /GEN=FKBP2 /PROD=FK506-binding protein 2 (13kD) /DB_XREF=gi:4758381 /UG=Hs.227729 FK506-binding protein 2 (13kD) /FL=gb:BC003384.1 gb:M65128.1 gb:M75099.1 gb:NM_004470.1" NM_004470 "FK506 binding protein 2, 13kDa" FKBP2 2286 NM_001135208 /// NM_004470 /// NM_057092 /// XM_005273848 /// XM_006718476 0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // not recorded 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation 203392_s_at NM_001328 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001328.1 /DEF=Homo sapiens C-terminal binding protein 1 (CTBP1), mRNA. /FEA=mRNA /GEN=CTBP1 /PROD=C-terminal binding protein 1 /DB_XREF=gi:4557496 /UG=Hs.239737 C-terminal binding protein 1 /FL=gb:U37408.1 gb:AF091555.1 gb:NM_001328.1" NM_001328 C-terminal binding protein 1 CTBP1 1487 NM_001012614 /// NM_001328 /// XM_005272261 /// XM_005272262 /// XM_005272263 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0007030 // Golgi organization // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019079 // viral genome replication // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031065 // positive regulation of histone deacetylation // inferred from mutant phenotype /// 0034401 // regulation of transcription by chromatin organization // inferred from mutant phenotype /// 0035067 // negative regulation of histone acetylation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from sequence or structural similarity /// 0051726 // regulation of cell cycle // inferred from mutant phenotype /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090241 // negative regulation of histone H4 acetylation // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity "0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // traceable author statement /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction" 203393_at BE973687 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE973687 /FEA=EST /DB_XREF=gi:10587023 /DB_XREF=est:601680868F1 /CLONE=IMAGE:3951041 /UG=Hs.250666 hairy (Drosophila)-homolog /FL=gb:AF264785.1 gb:NM_005524.2 BE973687 hes family bHLH transcription factor 1 HES1 3280 NM_005524 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021555 // midbrain-hindbrain boundary morphogenesis // inferred from electronic annotation /// 0021557 // oculomotor nerve development // inferred from electronic annotation /// 0021558 // trochlear nerve development // inferred from electronic annotation /// 0021575 // hindbrain morphogenesis // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042668 // auditory receptor cell fate determination // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045608 // negative regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045977 // positive regulation of mitotic cell cycle, embryonic // inferred from sequence or structural similarity /// 0046331 // lateral inhibition // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061106 // negative regulation of stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061626 // pharyngeal arch artery morphogenesis // inferred from sequence or structural similarity /// 0072012 // glomerulus vasculature development // inferred from electronic annotation /// 0072049 // comma-shaped body morphogenesis // inferred from electronic annotation /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072141 // renal interstitial cell development // inferred from electronic annotation /// 0072282 // metanephric nephron tubule morphogenesis // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000227 // negative regulation of pancreatic A cell differentiation // inferred from electronic annotation /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype /// 2000974 // negative regulation of pro-B cell differentiation // inferred from mutant phenotype /// 2000978 // negative regulation of forebrain neuron differentiation // inferred from sequence or structural similarity /// 2000981 // negative regulation of inner ear receptor cell differentiation // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071820 // N-box binding // inferred from sequence or structural similarity 203394_s_at BE973687 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE973687 /FEA=EST /DB_XREF=gi:10587023 /DB_XREF=est:601680868F1 /CLONE=IMAGE:3951041 /UG=Hs.250666 hairy (Drosophila)-homolog /FL=gb:AF264785.1 gb:NM_005524.2 BE973687 hes family bHLH transcription factor 1 HES1 3280 NM_005524 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021555 // midbrain-hindbrain boundary morphogenesis // inferred from electronic annotation /// 0021557 // oculomotor nerve development // inferred from electronic annotation /// 0021558 // trochlear nerve development // inferred from electronic annotation /// 0021575 // hindbrain morphogenesis // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042668 // auditory receptor cell fate determination // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045608 // negative regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045977 // positive regulation of mitotic cell cycle, embryonic // inferred from sequence or structural similarity /// 0046331 // lateral inhibition // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061106 // negative regulation of stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061626 // pharyngeal arch artery morphogenesis // inferred from sequence or structural similarity /// 0072012 // glomerulus vasculature development // inferred from electronic annotation /// 0072049 // comma-shaped body morphogenesis // inferred from electronic annotation /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072141 // renal interstitial cell development // inferred from electronic annotation /// 0072282 // metanephric nephron tubule morphogenesis // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000227 // negative regulation of pancreatic A cell differentiation // inferred from electronic annotation /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype /// 2000974 // negative regulation of pro-B cell differentiation // inferred from mutant phenotype /// 2000978 // negative regulation of forebrain neuron differentiation // inferred from sequence or structural similarity /// 2000981 // negative regulation of inner ear receptor cell differentiation // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071820 // N-box binding // inferred from sequence or structural similarity 203395_s_at NM_005524 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005524.2 /DEF=Homo sapiens hairy (Drosophila)-homolog (HRY), mRNA. /FEA=mRNA /GEN=HRY /PROD=hairy (Drosophila)-homolog /DB_XREF=gi:8400709 /UG=Hs.250666 hairy (Drosophila)-homolog /FL=gb:AF264785.1 gb:NM_005524.2" NM_005524 hes family bHLH transcription factor 1 HES1 3280 NM_005524 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003266 // regulation of secondary heart field cardioblast proliferation // inferred from sequence or structural similarity /// 0003281 // ventricular septum development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from direct assay /// 0007219 // Notch signaling pathway // inferred from mutant phenotype /// 0007219 // Notch signaling pathway // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007262 // STAT protein import into nucleus // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0016477 // cell migration // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021555 // midbrain-hindbrain boundary morphogenesis // inferred from electronic annotation /// 0021557 // oculomotor nerve development // inferred from electronic annotation /// 0021558 // trochlear nerve development // inferred from electronic annotation /// 0021575 // hindbrain morphogenesis // inferred from electronic annotation /// 0021861 // forebrain radial glial cell differentiation // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0021984 // adenohypophysis development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0030513 // positive regulation of BMP signaling pathway // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0031016 // pancreas development // inferred from electronic annotation /// 0031018 // endocrine pancreas development // traceable author statement /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035909 // aorta morphogenesis // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0042491 // auditory receptor cell differentiation // inferred from electronic annotation /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042668 // auditory receptor cell fate determination // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045608 // negative regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045977 // positive regulation of mitotic cell cycle, embryonic // inferred from sequence or structural similarity /// 0046331 // lateral inhibition // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048667 // cell morphogenesis involved in neuron differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0050767 // regulation of neurogenesis // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060164 // regulation of timing of neuron differentiation // inferred from electronic annotation /// 0060253 // negative regulation of glial cell proliferation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061106 // negative regulation of stomach neuroendocrine cell differentiation // inferred from electronic annotation /// 0061309 // cardiac neural crest cell development involved in outflow tract morphogenesis // inferred from sequence or structural similarity /// 0061626 // pharyngeal arch artery morphogenesis // inferred from sequence or structural similarity /// 0072012 // glomerulus vasculature development // inferred from electronic annotation /// 0072049 // comma-shaped body morphogenesis // inferred from electronic annotation /// 0072050 // S-shaped body morphogenesis // inferred from electronic annotation /// 0072141 // renal interstitial cell development // inferred from electronic annotation /// 0072282 // metanephric nephron tubule morphogenesis // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from sequence or structural similarity /// 0097150 // neuronal stem cell maintenance // inferred from expression pattern /// 2000227 // negative regulation of pancreatic A cell differentiation // inferred from electronic annotation /// 2000737 // negative regulation of stem cell differentiation // inferred from mutant phenotype /// 2000974 // negative regulation of pro-B cell differentiation // inferred from mutant phenotype /// 2000978 // negative regulation of forebrain neuron differentiation // inferred from sequence or structural similarity /// 2000981 // negative regulation of inner ear receptor cell differentiation // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0071820 // N-box binding // inferred from sequence or structural similarity 203396_at NM_002789 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002789.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 4 (PSMA4), mRNA. /FEA=mRNA /GEN=PSMA4 /PROD=proteasome (prosome, macropain) subunit, alphatype, 4 /DB_XREF=gi:4506184 /UG=Hs.251531 proteasome (prosome, macropain) subunit, alpha type, 4 /FL=gb:BC005361.1 gb:NM_002789.1" NM_002789 "proteasome (prosome, macropain) subunit, alpha type, 4" PSMA4 5685 NM_001102667 /// NM_001102668 /// NM_002789 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" "0000502 // proteasome complex // traceable author statement /// 0000932 // cytoplasmic mRNA processing body // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0019773 // proteasome core complex, alpha-subunit complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay" 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203397_s_at BF063271 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF063271 /FEA=EST /DB_XREF=gi:10822181 /DB_XREF=est:7h87d05.x1 /CLONE=IMAGE:3322953 /UG=Hs.278611 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) /FL=gb:NM_004482.2 BF063271 polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 2591 NM_004482 /// XM_005246449 /// XM_006712402 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203398_s_at NM_004482 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004482.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3), mRNA. /FEA=mRNA /GEN=GALNT3 /PROD=polypeptide N-acetylgalactosaminyltransferase 3 /DB_XREF=gi:9945386 /UG=Hs.278611 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) /FL=gb:NM_004482.2" NM_004482 polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 2591 NM_004482 /// XM_005246449 /// XM_006712402 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018242 // protein O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein O-linked glycosylation via threonine // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203399_x_at NM_021016 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021016.1 /DEF=Homo sapiens pregnancy specific beta-1-glycoprotein 3 (PSG3), mRNA. /FEA=mRNA /GEN=PSG3 /PROD=pregnancy specific beta-1-glycoprotein 3 /DB_XREF=gi:11036637 /UG=Hs.282847 pregnancy specific beta-1-glycoprotein 3 /FL=gb:NM_021016.1 gb:M34420.1 gb:M23575.1 gb:M93061.1" NM_021016 pregnancy specific beta-1-glycoprotein 11 /// pregnancy specific beta-1-glycoprotein 3 PSG11 /// PSG3 5671 /// 5680 NM_001113410 /// NM_002785 /// NM_021016 /// NM_203287 0006952 // defense response // traceable author statement /// 0007565 // female pregnancy // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203400_s_at NM_001063 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001063.1 /DEF=Homo sapiens transferrin (TF), mRNA. /FEA=mRNA /GEN=TF /PROD=transferrin precursor /DB_XREF=gi:4557870 /UG=Hs.284176 transferrin /FL=gb:M12530.1 gb:NM_001063.1" NM_001063 transferrin TF 7018 NM_001063 0001895 // retina homeostasis // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030120 // vesicle coat // inferred from direct assay /// 0030139 // endocytic vesicle // inferred from direct assay /// 0034774 // secretory granule lumen // traceable author statement /// 0045178 // basal part of cell // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay /// 0097433 // dense body // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203401_at NM_002765 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002765.1 /DEF=Homo sapiens phosphoribosyl pyrophosphate synthetase 2 (PRPS2), mRNA. /FEA=mRNA /GEN=PRPS2 /PROD=phosphoribosyl pyrophosphate synthetase 2 /DB_XREF=gi:4506128 /UG=Hs.2910 phosphoribosyl pyrophosphate synthetase 2 /FL=gb:NM_002765.1" NM_002765 phosphoribosyl pyrophosphate synthetase 2 PRPS2 5634 NM_001039091 /// NM_002765 0006015 // 5-phosphoribose 1-diphosphate biosynthetic process // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019693 // ribose phosphate metabolic process // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044249 // cellular biosynthetic process // inferred from electronic annotation 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016208 // AMP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043531 // ADP binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203402_at AL520102 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL520102 /FEA=EST /DB_XREF=gi:12783595 /DB_XREF=est:AL520102 /CLONE=CS0DB005YO14 (3 prime) /UG=Hs.298184 potassium voltage-gated channel, shaker-related subfamily, beta member 2 /FL=gb:U33429.1 gb:AF029749.1 gb:NM_003636.1" AL520102 "potassium voltage-gated channel, shaker-related subfamily, beta member 2" KCNAB2 8514 NM_001199860 /// NM_001199861 /// NM_001199862 /// NM_001199863 /// NM_003636 /// NM_172130 /// XM_005263511 /// XM_005263512 /// XM_005263513 /// XM_005263514 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from sequence or structural similarity 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement 203403_s_at NM_005977 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005977.1 /DEF=Homo sapiens ring finger protein (C3H2C3 type) 6 (RNF6), mRNA. /FEA=mRNA /GEN=RNF6 /PROD=ring finger protein (C3H2C3 type) 6 /DB_XREF=gi:5174652 /UG=Hs.32597 ring finger protein (C3H2C3 type) 6 /FL=gb:NM_005977.1" NM_005977 ring finger protein (C3H2C3 type) 6 RNF6 6049 NM_005977 /// NM_183043 /// NM_183044 /// NM_183045 /// XM_005266485 /// XM_005266486 /// XM_006719854 "0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from sequence or structural similarity /// 0044314 // protein K27-linked ubiquitination // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0060765 // regulation of androgen receptor signaling pathway // inferred from mutant phenotype /// 0070936 // protein K48-linked ubiquitination // inferred from sequence or structural similarity /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from physical interaction 203404_at NM_014782 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014782.1 /DEF=Homo sapiens KIAA0512 gene product (KIAA0512), mRNA. /FEA=mRNA /GEN=KIAA0512 /PROD=KIAA0512 gene product /DB_XREF=gi:7662161 /UG=Hs.48924 KIAA0512 gene product; ALEX2 /FL=gb:AB011084.1 gb:NM_014782.1" NM_014782 "armadillo repeat containing, X-linked 2" ARMCX2 9823 NM_001282231 /// NM_014782 /// NM_177949 /// XM_005278109 /// XM_005278110 /// XM_005278111 /// XM_005278113 /// XM_005278114 /// XM_005278115 /// XM_005278116 /// XM_005278117 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203405_at NM_003720 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003720.1 /DEF=Homo sapiens Down syndrome critical region gene 2 (DSCR2), mRNA. /FEA=mRNA /GEN=DSCR2 /PROD=Down syndrome critical region protein 2 /DB_XREF=gi:4505022 /UG=Hs.5198 Down syndrome critical region gene 2 /FL=gb:BC003619.1 gb:NM_003720.1" NM_003720 "proteasome (prosome, macropain) assembly chaperone 1" PSMG1 8624 NM_001261824 /// NM_003720 /// NM_203433 /// NR_049728 0043248 // proteasome assembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203406_at NM_005926 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005926.1 /DEF=Homo sapiens microfibrillar-associated protein 1 (MFAP1), mRNA. /FEA=mRNA /GEN=MFAP1 /PROD=microfibrillar-associated protein 1 /DB_XREF=gi:5174552 /UG=Hs.61418 microfibrillar-associated protein 1 /FL=gb:U04209.1 gb:NM_005926.1" NM_005926 microfibrillar-associated protein 1 MFAP1 4236 NM_005926 0030198 // extracellular matrix organization // traceable author statement 0001527 // microfibril // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203407_at NM_002705 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002705.1 /DEF=Homo sapiens periplakin (PPL), mRNA. /FEA=mRNA /GEN=PPL /PROD=periplakin /DB_XREF=gi:4505992 /UG=Hs.74304 periplakin /FL=gb:AF001691.1 gb:NM_002705.1" NM_002705 periplakin PPL 5493 NM_002705 /// XM_006720902 0031424 // keratinization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203408_s_at NM_002971 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002971.1 /DEF=Homo sapiens special AT-rich sequence binding protein 1 (binds to nuclear matrixscaffold-associating DNAs) (SATB1), mRNA. /FEA=mRNA /GEN=SATB1 /PROD=special AT-rich sequence binding protein 1(binds to nuclear matrixscaffold-associating DNAs) /DB_XREF=gi:4506790 /UG=Hs.74592 special AT-rich sequence binding protein 1 (binds to nuclear matrixscaffold-associating DNAs) /FL=gb:M97287.1 gb:NM_002971.1" NM_002971 SATB homeobox 1 SATB1 6304 NM_001131010 /// NM_001195470 /// NM_002971 /// XM_006713280 /// XM_006713281 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0008544 // epidermis development // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016571 // histone methylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0043367 // CD4-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0043374 // CD8-positive, alpha-beta T cell differentiation // inferred from electronic annotation /// 0050798 // activated T cell proliferation // inferred from electronic annotation /// 0060004 // reflex // inferred from electronic annotation" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203409_at NM_000107 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000107.1 /DEF=Homo sapiens damage-specific DNA binding protein 2 (48kD) (DDB2), mRNA. /FEA=mRNA /GEN=DDB2 /PROD=damage-specific DNA binding protein 2 (48kD) /DB_XREF=gi:4557514 /UG=Hs.77602 damage-specific DNA binding protein 2 (48kD) /FL=gb:BC000093.1 gb:U18300.1 gb:NM_000107.1" NM_000107 "damage-specific DNA binding protein 2, 48kDa" DDB2 1643 NM_000107 /// XM_005252808 /// XM_006718161 /// XR_242780 "0000209 // protein polyubiquitination // inferred from direct assay /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006290 // pyrimidine dimer repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070914 // UV-damage excision repair // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 203410_at NM_006803 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006803.1 /DEF=Homo sapiens adaptor-related protein complex 3, mu 2 subunit (AP3M2), mRNA. /FEA=mRNA /GEN=AP3M2 /PROD=adaptor-related protein complex 3, mu 2 subunit /DB_XREF=gi:5802999 /UG=Hs.77770 adaptor-related protein complex 3, mu 2 subunit /FL=gb:NM_006803.1 gb:D38293.1" NM_006803 "adaptor-related protein complex 3, mu 2 subunit" AP3M2 10947 NM_001134296 /// NM_006803 /// XM_006716276 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048490 // anterograde synaptic vesicle transport // inferred from sequence or structural similarity 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030119 // AP-type membrane coat adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203411_s_at NM_005572 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005572.1 /DEF=Homo sapiens lamin AC (LMNA), mRNA. /FEA=mRNA /GEN=LMNA /PROD=lamin AC /DB_XREF=gi:5031874 /UG=Hs.77886 lamin AC /FL=gb:BC000511.1 gb:BC003162.1 gb:M13451.1 gb:NM_005572.1" NM_005572 lamin A/C LMNA 4000 NM_001257374 /// NM_001282624 /// NM_001282625 /// NM_001282626 /// NM_005572 /// NM_170707 /// NM_170708 0000278 // mitotic cell cycle // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006997 // nucleus organization // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0035105 // sterol regulatory element binding protein import into nucleus // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090343 // positive regulation of cell aging // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005638 // lamin filament // inferred from electronic annotation /// 0005638 // lamin filament // traceable author statement /// 0005652 // nuclear lamina // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203412_at NM_006767 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006767.1 /DEF=Homo sapiens leucine-zipper-like transcriptional regulator, 1 (LZTR1), mRNA. /FEA=mRNA /GEN=LZTR1 /PROD=leucine-zipper-like transcriptional regulator,1 /DB_XREF=gi:5803073 /UG=Hs.78788 leucine-zipper-like transcriptional regulator, 1 /FL=gb:NM_006767.1 gb:D38496.1" NM_006767 leucine-zipper-like transcription regulator 1 LZTR1 8216 NM_006767 "0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement" 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 203413_at NM_006159 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006159.1 /DEF=Homo sapiens nel (chicken)-like 2 (NELL2), mRNA. /FEA=mRNA /GEN=NELL2 /PROD=nel (chicken)-like 2 /DB_XREF=gi:5453765 /UG=Hs.79389 nel (chicken)-like 2 /FL=gb:D83018.1 gb:NM_006159.1" NM_006159 NEL-like 2 (chicken) NELL2 4753 NM_001145107 /// NM_001145108 /// NM_001145109 /// NM_001145110 /// NM_006159 /// XM_005268905 0007155 // cell adhesion // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 203414_at NM_012329 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012329.1 /DEF=Homo sapiens monocyte to macrophage differentiation-associated (MMD), mRNA. /FEA=mRNA /GEN=MMD /PROD=monocyte to macrophagedifferentiation-associated, precursor /DB_XREF=gi:6912507 /UG=Hs.79889 monocyte to macrophage differentiation-associated /FL=gb:NM_012329.1" NM_012329 monocyte to macrophage differentiation-associated MMD 23531 NM_012329 /// XM_006721795 /// XR_429880 0019835 // cytolysis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement 203415_at NM_013232 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013232.1 /DEF=Homo sapiens programmed cell death 6 (PDCD6), mRNA. /FEA=mRNA /GEN=PDCD6 /PROD=programmed cell death 6 /DB_XREF=gi:7019484 /UG=Hs.80019 programmed cell death 6 /FL=gb:AF035606.1 gb:U58773.1 gb:NM_013232.1" NM_013232 programmed cell death 6 PDCD6 10016 NM_001267556 /// NM_001267557 /// NM_001267558 /// NM_001267559 /// NM_013232 /// NR_073609 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // not recorded /// 0006886 // intracellular protein transport // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0032007 // negative regulation of TOR signaling // inferred from direct assay /// 0033235 // positive regulation of protein sumoylation // inferred from electronic annotation /// 0033554 // cellular response to stress // inferred from direct assay /// 0034605 // cellular response to heat // inferred from direct assay /// 0036324 // vascular endothelial growth factor receptor-2 signaling pathway // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003677 // DNA binding // inferred from electronic annotation /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0060090 // binding, bridging // inferred from mutant phenotype" 203416_at NM_000560 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000560.1 /DEF=Homo sapiens CD53 antigen (CD53), mRNA. /FEA=mRNA /GEN=CD53 /PROD=CD53 antigen /DB_XREF=gi:10834971 /UG=Hs.82212 CD53 antigen /FL=gb:NM_000560.1 gb:M60871.1 gb:M37033.1" NM_000560 CD53 molecule CD53 963 NM_000560 /// NM_001040033 /// XM_006711053 0007165 // signal transduction // non-traceable author statement /// 1901741 // positive regulation of myoblast fusion // inferred from sequence or structural similarity 0001772 // immunological synapse // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203417_at NM_017459 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017459.1 /DEF=Homo sapiens microfibrillar-associated protein 2 (MFAP2), transcript variant 1, mRNA. /FEA=mRNA /GEN=MFAP2 /PROD=microfibrillar-associated protein 2 precursor /DB_XREF=gi:9665258 /UG=Hs.83551 microfibrillar-associated protein 2 /FL=gb:U19718.1 gb:NM_017459.1 gb:NM_002403.2" NM_017459 microfibrillar-associated protein 2 MFAP2 4237 NM_001135247 /// NM_001135248 /// NM_002403 /// NM_017459 0030198 // extracellular matrix organization // traceable author statement /// 0030220 // platelet formation // inferred from electronic annotation 0001527 // microfibril // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0070051 // fibrinogen binding // inferred from electronic annotation 203418_at NM_001237 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001237.1 /DEF=Homo sapiens cyclin A2 (CCNA2), mRNA. /FEA=mRNA /GEN=CCNA2 /PROD=cyclin A /DB_XREF=gi:4502612 /UG=Hs.85137 cyclin A2 /FL=gb:NM_001237.1" NM_001237 cyclin A2 CCNA2 890 NM_001237 "0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation" 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation 203419_at NM_014727 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014727.1 /DEF=Homo sapiens KIAA0304 gene product (KIAA0304), mRNA. /FEA=mRNA /GEN=KIAA0304 /PROD=KIAA0304 gene product /DB_XREF=gi:7662045 /UG=Hs.92236 KIAA0304 gene product /FL=gb:NM_014727.1" NM_014727 lysine (K)-specific methyltransferase 2B KMT2B 9757 NM_014727 /// XM_006723513 /// XM_006723514 /// XM_006723515 "0001541 // ovarian follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009994 // oocyte differentiation // inferred from electronic annotation /// 0016458 // gene silencing // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030728 // ovulation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0048096 // chromatin-mediated maintenance of transcription // non-traceable author statement /// 0051568 // histone H3-K4 methylation // inferred from mutant phenotype /// 0051569 // regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0080182 // histone H3-K4 trimethylation // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0018024 // histone-lysine N-methyltransferase activity // inferred from electronic annotation /// 0042800 // histone methyltransferase activity (H3-K4 specific) // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203420_at NM_016255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016255.1 /DEF=Homo sapiens Autosomal Highly Conserved Protein (AHCP), mRNA. /FEA=mRNA /GEN=AHCP /PROD=Autosomal Highly Conserved Protein /DB_XREF=gi:7705267 /UG=Hs.95260 Autosomal Highly Conserved Protein /FL=gb:AF097027.1 gb:NM_016255.1" NM_016255 "family with sequence similarity 8, member A1" FAM8A1 51439 NM_016255 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203421_at NM_006034 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006034.1 /DEF=Homo sapiens p53-induced protein (PIG11), mRNA. /FEA=mRNA /GEN=PIG11 /PROD=p53-induced protein /DB_XREF=gi:5174630 /UG=Hs.96908 p53-induced protein /FL=gb:BC000443.1 gb:BC003010.1 gb:AF010315.1 gb:NM_006034.1" NM_006034 tumor protein p53 inducible protein 11 TP53I11 9537 NM_001076787 /// NM_001258320 /// NM_001258321 /// NM_001258322 /// NM_001258323 /// NM_001258324 /// NM_006034 /// XM_005253227 /// XM_005253229 /// XM_006718387 /// XR_242833 /// XR_428864 0006950 // response to stress // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203422_at NM_002691 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002691.1 /DEF=Homo sapiens polymerase (DNA directed), delta 1, catalytic subunit (125kD) (POLD1), mRNA. /FEA=mRNA /GEN=POLD1 /PROD=polymerase (DNA directed), delta 1, catalyticsubunit (125kD) /DB_XREF=gi:4505932 /UG=Hs.99890 polymerase (DNA directed), delta 1, catalytic subunit (125kD) /FL=gb:M80397.1 gb:M81735.1 gb:NM_002691.1" NM_002691 "polymerase (DNA directed), delta 1, catalytic subunit" POLD1 5424 NM_001256849 /// NM_002691 /// NR_046402 /// XM_005259006 /// XM_005259007 /// XM_005259008 /// XM_006723248 "0000084 // mitotic S phase // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // inferred from direct assay /// 0000731 // DNA synthesis involved in DNA repair // inferred from mutant phenotype /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // inferred from mutant phenotype /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred by curator /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred from mutant phenotype /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0007346 // regulation of mitotic cell cycle // not recorded /// 0009411 // response to UV // traceable author statement /// 0019985 // translesion synthesis // not recorded /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0043137 // DNA replication, removal of RNA primer // not recorded /// 0044281 // small molecule metabolic process // traceable author statement /// 0045004 // DNA replication proofreading // not recorded /// 0055089 // fatty acid homeostasis // inferred from mutant phenotype /// 0090305 // nucleic acid phosphodiester bond hydrolysis // not recorded /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" 0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016235 // aggresome // inferred from direct assay /// 0043625 // delta DNA polymerase complex // not recorded "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from mutant phenotype /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008408 // 3'-5' exonuclease activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation" 203423_at NM_002899 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002899.2 /DEF=Homo sapiens retinol-binding protein 1, cellular (RBP1), mRNA. /FEA=mRNA /GEN=RBP1 /PROD=retinol-binding protein 1, cellular /DB_XREF=gi:8400726 /UG=Hs.101850 retinol-binding protein 1, cellular /FL=gb:M11433.1 gb:NM_002899.2" NM_002899 "retinol binding protein 1, cellular" RBP1 5947 NM_001130992 /// NM_001130993 /// NM_002899 "0001523 // retinoid metabolic process // traceable author statement /// 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0006776 // vitamin A metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0044297 // cell body // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation 203424_s_at AW157548 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW157548 /FEA=EST /DB_XREF=gi:6228949 /DB_XREF=est:au83f04.x1 /CLONE=IMAGE:2782879 /UG=Hs.107169 insulin-like growth factor binding protein 5 /FL=gb:NM_000599.1 gb:M62782.1 gb:M65062.1 gb:AF055033.1 AW157548 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 203425_s_at NM_000599 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000599.1 /DEF=Homo sapiens insulin-like growth factor binding protein 5 (IGFBP5), mRNA. /FEA=mRNA /GEN=IGFBP5 /PROD=insulin-like growth factor binding protein 5 /DB_XREF=gi:10834981 /UG=Hs.107169 insulin-like growth factor binding protein 5 /FL=gb:NM_000599.1 gb:M62782.1 gb:M65062.1 gb:AF055033.1" NM_000599 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 203426_s_at M65062 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M65062.1 /DEF=Human insulin-like growth factor binding protein 5 (IGFBP-5) mRNA, complete cds. /FEA=mRNA /GEN=IGFBP5 /PROD=insulin-like growth factor binding protein 5 /DB_XREF=gi:184819 /UG=Hs.107169 insulin-like growth factor binding protein 5 /FL=gb:NM_000599.1 gb:M62782.1 gb:M65062.1 gb:AF055033.1" M65062 insulin-like growth factor binding protein 5 IGFBP5 3488 NM_000599 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0010906 // regulation of glucose metabolic process // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from electronic annotation /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0048630 // skeletal muscle tissue growth // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from direct assay /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0016942 // insulin-like growth factor binding protein complex // inferred by curator 0001968 // fibronectin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction 203427_at NM_014034 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014034.1 /DEF=Homo sapiens DKFZP547E2110 protein (DKFZP547E2110), mRNA. /FEA=mRNA /GEN=DKFZP547E2110 /PROD=DKFZP547E2110 protein /DB_XREF=gi:7661591 /UG=Hs.108110 DKFZP547E2110 protein /FL=gb:AL050261.1 gb:AF151856.1 gb:AF161495.1 gb:NM_014034.1 gb:AB028628.1" NM_014034 anti-silencing function 1A histone chaperone ASF1A 25842 NM_014034 "0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031936 // negative regulation of chromatin silencing // non-traceable author statement /// 0042692 // muscle cell differentiation // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay 203428_s_at AB028628 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB028628.1 /DEF=Homo sapiens mRNA for CIA, complete cds. /FEA=mRNA /PROD=CIA /DB_XREF=gi:8439508 /UG=Hs.108110 DKFZP547E2110 protein /FL=gb:AL050261.1 gb:AF151856.1 gb:AF161495.1 gb:NM_014034.1 gb:AB028628.1" AB028628 anti-silencing function 1A histone chaperone ASF1A 25842 NM_014034 "0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006281 // DNA repair // inferred from direct assay /// 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006334 // nucleosome assembly // inferred from direct assay /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006336 // DNA replication-independent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0031936 // negative regulation of chromatin silencing // non-traceable author statement /// 0042692 // muscle cell differentiation // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0003682 // chromatin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042393 // histone binding // inferred from direct assay 203429_s_at NM_016227 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016227.1 /DEF=Homo sapiens membrane protein CH1 (CH1), mRNA. /FEA=mRNA /GEN=CH1 /PROD=membrane protein CH1 /DB_XREF=gi:7705321 /UG=Hs.108636 membrane protein CH1 /FL=gb:AF097535.1 gb:NM_016227.1" NM_016227 SUN domain containing ossification factor SUCO 51430 NM_001282750 /// NM_001282751 /// NM_014283 /// NM_016227 /// XM_005245251 /// XM_006711374 /// XM_006711375 /// XM_006711376 0001503 // ossification // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0046850 // regulation of bone remodeling // inferred from sequence or structural similarity 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation 203430_at NM_014320 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014320.1 /DEF=Homo sapiens putative heme-binding protein (SOUL), mRNA. /FEA=mRNA /GEN=SOUL /PROD=putative heme-binding protein /DB_XREF=gi:7657602 /UG=Hs.111029 putative heme-binding protein /FL=gb:AF117616.1 gb:NM_014320.1" NM_014320 heme binding protein 2 HEBP2 23593 NM_014320 0010917 // negative regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0010940 // positive regulation of necrotic cell death // inferred from mutant phenotype /// 0035794 // positive regulation of mitochondrial membrane permeability // inferred from mutant phenotype /// 1901031 // regulation of response to reactive oxygen species // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203431_s_at NM_014715 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014715.1 /DEF=Homo sapiens KIAA0712 gene product (KIAA0712), mRNA. /FEA=mRNA /GEN=KIAA0712 /PROD=KIAA0712 gene product /DB_XREF=gi:7662261 /UG=Hs.111138 KIAA0712 gene product /FL=gb:AB018255.1 gb:NM_014715.1" NM_014715 Rho GTPase activating protein 32 ARHGAP32 9743 NM_001142685 /// NM_014715 /// XM_005271736 /// XM_006718947 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035091 // phosphatidylinositol binding // inferred from electronic annotation 203432_at AW272611 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW272611 /FEA=EST /DB_XREF=gi:6659725 /DB_XREF=est:xu22h03.x1 /CLONE=IMAGE:2800949 /UG=Hs.11355 thymopoietin /FL=gb:NM_003276.1 gb:U09086.1 AW272611 thymopoietin TMPO 7112 NM_001032283 /// NM_001032284 /// NM_003276 /// XM_005269130 /// XM_005269132 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // traceable author statement 203433_at NM_006441 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006441.1 /DEF=Homo sapiens 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) (MTHFS), mRNA. /FEA=mRNA /GEN=MTHFS /PROD=5,10-methenyltetrahydrofolate synthetase(5-formyltetrahydrofolate cyclo-ligase) /DB_XREF=gi:5453745 /UG=Hs.118131 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) /FL=gb:NM_006441.1 gb:L38928.1" NM_006441 "5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) /// ST20-MTHFS readthrough" MTHFS /// ST20-MTHFS 10588 /// 100528021 NM_001199758 /// NM_001199760 /// NM_006441 /// NR_037654 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0015942 // formate metabolic process // non-traceable author statement /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005542 // folic acid binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030272 // 5-formyltetrahydrofolate cyclo-ligase activity // inferred from direct assay /// 0030272 // 5-formyltetrahydrofolate cyclo-ligase activity // non-traceable author statement 203434_s_at AI433463 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI433463 /FEA=EST /DB_XREF=gi:4289355 /DB_XREF=est:ti65g11.x1 /CLONE=IMAGE:2136932 /UG=Hs.1298 membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) /FL=gb:J03779.1 gb:NM_007287.1 gb:NM_007288.1" AI433463 membrane metallo-endopeptidase MME 4311 NM_000902 /// NM_007287 /// NM_007288 /// NM_007289 /// XM_006713646 /// XM_006713647 0001822 // kidney development // inferred from expression pattern /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006518 // peptide metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046449 // creatinine metabolic process // inferred from mutant phenotype /// 0050435 // beta-amyloid metabolic process // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from direct assay /// 0071493 // cellular response to UV-B // inferred from direct assay /// 0090399 // replicative senescence // inferred from expression pattern 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203435_s_at NM_007287 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007287.1 /DEF=Homo sapiens membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) (MME), transcript variant 1bis, mRNA. /FEA=mRNA /GEN=MME /PROD=membrane metallo-endopeptidase /DB_XREF=gi:6042199 /UG=Hs.1298 membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) /FL=gb:J03779.1 gb:NM_007287.1 gb:NM_007288.1" NM_007287 membrane metallo-endopeptidase MME 4311 NM_000902 /// NM_007287 /// NM_007288 /// NM_007289 /// XM_006713646 /// XM_006713647 0001822 // kidney development // inferred from expression pattern /// 0002003 // angiotensin maturation // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0006518 // peptide metabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046449 // creatinine metabolic process // inferred from mutant phenotype /// 0050435 // beta-amyloid metabolic process // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from direct assay /// 0071493 // cellular response to UV-B // inferred from direct assay /// 0090399 // replicative senescence // inferred from expression pattern 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from direct assay /// 0008021 // synaptic vesicle // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0044306 // neuron projection terminus // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203436_at NM_006413 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006413.1 /DEF=Homo sapiens ribonuclease P (30kD) (RPP30), mRNA. /FEA=mRNA /GEN=RPP30 /PROD=ribonuclease P (30kD) /DB_XREF=gi:5454023 /UG=Hs.139120 ribonuclease P (30kD) /FL=gb:U77665.1 gb:NM_006413.1" NM_006413 ribonuclease P/MRP 30kDa subunit RPP30 10556 NM_001104546 /// NM_006413 /// XM_006717546 "0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // traceable author statement /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005655 // nucleolar ribonuclease P complex // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203437_at NM_003876 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003876.1 /DEF=Homo sapiens putative receptor protein (PMI), mRNA. /FEA=mRNA /GEN=PMI /PROD=putative receptor protein /DB_XREF=gi:4505900 /UG=Hs.15196 putative receptor protein /FL=gb:BC002819.1 gb:BC005268.1 gb:NM_003876.1" NM_003876 transmembrane protein 11 TMEM11 8834 NM_003876 /// NR_024547 0007005 // mitochondrion organization // inferred from mutant phenotype 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203438_at AI435828 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI435828 /FEA=EST /DB_XREF=gi:4305913 /DB_XREF=est:th79e05.x1 /CLONE=IMAGE:2124896 /UG=Hs.155223 stanniocalcin 2 /FL=gb:BC000658.1 gb:AF055460.1 gb:AB012664.1 gb:AF098462.1 gb:AF031036.1 gb:NM_003714.1 AI435828 stanniocalcin 2 STC2 8614 NM_003714 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203439_s_at BC000658 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000658.1 /DEF=Homo sapiens, stanniocalcin 2, clone MGC:1881, mRNA, complete cds. /FEA=mRNA /PROD=stanniocalcin 2 /DB_XREF=gi:12653744 /UG=Hs.155223 stanniocalcin 2 /FL=gb:BC000658.1 gb:AF055460.1 gb:AB012664.1 gb:AF098462.1 gb:AF031036.1 gb:NM_003714.1" BC000658 stanniocalcin 2 STC2 8614 NM_003714 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from electronic annotation /// 0034976 // response to endoplasmic reticulum stress // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 2001256 // regulation of store-operated calcium entry // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203440_at M34064 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M34064.1 /DEF=Human N-cadherin mRNA, complete cds. /FEA=mRNA /GEN=NCAD /DB_XREF=gi:416292 /UG=Hs.161 cadherin 2, type 1, N-cadherin (neuronal) /FL=gb:M34064.1 gb:NM_001792.1" M34064 "cadherin 2, type 1, N-cadherin (neuronal)" CDH2 1000 NM_001792 /// XM_005258181 /// XM_005258182 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203441_s_at NM_001792 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001792.1 /DEF=Homo sapiens cadherin 2, type 1, N-cadherin (neuronal) (CDH2), mRNA. /FEA=mRNA /GEN=CDH2 /PROD=cadherin 2, type 1, N-cadherin (neuronal) /DB_XREF=gi:4502720 /UG=Hs.161 cadherin 2, type 1, N-cadherin (neuronal) /FL=gb:M34064.1 gb:NM_001792.1" NM_001792 "cadherin 2, type 1, N-cadherin (neuronal)" CDH2 1000 NM_001792 /// XM_005258181 /// XM_005258182 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203442_x_at AA478965 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA478965 /FEA=EST /DB_XREF=gi:2207599 /DB_XREF=est:zv18e01.s1 /CLONE=IMAGE:754008 /UG=Hs.173043 metastasis-associated 1-like 1 /FL=gb:AB016591.1 gb:NM_004739.1 gb:AF295807.1 AA478965 echinoderm microtubule associated protein like 3 EML3 256364 NM_153265 /// XM_005273876 /// XM_005273877 /// XM_005273878 /// XM_006718489 /// XM_006718490 /// XM_006718491 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203443_at AB012922 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB012922 /DEF=Homo sapiens MTA1-L1 gene, complete cds /FEA=mRNA /DB_XREF=gi:4126426 /UG=Hs.173043 metastasis-associated 1-like 1 /FL=gb:AB016591.1 gb:NM_004739.1 gb:AF295807.1" AB012922 echinoderm microtubule associated protein like 3 EML3 256364 NM_153265 /// XM_005273876 /// XM_005273877 /// XM_005273878 /// XM_006718489 /// XM_006718490 /// XM_006718491 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203444_s_at NM_004739 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004739.1 /DEF=Homo sapiens metastasis-associated 1-like 1 (MTA1L1), mRNA. /FEA=mRNA /GEN=MTA1L1 /PROD=metastasis-associated 1-like 1 /DB_XREF=gi:4758739 /UG=Hs.173043 metastasis-associated 1-like 1 /FL=gb:AB016591.1 gb:NM_004739.1 gb:AF295807.1" NM_004739 "metastasis associated 1 family, member 2" MTA2 9219 NM_004739 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006333 // chromatin assembly or disassembly // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0000118 // histone deacetylase complex // traceable author statement /// 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016581 // NuRD complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001103 // RNA polymerase II repressing transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203445_s_at NM_005730 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005730.1 /DEF=Homo sapiens conserved gene amplified in osteosarcoma (OS4), mRNA. /FEA=mRNA /GEN=OS4 /PROD=conserved gene amplified in osteosarcoma /DB_XREF=gi:5031964 /UG=Hs.180669 conserved gene amplified in osteosarcoma /FL=gb:U81556.1 gb:NM_005730.1" NM_005730 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2" CTDSP2 10106 NM_005730 /// XM_005268556 0006470 // protein dephosphorylation // inferred from direct assay /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008420 // CTD phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203446_s_at NM_000276 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000276.2 /DEF=Homo sapiens oculocerebrorenal syndrome of Lowe (OCRL), transcript variant a, mRNA. /FEA=mRNA /GEN=OCRL /PROD=phosphatidylinositol polyphosphate5-phosphatase, isoform a /DB_XREF=gi:13325071 /UG=Hs.181060 oculocerebrorenal syndrome of Lowe /FL=gb:U57627.2 gb:NM_000276.2" NM_000276 oculocerebrorenal syndrome of Lowe OCRL 4952 NM_000276 /// NM_001587 /// XM_005262421 /// XM_005262422 /// XM_006724760 /// XM_006724761 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006629 // lipid metabolic process // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // inferred from direct assay /// 0032855 // positive regulation of Rac GTPase activity // inferred from direct assay /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046856 // phosphatidylinositol dephosphorylation // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0001750 // photoreceptor outer segment // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // traceable author statement /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004439 // phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from physical interaction /// 0052745 // inositol phosphate phosphatase activity // non-traceable author statement" 203447_at AU157008 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU157008 /FEA=EST /DB_XREF=gi:11018529 /DB_XREF=est:AU157008 /CLONE=PLACE1005711 /UG=Hs.193725 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 /FL=gb:NM_005047.1" AU157008 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 5" PSMD5 5711 NM_001270427 /// NM_005047 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070682 // proteasome regulatory particle assembly // traceable author statement" "0000502 // proteasome complex // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0008540 // proteasome regulatory particle, base subcomplex // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity" 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044183 // protein binding involved in protein folding // inferred from electronic annotation 203448_s_at AI347136 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI347136 /FEA=EST /DB_XREF=gi:4084342 /DB_XREF=est:tc04a11.x1 /CLONE=IMAGE:2062844 /UG=Hs.194562 telomeric repeat binding factor (NIMA-interacting) 1 /FL=gb:U40705.1 gb:NM_017489.1 AI347136 telomeric repeat binding factor (NIMA-interacting) 1 TERF1 7013 NM_003218 /// NM_017489 /// XM_005251291 /// XM_005251292 0000086 // G2/M transition of mitotic cell cycle // inferred from expression pattern /// 0000723 // telomere maintenance // traceable author statement /// 0001309 // age-dependent telomere shortening // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // inferred from mutant phenotype /// 0007004 // telomere maintenance via telomerase // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from direct assay /// 0010834 // telomere maintenance via telomere shortening // inferred from mutant phenotype /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from genetic interaction /// 0032214 // negative regulation of telomere maintenance via semi-conservative replication // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from genetic interaction /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay "0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from sequence or structural similarity /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation" "0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0010521 // telomerase inhibitor activity // inferred from genetic interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay" 203449_s_at NM_017489 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017489.1 /DEF=Homo sapiens telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 1, mRNA. /FEA=mRNA /GEN=TERF1 /PROD=telomeric repeat binding factor 1, isoform 1 /DB_XREF=gi:9257245 /UG=Hs.194562 telomeric repeat binding factor (NIMA-interacting) 1 /FL=gb:U40705.1 gb:NM_017489.1" NM_017489 telomeric repeat binding factor (NIMA-interacting) 1 TERF1 7013 NM_003218 /// NM_017489 /// XM_005251291 /// XM_005251292 0000086 // G2/M transition of mitotic cell cycle // inferred from expression pattern /// 0000723 // telomere maintenance // traceable author statement /// 0001309 // age-dependent telomere shortening // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007004 // telomere maintenance via telomerase // inferred from mutant phenotype /// 0007004 // telomere maintenance via telomerase // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0008156 // negative regulation of DNA replication // inferred from direct assay /// 0010834 // telomere maintenance via telomere shortening // inferred from mutant phenotype /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from genetic interaction /// 0032214 // negative regulation of telomere maintenance via semi-conservative replication // non-traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051974 // negative regulation of telomerase activity // inferred from genetic interaction /// 1900119 // positive regulation of execution phase of apoptosis // inferred from direct assay "0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from sequence or structural similarity /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation" "0003677 // DNA binding // non-traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0010521 // telomerase inhibitor activity // inferred from genetic interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay" 203450_at NM_015373 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015373.1 /DEF=Homo sapiens chromosome 22 open reading frame 2 (C22ORF2), mRNA. /FEA=mRNA /GEN=C22ORF2 /PROD=chromosome 22 open reading frame 2 /DB_XREF=gi:7656941 /UG=Hs.227637 chromosome 22 open reading frame 2 /FL=gb:AL136686.1 gb:NM_015373.1" NM_015373 chibby homolog 1 (Drosophila) CBY1 25776 NM_001002880 /// NM_015373 "0008104 // protein localization // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0042384 // cilium assembly // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 203451_at NM_003893 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003893.1 /DEF=Homo sapiens LIM domain binding 1 (LDB1), mRNA. /FEA=mRNA /GEN=LDB1 /PROD=LIM domain binding 1 /DB_XREF=gi:4504968 /UG=Hs.26002 LIM domain binding 1 /FL=gb:BC000482.1 gb:AB016485.1 gb:AF064491.1 gb:AF068652.1 gb:NM_003893.1" NM_003893 LIM domain binding 1 LDB1 8861 NM_001113407 /// NM_003893 /// XM_005270262 "0000972 // transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery // inferred from sequence or structural similarity /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // non-traceable author statement /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010669 // epithelial structure maintenance // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021702 // cerebellar Purkinje cell differentiation // inferred from electronic annotation /// 0022607 // cellular component assembly // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043973 // histone H3-K4 acetylation // inferred from sequence or structural similarity /// 0045647 // negative regulation of erythrocyte differentiation // inferred from sequence or structural similarity /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046985 // positive regulation of hemoglobin biosynthetic process // inferred from sequence or structural similarity /// 0060322 // head development // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005667 // transcription factor complex // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity 0000989 // transcription factor binding transcription factor activity // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001158 // enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from physical interaction /// 0030274 // LIM domain binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043621 // protein self-association // inferred from electronic annotation 203452_at NM_012200 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012200.2 /DEF=Homo sapiens beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) (B3GAT3), mRNA. /FEA=mRNA /GEN=B3GAT3 /PROD=beta-1,3-glucuronyltransferase 3 /DB_XREF=gi:12408653 /UG=Hs.26492 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) /FL=gb:NM_012200.2 gb:AB009598.1" NM_012200 "beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)" B3GAT3 26229 NM_001288721 /// NM_001288722 /// NM_001288723 /// NM_012200 /// NR_109991 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from direct assay /// 0050651 // dermatan sulfate proteoglycan biosynthetic process // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0015018 // galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity // non-traceable author statement /// 0015020 // glucuronosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203453_at NM_001038 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001038.1 /DEF=Homo sapiens sodium channel, nonvoltage-gated 1 alpha (SCNN1A), mRNA. /FEA=mRNA /GEN=SCNN1A /PROD=sodium channel, nonvoltage-gated 1 alpha /DB_XREF=gi:4506814 /UG=Hs.2794 sodium channel, nonvoltage-gated 1 alpha /FL=gb:NM_001038.1" NM_001038 "sodium channel, non-voltage-gated 1 alpha subunit" SCNN1A 6337 NM_001038 /// NM_001159575 /// NM_001159576 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0050878 // regulation of body fluid levels // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0055078 // sodium ion homeostasis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005929 // cilium // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031514 // motile cilium // inferred from direct assay /// 0034706 // sodium channel complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0060170 // ciliary membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005272 // sodium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015280 // ligand-gated sodium channel activity // inferred from direct assay /// 0050699 // WW domain binding // inferred from physical interaction 203454_s_at NM_004045 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004045.1 /DEF=Homo sapiens ATX1 (antioxidant protein 1, yeast) homolog 1 (ATOX1), mRNA. /FEA=mRNA /GEN=ATOX1 /PROD=ATX1 (antioxidant protein 1, yeast) homolog 1 /DB_XREF=gi:4757803 /UG=Hs.279910 ATX1 (antioxidant protein 1, yeast) homolog 1 /FL=gb:NM_004045.1" NM_004045 antioxidant 1 copper chaperone ATOX1 475 NM_004045 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // traceable author statement /// 0006878 // cellular copper ion homeostasis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0030001 // metal ion transport // inferred from electronic annotation 0005829 // cytosol // traceable author statement 0005507 // copper ion binding // inferred from direct assay /// 0016530 // metallochaperone activity // traceable author statement /// 0016531 // copper chaperone activity // inferred from direct assay /// 0032767 // copper-dependent protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203455_s_at NM_002970 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002970.1 /DEF=Homo sapiens spermidinespermine N1-acetyltransferase (SAT), mRNA. /FEA=mRNA /GEN=SAT /PROD=spermidinespermine N1-acetyltransferase /DB_XREF=gi:4506788 /UG=Hs.28491 spermidinespermine N1-acetyltransferase /FL=gb:BC002503.1 gb:M77693.1 gb:NM_002970.1" NM_002970 spermidine/spermine N1-acetyltransferase 1 SAT1 6303 NM_002970 /// NR_027783 0001525 // angiogenesis // inferred from expression pattern /// 0006595 // polyamine metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // traceable author statement /// 0006598 // polyamine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009447 // putrescine catabolic process // inferred from electronic annotation /// 0032918 // spermidine acetylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0004145 // diamine N-acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019809 // spermidine binding // inferred from electronic annotation" 203456_at NM_007213 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007213.1 /DEF=Homo sapiens JM4 protein (JM4), mRNA. /FEA=mRNA /GEN=JM4 /PROD=JM4 protein /DB_XREF=gi:6005793 /UG=Hs.29595 JM4 protein /FL=gb:AJ005896.1 gb:NM_007213.1" NM_007213 "PRA1 domain family, member 2" PRAF2 11230 NM_007213 0000045 // autophagic vacuole assembly // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006914 // autophagy // inferred from mutant phenotype /// 0006914 // autophagy // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0032266 // phosphatidylinositol-3-phosphate binding // not recorded /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // not recorded" 203457_at NM_003569 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003569.1 /DEF=Homo sapiens syntaxin 7 (STX7), mRNA. /FEA=mRNA /GEN=STX7 /PROD=syntaxin 7 /DB_XREF=gi:4507294 /UG=Hs.299166 syntaxin 7 /FL=gb:U77942.1 gb:NM_003569.1" NM_003569 syntaxin 7 STX7 8417 NM_003569 0006886 // intracellular protein transport // not recorded /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0016079 // synaptic vesicle exocytosis // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031201 // SNARE complex // not recorded /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // not recorded /// 0000149 // SNARE binding // inferred from direct assay /// 0005484 // SNAP receptor activity // not recorded 203458_at AI951454 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI951454 /FEA=EST /DB_XREF=gi:5743690 /DB_XREF=est:wx67b10.x1 /CLONE=IMAGE:2548699 /UG=Hs.301540 sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) /FL=gb:M76231.1 gb:NM_003124.1" AI951454 "sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)" SPR 6697 NM_003124 0006729 // tetrahydrobiopterin biosynthetic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004757 // sepiapterin reductase activity // inferred from sequence or structural similarity /// 0004757 // sepiapterin reductase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement 203459_s_at NM_022575 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022575.1 /DEF=Homo sapiens vacuolar protein sorting 16 (yeast homolog) (VPS16), mRNA. /FEA=mRNA /GEN=VPS16 /PROD=vacuolar protein sorting 16 (yeast homolog) /DB_XREF=gi:12007657 /UG=Hs.302441 vacuolar protein sorting 16 (yeast homolog) /FL=gb:AF308801.1 gb:NM_022575.1" NM_022575 vacuolar protein sorting 16 homolog (S. cerevisiae) VPS16 64601 NM_022575 /// NM_080413 /// NM_080414 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005770 // late endosome // inferred from direct assay /// 0005884 // actin filament // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030897 // HOPS complex // inferred from direct assay /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 203460_s_at NM_007318 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007318.1 /DEF=Homo sapiens presenilin 1 (Alzheimer disease 3) (PSEN1), transcript variant I-463, mRNA. /FEA=mRNA /GEN=PSEN1 /PROD=presenilin 1 isoform I-463 /DB_XREF=gi:7549812 /UG=Hs.3260 presenilin 1 (Alzheimer disease 3) /FL=gb:U40379.1 gb:L76517.1 gb:NM_007318.1" NM_007318 presenilin 1 PSEN1 5663 NM_000021 /// NM_007318 /// NM_007319 /// XM_005267864 /// XM_005267866 "0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007175 // negative regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0015871 // choline transport // inferred from electronic annotation /// 0016080 // synaptic vesicle targeting // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016485 // protein processing // inferred from direct assay /// 0021795 // cerebral cortex cell migration // inferred from electronic annotation /// 0021870 // Cajal-Retzius cell differentiation // inferred from electronic annotation /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from direct assay /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from genetic interaction /// 0034205 // beta-amyloid formation // inferred from electronic annotation /// 0035282 // segmentation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from direct assay /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from electronic annotation /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from electronic annotation /// 0051563 // smooth endoplasmic reticulum calcium ion homeostasis // not recorded /// 0051604 // protein maturation // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // /// 0060075 // regulation of resting membrane potential // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // inferred from mutant phenotype /// 2000059 // negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation" 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from direct assay /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // not recorded /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031594 // neuromuscular junction // not recorded /// 0031965 // nuclear membrane // inferred from direct assay /// 0035253 // ciliary rootlet // not recorded /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043227 // membrane-bounded organelle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // not recorded /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // not recorded /// 0070765 // gamma-secretase complex // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0045296 // cadherin binding // not recorded 203461_at NM_001271 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001271.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), mRNA. /FEA=mRNA /GEN=CHD2 /PROD=chromodomain helicase DNA binding protein 2 /DB_XREF=gi:4557448 /UG=Hs.36787 chromodomain helicase DNA binding protein 2 /FL=gb:AF006514.1 gb:NM_001271.1" NM_001271 chromodomain helicase DNA binding protein 2 CHD2 1106 NM_001042572 /// NM_001271 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement /// 0060218 // hematopoietic stem cell differentiation // inferred from electronic annotation" 0005634 // nucleus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay 203462_x_at NM_003751 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003751.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) (EIF3S9), mRNA. /FEA=mRNA /GEN=EIF3S9 /PROD=eukaryotic translation initiation factor 3,subunit 9 (eta, 116kD) /DB_XREF=gi:4503526 /UG=Hs.57783 eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) /FL=gb:U62583.1 gb:NM_003751.1" NM_003751 "eukaryotic translation initiation factor 3, subunit B" EIF3B 8662 NM_001037283 /// NM_003751 0001731 // formation of translation preinitiation complex // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006413 // translational initiation // inferred from direct assay /// 0006413 // translational initiation // traceable author statement /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from direct assay /// 0016282 // eukaryotic 43S preinitiation complex // inferred from electronic annotation /// 0033290 // eukaryotic 48S preinitiation complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred by curator /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0032947 // protein complex scaffold // traceable author statement 203463_s_at H05668 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:H05668 /FEA=EST /DB_XREF=gi:869220 /DB_XREF=est:yl75e11.s1 /CLONE=IMAGE:43677 /UG=Hs.7407 KIAA1065 protein /FL=gb:AF062085.1 gb:AB028988.1 gb:NM_014964.1 H05668 epsin 2 /// EPN2 intronic transcript 1 (non-protein coding) EPN2 /// EPN2-IT1 22905 /// 100874309 NM_001102664 /// NM_014964 /// NM_148921 /// NR_046824 /// XM_005256539 /// XM_006721475 /// XM_006721476 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030128 // clathrin coat of endocytic vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 203464_s_at NM_014964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014964.1 /DEF=Homo sapiens KIAA1065 protein (KIAA1065), mRNA. /FEA=mRNA /GEN=KIAA1065 /PROD=KIAA1065 protein /DB_XREF=gi:7662467 /UG=Hs.7407 KIAA1065 protein /FL=gb:AF062085.1 gb:AB028988.1 gb:NM_014964.1" NM_014964 epsin 2 /// EPN2 intronic transcript 1 (non-protein coding) EPN2 /// EPN2-IT1 22905 /// 100874309 NM_001102664 /// NM_014964 /// NM_148921 /// NR_046824 /// XM_005256539 /// XM_006721475 /// XM_006721476 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030128 // clathrin coat of endocytic vesicle // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 203465_at NM_014763 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014763.1 /DEF=Homo sapiens mitochondrial ribosomal protein L19 (MRPL19), mRNA. /FEA=mRNA /GEN=MRPL19 /PROD=mitochondrial ribosomal protein L19 /DB_XREF=gi:7661911 /UG=Hs.75574 mitochondrial ribosomal protein L19 /FL=gb:D14660.1 gb:NM_014763.1" NM_014763 mitochondrial ribosomal protein L19 MRPL19 9801 NM_014763 /// XM_006712155 /// XR_427001 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003735 // structural constituent of ribosome // inferred from electronic annotation 203466_at NM_002437 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002437.1 /DEF=Homo sapiens MpV17 transgene, murine homolog, glomerulosclerosis (MPV17), mRNA. /FEA=mRNA /GEN=MPV17 /PROD=MpV17 transgene, murine homolog,glomerulosclerosis /DB_XREF=gi:4505240 /UG=Hs.75659 MpV17 transgene, murine homolog, glomerulosclerosis /FL=gb:BC001115.1 gb:NM_002437.1" NM_002437 MpV17 mitochondrial inner membrane protein MPV17 4358 NM_002437 /// XM_005264326 /// XM_005264327 /// XM_006712021 0000002 // mitochondrial genome maintenance // inferred from mutant phenotype /// 0032836 // glomerular basement membrane development // inferred from sequence or structural similarity /// 0034614 // cellular response to reactive oxygen species // inferred from sequence or structural similarity /// 0042592 // homeostatic process // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203467_at NM_002676 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002676.1 /DEF=Homo sapiens phosphomannomutase 1 (PMM1), mRNA. /FEA=mRNA /GEN=PMM1 /PROD=phosphomannomutase 1 /DB_XREF=gi:4505904 /UG=Hs.75835 phosphomannomutase 1 /FL=gb:D87810.1 gb:U62526.1 gb:U86070.1 gb:NM_002676.1" NM_002676 phosphomannomutase 1 PMM1 5372 NM_002676 /// XM_005261637 /// XM_005261638 /// XM_005261640 /// XM_005261641 /// XM_005261642 /// XR_430409 0006013 // mannose metabolic process // inferred from direct assay /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // inferred from electronic annotation /// 0009298 // GDP-mannose biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019307 // mannose biosynthetic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004615 // phosphomannomutase activity // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203468_at NM_003674 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003674.1 /DEF=Homo sapiens cyclin-dependent kinase (CDC2-like) 10 (CDK10), mRNA. /FEA=mRNA /GEN=CDK10 /PROD=cyclin-dependent kinase (CDC2-like) 10 /DB_XREF=gi:4502730 /UG=Hs.77313 cyclin-dependent kinase (CDC2-like) 10 /FL=gb:NM_003674.1" NM_003674 cyclin-dependent kinase 10 CDK10 8558 NM_001098533 /// NM_001160367 /// NM_003674 /// NM_052987 /// NM_052988 /// NR_027702 /// NR_027703 /// XM_006721308 /// XM_006721309 /// XM_006721310 /// XM_006721311 /// XM_006721312 /// XM_006721313 /// XM_006721314 /// XM_006721315 /// XM_006721316 /// XM_006721317 /// XM_006721318 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203469_s_at NM_003674 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003674.1 /DEF=Homo sapiens cyclin-dependent kinase (CDC2-like) 10 (CDK10), mRNA. /FEA=mRNA /GEN=CDK10 /PROD=cyclin-dependent kinase (CDC2-like) 10 /DB_XREF=gi:4502730 /UG=Hs.77313 cyclin-dependent kinase (CDC2-like) 10 /FL=gb:NM_003674.1" NM_003674 cyclin-dependent kinase 10 CDK10 8558 NM_001098533 /// NM_001160367 /// NM_003674 /// NM_052987 /// NM_052988 /// NR_027702 /// NR_027703 /// XM_006721308 /// XM_006721309 /// XM_006721310 /// XM_006721311 /// XM_006721312 /// XM_006721313 /// XM_006721314 /// XM_006721315 /// XM_006721316 /// XM_006721317 /// XM_006721318 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203470_s_at AI433595 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI433595 /FEA=EST /DB_XREF=gi:4290278 /DB_XREF=est:ti47f03.x1 /CLONE=IMAGE:2133629 /UG=Hs.77436 pleckstrin /FL=gb:NM_002664.1 AI433595 pleckstrin PLEK 5341 NM_002664 0002244 // hematopoietic progenitor cell differentiation // inferred from expression pattern /// 0002576 // platelet degranulation // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010572 // positive regulation of platelet activation // inferred from sequence or structural similarity /// 0010920 // negative regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0010925 // positive regulation of inositol-polyphosphate 5-phosphatase activity // inferred from direct assay /// 0030030 // cell projection organization // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from direct assay /// 0030845 // phospholipase C-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031529 // ruffle organization // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0033625 // positive regulation of integrin activation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from direct assay /// 0050849 // negative regulation of calcium-mediated signaling // non-traceable author statement /// 0060305 // regulation of cell diameter // inferred from direct assay /// 0070493 // thrombin receptor signaling pathway // inferred from direct assay /// 0070527 // platelet aggregation // inferred from sequence or structural similarity /// 0070528 // protein kinase C signaling // inferred from sequence or structural similarity /// 0070560 // protein secretion by platelet // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay "0005080 // protein kinase C binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay" 203471_s_at NM_002664 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002664.1 /DEF=Homo sapiens pleckstrin (PLEK), mRNA. /FEA=mRNA /GEN=PLEK /PROD=pleckstrin /DB_XREF=gi:4505878 /UG=Hs.77436 pleckstrin /FL=gb:NM_002664.1" NM_002664 pleckstrin PLEK 5341 NM_002664 0002244 // hematopoietic progenitor cell differentiation // inferred from expression pattern /// 0002576 // platelet degranulation // inferred from expression pattern /// 0002576 // platelet degranulation // traceable author statement /// 0006904 // vesicle docking involved in exocytosis // inferred from sequence or structural similarity /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0010572 // positive regulation of platelet activation // inferred from sequence or structural similarity /// 0010920 // negative regulation of inositol phosphate biosynthetic process // inferred from direct assay /// 0010925 // positive regulation of inositol-polyphosphate 5-phosphatase activity // inferred from direct assay /// 0030030 // cell projection organization // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from direct assay /// 0030845 // phospholipase C-inhibiting G-protein coupled receptor signaling pathway // inferred from direct assay /// 0030866 // cortical actin cytoskeleton organization // inferred from direct assay /// 0031529 // ruffle organization // inferred from direct assay /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0033625 // positive regulation of integrin activation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0046488 // phosphatidylinositol metabolic process // inferred from direct assay /// 0050849 // negative regulation of calcium-mediated signaling // non-traceable author statement /// 0060305 // regulation of cell diameter // inferred from direct assay /// 0070493 // thrombin receptor signaling pathway // inferred from direct assay /// 0070527 // platelet aggregation // inferred from sequence or structural similarity /// 0070528 // protein kinase C signaling // inferred from sequence or structural similarity /// 0070560 // protein secretion by platelet // inferred from sequence or structural similarity 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0032587 // ruffle membrane // inferred from direct assay "0005080 // protein kinase C binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from direct assay" 203472_s_at AB026256 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB026256.1 /DEF=Homo sapiens mRNA for organic anion transporter OATP-B, complete cds. /FEA=mRNA /GEN=OATP-B /PROD=organic anion transporter OATP-B /DB_XREF=gi:5006262 /UG=Hs.7884 solute carrier family 21 (organic anion transporter), member 9 /FL=gb:AB020687.1 gb:AB026256.1 gb:NM_007256.1" AB026256 "solute carrier organic anion transporter family, member 2B1" SLCO2B1 11309 NM_001145211 /// NM_001145212 /// NM_007256 /// XM_006718427 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071718 // sodium-independent icosanoid transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0015125 // bile acid transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay 203473_at NM_007256 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007256.1 /DEF=Homo sapiens solute carrier family 21 (organic anion transporter), member 9 (SLC21A9), mRNA. /FEA=mRNA /GEN=SLC21A9 /PROD=solute carrier family 21 (organic aniontransporter), member 9 /DB_XREF=gi:6005819 /UG=Hs.7884 solute carrier family 21 (organic anion transporter), member 9 /FL=gb:AB020687.1 gb:AB026256.1 gb:NM_007256.1" NM_007256 "solute carrier organic anion transporter family, member 2B1" SLCO2B1 11309 NM_001145211 /// NM_001145212 /// NM_007256 /// XM_006718427 0001889 // liver development // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015721 // bile acid and bile salt transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071718 // sodium-independent icosanoid transport // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // inferred from direct assay /// 0015125 // bile acid transmembrane transporter activity // inferred from electronic annotation /// 0015347 // sodium-independent organic anion transmembrane transporter activity // inferred from direct assay 203474_at NM_006633 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006633.1 /DEF=Homo sapiens IQ motif containing GTPase activating protein 2 (IQGAP2), mRNA. /FEA=mRNA /GEN=IQGAP2 /PROD=IQ motif containing GTPase activating protein 2 /DB_XREF=gi:5729886 /UG=Hs.78993 IQ motif containing GTPase activating protein 2 /FL=gb:U51903.1 gb:NM_006633.1" NM_006633 IQ motif containing GTPase activating protein 2 IQGAP2 10788 NM_001285460 /// NM_001285461 /// NM_001285462 /// NM_006633 /// XM_005248409 /// XM_005248410 /// XM_005248411 /// XM_005248413 /// XM_005248414 /// XM_006714522 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003779 // actin binding // traceable author statement /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay" 203475_at NM_000103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000103.1 /DEF=Homo sapiens cytochrome P450, subfamily XIX (aromatization of androgens) (CYP19), mRNA. /FEA=mRNA /GEN=CYP19 /PROD=cytochrome P450, subfamily XIX (aromatization ofandrogens) /DB_XREF=gi:4503196 /UG=Hs.79946 cytochrome P450, subfamily XIX (aromatization of androgens) /FL=gb:M18856.1 gb:M22246.1 gb:J04127.1 gb:M28420.1 gb:NM_000103.1" NM_000103 "cytochrome P450, family 19, subfamily A, polypeptide 1" CYP19A1 1588 NM_000103 /// NM_031226 /// XM_005254190 /// XM_005254191 /// XM_005254192 /// XM_006720406 0006694 // steroid biosynthetic process // traceable author statement /// 0006703 // estrogen biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // traceable author statement "0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // traceable author statement /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from direct assay" 203476_at NM_006670 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006670.1 /DEF=Homo sapiens 5T4 oncofetal trophoblast glycoprotein (5T4), mRNA. /FEA=mRNA /GEN=5T4 /PROD=5T4 oncofetal trophoblast glycoprotein /DB_XREF=gi:5729717 /UG=Hs.82128 5T4 oncofetal trophoblast glycoprotein /FL=gb:NM_006670.1" NM_006670 trophoblast glycoprotein TPBG 7162 NM_001166392 /// NM_006670 /// XM_005248763 0007155 // cell adhesion // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203477_at NM_001855 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001855.1 /DEF=Homo sapiens collagen, type XV, alpha 1 (COL15A1), mRNA. /FEA=mRNA /GEN=COL15A1 /PROD=collagen, type XV, alpha 1 /DB_XREF=gi:4502940 /UG=Hs.83164 collagen, type XV, alpha 1 /FL=gb:NM_001855.1 gb:L25286.1" NM_001855 "collagen, type XV, alpha 1" COL15A1 1306 NM_001855 0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred by curator /// 0007165 // signal transduction // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005582 // collagen type XV trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005201 // extracellular matrix structural constituent // inferred by curator 203478_at NM_002494 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002494.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 (6kD, KFYI) (NDUFC1), mRNA. /FEA=mRNA /GEN=NDUFC1 /PROD=NADH dehydrogenase (ubiquinone) 1, subcomplexunknown, 1 (6kD, KFYI) /DB_XREF=gi:4505366 /UG=Hs.84549 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 (6kD, KFYI) /FL=gb:AF047184.1 gb:AF047435.1 gb:NM_002494.1" NM_002494 "NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa" NDUFC1 4717 NM_001184986 /// NM_001184987 /// NM_001184988 /// NM_001184989 /// NM_001184990 /// NM_001184991 /// NM_002494 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203479_s_at T79216 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:T79216 /FEA=EST /DB_XREF=gi:697725 /DB_XREF=est:yd70h03.s1 /CLONE=IMAGE:113621 /UG=Hs.89519 KIAA1046 protein /FL=gb:AB028969.1 gb:NM_014928.1 T79216 OTU deubiquitinase 4 OTUD4 54726 NM_001102653 /// NM_017493 /// NM_199324 /// XM_005263079 /// XM_005263080 /// XM_005263081 0006508 // proteolysis // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203480_s_at NM_014928 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014928.1 /DEF=Homo sapiens KIAA1046 protein (KIAA1046), mRNA. /FEA=mRNA /GEN=KIAA1046 /PROD=KIAA1046 protein /DB_XREF=gi:7662459 /UG=Hs.89519 KIAA1046 protein /FL=gb:AB028969.1 gb:NM_014928.1" NM_014928 OTU deubiquitinase 4 OTUD4 54726 NM_001102653 /// NM_017493 /// NM_199324 /// XM_005263079 /// XM_005263080 /// XM_005263081 0006508 // proteolysis // inferred from electronic annotation /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203481_at AI655902 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI655902 /FEA=EST /DB_XREF=gi:4739881 /DB_XREF=est:tt41c06.x1 /CLONE=IMAGE:2243338 /UG=Hs.93581 hypothetical protein FLJ10512 /FL=gb:NM_018121.1 AI655902 "family with sequence similarity 178, member A" FAM178A 55719 NM_001136123 /// NM_001243770 /// NM_018121 /// NM_144592 /// XM_005269965 /// XM_006717913 0000785 // chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 203482_at AL133215 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL133215 /DEF=Human DNA sequence from clone RP11-108L7 on chromosome 10. contains part of the gene for a novel Insulin-like growth factor binding type protein with Kazal-type serine protease inhibitor domain, the gene for a novel protein similar to rat tricarbo... /FEA=mRNA_4 /DB_XREF=gi:7228177 /UG=Hs.93581 hypothetical protein FLJ10512 /FL=gb:NM_018121.1" AL133215 "family with sequence similarity 178, member A" FAM178A 55719 NM_001136123 /// NM_001243770 /// NM_018121 /// NM_144592 /// XM_005269965 /// XM_006717913 0000785 // chromatin // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 203483_at NM_018121 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:NM_018121.1 /DEF=Homo sapiens hypothetical protein FLJ10512 (FLJ10512), mRNA. /FEA=mRNA /GEN=FLJ10512 /PROD=hypothetical protein FLJ10512 /DB_XREF=gi:8922480 /UG=Hs.93581 hypothetical protein FLJ10512 /FL=gb:NM_018121.1" NM_018121 "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G" SEMA4G 57715 NM_001203244 /// NM_017893 /// XM_005270008 /// XM_005270009 /// XM_005270010 /// XR_246101 /// XR_428710 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203484_at NM_014302 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014302.1 /DEF=Homo sapiens Sec61 gamma (SEC61G), mRNA. /FEA=mRNA /GEN=SEC61G /PROD=Sec61 gamma /DB_XREF=gi:7657545 /UG=Hs.9950 Sec61 gamma /FL=gb:AF054184.1 gb:NM_014302.1" NM_014302 Sec61 gamma subunit SEC61G 23480 NM_001012456 /// NM_014302 "0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006412 // translation // traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045047 // protein targeting to ER // inferred from sequence or structural similarity /// 0071806 // protein transmembrane transport // inferred from electronic annotation" 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation 0008565 // protein transporter activity // inferred from sequence or structural similarity /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 203485_at NM_021136 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021136.1 /DEF=Homo sapiens reticulon 1 (RTN1), mRNA. /FEA=mRNA /GEN=RTN1 /PROD=reticulon 1 /DB_XREF=gi:10863934 /UG=Hs.99947 reticulon 1 /FL=gb:NM_021136.1 gb:L10333.1 gb:L10334.1" NM_021136 reticulon 1 RTN1 6252 NM_001243115 /// NM_021136 /// NM_206852 /// NM_206857 0007165 // signal transduction // non-traceable author statement /// 0030182 // neuron differentiation // inferred from expression pattern 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // traceable author statement 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203486_s_at BF195973 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF195973 /FEA=EST /DB_XREF=gi:11083411 /DB_XREF=est:7o88c12.x1 /CLONE=IMAGE:3643391 /UG=Hs.102708 DKFZP434A043 protein /FL=gb:NM_015396.1 BF195973 armadillo repeat containing 8 ARMC8 25852 NM_001267041 /// NM_001267042 /// NM_001282342 /// NM_014154 /// NM_015396 /// NM_213654 /// XM_006713564 /// XM_006713565 /// XM_006713566 /// XM_006713567 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203487_s_at NM_015396 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015396.1 /DEF=Homo sapiens DKFZP434A043 protein (DKFZP434A043), mRNA. /FEA=mRNA /GEN=DKFZP434A043 /PROD=DKFZP434A043 protein /DB_XREF=gi:7661561 /UG=Hs.102708 DKFZP434A043 protein /FL=gb:NM_015396.1" NM_015396 armadillo repeat containing 8 ARMC8 25852 NM_001267041 /// NM_001267042 /// NM_001282342 /// NM_014154 /// NM_015396 /// NM_213654 /// XM_006713564 /// XM_006713565 /// XM_006713566 /// XM_006713567 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203488_at NM_014921 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014921.1 /DEF=Homo sapiens lectomedin-2 (KIAA0821), mRNA. /FEA=mRNA /GEN=KIAA0821 /PROD=lectomedin-2 /DB_XREF=gi:7662323 /UG=Hs.107054 lectomedin-2 /FL=gb:AF307079.1 gb:AB020628.1 gb:NM_014921.1" NM_014921 latrophilin 1 LPHN1 22859 NM_001008701 /// NM_014921 /// XM_005259818 /// XM_005259819 /// XM_006722688 /// XM_006722689 /// XM_006722690 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from sequence or structural similarity /// 0090129 // positive regulation of synapse maturation // inferred from sequence or structural similarity 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016524 // latrotoxin receptor activity // inferred from sequence or structural similarity /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from sequence or structural similarity 203489_at NM_006427 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006427.2 /DEF=Homo sapiens CD27-binding (Siva) protein (SIVA), transcript variant 1, mRNA. /FEA=mRNA /GEN=SIVA /PROD=CD27-binding (Siva) protein isoform 1 /DB_XREF=gi:11277467 /UG=Hs.112058 CD27-binding (Siva) protein /FL=gb:NM_006427.2 gb:U82938.1" NM_006427 "SIVA1, apoptosis-inducing factor" SIVA1 10572 NM_006427 /// NM_021709 0006915 // apoptotic process // inferred from electronic annotation /// 0006924 // activation-induced cell death of T cells // inferred from direct assay /// 0009615 // response to virus // inferred from sequence or structural similarity /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0001618 // virus receptor activity // inferred from sequence or structural similarity /// 0005175 // CD27 receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203490_at NM_001421 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001421.1 /DEF=Homo sapiens E74-like factor 4 (ets domain transcription factor) (ELF4), mRNA. /FEA=mRNA /GEN=ELF4 /PROD=E74-like factor 4 (ets domain transcriptionfactor) /DB_XREF=gi:4503554 /UG=Hs.151139 E74-like factor 4 (ets domain transcription factor) /FL=gb:U32645.1 gb:AF000670.1 gb:NM_001421.1" NM_001421 E74-like factor 4 (ets domain transcription factor) ELF4 2000 NM_001127197 /// NM_001421 /// XM_005262389 "0001787 // natural killer cell proliferation // inferred from sequence or structural similarity /// 0001866 // NK T cell proliferation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203491_s_at AI123527 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI123527 /FEA=EST /DB_XREF=gi:3539293 /DB_XREF=est:qa49e12.x1 /CLONE=IMAGE:1690126 /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1 AI123527 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 "0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203492_x_at AA918224 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA918224 /FEA=EST /DB_XREF=gi:3058114 /DB_XREF=est:on82h06.s1 /CLONE=IMAGE:1563227 /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1 AA918224 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 "0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203493_s_at AL525206 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL525206 /FEA=EST /DB_XREF=gi:12788699 /DB_XREF=est:AL525206 /CLONE=CS0DC005YH06 (5 prime) /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1 AL525206 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 "0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203494_s_at NM_014679 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014679.1 /DEF=Homo sapiens KIAA0092 gene product (KIAA0092), mRNA. /FEA=mRNA /GEN=KIAA0092 /PROD=KIAA0092 gene product /DB_XREF=gi:7661899 /UG=Hs.151791 KIAA0092 gene product /FL=gb:D42054.1 gb:NM_014679.1" NM_014679 centrosomal protein 57kDa CEP57 9702 NM_001243776 /// NM_001243777 /// NM_014679 /// XM_006718945 /// XM_006718946 "0000060 // protein import into nucleus, translocation // inferred from sequence or structural similarity /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0034453 // microtubule anchoring // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation 203495_at NM_014665 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014665.1 /DEF=Homo sapiens KIAA0014 gene product (KIAA0014), mRNA. /FEA=mRNA /GEN=KIAA0014 /PROD=KIAA0014 gene product /DB_XREF=gi:7661859 /UG=Hs.155650 KIAA0014 gene product /FL=gb:D25216.1 gb:NM_014665.1" NM_014665 leucine rich repeat containing 14 LRRC14 9684 NM_001272036 /// NM_014665 /// XM_005272358 /// XM_005272359 /// XM_005272360 /// XM_005272361 /// XM_006716688 /// XM_006716689 203496_s_at AF055994 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF055994.1 /DEF=Homo sapiens thyroid hormone receptor-associated protein complex component TRAP220 mRNA, complete cds. /FEA=mRNA /PROD=thyroid hormone receptor-associated proteincomplex component TRAP220 /DB_XREF=gi:3319289 /UG=Hs.15589 PPAR binding protein /FL=gb:AF055994.1 gb:NM_004774.1 gb:AF283812.1" AF055994 mediator complex subunit 1 MED1 5469 NM_004774 /// XM_005257465 /// XM_006721957 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0002154 // thyroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003406 // retinal pigment epithelium development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from electronic annotation /// 0035855 // megakaryocyte development // inferred from sequence or structural similarity /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from sequence or structural similarity /// 0048822 // enucleate erythrocyte development // inferred from electronic annotation /// 0051726 // regulation of cell cycle // non-traceable author statement /// 0060335 // positive regulation of interferon-gamma-mediated signaling pathway // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0070318 // positive regulation of G0 to G1 transition // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from mutant phenotype /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016592 // mediator complex // inferred from mutant phenotype /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from direct assay /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from direct assay /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0030375 // thyroid hormone receptor coactivator activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0042809 // vitamin D receptor binding // traceable author statement /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050693 // LBD domain binding // inferred from physical interaction 203497_at NM_004774 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004774.1 /DEF=Homo sapiens PPAR binding protein (PPARBP), mRNA. /FEA=mRNA /GEN=PPARBP /PROD=thyroid hormone receptor interactor 2 /DB_XREF=gi:4759265 /UG=Hs.15589 PPAR binding protein /FL=gb:AF055994.1 gb:NM_004774.1 gb:AF283812.1" NM_004774 mediator complex subunit 1 MED1 5469 NM_004774 /// XM_005257465 /// XM_006721957 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from sequence or structural similarity /// 0002154 // thyroid hormone mediated signaling pathway // inferred from mutant phenotype /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003406 // retinal pigment epithelium development // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006356 // regulation of transcription from RNA polymerase I promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0033160 // positive regulation of protein import into nucleus, translocation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035116 // embryonic hindlimb morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0035357 // peroxisome proliferator activated receptor signaling pathway // inferred from electronic annotation /// 0035729 // cellular response to hepatocyte growth factor stimulus // inferred from electronic annotation /// 0035855 // megakaryocyte development // inferred from sequence or structural similarity /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045665 // negative regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048821 // erythrocyte development // inferred from sequence or structural similarity /// 0048822 // enucleate erythrocyte development // inferred from electronic annotation /// 0051726 // regulation of cell cycle // non-traceable author statement /// 0060335 // positive regulation of interferon-gamma-mediated signaling pathway // inferred from electronic annotation /// 0060744 // mammary gland branching involved in thelarche // inferred from electronic annotation /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation /// 0070318 // positive regulation of G0 to G1 transition // inferred from electronic annotation /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from direct assay /// 0071383 // cellular response to steroid hormone stimulus // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay /// 2000273 // positive regulation of receptor activity // inferred from mutant phenotype /// 2000347 // positive regulation of hepatocyte proliferation // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype" 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay /// 0016592 // mediator complex // inferred from mutant phenotype /// 0032993 // protein-DNA complex // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0001047 // core promoter binding // inferred from direct assay /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from mutant phenotype /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from direct assay /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030331 // estrogen receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0030375 // thyroid hormone receptor coactivator activity // inferred from mutant phenotype /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction /// 0036033 // mediator complex binding // inferred from direct assay /// 0042809 // vitamin D receptor binding // inferred from physical interaction /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0042809 // vitamin D receptor binding // traceable author statement /// 0042974 // retinoic acid receptor binding // inferred from physical interaction /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046966 // thyroid hormone receptor binding // inferred from direct assay /// 0046966 // thyroid hormone receptor binding // inferred from physical interaction /// 0050693 // LBD domain binding // inferred from physical interaction 203498_at NM_005822 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005822.1 /DEF=Homo sapiens Down syndrome critical region gene 1-like 1 (DSCR1L1), mRNA. /FEA=mRNA /GEN=DSCR1L1 /PROD=Down syndrome critical region gene 1-like 1protein /DB_XREF=gi:5032234 /UG=Hs.156007 Down syndrome critical region gene 1-like 1 /FL=gb:D83407.1 gb:NM_005822.1" NM_005822 regulator of calcineurin 2 RCAN2 10231 NM_001251973 /// NM_001251974 /// NM_005822 /// XM_006714948 0007417 // central nervous system development // non-traceable author statement /// 0019722 // calcium-mediated signaling // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // non-traceable author statement 203499_at NM_004431 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004431.1 /DEF=Homo sapiens EphA2 (EPHA2), mRNA. /FEA=mRNA /GEN=EPHA2 /PROD=EphA2 /DB_XREF=gi:4758277 /UG=Hs.171596 EphA2 /FL=gb:M59371.1 gb:NM_004431.1" NM_004431 EPH receptor A2 EPHA2 1969 NM_004431 /// XM_005245751 /// XM_005245752 0001501 // skeletal system development // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010591 // regulation of lamellipodium assembly // inferred from mutant phenotype /// 0014028 // notochord formation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from mutant phenotype /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0033598 // mammary gland epithelial cell proliferation // inferred from sequence or structural similarity /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0036342 // post-anal tail morphogenesis // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from direct assay /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from sequence or structural similarity /// 0046849 // bone remodeling // inferred from sequence or structural similarity /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048320 // axial mesoderm formation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0060035 // notochord cell development // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from mutant phenotype /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from sequence or structural similarity /// 0070309 // lens fiber cell morphogenesis // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from mutant phenotype /// 0090004 // positive regulation of establishment of protein localization to plasma membrane // inferred from mutant phenotype 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031256 // leading edge membrane // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203500_at NM_000159 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000159.1 /DEF=Homo sapiens glutaryl-Coenzyme A dehydrogenase (GCDH), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. /FEA=mRNA /GEN=GCDH /PROD=glutaryl-Coenzyme A dehydrogenase isoform a /DB_XREF=gi:4503942 /UG=Hs.184141 glutaryl-Coenzyme A dehydrogenase /FL=gb:BC002579.1 gb:U69141.1 gb:NM_000159.1" NM_000159 glutaryl-CoA dehydrogenase GCDH 2639 NM_000159 /// NM_013976 /// NR_102316 /// NR_102317 /// XM_006722720 /// XM_006722721 0006554 // lysine catabolic process // traceable author statement /// 0006568 // tryptophan metabolic process // inferred from electronic annotation /// 0006637 // acyl-CoA metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019395 // fatty acid oxidation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046949 // fatty-acyl-CoA biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement "0000062 // fatty-acyl-CoA binding // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004361 // glutaryl-CoA dehydrogenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 203501_at NM_006102 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006102.1 /DEF=Homo sapiens plasma glutamate carboxypeptidase (PGCP), mRNA. /FEA=mRNA /GEN=PGCP /PROD=plasma glutamate carboxypeptidase /DB_XREF=gi:5174626 /UG=Hs.197335 plasma glutamate carboxypeptidase /FL=gb:AF119386.1 gb:NM_006102.1" NM_006102 carboxypeptidase Q CPQ 10404 NM_016134 /// XM_005250755 /// XM_006716498 /// XR_428374 0006508 // proteolysis // inferred from direct assay /// 0006590 // thyroid hormone generation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from sequence or structural similarity /// 0043171 // peptide catabolic process // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070573 // metallodipeptidase activity // inferred from direct assay 203502_at NM_001724 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001724.1 /DEF=Homo sapiens 2,3-bisphosphoglycerate mutase (BPGM), mRNA. /FEA=mRNA /GEN=BPGM /PROD=2,3-bisphosphoglycerate mutase /DB_XREF=gi:4502444 /UG=Hs.198365 2,3-bisphosphoglycerate mutase /FL=gb:NM_001724.1" NM_001724 "2,3-bisphosphoglycerate mutase" BPGM 669 NM_001293085 /// NM_001724 /// NM_199186 /// XM_006716096 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004082 // bisphosphoglycerate mutase activity // inferred from electronic annotation /// 0004083 // bisphosphoglycerate 2-phosphatase activity // inferred from electronic annotation /// 0004619 // phosphoglycerate mutase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation" 203503_s_at NM_004565 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004565.1 /DEF=Homo sapiens peroxisomal biogenesis factor 14 (PEX14), mRNA. /FEA=mRNA /GEN=PEX14 /PROD=peroxisomal biogenesis factor 14 /DB_XREF=gi:4758895 /UG=Hs.19851 peroxisomal biogenesis factor 14 /FL=gb:AF045186.1 gb:AB017546.1 gb:NM_004565.1" NM_004565 peroxisomal biogenesis factor 14 PEX14 5195 NM_004565 /// XM_005263470 /// XM_006710685 "0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from genetic interaction /// 0007031 // peroxisome organization // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0016560 // protein import into peroxisome matrix, docking // inferred from electronic annotation /// 0016561 // protein import into peroxisome matrix, translocation // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0034453 // microtubule anchoring // inferred from direct assay /// 0036250 // peroxisome transport along microtubule // inferred from direct assay /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0044721 // protein import into peroxisome matrix, substrate release // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0051260 // protein homooligomerization // inferred from direct assay /// 1901094 // negative regulation of protein homotetramerization // inferred from direct assay" 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0043234 // protein complex // inferred from sequence or structural similarity 0003714 // transcription corepressor activity // inferred from direct assay /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0048487 // beta-tubulin binding // inferred from physical interaction 203504_s_at NM_005502 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005502.1 /DEF=Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1), mRNA. /FEA=mRNA /GEN=ABCA1 /PROD=ATP-binding cassette, sub-family A member 1 /DB_XREF=gi:5915657 /UG=Hs.211562 ATP-binding cassette, sub-family A (ABC1), member 1 /FL=gb:AF165281.1 gb:NM_005502.1 gb:AF285167.1" NM_005502 "ATP-binding cassette, sub-family A (ABC1), member 1" ABCA1 19 NM_005502 /// XM_005251773 /// XM_005251774 /// XM_005251776 /// XM_005251778 /// XM_005251780 /// XM_006716995 "0002790 // peptide secretion // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006497 // protein lipidation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // traceable author statement /// 0010875 // positive regulation of cholesterol efflux // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from direct assay /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0033700 // phospholipid efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0034380 // high-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0038027 // apolipoprotein A-I-mediated signaling pathway // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0050702 // interleukin-1 beta secretion // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0060155 // platelet dense granule organization // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation" 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred by curator /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0008509 // anion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015485 // cholesterol binding // inferred by curator /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0019905 // syntaxin binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0034188 // apolipoprotein A-I receptor activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 203505_at AF285167 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF285167.1 /DEF=Homo sapiens ATP-binding cassette transporter 1 (ABCA1) mRNA, complete cds. /FEA=mRNA /GEN=ABCA1 /PROD=ATP-binding cassette transporter 1 /DB_XREF=gi:9755158 /UG=Hs.211562 ATP-binding cassette, sub-family A (ABC1), member 1 /FL=gb:AF165281.1 gb:NM_005502.1 gb:AF285167.1" AF285167 "ATP-binding cassette, sub-family A (ABC1), member 1" ABCA1 19 NM_005502 /// XM_005251773 /// XM_005251774 /// XM_005251776 /// XM_005251778 /// XM_005251780 /// XM_006716995 "0002790 // peptide secretion // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006497 // protein lipidation // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // traceable author statement /// 0010875 // positive regulation of cholesterol efflux // inferred from electronic annotation /// 0010887 // negative regulation of cholesterol storage // traceable author statement /// 0015914 // phospholipid transport // inferred from electronic annotation /// 0016197 // endosomal transport // inferred from direct assay /// 0030301 // cholesterol transport // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0032367 // intracellular cholesterol transport // inferred from mutant phenotype /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0033700 // phospholipid efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from mutant phenotype /// 0034380 // high-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034616 // response to laminar fluid shear stress // inferred from expression pattern /// 0038027 // apolipoprotein A-I-mediated signaling pathway // inferred from direct assay /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0050702 // interleukin-1 beta secretion // inferred from mutant phenotype /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype /// 0055098 // response to low-density lipoprotein particle // inferred from expression pattern /// 0060155 // platelet dense granule organization // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation" 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred by curator /// 0005548 // phospholipid transporter activity // inferred from direct assay /// 0008509 // anion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015485 // cholesterol binding // inferred by curator /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0017127 // cholesterol transporter activity // inferred from direct assay /// 0019905 // syntaxin binding // inferred from physical interaction /// 0031267 // small GTPase binding // inferred from physical interaction /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0034186 // apolipoprotein A-I binding // inferred from physical interaction /// 0034188 // apolipoprotein A-I receptor activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 203506_s_at NM_005120 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005120.1 /DEF=Homo sapiens trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit) (TNRC11), mRNA. /FEA=mRNA /GEN=TNRC11 /PROD=trinucleotide repeat containing 11(THR-associated protein, 230 kDa subunit) /DB_XREF=gi:4827041 /UG=Hs.211607 trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit) /FL=gb:U80742.1 gb:AF071309.1 gb:AF117755.1 gb:NM_005120.1" NM_005120 mediator complex subunit 12 MED12 9968 NM_005120 /// XM_005262317 /// XM_005262319 "0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0030518 // intracellular steroid hormone receptor signaling pathway // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090245 // axis elongation involved in somitogenesis // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016592 // mediator complex // inferred from direct assay 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // inferred from direct assay /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // non-traceable author statement /// 0042809 // vitamin D receptor binding // non-traceable author statement /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 203507_at NM_001251 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001251.1 /DEF=Homo sapiens CD68 antigen (CD68), mRNA. /FEA=mRNA /GEN=CD68 /PROD=CD68 antigen /DB_XREF=gi:4557434 /UG=Hs.246381 CD68 antigen /FL=gb:NM_001251.1" NM_001251 "CD68 molecule /// uncharacterized LOC101928634 /// small nucleolar RNA, H/ACA box 67" CD68 /// LOC101928634 /// SNORA67 968 /// 26781 /// 101928634 NM_001040059 /// NM_001251 /// NR_002912 /// XR_244579 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0006413 // translational initiation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation" 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 203508_at NM_001066 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001066.1 /DEF=Homo sapiens tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), mRNA. /FEA=mRNA /GEN=TNFRSF1B /PROD=tumor necrosis factor receptor 2 (75kD) /DB_XREF=gi:4507576 /UG=Hs.256278 tumor necrosis factor receptor superfamily, member 1B /FL=gb:M32315.1 gb:M55994.1 gb:NM_001066.1" NM_001066 "tumor necrosis factor receptor superfamily, member 1B" TNFRSF1B 7133 NM_001066 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050779 // RNA destabilization // inferred from electronic annotation /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043196 // varicosity // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005031 // tumor necrosis factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203509_at NM_003105 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003105.2 /DEF=Homo sapiens sortilin-related receptor, L(DLR class) A repeats-containing (SORL1), mRNA. /FEA=mRNA /GEN=SORL1 /PROD=sortilin-related receptor, L(DLR class) Arepeats-containing /DB_XREF=gi:6325473 /UG=Hs.278571 sortilin-related receptor, L(DLR class) A repeats-containing /FL=gb:U60975.2 gb:NM_003105.2" NM_003105 "sortilin-related receptor, L(DLR class) A repeats containing" SORL1 6653 NM_003105 0000042 // protein targeting to Golgi // inferred from direct assay /// 0006605 // protein targeting // inferred from direct assay /// 0006605 // protein targeting // inferred from mutant phenotype /// 0006622 // protein targeting to lysosome // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0032460 // negative regulation of protein oligomerization // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045053 // protein retention in Golgi apparatus // inferred from direct assay /// 0045732 // positive regulation of protein catabolic process // inferred from direct assay /// 0050768 // negative regulation of neurogenesis // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from direct assay /// 0070863 // positive regulation of protein exit from endoplasmic reticulum // inferred from mutant phenotype /// 1901215 // negative regulation of neuron death // inferred from sequence or structural similarity /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from mutant phenotype /// 1902771 // positive regulation of choline O-acetyltransferase activity // inferred from sequence or structural similarity /// 1902948 // negative regulation of tau-protein kinase activity // inferred from sequence or structural similarity /// 1902953 // positive regulation of ER to Golgi vesicle-mediated transport // inferred from mutant phenotype /// 1902955 // positive regulation of early endosome to recycling endosome transport // inferred from mutant phenotype /// 1902960 // negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from direct assay /// 1902960 // negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902963 // negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process // inferred from mutant phenotype /// 1902966 // positive regulation of protein localization to early endosome // inferred from mutant phenotype /// 1902997 // negative regulation of neurofibrillary tangle assembly // inferred from sequence or structural similarity /// 2001137 // positive regulation of endocytic recycling // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from mutant phenotype /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031985 // Golgi cisterna // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from mutant phenotype /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001540 // beta-amyloid binding // inferred from direct assay /// 0001540 // beta-amyloid binding // inferred from physical interaction /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030169 // low-density lipoprotein particle binding // inferred from physical interaction /// 0030306 // ADP-ribosylation factor binding // inferred from physical interaction 203510_at BG170541 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG170541 /FEA=EST /DB_XREF=gi:12677244 /DB_XREF=est:602322942F1 /CLONE=IMAGE:4425947 /UG=Hs.285754 met proto-oncogene (hepatocyte growth factor receptor) /FL=gb:J02958.1 gb:NM_000245.1 BG170541 "MET proto-oncogene, receptor tyrosine kinase" MET 4233 NM_000245 /// NM_001127500 /// XM_006715988 /// XM_006715989 /// XM_006715990 /// XM_006715991 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010828 // positive regulation of glucose transport // inferred from electronic annotation /// 0014812 // muscle cell migration // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from mutant phenotype /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005008 // hepatocyte growth factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction" 203511_s_at AF041432 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF041432.1 /DEF=Homo sapiens bet3 (BET3) mRNA, complete cds. /FEA=mRNA /GEN=BET3 /PROD=bet3 /DB_XREF=gi:2791803 /UG=Hs.288013 similar to yeast BET3 (S. cerevisiae) /FL=gb:AF041432.1 gb:NM_014408.1" AF041432 trafficking protein particle complex 3 TRAPPC3 27095 NM_001270894 /// NM_001270895 /// NM_001270896 /// NM_001270897 /// NM_014408 /// NR_073097 /// NR_073098 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0030008 // TRAPP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203512_at NM_014408 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014408.1 /DEF=Homo sapiens similar to yeast BET3 (S. cerevisiae) (BET3), mRNA. /FEA=mRNA /GEN=BET3 /PROD=similar to yeast BET3 (S. cerevisiae) /DB_XREF=gi:7656925 /UG=Hs.288013 similar to yeast BET3 (S. cerevisiae) /FL=gb:AF041432.1 gb:NM_014408.1" NM_014408 trafficking protein particle complex 3 TRAPPC3 27095 NM_001270894 /// NM_001270895 /// NM_001270896 /// NM_001270897 /// NM_014408 /// NR_073097 /// NR_073098 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0030008 // TRAPP complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203513_at NM_025137 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_025137.1 /DEF=Homo sapiens hypothetical protein FLJ21439 (FLJ21439), mRNA. /FEA=mRNA /GEN=FLJ21439 /PROD=hypothetical protein FLJ21439 /DB_XREF=gi:13376718 /UG=Hs.288872 hypothetical protein FLJ21439 /FL=gb:NM_025137.1" NM_025137 spastic paraplegia 11 (autosomal recessive) SPG11 80208 NM_001160227 /// NM_025137 /// XM_005254694 /// XM_005254695 /// XM_006720699 /// XM_006720700 /// XM_006720701 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203514_at BF971923 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF971923 /FEA=EST /DB_XREF=gi:12339138 /DB_XREF=est:602240326F1 /CLONE=IMAGE:4328791 /UG=Hs.29282 mitogen-activated protein kinase kinase kinase 3 /FL=gb:U78876.1 gb:NM_002401.1 BF971923 mitogen-activated protein kinase kinase kinase 3 MAP3K3 4215 NM_002401 /// NM_203351 /// XM_005257376 /// XM_005257377 /// XM_005257378 /// XM_006721909 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0046777 // protein autophosphorylation // inferred from direct assay 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203515_s_at NM_006556 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006556.1 /DEF=Homo sapiens phosphomevalonate kinase (PMVK), mRNA. /FEA=mRNA /GEN=PMVK /PROD=phosphomevalonate kinase /DB_XREF=gi:5729979 /UG=Hs.30954 phosphomevalonate kinase /FL=gb:L77213.1 gb:NM_006556.1" NM_006556 phosphomevalonate kinase PMVK 10654 NM_006556 "0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019287 // isopentenyl diphosphate biosynthetic process, mevalonate pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070723 // response to cholesterol // inferred from expression pattern" 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004631 // phosphomevalonate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203516_at NM_003098 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003098.1 /DEF=Homo sapiens syntrophin, alpha 1(dystrophin-associated protein A1, 59kD, acidic component) (SNTA1), mRNA. /FEA=mRNA /GEN=SNTA1 /PROD=syntrophin, alpha 1(dystrophin-associatedprotein A1, 59kD, acidic component) /DB_XREF=gi:4507136 /UG=Hs.31121 syntrophin, alpha 1(dystrophin-associated protein A1, 59kD, acidic component) /FL=gb:U40571.1 gb:NM_003098.1" NM_003098 "syntrophin, alpha 1" SNTA1 6640 NM_003098 /// XM_005260517 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003117 // regulation of vasoconstriction by circulating norepinephrine // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // inferred from mutant phenotype /// 1902305 // regulation of sodium ion transmembrane transport // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016013 // syntrophin complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from mutant phenotype /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction /// 0051117 // ATPase binding // inferred from physical interaction 203517_at NM_006554 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006554.1 /DEF=Homo sapiens metaxin 2 (MTX2), mRNA. /FEA=mRNA /GEN=MTX2 /PROD=metaxin 2 /DB_XREF=gi:5729936 /UG=Hs.31584 metaxin 2 /FL=gb:AF053551.1 gb:NM_006554.1" NM_006554 metaxin 2 MTX2 10651 NM_001006635 /// NM_006554 /// NR_027850 /// XM_006712199 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 203518_at NM_000081 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000081.1 /DEF=Homo sapiens Chediak-Higashi syndrome 1 (CHS1), mRNA. /FEA=mRNA /GEN=CHS1 /PROD=beige protein homolog /DB_XREF=gi:4502838 /UG=Hs.36508 Chediak-Higashi syndrome 1 /FL=gb:U67615.1 gb:NM_000081.1" NM_000081 lysosomal trafficking regulator LYST 1130 NM_000081 /// NM_001005736 /// NR_102436 /// XM_005273027 /// XM_005273028 /// XM_005273029 /// XM_005273030 /// XM_006711731 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0002456 // T cell mediated immunity // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // inferred from sequence or structural similarity /// 0032438 // melanosome organization // inferred from sequence or structural similarity /// 0032510 // endosome to lysosome transport via multivesicular body sorting pathway // inferred from mutant phenotype /// 0032816 // positive regulation of natural killer cell activation // inferred from electronic annotation /// 0033299 // secretion of lysosomal enzymes // inferred from electronic annotation /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0042267 // natural killer cell mediated cytotoxicity // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0042832 // defense response to protozoan // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from mutant phenotype /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from sequence or structural similarity /// 0055091 // phospholipid homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203519_s_at NM_015542 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015542.1 /DEF=Homo sapiens regulator of nonsense transcripts 2; DKFZP434D222 protein (RENT2), mRNA. /FEA=mRNA /GEN=RENT2 /PROD=regulator of nonsense transcripts 2 /DB_XREF=gi:11693131 /UG=Hs.3862 regulator of nonsense transcripts 2; DKFZP434D222 protein /FL=gb:AF301013.1 gb:NM_015542.1 gb:AY013249.1 gb:AF318574.1" NM_015542 UPF2 regulator of nonsense transcripts homolog (yeast) UPF2 26019 NM_015542 /// NM_080599 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0035145 // exon-exon junction complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203520_s_at AW613549 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW613549 /FEA=EST /DB_XREF=gi:7318735 /DB_XREF=est:hh33g04.x1 /CLONE=IMAGE:2956950 /UG=Hs.48433 endocrine regulator /FL=gb:AF121141.1 gb:NM_014345.1 AW613549 zinc finger protein 318 ZNF318 24149 NM_014345 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203521_s_at NM_014345 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014345.1 /DEF=Homo sapiens endocrine regulator (HRIHFB2436), mRNA. /FEA=mRNA /GEN=HRIHFB2436 /PROD=endocrine regulator /DB_XREF=gi:7657183 /UG=Hs.48433 endocrine regulator /FL=gb:AF121141.1 gb:NM_014345.1" NM_014345 zinc finger protein 318 ZNF318 24149 NM_014345 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203522_at NM_005125 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005125.1 /DEF=Homo sapiens copper chaperone for superoxide dismutase (CCS), mRNA. /FEA=mRNA /GEN=CCS /PROD=copper chaperone for superoxide dismutase /DB_XREF=gi:4826664 /UG=Hs.5002 copper chaperone for superoxide dismutase /FL=gb:AF002210.1 gb:NM_005125.1" NM_005125 copper chaperone for superoxide dismutase CCS 9973 NM_005125 /// XR_247219 0006801 // superoxide metabolic process // traceable author statement /// 0015680 // intracellular copper ion transport // traceable author statement /// 0019430 // removal of superoxide radicals // not recorded /// 0030001 // metal ion transport // inferred from electronic annotation /// 0035434 // copper ion transmembrane transport // traceable author statement /// 0051353 // positive regulation of oxidoreductase activity // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // /// 0005829 // cytosol // traceable author statement 0004784 // superoxide dismutase activity // not recorded /// 0005375 // copper ion transmembrane transporter activity // traceable author statement /// 0005507 // copper ion binding // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // not recorded /// 0015035 // protein disulfide oxidoreductase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016532 // superoxide dismutase copper chaperone activity // /// 0046872 // metal ion binding // inferred from electronic annotation 203523_at NM_002339 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002339.1 /DEF=Homo sapiens lymphocyte-specific protein 1 (LSP1), mRNA. /FEA=mRNA /GEN=LSP1 /PROD=lymphocyte-specific protein 1 /DB_XREF=gi:10880978 /UG=Hs.56729 lymphocyte-specific protein 1 /FL=gb:NM_002339.1 gb:BC001785.1 gb:M33552.1" NM_002339 lymphocyte-specific protein 1 LSP1 4046 NM_001013253 /// NM_001013254 /// NM_001013255 /// NM_001242932 /// NM_001289005 /// NM_002339 /// XM_005252924 /// XM_005252926 /// XM_005252927 /// XM_006718232 0006928 // cellular component movement // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation 203524_s_at NM_021126 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021126.1 /DEF=Homo sapiens mercaptopyruvate sulfurtransferase (MPST), mRNA. /FEA=mRNA /GEN=MPST /PROD=mercaptopyruvate sulfurtransferase /DB_XREF=gi:13489090 /UG=Hs.74097 mercaptopyruvate sulfurtransferase /FL=gb:NM_021126.1" NM_021126 mercaptopyruvate sulfurtransferase MPST 4357 NM_001013436 /// NM_001013440 /// NM_001130517 /// NM_021126 /// NR_024038 /// XM_005261610 /// XM_006724253 0008152 // metabolic process // inferred from electronic annotation /// 0009440 // cyanate catabolic process // traceable author statement /// 0009636 // response to toxic substance // traceable author statement /// 0070814 // hydrogen sulfide biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004792 // thiosulfate sulfurtransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016784 // 3-mercaptopyruvate sulfurtransferase activity // inferred from electronic annotation 203525_s_at AI375486 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI375486 /FEA=EST /DB_XREF=gi:4175476 /DB_XREF=est:tc30f12.x1 /CLONE=IMAGE:2066159 /UG=Hs.75081 adenomatosis polyposis coli /FL=gb:M74088.1 gb:M73548.1 gb:NM_000038.1 AI375486 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 203526_s_at M74088 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M74088.1 /DEF=Human APC gene mRNA, complete cds. /FEA=mRNA /GEN=APC /DB_XREF=gi:182396 /UG=Hs.75081 adenomatosis polyposis coli /FL=gb:M74088.1 gb:M73548.1 gb:NM_000038.1" M74088 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 203527_s_at NM_000038 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000038.1 /DEF=Homo sapiens adenomatosis polyposis coli (APC), mRNA. /FEA=mRNA /GEN=APC /PROD=adenomatosis polyposis coli /DB_XREF=gi:4557318 /UG=Hs.75081 adenomatosis polyposis coli /FL=gb:M74088.1 gb:M73548.1 gb:NM_000038.1" NM_000038 adenomatous polyposis coli APC 324 NM_000038 /// NM_001127510 /// NM_001127511 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001822 // kidney development // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from direct assay /// 0007026 // negative regulation of microtubule depolymerization // inferred from mutant phenotype /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // inferred from mutant phenotype /// 0007155 // cell adhesion // non-traceable author statement /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009798 // axis specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030856 // regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from mutant phenotype /// 0032886 // regulation of microtubule-based process // inferred from mutant phenotype /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0042483 // negative regulation of odontogenesis // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0044336 // canonical Wnt signaling pathway involved in negative regulation of apoptotic process // inferred from electronic annotation /// 0044337 // canonical Wnt signaling pathway involved in positive regulation of apoptotic process // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045670 // regulation of osteoclast differentiation // inferred from electronic annotation /// 0045732 // positive regulation of protein catabolic process // inferred by curator /// 0045732 // positive regulation of protein catabolic process // inferred from genetic interaction /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051171 // regulation of nitrogen compound metabolic process // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // non-traceable author statement /// 0060041 // retina development in camera-type eye // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred by curator /// 0060070 // canonical Wnt signaling pathway // non-traceable author statement /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0070830 // tight junction assembly // non-traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030877 // beta-catenin destruction complex // inferred from direct assay /// 0031253 // cell projection membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0035371 // microtubule plus-end // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0019887 // protein kinase regulator activity // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from direct assay /// 0051010 // microtubule plus-end binding // inferred from direct assay 203528_at NM_006378 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006378.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (SEMA4D), mRNA. /FEA=mRNA /GEN=SEMA4D /PROD=sema domain, immunoglobulin domain (Ig),transmembrane domain (TM) and short cytoplasmic domain,(semaphorin) 4D /DB_XREF=gi:5454049 /UG=Hs.79089 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D /FL=gb:U60800.1 gb:NM_006378.1" NM_006378 "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D" SEMA4D 10507 NM_001142287 /// NM_006378 /// NM_182635 /// XM_005251654 /// XM_006716922 /// XM_006716923 /// XM_006716924 /// XM_006716925 /// XM_006716926 /// XM_006716927 /// XM_006716928 /// XM_006716929 /// XM_006716930 /// XM_006716931 /// XR_242561 /// XR_242562 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007162 // negative regulation of cell adhesion // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0010693 // negative regulation of alkaline phosphatase activity // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0031344 // regulation of cell projection organization // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032321 // positive regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043931 // ossification involved in bone maturation // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0048672 // positive regulation of collateral sprouting // inferred from mutant phenotype /// 0048814 // regulation of dendrite morphogenesis // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050732 // negative regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0070486 // leukocyte aggregation // inferred from mutant phenotype /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 0071526 // semaphorin-plexin signaling pathway // inferred from mutant phenotype /// 1900220 // semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from direct assay /// 0004888 // transmembrane signaling receptor activity // inferred from mutant phenotype /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030215 // semaphorin receptor binding // inferred from physical interaction /// 0030215 // semaphorin receptor binding // inferred from sequence or structural similarity 203529_at NM_016294 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016294.1 /DEF=Homo sapiens serinethreonine protein phosphatase catalytic subunit (LOC51723), mRNA. /FEA=mRNA /GEN=LOC51723 /PROD=serinethreonine protein phosphatase catalyticsubunit /DB_XREF=gi:7706488 /UG=Hs.80324 serinethreonine protein phosphatase catalytic subunit /FL=gb:AF035158.2 gb:NM_016294.1" NM_016294 "protein phosphatase 6, catalytic subunit" PPP6C 5537 NM_001123355 /// NM_001123369 /// NM_002721 /// XM_006717175 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203530_s_at NM_004604 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004604.1 /DEF=Homo sapiens syntaxin 4A (placental) (STX4A), mRNA. /FEA=mRNA /GEN=STX4A /PROD=syntaxin 4A (placental) /DB_XREF=gi:4759185 /UG=Hs.83734 syntaxin 4A (placental) /FL=gb:BC002436.1 gb:AF026007.1 gb:U07158.1 gb:NM_004604.1" NM_004604 syntaxin 4 STX4 6810 NM_001272095 /// NM_001272096 /// NM_004604 /// XM_005255521 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005773 // vacuole // traceable author statement /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031201 // SNARE complex // inferred from direct assay /// 0035749 // myelin sheath adaxonal region // inferred from electronic annotation /// 0042581 // specific granule // inferred from direct assay /// 0043219 // lateral loop // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000149 // SNARE binding // inferred from electronic annotation /// 0005484 // SNAP receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203531_at BF435809 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF435809 /FEA=EST /DB_XREF=gi:11448124 /DB_XREF=est:nab42a09.x1 /CLONE=IMAGE:3268504 /UG=Hs.101299 cullin 5 /FL=gb:AF327710.1 gb:AF017061.1 gb:NM_003478.1 BF435809 cullin 5 CUL5 8065 NM_003478 /// XM_005271682 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 203532_x_at AF017061 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF017061.1 /DEF=Homo sapiens vasopressin-activated calcium mobilizing putative receptor protein (VACM-1) mRNA, complete cds. /FEA=mRNA /GEN=VACM-1 /PROD=vasopressin-activated calcium mobilizingputative receptor protein /DB_XREF=gi:2394273 /UG=Hs.101299 cullin 5 /FL=gb:AF327710.1 gb:AF017061.1 gb:NM_003478.1" AF017061 cullin 5 CUL5 8065 NM_003478 /// XM_005271682 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 203533_s_at NM_003478 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003478.1 /DEF=Homo sapiens cullin 5 (CUL5), mRNA. /FEA=mRNA /GEN=CUL5 /PROD=Vasopressin-activated calcium-mobilizingreceptor-1 /DB_XREF=gi:4503166 /UG=Hs.101299 cullin 5 /FL=gb:AF327710.1 gb:AF017061.1 gb:NM_003478.1" NM_003478 cullin 5 CUL5 8065 NM_003478 /// XM_005271682 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0051480 // cytosolic calcium ion homeostasis // inferred from electronic annotation /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031466 // Cul5-RING ubiquitin ligase complex // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay 203534_at NM_014462 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014462.1 /DEF=Homo sapiens Lsm1 protein (LSM1), mRNA. /FEA=mRNA /GEN=LSM1 /PROD=Lsm1 protein /DB_XREF=gi:7657312 /UG=Hs.111783 Lsm1 protein /FL=gb:BC001767.1 gb:AF000177.1 gb:NM_014462.1" NM_014462 "LSM1, U6 small nuclear RNA associated" LSM1 27257 NM_014462 /// NR_045492 /// NR_045493 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement /// 0071044 // histone mRNA catabolic process // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203535_at NM_002965 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002965.2 /DEF=Homo sapiens S100 calcium-binding protein A9 (calgranulin B) (S100A9), mRNA. /FEA=mRNA /GEN=S100A9 /PROD=S100 calcium-binding protein A9 /DB_XREF=gi:9845520 /UG=Hs.112405 S100 calcium-binding protein A9 (calgranulin B) /FL=gb:M26311.1 gb:NM_002965.2" NM_002965 S100 calcium binding protein A9 S100A9 6280 NM_002965 0001816 // cytokine production // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002523 // leukocyte migration involved in inflammatory response // inferred from direct assay /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0006914 // autophagy // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030595 // leukocyte chemotaxis // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0032119 // sequestering of zinc ion // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032602 // chemokine production // traceable author statement /// 0042742 // defense response to bacterium // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation /// 0045113 // regulation of integrin biosynthetic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from direct assay /// 0050832 // defense response to fungus // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0070488 // neutrophil aggregation // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004871 // signal transducer activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0035662 // Toll-like receptor 4 binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050544 // arachidonic acid binding // traceable author statement /// 0050786 // RAGE receptor binding // traceable author statement 203536_s_at NM_004804 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004804.1 /DEF=Homo sapiens WD40 protein Ciao1 (CIAO1), mRNA. /FEA=mRNA /GEN=CIAO1 /PROD=WD40 protein Ciao1 /DB_XREF=gi:4757987 /UG=Hs.12109 WD40 protein Ciao1 /FL=gb:BC001395.1 gb:U63810.1 gb:NM_004804.1" NM_004804 cytosolic iron-sulfur assembly component 1 CIAO1 9391 NM_004804 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016226 // iron-sulfur cluster assembly // inferred from genetic interaction /// 0044281 // small molecule metabolic process // traceable author statement 0071817 // MMXD complex // inferred from direct assay /// 0097361 // CIA complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203537_at NM_002767 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002767.1 /DEF=Homo sapiens phosphoribosyl pyrophosphate synthetase-associated protein 2 (PRPSAP2), mRNA. /FEA=mRNA /GEN=PRPSAP2 /PROD=phosphoribosyl pyrophosphatesynthetase-associated protein 2 /DB_XREF=gi:4506132 /UG=Hs.13339 phosphoribosyl pyrophosphate synthetase-associated protein 2 /FL=gb:AB007851.1 gb:NM_002767.1" NM_002767 phosphoribosyl pyrophosphate synthetase-associated protein 2 PRPSAP2 5636 NM_001243936 /// NM_001243940 /// NM_001243941 /// NM_001243942 /// NM_002767 /// XM_005256724 /// XM_005256725 /// XM_005256726 /// XM_005256727 /// XM_005256729 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0060348 // bone development // inferred from electronic annotation 0002189 // ribose phosphate diphosphokinase complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004749 // ribose phosphate diphosphokinase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement 203538_at NM_001745 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001745.1 /DEF=Homo sapiens calcium modulating ligand (CAMLG), mRNA. /FEA=mRNA /GEN=CAMLG /PROD=calcium modulating ligand /DB_XREF=gi:4502558 /UG=Hs.13572 calcium modulating ligand /FL=gb:NM_001745.1 gb:U18242.1" NM_001745 calcium modulating ligand CAMLG 819 NM_001745 0001881 // receptor recycling // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050839 // cell adhesion molecule binding // inferred from electronic annotation 203539_s_at J04569 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:J04569.1 /DEF=Human glial fibrillary acidic protein (GFAP) mRNA, complete cds. /FEA=mRNA /GEN=GFAP /DB_XREF=gi:183074 /UG=Hs.1447 glial fibrillary acidic protein /FL=gb:J04569.1 gb:NM_002055.1" J04569 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203540_at NM_002055 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002055.1 /DEF=Homo sapiens glial fibrillary acidic protein (GFAP), mRNA. /FEA=mRNA /GEN=GFAP /PROD=glial fibrillary acidic protein /DB_XREF=gi:4503978 /UG=Hs.1447 glial fibrillary acidic protein /FL=gb:J04569.1 gb:NM_002055.1" NM_002055 glial fibrillary acidic protein GFAP 2670 NM_001131019 /// NM_001242376 /// NM_002055 0009611 // response to wounding // inferred from electronic annotation /// 0010625 // positive regulation of Schwann cell proliferation // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0014002 // astrocyte development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0031102 // neuron projection regeneration // inferred from electronic annotation /// 0045103 // intermediate filament-based process // inferred from electronic annotation /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0051580 // regulation of neurotransmitter uptake // inferred from electronic annotation /// 0060020 // Bergmann glial cell differentiation // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0097449 // astrocyte projection // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation 203541_s_at BF438302 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF438302 /FEA=EST /DB_XREF=gi:11450819 /DB_XREF=est:7q07f04.x1 /CLONE=IMAGE:3676950 /UG=Hs.150557 basic transcription element binding protein 1 /FL=gb:NM_001206.1 gb:D31716.1 BF438302 Kruppel-like factor 9 KLF9 687 NM_001206 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203542_s_at AI690205 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI690205 /FEA=EST /DB_XREF=gi:4901499 /DB_XREF=est:tx33d02.x1 /CLONE=IMAGE:2271363 /UG=Hs.150557 basic transcription element binding protein 1 /FL=gb:NM_001206.1 gb:D31716.1 AI690205 Kruppel-like factor 9 KLF9 687 NM_001206 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203543_s_at NM_001206 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001206.1 /DEF=Homo sapiens basic transcription element binding protein 1 (BTEB1), mRNA. /FEA=mRNA /GEN=BTEB1 /PROD=basic transcription element binding protein 1 /DB_XREF=gi:4557374 /UG=Hs.150557 basic transcription element binding protein 1 /FL=gb:NM_001206.1 gb:D31716.1" NM_001206 Kruppel-like factor 9 KLF9 687 NM_001206 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0050847 // progesterone receptor signaling pathway // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203544_s_at NM_003473 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003473.1 /DEF=Homo sapiens signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 (STAM), mRNA. /FEA=mRNA /GEN=STAM /PROD=signal transducing adaptor molecule (SH3 domainand ITAM motif) 1 /DB_XREF=gi:4507248 /UG=Hs.153487 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 /FL=gb:U43899.1 gb:NM_003473.1" NM_003473 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 STAM 8027 NM_003473 /// NR_037774 /// XM_005252603 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosomal transport // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203545_at NM_024079 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024079.1 /DEF=Homo sapiens hypothetical protein MGC2840 similar to a putative glucosyltransferase (MGC2840), mRNA. /FEA=mRNA /GEN=MGC2840 /PROD=hypothetical protein MGC2840 similar to aputative glucosyltransferase /DB_XREF=gi:13129069 /UG=Hs.155356 hypothetical protein MGC2840 similar to a putative glucosyltransferase /FL=gb:BC001133.1 gb:NM_024079.1" NM_024079 "ALG8, alpha-1,3-glucosyltransferase" ALG8 79053 NM_001007027 /// NM_001007028 /// NM_024079 /// XM_005274247 /// XR_428923 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // inferred from mutant phenotype /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from mutant phenotype 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0000033 // alpha-1,3-mannosyltransferase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation" 203546_at NM_014652 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014652.1 /DEF=Homo sapiens KIAA0724 gene product (KIAA0724), mRNA. /FEA=mRNA /GEN=KIAA0724 /PROD=KIAA0724 gene product /DB_XREF=gi:7662265 /UG=Hs.158497 KIAA0724 gene product /FL=gb:AB018267.1 gb:NM_014652.1 gb:AF267987.1" NM_014652 importin 13 IPO13 9670 NM_014652 /// XM_003846624 0006606 // protein import into nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // inferred from electronic annotation 203547_at U47924 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:U47924 /DEF=Human chromosome 12p13 sequence /FEA=mRNA_6 /DB_XREF=gi:1633547 /UG=Hs.17483 CD4 antigen (p55) /FL=gb:NM_000616.1 gb:M12807.1 U47924 CD4 molecule CD4 920 NM_000616 /// NM_001195014 /// NM_001195015 /// NM_001195016 /// NM_001195017 /// NR_036545 0001816 // cytokine production // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0006948 // induction by virus of host cell-cell fusion // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from direct assay /// 0030260 // entry into host cell // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032507 // maintenance of protein location in cell // inferred from direct assay /// 0042110 // T cell activation // inferred from electronic annotation /// 0045058 // T cell selection // inferred from direct assay /// 0045086 // positive regulation of interleukin-2 biosynthetic process // non-traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045234 // protein palmitoleylation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0050690 // regulation of defense response to virus by virus // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050863 // regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from electronic annotation 0005769 // early endosome // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // non-traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation 0001948 // glycoprotein binding // inferred from physical interaction /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0015026 // coreceptor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042289 // MHC class II protein binding // non-traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 203548_s_at BF672975 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF672975 /FEA=EST /DB_XREF=gi:11946870 /DB_XREF=est:602152854F1 /CLONE=IMAGE:4294021 /UG=Hs.180878 lipoprotein lipase /FL=gb:M15856.1 gb:NM_000237.1 BF672975 lipoprotein lipase LPL 4023 NM_000237 "0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred by curator /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0006633 // fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006644 // phospholipid metabolic process // inferred from sequence or structural similarity /// 0007603 // phototransduction, visible light // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010886 // positive regulation of cholesterol storage // inferred from mutant phenotype /// 0010890 // positive regulation of sequestering of triglyceride // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // inferred from sequence or structural similarity /// 0034371 // chylomicron remodeling // inferred by curator /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070328 // triglyceride homeostasis // inferred from genetic interaction" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0042627 // chylomicron // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004465 // lipoprotein lipase activity // inferred from direct assay /// 0004465 // lipoprotein lipase activity // inferred from sequence or structural similarity /// 0004620 // phospholipase activity // inferred from sequence or structural similarity /// 0004806 // triglyceride lipase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017129 // triglyceride binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction 203549_s_at NM_000237 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000237.1 /DEF=Homo sapiens lipoprotein lipase (LPL), mRNA. /FEA=mRNA /GEN=LPL /PROD=lipoprotein lipase precursor /DB_XREF=gi:4557726 /UG=Hs.180878 lipoprotein lipase /FL=gb:M15856.1 gb:NM_000237.1" NM_000237 lipoprotein lipase LPL 4023 NM_000237 "0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred by curator /// 0006633 // fatty acid biosynthetic process // inferred from direct assay /// 0006633 // fatty acid biosynthetic process // inferred from sequence or structural similarity /// 0006641 // triglyceride metabolic process // inferred from sequence or structural similarity /// 0006644 // phospholipid metabolic process // inferred from sequence or structural similarity /// 0007603 // phototransduction, visible light // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010886 // positive regulation of cholesterol storage // inferred from mutant phenotype /// 0010890 // positive regulation of sequestering of triglyceride // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // inferred from direct assay /// 0019433 // triglyceride catabolic process // inferred from sequence or structural similarity /// 0034371 // chylomicron remodeling // inferred by curator /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from sequence or structural similarity /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070328 // triglyceride homeostasis // inferred from genetic interaction" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0042627 // chylomicron // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004465 // lipoprotein lipase activity // inferred from direct assay /// 0004465 // lipoprotein lipase activity // inferred from sequence or structural similarity /// 0004620 // phospholipase activity // inferred from sequence or structural similarity /// 0004806 // triglyceride lipase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017129 // triglyceride binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction 203550_s_at NM_006589 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006589.1 /DEF=Homo sapiens chromosome 1 open reading frame 2 (C1ORF2), mRNA. /FEA=mRNA /GEN=C1ORF2 /PROD=chromosome 1 open reading frame 2 /DB_XREF=gi:5729751 /UG=Hs.19554 chromosome 1 open reading frame 2 /FL=gb:NM_006589.1" NM_006589 "family with sequence similarity 189, member B" FAM189B 10712 NM_001267608 /// NM_006589 /// NM_198264 /// XM_005244845 /// XM_005244847 /// XM_005244848 /// XM_005276738 /// XM_005276740 /// XM_005276741 /// XM_006711126 /// XM_006711127 /// XM_006726209 /// XM_006726210 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0050699 // WW domain binding // inferred from physical interaction 203551_s_at NM_004375 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004375.1 /DEF=Homo sapiens COX11 (yeast) homolog, cytochrome c oxidase assembly protein (COX11), mRNA. /FEA=mRNA /GEN=COX11 /PROD=COX11 (yeast) homolog, cytochrome c oxidaseassembly protein /DB_XREF=gi:4758033 /UG=Hs.241515 COX11 (yeast) homolog, cytochrome c oxidase assembly protein /FL=gb:AF044321.1 gb:NM_004375.1" NM_004375 cytochrome c oxidase assembly homolog 11 (yeast) COX11 1353 NM_001162861 /// NM_001162862 /// NM_004375 /// NR_027941 /// NR_027942 /// XM_006721704 /// XM_006721705 0007585 // respiratory gaseous exchange // traceable author statement /// 0008535 // respiratory chain complex IV assembly // traceable author statement /// 0033132 // negative regulation of glucokinase activity // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement 203552_at AW298170 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW298170 /FEA=EST /DB_XREF=gi:6704806 /DB_XREF=est:UI-H-BW0-ajt-a-06-0-UI.s1 /CLONE=IMAGE:2732819 /UG=Hs.246970 mitogen-activated protein kinase kinase kinase kinase 5 /FL=gb:U77129.1 gb:NM_006575.1 AW298170 mitogen-activated protein kinase kinase kinase kinase 5 MAP4K5 11183 NM_006575 /// NM_198794 /// XM_006720013 /// XM_006720014 0000165 // MAPK cascade // /// 0000185 // activation of MAPKKK activity // /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203553_s_at NM_006575 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006575.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5), mRNA. /FEA=mRNA /GEN=MAP4K5 /PROD=mitogen-activated protein kinase kinase kinasekinase /DB_XREF=gi:5729890 /UG=Hs.246970 mitogen-activated protein kinase kinase kinase kinase 5 /FL=gb:U77129.1 gb:NM_006575.1" NM_006575 mitogen-activated protein kinase kinase kinase kinase 5 MAP4K5 11183 NM_006575 /// NM_198794 /// XM_006720013 /// XM_006720014 0000165 // MAPK cascade // /// 0000185 // activation of MAPKKK activity // /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008349 // MAP kinase kinase kinase kinase activity // /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203554_x_at NM_004219 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004219.2 /DEF=Homo sapiens pituitary tumor-transforming 1 (PTTG1), mRNA. /FEA=mRNA /GEN=PTTG1 /PROD=pituitary tumor-transforming protein 1 /DB_XREF=gi:11038651 /UG=Hs.252587 pituitary tumor-transforming 1 /FL=gb:NM_004219.2 gb:AF095287.1 gb:AF062649.1 gb:AF075242.1" NM_004219 pituitary tumor-transforming 1 PTTG1 9232 NM_001282382 /// NM_001282383 /// NM_004219 "0000278 // mitotic cell cycle // traceable author statement /// 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0010951 // negative regulation of endopeptidase activity // non-traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 203555_at NM_014369 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014369.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18), mRNA. /FEA=mRNA /GEN=PTPN18 /PROD=protein tyrosine phosphatase, non-receptor type18 (brain-derived) /DB_XREF=gi:7657483 /UG=Hs.278597 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) /FL=gb:NM_014369.1" NM_014369 "protein tyrosine phosphatase, non-receptor type 18 (brain-derived)" PTPN18 26469 NM_001142370 /// NM_014369 /// XM_006712415 /// XM_006712416 /// XM_006712417 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 203556_at NM_014943 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014943.1 /DEF=Homo sapiens KIAA0854 protein (KIAA0854), mRNA. /FEA=mRNA /GEN=KIAA0854 /PROD=KIAA0854 protein /DB_XREF=gi:7662341 /UG=Hs.30209 KIAA0854 protein /FL=gb:AB020661.1 gb:NM_014943.1" NM_014943 zinc fingers and homeoboxes 2 ZHX2 22882 NM_014943 /// XM_005250836 /// XM_005250837 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006402 // mRNA catabolic process // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 203557_s_at NM_000281 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000281.1 /DEF=Homo sapiens 6-pyruvoyl-tetrahydropterin synthasedimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) (PCBD), mRNA. /FEA=mRNA /GEN=PCBD /PROD=pterin-4 alpha-carbinolamine dehydrataseprecursor /DB_XREF=gi:4557830 /UG=Hs.3192 6-pyruvoyl-tetrahydropterin synthasedimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) /FL=gb:NM_000281.1 gb:AF082858.1 gb:L41559.1" NM_000281 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha PCBD1 5092 NM_000281 /// NM_001289797 /// XM_005269877 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043496 // regulation of protein homodimerization activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0004505 // phenylalanine 4-monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008124 // 4-alpha-hydroxytetrahydrobiopterin dehydratase activity // not recorded /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203558_at NM_014780 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014780.1 /DEF=Homo sapiens KIAA0076 gene product (KIAA0076), mRNA. /FEA=mRNA /GEN=KIAA0076 /PROD=KIAA0076 gene product /DB_XREF=gi:7661893 /UG=Hs.51039 KIAA0076 gene product /FL=gb:D38548.1 gb:NM_014780.1" NM_014780 cullin 7 CUL7 9820 NM_001168370 /// NM_014780 /// XM_005249503 /// XM_006715285 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000281 // mitotic cytokinesis // inferred from mutant phenotype /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001890 // placenta development // inferred from direct assay /// 0006508 // proteolysis // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007030 // Golgi organization // inferred from sequence or structural similarity /// 0007088 // regulation of mitosis // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050775 // positive regulation of dendrite morphogenesis // inferred from genetic interaction /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005680 // anaphase-promoting complex // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation /// 0031467 // Cul7-RING ubiquitin ligase complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 1990393 // 3M complex // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 203559_s_at NM_001091 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001091.1 /DEF=Homo sapiens amiloride binding protein 1 (amine oxidase (copper-containing)) (ABP1), mRNA. /FEA=mRNA /GEN=ABP1 /PROD=amiloride binding protein 1 precursor /DB_XREF=gi:4501850 /UG=Hs.75741 amiloride binding protein 1 (amine oxidase (copper-containing)) /FL=gb:M55602.1 gb:NM_001091.1 gb:U11862.1" NM_001091 "amine oxidase, copper containing 1" AOC1 26 NM_001091 /// NM_001272072 /// XM_005249967 /// XM_006715918 0009308 // amine metabolic process // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0035874 // cellular response to copper ion starvation // inferred from direct assay /// 0042493 // response to drug // inferred from direct assay /// 0046677 // response to antibiotic // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071280 // cellular response to copper ion // inferred from direct assay /// 0071420 // cellular response to histamine // inferred from direct assay /// 0071504 // cellular response to heparin // traceable author statement /// 0097185 // cellular response to azide // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005777 // peroxisome // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004872 // receptor activity // inferred from direct assay /// 0005261 // cation channel activity // inferred from direct assay /// 0005272 // sodium channel activity // traceable author statement /// 0005507 // copper ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0008131 // primary amine oxidase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048038 // quinone binding // inferred from direct assay /// 0052597 // diamine oxidase activity // inferred from direct assay /// 0052598 // histamine oxidase activity // inferred from electronic annotation /// 0052599 // methylputrescine oxidase activity // inferred from electronic annotation /// 0052600 // propane-1,3-diamine oxidase activity // inferred from electronic annotation" 203560_at NM_003878 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003878.1 /DEF=Homo sapiens gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (GGH), mRNA. /FEA=mRNA /GEN=GGH /PROD=gamma-glutamyl hydrolase (conjugase,folylpolygammaglutamyl hydrolase) precursor /DB_XREF=gi:4503986 /UG=Hs.78619 gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) /FL=gb:U55206.1 gb:NM_003878.1" NM_003878 "gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)" GGH 8836 NM_003878 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008238 // exopeptidase activity // traceable author statement /// 0008242 // omega peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034722 // gamma-glutamyl-peptidase activity // inferred from direct assay 203561_at NM_021642 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021642.1 /DEF=Homo sapiens Fc fragment of IgG, low affinity IIa, receptor for (CD32) (FCGR2A), mRNA. /FEA=mRNA /GEN=FCGR2A /PROD=Fc fragment of IgG, low affinity IIa, receptorfor (CD32) /DB_XREF=gi:11056051 /UG=Hs.78864 Fc fragment of IgG, low affinity IIa, receptor for (CD32) /FL=gb:NM_021642.1 gb:M31932.1 gb:J03619.1 gb:M28697.1" NM_021642 "Fc fragment of IgG, low affinity IIa, receptor (CD32)" FCGR2A 2212 NM_001136219 /// NM_021642 /// XM_005244960 0002376 // immune system process // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019864 // IgG binding // inferred from electronic annotation 203562_at NM_005103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005103.2 /DEF=Homo sapiens fasciculation and elongation protein zeta 1 (zygin I) (FEZ1), transcript variant 1, mRNA. /FEA=mRNA /GEN=FEZ1 /PROD=zygin 1, isoform 1 /DB_XREF=gi:12025681 /UG=Hs.79226 fasciculation and elongation protein zeta 1 (zygin I) /FL=gb:NM_005103.2 gb:U69139.1 gb:U60060.1" NM_005103 fasciculation and elongation protein zeta 1 (zygin I) FEZ1 9638 NM_005103 /// NM_022549 /// XM_005271734 /// XM_005271735 0006810 // transport // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0051654 // establishment of mitochondrion localization // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from electronic annotation 203563_at NM_021638 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021638.1 /DEF=Homo sapiens actin filament associated protein (AFAP), mRNA. /FEA=mRNA /GEN=AFAP /PROD=actin filament associated protein /DB_XREF=gi:11056013 /UG=Hs.80306 actin filament associated protein /FL=gb:AF188700.1 gb:NM_021638.1" NM_021638 actin filament associated protein 1 AFAP1 60312 NM_001134647 /// NM_021638 /// NM_198595 /// XM_006713908 /// XM_006713909 /// XM_006713910 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203564_at NM_004629 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004629.1 /DEF=Homo sapiens Fanconi anemia, complementation group G (FANCG), mRNA. /FEA=mRNA /GEN=FANCG /PROD=X-ray repair complementing defective repair inChinese hamster cells 9 /DB_XREF=gi:4759335 /UG=Hs.8047 Fanconi anemia, complementation group G /FL=gb:BC000032.1 gb:U70310.1 gb:NM_004629.1" NM_004629 "Fanconi anemia, complementation group G" FANCG 2189 NM_004629 0000075 // cell cycle checkpoint // traceable author statement /// 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0007286 // spermatid development // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0003684 // damaged DNA binding // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203565_s_at NM_002431 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002431.1 /DEF=Homo sapiens menage a trois 1 (CAK assembly factor) (MNAT1), mRNA. /FEA=mRNA /GEN=MNAT1 /PROD=menage a trois 1 (CAK assembly factor) /DB_XREF=gi:4505224 /UG=Hs.82380 menage a trois 1 (CAK assembly factor) /FL=gb:BC000820.1 gb:NM_002431.1" NM_002431 MNAT CDK-activating kinase assembly factor 1 MNAT1 4331 NM_001177963 /// NM_002431 /// XM_005267687 /// XM_005267688 "0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007512 // adult heart development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0021591 // ventricular system development // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0044236 // multicellular organismal metabolic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 203566_s_at NM_000645 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000645.1 /DEF=Homo sapiens amylo-1,6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) (AGL), transcript variant 5, mRNA. /FEA=mRNA /GEN=AGL /PROD=amylo-1,6-glucosidase,4-alpha-glucanotransferase isoform 2 /DB_XREF=gi:4557282 /UG=Hs.904 amylo-1,6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) /FL=gb:M85168.1 gb:NM_000645.1" NM_000645 "amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" AGL 178 NM_000028 /// NM_000642 /// NM_000643 /// NM_000644 /// NM_000645 /// NM_000646 /// XM_005270557 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // not recorded /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016234 // inclusion body // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0043033 // isoamylase complex // traceable author statement "0003824 // catalytic activity // inferred from electronic annotation /// 0004133 // glycogen debranching enzyme activity // traceable author statement /// 0004134 // 4-alpha-glucanotransferase activity // not recorded /// 0004135 // amylo-alpha-1,6-glucosidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0030247 // polysaccharide binding // inferred from electronic annotation /// 0031593 // polyubiquitin binding // inferred from electronic annotation" 203567_s_at AU157590 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU157590 /FEA=EST /DB_XREF=gi:11019111 /DB_XREF=est:AU157590 /CLONE=PLACE1008438 /UG=Hs.59545 ring finger protein 15 /FL=gb:U90547.1 gb:NM_006355.1 AU157590 tripartite motif containing 38 TRIM38 10475 NM_006355 /// XM_005248799 /// XM_005248800 /// XR_241880 0007165 // signal transduction // inferred from mutant phenotype /// 0032648 // regulation of interferon-beta production // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from electronic annotation /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203568_s_at NM_006355 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006355.1 /DEF=Homo sapiens ring finger protein 15 (RNF15), mRNA. /FEA=mRNA /GEN=RNF15 /PROD=ring finger protein 15 /DB_XREF=gi:5454013 /UG=Hs.59545 ring finger protein 15 /FL=gb:U90547.1 gb:NM_006355.1" NM_006355 tripartite motif containing 38 TRIM38 10475 NM_006355 /// XM_005248799 /// XM_005248800 /// XR_241880 0007165 // signal transduction // inferred from mutant phenotype /// 0032648 // regulation of interferon-beta production // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from electronic annotation /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203569_s_at NM_003611 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003611.1 /DEF=Homo sapiens chromosome X open reading frame 5 (CXORF5), mRNA. /FEA=mRNA /GEN=CXORF5 /PROD=chromosome X open reading frame 5 /DB_XREF=gi:4503178 /UG=Hs.6483 oral-facial-digital syndrome 1 gene /FL=gb:NM_003611.1" NM_003611 oral-facial-digital syndrome 1 OFD1 8481 NM_003611 /// XM_005274599 /// XM_005274600 /// XM_005274601 /// XM_005274602 /// XM_005274603 /// XM_005274604 /// XM_005274605 /// XM_005274606 /// XM_005274607 /// XM_005274609 /// XR_247288 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006952 // defense response // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from sequence or structural similarity /// 0007099 // centriole replication // inferred from sequence or structural similarity /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from sequence or structural similarity /// 0060287 // epithelial cilium movement involved in determination of left/right asymmetry // inferred from sequence or structural similarity /// 0090307 // spindle assembly involved in mitosis // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from direct assay /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0043014 // alpha-tubulin binding // inferred from sequence or structural similarity /// 0043015 // gamma-tubulin binding // inferred from sequence or structural similarity 203570_at NM_005576 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005576.1 /DEF=Homo sapiens lysyl oxidase-like 1 (LOXL1), mRNA. /FEA=mRNA /GEN=LOXL1 /PROD=lysyl oxidase-like 1 /DB_XREF=gi:5031882 /UG=Hs.65436 lysyl oxidase-like 1 /FL=gb:L21186.1 gb:NM_005576.1" NM_005576 lysyl oxidase-like 1 LOXL1 4016 NM_005576 0018277 // protein deamination // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay "0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203571_s_at NM_006829 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006829.1 /DEF=Homo sapiens adipose specific 2 (APM2), mRNA. /FEA=mRNA /GEN=APM2 /PROD=adipose specific 2 /DB_XREF=gi:5802975 /UG=Hs.74120 adipose specific 2 /FL=gb:BC004471.1 gb:NM_006829.1 gb:D45370.1" NM_006829 adipogenesis regulatory factor ADIRF 10974 NM_006829 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071478 // cellular response to radiation // inferred from direct assay /// 0072719 // cellular response to cisplatin // inferred from direct assay /// 2001023 // regulation of response to drug // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 203572_s_at NM_005641 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005641.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, E, 7085kD (TAF2E), mRNA. /FEA=mRNA /GEN=TAF2E /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, E, 7085kD /DB_XREF=gi:5032146 /UG=Hs.78865 TATA box binding protein (TBP)-associated factor, RNA polymerase II, E, 7085kD /FL=gb:NM_005641.1 gb:L25444.1" NM_005641 "TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa" TAF6 6878 NM_001190415 /// NM_005641 /// NM_139122 /// NM_139123 /// NM_139315 /// NR_033792 /// XM_006716100 /// XM_006716101 /// XM_006716102 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203573_s_at NM_004581 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004581.1 /DEF=Homo sapiens Rab geranylgeranyltransferase, alpha subunit (RABGGTA), mRNA. /FEA=mRNA /GEN=RABGGTA /PROD=Rab geranylgeranyltransferase, alpha subunit /DB_XREF=gi:4759015 /UG=Hs.78920 Rab geranylgeranyltransferase, alpha subunit /FL=gb:NM_004581.1" NM_004581 "Rab geranylgeranyltransferase, alpha subunit" RABGGTA 5875 NM_004581 /// NM_182836 /// XM_005267959 /// XM_005267960 0006464 // cellular protein modification process // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0018342 // protein prenylation // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from sequence or structural similarity 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from sequence or structural similarity 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004663 // Rab geranylgeranyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 203574_at NM_005384 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005384.1 /DEF=Homo sapiens nuclear factor, interleukin 3 regulated (NFIL3), mRNA. /FEA=mRNA /GEN=NFIL3 /PROD=nuclear factor, interleukin 3 regulated /DB_XREF=gi:4885516 /UG=Hs.79334 nuclear factor, interleukin 3 regulated /FL=gb:U26173.1 gb:NM_005384.1" NM_005384 "nuclear factor, interleukin 3 regulated" NFIL3 4783 NM_001289999 /// NM_001290000 /// NM_005384 /// XM_005251999 /// XM_005252000 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203575_at NM_001896 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001896.1 /DEF=Homo sapiens casein kinase 2, alpha prime polypeptide (CSNK2A2), mRNA. /FEA=mRNA /GEN=CSNK2A2 /PROD=casein kinase 2, alpha prime polypeptide /DB_XREF=gi:4503096 /UG=Hs.82201 casein kinase 2, alpha prime polypeptide /FL=gb:M55268.1 gb:NM_001896.1" NM_001896 "casein kinase 2, alpha prime polypeptide" CSNK2A2 1459 NM_001896 /// XM_005255799 /// XM_005255800 /// XM_005255801 "0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071174 // mitotic spindle checkpoint // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031519 // PcG protein complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction" 203576_at NM_001190 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001190.1 /DEF=Homo sapiens branched chain aminotransferase 2, mitochondrial (BCAT2), mRNA. /FEA=mRNA /GEN=BCAT2 /PROD=branched chain aminotransferase 2,mitochondrial /DB_XREF=gi:4502374 /UG=Hs.101408 branched chain aminotransferase 2, mitochondrial /FL=gb:BC001900.1 gb:BC004243.1 gb:U62739.1 gb:U68418.1 gb:NM_001190.1" NM_001190 "branched chain amino-acid transaminase 2, mitochondrial" BCAT2 587 NM_001164773 /// NM_001190 /// NM_001284325 /// NR_028451 0006549 // isoleucine metabolic process // inferred from electronic annotation /// 0006550 // isoleucine catabolic process // inferred from electronic annotation /// 0006551 // leucine metabolic process // inferred from electronic annotation /// 0006573 // valine metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009081 // branched-chain amino acid metabolic process // inferred from electronic annotation /// 0009082 // branched-chain amino acid biosynthetic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0010817 // regulation of hormone levels // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004084 // branched-chain-amino-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0052654 // L-leucine transaminase activity // inferred from electronic annotation /// 0052655 // L-valine transaminase activity // inferred from electronic annotation /// 0052656 // L-isoleucine transaminase activity // inferred from electronic annotation 203577_at NM_001517 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001517.1 /DEF=Homo sapiens general transcription factor IIH, polypeptide 4 (52kD subunit) (GTF2H4), mRNA. /FEA=mRNA /GEN=GTF2H4 /PROD=general transcription factor IIH, polypeptide 4(52kD subunit) /DB_XREF=gi:4504200 /UG=Hs.102910 general transcription factor IIH, polypeptide 4 (52kD subunit) /FL=gb:BC004935.1 gb:NM_001517.1" NM_001517 "general transcription factor IIH, polypeptide 4, 52kDa" GTF2H4 2968 NM_001517 "0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0050434 // positive regulation of viral transcription // traceable author statement" 0000439 // core TFIIH complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation 203578_s_at BG230586 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG230586 /FEA=EST /DB_XREF=gi:12725619 /DB_XREF=est:naf40g01.x1 /CLONE=IMAGE:4143552 /UG=Hs.10315 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 /FL=gb:D87432.1 gb:NM_003983.1" BG230586 "solute carrier family 7 (amino acid transporter light chain, y+L system), member 6" SLC7A6 9057 NM_001076785 /// NM_003983 /// XR_243433 /// XR_429735 /// XR_429736 /// XR_429737 /// XR_429738 /// XR_429739 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 203579_s_at AI660619 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI660619 /FEA=EST /DB_XREF=gi:4764202 /DB_XREF=est:wf21h04.x1 /CLONE=IMAGE:2351287 /UG=Hs.10315 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 /FL=gb:D87432.1 gb:NM_003983.1" AI660619 "solute carrier family 7 (amino acid transporter light chain, y+L system), member 6" SLC7A6 9057 NM_001076785 /// NM_003983 /// XR_243433 /// XR_429735 /// XR_429736 /// XR_429737 /// XR_429738 /// XR_429739 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 203580_s_at NM_003983 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003983.1 /DEF=Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), mRNA. /FEA=mRNA /GEN=SLC7A6 /PROD=solute carrier family 7 (cationic amino acidtransporter, y+ system), member 6 /DB_XREF=gi:4507052 /UG=Hs.10315 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 /FL=gb:D87432.1 gb:NM_003983.1" NM_003983 "solute carrier family 7 (amino acid transporter light chain, y+L system), member 6" SLC7A6 9057 NM_001076785 /// NM_003983 /// XR_243433 /// XR_429735 /// XR_429736 /// XR_429737 /// XR_429738 /// XR_429739 0003333 // amino acid transmembrane transport // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006520 // cellular amino acid metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation 203581_at BC002438 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002438.1 /DEF=Homo sapiens, RAB4, member RAS oncogene family, clone MGC:1486, mRNA, complete cds. /FEA=mRNA /PROD=RAB4, member RAS oncogene family /DB_XREF=gi:12803248 /UG=Hs.119007 RAB4, member RAS oncogene family /FL=gb:BC002438.1 gb:BC004309.1 gb:NM_004578.1 gb:M28211.1" BC002438 "RAB4A, member RAS oncogene family /// S-phase response (cyclin related)" RAB4A /// SPHAR 5867 /// 10638 NM_001271998 /// NM_004578 /// NM_006542 /// NR_073545 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 203582_s_at NM_004578 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004578.1 /DEF=Homo sapiens RAB4, member RAS oncogene family (RAB4), mRNA. /FEA=mRNA /GEN=RAB4 /PROD=RAB4, member RAS oncogene family /DB_XREF=gi:4759001 /UG=Hs.119007 RAB4, member RAS oncogene family /FL=gb:BC002438.1 gb:BC004309.1 gb:NM_004578.1 gb:M28211.1" NM_004578 "RAB4A, member RAS oncogene family /// S-phase response (cyclin related)" RAB4A /// SPHAR 5867 /// 10638 NM_001271998 /// NM_004578 /// NM_006542 /// NR_073545 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay 203583_at NM_014044 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014044.1 /DEF=Homo sapiens DKFZP564G0222 protein (DKFZP564G0222), mRNA. /FEA=mRNA /GEN=DKFZP564G0222 /PROD=DKFZP564G0222 protein /DB_XREF=gi:7661609 /UG=Hs.13370 DKFZP564G0222 protein /FL=gb:AF077038.1 gb:AL080115.1 gb:NM_014044.1" NM_014044 unc-50 homolog (C. elegans) UNC50 25972 NM_014044 /// XM_005263913 /// XM_006712403 /// XM_006712404 0006810 // transport // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation 203584_at NM_014673 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014673.1 /DEF=Homo sapiens KIAA0103 gene product (KIAA0103), mRNA. /FEA=mRNA /GEN=KIAA0103 /PROD=KIAA0103 gene product /DB_XREF=gi:7661909 /UG=Hs.154387 KIAA0103 gene product /FL=gb:D14659.1 gb:NM_014673.1" NM_014673 ER membrane protein complex subunit 2 EMC2 9694 NM_014673 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203585_at NM_007150 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007150.1 /DEF=Homo sapiens zinc finger protein 185 (LIM domain) (ZNF185), mRNA. /FEA=mRNA /GEN=ZNF185 /PROD=zinc finger protein 185 (LIM domain) /DB_XREF=gi:6005971 /UG=Hs.16622 zinc finger protein 185 (LIM domain) /FL=gb:NM_007150.1" NM_007150 zinc finger protein 185 (LIM domain) ZNF185 7739 NM_001178106 /// NM_001178107 /// NM_001178108 /// NM_001178109 /// NM_001178110 /// NM_001178113 /// NM_001178114 /// NM_001178115 /// NM_007150 /// XM_005274730 /// XM_005274731 /// XM_005274732 /// XM_005274733 /// XM_005274734 /// XM_005274735 /// XM_005274736 /// XM_005274737 /// XM_005274738 /// XM_005274739 /// XM_005274740 /// XM_005274741 /// XM_005274742 /// XM_005274744 /// XM_005274745 /// XM_005274746 /// XM_006724843 /// XM_006724844 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203586_s_at NM_001661 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001661.1 /DEF=Homo sapiens ADP-ribosylation factor 4-like (ARF4L), mRNA. /FEA=mRNA /GEN=ARF4L /PROD=ADP-ribosylation factor 4-like /DB_XREF=gi:4502206 /UG=Hs.183153 ADP-ribosylation factor 4-like /FL=gb:BC000043.1 gb:NM_001661.1 gb:L38490.1 gb:U25771.1" NM_001661 ADP-ribosylation factor-like 4D ARL4D 379 NM_001661 0006184 // GTP catabolic process // traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203587_at U25771 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U25771.1 /DEF=Human ADP-ribosylation factor mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor /DB_XREF=gi:808069 /UG=Hs.183153 ADP-ribosylation factor 4-like /FL=gb:BC000043.1 gb:NM_001661.1 gb:L38490.1 gb:U25771.1" U25771 ADP-ribosylation factor-like 4D ARL4D 379 NM_001661 0006184 // GTP catabolic process // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 203588_s_at BG034328 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG034328 /FEA=EST /DB_XREF=gi:12427528 /DB_XREF=est:602302213F1 /CLONE=IMAGE:4403787 /UG=Hs.19131 transcription factor Dp-2 (E2F dimerization partner 2) /FL=gb:NM_006286.1 gb:U18422.1 BG034328 transcription factor Dp-2 (E2F dimerization partner 2) TFDP2 7029 NM_001178138 /// NM_001178139 /// NM_001178140 /// NM_001178141 /// NM_001178142 /// NM_006286 /// XM_005247731 /// XM_005247733 /// XM_005247734 /// XM_005247735 /// XM_006713737 "0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 203589_s_at NM_006286 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006286.1 /DEF=Homo sapiens transcription factor Dp-2 (E2F dimerization partner 2) (TFDP2), mRNA. /FEA=mRNA /GEN=TFDP2 /PROD=transcription factor Dp-2 (E2F dimerizationpartner 2) /DB_XREF=gi:5454111 /UG=Hs.19131 transcription factor Dp-2 (E2F dimerization partner 2) /FL=gb:NM_006286.1 gb:U18422.1" NM_006286 transcription factor Dp-2 (E2F dimerization partner 2) TFDP2 7029 NM_001178138 /// NM_001178139 /// NM_001178140 /// NM_001178141 /// NM_001178142 /// NM_006286 /// XM_005247731 /// XM_005247733 /// XM_005247734 /// XM_005247735 /// XM_006713737 "0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 203590_at NM_006141 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006141.1 /DEF=Homo sapiens dynein, cytoplasmic, light intermediate polypeptide 2 (DNCLI2), mRNA. /FEA=mRNA /GEN=DNCLI2 /PROD=dynein, cytoplasmic, light intermediatepolypeptide 2 /DB_XREF=gi:5453633 /UG=Hs.194625 dynein, cytoplasmic, light intermediate polypeptide 2 /FL=gb:AF035812.1 gb:NM_006141.1" NM_006141 "dynein, cytoplasmic 1, light intermediate chain 2" DYNC1LI2 1783 NM_001286157 /// NM_006141 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0051642 // centrosome localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 203591_s_at NM_000760 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000760.1 /DEF=Homo sapiens colony stimulating factor 3 receptor (granulocyte) (CSF3R), mRNA. /FEA=mRNA /GEN=CSF3R /PROD=colony stimulating factor 3 receptor(granulocyte) /DB_XREF=gi:4503080 /UG=Hs.2175 colony stimulating factor 3 receptor (granulocyte) /FL=gb:M59818.1 gb:NM_000760.1" NM_000760 colony stimulating factor 3 receptor (granulocyte) CSF3R 1441 NM_000760 /// NM_156038 /// NM_156039 /// NM_172313 /// XM_005270492 /// XM_005270493 /// XM_005270495 0006952 // defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203592_s_at NM_005860 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005860.1 /DEF=Homo sapiens follistatin-like 3 (secreted glycoprotein) (FSTL3), mRNA. /FEA=mRNA /GEN=FSTL3 /PROD=follistatin-like 3 glycoprotein /DB_XREF=gi:5031700 /UG=Hs.25348 follistatin-like 3 (secreted glycoprotein) /FL=gb:U76702.1 gb:NM_005860.1" NM_005860 follistatin-like 3 (secreted glycoprotein) FSTL3 10272 NM_005860 "0001503 // ossification // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0045671 // negative regulation of osteoclast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0071248 // cellular response to metal ion // inferred from electronic annotation /// 0090101 // negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0044306 // neuron projection terminus // inferred from electronic annotation 0001968 // fibronectin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0048185 // activin binding // inferred from physical interaction 203593_at NM_012120 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012120.1 /DEF=Homo sapiens CD2-associated protein (CD2AP), mRNA. /FEA=mRNA /GEN=CD2AP /PROD=CD2-associated protein /DB_XREF=gi:11321633 /UG=Hs.265561 CD2-associated protein /FL=gb:NM_012120.1 gb:AF146277.1 gb:AF164377.1" NM_012120 CD2-associated protein CD2AP 23607 NM_012120 /// XM_005248976 /// XM_005248977 "0006461 // protein complex assembly // traceable author statement /// 0006930 // substrate-dependent cell migration, cell extension // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0016050 // vesicle organization // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0048259 // regulation of receptor-mediated endocytosis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0031941 // filamentous actin // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005172 // vascular endothelial growth factor receptor binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 203594_at NM_003729 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003729.1 /DEF=Homo sapiens RNA 3-terminal phosphate cyclase (RPC), mRNA. /FEA=mRNA /GEN=RPC /PROD=RNA 3-terminal phosphate cyclase /DB_XREF=gi:4506588 /UG=Hs.27076 RNA 3-terminal phosphate cyclase /FL=gb:NM_003729.1" NM_003729 RNA 3'-terminal phosphate cyclase RTCA 8634 NM_001130841 /// NM_003729 /// XM_005271298 /// XM_005271299 0006396 // RNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003963 // RNA-3'-phosphate cyclase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203595_s_at N47725 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N47725 /FEA=EST /DB_XREF=gi:1188891 /DB_XREF=est:yy92h11.s1 /CLONE=IMAGE:281061 /UG=Hs.27610 retinoic acid- and interferon-inducible protein (58kD) /FL=gb:U34605.1 gb:NM_012420.1 N47725 interferon-induced protein with tetratricopeptide repeats 5 IFIT5 24138 NM_012420 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203596_s_at NM_012420 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012420.1 /DEF=Homo sapiens retinoic acid- and interferon-inducible protein (58kD) (RI58), mRNA. /FEA=mRNA /GEN=RI58 /PROD=retinoic acid- and interferon-inducible protein(58kD) /DB_XREF=gi:6912629 /UG=Hs.27610 retinoic acid- and interferon-inducible protein (58kD) /FL=gb:U34605.1 gb:NM_012420.1" NM_012420 interferon-induced protein with tetratricopeptide repeats 5 IFIT5 24138 NM_012420 0002376 // immune system process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay 0000049 // tRNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203597_s_at AI734228 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI734228 /FEA=EST /DB_XREF=gi:5055341 /DB_XREF=est:zb57d10.y5 /CLONE=IMAGE:307699 /UG=Hs.28307 WW domain binding protein 4 (formin binding protein 21) /FL=gb:AF071185.1 gb:NM_007187.2 AI734228 WW domain binding protein 4 WBP4 11193 NM_007187 /// XM_005266245 "0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 203598_s_at AK000979 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK000979.1 /DEF=Homo sapiens cDNA FLJ10117 fis, clone HEMBA1002810, highly similar to Homo sapiens formin binding protein 21 mRNA. /FEA=mRNA /DB_XREF=gi:7021977 /UG=Hs.28307 WW domain binding protein 4 (formin binding protein 21) /FL=gb:AF071185.1 gb:NM_007187.2" AK000979 WW domain binding protein 4 WBP4 11193 NM_007187 /// XM_005266245 "0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 203599_s_at NM_007187 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007187.2 /DEF=Homo sapiens WW domain binding protein 4 (formin binding protein 21) (WBP4), mRNA. /FEA=mRNA /GEN=WBP4 /PROD=WW domain-containing binding protein 4 /DB_XREF=gi:9943844 /UG=Hs.28307 WW domain binding protein 4 (formin binding protein 21) /FL=gb:AF071185.1 gb:NM_007187.2" NM_007187 WW domain binding protein 4 WBP4 11193 NM_007187 /// XM_005266245 "0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045292 // mRNA cis splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070064 // proline-rich region binding // inferred from physical interaction 203600_s_at NM_003704 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003704.1 /DEF=Homo sapiens gene with multiple splice variants near HD locus on 4p16.3 (RES4-22), mRNA. /FEA=mRNA /GEN=RES4-22 /PROD=gene with multiple splice variants near HD locuson 4p16.3 /DB_XREF=gi:4506480 /UG=Hs.325987 gene with multiple splice variants near HD locus on 4p16.3 /FL=gb:AB000459.1 gb:NM_003704.1" NM_003704 "family with sequence similarity 193, member A" FAM193A 8603 NM_001256666 /// NM_001256667 /// NM_001256668 /// NM_003704 /// NR_046335 /// NR_046336 /// XM_006713930 /// XM_006713931 /// XM_006713932 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203601_s_at AW574837 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW574837 /FEA=EST /DB_XREF=gi:7246376 /DB_XREF=est:UI-HF-BK0-abj-e-01-0-UI.s1 /CLONE=IMAGE:3056353 /UG=Hs.33532 zinc finger protein 151 (pHZ-67) /FL=gb:NM_003443.1 AW574837 zinc finger and BTB domain containing 17 ZBTB17 7709 NM_001242884 /// NM_001287603 /// NM_001287604 /// NM_003443 /// XM_005245986 /// XM_005245987 "0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203602_s_at NM_003443 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003443.1 /DEF=Homo sapiens zinc finger protein 151 (pHZ-67) (ZNF151), mRNA. /FEA=mRNA /GEN=ZNF151 /PROD=zinc finger protein 151 (pHZ-67) /DB_XREF=gi:4507996 /UG=Hs.33532 zinc finger protein 151 (pHZ-67) /FL=gb:NM_003443.1" NM_003443 zinc finger and BTB domain containing 17 ZBTB17 7709 NM_001242884 /// NM_001287603 /// NM_001287604 /// NM_003443 /// XM_005245986 /// XM_005245987 "0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007398 // ectoderm development // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203603_s_at NM_014795 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014795.1 /DEF=Homo sapiens zinc finger homeobox 1B (ZFHX1B), mRNA. /FEA=mRNA /GEN=ZFHX1B /PROD=zinc finger homeobox 1B /DB_XREF=gi:7662183 /UG=Hs.34871 zinc finger homeobox 1B /FL=gb:AB011141.1 gb:NM_014795.1" NM_014795 zinc finger E-box binding homeobox 2 ZEB2 9839 NM_001171653 /// NM_014795 /// NR_033258 /// XM_006712881 /// XM_006712882 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045636 // positive regulation of melanocyte differentiation // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048023 // positive regulation of melanin biosynthetic process // inferred by curator /// 0048066 // developmental pigmentation // inferred from sequence or structural similarity /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0097324 // melanocyte migration // inferred from sequence or structural similarity /// 1903056 // regulation of melanosome organization // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0019208 // phosphatase regulator activity // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046332 // SMAD binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // inferred from electronic annotation 203604_at N38750 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N38750 /FEA=EST /DB_XREF=gi:1161957 /DB_XREF=est:yy42c06.s1 /CLONE=IMAGE:273898 /UG=Hs.48450 KIAA0222 gene product /FL=gb:D86975.1 gb:NM_014643.1 N38750 zinc finger protein 516 ZNF516 9658 NM_014643 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203605_at NM_003136 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003136.1 /DEF=Homo sapiens signal recognition particle 54kD (SRP54), mRNA. /FEA=mRNA /GEN=SRP54 /PROD=signal recognition particle 54kD /DB_XREF=gi:4507214 /UG=Hs.49346 signal recognition particle 54kD /FL=gb:U51920.1 gb:BC000652.1 gb:BC003389.1 gb:NM_003136.1" NM_003136 signal recognition particle 54kDa SRP54 6729 NM_001146282 /// NM_003136 /// XM_005268024 "0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred by curator /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0006616 // SRP-dependent cotranslational protein targeting to membrane, translocation // inferred from sequence or structural similarity /// 0006617 // SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0042493 // response to drug // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045047 // protein targeting to ER // inferred from mutant phenotype" "0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation" 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005525 // GTP binding // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0008312 // 7S RNA binding // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019003 // GDP binding // inferred from direct assay /// 0030942 // endoplasmic reticulum signal peptide binding // inferred from direct assay /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay 203606_at NM_004553 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004553.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 6 (13kD) (NADH-coenzyme Q reductase) (NDUFS6), mRNA. /FEA=mRNA /GEN=NDUFS6 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 6(13kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758791 /UG=Hs.49767 NADH dehydrogenase (ubiquinone) Fe-S protein 6 (13kD) (NADH-coenzyme Q reductase) /FL=gb:AF044959.1 gb:NM_004553.1" NM_004553 "NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)" NDUFS6 4726 NM_004553 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006936 // muscle contraction // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0061458 // reproductive system development // inferred from electronic annotation /// 0070584 // mitochondrion morphogenesis // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation" 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0009055 // electron carrier activity // non-traceable author statement 203607_at NM_014937 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014937.1 /DEF=Homo sapiens KIAA0966 protein (KIAA0966), mRNA. /FEA=mRNA /GEN=KIAA0966 /PROD=KIAA0966 protein /DB_XREF=gi:7662413 /UG=Hs.52463 KIAA0966 protein /FL=gb:AF113227.1 gb:AB023183.1 gb:NM_014937.1" NM_014937 inositol polyphosphate-5-phosphatase F INPP5F 22876 NM_001243194 /// NM_001243195 /// NM_014937 /// XM_006717719 /// XM_006717720 0008152 // metabolic process // inferred from electronic annotation /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0031161 // phosphatidylinositol catabolic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation 0016787 // hydrolase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation 203608_at AL031230 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL031230 /DEF=Human DNA sequence from clone 73M23 on chromosome 6p22.2-22.3. Contains the 5 part of the possibly alternatively spliced gene for Phosphatidylinositol-glycan-specific Phospholipase D 1 precursor (EC 3.1.4.50, PIGPLD1, Glycoprotein Phospholipase D... /FEA=mRNA_5 /DB_XREF=gi:3947845 /UG=Hs.5299 aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) /FL=gb:NM_001080.1" AL031230 "aldehyde dehydrogenase 5 family, member A1" ALDH5A1 7915 NM_001080 /// NM_170740 0006006 // glucose metabolic process // inferred from sequence or structural similarity /// 0006083 // acetate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006536 // glutamate metabolic process // inferred from sequence or structural similarity /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006650 // glycerophospholipid metabolic process // inferred from sequence or structural similarity /// 0006678 // glucosylceramide metabolic process // inferred from electronic annotation /// 0006681 // galactosylceramide metabolic process // inferred from sequence or structural similarity /// 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from direct assay /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from mutant phenotype /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from sequence or structural similarity /// 0042135 // neurotransmitter catabolic process // inferred from sequence or structural similarity /// 0046459 // short-chain fatty acid metabolic process // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement "0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from direct assay /// 0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from sequence or structural similarity /// 0009013 // succinate-semialdehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred by curator" 203609_s_at NM_001080 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001080.1 /DEF=Homo sapiens aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) (ALDH5A1), mRNA. /FEA=mRNA /GEN=ALDH5A1 /PROD=aldehyde dehydrogenase 5 family, member A1(succinate-semialdehyde dehydrogenase) /DB_XREF=gi:4507228 /UG=Hs.5299 aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) /FL=gb:NM_001080.1" NM_001080 "aldehyde dehydrogenase 5 family, member A1" ALDH5A1 7915 NM_001080 /// NM_170740 0006006 // glucose metabolic process // inferred from sequence or structural similarity /// 0006083 // acetate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006536 // glutamate metabolic process // inferred from sequence or structural similarity /// 0006541 // glutamine metabolic process // inferred from sequence or structural similarity /// 0006650 // glycerophospholipid metabolic process // inferred from sequence or structural similarity /// 0006678 // glucosylceramide metabolic process // inferred from electronic annotation /// 0006681 // galactosylceramide metabolic process // inferred from sequence or structural similarity /// 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007417 // central nervous system development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009448 // gamma-aminobutyric acid metabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from direct assay /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from electronic annotation /// 0009450 // gamma-aminobutyric acid catabolic process // inferred from mutant phenotype /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from sequence or structural similarity /// 0042135 // neurotransmitter catabolic process // inferred from sequence or structural similarity /// 0046459 // short-chain fatty acid metabolic process // inferred from sequence or structural similarity /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement "0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from direct assay /// 0004777 // succinate-semialdehyde dehydrogenase (NAD+) activity // inferred from sequence or structural similarity /// 0009013 // succinate-semialdehyde dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred by curator" 203610_s_at AI363270 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI363270 /FEA=EST /DB_XREF=gi:4114891 /DB_XREF=est:qy56f11.x1 /CLONE=IMAGE:2016045 /UG=Hs.59545 ring finger protein 15 /FL=gb:U90547.1 gb:NM_006355.1 AI363270 tripartite motif containing 38 TRIM38 10475 NM_006355 /// XM_005248799 /// XM_005248800 /// XR_241880 0007165 // signal transduction // inferred from mutant phenotype /// 0032648 // regulation of interferon-beta production // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from electronic annotation /// 0046598 // positive regulation of viral entry into host cell // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203611_at NM_005652 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005652.1 /DEF=Homo sapiens telomeric repeat binding factor 2 (TERF2), mRNA. /FEA=mRNA /GEN=TERF2 /PROD=telomeric repeat binding factor 2 /DB_XREF=gi:5032168 /UG=Hs.100030 telomeric repeat binding factor 2 /FL=gb:AF002999.1 gb:NM_005652.1" NM_005652 telomeric repeat binding factor 2 TERF2 7014 NM_005652 /// XM_005256121 /// XM_005256122 /// XM_005256123 /// XM_005256124 "0000723 // telomere maintenance // inferred from mutant phenotype /// 0000723 // telomere maintenance // traceable author statement /// 0001309 // age-dependent telomere shortening // non-traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007004 // telomere maintenance via telomerase // inferred by curator /// 0007049 // cell cycle // inferred from electronic annotation /// 0010834 // telomere maintenance via telomere shortening // inferred from mutant phenotype /// 0016233 // telomere capping // inferred from mutant phenotype /// 0031627 // telomeric loop formation // inferred from direct assay /// 0031848 // protection from non-homologous end joining at telomere // inferred from mutant phenotype /// 0032205 // negative regulation of telomere maintenance // inferred from direct assay /// 0032206 // positive regulation of telomere maintenance // inferred from electronic annotation /// 0032214 // negative regulation of telomere maintenance via semi-conservative replication // non-traceable author statement /// 0070198 // protein localization to chromosome, telomeric region // inferred from mutant phenotype /// 0090398 // cellular senescence // non-traceable author statement" "0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0030870 // Mre11 complex // inferred from direct assay" 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction 203612_at NM_004053 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004053.1 /DEF=Homo sapiens bystin-like (BYSL), mRNA. /FEA=mRNA /GEN=BYSL /PROD=bystin /DB_XREF=gi:4757881 /UG=Hs.106880 bystin-like /FL=gb:L36720.1 gb:NM_004053.1" NM_004053 bystin-like BYSL 705 NM_004053 "0000462 // maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203613_s_at NM_002493 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002493.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 (17kD, B17) (NDUFB6), mRNA. /FEA=mRNA /GEN=NDUFB6 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 6 (17kD, B17) /DB_XREF=gi:4505364 /UG=Hs.109646 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 (17kD, B17) /FL=gb:AF035840.1 gb:NM_002493.1 gb:AF067167.1" NM_002493 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa" NDUFB6 4712 NM_001199987 /// NM_002493 /// NM_182739 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203614_at NM_021645 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021645.1 /DEF=Homo sapiens KIAA0266 gene product (KIAA0266), mRNA. /FEA=mRNA /GEN=KIAA0266 /PROD=KIAA0266 gene product /DB_XREF=gi:11063982 /UG=Hs.127376 KIAA0266 gene product /FL=gb:NM_021645.1 gb:D87455.1" NM_021645 "ALG11, alpha-1,2-mannosyltransferase /// UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)" ALG11 /// UTP14C 9724 /// 440138 NM_001004127 /// NM_021645 /// NR_036571 0006364 // rRNA processing // inferred from electronic annotation /// 0006488 // dolichol-linked oligosaccharide biosynthetic process // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0097502 // mannosylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019013 // viral nucleocapsid // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0032040 // small-subunit processome // inferred from electronic annotation "0004377 // GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation" 203615_x_at NM_001055 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001055.1 /DEF=Homo sapiens sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (SULT1A1), mRNA. /FEA=mRNA /GEN=SULT1A1 /PROD=sulfotransferase family, cytosolic, 1A,phenol-preferring, member 1 /DB_XREF=gi:4507300 /UG=Hs.142 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 /FL=gb:BC000923.2 gb:L10819.1 gb:L19955.1 gb:L19999.1 gb:NM_001055.1 gb:U09031.1 gb:U26309.1" NM_001055 "sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1" SULT1A1 6817 NM_001055 /// NM_177529 /// NM_177530 /// NM_177534 /// NM_177536 /// XM_005255522 /// XM_006721078 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0009308 // amine metabolic process // traceable author statement /// 0009812 // flavonoid metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0051923 // sulfation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004062 // aryl sulfotransferase activity // inferred from direct assay /// 0004062 // aryl sulfotransferase activity // traceable author statement /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0047894 // flavonol 3-sulfotransferase activity // inferred from direct assay /// 0050294 // steroid sulfotransferase activity // inferred from direct assay 203616_at NM_002690 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002690.1 /DEF=Homo sapiens polymerase (DNA directed), beta (POLB), mRNA. /FEA=mRNA /GEN=POLB /PROD=polymerase (DNA directed), beta /DB_XREF=gi:4505930 /UG=Hs.180107 polymerase (DNA directed), beta /FL=gb:M13140.1 gb:L11607.1 gb:NM_002690.1 gb:D29013.1" NM_002690 "polymerase (DNA directed), beta" POLB 5423 NM_002690 /// XM_005273535 /// XM_005273536 /// XM_005273537 /// XM_005273538 /// XM_005273539 /// XM_005273540 /// XM_006716353 /// XR_428311 "0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // inferred from mutant phenotype /// 0006284 // base-excision repair // traceable author statement /// 0006287 // base-excision repair, gap-filling // inferred from electronic annotation /// 0006290 // pyrimidine dimer repair // inferred from electronic annotation /// 0006297 // nucleotide-excision repair, DNA gap filling // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0051402 // neuron apoptotic process // inferred from electronic annotation /// 0071897 // DNA biosynthetic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005876 // spindle microtubule // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203617_x_at NM_005229 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005229.2 /DEF=Homo sapiens ELK1, member of ETS oncogene family (ELK1), mRNA. /FEA=mRNA /GEN=ELK1 /PROD=ELK1 protein /DB_XREF=gi:11496880 /UG=Hs.181128 ELK1, member of ETS oncogene family /FL=gb:NM_005229.2 gb:AB016193.1" NM_005229 "ELK1, member of ETS oncogene family" ELK1 2002 NM_001114123 /// NM_001257168 /// NM_005229 "0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement" 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203618_at AB023167 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB023167.1 /DEF=Homo sapiens mRNA for KIAA0950 protein, partial cds. /FEA=mRNA /GEN=KIAA0950 /PROD=KIAA0950 protein /DB_XREF=gi:4589543 /UG=Hs.182859 lifeguard /FL=gb:BC000051.1 gb:AF190461.1 gb:NM_012306.1" AB023167 Fas apoptotic inhibitory molecule 2 FAIM2 23017 NM_012306 /// XM_005268730 0006915 // apoptotic process // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0021680 // cerebellar Purkinje cell layer development // inferred from sequence or structural similarity /// 0021681 // cerebellar granular layer development // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 203619_s_at NM_012306 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012306.1 /DEF=Homo sapiens lifeguard (KIAA0950), mRNA. /FEA=mRNA /GEN=KIAA0950 /PROD=lifeguard /DB_XREF=gi:6912467 /UG=Hs.182859 lifeguard /FL=gb:BC000051.1 gb:AF190461.1 gb:NM_012306.1" NM_012306 Fas apoptotic inhibitory molecule 2 FAIM2 23017 NM_012306 /// XM_005268730 0006915 // apoptotic process // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from sequence or structural similarity /// 0021680 // cerebellar Purkinje cell layer development // inferred from sequence or structural similarity /// 0021681 // cerebellar granular layer development // inferred from sequence or structural similarity /// 0021702 // cerebellar Purkinje cell differentiation // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from mutant phenotype 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 203620_s_at NM_014824 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014824.1 /DEF=Homo sapiens KIAA0769 gene product (KIAA0769), mRNA. /FEA=mRNA /GEN=KIAA0769 /PROD=KIAA0769 gene product /DB_XREF=gi:7662295 /UG=Hs.19056 KIAA0769 gene product /FL=gb:AB018312.1 gb:NM_014824.1" NM_014824 FCH and double SH3 domains 2 FCHSD2 9873 NM_014824 0005515 // protein binding // inferred from physical interaction 203621_at NM_002492 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002492.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 (16kD, SGDH) (NDUFB5), mRNA. /FEA=mRNA /GEN=NDUFB5 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 5 (16kD, SGDH) /DB_XREF=gi:4505362 /UG=Hs.19236 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 (16kD, SGDH) /FL=gb:BC005271.1 gb:AF047181.1 gb:NM_002492.1" NM_002492 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa" NDUFB5 4711 NM_001199957 /// NM_001199958 /// NM_002492 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070469 // respiratory chain // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 203622_s_at NM_020143 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020143.1 /DEF=Homo sapiens putatative 28 kDa protein (LOC56902), mRNA. /FEA=mRNA /GEN=LOC56902 /PROD=putatative 28 kDa protein /DB_XREF=gi:10047139 /UG=Hs.193384 putatative 28 kDa protein /FL=gb:NM_020143.1 gb:AF164799.1" NM_020143 partner of NOB1 homolog (S. cerevisiae) PNO1 56902 NM_020143 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203623_at AI675453 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI675453 /FEA=EST /DB_XREF=gi:4875933 /DB_XREF=est:wb99f04.x1 /CLONE=IMAGE:2313823 /UG=Hs.21432 SEX gene /FL=gb:NM_017514.1 AI675453 plexin A3 PLXNA3 55558 NM_017514 /// XM_005274705 /// XM_005274706 /// XM_006724829 /// XM_006724830 /// XR_430556 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021860 // pyramidal neuron development // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0051495 // positive regulation of cytoskeleton organization // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // non-traceable author statement 0002116 // semaphorin receptor complex // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017154 // semaphorin receptor activity // inferred from electronic annotation 203624_at NM_005088 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005088.1 /DEF=Homo sapiens DNA segment on chromosome X and Y (unique) 155 expressed sequence (DXYS155E), mRNA. /FEA=mRNA /GEN=DXYS155E /PROD=DNA segment on chromosome X and Y (unique) 155expressed sequence /DB_XREF=gi:10835221 /UG=Hs.21595 DNA segment on chromosome X and Y (unique) 155 expressed sequence /FL=gb:NM_005088.1" NM_005088 A kinase (PRKA) anchor protein 17A AKAP17A 8227 NM_005088 /// NR_027383 "0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030187 // melatonin biosynthetic process // inferred from direct assay /// 0030187 // melatonin biosynthetic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042113 // B cell activation // non-traceable author statement /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0046219 // indolalkylamine biosynthetic process // traceable author statement /// 2000019 // negative regulation of male gonad development // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016607 // nuclear speck // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // inferred from electronic annotation /// 0008171 // O-methyltransferase activity // traceable author statement /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from direct assay /// 0017096 // acetylserotonin O-methyltransferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051018 // protein kinase A binding // inferred from direct assay 203625_x_at BG105365 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG105365 /FEA=EST /DB_XREF=gi:12599141 /DB_XREF=est:602312473F1 /CLONE=IMAGE:4422043 /UG=Hs.23348 S-phase kinase-associated protein 2 (p45) /FL=gb:NM_005983.1 gb:U33761.1 BG105365 "S-phase kinase-associated protein 2, E3 ubiquitin protein ligase" SKP2 6502 NM_001243120 /// NM_005983 /// NM_032637 /// XM_006714487 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071460 // cellular response to cell-matrix adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016235 // aggresome // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203626_s_at NM_005983 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005983.1 /DEF=Homo sapiens S-phase kinase-associated protein 2 (p45) (SKP2), mRNA. /FEA=mRNA /GEN=SKP2 /PROD=S-phase kinase-associated protein 2 (p45) /DB_XREF=gi:5174684 /UG=Hs.23348 S-phase kinase-associated protein 2 (p45) /FL=gb:NM_005983.1 gb:U33761.1" NM_005983 "S-phase kinase-associated protein 2, E3 ubiquitin protein ligase" SKP2 6502 NM_001243120 /// NM_005983 /// NM_032637 /// XM_006714487 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0033148 // positive regulation of intracellular estrogen receptor signaling pathway // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071460 // cellular response to cell-matrix adhesion // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016235 // aggresome // inferred from direct assay /// 0019005 // SCF ubiquitin ligase complex // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203627_at AI830698 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI830698 /FEA=EST /DB_XREF=gi:5451454 /DB_XREF=est:wj52f06.x1 /CLONE=IMAGE:2406467 /UG=Hs.239176 insulin-like growth factor 1 receptor /FL=gb:NM_000875.2 AI830698 insulin-like growth factor 1 receptor IGF1R 3480 NM_000875 /// NM_001291858 /// NM_152452 /// XM_005254896 /// XM_005254897 /// XM_006720486 /// XM_006720487 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred by curator /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051389 // inactivation of MAPKK activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction" 203628_at H05812 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:H05812 /FEA=EST /DB_XREF=gi:869364 /DB_XREF=est:yl77f04.s1 /CLONE=IMAGE:44149 /UG=Hs.239176 insulin-like growth factor 1 receptor /FL=gb:NM_000875.2 H05812 insulin-like growth factor 1 receptor IGF1R 3480 NM_000875 /// NM_001291858 /// NM_152452 /// XM_005254896 /// XM_005254897 /// XM_006720486 /// XM_006720487 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006955 // immune response // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred by curator /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030238 // male sex determination // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031017 // exocrine pancreas development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay /// 0051054 // positive regulation of DNA metabolic process // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051389 // inactivation of MAPKK activity // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0090031 // positive regulation of steroid hormone biosynthetic process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor-activated receptor activity // inferred from direct assay /// 0005158 // insulin receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043559 // insulin binding // inferred from physical interaction /// 0043560 // insulin receptor substrate binding // inferred from physical interaction" 203629_s_at AU152134 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU152134 /FEA=EST /DB_XREF=gi:11013655 /DB_XREF=est:AU152134 /CLONE=NT2RP3000274 /UG=Hs.239631 golgi transport complex 1 (90 kDa subunit) /FL=gb:AF058718.1 gb:NM_006348.1 AU152134 component of oligomeric golgi complex 5 COG5 10466 NM_001161520 /// NM_006348 /// NM_181733 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0017119 // Golgi transport complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 203630_s_at NM_006348 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006348.1 /DEF=Homo sapiens golgi transport complex 1 (90 kDa subunit) (GOLTC1), mRNA. /FEA=mRNA /GEN=GOLTC1 /PROD=golgi transport complex 1 (90 kDa subunit) /DB_XREF=gi:5453669 /UG=Hs.239631 golgi transport complex 1 (90 kDa subunit) /FL=gb:AF058718.1 gb:NM_006348.1" NM_006348 component of oligomeric golgi complex 5 COG5 10466 NM_001161520 /// NM_006348 /// NM_181733 0006810 // transport // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017119 // Golgi transport complex // inferred from direct assay /// 0017119 // Golgi transport complex // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 203631_s_at AF202640 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF202640.1 /DEF=Homo sapiens orphan G-protein coupled receptor (GPRC5B) mRNA, complete cds. /FEA=mRNA /GEN=GPRC5B /PROD=orphan G-protein coupled receptor /DB_XREF=gi:7682556 /UG=Hs.242407 G protein-coupled receptor, family C, group 5, member B /FL=gb:AF181862.1 gb:AF202640.1 gb:NM_016235.1" AF202640 "G protein-coupled receptor, class C, group 5, member B" GPRC5B 51704 NM_016235 /// XM_005255357 /// XM_006721051 /// XM_006721052 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0060907 // positive regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005118 // sevenless binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0030295 // protein kinase activator activity // inferred from direct assay 203632_s_at NM_016235 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016235.1 /DEF=Homo sapiens G protein-coupled receptor, family C, group 5, member B (GPRC5B), mRNA. /FEA=mRNA /GEN=GPRC5B /PROD=G protein-coupled receptor, family C, group 5,member B, precursor /DB_XREF=gi:7706450 /UG=Hs.242407 G protein-coupled receptor, family C, group 5, member B /FL=gb:AF181862.1 gb:AF202640.1 gb:NM_016235.1" NM_016235 "G protein-coupled receptor, class C, group 5, member B" GPRC5B 51704 NM_016235 /// XM_005255357 /// XM_006721051 /// XM_006721052 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0060907 // positive regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001664 // G-protein coupled receptor binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005118 // sevenless binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0030295 // protein kinase activator activity // inferred from direct assay 203633_at BF001714 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF001714 /FEA=EST /DB_XREF=gi:10701989 /DB_XREF=est:7g92b09.x1 /CLONE=IMAGE:3313913 /UG=Hs.259785 carnitine palmitoyltransferase I, liver /FL=gb:NM_001876.1 gb:L39211.1" BF001714 carnitine palmitoyltransferase 1A (liver) CPT1A 1374 NM_001031847 /// NM_001876 /// XM_005273762 /// XM_005273763 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046320 // regulation of fatty acid oxidation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004095 // carnitine O-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation" 203634_s_at NM_001876 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001876.1 /DEF=Homo sapiens carnitine palmitoyltransferase I, liver (CPT1A), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CPT1A /PROD=liver carnitine palmitoyltransferase I /DB_XREF=gi:4503020 /UG=Hs.259785 carnitine palmitoyltransferase I, liver /FL=gb:NM_001876.1 gb:L39211.1" NM_001876 carnitine palmitoyltransferase 1A (liver) CPT1A 1374 NM_001031847 /// NM_001876 /// XM_005273762 /// XM_005273763 0001676 // long-chain fatty acid metabolic process // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046320 // regulation of fatty acid oxidation // inferred from electronic annotation /// 0050796 // regulation of insulin secretion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0004095 // carnitine O-palmitoyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation" 203635_at NM_006052 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006052.1 /DEF=Homo sapiens Down syndrome critical region gene 3 (DSCR3), mRNA. /FEA=mRNA /GEN=DSCR3 /PROD=Down syndrome critical region protein 3 /DB_XREF=gi:5174424 /UG=Hs.26146 Down syndrome critical region gene 3 /FL=gb:D87343.1 gb:NM_006052.1" NM_006052 Down syndrome critical region gene 3 DSCR3 10311 NM_006052 /// XM_005260909 /// XM_005260911 0007034 // vacuolar transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0030904 // retromer complex // inferred from electronic annotation 203636_at BE967532 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE967532 /FEA=EST /DB_XREF=gi:10578237 /DB_XREF=est:601649050F1 /CLONE=IMAGE:3932868 /UG=Hs.27695 midline 1 (OpitzBBB syndrome) /FL=gb:AF269101.1 gb:AF230976.1 gb:AF035360.1 gb:NM_000381.1 BE967532 midline 1 MID1 4281 NM_000381 /// NM_001098624 /// NM_001193277 /// NM_001193278 /// NM_001193279 /// NM_001193280 /// NM_001193281 /// NM_033289 /// NM_033290 /// NM_033291 /// XM_005274536 /// XM_005274537 /// XM_005274538 /// XM_006724492 /// XM_006724493 /// XR_247298 /// XR_247299 /// XR_247300 /// XR_250630 /// XR_250631 /// XR_250632 /// XR_254127 /// XR_254128 /// XR_254129 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0007389 // pattern specification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 203637_s_at NM_000381 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000381.1 /DEF=Homo sapiens midline 1 (OpitzBBB syndrome) (MID1), mRNA. /FEA=mRNA /GEN=MID1 /PROD=midline 1 /DB_XREF=gi:4557752 /UG=Hs.27695 midline 1 (OpitzBBB syndrome) /FL=gb:AF269101.1 gb:AF230976.1 gb:AF035360.1 gb:NM_000381.1" NM_000381 midline 1 MID1 4281 NM_000381 /// NM_001098624 /// NM_001193277 /// NM_001193278 /// NM_001193279 /// NM_001193280 /// NM_001193281 /// NM_033289 /// NM_033290 /// NM_033291 /// XM_005274536 /// XM_005274537 /// XM_005274538 /// XM_006724492 /// XM_006724493 /// XR_247298 /// XR_247299 /// XR_247300 /// XR_250630 /// XR_250631 /// XR_250632 /// XR_254127 /// XR_254128 /// XR_254129 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0007389 // pattern specification process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from mutant phenotype /// 0035372 // protein localization to microtubule // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005875 // microtubule associated complex // traceable author statement /// 0005881 // cytoplasmic microtubule // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from mutant phenotype /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from physical interaction 203638_s_at NM_022969 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022969.1 /DEF=Homo sapiens fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) (FGFR2), transcript variant 2, mRNA. /FEA=mRNA /GEN=FGFR2 /PROD=fibroblast growth factor receptor 2, isoform 2precursor /DB_XREF=gi:13186252 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022969.1 gb:M97193.1 gb:M80634.1" NM_022969 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction" 203639_s_at M80634 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M80634.1 /DEF=Human keratinocyte growth factor receptor mRNA, complete cds. /FEA=mRNA /PROD=keratinocyte growth factor receptor /DB_XREF=gi:186740 /UG=Hs.278581 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) /FL=gb:NM_022969.1 gb:M97193.1 gb:M80634.1" M80634 fibroblast growth factor receptor 2 FGFR2 2263 NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction" 203640_at BE328496 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE328496 /FEA=EST /DB_XREF=gi:9202272 /DB_XREF=est:hs98f09.x1 /CLONE=IMAGE:3145289 /UG=Hs.283609 hypothetical protein PRO2032 /FL=gb:AF116683.1 gb:NM_018615.1 BE328496 muscleblind-like splicing regulator 2 MBNL2 10150 NM_144778 /// NM_207304 /// XM_005254018 /// XM_005254019 /// XM_005254020 /// XM_005254021 /// XM_005254022 /// XM_006719912 "0000381 // regulation of alternative mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203641_s_at BF002844 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF002844 /FEA=EST /DB_XREF=gi:10703119 /DB_XREF=est:7g49h05.x1 /CLONE=IMAGE:3309849 /UG=Hs.300855 KIAA0977 protein /FL=gb:AB023194.1 gb:NM_014900.1 BF002844 cordon-bleu WH2 repeat protein-like 1 COBLL1 22837 NM_001278458 /// NM_001278460 /// NM_001278461 /// NM_014900 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 203642_s_at NM_014900 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014900.1 /DEF=Homo sapiens KIAA0977 protein (KIAA0977), mRNA. /FEA=mRNA /GEN=KIAA0977 /PROD=KIAA0977 protein /DB_XREF=gi:7662427 /UG=Hs.300855 KIAA0977 protein /FL=gb:AB023194.1 gb:NM_014900.1" NM_014900 cordon-bleu WH2 repeat protein-like 1 COBLL1 22837 NM_001278458 /// NM_001278460 /// NM_001278461 /// NM_014900 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation 203643_at NM_006494 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006494.1 /DEF=Homo sapiens Ets2 repressor factor (ERF), mRNA. /FEA=mRNA /GEN=ERF /PROD=Ets2 repressor factor /DB_XREF=gi:5729813 /UG=Hs.333069 Ets2 repressor factor /FL=gb:U15655.1 gb:NM_006494.1" NM_006494 Ets2 repressor factor ERF 2077 NM_006494 /// XM_005258643 /// XM_005258644 /// XM_006723079 /// XM_006723080 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007049 // cell cycle // non-traceable author statement /// 0010668 // ectodermal cell differentiation // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0060707 // trophoblast giant cell differentiation // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation" 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203644_s_at AI629033 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI629033 /FEA=EST /DB_XREF=gi:4665833 /DB_XREF=est:ty79g04.x1 /CLONE=IMAGE:2285334 /UG=Hs.40109 KIAA0872 protein /FL=gb:AB020679.1 gb:NM_014940.1 AI629033 MON1 secretory trafficking family member B MON1B 22879 NM_001286639 /// NM_001286640 /// NM_014940 0005515 // protein binding // inferred from physical interaction 203645_s_at NM_004244 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004244.1 /DEF=Homo sapiens CD163 antigen (CD163), mRNA. /FEA=mRNA /GEN=CD163 /PROD=CD163 antigen /DB_XREF=gi:4758721 /UG=Hs.74076 CD163 antigen /FL=gb:NM_004244.1" NM_004244 CD163 molecule CD163 9332 NM_004244 /// NM_203416 /// XM_005253528 /// XM_005253529 /// XR_429039 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // non-traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005044 // scavenger receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203646_at NM_004109 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004109.2 /DEF=Homo sapiens ferredoxin 1 (FDX1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FDX1 /PROD=ferredoxin 1 precursor /DB_XREF=gi:13677224 /UG=Hs.744 ferredoxin 1 /FL=gb:NM_004109.2 gb:J03548.1 gb:M18003.1 gb:M34788.1" NM_004109 ferredoxin 1 FDX1 2230 NM_004109 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement "0005506 // iron ion binding // traceable author statement /// 0009055 // electron carrier activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from direct assay" 203647_s_at M18003 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M18003.1 /DEF=Human ferredoxin mRNA, complete cds. /FEA=mRNA /PROD=ferredoxin /DB_XREF=gi:182493 /UG=Hs.744 ferredoxin 1 /FL=gb:NM_004109.2 gb:J03548.1 gb:M18003.1 gb:M34788.1" M18003 ferredoxin 1 FDX1 2230 NM_004109 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement "0005506 // iron ion binding // traceable author statement /// 0009055 // electron carrier activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from direct assay" 203648_at NM_014760 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014760.1 /DEF=Homo sapiens KIAA0218 gene product (KIAA0218), mRNA. /FEA=mRNA /GEN=KIAA0218 /PROD=KIAA0218 gene product /DB_XREF=gi:7662007 /UG=Hs.75863 KIAA0218 gene product /FL=gb:D86972.1 gb:NM_014760.1" NM_014760 TatD DNase domain containing 2 TATDN2 9797 NM_014760 "0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006308 // DNA catabolic process // not recorded /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0043229 // intracellular organelle // not recorded "0004518 // nuclease activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203649_s_at NM_000300 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000300.1 /DEF=Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PLA2G2A /PROD=phospholipase A2, group IIA (platelets, synovialfluid) /DB_XREF=gi:4505848 /UG=Hs.76422 phospholipase A2, group IIA (platelets, synovial fluid) /FL=gb:M22430.1 gb:NM_000300.1" NM_000300 "phospholipase A2, group IIA (platelets, synovial fluid)" PLA2G2A 5320 NM_000300 /// NM_001161727 /// NM_001161728 /// NM_001161729 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0010744 // positive regulation of macrophage derived foam cell differentiation // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // traceable author statement /// 0036148 // phosphatidylglycerol acyl-chain remodeling // traceable author statement /// 0036149 // phosphatidylinositol acyl-chain remodeling // traceable author statement /// 0036150 // phosphatidylserine acyl-chain remodeling // traceable author statement /// 0036151 // phosphatidylcholine acyl-chain remodeling // traceable author statement /// 0036152 // phosphatidylethanolamine acyl-chain remodeling // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046473 // phosphatidic acid metabolic process // inferred from direct assay /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0050830 // defense response to Gram-positive bacterium // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from direct assay /// 0004623 // phospholipase A2 activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047498 // calcium-dependent phospholipase A2 activity // traceable author statement 203650_at NM_006404 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006404.1 /DEF=Homo sapiens protein C receptor, endothelial (EPCR) (PROCR), mRNA. /FEA=mRNA /GEN=PROCR /PROD=protein C receptor, endothelial (EPCR) /DB_XREF=gi:5453645 /UG=Hs.82353 protein C receptor, endothelial (EPCR) /FL=gb:NM_006404.1 gb:L35545.1" NM_006404 "protein C receptor, endothelial" PROCR 10544 NM_006404 /// XM_005260251 /// XM_006723682 0006955 // immune response // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0050819 // negative regulation of coagulation // inferred from mutant phenotype 0005813 // centrosome // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203651_at NM_014733 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014733.1 /DEF=Homo sapiens KIAA0305 gene product (KIAA0305), mRNA. /FEA=mRNA /GEN=KIAA0305 /PROD=KIAA0305 gene product /DB_XREF=gi:7662047 /UG=Hs.83790 KIAA0305 gene product /FL=gb:AB002303.1 gb:NM_014733.1" NM_014733 "zinc finger, FYVE domain containing 16" ZFYVE16 9765 NM_001105251 /// NM_001284236 /// NM_001284237 /// NM_014733 /// XM_005248632 /// XM_005248634 0006622 // protein targeting to lysosome // inferred from mutant phenotype /// 0007165 // signal transduction // non-traceable author statement /// 0016050 // vesicle organization // non-traceable author statement /// 0016197 // endosomal transport // inferred from mutant phenotype /// 0030100 // regulation of endocytosis // traceable author statement /// 0030509 // BMP signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0005515 // protein binding // inferred from physical interaction /// 0005545 // 1-phosphatidylinositol binding // inferred from direct assay /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay /// 0008565 // protein transporter activity // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation" 203652_at NM_002419 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002419.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 11 (MAP3K11), mRNA. /FEA=mRNA /GEN=MAP3K11 /PROD=mitogen-activated protein kinase kinase kinase11 /DB_XREF=gi:4505194 /UG=Hs.89449 mitogen-activated protein kinase kinase kinase 11 /FL=gb:NM_002419.1 gb:U07747.1 gb:L32976.1" NM_002419 mitogen-activated protein kinase kinase kinase 11 MAP3K11 4296 NM_002419 /// XR_428915 0000080 // mitotic G1 phase // inferred from mutant phenotype /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007017 // microtubule-based process // inferred from mutant phenotype /// 0007254 // JNK cascade // traceable author statement /// 0007256 // activation of JNKK activity // inferred from electronic annotation /// 0007257 // activation of JUN kinase activity // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043507 // positive regulation of JUN kinase activity // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0046330 // positive regulation of JNK cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0016020 // membrane // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004706 // JUN kinase kinase kinase activity // inferred from sequence or structural similarity /// 0004709 // MAP kinase kinase kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031434 // mitogen-activated protein kinase kinase binding // inferred from electronic annotation /// 0031435 // mitogen-activated protein kinase kinase kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0048365 // Rac GTPase binding // inferred from electronic annotation" 203653_s_at BG391060 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG391060 /FEA=EST /DB_XREF=gi:13284508 /DB_XREF=est:602417755F1 /CLONE=IMAGE:4537164 /UG=Hs.966 coilin /FL=gb:U06632.1 gb:NM_004645.1 BG391060 coilin COIL 8161 NM_004645 0055114 // oxidation-reduction process // inferred from electronic annotation 0001674 // female germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0015036 // disulfide oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203654_s_at NM_004645 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004645.1 /DEF=Homo sapiens coilin (COIL), mRNA. /FEA=mRNA /GEN=COIL /PROD=coilin /DB_XREF=gi:4758023 /UG=Hs.966 coilin /FL=gb:U06632.1 gb:NM_004645.1" NM_004645 coilin COIL 8161 NM_004645 0055114 // oxidation-reduction process // inferred from electronic annotation 0001674 // female germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0015036 // disulfide oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 203655_at NM_006297 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006297.1 /DEF=Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1), mRNA. /FEA=mRNA /GEN=XRCC1 /PROD=X-ray repair cross complementing protein 1 /DB_XREF=gi:5454171 /UG=Hs.98493 X-ray repair complementing defective repair in Chinese hamster cells 1 /FL=gb:M36089.1 gb:NM_006297.1" NM_006297 X-ray repair complementing defective repair in Chinese hamster cells 1 XRCC1 7515 NM_006297 0000012 // single strand break repair // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // not recorded /// 0006284 // base-excision repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement 0003684 // damaged DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203656_at NM_014845 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014845.1 /DEF=Homo sapiens KIAA0274 gene product (KIAA0274), mRNA. /FEA=mRNA /GEN=KIAA0274 /PROD=KIAA0274 gene product /DB_XREF=gi:7662033 /UG=Hs.10037 KIAA0274 gene product /FL=gb:D87464.1 gb:NM_014845.1" NM_014845 "FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)" FIG4 9896 NM_014845 /// XM_006715622 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007033 // vacuole organization // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0032288 // myelin assembly // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043473 // pigmentation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // traceable author statement /// 0031902 // late endosome membrane // traceable author statement "0004438 // phosphatidylinositol-3-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034593 // phosphatidylinositol bisphosphate phosphatase activity // inferred from electronic annotation /// 0042578 // phosphoric ester hydrolase activity // inferred from electronic annotation /// 0043812 // phosphatidylinositol-4-phosphate phosphatase activity // inferred from electronic annotation /// 0043813 // phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity // traceable author statement" 203657_s_at NM_003793 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003793.2 /DEF=Homo sapiens cathepsin F (CTSF), mRNA. /FEA=mRNA /GEN=CTSF /PROD=cathepsin F /DB_XREF=gi:6042195 /UG=Hs.11590 cathepsin F /FL=gb:AF071748.1 gb:AF071749.1 gb:AF088886.2 gb:NM_003793.2 gb:AF136279.1" NM_003793 cathepsin F CTSF 8722 NM_003793 0006508 // proteolysis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement 0005764 // lysosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203658_at BC001689 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC001689.1 /DEF=Homo sapiens, carnitineacylcarnitine translocase, clone MGC:1207, mRNA, complete cds. /FEA=mRNA /PROD=carnitineacylcarnitine translocase /DB_XREF=gi:12804552 /UG=Hs.13845 solute carrier family 25 (carnitineacylcarnitine translocase), member 20 /FL=gb:BC001689.1 gb:NM_000387.2" BC001689 "solute carrier family 25 (carnitine/acylcarnitine translocase), member 20" SLC25A20 788 NM_000387 /// XM_006713327 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203659_s_at NM_005798 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005798.1 /DEF=Homo sapiens ret finger protein 2 (RFP2), mRNA. /FEA=mRNA /GEN=RFP2 /PROD=ret finger protein 2 /DB_XREF=gi:5031860 /UG=Hs.151428 ret finger protein 2 /FL=gb:AF220127.1 gb:AF220128.1 gb:NM_005798.1 gb:AF241850.1" NM_005798 tripartite motif containing 13 TRIM13 10206 NM_001007278 /// NM_005798 /// NM_052811 /// NM_213590 0007165 // signal transduction // inferred from mutant phenotype /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010332 // response to gamma radiation // inferred from expression pattern /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0016239 // positive regulation of macroautophagy // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097038 // perinuclear endoplasmic reticulum // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203660_s_at NM_006031 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006031.1 /DEF=Homo sapiens pericentrin (PCNT), mRNA. /FEA=mRNA /GEN=PCNT /PROD=pericentrin /DB_XREF=gi:5174478 /UG=Hs.15896 pericentrin /FL=gb:U52962.1 gb:NM_006031.1" NM_006031 pericentrin PCNT 5116 NM_006031 /// XM_005261124 /// XM_005261125 /// XM_005261126 /// XM_005261127 /// XM_005261128 /// XM_005261129 /// XM_005261130 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007051 // spindle organization // inferred from electronic annotation /// 0021696 // cerebellar cortex morphogenesis // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0061351 // neural precursor cell proliferation // inferred from electronic annotation /// 0090316 // positive regulation of intracellular protein transport // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0034451 // centriolar satellite // inferred from direct assay /// 0045171 // intercellular bridge // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 203661_s_at BC002660 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002660.1 /DEF=Homo sapiens, tropomodulin, clone MGC:3643, mRNA, complete cds. /FEA=mRNA /PROD=tropomodulin /DB_XREF=gi:12803650 /UG=Hs.170453 tropomodulin /FL=gb:BC002660.1 gb:M77016.1 gb:NM_003275.1" BC002660 tropomodulin 1 TMOD1 7111 NM_001166116 /// NM_003275 0006936 // muscle contraction // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030239 // myofibril assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 203662_s_at NM_003275 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003275.1 /DEF=Homo sapiens tropomodulin (TMOD), mRNA. /FEA=mRNA /GEN=TMOD /PROD=tropomodulin /DB_XREF=gi:4507552 /UG=Hs.170453 tropomodulin /FL=gb:BC002660.1 gb:M77016.1 gb:NM_003275.1" NM_003275 tropomodulin 1 TMOD1 7111 NM_001166116 /// NM_003275 0006936 // muscle contraction // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030239 // myofibril assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030016 // myofibril // inferred from electronic annotation /// 0030863 // cortical cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 203663_s_at NM_004255 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004255.1 /DEF=Homo sapiens cytochrome c oxidase subunit Va (COX5A), mRNA. /FEA=mRNA /GEN=COX5A /PROD=cytochrome c oxidase subunit Va /DB_XREF=gi:4758037 /UG=Hs.181028 cytochrome c oxidase subunit Va /FL=gb:NM_004255.1 gb:M22760.1" NM_004255 cytochrome c oxidase subunit Va COX5A 9377 NM_004255 0022904 // respiratory electron transport chain // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203664_s_at NM_004805 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004805.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide D (POLR2D), mRNA. /FEA=mRNA /GEN=POLR2D /PROD=polymerase (RNA) II (DNA directed) polypeptideD /DB_XREF=gi:4758573 /UG=Hs.194638 polymerase (RNA) II (DNA directed) polypeptide D /FL=gb:BC002958.1 gb:NM_004805.1" NM_004805 polymerase (RNA) II (DNA directed) polypeptide D POLR2D 5433 NM_004805 "0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // not recorded /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0031990 // mRNA export from nucleus in response to heat stress // not recorded /// 0034402 // recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex // not recorded /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045948 // positive regulation of translational initiation // not recorded /// 0050434 // positive regulation of viral transcription // traceable author statement" "0000932 // cytoplasmic mRNA processing body // not recorded /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // inferred from direct assay" 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // not recorded /// 0003727 // single-stranded RNA binding // not recorded /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from mutant phenotype /// 0031369 // translation initiation factor binding // not recorded 203665_at NM_002133 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002133.1 /DEF=Homo sapiens heme oxygenase (decycling) 1 (HMOX1), mRNA. /FEA=mRNA /GEN=HMOX1 /PROD=heme oxygenase (decyclizing) 1 /DB_XREF=gi:4504436 /UG=Hs.202833 heme oxygenase (decycling) 1 /FL=gb:NM_002133.1" NM_002133 heme oxygenase (decycling) 1 HMOX1 3162 NM_002133 0001525 // angiogenesis // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // traceable author statement /// 0002246 // wound healing involved in inflammatory response // inferred from mutant phenotype /// 0002686 // negative regulation of leukocyte migration // traceable author statement /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006788 // heme oxidation // inferred from direct assay /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007588 // excretion // inferred by curator /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0010656 // negative regulation of muscle cell apoptotic process // inferred from electronic annotation /// 0014806 // smooth muscle hyperplasia // traceable author statement /// 0031670 // cellular response to nutrient // inferred from electronic annotation /// 0032764 // negative regulation of mast cell cytokine production // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0034383 // low-density lipoprotein particle clearance // traceable author statement /// 0035094 // response to nicotine // inferred from direct assay /// 0035556 // intracellular signal transduction // traceable author statement /// 0042167 // heme catabolic process // inferred from direct assay /// 0042167 // heme catabolic process // traceable author statement /// 0042168 // heme metabolic process // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043305 // negative regulation of mast cell degranulation // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from electronic annotation /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045080 // positive regulation of chemokine biosynthetic process // traceable author statement /// 0045765 // regulation of angiogenesis // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0045909 // positive regulation of vasodilation // inferred by curator /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from direct assay /// 0055072 // iron ion homeostasis // inferred from direct assay /// 0055072 // iron ion homeostasis // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071243 // cellular response to arsenic-containing substance // inferred from electronic annotation /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004392 // heme oxygenase (decyclizing) activity // inferred from direct assay /// 0004392 // heme oxygenase (decyclizing) activity // inferred from mutant phenotype /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from sequence or structural similarity /// 0020037 // heme binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203666_at NM_000609 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000609.1 /DEF=Homo sapiens stromal cell-derived factor 1 (SDF1), mRNA. /FEA=mRNA /GEN=SDF1 /PROD=stromal cell-derived factor 1 /DB_XREF=gi:10834987 /UG=Hs.237356 stromal cell-derived factor 1 /FL=gb:NM_000609.1 gb:L36033.1 gb:U16752.1" NM_000609 chemokine (C-X-C motif) ligand 12 CXCL12 6387 NM_000609 /// NM_001033886 /// NM_001178134 /// NM_001277990 /// NM_199168 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008064 // regulation of actin polymerization or depolymerization // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0090280 // positive regulation of calcium ion import // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042379 // chemokine receptor binding // inferred from mutant phenotype /// 0045236 // CXCR chemokine receptor binding // inferred from direct assay 203667_at NM_004607 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004607.1 /DEF=Homo sapiens tubulin-specific chaperone a (TBCA), mRNA. /FEA=mRNA /GEN=TBCA /PROD=beta-tubulin cofactor A /DB_XREF=gi:4759211 /UG=Hs.24930 tubulin-specific chaperone a /FL=gb:AF038952.1 gb:NM_004607.1" NM_004607 tubulin folding cofactor A TBCA 6902 NM_004607 /// XM_005248586 0006457 // protein folding // traceable author statement /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0007023 // post-chaperonin tubulin folding pathway // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 203668_at NM_006715 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006715.1 /DEF=Homo sapiens mannosidase, alpha, class 2C, member 1 (MAN2C1), mRNA. /FEA=mRNA /GEN=MAN2C1 /PROD=mannosidase, alpha 6A8 /DB_XREF=gi:6631092 /UG=Hs.26232 mannosidase, alpha, class 2C, member 1 /FL=gb:U37248.1 gb:AF044414.2 gb:NM_006715.1" NM_006715 "mannosidase, alpha, class 2C, member 1" MAN2C1 4123 NM_001256494 /// NM_001256495 /// NM_001256496 /// NM_006715 /// XM_005254384 /// XM_006720508 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006013 // mannose metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004559 // alpha-mannosidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015923 // mannosidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203669_s_at NM_012079 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012079.2 /DEF=Homo sapiens diacylglycerol O-acyltransferase (mouse) homolog (DGAT), mRNA. /FEA=mRNA /GEN=DGAT /PROD=diacylglycerol O-acyltransferase (mouse)homolog /DB_XREF=gi:7382489 /UG=Hs.288627 diacylglycerol O-acyltransferase (mouse) homolog /FL=gb:AF059202.1 gb:NM_012079.2" NM_012079 diacylglycerol O-acyltransferase 1 DGAT1 8694 NM_012079 0006641 // triglyceride metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0019915 // lipid storage // inferred from sequence or structural similarity /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0035336 // long-chain fatty-acyl-CoA metabolic process // inferred from sequence or structural similarity /// 0036155 // acylglycerol acyl-chain remodeling // traceable author statement /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046339 // diacylglycerol metabolic process // inferred from sequence or structural similarity /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0046486 // glycerolipid metabolic process // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0003846 // 2-acylglycerol O-acyltransferase activity // inferred from electronic annotation /// 0004144 // diacylglycerol O-acyltransferase activity // not recorded /// 0004144 // diacylglycerol O-acyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008374 // O-acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // traceable author statement /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050252 // retinol O-fatty-acyltransferase activity // inferred from electronic annotation" 203670_at NM_015644 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015644.1 /DEF=Homo sapiens DKFZP434B103 protein (DKFZP434B103), mRNA. /FEA=mRNA /GEN=DKFZP434B103 /PROD=DKFZP434B103 protein /DB_XREF=gi:7661563 /UG=Hs.289010 DKFZP434B103 protein /FL=gb:NM_015644.1" NM_015644 "actin related protein 2/3 complex, subunit 4, 20kDa /// ARPC4-TTLL3 readthrough /// tubulin tyrosine ligase-like family, member 3" ARPC4 /// ARPC4-TTLL3 /// TTLL3 10093 /// 26140 /// 100526693 NM_001024959 /// NM_001024960 /// NM_001025930 /// NM_001198780 /// NM_001198793 /// NM_005718 /// NM_015644 /// NR_037162 0006464 // cellular protein modification process // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0018094 // protein polyglycylation // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from electronic annotation /// 0034314 // Arp2/3 complex-mediated actin nucleation // inferred from electronic annotation /// 0035082 // axoneme assembly // inferred from sequence or structural similarity /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0042384 // cilium assembly // inferred from sequence or structural similarity /// 0045010 // actin nucleation // non-traceable author statement /// 0045087 // innate immune response // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // inferred from direct assay /// 0005929 // cilium // inferred from sequence or structural similarity /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from physical interaction /// 0051015 // actin filament binding // non-traceable author statement /// 0070735 // protein-glycine ligase activity // inferred from direct assay /// 0070736 // protein-glycine ligase activity, initiating // inferred from sequence or structural similarity" 203671_at BF196891 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF196891 /FEA=EST /DB_XREF=gi:11085421 /DB_XREF=est:7l79g03.x1 /CLONE=IMAGE:3527621 /UG=Hs.296922 thiopurine S-methyltransferase /FL=gb:BC005339.1 gb:NM_000367.1 gb:U12387.1 BF196891 thiopurine S-methyltransferase TPMT 7172 NM_000367 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0033574 // response to testosterone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008119 // thiopurine S-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203672_x_at U12387 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U12387.1 /DEF=Human thiopurine methyltransferase (TPMT) mRNA, complete cds. /FEA=mRNA /GEN=TPMT /PROD=thiopurine methyltransferase /DB_XREF=gi:805083 /UG=Hs.296922 thiopurine S-methyltransferase /FL=gb:BC005339.1 gb:NM_000367.1 gb:U12387.1" U12387 thiopurine S-methyltransferase TPMT 7172 NM_000367 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032259 // methylation // traceable author statement /// 0033574 // response to testosterone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008119 // thiopurine S-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008757 // S-adenosylmethionine-dependent methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203673_at NM_003235 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003235.2 /DEF=Homo sapiens thyroglobulin (TG), mRNA. /FEA=mRNA /GEN=TG /PROD=thyroglobulin /DB_XREF=gi:6631113 /UG=Hs.305916 thyroglobulin /FL=gb:U93033.2 gb:NM_003235.2" NM_003235 thyroglobulin TG 7038 NM_003235 /// XM_005251038 /// XM_005251040 /// XM_005251042 /// XM_005251043 /// XM_006716622 /// XM_006716623 0006590 // thyroid hormone generation // not recorded /// 0007165 // signal transduction // non-traceable author statement /// 0007416 // synapse assembly // not recorded /// 0015705 // iodide transport // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from expression pattern /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0042403 // thyroid hormone metabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005615 // extracellular space // not recorded /// 0005887 // integral component of plasma membrane // not recorded /// 0009986 // cell surface // not recorded /// 0045202 // synapse // not recorded 0004872 // receptor activity // not recorded /// 0005179 // hormone activity // inferred from electronic annotation /// 0042043 // neurexin family protein binding // not recorded 203674_at NM_014877 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014877.1 /DEF=Homo sapiens KIAA0054 gene product; Helicase (KIAA0054), mRNA. /FEA=mRNA /GEN=KIAA0054 /PROD=KIAA0054 gene product; Helicase /DB_XREF=gi:7661883 /UG=Hs.3085 KIAA0054 gene product; Helicase /FL=gb:D29677.1 gb:NM_014877.1" NM_014877 helicase with zinc finger HELZ 9931 NM_014877 /// XM_005257888 /// XM_005257889 /// XM_005257890 /// XM_006722214 /// XM_006722215 /// XM_006722216 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203675_at NM_005013 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005013.1 /DEF=Homo sapiens nucleobindin 2 (NUCB2), mRNA. /FEA=mRNA /GEN=NUCB2 /PROD=nucleobindin 2 /DB_XREF=gi:4826869 /UG=Hs.3164 nucleobindin 2 /FL=gb:AF052642.1 gb:AF052643.1 gb:AF052644.1 gb:NM_005013.1" NM_005013 nucleobindin 2 NUCB2 4925 NM_005013 /// XM_005252941 /// XM_005252942 /// XM_005252943 /// XM_005252944 /// XM_005252945 /// XM_005252947 /// XM_005252948 /// XM_006718239 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203676_at NM_002076 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002076.1 /DEF=Homo sapiens glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) (GNS), mRNA. /FEA=mRNA /GEN=GNS /PROD=glucosamine (N-acetyl)-6-sulfatase precursor /DB_XREF=gi:4504060 /UG=Hs.321070 glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) /FL=gb:NM_002076.1" NM_002076 glucosamine (N-acetyl)-6-sulfatase GNS 2799 NM_002076 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008449 // N-acetylglucosamine-6-sulfatase activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203677_s_at NM_004178 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004178.2 /DEF=Homo sapiens TAR (HIV) RNA-binding protein 2 (TARBP2), mRNA. /FEA=mRNA /GEN=TARBP2 /PROD=TAR (HIV) RNA-binding protein 2 /DB_XREF=gi:7427525 /UG=Hs.326 TAR (HIV) RNA-binding protein 2 /FL=gb:U08998.2 gb:NM_004178.2" NM_004178 TAR (HIV-1) RNA binding protein 2 TARBP2 6895 NM_004178 /// NM_134323 /// NM_134324 /// XM_005269114 /// XM_005269115 /// XM_005269116 /// XM_005269117 /// XM_005269120 /// XM_005269122 /// XM_006719581 /// XR_245955 "0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030422 // production of siRNA involved in RNA interference // inferred from direct assay /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0031054 // pre-miRNA processing // inferred from direct assay /// 0035280 // miRNA loading onto RISC involved in gene silencing by miRNA // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from direct assay /// 0046782 // regulation of viral transcription // inferred from direct assay /// 0050689 // negative regulation of defense response to virus by host // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016442 // RISC complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0035197 // siRNA binding // inferred from direct assay /// 0035198 // miRNA binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 203678_at NM_014967 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014967.1 /DEF=Homo sapiens KIAA1018 protein (KIAA1018), mRNA. /FEA=mRNA /GEN=KIAA1018 /PROD=KIAA1018 protein /DB_XREF=gi:7662449 /UG=Hs.5400 KIAA1018 protein /FL=gb:AB023235.1 gb:NM_014967.1" NM_014967 FANCD2/FANCI-associated nuclease 1 FAN1 22909 NM_001146094 /// NM_001146095 /// NM_001146096 /// NM_014967 /// XM_005254232 /// XM_005254233 /// XM_005254234 /// XM_005254235 /// XM_005254236 /// XM_006725537 /// XM_006725538 /// XM_006725539 /// XM_006725540 /// XM_006725541 "0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0033683 // nucleotide-excision repair, DNA incision // inferred from direct assay /// 0033683 // nucleotide-excision repair, DNA incision // inferred from mutant phenotype" 0005634 // nucleus // inferred from direct assay "0000287 // magnesium ion binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004528 // phosphodiesterase I activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008409 // 5'-3' exonuclease activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0017108 // 5'-flap endonuclease activity // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203679_at NM_006858 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006858.1 /DEF=Homo sapiens putative T1ST2 receptor binding protein (IL1RL1LG), mRNA. /FEA=mRNA /GEN=IL1RL1LG /PROD=putative T1ST2 receptor binding protein /DB_XREF=gi:5803039 /UG=Hs.54411 putative T1ST2 receptor binding protein /FL=gb:U41804.1 gb:BC002443.1 gb:NM_006858.1" NM_006858 transmembrane emp24 protein transport domain containing 1 TMED1 11018 NM_006858 /// NR_104015 /// XM_006722631 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203680_at NM_002736 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002736.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B), mRNA. /FEA=mRNA /GEN=PRKAR2B /PROD=protein kinase, cAMP-dependent, regulatory, typeII, beta /DB_XREF=gi:4506064 /UG=Hs.77439 protein kinase, cAMP-dependent, regulatory, type II, beta /FL=gb:M31158.1 gb:NM_002736.1" NM_002736 "protein kinase, cAMP-dependent, regulatory, type II, beta" PRKAR2B 5577 NM_002736 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 0097332 // response to antipsychotic drug // inferred from electronic annotation /// 0097338 // response to clozapine // inferred from electronic annotation /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from direct assay /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction 203681_at M34192 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:M34192.1 /DEF=Human isovaleryl-coA dehydrogenase (IVD) mRNA, complete cds. /FEA=mRNA /GEN=IVD /DB_XREF=gi:184538 /UG=Hs.77510 isovaleryl Coenzyme A dehydrogenase /FL=gb:M34192.1 gb:NM_002225.2" M34192 isovaleryl-CoA dehydrogenase IVD 3712 NM_001159508 /// NM_002225 /// XM_005254350 /// XM_005254356 /// XM_006720491 /// XM_006720492 /// XM_006720493 /// XM_006720494 /// XM_006720495 /// XR_243097 /// XR_243098 /// XR_429453 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement "0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0008470 // isovaleryl-CoA dehydrogenase activity // not recorded /// 0008470 // isovaleryl-CoA dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 203682_s_at NM_002225 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002225.2 /DEF=Homo sapiens isovaleryl Coenzyme A dehydrogenase (IVD), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=IVD /PROD=isovaleryl Coenzyme A dehydrogenase /DB_XREF=gi:6031167 /UG=Hs.77510 isovaleryl Coenzyme A dehydrogenase /FL=gb:M34192.1 gb:NM_002225.2" NM_002225 isovaleryl-CoA dehydrogenase IVD 3712 NM_001159508 /// NM_002225 /// XM_005254350 /// XM_005254356 /// XM_006720491 /// XM_006720492 /// XM_006720493 /// XM_006720494 /// XM_006720495 /// XR_243097 /// XR_243098 /// XR_429453 0006552 // leucine catabolic process // inferred from electronic annotation /// 0006552 // leucine catabolic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation "0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0008470 // isovaleryl-CoA dehydrogenase activity // not recorded /// 0008470 // isovaleryl-CoA dehydrogenase activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 203683_s_at NM_003377 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003377.1 /DEF=Homo sapiens vascular endothelial growth factor B (VEGFB), mRNA. /FEA=mRNA /GEN=VEGFB /PROD=vascular endothelial growth factor B /DB_XREF=gi:4507886 /UG=Hs.78781 vascular endothelial growth factor B /FL=gb:U43368.1 gb:U52819.1 gb:NM_003377.1" NM_003377 vascular endothelial growth factor B VEGFB 7423 NM_001243733 /// NM_003377 0001525 // angiogenesis // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0035470 // positive regulation of vascular wound healing // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043117 // positive regulation of vascular permeability // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060754 // positive regulation of mast cell chemotaxis // inferred from direct assay /// 0060976 // coronary vasculature development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043183 // vascular endothelial growth factor receptor 1 binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203684_s_at M13994 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M13994.1 /DEF=Human B-cell leukemialymphoma 2 (bcl-2) proto-oncogene mRNA encoding bcl-2-alpha protein, complete cds. /FEA=mRNA /GEN=BCL2 /DB_XREF=gi:179366 /UG=Hs.79241 B-cell CLLlymphoma 2 /FL=gb:M13994.1 gb:NM_000633.1" M13994 B-cell CLL/lymphoma 2 BCL2 596 NM_000633 /// NM_000657 /// XM_006722523 /// XR_430082 "0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001101 // response to acid // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // non-traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from direct assay /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032835 // glomerulus development // inferred from electronic annotation /// 0032848 // negative regulation of cellular pH reduction // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043375 // CD8-positive, alpha-beta T cell lineage commitment // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046671 // negative regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051902 // negative regulation of mitochondrial depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0002020 // protease binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from direct assay /// 0016248 // channel inhibitor activity // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from electronic annotation 203685_at NM_000633 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000633.1 /DEF=Homo sapiens B-cell CLLlymphoma 2 (BCL2), nuclear gene encoding mitochondrial protein, transcript variant alpha, mRNA. /FEA=mRNA /GEN=BCL2 /PROD=B-cell lymphoma protein 2 alpha /DB_XREF=gi:4557354 /UG=Hs.79241 B-cell CLLlymphoma 2 /FL=gb:M13994.1 gb:NM_000633.1" NM_000633 B-cell CLL/lymphoma 2 BCL2 596 NM_000633 /// NM_000657 /// XM_006722523 /// XR_430082 "0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001101 // response to acid // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // non-traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from direct assay /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032835 // glomerulus development // inferred from electronic annotation /// 0032848 // negative regulation of cellular pH reduction // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043375 // CD8-positive, alpha-beta T cell lineage commitment // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046671 // negative regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051902 // negative regulation of mitochondrial depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0002020 // protease binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from direct assay /// 0016248 // channel inhibitor activity // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from electronic annotation 203686_at NM_002434 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002434.1 /DEF=Homo sapiens N-methylpurine-DNA glycosylase (MPG), mRNA. /FEA=mRNA /GEN=MPG /PROD=N-methylpurine-DNA glycosylase /DB_XREF=gi:4505232 /UG=Hs.79396 N-methylpurine-DNA glycosylase /FL=gb:M74905.1 gb:L10752.1 gb:NM_002434.1" NM_002434 N-methylpurine-DNA glycosylase MPG 4350 NM_001015052 /// NM_001015054 /// NM_002434 "0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // not recorded /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006307 // DNA dealkylation involved in DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0045007 // depurination // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003905 // alkylbase DNA N-glycosylase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008725 // DNA-3-methyladenine glycosylase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043916 // DNA-7-methylguanine glycosylase activity // inferred from electronic annotation /// 0052821 // DNA-7-methyladenine glycosylase activity // inferred from electronic annotation /// 0052822 // DNA-3-methylguanine glycosylase activity // inferred from electronic annotation 203687_at NM_002996 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002996.1 /DEF=Homo sapiens small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) (SCYD1), mRNA. /FEA=mRNA /GEN=SCYD1 /PROD=small inducible cytokine subfamily D(Cys-X3-Cys), member 1 (fractalkine, neurotactin) /DB_XREF=gi:4506856 /UG=Hs.80420 small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) /FL=gb:BC001163.1 gb:U84487.1 gb:U91835.1 gb:NM_002996.1" NM_002996 chemokine (C-X3-C motif) ligand 1 CX3CL1 6376 NM_002996 0006935 // chemotaxis // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0030595 // leukocyte chemotaxis // traceable author statement /// 0032914 // positive regulation of transforming growth factor beta1 production // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from electronic annotation /// 0048247 // lymphocyte chemotaxis // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from expression pattern /// 0050902 // leukocyte adhesive activation // traceable author statement /// 0051041 // positive regulation of calcium-independent cell-cell adhesion // inferred from direct assay /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0008009 // chemokine activity // traceable author statement 203688_at NM_000297 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000297.1 /DEF=Homo sapiens polycystic kidney disease 2 (autosomal dominant) (PKD2), mRNA. /FEA=mRNA /GEN=PKD2 /PROD=polycystin 2 /DB_XREF=gi:4505834 /UG=Hs.82001 polycystic kidney disease 2 (autosomal dominant) /FL=gb:U50928.1 gb:NM_000297.1" NM_000297 polycystic kidney disease 2 (autosomal dominant) PKD2 5311 NM_000297 /// XR_244632 "0001658 // branching involved in ureteric bud morphogenesis // inferred from expression pattern /// 0001822 // kidney development // inferred from electronic annotation /// 0001889 // liver development // inferred from expression pattern /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0001947 // heart looping // inferred from mutant phenotype /// 0003127 // detection of nodal flow // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from expression pattern /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from expression pattern /// 0021915 // neural tube development // inferred from expression pattern /// 0030814 // regulation of cAMP metabolic process // inferred from sequence or structural similarity /// 0031587 // positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from mutant phenotype /// 0031659 // positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // non-traceable author statement /// 0035502 // metanephric part of ureteric bud development // inferred from expression pattern /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0035904 // aorta development // inferred from expression pattern /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from mutant phenotype /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0050982 // detection of mechanical stimulus // not recorded /// 0050982 // detection of mechanical stimulus // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from mutant phenotype /// 0051298 // centrosome duplication // non-traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060315 // negative regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060674 // placenta blood vessel development // inferred from sequence or structural similarity /// 0061333 // renal tubule morphogenesis // inferred from sequence or structural similarity /// 0061441 // renal artery morphogenesis // inferred from expression pattern /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from mutant phenotype /// 0071464 // cellular response to hydrostatic pressure // inferred from direct assay /// 0071470 // cellular response to osmotic stress // inferred from direct assay /// 0071498 // cellular response to fluid shear stress // inferred from mutant phenotype /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 0071910 // determination of liver left/right asymmetry // inferred from mutant phenotype /// 0072001 // renal system development // inferred from electronic annotation /// 0072075 // metanephric mesenchyme development // inferred from expression pattern /// 0072164 // mesonephric tubule development // inferred from expression pattern /// 0072177 // mesonephric duct development // inferred from expression pattern /// 0072208 // metanephric smooth muscle tissue development // inferred from expression pattern /// 0072214 // metanephric cortex development // inferred from expression pattern /// 0072218 // metanephric ascending thin limb development // inferred from expression pattern /// 0072219 // metanephric cortical collecting duct development // inferred from expression pattern /// 0072235 // metanephric distal tubule development // inferred from expression pattern /// 0072284 // metanephric S-shaped body morphogenesis // inferred from expression pattern /// 0090279 // regulation of calcium ion import // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from mutant phenotype" 0002133 // polycystin complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from sequence or structural similarity /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045180 // basal cortex // inferred from direct assay /// 0060170 // ciliary membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071458 // integral component of cytoplasmic side of endoplasmic reticulum membrane // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay 0005102 // receptor binding // inferred from physical interaction /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from direct assay /// 0005245 // voltage-gated calcium channel activity // inferred from direct assay /// 0005248 // voltage-gated sodium channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015267 // channel activity // inferred from electronic annotation /// 0022843 // voltage-gated cation channel activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042805 // actinin binding // inferred from direct assay /// 0043398 // HLH domain binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048763 // calcium-induced calcium release activity // inferred from direct assay /// 0051117 // ATPase binding // inferred from sequence or structural similarity /// 0051219 // phosphoprotein binding // inferred from physical interaction /// 0051371 // muscle alpha-actinin binding // inferred from electronic annotation /// 0051393 // alpha-actinin binding // inferred from electronic annotation 203689_s_at AI743037 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI743037 /FEA=EST /DB_XREF=gi:5111325 /DB_XREF=est:wg85d05.x1 /CLONE=IMAGE:2371881 /UG=Hs.89764 fragile X mental retardation 1 /FL=gb:NM_002024.1 AI743037 fragile X mental retardation 1 FMR1 2332 NM_001185075 /// NM_001185076 /// NM_001185081 /// NM_001185082 /// NM_002024 /// NR_033699 /// NR_033700 0006810 // transport // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0045947 // negative regulation of translational initiation // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005845 // mRNA cap binding complex // inferred from sequence or structural similarity /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042788 // polysomal ribosome // traceable author statement /// 0043005 // neuron projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0071598 // neuronal ribonucleoprotein granule // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203690_at NM_006322 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006322.1 /DEF=Homo sapiens spindle pole body protein (GCP3), mRNA. /FEA=mRNA /GEN=GCP3 /PROD=spindle pole body protein /DB_XREF=gi:5453659 /UG=Hs.9884 spindle pole body protein /FL=gb:AF042378.1 gb:NM_006322.1" NM_006322 "tubulin, gamma complex associated protein 3" TUBGCP3 10426 NM_001286277 /// NM_001286278 /// NM_001286279 /// NM_006322 /// XM_005268293 /// XR_245841 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007020 // microtubule nucleation // non-traceable author statement /// 0007338 // single fertilization // non-traceable author statement 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // non-traceable author statement /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // non-traceable author statement /// 0005827 // polar microtubule // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005198 // structural molecule activity // non-traceable author statement /// 0005200 // structural constituent of cytoskeleton // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043015 // gamma-tubulin binding // inferred from direct assay 203691_at NM_002638 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002638.1 /DEF=Homo sapiens protease inhibitor 3, skin-derived (SKALP) (PI3), mRNA. /FEA=mRNA /GEN=PI3 /PROD=protease inhibitor 3, skin-derived (SKALP) /DB_XREF=gi:4505786 /UG=Hs.112341 protease inhibitor 3, skin-derived (SKALP) /FL=gb:NM_002638.1" NM_002638 "peptidase inhibitor 3, skin-derived" PI3 5266 NM_002638 0007620 // copulation // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 203692_s_at AI640363 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI640363 /FEA=EST /DB_XREF=gi:4703472 /DB_XREF=est:wa17d03.x1 /CLONE=IMAGE:2298341 /UG=Hs.1189 E2F transcription factor 3 /FL=gb:NM_001949.2 AI640363 E2F transcription factor 3 E2F3 1871 NM_001243076 /// NM_001949 /// XM_005248865 /// XM_005248866 /// XM_005248868 "0000085 // mitotic G2 phase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203693_s_at NM_001949 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001949.2 /DEF=Homo sapiens E2F transcription factor 3 (E2F3) mRNA, complete cds. /FEA=mRNA /GEN=E2F3 /PROD=E2F transcription factor 3 /DB_XREF=gi:12669913 /UG=Hs.1189 E2F transcription factor 3 /FL=gb:NM_001949.2" NM_001949 E2F transcription factor 3 E2F3 1871 NM_001243076 /// NM_001949 /// XM_005248865 /// XM_005248866 /// XM_005248868 "0000085 // mitotic G2 phase // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0001047 // core promoter binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203694_s_at NM_003587 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003587.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 16 (DDX16), mRNA. /FEA=mRNA /GEN=DDX16 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 16 /DB_XREF=gi:13787201 /UG=Hs.12797 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 16 /FL=gb:NM_003587.2 gb:AB011149.1 gb:AB001601.1" NM_003587 DEAH (Asp-Glu-Ala-His) box polypeptide 16 DHX16 8449 NM_001164239 /// NM_003587 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203695_s_at NM_004403 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004403.1 /DEF=Homo sapiens deafness, autosomal dominant 5 (DFNA5), mRNA. /FEA=mRNA /GEN=DFNA5 /PROD=deafness, autosomal dominant 5 protein /DB_XREF=gi:4758153 /UG=Hs.13530 deafness, autosomal dominant 5 /FL=gb:AF073308.1 gb:NM_004403.1 gb:AF007790.2" NM_004403 "deafness, autosomal dominant 5" DFNA5 1687 NM_001127453 /// NM_001127454 /// NM_004403 0006915 // apoptotic process // inferred from electronic annotation /// 0007605 // sensory perception of sound // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay 203696_s_at NM_002914 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002914.1 /DEF=Homo sapiens replication factor C (activator 1) 2 (40kD) (RFC2), mRNA. /FEA=mRNA /GEN=RFC2 /PROD=replication factor C (activator 1) 2 (40kD) /DB_XREF=gi:4506486 /UG=Hs.139226 replication factor C (activator 1) 2 (40kD) /FL=gb:M87338.1 gb:NM_002914.1" NM_002914 "replication factor C (activator 1) 2, 40kDa" RFC2 5982 NM_001278791 /// NM_001278792 /// NM_001278793 /// NM_002914 /// NM_181471 /// XM_006716080 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016851 // magnesium chelatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 203697_at U91903 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U91903.1 /DEF=Human Fritz mRNA, complete cds. /FEA=mRNA /PROD=Fritz /DB_XREF=gi:1917006 /UG=Hs.153684 frizzled-related protein /FL=gb:U24163.1 gb:U68057.1 gb:U91903.1 gb:NM_001463.1" U91903 frizzled-related protein FRZB 2487 NM_001463 0001501 // skeletal system development // traceable author statement /// 0001944 // vasculature development // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0010721 // negative regulation of cell development // inferred from electronic annotation /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0061037 // negative regulation of cartilage development // not recorded /// 0061053 // somite development // inferred from electronic annotation /// 0070367 // negative regulation of hepatocyte differentiation // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0016020 // membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 203698_s_at NM_001463 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001463.1 /DEF=Homo sapiens frizzled-related protein (FRZB), mRNA. /FEA=mRNA /GEN=FRZB /PROD=frizzled-related protein /DB_XREF=gi:4503788 /UG=Hs.153684 frizzled-related protein /FL=gb:U24163.1 gb:U68057.1 gb:U91903.1 gb:NM_001463.1" NM_001463 frizzled-related protein FRZB 2487 NM_001463 0001501 // skeletal system development // traceable author statement /// 0001944 // vasculature development // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008406 // gonad development // not recorded /// 0010721 // negative regulation of cell development // inferred from electronic annotation /// 0014033 // neural crest cell differentiation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0030178 // negative regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from genetic interaction /// 0045600 // positive regulation of fat cell differentiation // inferred from direct assay /// 0060029 // convergent extension involved in organogenesis // inferred from electronic annotation /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0061037 // negative regulation of cartilage development // not recorded /// 0061053 // somite development // inferred from electronic annotation /// 0070367 // negative regulation of hepatocyte differentiation // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090103 // cochlea morphogenesis // not recorded 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0016020 // membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 203699_s_at U53506 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U53506.1 /DEF=Human type II iodothyronine deiodinase mRNA, complete cds. /FEA=mRNA /PROD=type II iodothyronine deiodinase /DB_XREF=gi:1518541 /UG=Hs.154424 deiodinase, iodothyronine, type II /FL=gb:U53506.1 gb:AF093774.1 gb:NM_013989.1" U53506 "deiodinase, iodothyronine, type II" DIO2 1734 NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989 0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203700_s_at NM_013989 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013989.1 /DEF=Homo sapiens deiodinase, iodothyronine, type II (DIO2), transcript variant 1, mRNA. /FEA=mRNA /GEN=DIO2 /PROD=deiodinase, iodothyronine, type II /DB_XREF=gi:7549802 /UG=Hs.154424 deiodinase, iodothyronine, type II /FL=gb:U53506.1 gb:AF093774.1 gb:NM_013989.1" NM_013989 "deiodinase, iodothyronine, type II" DIO2 1734 NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989 0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation 0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203701_s_at NM_017722 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017722.1 /DEF=Homo sapiens hypothetical protein FLJ20244 (FLJ20244), mRNA. /FEA=mRNA /GEN=FLJ20244 /PROD=hypothetical protein FLJ20244 /DB_XREF=gi:8923218 /UG=Hs.158947 hypothetical protein FLJ20244 /FL=gb:AF196479.1 gb:NM_017722.1" NM_017722 tRNA methyltransferase 1 homolog (S. cerevisiae) TRMT1 55621 NM_001136035 /// NM_001142554 /// NM_017722 /// XM_005259983 /// XM_006722793 /// XM_006722794 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004809 // tRNA (guanine-N2-)-methyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203702_s_at AL043927 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL043927 /FEA=EST /DB_XREF=gi:5935917 /DB_XREF=est:DKFZp434F1028_s1 /CLONE=DKFZp434F1028 /UG=Hs.169910 KIAA0173 gene product /FL=gb:D79995.1 gb:NM_014640.1 AL043927 "tubulin tyrosine ligase-like family, member 4" TTLL4 9654 NM_014640 /// XM_005246977 /// XM_005246978 /// XM_006712873 /// XM_006712874 /// XM_006712875 /// XM_006712876 0006464 // cellular protein modification process // inferred from electronic annotation /// 0018095 // protein polyglutamylation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0015631 // tubulin binding // inferred from sequence or structural similarity /// 0016874 // ligase activity // inferred from electronic annotation 203703_s_at NM_014640 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014640.1 /DEF=Homo sapiens KIAA0173 gene product (KIAA0173), mRNA. /FEA=mRNA /GEN=KIAA0173 /PROD=KIAA0173 gene product /DB_XREF=gi:7661969 /UG=Hs.169910 KIAA0173 gene product /FL=gb:D79995.1 gb:NM_014640.1" NM_014640 "tubulin tyrosine ligase-like family, member 4" TTLL4 9654 NM_014640 /// XM_005246977 /// XM_005246978 /// XM_006712873 /// XM_006712874 /// XM_006712875 /// XM_006712876 0006464 // cellular protein modification process // inferred from electronic annotation /// 0018095 // protein polyglutamylation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0015631 // tubulin binding // inferred from sequence or structural similarity /// 0016874 // ligase activity // inferred from electronic annotation 203704_s_at AW118862 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW118862 /FEA=EST /DB_XREF=gi:6087446 /DB_XREF=est:xd97e12.x1 /CLONE=IMAGE:2605582 /UG=Hs.171942 ras responsive element binding protein 1 /FL=gb:U26914.1 gb:D49835.1 gb:NM_002955.1 AW118862 ras responsive element binding protein 1 RREB1 6239 NM_001003698 /// NM_001003699 /// NM_001003700 /// NM_001168344 /// NM_002955 /// XM_005249272 /// XM_005249275 /// XM_005249276 /// XM_006715156 /// XM_006715157 /// XM_006715158 /// XM_006715159 /// XM_006715160 /// XM_006715161 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0016604 // nuclear body // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203705_s_at AI333651 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI333651 /FEA=EST /DB_XREF=gi:4070210 /DB_XREF=est:qq08e12.x1 /CLONE=IMAGE:1931950 /UG=Hs.173859 frizzled (Drosophila) homolog 7 /FL=gb:AB010881.1 gb:AB017365.1 gb:NM_003507.1 AI333651 frizzled class receptor 7 FZD7 8324 NM_003507 "0001944 // vasculature development // not recorded /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0010812 // negative regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042666 // negative regulation of ectodermal cell fate specification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred by curator /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060231 // mesenchymal to epithelial transition // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity" 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 203706_s_at NM_003507 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003507.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 7 (FZD7), mRNA. /FEA=mRNA /GEN=FZD7 /PROD=frizzled 7 /DB_XREF=gi:4503832 /UG=Hs.173859 frizzled (Drosophila) homolog 7 /FL=gb:AB010881.1 gb:AB017365.1 gb:NM_003507.1" NM_003507 frizzled class receptor 7 FZD7 8324 NM_003507 "0001944 // vasculature development // not recorded /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0010812 // negative regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042666 // negative regulation of ectodermal cell fate specification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred by curator /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060231 // mesenchymal to epithelial transition // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity" 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005109 // frizzled binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded 203707_at NM_005741 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005741.1 /DEF=Homo sapiens zinc finger protein 263 (ZNF263), mRNA. /FEA=mRNA /GEN=ZNF263 /PROD=zinc finger protein 263 /DB_XREF=gi:5032240 /UG=Hs.182528 zinc finger protein 263 /FL=gb:D88827.1 gb:NM_005741.1" NM_005741 long intergenic non-protein coding RNA 921 /// zinc finger protein 263 LINC00921 /// ZNF263 10127 /// 283876 NM_005741 /// NR_033904 /// XM_005255031 /// XM_006720831 /// XM_006720832 /// XM_006720833 /// XM_006720834 /// XM_006720835 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203708_at NM_002600 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002600.1 /DEF=Homo sapiens phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4) (PDE4B), mRNA. /FEA=mRNA /GEN=PDE4B /PROD=phosphodiesterase 4B, cAMP-specific (dunce(Drosophila)-homolog phosphodiesterase E4) /DB_XREF=gi:4505662 /UG=Hs.188 phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4) /FL=gb:M97515.1 gb:L20971.1 gb:NM_002600.1" NM_002600 "phosphodiesterase 4B, cAMP-specific" PDE4B 5142 NM_001037339 /// NM_001037340 /// NM_001037341 /// NM_001297440 /// NM_001297441 /// NM_001297442 /// NM_002600 /// XM_005270923 /// XM_005270924 /// XM_005270925 /// XM_005270926 /// XM_006710680 0001780 // neutrophil homeostasis // inferred from sequence or structural similarity /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from electronic annotation /// 0006198 // cAMP catabolic process // inferred from genetic interaction /// 0007165 // signal transduction // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from sequence or structural similarity /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0032743 // positive regulation of interleukin-2 production // inferred from mutant phenotype /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0050900 // leukocyte migration // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from sequence or structural similarity /// 0071872 // cellular response to epinephrine stimulus // inferred from sequence or structural similarity /// 0086004 // regulation of cardiac muscle cell contraction // inferred from sequence or structural similarity /// 1901841 // regulation of high voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1901898 // negative regulation of relaxation of cardiac muscle // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from sequence or structural similarity /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation "0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from sequence or structural similarity /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from direct assay /// 0004115 // 3',5'-cyclic-AMP phosphodiesterase activity // inferred from genetic interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from genetic interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation" 203709_at NM_000294 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000294.1 /DEF=Homo sapiens phosphorylase kinase, gamma 2 (testis) (PHKG2), mRNA. /FEA=mRNA /GEN=PHKG2 /PROD=phosphorylase kinase, gamma 2 (testis) /DB_XREF=gi:4505784 /UG=Hs.196177 phosphorylase kinase, gamma 2 (testis) /FL=gb:BC002541.1 gb:M31606.1 gb:NM_000294.1" NM_000294 "phosphorylase kinase, gamma 2 (testis)" PHKG2 5261 NM_000294 /// NM_001172432 /// XM_005255363 /// XM_005255364 /// XM_005255365 /// XM_006721054 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // traceable author statement /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045819 // positive regulation of glycogen catabolic process // traceable author statement 0005829 // cytosol // traceable author statement /// 0005964 // phosphorylase kinase complex // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004689 // phosphorylase kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // traceable author statement" 203710_at NM_002222 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002222.1 /DEF=Homo sapiens inositol 1,4,5-triphosphate receptor, type 1 (ITPR1), mRNA. /FEA=mRNA /GEN=ITPR1 /PROD=inositol 1,4,5-triphosphate receptor, type 1 /DB_XREF=gi:10835022 /UG=Hs.198443 inositol 1,4,5-triphosphate receptor, type 1 /FL=gb:NM_002222.1 gb:D26070.1" NM_002222 "inositol 1,4,5-trisphosphate receptor, type 1" ITPR1 3708 NM_001099952 /// NM_001168272 /// NM_002222 /// XM_005265109 /// XM_005265110 /// XM_006713131 /// XM_006713132 /// XM_006713133 /// XM_006713134 /// XM_006713135 /// XM_006713136 0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048016 // inositol phosphate-mediated signaling // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation 0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005955 // calcineurin complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation "0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity" 203711_s_at NM_014362 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014362.1 /DEF=Homo sapiens 3-hydroxyisobutyryl-Coenzyme A hydrolase (HIBCH), mRNA. /FEA=mRNA /GEN=HIBCH /PROD=3-hydroxyisobutyryl-Coenzyme A hydrolase /DB_XREF=gi:7657159 /UG=Hs.236642 3-hydroxyisobutyryl-Coenzyme A hydrolase /FL=gb:BC005190.1 gb:U66669.1 gb:NM_014362.1" NM_014362 3-hydroxyisobutyryl-CoA hydrolase HIBCH 26275 NM_014362 /// NM_198047 0006574 // valine catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0003860 // 3-hydroxyisobutyryl-CoA hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 203712_at NM_014878 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014878.1 /DEF=Homo sapiens KIAA0020 gene product (KIAA0020), mRNA. /FEA=mRNA /GEN=KIAA0020 /PROD=KIAA0020 gene product /DB_XREF=gi:7661865 /UG=Hs.2471 KIAA0020 gene product /FL=gb:D13645.1 gb:NM_014878.1" NM_014878 KIAA0020 KIAA0020 9933 NM_001031691 /// NM_014878 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203713_s_at NM_004524 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004524.1 /DEF=Homo sapiens lethal giant larvae (Drosophila) homolog 2 (LLGL2), mRNA. /FEA=mRNA /GEN=LLGL2 /PROD=lethal giant larvae (Drosophila) homolog 2 /DB_XREF=gi:4758679 /UG=Hs.3123 lethal giant larvae (Drosophila) homolog 2 /FL=gb:NM_004524.1" NM_004524 lethal giant larvae homolog 2 (Drosophila) LLGL2 3993 NM_001015002 /// NM_001031803 /// NM_004524 /// XM_006721897 /// XM_006721898 /// XM_006721899 /// XR_243659 0006887 // exocytosis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0032878 // regulation of establishment or maintenance of cell polarity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction 203714_s_at NM_003193 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003193.2 /DEF=Homo sapiens tubulin-specific chaperone e (TBCE), mRNA. /FEA=mRNA /GEN=TBCE /PROD=beta-tubulin cofactor E /DB_XREF=gi:6006029 /UG=Hs.32675 tubulin-specific chaperone e /FL=gb:U61232.1 gb:NM_003193.2" NM_003193 tubulin folding cofactor E TBCE 6905 NM_001079515 /// NM_001287801 /// NM_001287802 /// NM_003193 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0014889 // muscle atrophy // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048936 // peripheral nervous system neuron axonogenesis // inferred from electronic annotation /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 203715_at NM_003193 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003193.2 /DEF=Homo sapiens tubulin-specific chaperone e (TBCE), mRNA. /FEA=mRNA /GEN=TBCE /PROD=beta-tubulin cofactor E /DB_XREF=gi:6006029 /UG=Hs.32675 tubulin-specific chaperone e /FL=gb:U61232.1 gb:NM_003193.2" NM_003193 tubulin folding cofactor E TBCE 6905 NM_001079515 /// NM_001287801 /// NM_001287802 /// NM_003193 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007023 // post-chaperonin tubulin folding pathway // inferred from direct assay /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0014889 // muscle atrophy // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048589 // developmental growth // inferred from electronic annotation /// 0048936 // peripheral nervous system neuron axonogenesis // inferred from electronic annotation /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 203716_s_at M80536 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M80536.1 /DEF=H.sapiens dipeptidyl peptidase IV (DPP4) mRNA, complete cds. /FEA=mRNA /GEN=DPP4 /PROD=dipeptidyl peptidase IV /DB_XREF=gi:181569 /UG=Hs.44926 dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) /FL=gb:M80536.1 gb:NM_001935.1" M80536 dipeptidyl-peptidase 4 DPP4 1803 NM_001935 /// XM_005246371 0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203717_at NM_001935 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001935.1 /DEF=Homo sapiens dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) (DPP4), mRNA. /FEA=mRNA /GEN=DPP4 /PROD=dipeptidylpeptidase IV (CD26, adenosinedeaminase complexing protein 2) /DB_XREF=gi:4503366 /UG=Hs.44926 dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) /FL=gb:M80536.1 gb:NM_001935.1" NM_001935 dipeptidyl-peptidase 4 DPP4 1803 NM_001935 /// XM_005246371 0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203718_at NM_006702 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006702.1 /DEF=Homo sapiens neuropathy target esterase (NTE), mRNA. /FEA=mRNA /GEN=NTE /PROD=neuropathy target esterase /DB_XREF=gi:5729950 /UG=Hs.5038 neuropathy target esterase /FL=gb:NM_006702.1" NM_006702 patatin-like phospholipase domain containing 6 PNPLA6 10908 NM_001166111 /// NM_001166112 /// NM_001166113 /// NM_001166114 /// NM_006702 0001525 // angiogenesis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0046470 // phosphatidylcholine metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004622 // lysophospholipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203719_at NM_001983 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001983.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), mRNA. /FEA=mRNA /GEN=ERCC1 /PROD=excision repair cross-complementing rodentrepair deficiency, complementation group 1 (includesoverlapping antisense sequence) /DB_XREF=gi:4503598 /UG=Hs.59544 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) /FL=gb:M28650.1 gb:AF001925.1 gb:NM_001983.1 gb:M13194.1" NM_001983 excision repair cross-complementation group 1 ERCC1 2067 NM_001166049 /// NM_001983 /// NM_202001 /// XM_005258634 /// XM_005258635 /// XM_005258636 /// XM_005258637 "0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0001302 // replicative cell aging // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from genetic interaction /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from mutant phenotype /// 0006296 // nucleotide-excision repair, DNA incision, 5'-to lesion // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from genetic interaction /// 0006312 // mitotic recombination // inferred from mutant phenotype /// 0006949 // syncytium formation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0009650 // UV protection // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0032205 // negative regulation of telomere maintenance // inferred from mutant phenotype /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" "0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay" 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0001094 // TFIID-class transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043566 // structure-specific DNA binding // inferred from direct assay 203720_s_at NM_001983 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001983.1 /DEF=Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), mRNA. /FEA=mRNA /GEN=ERCC1 /PROD=excision repair cross-complementing rodentrepair deficiency, complementation group 1 (includesoverlapping antisense sequence) /DB_XREF=gi:4503598 /UG=Hs.59544 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) /FL=gb:M28650.1 gb:AF001925.1 gb:NM_001983.1 gb:M13194.1" NM_001983 excision repair cross-complementation group 1 ERCC1 2067 NM_001166049 /// NM_001983 /// NM_202001 /// XM_005258634 /// XM_005258635 /// XM_005258636 /// XM_005258637 "0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0000720 // pyrimidine dimer repair by nucleotide-excision repair // inferred from electronic annotation /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0001302 // replicative cell aging // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from direct assay /// 0006289 // nucleotide-excision repair // inferred from genetic interaction /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006295 // nucleotide-excision repair, DNA incision, 3'-to lesion // inferred from mutant phenotype /// 0006296 // nucleotide-excision repair, DNA incision, 5'-to lesion // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from genetic interaction /// 0006312 // mitotic recombination // inferred from mutant phenotype /// 0006949 // syncytium formation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0009650 // UV protection // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010259 // multicellular organismal aging // inferred from electronic annotation /// 0032205 // negative regulation of telomere maintenance // inferred from mutant phenotype /// 0035166 // post-embryonic hemopoiesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045190 // isotype switching // inferred from electronic annotation /// 0048468 // cell development // inferred from electronic annotation /// 0048477 // oogenesis // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" "0000109 // nucleotide-excision repair complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay" 0000014 // single-stranded DNA endodeoxyribonuclease activity // inferred from direct assay /// 0001094 // TFIID-class transcription factor binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043566 // structure-specific DNA binding // inferred from direct assay 203721_s_at NM_016001 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016001.1 /DEF=Homo sapiens CGI-48 protein (LOC51096), mRNA. /FEA=mRNA /GEN=LOC51096 /PROD=CGI-48 protein /DB_XREF=gi:7705764 /UG=Hs.6153 CGI-48 protein /FL=gb:AF151806.1 gb:NM_016001.1" NM_016001 UTP18 small subunit (SSU) processome component homolog (yeast) UTP18 51096 NM_016001 /// XM_006721930 0006364 // rRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203722_at NM_003748 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003748.1 /DEF=Homo sapiens aldehyde dehydrogenase 4 (glutamate gamma-semialdehyde dehydrogenase; pyrroline-5-carboxylate dehydrogenase) (ALDH4), mRNA. /FEA=mRNA /GEN=ALDH4 /PROD=aldehyde dehydrogenase 4 (glutamategamma-semialdehyde dehydrogenase; pyrroline-5-carboxylatedehydrogenase) /DB_XREF=gi:4502036 /UG=Hs.77448 aldehyde dehydrogenase 4 family, member A1 /FL=gb:U24266.1 gb:NM_003748.1" NM_003748 "aldehyde dehydrogenase 4 family, member A1" ALDH4A1 8659 NM_001161504 /// NM_003748 /// NM_170726 0006560 // proline metabolic process // traceable author statement /// 0006561 // proline biosynthetic process // inferred from electronic annotation /// 0006562 // proline catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010133 // proline catabolic process to glutamate // inferred from electronic annotation /// 0019470 // 4-hydroxyproline catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement "0003842 // 1-pyrroline-5-carboxylate dehydrogenase activity // not recorded /// 0004029 // aldehyde dehydrogenase (NAD) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction" 203723_at NM_002221 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002221.1 /DEF=Homo sapiens inositol 1,4,5-trisphosphate 3-kinase B (ITPKB), mRNA. /FEA=mRNA /GEN=ITPKB /PROD=1D-myo-inositol-trisphosphate 3-kinase B /DB_XREF=gi:4504790 /UG=Hs.78877 inositol 1,4,5-trisphosphate 3-kinase B /FL=gb:NM_002221.1" NM_002221 inositol-trisphosphate 3-kinase B ITPKB 3707 NM_002221 /// XM_005273120 0000165 // MAPK cascade // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045061 // thymic T cell selection // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008440 // inositol-1,4,5-trisphosphate 3-kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation" 203724_s_at NM_014961 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014961.1 /DEF=Homo sapiens KIAA0871 protein (KIAA0871), mRNA. /FEA=mRNA /GEN=KIAA0871 /PROD=KIAA0871 protein /DB_XREF=gi:7662351 /UG=Hs.7972 KIAA0871 protein /FL=gb:AB020678.1 gb:NM_014961.1" NM_014961 RUN and FYVE domain containing 3 RUFY3 22902 NM_001037442 /// NM_001130709 /// NM_001291993 /// NM_001291994 /// NM_014961 /// XM_005265656 /// XM_005265657 /// XM_005265658 /// XM_005265659 /// XM_006714148 /// XM_006714149 /// XM_006714150 /// XR_427534 /// XR_427535 /// XR_427536 /// XR_427537 /// XR_427538 /// XR_427539 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 203725_at NM_001924 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001924.2 /DEF=Homo sapiens growth arrest and DNA-damage-inducible, alpha (GADD45A), mRNA. /FEA=mRNA /GEN=GADD45A /PROD=growth arrest and DNA-damage-inducible, alpha /DB_XREF=gi:9790904 /UG=Hs.80409 growth arrest and DNA-damage-inducible, alpha /FL=gb:M60974.1 gb:NM_001924.2" NM_001924 "growth arrest and DNA-damage-inducible, alpha" GADD45A 1647 NM_001199741 /// NM_001199742 /// NM_001924 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007098 // centrosome cycle // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071479 // cellular response to ionizing radiation // inferred from mutant phenotype /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0001047 // core promoter binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203726_s_at NM_000227 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000227.1 /DEF=Homo sapiens laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin) (LAMA3), mRNA. /FEA=mRNA /GEN=LAMA3 /PROD=laminin alpha 3 subunit precursor /DB_XREF=gi:4557710 /UG=Hs.83450 laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin) /FL=gb:NM_000227.1 gb:L34155.1" NM_000227 "laminin, alpha 3" LAMA3 3909 NM_000227 /// NM_001127717 /// NM_001127718 /// NM_198129 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030155 // regulation of cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0045995 // regulation of embryonic development // inferred from electronic annotation" 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // traceable author statement /// 0005606 // laminin-1 complex // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 203727_at NM_006929 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006929.2 /DEF=Homo sapiens superkiller viralicidic activity 2 (S. cerevisiae homolog)-like (SKIV2L), mRNA. /FEA=mRNA /GEN=SKIV2L /PROD=superkiller viralicidic activity 2 (S.cerevisiae homolog)-like /DB_XREF=gi:13787218 /UG=Hs.89864 superkiller viralicidic activity 2 (S. cerevisiae homolog)-like /FL=gb:NM_006929.2 gb:U09877.1" NM_006929 superkiller viralicidic activity 2-like (S. cerevisiae) SKIV2L 6499 NM_006929 /// XM_006715168 /// XM_006725497 /// XR_430936 /// XR_430997 /// XR_431014 /// XR_431044 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0055087 // Ski complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation" 203728_at NM_001188 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001188.1 /DEF=Homo sapiens BCL2-antagonistkiller 1 (BAK1), mRNA. /FEA=mRNA /GEN=BAK1 /PROD=BCL2-antagonistkiller 1 /DB_XREF=gi:4502362 /UG=Hs.93213 BCL2-antagonistkiller 1 /FL=gb:BC004431.1 gb:NM_001188.1 gb:U16811.1 gb:U23765.1" NM_001188 BCL2-antagonist/killer 1 BAK1 578 NM_001188 /// XR_241910 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001783 // B cell apoptotic process // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0001836 // release of cytochrome c from mitochondria // inferred from genetic interaction /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0002352 // B cell negative selection // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008053 // mitochondrial fusion // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // inferred from electronic annotation /// 0009620 // response to fungus // inferred from electronic annotation /// 0010046 // response to mycotoxin // inferred from electronic annotation /// 0010225 // response to UV-C // inferred from electronic annotation /// 0010248 // establishment or maintenance of transmembrane electrochemical gradient // inferred from direct assay /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032471 // negative regulation of endoplasmic reticulum calcium ion concentration // inferred from electronic annotation /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from mutant phenotype /// 0034644 // cellular response to UV // inferred from sequence or structural similarity /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0044346 // fibroblast apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048597 // post-embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from direct assay /// 0060068 // vagina development // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from electronic annotation /// 0070242 // thymocyte apoptotic process // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // inferred from mutant phenotype /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // not recorded /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 0097202 // activation of cysteine-type endopeptidase activity // inferred from direct assay /// 1900103 // positive regulation of endoplasmic reticulum unfolded protein response // inferred from mutant phenotype /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902262 // apoptotic process involved in patterning of blood vessels // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031307 // integral component of mitochondrial outer membrane // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051087 // chaperone binding // inferred from electronic annotation /// 0051400 // BH domain binding // inferred from electronic annotation 203729_at NM_001425 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001425.1 /DEF=Homo sapiens epithelial membrane protein 3 (EMP3), mRNA. /FEA=mRNA /GEN=EMP3 /PROD=epithelial membrane protein 3 /DB_XREF=gi:4503562 /UG=Hs.9999 epithelial membrane protein 3 /FL=gb:U52101.1 gb:U87947.1 gb:NM_001425.1" NM_001425 epithelial membrane protein 3 EMP3 2014 NM_001425 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 203730_s_at BF196931 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF196931 /FEA=EST /DB_XREF=gi:11085491 /DB_XREF=est:7l80d06.x1 /CLONE=IMAGE:3527842 /UG=Hs.110839 zinc finger protein homologous to Zfp95 in mouse /FL=gb:NM_014569.1 gb:AB023232.1 BF196931 zinc finger with KRAB and SCAN domains 5 ZKSCAN5 23660 NM_014569 /// NM_145102 /// XM_005250242 /// XM_005250243 /// XM_006715912 /// XM_006715913 /// XM_006715914 /// XM_006715915 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203731_s_at NM_014569 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014569.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp95 in mouse (ZFP95), mRNA. /FEA=mRNA /GEN=ZFP95 /PROD=zinc finger protein homologous to Zfp95 inmouse /DB_XREF=gi:11036641 /UG=Hs.110839 zinc finger protein homologous to Zfp95 in mouse /FL=gb:NM_014569.1 gb:AB023232.1" NM_014569 zinc finger with KRAB and SCAN domains 5 ZKSCAN5 23660 NM_014569 /// NM_145102 /// XM_005250242 /// XM_005250243 /// XM_006715912 /// XM_006715913 /// XM_006715914 /// XM_006715915 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203732_at NM_016213 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016213.1 /DEF=Homo sapiens thyroid hormone receptor interactor 4 (TRIP4), mRNA. /FEA=mRNA /GEN=TRIP4 /PROD=activating signal cointegrator 1 /DB_XREF=gi:7706430 /UG=Hs.116784 thyroid hormone receptor interactor 4 /FL=gb:AF168418.1 gb:NM_016213.1" NM_016213 thyroid hormone receptor interactor 4 TRIP4 9325 NM_016213 /// XM_005254789 /// XR_243130 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203733_at NM_014015 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014015.2 /DEF=Homo sapiens MYLE protein (MYLE), mRNA. /FEA=mRNA /GEN=MYLE /PROD=MYLE protein /DB_XREF=gi:13384596 /UG=Hs.11902 MYLE protein /FL=gb:BC001083.1 gb:AF108145.2 gb:NM_014015.2" NM_014015 Dexi homolog (mouse) DEXI 28955 NM_014015 203734_at NM_018416 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018416.1 /DEF=Homo sapiens FOXJ2 forkhead factor (LOC55810), mRNA. /FEA=mRNA /GEN=LOC55810 /PROD=FOXJ2 forkhead factor /DB_XREF=gi:8923841 /UG=Hs.120844 FOXJ2 forkhead factor /FL=gb:AF155132.1 gb:NM_018416.1" NM_018416 forkhead box J2 FOXJ2 55810 NM_018416 /// XM_005253430 /// XM_005253431 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay "0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from direct assay" 203735_x_at N35896 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N35896 /FEA=EST /DB_XREF=gi:1157038 /DB_XREF=est:yy28c08.s1 /CLONE=IMAGE:272558 /UG=Hs.133207 PTPRF interacting protein, binding protein 1 (liprin beta 1) /FL=gb:AF034802.1 gb:NM_003622.1" N35896 "PTPRF interacting protein, binding protein 1 (liprin beta 1)" PPFIBP1 8496 NM_001198915 /// NM_001198916 /// NM_003622 /// NM_177444 /// XM_005253505 /// XM_005253506 /// XM_005253507 /// XM_005253508 /// XM_005253509 /// XM_005253510 /// XM_005253511 /// XM_005253514 /// XM_005253515 /// XM_005253516 /// XM_006719159 /// XM_006719160 /// XM_006719161 0007155 // cell adhesion // traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008907 // integrase activity // inferred from electronic annotation 203736_s_at NM_003622 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003622.1 /DEF=Homo sapiens PTPRF interacting protein, binding protein 1 (liprin beta 1) (PPFIBP1), mRNA. /FEA=mRNA /GEN=PPFIBP1 /PROD=PTPRF interacting protein, binding protein 1(liprin beta 1) /DB_XREF=gi:4505986 /UG=Hs.133207 PTPRF interacting protein, binding protein 1 (liprin beta 1) /FL=gb:AF034802.1 gb:NM_003622.1" NM_003622 "PTPRF interacting protein, binding protein 1 (liprin beta 1)" PPFIBP1 8496 NM_001198915 /// NM_001198916 /// NM_003622 /// NM_177444 /// XM_005253505 /// XM_005253506 /// XM_005253507 /// XM_005253508 /// XM_005253509 /// XM_005253510 /// XM_005253511 /// XM_005253514 /// XM_005253515 /// XM_005253516 /// XM_006719159 /// XM_006719160 /// XM_006719161 0007155 // cell adhesion // traceable author statement /// 0015074 // DNA integration // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008907 // integrase activity // inferred from electronic annotation 203737_s_at NM_015062 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015062.1 /DEF=Homo sapiens KIAA0595 protein (KIAA0595), mRNA. /FEA=mRNA /GEN=KIAA0595 /PROD=KIAA0595 protein /DB_XREF=gi:13124753 /UG=Hs.146957 KIAA0595 protein /FL=gb:BC002561.1 gb:AF325193.1 gb:NM_015062.1" NM_015062 "peroxisome proliferator-activated receptor gamma, coactivator-related 1" PPRC1 23082 NM_001288727 /// NM_001288728 /// NM_015062 /// XM_005269656 /// XM_005269658 /// XM_006717730 /// XM_006717731 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203738_at AI421192 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI421192 /FEA=EST /DB_XREF=gi:4267123 /DB_XREF=est:tf24e12.x1 /CLONE=IMAGE:2097166 /UG=Hs.151046 hypothetical protein FLJ11193 /FL=gb:NM_018356.1 AI421192 chromosome 5 open reading frame 22 C5orf22 55322 NM_018356 /// XM_005248319 /// XM_006714479 /// XM_006714480 /// XR_241704 0008013 // beta-catenin binding // inferred from electronic annotation 203739_at NM_006526 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006526.1 /DEF=Homo sapiens zinc finger protein 217 (ZNF217), mRNA. /FEA=mRNA /GEN=ZNF217 /PROD=zinc finger protein 217 /DB_XREF=gi:5730123 /UG=Hs.155040 zinc finger protein 217 /FL=gb:AF041259.1 gb:NM_006526.1" NM_006526 zinc finger protein 217 ZNF217 7764 NM_006526 /// XM_005260545 /// XM_006723875 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay" 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203740_at NM_005792 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005792.1 /DEF=Homo sapiens M-phase phosphoprotein 6 (MPHOSPH6), mRNA. /FEA=mRNA /GEN=MPHOSPH6 /PROD=M-phase phosphoprotein 6 /DB_XREF=gi:5031918 /UG=Hs.152720 M-phase phosphoprotein 6 /FL=gb:BC005242.1 gb:NM_005792.1" NM_005792 M-phase phosphoprotein 6 MPHOSPH6 10200 NM_005792 0000087 // mitotic M phase // traceable author statement /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from electronic annotation 0000176 // nuclear exosome (RNase complex) // traceable author statement /// 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203741_s_at NM_001114 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001114.1 /DEF=Homo sapiens adenylate cyclase 7 (ADCY7), mRNA. /FEA=mRNA /GEN=ADCY7 /PROD=adenylate cyclase 7 /DB_XREF=gi:4557254 /UG=Hs.172199 adenylate cyclase 7 /FL=gb:D25538.1 gb:NM_001114.1" NM_001114 adenylate cyclase 7 ADCY7 113 NM_001114 /// NM_001286057 /// XM_005255779 /// XM_005255780 /// XM_005255781 /// XM_005255782 /// XM_005255783 /// XM_005255784 /// XM_005255785 /// XM_005255786 /// XM_006721128 "0006112 // energy reserve metabolic process // traceable author statement /// 0006171 // cAMP biosynthetic process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006833 // water transport // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007189 // adenylate cyclase-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from direct assay /// 0034199 // activation of protein kinase A activity // traceable author statement /// 0035066 // positive regulation of histone acetylation // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0071361 // cellular response to ethanol // inferred from direct assay /// 0071377 // cellular response to glucagon stimulus // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from sequence or structural similarity /// 0004016 // adenylate cyclase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 203742_s_at BF674842 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF674842 /FEA=EST /DB_XREF=gi:11948737 /DB_XREF=est:602136708F1 /CLONE=IMAGE:4273393 /UG=Hs.173824 thymine-DNA glycosylase /FL=gb:U51166.1 gb:NM_003211.1 BF674842 G/T mismatch-specific thymine DNA glycosylase-like /// thymine-DNA glycosylase LOC732360 /// TDG 6996 /// 732360 NM_001008411 /// NM_003211 /// XM_005269125 /// XR_133016 /// XR_429113 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from sequence or structural similarity /// 0045008 // depyrimidination // traceable author statement /// 0080111 // DNA demethylation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation "0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032183 // SUMO binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043566 // structure-specific DNA binding // inferred from sequence or structural similarity" 203743_s_at NM_003211 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003211.1 /DEF=Homo sapiens thymine-DNA glycosylase (TDG), mRNA. /FEA=mRNA /GEN=TDG /PROD=thymine-DNA glycosylase /DB_XREF=gi:4507422 /UG=Hs.173824 thymine-DNA glycosylase /FL=gb:U51166.1 gb:NM_003211.1" NM_003211 thymine-DNA glycosylase TDG 6996 NM_001008411 /// NM_003211 /// XM_005269125 /// XR_429113 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // inferred from direct assay /// 0006284 // base-excision repair // traceable author statement /// 0006285 // base-excision repair, AP site formation // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0035562 // negative regulation of chromatin binding // inferred from electronic annotation /// 0040029 // regulation of gene expression, epigenetic // inferred from sequence or structural similarity /// 0045008 // depyrimidination // traceable author statement /// 0080111 // DNA demethylation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation "0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003684 // damaged DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008263 // pyrimidine-specific mismatch base pair DNA N-glycosylase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0019104 // DNA N-glycosylase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032183 // SUMO binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043566 // structure-specific DNA binding // inferred from sequence or structural similarity" 203744_at NM_005342 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005342.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 4 (HMG4), mRNA. /FEA=mRNA /GEN=HMG4 /PROD=high-mobility group (nonhistone chromosomal)protein 4 /DB_XREF=gi:4885420 /UG=Hs.19114 high-mobility group (nonhistone chromosomal) protein 4 /FL=gb:NM_005342.1" NM_005342 high mobility group box 3 HMGB3 3149 NM_005342 /// XM_005274665 /// XM_005274666 /// XM_005274667 0006310 // DNA recombination // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation "0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from sequence or structural similarity /// 0008301 // DNA binding, bending // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay" 203745_at AI801013 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI801013 /FEA=EST /DB_XREF=gi:5366485 /DB_XREF=est:wg15d09.x1 /CLONE=IMAGE:2365169 /UG=Hs.211571 holocytochrome c synthase (cytochrome c heme-lyase) /FL=gb:U36787.1 gb:NM_005333.1 AI801013 holocytochrome c synthase HCCS 3052 NM_001122608 /// NM_001171991 /// NM_005333 0008152 // metabolic process // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004408 // holocytochrome-c synthase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203746_s_at NM_005333 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005333.1 /DEF=Homo sapiens holocytochrome c synthase (cytochrome c heme-lyase) (HCCS), mRNA. /FEA=mRNA /GEN=HCCS /PROD=holocytochrome c synthase (cytochrome cheme-lyase) /DB_XREF=gi:4885400 /UG=Hs.211571 holocytochrome c synthase (cytochrome c heme-lyase) /FL=gb:U36787.1 gb:NM_005333.1" NM_005333 holocytochrome c synthase HCCS 3052 NM_001122608 /// NM_001171991 /// NM_005333 0008152 // metabolic process // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004408 // holocytochrome-c synthase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203747_at NM_004925 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004925.2 /DEF=Homo sapiens aquaporin 3 (AQP3), mRNA. /FEA=mRNA /GEN=AQP3 /PROD=aquaporin 3 /DB_XREF=gi:9257193 /UG=Hs.234642 aquaporin 3 /FL=gb:NM_004925.2" NM_004925 aquaporin 3 (Gill blood group) AQP3 360 NM_004925 0002684 // positive regulation of immune system process // inferred from direct assay /// 0006810 // transport // non-traceable author statement /// 0006833 // water transport // traceable author statement /// 0007588 // excretion // traceable author statement /// 0015793 // glycerol transport // inferred from electronic annotation /// 0015840 // urea transport // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0033280 // response to vitamin D // traceable author statement /// 0042476 // odontogenesis // inferred from expression pattern /// 0045616 // regulation of keratinocyte differentiation // traceable author statement /// 0051592 // response to calcium ion // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015250 // water channel activity // not recorded /// 0015250 // water channel activity // traceable author statement /// 0015254 // glycerol channel activity // inferred from direct assay 203748_x_at NM_016839 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016839.1 /DEF=Homo sapiens RNA binding motif, single stranded interacting protein 1 (RBMS1), transcript variant MSSP-2, mRNA. /FEA=mRNA /GEN=RBMS1 /PROD=RNA binding motif, single stranded interactingprotein 1, isoform b /DB_XREF=gi:8400723 /UG=Hs.241567 RNA binding motif, single stranded interacting protein 1 /FL=gb:NM_016839.1" NM_016839 "RNA binding motif, single stranded interacting protein 1" RBMS1 5937 NM_002897 /// NM_016836 /// NM_016839 /// XM_005246737 /// XM_005246738 /// XM_005246739 /// XM_005246740 /// XM_005246741 /// XM_006712671 /// XM_006712672 /// XM_006712673 /// XM_006712674 /// XM_006712675 0006260 // DNA replication // non-traceable author statement /// 0006396 // RNA processing // traceable author statement 0005634 // nucleus // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // non-traceable author statement /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203749_s_at AI806984 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI806984 /FEA=EST /DB_XREF=gi:5393550 /DB_XREF=est:wf24g08.x1 /CLONE=IMAGE:2356574 /UG=Hs.250505 retinoic acid receptor, alpha /FL=gb:NM_000964.1" AI806984 "retinoic acid receptor, alpha" RARA 5914 NM_000964 /// NM_001024809 /// NM_001033603 /// NM_001145301 /// NM_001145302 /// XM_005257552 /// XM_005257553 /// XM_005257554 /// XM_005257555 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0000790 // nuclear chromatin // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred by curator /// 0030425 // dendrite // inferred from electronic annotation /// 0031264 // death-inducing signaling complex // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay" 203750_s_at NM_000964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000964.1 /DEF=Homo sapiens retinoic acid receptor, alpha (RARA), mRNA. /FEA=mRNA /GEN=RARA /PROD=retinoic acid receptor, alpha /DB_XREF=gi:4506418 /UG=Hs.250505 retinoic acid receptor, alpha /FL=gb:NM_000964.1" NM_000964 "retinoic acid receptor, alpha" RARA 5914 NM_000964 /// NM_001024809 /// NM_001033603 /// NM_001145301 /// NM_001145302 /// XM_005257552 /// XM_005257553 /// XM_005257554 /// XM_005257555 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0030520 // intracellular estrogen receptor signaling pathway // inferred from direct assay /// 0030850 // prostate gland development // inferred from electronic annotation /// 0030852 // regulation of granulocyte differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from mutant phenotype /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032736 // positive regulation of interleukin-13 production // inferred from direct assay /// 0032753 // positive regulation of interleukin-4 production // inferred from direct assay /// 0032754 // positive regulation of interleukin-5 production // inferred from direct assay /// 0033189 // response to vitamin A // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0043551 // regulation of phosphatidylinositol 3-kinase activity // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045630 // positive regulation of T-helper 2 cell differentiation // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045787 // positive regulation of cell cycle // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045947 // negative regulation of translational initiation // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from mutant phenotype /// 0051099 // positive regulation of binding // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055012 // ventricular cardiac muscle cell differentiation // inferred from electronic annotation /// 0060010 // Sertoli cell fate commitment // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from direct assay /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred by curator /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0001972 // retinoic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from direct assay /// 0035014 // phosphatidylinositol 3-kinase regulator activity // inferred from electronic annotation /// 0043422 // protein kinase B binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0044323 // retinoic acid-responsive element binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0048027 // mRNA 5'-UTR binding // inferred from electronic annotation /// 0051018 // protein kinase A binding // inferred from direct assay" 203751_x_at AI762296 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI762296 /FEA=EST /DB_XREF=gi:5177963 /DB_XREF=est:wh86e06.x1 /CLONE=IMAGE:2387650 /UG=Hs.2780 jun D proto-oncogene /FL=gb:NM_005354.2 AI762296 jun D proto-oncogene JUND 3727 NM_001286968 /// NM_005354 "0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation" 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203752_s_at NM_005354 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005354.2 /DEF=Homo sapiens jun D proto-oncogene (JUND), mRNA. /FEA=mRNA /GEN=JUND /PROD=jun D proto-oncogene /DB_XREF=gi:10938013 /UG=Hs.2780 jun D proto-oncogene /FL=gb:NM_005354.2" NM_005354 jun D proto-oncogene JUND 3727 NM_001286968 /// NM_005354 "0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation" 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay 203753_at NM_003199 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003199.1 /DEF=Homo sapiens transcription factor 4 (TCF4), mRNA. /FEA=mRNA /GEN=TCF4 /PROD=transcription factor 4, isoform b /DB_XREF=gi:4507398 /UG=Hs.326198 transcription factor 4 /FL=gb:M74719.1 gb:NM_003199.1" NM_003199 transcription factor 4 TCF4 6925 NM_001083962 /// NM_001243226 /// NM_001243227 /// NM_001243228 /// NM_001243230 /// NM_001243231 /// NM_001243232 /// NM_001243233 /// NM_001243234 /// NM_001243235 /// NM_001243236 /// NM_003199 /// XM_005266739 /// XM_005266741 /// XM_005266743 /// XM_005266744 /// XM_005266745 /// XM_005266746 /// XM_005266747 /// XM_005266749 /// XM_005266750 /// XM_005266752 /// XM_005266754 /// XM_005266755 /// XM_005266761 /// XM_006722529 /// XM_006722530 /// XM_006722531 /// XM_006722532 /// XM_006722533 /// XM_006722534 /// XM_006722535 /// XM_006722536 /// XM_006722537 /// XM_006722538 /// XM_006722539 /// XM_006722540 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0065004 // protein-DNA complex assembly // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001011 // sequence-specific DNA binding RNA polymerase recruiting transcription factor activity // inferred from sequence or structural similarity /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from sequence or structural similarity /// 0001087 // TFIIB-class binding transcription factor activity // inferred from sequence or structural similarity /// 0001093 // TFIIB-class transcription factor binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // non-traceable author statement /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0070888 // E-box binding // inferred from sequence or structural similarity 203754_s_at NM_001519 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001519.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2 (TAF3B2), mRNA. /FEA=mRNA /GEN=TAF3B2 /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase III, GTF3B subunit 2 /DB_XREF=gi:4507354 /UG=Hs.32935 TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2 /FL=gb:U75276.1 gb:NM_001519.1 gb:U28838.1" NM_001519 "BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit" BRF1 2972 NM_001242786 /// NM_001242787 /// NM_001242788 /// NM_001242789 /// NM_001242790 /// NM_001519 /// NM_145685 /// NM_145696 /// XM_005267561 /// XM_005267563 /// XM_006720122 /// XM_006720123 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0006384 // transcription initiation from RNA polymerase III promoter // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation /// 0009303 // rRNA transcription // traceable author statement /// 0009304 // tRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation" 0000126 // transcription factor TFIIIB complex // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203755_at NM_001211 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001211.2 /DEF=Homo sapiens budding uninhibited by benzimidazoles 1 (yeast homolog), beta (BUB1B), mRNA. /FEA=mRNA /GEN=BUB1B /PROD=budding uninhibited by benzimidazoles 1 (yeasthomolog), beta /DB_XREF=gi:5729749 /UG=Hs.36708 budding uninhibited by benzimidazoles 1 (yeast homolog), beta /FL=gb:AF053306.1 gb:AF035933.1 gb:AF068760.1 gb:AF046918.1 gb:AF107297.1 gb:AF046079.2 gb:NM_001211.2" NM_001211 BUB1 mitotic checkpoint serine/threonine kinase B BUB1B 701 NM_001211 "0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from physical interaction /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0071459 // protein localization to chromosome, centromeric region // inferred from electronic annotation" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000776 // kinetochore // non-traceable author statement /// 0000776 // kinetochore // traceable author statement /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000778 // condensed nuclear chromosome kinetochore // inferred from electronic annotation /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005680 // anaphase-promoting complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // non-traceable author statement" "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203756_at NM_014786 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014786.1 /DEF=Homo sapiens KIAA0337 gene product (KIAA0337), mRNA. /FEA=mRNA /GEN=KIAA0337 /PROD=KIAA0337 gene product /DB_XREF=gi:7662063 /UG=Hs.45180 KIAA0337 gene product /FL=gb:AB002335.1 gb:NM_014786.1" NM_014786 Rho guanine nucleotide exchange factor (GEF) 17 ARHGEF17 9828 NM_014786 /// XM_006718752 0007155 // cell adhesion // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203757_s_at BC005008 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005008.1 /DEF=Homo sapiens, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen), clone MGC:10467, mRNA, complete cds. /FEA=mRNA /PROD=carcinoembryonic antigen-related cell adhesionmolecule 6 (non-specific cross reacting antigen) /DB_XREF=gi:13477106 /UG=Hs.73848 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) /FL=gb:BC005008.1 gb:M18216.1 gb:M29541.1 gb:NM_002483.1" BC005008 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) CEACAM6 4680 NM_002483 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203758_at AV729484 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV729484 /FEA=EST /DB_XREF=gi:10838905 /DB_XREF=est:AV729484 /CLONE=HTCAVA12 /UG=Hs.75262 cathepsin O /FL=gb:NM_001334.1 AV729484 cathepsin O CTSO 1519 NM_001334 0006508 // proteolysis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203759_at NM_006278 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006278.1 /DEF=Homo sapiens sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) (SIAT4C), mRNA. /FEA=mRNA /GEN=SIAT4C /PROD=sialyltransferase 4C (beta-galactosidasealpha-2,3-sialytransferase) /DB_XREF=gi:5454057 /UG=Hs.75268 sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) /FL=gb:L23767.1 gb:NM_006278.1" NM_006278 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" ST3GAL4 6484 NM_001254757 /// NM_001254758 /// NM_001254759 /// NM_006278 /// XM_005271649 /// XM_005271650 /// XM_005271651 /// XM_006718896 /// XM_006718897 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003836 // beta-galactoside (CMP) alpha-2,3-sialyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0047288 // monosialoganglioside sialyltransferase activity // inferred from electronic annotation" 203760_s_at U44403 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U44403.1 /DEF=Human Src-like adapter protein mRNA, complete cds. /FEA=mRNA /PROD=Src-like adapter protein /DB_XREF=gi:1809245 /UG=Hs.75367 Src-like-adapter /FL=gb:U30473.1 gb:D89077.1 gb:U44403.1 gb:NM_006748.1" U44403 Src-like-adaptor SLA 6503 NM_001045556 /// NM_001045557 /// NM_001282964 /// NM_001282965 /// NM_006748 0009967 // positive regulation of signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203761_at NM_006748 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006748.1 /DEF=Homo sapiens Src-like-adapter (SLA), mRNA. /FEA=mRNA /GEN=SLA /PROD=Src-like-adapter /DB_XREF=gi:5803170 /UG=Hs.75367 Src-like-adapter /FL=gb:U30473.1 gb:D89077.1 gb:U44403.1 gb:NM_006748.1" NM_006748 Src-like-adaptor SLA 6503 NM_001045556 /// NM_001045557 /// NM_001282964 /// NM_001282965 /// NM_006748 0009967 // positive regulation of signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203762_s_at NM_016008 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016008.1 /DEF=Homo sapiens CGI-60 protein (LOC51626), mRNA. /FEA=mRNA /GEN=LOC51626 /PROD=CGI-60 protein /DB_XREF=gi:7706299 /UG=Hs.7627 CGI-60 protein /FL=gb:AF151818.1 gb:NM_016008.1" NM_016008 "dynein, cytoplasmic 2, light intermediate chain 1" DYNC2LI1 51626 NM_001012665 /// NM_001193464 /// NM_015522 /// NM_016008 /// XM_005264364 /// XM_005264365 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0030286 // dynein complex // inferred from electronic annotation /// 0030990 // intraciliary transport particle // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from sequence or structural similarity /// 0072372 // primary cilium // inferred from sequence or structural similarity 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203763_at NM_016008 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016008.1 /DEF=Homo sapiens CGI-60 protein (LOC51626), mRNA. /FEA=mRNA /GEN=LOC51626 /PROD=CGI-60 protein /DB_XREF=gi:7706299 /UG=Hs.7627 CGI-60 protein /FL=gb:AF151818.1 gb:NM_016008.1" NM_016008 "dynein, cytoplasmic 2, light intermediate chain 1" DYNC2LI1 51626 NM_001012665 /// NM_001193464 /// NM_015522 /// NM_016008 /// XM_005264364 /// XM_005264365 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from sequence or structural similarity /// 0005929 // cilium // inferred from electronic annotation /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0030286 // dynein complex // inferred from electronic annotation /// 0030990 // intraciliary transport particle // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0036064 // ciliary basal body // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from sequence or structural similarity /// 0072372 // primary cilium // inferred from sequence or structural similarity 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203764_at NM_014750 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014750.1 /DEF=Homo sapiens KIAA0008 gene product (KIAA0008), mRNA. /FEA=mRNA /GEN=KIAA0008 /PROD=KIAA0008 gene product /DB_XREF=gi:7661851 /UG=Hs.77695 KIAA0008 gene product /FL=gb:D13633.1 gb:NM_014750.1" NM_014750 "discs, large (Drosophila) homolog-associated protein 5" DLGAP5 9787 NM_001146015 /// NM_014750 0000087 // mitotic M phase // inferred from direct assay /// 0000087 // mitotic M phase // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007079 // mitotic chromosome movement towards spindle pole // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008283 // cell proliferation // non-traceable author statement /// 0016311 // dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from sequence or structural similarity /// 0045842 // positive regulation of mitotic metaphase/anaphase transition // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from sequence or structural similarity 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 203765_at NM_012198 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012198.1 /DEF=Homo sapiens grancalcin (GCL), mRNA. /FEA=mRNA /GEN=GCL /PROD=grancalcin /DB_XREF=gi:6912387 /UG=Hs.79381 grancalcin /FL=gb:BC005214.1 gb:M81637.1 gb:NM_012198.1" NM_012198 "grancalcin, EF-hand calcium binding protein" GCA 25801 NM_012198 /// XM_005246446 /// XM_006712398 /// XM_006712399 /// XM_006712400 /// XM_006712401 0006508 // proteolysis // not recorded /// 0061025 // membrane fusion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0005509 // calcium ion binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 203766_s_at NM_012134 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012134.1 /DEF=Homo sapiens leiomodin 1 (smooth muscle) (LMOD1), mRNA. /FEA=mRNA /GEN=LMOD1 /PROD=leiomodin 1 (smooth muscle) /DB_XREF=gi:6912323 /UG=Hs.79386 leiomodin 1 (smooth muscle) /FL=gb:NM_012134.1" NM_012134 leiomodin 1 (smooth muscle) LMOD1 25802 NM_012134 0006936 // muscle contraction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation 203767_s_at AI122754 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI122754 /FEA=EST /DB_XREF=gi:3538520 /DB_XREF=est:qa48e01.x1 /CLONE=IMAGE:1690008 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1" AI122754 "steroid sulfatase (microsomal), isozyme S" STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203768_s_at AU138166 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU138166 /FEA=EST /DB_XREF=gi:10999687 /DB_XREF=est:AU138166 /CLONE=PLACE1007987 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1" AU138166 "steroid sulfatase (microsomal), isozyme S" STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203769_s_at NM_000351 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000351.2 /DEF=Homo sapiens steroid sulfatase (microsomal), arylsulfatase C, isozyme S (STS), mRNA. /FEA=mRNA /GEN=STS /PROD=steroid sulfatase (microsomal), arylsulfatase C,isozyme S /DB_XREF=gi:13162281 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1" NM_000351 "steroid sulfatase (microsomal), isozyme S" STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203770_s_at J04964 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J04964.1 /DEF=Human steroid sulfatase (microsomal), complete cds. /FEA=mRNA /GEN=STS /DB_XREF=gi:338564 /UG=Hs.79876 steroid sulfatase (microsomal), arylsulfatase C, isozyme S /FL=gb:NM_000351.2 gb:M16505.1 gb:J04964.1" J04964 "steroid sulfatase (microsomal), isozyme S" STS 412 NM_000351 /// XM_005274511 /// XM_006724488 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006706 // steroid catabolic process // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // traceable author statement /// 0005768 // endosome // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004773 // steryl-sulfatase activity // traceable author statement /// 0008484 // sulfuric ester hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203771_s_at AA740186 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA740186 /FEA=EST /DB_XREF=gi:2778778 /DB_XREF=est:ob26e06.s1 /CLONE=IMAGE:1324834 /UG=Hs.81029 biliverdin reductase A /FL=gb:U34877.1 gb:NM_000712.1 AA740186 biliverdin reductase A BLVRA 644 NM_000712 /// NM_001253823 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004074 // biliverdin reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203772_at U34877 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:U34877.1 /DEF=Homo sapiens biliverdin-IX alpha reductase mRNA, complete cds. /FEA=mRNA /PROD=biliverdin-IX alpha reductase /DB_XREF=gi:1143231 /UG=Hs.81029 biliverdin reductase A /FL=gb:U34877.1 gb:NM_000712.1" U34877 biliverdin reductase A BLVRA 644 NM_000712 /// NM_001253823 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004074 // biliverdin reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203773_x_at NM_000712 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000712.1 /DEF=Homo sapiens biliverdin reductase A (BLVRA), mRNA. /FEA=mRNA /GEN=BLVRA /PROD=biliverdin reductase A /DB_XREF=gi:4502416 /UG=Hs.81029 biliverdin reductase A /FL=gb:U34877.1 gb:NM_000712.1" NM_000712 biliverdin reductase A BLVRA 644 NM_000712 /// NM_001253823 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0042167 // heme catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004074 // biliverdin reductase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203774_at NM_000254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000254.1 /DEF=Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), mRNA. /FEA=mRNA /GEN=MTR /PROD=5-methyltetrahydrofolate-homocysteinemethyltransferase /DB_XREF=gi:4557764 /UG=Hs.82283 5-methyltetrahydrofolate-homocysteine methyltransferase /FL=gb:U73338.1 gb:U75743.1 gb:U71285.1 gb:NM_000254.1" NM_000254 5-methyltetrahydrofolate-homocysteine methyltransferase MTR 4548 NM_000254 /// NM_001291939 /// NM_001291940 /// XM_005273141 /// XM_005273143 /// XM_005273145 /// XM_006711769 /// XM_006711770 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009086 // methionine biosynthetic process // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0032259 // methylation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042558 // pteridine-containing compound metabolic process // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008705 // methionine synthase activity // inferred from electronic annotation /// 0008898 // S-adenosylmethionine-homocysteine S-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0031419 // cobalamin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203775_at NM_014251 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014251.1 /DEF=Homo sapiens solute carrier family 25, member 13 (citrin) (SLC25A13), mRNA. /FEA=mRNA /GEN=SLC25A13 /PROD=solute carrier family 25, member 13 (citrin) /DB_XREF=gi:7657580 /UG=Hs.9599 solute carrier family 25, member 13 (citrin) /FL=gb:AF118838.1 gb:NM_014251.1" NM_014251 "solute carrier family 25 (aspartate/glutamate carrier), member 13" SLC25A13 10165 NM_001160210 /// NM_014251 /// NR_027662 /// XM_006715830 /// XM_006715831 /// XM_006715832 /// XM_006715833 /// XM_006715834 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006754 // ATP biosynthetic process // inferred from direct assay /// 0006810 // transport // non-traceable author statement /// 0015810 // aspartate transport // inferred from direct assay /// 0015813 // L-glutamate transport // inferred from direct assay /// 0043490 // malate-aspartate shuttle // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0015183 // L-aspartate transmembrane transporter activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203776_at NM_015698 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015698.1 /DEF=Homo sapiens T54 protein (T54), mRNA. /FEA=mRNA /GEN=T54 /PROD=T54 protein /DB_XREF=gi:7662668 /UG=Hs.100391 T54 protein /FL=gb:BC000397.1 gb:BC003148.1 gb:U66359.1 gb:NM_015698.1" NM_015698 G patch domain and KOW motifs GPKOW 27238 NM_015698 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203777_s_at NM_003952 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003952.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 70kD, polypeptide 2 (RPS6KB2), mRNA. /FEA=mRNA /GEN=RPS6KB2 /PROD=p70 ribosomal S6 kinase beta /DB_XREF=gi:4506738 /UG=Hs.103081 ribosomal protein S6 kinase, 70kD, polypeptide 2 /FL=gb:BC000094.1 gb:AB016869.1 gb:AB019245.1 gb:AF099739.1 gb:NM_003952.1 gb:AF076931.1" NM_003952 "ribosomal protein S6 kinase, 70kDa, polypeptide 2" RPS6KB2 6199 NM_001007071 /// NM_003952 /// XM_005274164 /// XM_005274165 /// XM_006718655 /// XM_006718656 /// XM_006718657 /// XR_247207 /// XR_247208 0006412 // translation // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004711 // ribosomal protein S6 kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation" 203778_at NM_005908 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005908.1 /DEF=Homo sapiens mannosidase, beta A, lysosomal (MANBA), mRNA. /FEA=mRNA /GEN=MANBA /PROD=mannosidase, beta A, lysosomal /DB_XREF=gi:5174522 /UG=Hs.115945 mannosidase, beta A, lysosomal /FL=gb:U60337.1 gb:NM_005908.1" NM_005908 "mannosidase, beta A, lysosomal" MANBA 4126 NM_005908 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006464 // cellular protein modification process // non-traceable author statement /// 0006516 // glycoprotein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0046355 // mannan catabolic process // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay "0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004567 // beta-mannosidase activity // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation" 203779_s_at NM_005797 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005797.1 /DEF=Homo sapiens epithelial V-like antigen 1 (EVA1), mRNA. /FEA=mRNA /GEN=EVA1 /PROD=epithelial V-like antigen 1 precursor /DB_XREF=gi:5032246 /UG=Hs.116651 epithelial V-like antigen 1 /FL=gb:AF304447.1 gb:AF030455.1 gb:NM_005797.1 gb:AF275945.1" NM_005797 myelin protein zero-like 2 MPZL2 10205 NM_005797 /// NM_144765 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203780_at AF275945 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF275945.1 /DEF=Homo sapiens epithelial V-like antigen 1 (EVA1) mRNA, complete cds. /FEA=mRNA /GEN=EVA1 /PROD=epithelial V-like antigen 1 /DB_XREF=gi:9392652 /UG=Hs.116651 epithelial V-like antigen 1 /FL=gb:AF304447.1 gb:AF030455.1 gb:NM_005797.1 gb:AF275945.1" AF275945 myelin protein zero-like 2 MPZL2 10205 NM_005797 /// NM_144765 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203781_at NM_004891 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004891.1 /DEF=Homo sapiens chromosome 2 open reading frame 1 (C2ORF1), mRNA. /FEA=mRNA /GEN=C2ORF1 /PROD=chromosome 2 open reading frame 1 /DB_XREF=gi:4759047 /UG=Hs.14454 chromosome 2 open reading frame 1 /FL=gb:AF047440.1 gb:NM_004891.1" NM_004891 mitochondrial ribosomal protein L33 MRPL33 9553 NM_004891 /// NM_145330 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 203782_s_at NM_005035 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005035.1 /DEF=Homo sapiens polymerase (RNA) mitochondrial (DNA directed) (POLRMT), mRNA. /FEA=mRNA /GEN=POLRMT /PROD=polymerase (RNA) mitochondrial (DNA directed) /DB_XREF=gi:4826925 /UG=Hs.153880 polymerase (RNA) mitochondrial (DNA directed) /FL=gb:U75370.1 gb:NM_005035.1" NM_005035 polymerase (RNA) mitochondrial (DNA directed) POLRMT 5442 NM_005035 /// XM_005259580 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from direct assay /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203783_x_at BF057617 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF057617 /FEA=EST /DB_XREF=gi:10811513 /DB_XREF=est:7k46g11.x1 /CLONE=IMAGE:3478485 /UG=Hs.153880 polymerase (RNA) mitochondrial (DNA directed) /FL=gb:U75370.1 gb:NM_005035.1 BF057617 polymerase (RNA) mitochondrial (DNA directed) POLRMT 5442 NM_005035 /// XM_005259580 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from direct assay /// 0006390 // transcription from mitochondrial promoter // traceable author statement /// 0006391 // transcription initiation from mitochondrial promoter // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0003899 // DNA-directed RNA polymerase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203784_s_at BG477502 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG477502 /FEA=EST /DB_XREF=gi:13409781 /DB_XREF=est:602521562F1 /CLONE=IMAGE:4640031 /UG=Hs.155049 hypothetical protein FLJ11282 /FL=gb:NM_018380.1 BG477502 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 DDX28 55794 NM_018380 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203785_s_at NM_018380 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018380.1 /DEF=Homo sapiens hypothetical protein FLJ11282 (FLJ11282), mRNA. /FEA=mRNA /GEN=FLJ11282 /PROD=hypothetical protein FLJ11282 /DB_XREF=gi:8922975 /UG=Hs.155049 hypothetical protein FLJ11282 /FL=gb:NM_018380.1" NM_018380 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 DDX28 55794 NM_018380 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203786_s_at NM_003287 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003287.1 /DEF=Homo sapiens tumor protein D52-like 1 (TPD52L1), mRNA. /FEA=mRNA /GEN=TPD52L1 /PROD=tumor protein D52-like 1 /DB_XREF=gi:4507640 /UG=Hs.16611 tumor protein D52-like 1 /FL=gb:U44427.1 gb:NM_003287.1" NM_003287 tumor protein D52-like 1 TPD52L1 7164 NM_001003395 /// NM_001003396 /// NM_001003397 /// NM_001292026 /// NM_003287 /// XM_005267121 /// XM_005267122 /// XM_005267123 /// XM_005267124 /// XM_006715556 /// XM_006715557 /// XM_006715558 0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0006309 // apoptotic DNA fragmentation // inferred from direct assay /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0097194 // execution phase of apoptosis // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 203787_at NM_012446 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012446.1 /DEF=Homo sapiens single-stranded-DNA-binding protein (SSBP2), mRNA. /FEA=mRNA /GEN=SSBP2 /PROD=single-stranded-DNA-binding protein /DB_XREF=gi:7106422 /UG=Hs.169833 single-stranded-DNA-binding protein /FL=gb:AL080076.1 gb:AF161465.1 gb:NM_012446.1" NM_012446 single-stranded DNA binding protein 2 SSBP2 23635 NM_001256732 /// NM_001256733 /// NM_001256734 /// NM_001256735 /// NM_001256736 /// NM_012446 "0006355 // regulation of transcription, DNA-templated // non-traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 203788_s_at AI962897 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI962897 /FEA=EST /DB_XREF=gi:5755610 /DB_XREF=est:wt24e04.x1 /CLONE=IMAGE:2508414 /UG=Hs.171921 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C /FL=gb:AB000220.1 gb:NM_006379.1" AI962897 "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C" SEMA3C 10512 NM_006379 /// XM_005250113 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003215 // cardiac right ventricle morphogenesis // inferred from electronic annotation /// 0003350 // pulmonary myocardium development // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 203789_s_at NM_006379 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006379.1 /DEF=Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C), mRNA. /FEA=mRNA /GEN=SEMA3C /PROD=sema domain, immunoglobulin domain (Ig), shortbasic domain, secreted, (semaphorin) 3C /DB_XREF=gi:5454047 /UG=Hs.171921 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C /FL=gb:AB000220.1 gb:NM_006379.1" NM_006379 "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C" SEMA3C 10512 NM_006379 /// XM_005250113 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0003215 // cardiac right ventricle morphogenesis // inferred from electronic annotation /// 0003350 // pulmonary myocardium development // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0021915 // neural tube development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0060174 // limb bud formation // inferred from electronic annotation /// 0060666 // dichotomous subdivision of terminal units involved in salivary gland branching // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation 203790_s_at N54448 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N54448 /FEA=EST /DB_XREF=gi:1195768 /DB_XREF=est:yv36h05.s1 /CLONE=IMAGE:244857 /UG=Hs.18426 translational inhibitor protein p14.5 /FL=gb:NM_005836.1 N54448 heat-responsive protein 12 HRSP12 10247 NM_005836 0006449 // regulation of translational termination // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019239 // deaminase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203791_at NM_005509 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005509.2 /DEF=Homo sapiens Dmx-like 1 (DMXL1), mRNA. /FEA=mRNA /GEN=DMXL1 /PROD=Dmx-like 1 /DB_XREF=gi:9961348 /UG=Hs.181042 Dmx-like 1 /FL=gb:NM_005509.2" NM_005509 Dmx-like 1 DMXL1 1657 NM_001290321 /// NM_001290322 /// NM_005509 /// XM_005271909 /// XM_005271910 /// XM_005271911 /// XM_005271912 /// XM_005271913 /// XM_006714560 0005515 // protein binding // inferred from electronic annotation 203792_x_at BC004858 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC004858.1 /DEF=Homo sapiens, zinc finger protein 144 (Mel-18), clone MGC:10336, mRNA, complete cds. /FEA=mRNA /PROD=zinc finger protein 144 (Mel-18) /DB_XREF=gi:13436061 /UG=Hs.184669 zinc finger protein 144 (Mel-18) /FL=gb:BC004858.1 gb:D13969.1 gb:NM_007144.1" BC004858 polycomb group ring finger 2 PCGF2 7703 NM_007144 /// XM_005257640 /// XM_005257641 /// XM_005257642 /// XM_006722071 /// XM_006725342 /// XM_006725343 /// XM_006725344 /// XM_006725345 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203793_x_at NM_007144 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007144.1 /DEF=Homo sapiens zinc finger protein 144 (Mel-18) (ZNF144), mRNA. /FEA=mRNA /GEN=ZNF144 /PROD=zinc finger protein 144 (Mel-18) /DB_XREF=gi:6005963 /UG=Hs.184669 zinc finger protein 144 (Mel-18) /FL=gb:BC004858.1 gb:D13969.1 gb:NM_007144.1" NM_007144 polycomb group ring finger 2 PCGF2 7703 NM_007144 /// XM_005257640 /// XM_005257641 /// XM_005257642 /// XM_006722071 /// XM_006725342 /// XM_006725343 /// XM_006725344 /// XM_006725345 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from direct assay /// 0001739 // sex chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from direct assay /// 0035102 // PRC1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203794_at NM_014826 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014826.1 /DEF=Homo sapiens KIAA0451 gene product (KIAA0451), mRNA. /FEA=mRNA /GEN=KIAA0451 /PROD=KIAA0451 gene product /DB_XREF=gi:7662135 /UG=Hs.18586 KIAA0451 gene product /FL=gb:AB007920.1 gb:NM_014826.1" NM_014826 CDC42 binding protein kinase alpha (DMPK-like) CDC42BPA 8476 NM_003607 /// NM_014826 /// XM_005273317 /// XM_005273318 /// XM_005273320 /// XM_005273321 /// XM_005273322 /// XM_005273323 /// XM_005273324 /// XM_006711834 /// XM_006711835 /// XM_006711836 /// XM_006711837 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007097 // nuclear migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from mutant phenotype /// 0031032 // actomyosin structure organization // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0042641 // actomyosin // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005083 // small GTPase regulator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation" 203795_s_at NM_020993 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020993.1 /DEF=Homo sapiens B-cell CLLlymphoma 7A (BCL7A), mRNA. /FEA=mRNA /GEN=BCL7A /PROD=B-cell CLLlymphoma 7A /DB_XREF=gi:10337612 /UG=Hs.211563 B-cell CLLlymphoma 7A /FL=gb:NM_020993.1" NM_020993 B-cell CLL/lymphoma 7A BCL7A 605 NM_001024808 /// NM_020993 "0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement" 203796_s_at AI950380 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI950380 /FEA=EST /DB_XREF=gi:5742690 /DB_XREF=est:wp10g03.x1 /CLONE=IMAGE:2464468 /UG=Hs.211563 B-cell CLLlymphoma 7A /FL=gb:NM_020993.1 AI950380 B-cell CLL/lymphoma 7A BCL7A 605 NM_001024808 /// NM_020993 "0045892 // negative regulation of transcription, DNA-templated // non-traceable author statement" 203797_at AF039555 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF039555.1 /DEF=Homo sapiens visinin-like protein 1 (VSNL1) mRNA, complete cds. /FEA=mRNA /GEN=VSNL1 /PROD=visinin-like protein 1 /DB_XREF=gi:4104813 /UG=Hs.2288 visinin-like 1 /FL=gb:AF039555.1 gb:NM_003385.1 gb:AB001104.1 gb:U14747.1" AF039555 visinin-like 1 VSNL1 7447 NM_003385 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203798_s_at NM_003385 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003385.1 /DEF=Homo sapiens visinin-like 1 (VSNL1), mRNA. /FEA=mRNA /GEN=VSNL1 /PROD=visinin-like 1 /DB_XREF=gi:4507904 /UG=Hs.2288 visinin-like 1 /FL=gb:AF039555.1 gb:NM_003385.1 gb:AB001104.1 gb:U14747.1" NM_003385 visinin-like 1 VSNL1 7447 NM_003385 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203799_at NM_014880 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014880.1 /DEF=Homo sapiens KIAA0022 gene product (KIAA0022), mRNA. /FEA=mRNA /GEN=KIAA0022 /PROD=KIAA0022 gene product /DB_XREF=gi:7661867 /UG=Hs.2441 KIAA0022 gene product /FL=gb:D14664.1 gb:NM_014880.1" NM_014880 CD302 molecule /// lymphocyte antigen 75 /// LY75-CD302 readthrough CD302 /// LY75 /// LY75-CD302 4065 /// 9936 /// 100526664 NM_001198759 /// NM_001198760 /// NM_001198763 /// NM_001198764 /// NM_002349 /// NM_014880 0006897 // endocytosis // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from electronic annotation /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004872 // receptor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203800_s_at BG254653 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG254653 /FEA=EST /DB_XREF=gi:12764469 /DB_XREF=est:602368621F1 /CLONE=IMAGE:4476773 /UG=Hs.247324 hypothetical protein LOC63931 /FL=gb:NM_022100.1 BG254653 mitochondrial ribosomal protein S14 MRPS14 63931 NM_022100 /// NR_037606 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 203801_at AA013164 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA013164 /FEA=EST /DB_XREF=gi:1474190 /DB_XREF=est:ze35e12.s1 /CLONE=IMAGE:361006 /UG=Hs.247324 hypothetical protein LOC63931 /FL=gb:NM_022100.1 AA013164 mitochondrial ribosomal protein S14 MRPS14 63931 NM_022100 /// NR_037606 0006412 // translation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005761 // mitochondrial ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0003735 // structural constituent of ribosome // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 203802_x_at NM_018044 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018044.1 /DEF=Homo sapiens hypothetical protein FLJ10267 (FLJ10267), mRNA. /FEA=mRNA /GEN=FLJ10267 /PROD=hypothetical protein FLJ10267 /DB_XREF=gi:8922321 /UG=Hs.272820 hypothetical protein FLJ10267 /FL=gb:NM_018044.1" NM_018044 "NOP2/Sun domain family, member 5" NSUN5 55695 NM_001168347 /// NM_001168348 /// NM_018044 /// NM_148956 /// XM_005277604 /// XR_242255 0032259 // methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203803_at N45309 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N45309 /FEA=EST /DB_XREF=gi:1186475 /DB_XREF=est:yz17b09.s1 /CLONE=IMAGE:283289 /UG=Hs.278627 prenylcysteine lyase /FL=gb:AF181490.1 gb:NM_016297.1 N45309 prenylcysteine oxidase 1 PCYOX1 51449 NM_016297 0006821 // chloride transport // inferred from electronic annotation /// 0030327 // prenylated protein catabolic process // inferred from direct assay /// 0030327 // prenylated protein catabolic process // non-traceable author statement /// 0030328 // prenylcysteine catabolic process // inferred from electronic annotation /// 0030329 // prenylcysteine metabolic process // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0001735 // prenylcysteine oxidase activity // inferred from direct assay /// 0008555 // chloride-transporting ATPase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016670 // oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor // inferred from electronic annotation" 203804_s_at NM_006107 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006107.1 /DEF=Homo sapiens acid-inducible phosphoprotein (OA48-18), mRNA. /FEA=mRNA /GEN=OA48-18 /PROD=acid-inducible phosphoprotein /DB_XREF=gi:5174618 /UG=Hs.278670 acid-inducible phosphoprotein /FL=gb:AF069250.1 gb:NM_006107.1" NM_006107 LUC7-like 3 (S. cerevisiae) LUC7L3 51747 NM_006107 /// NM_016424 /// XM_005257448 /// XM_005257449 /// XM_005257450 /// XM_005257451 /// XM_005257452 /// XM_005257454 /// XM_005257455 /// XM_006721943 /// XR_243663 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005685 // U1 snRNP // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 203805_s_at AW083279 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW083279 /FEA=EST /DB_XREF=gi:6038431 /DB_XREF=est:xc07f04.x1 /CLONE=IMAGE:2583583 /UG=Hs.284153 Fanconi anemia, complementation group A /FL=gb:NM_000135.1" AW083279 "Fanconi anemia, complementation group A" FANCA 2175 NM_000135 /// NM_001018112 /// NM_001286167 /// XM_005256294 /// XM_006721167 /// XM_006721168 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203806_s_at NM_000135 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000135.1 /DEF=Homo sapiens Fanconi anemia, complementation group A (FANCA), mRNA. /FEA=mRNA /GEN=FANCA /PROD=Fanconi anemia, complementation group A /DB_XREF=gi:4503654 /UG=Hs.284153 Fanconi anemia, complementation group A /FL=gb:NM_000135.1" NM_000135 "Fanconi anemia, complementation group A" FANCA 2175 NM_000135 /// NM_001018112 /// NM_001286167 /// XM_005256294 /// XM_006721167 /// XM_006721168 0006281 // DNA repair // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008585 // female gonad development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203807_x_at NM_020991 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020991.2 /DEF=Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA. /FEA=mRNA /GEN=CSH2 /PROD=chorionic somatomammotropin hormone 2, isoform 1precursor /DB_XREF=gi:12408690 /UG=Hs.306155 chorionic somatomammotropin hormone 2 /FL=gb:NM_020991.2 gb:BC002717.1" NM_020991 chorionic somatomammotropin hormone 1 (placental lactogen) /// chorionic somatomammotropin hormone 2 /// chorionic somatomammotropin hormone-like 1 /// growth hormone 1 CSH1 /// CSH2 /// CSHL1 /// GH1 1442 /// 1443 /// 1444 /// 2688 NM_000515 /// NM_001317 /// NM_001318 /// NM_020991 /// NM_022559 /// NM_022560 /// NM_022561 /// NM_022562 /// NM_022579 /// NM_022580 /// NM_022581 /// NM_022640 /// NM_022641 /// NM_022644 /// NM_022645 /// XM_005257218 /// XM_005257219 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007565 // female pregnancy // traceable author statement /// 0010535 // positive regulation of activation of JAK2 kinase activity // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0015758 // glucose transport // inferred from direct assay /// 0032355 // response to estradiol // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from direct assay /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // traceable author statement /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0060396 // growth hormone receptor signaling pathway // inferred from direct assay /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070977 // bone maturation // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay 0005131 // growth hormone receptor binding // inferred from direct assay /// 0005131 // growth hormone receptor binding // inferred from physical interaction /// 0005148 // prolactin receptor binding // inferred from physical interaction /// 0005179 // hormone activity // inferred from electronic annotation /// 0005179 // hormone activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203808_at M95936 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:M95936.1 /DEF=Human protein-serinethreonine (AKT2) mRNA, complete cds. /FEA=mRNA /GEN=AKT2 /PROD=protein serinethreonine kinase /DB_XREF=gi:178325 /UG=Hs.326445 v-akt murine thymoma viral oncogene homolog 2 /FL=gb:M95936.1 gb:NM_001626.2" M95936 203809_s_at AA769075 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA769075 /FEA=EST /DB_XREF=gi:2820313 /DB_XREF=est:oa74c11.s1 /CLONE=IMAGE:1318004 /UG=Hs.326445 v-akt murine thymoma viral oncogene homolog 2 /FL=gb:M95936.1 gb:NM_001626.2 AA769075 v-akt murine thymoma viral oncogene homolog 2 AKT2 208 NM_001243027 /// NM_001243028 /// NM_001626 /// XM_006723081 /// XM_006723082 /// XM_006723083 /// XM_006723084 /// XM_006723085 0001934 // positive regulation of protein phosphorylation // inferred from sequence or structural similarity /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from mutant phenotype /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // traceable author statement /// 0031340 // positive regulation of vesicle fusion // inferred from sequence or structural similarity /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032287 // peripheral nervous system myelin maintenance // inferred from electronic annotation /// 0032859 // activation of Ral GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0045444 // fat cell differentiation // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0046328 // regulation of JNK cascade // inferred from electronic annotation /// 0060644 // mammary gland epithelial cell differentiation // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0065002 // intracellular protein transmembrane transport // inferred from sequence or structural similarity /// 0071156 // regulation of cell cycle arrest // traceable author statement /// 0072659 // protein localization to plasma membrane // inferred from electronic annotation /// 0090314 // positive regulation of protein targeting to membrane // inferred from sequence or structural similarity /// 2000147 // positive regulation of cell motility // inferred from mutant phenotype /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 203810_at BG252490 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG252490 /FEA=EST /DB_XREF=gi:12762406 /DB_XREF=est:602366225F1 /CLONE=IMAGE:4474279 /UG=Hs.41693 DnaJ (Hsp40) homolog, subfamily B, member 4 /FL=gb:U40992.2 gb:NM_007034.2" BG252490 "DnaJ (Hsp40) homolog, subfamily B, member 4" DNAJB4 11080 NM_007034 /// XM_005270397 /// XM_006710308 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0009408 // response to heat // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 203811_s_at NM_007034 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007034.2 /DEF=Homo sapiens DnaJ-like heat shock protein 40 (HLJ1), mRNA. /FEA=mRNA /GEN=HLJ1 /PROD=DnaJ-like heat shock protein 40 /DB_XREF=gi:6631084 /UG=Hs.41693 DnaJ (Hsp40) homolog, subfamily B, member 4 /FL=gb:U40992.2 gb:NM_007034.2" NM_007034 "DnaJ (Hsp40) homolog, subfamily B, member 4" DNAJB4 11080 NM_007034 /// XM_005270397 /// XM_006710308 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0009408 // response to heat // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 203812_at AB011538 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB011538.1 /DEF=Homo sapiens mRNA for MEGF5, partial cds. /FEA=mRNA /GEN=MEGF5 /PROD=MEGF5 /DB_XREF=gi:3449301 /UG=Hs.57929 slit (Drosophila) homolog 3 /FL=gb:NM_003062.1 gb:AB017169.1" AB011538 slit homolog 3 (Drosophila) SLIT3 6586 NM_001271946 /// NM_003062 /// XR_427809 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0035385 // Roundabout signaling pathway // inferred from mutant phenotype /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051414 // response to cortisol // inferred from expression pattern /// 0061364 // apoptotic process involved in luteolysis // inferred from expression pattern /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction 203813_s_at NM_003062 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003062.1 /DEF=Homo sapiens slit (Drosophila) homolog 3 (SLIT3), mRNA. /FEA=mRNA /GEN=SLIT3 /PROD=slit (Drosophila) homolog 3 /DB_XREF=gi:11321570 /UG=Hs.57929 slit (Drosophila) homolog 3 /FL=gb:NM_003062.1 gb:AB017169.1" NM_003062 slit homolog 3 (Drosophila) SLIT3 6586 NM_001271946 /// NM_003062 /// XR_427809 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0035385 // Roundabout signaling pathway // inferred from mutant phenotype /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051414 // response to cortisol // inferred from expression pattern /// 0061364 // apoptotic process involved in luteolysis // inferred from expression pattern /// 0070100 // negative regulation of chemokine-mediated signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction 203814_s_at NM_000904 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000904.1 /DEF=Homo sapiens NAD(P)H menadione oxidoreductase 2, dioxin-inducible (NMOR2), mRNA. /FEA=mRNA /GEN=NMOR2 /PROD=NAD(P)H menadione oxidoreductase 2,dioxin-inducible /DB_XREF=gi:4505416 /UG=Hs.73956 NAD(P)H menadione oxidoreductase 2, dioxin-inducible /FL=gb:J02888.1 gb:NM_000904.1" NM_000904 "NAD(P)H dehydrogenase, quinone 2" NQO2 4835 NM_000904 /// NM_001290221 /// NM_001290222 /// XM_005249147 /// XM_005249148 /// XM_005249149 /// XM_005249150 /// XM_005249151 /// XM_005249152 /// XM_006715100 /// XM_006715101 0007613 // memory // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001512 // dihydronicotinamide riboside quinone reductase activity // inferred from electronic annotation /// 0008753 // NADPH dehydrogenase (quinone) activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203815_at NM_000853 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000853.1 /DEF=Homo sapiens glutathione S-transferase theta 1 (GSTT1), mRNA. /FEA=mRNA /GEN=GSTT1 /PROD=glutathione S-transferase theta 1 /DB_XREF=gi:4504184 /UG=Hs.77490 glutathione S-transferase theta 1 /FL=gb:NM_000853.1" NM_000853 glutathione S-transferase theta 1 GSTT1 2952 NM_000853 /// NM_001293807 /// NM_001293808 /// NM_001293809 /// NM_001293810 /// NM_001293811 /// NM_001293812 /// NM_001293813 /// NM_001293814 /// XM_005261587 /// XM_005261588 /// XM_005261589 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 203816_at NM_001929 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001929.1 /DEF=Homo sapiens deoxyguanosine kinase (DGUOK), mRNA. /FEA=mRNA /GEN=DGUOK /PROD=deoxyguanosine kinase /DB_XREF=gi:4503318 /UG=Hs.77494 deoxyguanosine kinase /FL=gb:U41668.1 gb:NM_001929.1" NM_001929 deoxyguanosine kinase DGUOK 1716 NM_001929 /// NM_080915 /// NM_080916 /// NM_080917 /// NM_080918 /// XM_005264173 /// XM_005264174 /// XR_244926 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008617 // guanosine metabolic process // traceable author statement /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046070 // dGTP metabolic process // inferred from electronic annotation /// 0046122 // purine deoxyribonucleoside metabolic process // inferred from direct assay /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004138 // deoxyguanosine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded" 203817_at W93728 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:W93728 /FEA=EST /DB_XREF=gi:1422918 /DB_XREF=est:zd96a11.s1 /CLONE=IMAGE:357308 /UG=Hs.77890 guanylate cyclase 1, soluble, beta 3 /FL=gb:NM_000857.1" W93728 "guanylate cyclase 1, soluble, beta 3" GUCY1B3 2983 NM_000857 /// NM_001291951 /// NM_001291952 /// NM_001291953 /// NM_001291954 /// NM_001291955 /// XM_005262959 0006182 // cGMP biosynthetic process // inferred from electronic annotation /// 0007263 // nitric oxide mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation "0005737 // cytoplasm // inferred from direct assay /// 0008074 // guanylate cyclase complex, soluble // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation" 0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0043167 // ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from electronic annotation 203818_s_at NM_006802 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006802.1 /DEF=Homo sapiens splicing factor 3a, subunit 3, 60kD (SF3A3), mRNA. /FEA=mRNA /GEN=SF3A3 /PROD=splicing factor 3a, subunit 3, 60kD /DB_XREF=gi:5803166 /UG=Hs.77897 splicing factor 3a, subunit 3, 60kD /FL=gb:BC002395.1 gb:U08815.1 gb:NM_006802.1" NM_006802 "splicing factor 3a, subunit 3, 60kDa" SF3A3 10946 NM_006802 /// XM_005270390 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0000389 // mRNA 3'-splice site recognition // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203819_s_at AU160004 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU160004 /FEA=EST /DB_XREF=gi:11021525 /DB_XREF=est:AU160004 /CLONE=Y79AA1000871 /UG=Hs.79440 IGF-II mRNA-binding protein 3 /FL=gb:U97188.1 gb:U76705.1 gb:AF117108.1 gb:NM_006547.1 AU160004 insulin-like growth factor 2 mRNA binding protein 3 IGF2BP3 10643 NM_006547 /// XM_006715638 /// XM_006715639 0006412 // translation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0042035 // regulation of cytokine biosynthetic process // inferred by curator /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from sequence or structural similarity /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 203820_s_at NM_006547 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006547.1 /DEF=Homo sapiens IGF-II mRNA-binding protein 3 (KOC1), mRNA. /FEA=mRNA /GEN=KOC1 /PROD=IGF-II mRNA-binding protein 3 /DB_XREF=gi:5729900 /UG=Hs.79440 IGF-II mRNA-binding protein 3 /FL=gb:U97188.1 gb:U76705.1 gb:AF117108.1 gb:NM_006547.1" NM_006547 insulin-like growth factor 2 mRNA binding protein 3 IGF2BP3 10643 NM_006547 /// XM_006715638 /// XM_006715639 0006412 // translation // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0042035 // regulation of cytokine biosynthetic process // inferred by curator /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0045182 // translation regulator activity // inferred from sequence or structural similarity /// 0048027 // mRNA 5'-UTR binding // inferred from direct assay 203821_at NM_001945 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001945.1 /DEF=Homo sapiens diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) (DTR), mRNA. /FEA=mRNA /GEN=DTR /PROD=diphtheria toxin receptor (heparin-bindingepidermal growth factor-like growth factor) /DB_XREF=gi:4503412 /UG=Hs.799 diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) /FL=gb:M60278.1 gb:NM_001945.1" NM_001945 heparin-binding EGF-like growth factor HBEGF 1839 NM_001945 "0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051545 // negative regulation of elastin biosynthetic process // inferred from electronic annotation /// 0051549 // positive regulation of keratinocyte migration // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0090303 // positive regulation of wound healing // inferred from mutant phenotype" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from sequence or structural similarity /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005154 // epidermal growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from direct assay /// 0008201 // heparin binding // inferred from mutant phenotype 203822_s_at NM_006874 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006874.1 /DEF=Homo sapiens E74-like factor 2 (ets domain transcription factor) (ELF2), mRNA. /FEA=mRNA /GEN=ELF2 /PROD=new Ets-related factor /DB_XREF=gi:6857815 /UG=Hs.82143 E74-like factor 2 (ets domain transcription factor) /FL=gb:U43189.1 gb:NM_006874.1" NM_006874 E74-like factor 2 (ets domain transcription factor) ELF2 1998 NM_001276457 /// NM_001276458 /// NM_001276459 /// NM_006874 /// NM_201999 /// XM_005262803 /// XM_005262804 /// XM_005262805 /// XM_005262806 /// XM_006714128 /// XM_006714129 /// XM_006714130 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0030154 // cell differentiation // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203823_at NM_021106 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021106.1 /DEF=Homo sapiens regulator of G-protein signalling 3 (RGS3), mRNA. /FEA=mRNA /GEN=RGS3 /PROD=regulator of G-protein signalling 3 /DB_XREF=gi:10864074 /UG=Hs.82294 regulator of G-protein signalling 3 /FL=gb:NM_021106.1 gb:U27655.1" NM_021106 regulator of G-protein signaling 3 RGS3 5998 NM_001276260 /// NM_001276261 /// NM_001276262 /// NM_001282922 /// NM_001282923 /// NM_017790 /// NM_130795 /// NM_134427 /// NM_144488 /// NM_144489 /// XM_006717219 /// XM_006717220 /// XM_006717221 /// XM_006717222 /// XM_006717223 /// XM_006717224 /// XM_006717225 /// XM_006717226 /// XM_006717227 /// XM_006717228 /// XM_006717229 /// XM_006717230 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 203824_at NM_004616 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004616.1 /DEF=Homo sapiens transmembrane 4 superfamily member 3 (TM4SF3), mRNA. /FEA=mRNA /GEN=TM4SF3 /PROD=transmembrane 4 superfamily member 3 /DB_XREF=gi:4759237 /UG=Hs.84072 transmembrane 4 superfamily member 3 /FL=gb:BC005246.1 gb:NM_004616.1" NM_004616 tetraspanin 8 TSPAN8 7103 NM_004616 /// XM_006719583 0006486 // protein glycosylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030195 // negative regulation of blood coagulation // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement 203825_at NM_007371 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007371.2 /DEF=Homo sapiens bromodomain-containing 3 (BRD3), mRNA. /FEA=mRNA /GEN=BRD3 /PROD=bromodomain-containing protein 3 /DB_XREF=gi:12408642 /UG=Hs.86896 bromodomain-containing 3 /FL=gb:NM_007371.2 gb:D26362.1" NM_007371 bromodomain containing 3 BRD3 8019 NM_007371 /// XM_005272214 /// XM_006717291 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003682 // chromatin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0070577 // lysine-acetylated histone binding // inferred from direct assay 203826_s_at NM_004910 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004910.1 /DEF=Homo sapiens phosphatidylinositol transfer protein, membrane-associated (PITPNM), mRNA. /FEA=mRNA /GEN=PITPNM /PROD=phosphatidylinositol transfer protein,membrane-associated /DB_XREF=gi:4758925 /UG=Hs.93837 phosphatidylinositol transfer protein, membrane-associated /FL=gb:NM_004910.1" NM_004910 "phosphatidylinositol transfer protein, membrane-associated 1" PITPNM1 9600 NM_001130848 /// NM_004910 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0007602 // phototransduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015914 // phospholipid transport // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 203827_at NM_017983 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017983.1 /DEF=Homo sapiens hypothetical protein FLJ10055 (FLJ10055), mRNA. /FEA=mRNA /GEN=FLJ10055 /PROD=hypothetical protein FLJ10055 /DB_XREF=gi:8922207 /UG=Hs.9398 hypothetical protein FLJ10055 /FL=gb:NM_017983.1" NM_017983 "WD repeat domain, phosphoinositide interacting 1" WIPI1 55062 NM_017983 /// XM_005257497 "0000045 // autophagic vacuole assembly // not recorded /// 0006914 // autophagy // inferred from expression pattern /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0048203 // vesicle targeting, trans-Golgi to endosome // inferred from direct assay" 0000139 // Golgi membrane // traceable author statement /// 0000407 // pre-autophagosomal structure // inferred from direct assay /// 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay "0005102 // receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from direct assay /// 0032266 // phosphatidylinositol-3-phosphate binding // inferred from direct assay /// 0050681 // androgen receptor binding // inferred from direct assay /// 0080025 // phosphatidylinositol-3,5-bisphosphate binding // inferred from direct assay" 203828_s_at NM_004221 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004221.1 /DEF=Homo sapiens natural killer cell transcript 4 (NK4), mRNA. /FEA=mRNA /GEN=NK4 /PROD=natural killer cell transcript 4 /DB_XREF=gi:4758811 /UG=Hs.943 natural killer cell transcript 4 /FL=gb:M59807.1 gb:NM_004221.1" NM_004221 interleukin 32 IL32 9235 NM_001012631 /// NM_001012632 /// NM_001012633 /// NM_001012634 /// NM_001012635 /// NM_001012636 /// NM_001012718 /// NM_004221 /// XM_005255686 0006952 // defense response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203829_at NM_019040 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_019040.1 /DEF=Homo sapiens hypothetical protein (FLJ20498), mRNA. /FEA=mRNA /GEN=FLJ20498 /PROD=hypothetical protein /DB_XREF=gi:9506684 /UG=Hs.97925 hypothetical protein /FL=gb:AL136677.1 gb:NM_019040.1" NM_019040 elongator acetyltransferase complex subunit 4 ELP4 26610 NM_001288725 /// NM_001288726 /// NM_019040 /// XM_005252865 "0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // inferred by curator /// 0016573 // histone acetylation // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from direct assay" "0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008023 // transcription elongation factor complex // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from direct assay /// 0033588 // Elongator holoenzyme complex // inferred from direct assay" 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008607 // phosphorylase kinase regulator activity // inferred from direct assay 203830_at NM_022344 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022344.1 /DEF=Homo sapiens protein kinase Njmu-R1 (NJMU-R1), mRNA. /FEA=mRNA /GEN=NJMU-R1 /PROD=protein kinase Njmu-R1 /DB_XREF=gi:11641248 /UG=Hs.9800 protein kinase Njmu-R1 /FL=gb:AF305686.1 gb:NM_022344.1" NM_022344 chromosome 17 open reading frame 75 C17orf75 64149 NM_022344 /// XM_005258022 /// XM_005258023 /// XM_006722011 0007283 // spermatogenesis // non-traceable author statement 203831_at NM_014925 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014925.1 /DEF=Homo sapiens KIAA1002 protein (KIAA1002), mRNA. /FEA=mRNA /GEN=KIAA1002 /PROD=KIAA1002 protein /DB_XREF=gi:7662441 /UG=Hs.102483 KIAA1002 protein /FL=gb:AB023219.1 gb:AF113695.1 gb:NM_014925.1" NM_014925 R3H domain containing 2 R3HDM2 22864 NM_014925 /// XM_005268711 /// XM_005268715 /// XM_005268722 /// XM_005268724 /// XM_005268725 /// XM_005268727 /// XM_005268728 /// XM_005268729 /// XM_006719277 /// XM_006719278 /// XM_006719279 /// XM_006719280 /// XM_006719281 /// XM_006719282 /// XM_006719283 /// XM_006719284 /// XM_006719285 /// XM_006719286 /// XM_006719287 /// XM_006719288 /// XM_006719289 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 203832_at NM_003095 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003095.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide F (SNRPF), mRNA. /FEA=mRNA /GEN=SNRPF /PROD=small nuclear ribonucleoprotein polypeptide F /DB_XREF=gi:4507130 /UG=Hs.105465 small nuclear ribonucleoprotein polypeptide F /FL=gb:BC002505.1 gb:NM_003095.1" NM_003095 small nuclear ribonucleoprotein polypeptide F SNRPF 6636 NM_003095 "0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008334 // histone mRNA metabolic process // traceable author statement /// 0008380 // RNA splicing // inferred from mutant phenotype /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from direct assay /// 0005683 // U7 snRNP // inferred from direct assay /// 0005685 // U1 snRNP // inferred from direct assay /// 0005687 // U4 snRNP // inferred from direct assay /// 0005689 // U12-type spliceosomal complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // inferred from direct assay /// 0034709 // methylosome // inferred from direct assay /// 0034715 // pICln-Sm protein complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay 0003723 // RNA binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction 203833_s_at BF061845 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF061845 /FEA=EST /DB_XREF=gi:10820755 /DB_XREF=est:7k67g05.x1 /CLONE=IMAGE:3480752 /UG=Hs.14894 trans-Golgi network protein (46, 48, 51kD isoforms) /FL=gb:U62390.1 gb:NM_006464.1" BF061845 trans-golgi network protein 2 TGOLN2 10618 NM_001206840 /// NM_001206841 /// NM_001206844 /// NM_006464 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // traceable author statement 0005515 // protein binding // inferred from physical interaction 203834_s_at NM_006464 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006464.1 /DEF=Homo sapiens trans-Golgi network protein (46, 48, 51kD isoforms) (TGN51), mRNA. /FEA=mRNA /GEN=TGN51 /PROD=trans-Golgi network protein (46, 48, 51kDisoforms) /DB_XREF=gi:5454115 /UG=Hs.14894 trans-Golgi network protein (46, 48, 51kD isoforms) /FL=gb:U62390.1 gb:NM_006464.1" NM_006464 trans-golgi network protein 2 TGOLN2 10618 NM_001206840 /// NM_001206841 /// NM_001206844 /// NM_006464 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // traceable author statement 0005515 // protein binding // inferred from physical interaction 203835_at NM_005512 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005512.1 /DEF=Homo sapiens glycoprotein A repetitions predominant (GARP), mRNA. /FEA=mRNA /GEN=GARP /PROD=glycoprotein A repetitions predominantprecursor /DB_XREF=gi:5031706 /UG=Hs.151641 glycoprotein A repetitions predominant /FL=gb:Z24680.1 gb:NM_005512.1" NM_005512 leucine rich repeat containing 32 LRRC32 2615 NM_001128922 /// NM_005512 /// XM_005273902 /// XM_005273903 /// XR_428911 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0034170 // toll-like receptor 11 signaling pathway // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0046007 // negative regulation of activated T cell proliferation // inferred from electronic annotation /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 203836_s_at D84476 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D84476.1 /DEF=Homo sapiens mRNA for ASK1, complete cds. /FEA=mRNA /PROD=ASK1 /DB_XREF=gi:1805499 /UG=Hs.151988 mitogen-activated protein kinase kinase kinase 5 /FL=gb:U67156.1 gb:D84476.1 gb:NM_005923.2" D84476 mitogen-activated protein kinase kinase kinase 5 MAP3K5 4217 NM_005923 /// XM_005266990 /// XM_005266991 /// XM_005266992 /// XM_006715482 0000165 // MAPK cascade // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901216 // positive regulation of neuron death // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 1902911 // protein kinase complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203837_at NM_005923 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005923.2 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 5 (MAP3K5), mRNA. /FEA=mRNA /GEN=MAP3K5 /PROD=MAPERK kinase kinase 5 /DB_XREF=gi:6031181 /UG=Hs.151988 mitogen-activated protein kinase kinase kinase 5 /FL=gb:U67156.1 gb:D84476.1 gb:NM_005923.2" NM_005923 mitogen-activated protein kinase kinase kinase 5 MAP3K5 4217 NM_005923 /// XM_005266990 /// XM_005266991 /// XM_005266992 /// XM_006715482 0000165 // MAPK cascade // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0007254 // JNK cascade // inferred from direct assay /// 0007257 // activation of JUN kinase activity // traceable author statement /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from direct assay /// 0010941 // regulation of cell death // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045087 // innate immune response // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1901216 // positive regulation of neuron death // inferred from genetic interaction 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 1902911 // protein kinase complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203838_s_at AI146308 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI146308 /FEA=EST /DB_XREF=gi:3673990 /DB_XREF=est:qa03e05.x1 /CLONE=IMAGE:1685696 /UG=Hs.153937 activated p21cdc42Hs kinase /FL=gb:L13738.2 gb:NM_005781.2 AI146308 "tyrosine kinase, non-receptor, 2" TNK2 10188 NM_001010938 /// NM_005781 /// XM_005269268 /// XM_005269269 /// XM_005269270 /// XM_005269271 /// XM_005269272 /// XM_005269273 /// XM_005269274 /// XM_005269275 /// XM_006713460 /// XM_006713461 /// XM_006713462 /// XM_006713463 /// XM_006713464 /// XM_006713465 /// XM_006713466 /// XM_006713467 /// XM_006713468 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070436 // Grb2-EGFR complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from sequence or structural similarity" 203839_s_at NM_005781 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005781.2 /DEF=Homo sapiens activated p21cdc42Hs kinase (ACK1), mRNA. /FEA=mRNA /GEN=ACK1 /PROD=activated p21cdc42Hs kinase /DB_XREF=gi:8922074 /UG=Hs.153937 activated p21cdc42Hs kinase /FL=gb:L13738.2 gb:NM_005781.2" NM_005781 "tyrosine kinase, non-receptor, 2" TNK2 10188 NM_001010938 /// NM_005781 /// XM_005269268 /// XM_005269269 /// XM_005269270 /// XM_005269271 /// XM_005269272 /// XM_005269273 /// XM_005269274 /// XM_005269275 /// XM_006713460 /// XM_006713461 /// XM_006713462 /// XM_006713463 /// XM_006713464 /// XM_006713465 /// XM_006713466 /// XM_006713467 /// XM_006713468 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 2000369 // regulation of clathrin-mediated endocytosis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070436 // Grb2-EGFR complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from sequence or structural similarity" 203840_at NM_003666 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003666.1 /DEF=Homo sapiens basic leucine zipper nuclear factor 1 (JEM-1) (BLZF1), mRNA. /FEA=mRNA /GEN=BLZF1 /PROD=basic leucine zipper nuclear factor 1 (JEM-1) /DB_XREF=gi:4504804 /UG=Hs.158205 basic leucine zipper nuclear factor 1 (JEM-1) /FL=gb:U79751.1 gb:NM_003666.1" NM_003666 basic leucine zipper nuclear factor 1 BLZF1 8548 NM_003666 /// XM_005245561 0000278 // mitotic cell cycle // traceable author statement /// 0001558 // regulation of cell growth // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007030 // Golgi organization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0043001 // Golgi to plasma membrane protein transport // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005796 // Golgi lumen // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction 203841_x_at BG222594 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BG222594 /FEA=EST /DB_XREF=gi:12708115 /DB_XREF=est:naf78c05.x1 /CLONE=IMAGE:4170224 /UG=Hs.172740 microtubule-associated protein, RPEB family, member 3 /FL=gb:NM_012326.2 gb:AB025186.1" BG222594 "microtubule-associated protein, RP/EB family, member 3" MAPRE3 22924 NM_012326 /// XM_006711967 /// XM_006711968 "0007049 // cell cycle // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity 203842_s_at NM_012326 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012326.2 /DEF=Homo sapiens microtubule-associated protein, RPEB family, member 3 (MAPRE3), mRNA. /FEA=mRNA /GEN=MAPRE3 /PROD=microtubule-associated protein, RPEB family,member 3 /DB_XREF=gi:10800411 /UG=Hs.172740 microtubule-associated protein, RPEB family, member 3 /FL=gb:NM_012326.2 gb:AB025186.1" NM_012326 "microtubule-associated protein, RP/EB family, member 3" MAPRE3 22924 NM_012326 /// XM_006711967 /// XM_006711968 "0007049 // cell cycle // inferred from electronic annotation /// 0007049 // cell cycle // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005083 // small GTPase regulator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity 203843_at AA906056 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA906056 /FEA=EST /DB_XREF=gi:3041179 /DB_XREF=est:oj90d06.s1 /CLONE=IMAGE:1505579 /UG=Hs.173965 ribosomal protein S6 kinase, 90kD, polypeptide 3 /FL=gb:U08316.1 gb:NM_004586.1" AA906056 "ribosomal protein S6 kinase, 90kDa, polypeptide 3" RPS6KA3 6197 NM_004586 /// XM_005274573 /// XM_005274575 /// XM_005274576 /// XM_005274577 /// XM_006724505 /// XM_006724506 /// XM_006724507 0001501 // skeletal system development // traceable author statement /// 0002224 // toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043555 // regulation of translation in response to stress // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0043027 // cysteine-type endopeptidase inhibitor activity involved in apoptotic process // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 203844_at NM_000551 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000551.1 /DEF=Homo sapiens von Hippel-Lindau syndrome (VHL), mRNA. /FEA=mRNA /GEN=VHL /PROD=elogin binding protein /DB_XREF=gi:4507890 /UG=Hs.174007 von Hippel-Lindau syndrome /FL=gb:NM_000551.1" NM_000551 "von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase" VHL 7428 NM_000551 /// NM_198156 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0000902 // cell morphogenesis // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006508 // proteolysis // traceable author statement /// 0006950 // response to stress // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // non-traceable author statement /// 0045597 // positive regulation of cell differentiation // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050821 // protein stabilization // non-traceable author statement /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // traceable author statement /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0071456 // cellular response to hypoxia // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // non-traceable author statement /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction 203845_at AV727449 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV727449 /FEA=EST /DB_XREF=gi:10836870 /DB_XREF=est:AV727449 /CLONE=HTCAYG01 /UG=Hs.199061 p300CBP-associated factor /FL=gb:U57317.2 gb:NM_003884.2 AV727449 K(lysine) acetyltransferase 2B KAT2B 8850 NM_003884 /// XM_005265528 /// XR_245162 "0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006473 // protein acetylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010835 // regulation of protein ADP-ribosylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0018394 // peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation" 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000125 // PCAF complex // non-traceable author statement /// 0000776 // kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0031672 // A band // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation "0003712 // transcription cofactor activity // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from sequence or structural similarity /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction" 203846_at BC003154 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC003154.1 /DEF=Homo sapiens, TAT-INTERACTIVE PROTEIN, 72-KD, clone MGC:4116, mRNA, complete cds. /FEA=mRNA /PROD=TAT-INTERACTIVE PROTEIN, 72-KD /DB_XREF=gi:13111962 /UG=Hs.236218 TAT-INTERACTIVE PROTEIN, 72-KD /FL=gb:BC003154.1 gb:NM_012210.1 gb:U18543.1" BC003154 tripartite motif containing 32 TRIM32 22954 NM_001099679 /// NM_012210 /// XM_005251813 0000209 // protein polyubiquitination // inferred from direct assay /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0032897 // negative regulation of viral transcription // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from sequence or structural similarity /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045732 // positive regulation of protein catabolic process // inferred from sequence or structural similarity /// 0045787 // positive regulation of cell cycle // inferred from direct assay /// 0045862 // positive regulation of proteolysis // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 1902187 // negative regulation of viral release from host cell // inferred from direct assay /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000147 // positive regulation of cell motility // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005863 // striated muscle myosin thick filament // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // traceable author statement /// 0003723 // RNA binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0017022 // myosin binding // inferred from sequence or structural similarity /// 0030957 // Tat protein binding // traceable author statement /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043621 // protein self-association // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203847_s_at AW341501 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW341501 /FEA=EST /DB_XREF=gi:6838127 /DB_XREF=est:hd10e03.x1 /CLONE=IMAGE:2909116 /UG=Hs.25059 A kinase (PRKA) anchor protein 8 /FL=gb:NM_005858.1 AW341501 A kinase (PRKA) anchor protein 8 AKAP8 10270 NM_005858 /// XM_005259706 /// XR_244062 0006810 // transport // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0001939 // female pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203848_at AL050160 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL050160.1 /DEF=Homo sapiens mRNA; cDNA DKFZp586B1222 (from clone DKFZp586B1222); partial cds. /FEA=mRNA /GEN=DKFZp586B1222 /PROD=hypothetical protein /DB_XREF=gi:4884373 /UG=Hs.25059 A kinase (PRKA) anchor protein 8 /FL=gb:NM_005858.1 AL050160 A kinase (PRKA) anchor protein 8 AKAP8 10270 NM_005858 /// XM_005259706 /// XR_244062 0006810 // transport // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0001939 // female pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0034237 // protein kinase A regulatory subunit binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203849_s_at BG473130 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG473130 /FEA=EST /DB_XREF=gi:13405405 /DB_XREF=est:602515112F1 /CLONE=IMAGE:4646835 /UG=Hs.259873 axonal transport of synaptic vesicles /FL=gb:NM_004321.1 BG473130 kinesin family member 1A KIF1A 547 NM_001244008 /// NM_004321 /// XM_005247022 /// XM_005247023 /// XM_005247024 /// XM_005247026 /// XM_005247027 /// XM_005247028 /// XM_006712601 /// XM_006712602 /// XM_006712603 /// XM_006712604 /// XM_006712605 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203850_s_at NM_004321 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004321.1 /DEF=Homo sapiens axonal transport of synaptic vesicles (ATSV), mRNA. /FEA=mRNA /GEN=ATSV /PROD=axonal transport of synaptic vesicles /DB_XREF=gi:4757821 /UG=Hs.259873 axonal transport of synaptic vesicles /FL=gb:NM_004321.1" NM_004321 kinesin family member 1A KIF1A 547 NM_001244008 /// NM_004321 /// XM_005247022 /// XM_005247023 /// XM_005247024 /// XM_005247026 /// XM_005247027 /// XM_005247028 /// XM_006712601 /// XM_006712602 /// XM_006712603 /// XM_006712604 /// XM_006712605 0007018 // microtubule-based movement // inferred from electronic annotation /// 0008089 // anterograde axon cargo transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation 203851_at NM_002178 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002178.1 /DEF=Homo sapiens insulin-like growth factor binding protein 6 (IGFBP6), mRNA. /FEA=mRNA /GEN=IGFBP6 /PROD=insulin-like growth factor binding protein 6 /DB_XREF=gi:11321592 /UG=Hs.274313 insulin-like growth factor binding protein 6 /FL=gb:NM_002178.1 gb:BC003507.1 gb:BC005007.1 gb:M62402.1" NM_002178 insulin-like growth factor binding protein 6 IGFBP6 3489 NM_002178 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from electronic annotation 203852_s_at NM_000344 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000344.2 /DEF=Homo sapiens survival of motor neuron 1, telomeric (SMN1), transcript variant d, mRNA. /FEA=mRNA /GEN=SMN1 /PROD=survival of motor neuron 1, telomeric isoform d /DB_XREF=gi:13259515 /UG=Hs.288986 survival of motor neuron 1, telomeric /FL=gb:NM_000344.2 gb:U18423.1" NM_000344 "survival of motor neuron 1, telomeric /// survival of motor neuron 2, centromeric" SMN1 /// SMN2 6606 /// 6607 NM_000344 /// NM_017411 /// NM_022874 /// NM_022875 /// NM_022876 /// NM_022877 /// XM_005248575 /// XM_005276775 /// XM_006714677 0000245 // spliceosomal complex assembly // inferred from mutant phenotype /// 0000245 // spliceosomal complex assembly // non-traceable author statement /// 0000387 // spliceosomal snRNP assembly // inferred from direct assay /// 0000387 // spliceosomal snRNP assembly // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0034660 // ncRNA metabolic process // traceable author statement /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015030 // Cajal body // inferred from direct assay /// 0030018 // Z disc // inferred from electronic annotation /// 0032797 // SMN complex // inferred from direct assay /// 0034719 // SMN-Sm protein complex // inferred from direct assay /// 0097504 // Gemini of coiled bodies // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 203853_s_at NM_012296 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012296.1 /DEF=Homo sapiens GRB2-associated binding protein 2 (GAB2), mRNA. /FEA=mRNA /GEN=GAB2 /PROD=GRB2-associated binding protein 2 /DB_XREF=gi:6912459 /UG=Hs.30687 GRB2-associated binding protein 2 /FL=gb:AB011143.1 gb:NM_012296.1" NM_012296 GRB2-associated binding protein 2 GAB2 9846 NM_012296 /// NM_080491 /// XM_006718753 /// XR_428935 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009967 // positive regulation of signal transduction // inferred from reviewed computational analysis /// 0016477 // cell migration // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043306 // positive regulation of mast cell degranulation // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation "0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from direct assay /// 0005070 // SH3/SH2 adaptor activity // inferred from reviewed computational analysis /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from sequence or structural similarity /// 0043325 // phosphatidylinositol-3,4-bisphosphate binding // inferred from sequence or structural similarity" 203854_at NM_000204 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000204.1 /DEF=Homo sapiens I factor (complement) (IF), mRNA. /FEA=mRNA /GEN=IF /PROD=I factor (complement) /DB_XREF=gi:4504578 /UG=Hs.36602 I factor (complement) /FL=gb:J02770.1 gb:NM_000204.1" NM_000204 complement factor I CFI 3426 NM_000204 /// XM_005262975 /// XM_005262976 /// XM_006714209 /// XM_006714210 "0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement" 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203855_at NM_014969 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014969.1 /DEF=Homo sapiens KIAA0893 protein (KIAA0893), mRNA. /FEA=mRNA /GEN=KIAA0893 /PROD=KIAA0893 protein /DB_XREF=gi:7662363 /UG=Hs.3830 KIAA0893 protein /FL=gb:AB020700.1 gb:NM_014969.1" NM_014969 WD repeat domain 47 WDR47 22911 NM_001142550 /// NM_001142551 /// NM_014969 /// XM_006710460 /// XM_006710461 0007275 // multicellular organismal development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 203856_at NM_003384 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003384.1 /DEF=Homo sapiens vaccinia related kinase 1 (VRK1), mRNA. /FEA=mRNA /GEN=VRK1 /PROD=vaccinia related kinase 1 /DB_XREF=gi:4507902 /UG=Hs.48269 vaccinia related kinase 1 /FL=gb:AB000449.1 gb:NM_003384.1" NM_003384 vaccinia related kinase 1 VRK1 7443 NM_003384 /// XM_005268041 /// XM_006720247 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043987 // histone H3-S10 phosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0072355 // histone H3-T3 phosphorylation // inferred from direct assay /// 0090166 // Golgi disassembly // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005795 // Golgi stack // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031493 // nucleosomal histone binding // inferred from physical interaction /// 0035175 // histone kinase activity (H3-S10 specific) // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0072354 // histone kinase activity (H3-T3 specific) // inferred from direct assay" 203857_s_at NM_006810 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006810.1 /DEF=Homo sapiens for protein disulfide isomerase-related (PDIR), mRNA. /FEA=mRNA /GEN=PDIR /PROD=for protein disulfide isomerase-related /DB_XREF=gi:5803120 /UG=Hs.76901 for protein disulfide isomerase-related /FL=gb:D49490.1 gb:NM_006810.1" NM_006810 "microRNA 7110 /// protein disulfide isomerase family A, member 5" MIR7110 /// PDIA5 10954 /// 102465667 NM_006810 /// NR_028444 /// NR_106960 /// XR_427359 /// XR_427360 0006457 // protein folding // not recorded /// 0006457 // protein folding // traceable author statement /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement 0003756 // protein disulfide isomerase activity // not recorded /// 0003756 // protein disulfide isomerase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation 203858_s_at NM_001303 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001303.1 /DEF=Homo sapiens COX10 (yeast) homolog, cytochrome c oxidase assembly protein (heme A: farnesyltransferase) (COX10), mRNA. /FEA=mRNA /GEN=COX10 /PROD=COX10 (yeast) homolog, cytochrome c oxidaseassembly protein (heme A: farnesyltransferase) /DB_XREF=gi:4502978 /UG=Hs.77513 COX10 (yeast) homolog, cytochrome c oxidase assembly protein (heme A: farnesyltransferase) /FL=gb:BC000060.1 gb:NM_001303.1 gb:U09466.1" NM_001303 cytochrome c oxidase assembly homolog 10 (yeast) COX10 1352 NM_001303 /// XM_005256458 /// XM_005256459 "0000266 // mitochondrial fission // inferred from electronic annotation /// 0006123 // mitochondrial electron transport, cytochrome c to oxygen // inferred by curator /// 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006784 // heme a biosynthetic process // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0008535 // respiratory chain complex IV assembly // inferred from mutant phenotype /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0017004 // cytochrome complex assembly // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045333 // cellular respiration // inferred from genetic interaction /// 0048034 // heme O biosynthetic process // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // inferred from mutant phenotype" 0005739 // mitochondrion // inferred by curator /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from mutant phenotype /// 0004311 // farnesyltranstransferase activity // traceable author statement /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0008495 // protoheme IX farnesyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203859_s_at NM_002579 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002579.1 /DEF=Homo sapiens paralemmin (PALM), mRNA. /FEA=mRNA /GEN=PALM /PROD=paralemmin /DB_XREF=gi:4557041 /UG=Hs.78482 paralemmin /FL=gb:NM_002579.1" NM_002579 paralemmin PALM 5064 NM_001040134 /// NM_002579 /// XM_005259565 /// XM_005259566 /// XM_006722761 0006928 // cellular component movement // traceable author statement /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0008104 // protein localization // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from electronic annotation /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0060074 // synapse maturation // inferred from electronic annotation /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071257 // cellular response to electrical stimulus // inferred from electronic annotation /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031527 // filopodium membrane // inferred from direct assay /// 0032590 // dendrite membrane // inferred from electronic annotation /// 0032591 // dendritic spine membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0044309 // neuron spine // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031750 // D3 dopamine receptor binding // inferred from electronic annotation 203860_at NM_000282 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000282.1 /DEF=Homo sapiens propionyl Coenzyme A carboxylase, alpha polypeptide (PCCA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PCCA /PROD=Propionyl-Coenzyme A carboxylase, alphapolypeptide precursor /DB_XREF=gi:4557832 /UG=Hs.80741 propionyl Coenzyme A carboxylase, alpha polypeptide /FL=gb:BC000140.1 gb:NM_000282.1" NM_000282 "propionyl CoA carboxylase, alpha polypeptide" PCCA 5095 NM_000282 /// NM_001127692 /// NM_001178004 /// XM_005254059 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0019626 // short-chain fatty acid catabolic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0004658 // propionyl-CoA carboxylase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008716 // D-alanine-D-alanine ligase activity // inferred from electronic annotation /// 0009374 // biotin binding // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203861_s_at AU146889 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AU146889 /FEA=EST /DB_XREF=gi:11008410 /DB_XREF=est:AU146889 /CLONE=HEMBB1001793 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1" AU146889 "actinin, alpha 2" ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203862_s_at H16245 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:H16245 /FEA=EST /DB_XREF=gi:881065 /DB_XREF=est:ym13c09.s1 /CLONE=IMAGE:47741 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1" H16245 "actinin, alpha 2" ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203863_at W63731 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:W63731 /FEA=EST /DB_XREF=gi:1371311 /DB_XREF=est:zd30b05.s1 /CLONE=IMAGE:342129 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1" W63731 "actinin, alpha 2" ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203864_s_at NM_001103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001103.1 /DEF=Homo sapiens actinin, alpha 2 (ACTN2), mRNA. /FEA=mRNA /GEN=ACTN2 /PROD=actinin, alpha 2 /DB_XREF=gi:4501892 /UG=Hs.83672 actinin, alpha 2 /FL=gb:M86406.1 gb:NM_001103.1" NM_001103 "actinin, alpha 2" ACTN2 88 NM_001103 /// NM_001278343 /// NM_001278344 0002576 // platelet degranulation // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030035 // microspike assembly // inferred from direct assay /// 0030049 // muscle filament sliding // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0043267 // negative regulation of potassium ion transport // inferred from mutant phenotype /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051289 // protein homotetramerization // inferred from direct assay /// 1901017 // negative regulation of potassium ion transmembrane transporter activity // inferred from mutant phenotype /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000009 // negative regulation of protein localization to cell surface // inferred from mutant phenotype /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // non-traceable author statement /// 0005884 // actin filament // traceable author statement /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0030175 // filopodium // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0043197 // dendritic spine // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0030274 // LIM domain binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0031432 // titin binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation /// 0051373 // FATZ binding // inferred from direct assay /// 0070080 // titin Z domain binding // inferred from physical interaction 203865_s_at NM_015833 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015833.1 /DEF=Homo sapiens adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) (ADARB1), transcript variant DRABA2b, mRNA. /FEA=mRNA /GEN=ADARB1 /PROD=RNA-specific adenosine deaminase B1, isoformDRABA2b /DB_XREF=gi:7669476 /UG=Hs.85302 adenosine deaminase, RNA-specific, B1 (homolog of rat RED1) /FL=gb:U82121.1 gb:U76421.1 gb:NM_015833.1" NM_015833 "adenosine deaminase, RNA-specific, B1" ADARB1 104 NM_001033049 /// NM_001112 /// NM_001160230 /// NM_015833 /// NM_015834 /// NR_027672 /// NR_027673 /// NR_027674 /// NR_073200 /// XM_006723953 /// XM_006723954 /// XM_006723955 /// XM_006723956 /// XM_006723957 /// XM_006723958 0002376 // immune system process // inferred from electronic annotation /// 0006382 // adenosine to inosine editing // inferred from direct assay /// 0006382 // adenosine to inosine editing // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016553 // base conversion or substitution editing // inferred by curator /// 0016556 // mRNA modification // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay /// 0044387 // negative regulation of protein kinase activity by regulation of protein phosphorylation // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from direct assay /// 0003729 // mRNA binding // traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203866_at AJ005257 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AJ005257.1 /DEF=Homo sapiens partial mRNA for beta-transducin family protein (putative). /FEA=mRNA /DB_XREF=gi:3043442 /UG=Hs.85570 hypothetical protein similar to beta-transducin family /FL=gb:NM_018096.1 AJ005257 notchless homolog 1 (Drosophila) NLE1 54475 NM_001014445 /// NM_018096 /// XM_005257989 /// XM_005257992 /// XM_006721956 0001826 // inner cell mass cell differentiation // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2001268 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203867_s_at NM_018096 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018096.1 /DEF=Homo sapiens hypothetical protein similar to beta-transducin family (FLJ10458), mRNA. /FEA=mRNA /GEN=FLJ10458 /PROD=hypothetical protein similar to beta-transducinfamily /DB_XREF=gi:8922427 /UG=Hs.85570 hypothetical protein similar to beta-transducin family /FL=gb:NM_018096.1" NM_018096 notchless homolog 1 (Drosophila) NLE1 54475 NM_001014445 /// NM_018096 /// XM_005257989 /// XM_005257992 /// XM_006721956 0001826 // inner cell mass cell differentiation // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 2001268 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203868_s_at NM_001078 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001078.1 /DEF=Homo sapiens vascular cell adhesion molecule 1 (VCAM1), mRNA. /FEA=mRNA /GEN=VCAM1 /PROD=vascular cell adhesion molecule 1 /DB_XREF=gi:4507874 /UG=Hs.109225 vascular cell adhesion molecule 1 /FL=gb:M60335.1 gb:NM_001078.1" NM_001078 vascular cell adhesion molecule 1 VCAM1 7412 NM_001078 /// NM_001199834 /// NM_080682 0001666 // response to hypoxia // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0002544 // chronic inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007159 // leukocyte cell-cell adhesion // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009308 // amine metabolic process // inferred from direct assay /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0030183 // B cell differentiation // inferred by curator /// 0030198 // extracellular matrix organization // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035094 // response to nicotine // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0045471 // response to ethanol // inferred from electronic annotation /// 0050776 // regulation of immune response // traceable author statement /// 0050901 // leukocyte tethering or rolling // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060669 // embryonic placenta morphogenesis // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation 0002102 // podosome // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005769 // early endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005902 // microvillus // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071065 // alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation 0005178 // integrin binding // inferred from direct assay /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation /// 0008131 // primary amine oxidase activity // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 203869_at AK024318 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AK024318.1 /DEF=Homo sapiens cDNA FLJ14256 fis, clone PLACE1000007, weakly similar to PROBABLE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE R10E11.3 (EC 3.1.2.15). /FEA=mRNA /DB_XREF=gi:10436669 /UG=Hs.109268 hypothetical protein FLJ12552 /FL=gb:NM_022832.1" AK024318 ubiquitin specific peptidase 46 USP46 64854 NM_001134223 /// NM_001286767 /// NM_001286768 /// NM_022832 "0001662 // behavioral fear response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007610 // behavior // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity" 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 203870_at BE856374 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE856374 /FEA=EST /DB_XREF=gi:10369335 /DB_XREF=est:7f93f06.x1 /CLONE=IMAGE:3304547 /UG=Hs.109268 hypothetical protein FLJ12552 /FL=gb:NM_022832.1 BE856374 ubiquitin specific peptidase 46 USP46 64854 NM_001134223 /// NM_001286767 /// NM_001286768 /// NM_022832 "0001662 // behavioral fear response // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007610 // behavior // inferred from sequence or structural similarity /// 0016579 // protein deubiquitination // inferred from direct assay /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from sequence or structural similarity" 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation 203871_at NM_015670 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015670.1 /DEF=Homo sapiens sentrinSUMO-specific protease 3 (SENP3), mRNA. /FEA=mRNA /GEN=SENP3 /PROD=sentrinSUMO-specific protease 3 /DB_XREF=gi:7661681 /UG=Hs.118926 sentrinSUMO-specific protease 3 /FL=gb:AY008763.1 gb:AL050283.1 gb:NM_015670.1" NM_015670 SUMO1/sentrin/SMT3 specific peptidase 3 SENP3 26168 NM_015670 0006508 // proteolysis // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203872_at NM_001100 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001100.2 /DEF=Homo sapiens actin, alpha 1, skeletal muscle (ACTA1), mRNA. /FEA=mRNA /GEN=ACTA1 /PROD=alpha 1 actin precursor /DB_XREF=gi:5016087 /UG=Hs.1288 actin, alpha 1, skeletal muscle /FL=gb:NM_001100.2" NM_001100 "actin, alpha 1, skeletal muscle" ACTA1 58 NM_001100 0006936 // muscle contraction // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009991 // response to extracellular stimulus // inferred from electronic annotation /// 0010226 // response to lithium ion // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030240 // skeletal muscle thin filament assembly // inferred from mutant phenotype /// 0043503 // skeletal muscle fiber adaptation // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity 0001725 // stress fiber // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005865 // striated muscle thin filament // inferred from direct assay /// 0005884 // actin filament // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from mutant phenotype /// 0030017 // sarcomere // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0017022 // myosin binding // traceable author statement /// 0043531 // ADP binding // traceable author statement 203873_at M88163 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:M88163.1 /DEF=Human global transcription activator homologous sequence mRNA, complete cds. /FEA=mRNA /PROD=transcription activator /DB_XREF=gi:292495 /UG=Hs.152292 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 /FL=gb:M88163.1 gb:NM_003069.1" M88163 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" SMARCA1 6594 NM_001282874 /// NM_001282875 /// NM_003069 /// NM_139035 /// XM_005262461 /// XM_005262462 /// XM_006724782 "0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0090537 // CERF complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0070615 // nucleosome-dependent ATPase activity // inferred from direct assay" 203874_s_at NM_003069 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003069.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (SMARCA1), mRNA. /FEA=mRNA /GEN=SMARCA1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 1 /DB_XREF=gi:4507066 /UG=Hs.152292 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 /FL=gb:M88163.1 gb:NM_003069.1" NM_003069 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" SMARCA1 6594 NM_001282874 /// NM_001282875 /// NM_003069 /// NM_139035 /// XM_005262461 /// XM_005262462 /// XM_006724782 "0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0090537 // CERF complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0070615 // nucleosome-dependent ATPase activity // inferred from direct assay" 203875_at NM_003069 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003069.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (SMARCA1), mRNA. /FEA=mRNA /GEN=SMARCA1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily a, member 1 /DB_XREF=gi:4507066 /UG=Hs.152292 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 /FL=gb:M88163.1 gb:NM_003069.1" NM_003069 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" SMARCA1 6594 NM_001282874 /// NM_001282875 /// NM_003069 /// NM_139035 /// XM_005262461 /// XM_005262462 /// XM_006724782 "0000733 // DNA strand renaturation // inferred from direct assay /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007420 // brain development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 2000177 // regulation of neural precursor cell proliferation // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0016589 // NURF complex // inferred from direct assay /// 0090537 // CERF complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016817 // hydrolase activity, acting on acid anhydrides // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0031491 // nucleosome binding // inferred from electronic annotation /// 0036310 // annealing helicase activity // inferred from direct assay /// 0070615 // nucleosome-dependent ATPase activity // inferred from direct assay" 203876_s_at AI761713 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI761713 /FEA=EST /DB_XREF=gi:5177469 /DB_XREF=est:wg67d12.x1 /CLONE=IMAGE:2370167 /UG=Hs.155324 matrix metalloproteinase 11 (stromelysin 3) /FL=gb:NM_005940.2 AI761713 matrix metallopeptidase 11 (stromelysin 3) MMP11 4320 NM_005940 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203877_at NM_005940 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:NM_005940.2 /DEF=Homo sapiens matrix metalloproteinase 11 (stromelysin 3) (MMP11), mRNA. /FEA=mRNA /GEN=MMP11 /PROD=matrix metalloproteinase 11 preproprotein /DB_XREF=gi:13027795 /UG=Hs.155324 matrix metalloproteinase 11 (stromelysin 3) /FL=gb:NM_005940.2" NM_005940 203878_s_at NM_005940 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005940.2 /DEF=Homo sapiens matrix metalloproteinase 11 (stromelysin 3) (MMP11), mRNA. /FEA=mRNA /GEN=MMP11 /PROD=matrix metalloproteinase 11 preproprotein /DB_XREF=gi:13027795 /UG=Hs.155324 matrix metalloproteinase 11 (stromelysin 3) /FL=gb:NM_005940.2" NM_005940 matrix metallopeptidase 11 (stromelysin 3) MMP11 4320 NM_005940 0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0071711 // basement membrane organization // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203879_at U86453 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U86453.1 /DEF=Human phosphatidylinositol 3-kinase catalytic subunit p110delta mRNA, complete cds. /FEA=mRNA /PROD=phosphatidylinositol 3-kinase catalytic subunitp110delta /DB_XREF=gi:2317893 /UG=Hs.162808 phosphoinositide-3-kinase, catalytic, delta polypeptide /FL=gb:U86453.1 gb:NM_005026.1" U86453 "phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta" PIK3CD 5293 NM_005026 /// XM_005263473 /// XM_006710686 /// XM_006710687 /// XM_006710688 /// XM_006710689 /// XM_006710690 0001779 // natural killer cell differentiation // traceable author statement /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001816 // cytokine production // traceable author statement /// 0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002551 // mast cell chemotaxis // traceable author statement /// 0002679 // respiratory burst involved in defense response // traceable author statement /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010818 // T cell chemotaxis // traceable author statement /// 0014065 // phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030101 // natural killer cell activation // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // traceable author statement /// 0030593 // neutrophil chemotaxis // traceable author statement /// 0035747 // natural killer cell chemotaxis // traceable author statement /// 0035754 // B cell chemotaxis // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0043303 // mast cell degranulation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050853 // B cell receptor signaling pathway // traceable author statement /// 0060374 // mast cell differentiation // traceable author statement /// 0072672 // neutrophil extravasation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005942 // phosphatidylinositol 3-kinase complex // non-traceable author statement /// 0042629 // mast cell granule // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // not recorded" 203880_at NM_005694 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005694.1 /DEF=Homo sapiens COX17 (yeast) homolog, cytochrome c oxidase assembly protein (COX17), mRNA. /FEA=mRNA /GEN=COX17 /PROD=COX17 (yeast) homolog, cytochrome c oxidaseassembly protein /DB_XREF=gi:5031644 /UG=Hs.16297 COX17 (yeast) homolog, cytochrome c oxidase assembly protein /FL=gb:L77701.1 gb:NM_005694.1" NM_005694 COX17 cytochrome c oxidase copper chaperone /// popeye domain containing 2 COX17 /// POPDC2 10063 /// 64091 NM_005694 /// NM_022135 /// XM_005247698 /// XM_005247699 /// XR_241504 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0005507 // copper ion binding // traceable author statement /// 0016531 // copper chaperone activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203881_s_at NM_004010 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004010.1 /DEF=Homo sapiens dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272 (DMD), transcript variant Dp427p2, mRNA. /FEA=mRNA /GEN=DMD /PROD=dystrophin Dp427p2 isoform /DB_XREF=gi:5032314 /UG=Hs.169470 dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272 /FL=gb:NM_004010.1" NM_004010 dystrophin DMD 1756 NM_000109 /// NM_004006 /// NM_004007 /// NM_004009 /// NM_004010 /// NM_004011 /// NM_004012 /// NM_004013 /// NM_004014 /// NM_004015 /// NM_004016 /// NM_004017 /// NM_004018 /// NM_004019 /// NM_004020 /// NM_004021 /// NM_004022 /// NM_004023 /// XM_006724468 /// XM_006724469 /// XM_006724470 /// XM_006724471 /// XM_006724472 /// XM_006724473 /// XM_006724474 /// XM_006724475 /// XM_006724476 /// XR_430491 "0001954 // positive regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008065 // establishment of blood-nerve barrier // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010880 // regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0014809 // regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014819 // regulation of skeletal muscle contraction // inferred from sequence or structural similarity /// 0014904 // myotube cell development // inferred from electronic annotation /// 0021629 // olfactory nerve structural organization // inferred from electronic annotation /// 0030049 // muscle filament sliding // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0033137 // negative regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from mutant phenotype /// 0043043 // peptide biosynthetic process // inferred from direct assay /// 0043623 // cellular protein complex assembly // inferred from sequence or structural similarity /// 0044458 // motile cilium assembly // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0048747 // muscle fiber development // inferred from electronic annotation /// 0051647 // nucleus localization // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060857 // establishment of glial blood-brain barrier // inferred from electronic annotation /// 0086001 // cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0090287 // regulation of cellular response to growth factor stimulus // inferred from mutant phenotype /// 1901385 // regulation of voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 1902083 // negative regulation of peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 2000169 // regulation of peptidyl-cysteine S-nitrosylation // inferred from electronic annotation /// 2000651 // positive regulation of sodium ion transmembrane transporter activity // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // inferred from direct assay /// 0016010 // dystrophin-associated glycoprotein complex // non-traceable author statement /// 0016010 // dystrophin-associated glycoprotein complex // traceable author statement /// 0016013 // syntrophin complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // traceable author statement /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031527 // filopodium membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from direct assay /// 0043034 // costamere // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0044306 // neuron projection terminus // inferred from electronic annotation /// 0045121 // membrane raft // traceable author statement /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0002162 // dystroglycan binding // inferred from physical interaction /// 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // traceable author statement /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0008307 // structural constituent of muscle // traceable author statement /// 0017022 // myosin binding // inferred from direct assay /// 0017166 // vinculin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from sequence or structural similarity 203882_at NM_006084 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006084.1 /DEF=Homo sapiens interferon-stimulated transcription factor 3, gamma (48kD) (ISGF3G), mRNA. /FEA=mRNA /GEN=ISGF3G /PROD=interferon-stimulated transcription factor 3,gamma (48kD) /DB_XREF=gi:5174474 /UG=Hs.1706 interferon-stimulated transcription factor 3, gamma (48kD) /FL=gb:M87503.1 gb:NM_006084.1" NM_006084 interferon regulatory factor 9 IRF9 10379 NM_006084 "0000209 // protein polyubiquitination // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0023035 // CD40 signaling pathway // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0097039 // protein linear polyubiquitination // inferred from direct assay" 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity /// 0071797 // LUBAC complex // inferred from direct assay /// 0071797 // LUBAC complex // inferred from electronic annotation 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203883_s_at BG249608 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG249608 /FEA=EST /DB_XREF=gi:12759411 /DB_XREF=est:602319671F1 /CLONE=IMAGE:4415033 /UG=Hs.173656 KIAA0941 protein /FL=gb:AB023158.1 gb:NM_014904.1 BG249608 RAB11 family interacting protein 2 (class I) RAB11FIP2 22841 NM_014904 /// XM_005269629 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from mutant phenotype /// 0035773 // insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203884_s_at NM_014904 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014904.1 /DEF=Homo sapiens KIAA0941 protein (KIAA0941), mRNA. /FEA=mRNA /GEN=KIAA0941 /PROD=KIAA0941 protein /DB_XREF=gi:7662393 /UG=Hs.173656 KIAA0941 protein /FL=gb:AB023158.1 gb:NM_014904.1" NM_014904 RAB11 family interacting protein 2 (class I) RAB11FIP2 22841 NM_014904 /// XM_005269629 0006810 // transport // inferred from electronic annotation /// 0006833 // water transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from mutant phenotype /// 0035773 // insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction 203885_at NM_014999 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014999.1 /DEF=Homo sapiens KIAA0118 protein (KIAA0118), mRNA. /FEA=mRNA /GEN=KIAA0118 /PROD=KIAA0118 protein /DB_XREF=gi:7661921 /UG=Hs.184627 KIAA0118 protein /FL=gb:AF091035.1 gb:NM_014999.1" NM_014999 "RAB21, member RAS oncogene family" RAB21 23011 NM_014999 0006184 // GTP catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0019003 // GDP binding // inferred from direct assay 203886_s_at NM_001998 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001998.1 /DEF=Homo sapiens fibulin 2 (FBLN2), mRNA. /FEA=mRNA /GEN=FBLN2 /PROD=fibulin 2 precursor /DB_XREF=gi:4503664 /UG=Hs.198862 fibulin 2 /FL=gb:NM_001998.1" NM_001998 fibulin 2 FBLN2 2199 NM_001004019 /// NM_001165035 /// NM_001998 /// XM_006713026 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation 203887_s_at NM_000361 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000361.1 /DEF=Homo sapiens thrombomodulin (THBD), mRNA. /FEA=mRNA /GEN=THBD /PROD=thrombomodulin /DB_XREF=gi:4507482 /UG=Hs.2030 thrombomodulin /FL=gb:M16552.1 gb:NM_000361.1" NM_000361 thrombomodulin THBD 7056 NM_000361 0007165 // signal transduction // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // traceable author statement /// 0030195 // negative regulation of blood coagulation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051918 // negative regulation of fibrinolysis // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 203888_at NM_000361 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000361.1 /DEF=Homo sapiens thrombomodulin (THBD), mRNA. /FEA=mRNA /GEN=THBD /PROD=thrombomodulin /DB_XREF=gi:4507482 /UG=Hs.2030 thrombomodulin /FL=gb:M16552.1 gb:NM_000361.1" NM_000361 thrombomodulin THBD 7056 NM_000361 0007165 // signal transduction // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // traceable author statement /// 0030195 // negative regulation of blood coagulation // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051918 // negative regulation of fibrinolysis // traceable author statement 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation 203889_at NM_003020 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003020.1 /DEF=Homo sapiens secretory granule, neuroendocrine protein 1 (7B2 protein) (SGNE1), mRNA. /FEA=mRNA /GEN=SGNE1 /PROD=secretory granule, neuroendocrine protein 1 (7B2protein) /DB_XREF=gi:4506916 /UG=Hs.2265 secretory granule, neuroendocrine protein 1 (7B2 protein) /FL=gb:BC005349.1 gb:NM_003020.1" NM_003020 secretogranin V (7B2 protein) SCG5 6447 NM_001144757 /// NM_003020 /// XM_005254595 /// XM_005254596 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0046883 // regulation of hormone secretion // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity 0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from direct assay 203890_s_at BF686824 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF686824 /FEA=EST /DB_XREF=gi:11972232 /DB_XREF=est:602140792F1 /CLONE=IMAGE:4301998 /UG=Hs.25619 death-associated protein kinase 3 /FL=gb:AB007144.1 gb:NM_001348.1 gb:AB022341.1 BF686824 death-associated protein kinase 3 /// microRNA 637 DAPK3 /// MIR637 1613 /// 693222 NM_001348 /// NR_030367 /// XM_005259508 /// XM_005259509 "0000910 // cytokinesis // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 2000145 // regulation of cell motility // traceable author statement /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation" "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction" 203891_s_at NM_001348 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001348.1 /DEF=Homo sapiens death-associated protein kinase 3 (DAPK3), mRNA. /FEA=mRNA /GEN=DAPK3 /PROD=death-associated protein kinase 3 /DB_XREF=gi:4557510 /UG=Hs.25619 death-associated protein kinase 3 /FL=gb:AB007144.1 gb:NM_001348.1 gb:AB022341.1" NM_001348 death-associated protein kinase 3 /// microRNA 637 DAPK3 /// MIR637 1613 /// 693222 NM_001348 /// NR_030367 /// XM_005259508 /// XM_005259509 "0000910 // cytokinesis // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from direct assay /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // traceable author statement /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation /// 2000145 // regulation of cell motility // traceable author statement /// 2000249 // regulation of actin cytoskeleton reorganization // traceable author statement /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation" "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation" "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004683 // calmodulin-dependent protein kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction" 203892_at NM_006103 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006103.1 /DEF=Homo sapiens epididymis-specific, whey-acidic protein type, four-disulfide core; putative ovarian carcinoma marker (HE4), mRNA. /FEA=mRNA /GEN=HE4 /PROD=epididymis-specific, whey-acidic protein type,four-disulfide core; putative ovarian carcinoma marker /DB_XREF=gi:5174454 /UG=Hs.2719 epididymis-specific, whey-acidic protein type, four-disulfide core; putative ovarian carcinoma marker /FL=gb:NM_006103.1" NM_006103 WAP four-disulfide core domain 2 WFDC2 10406 NM_006103 /// NM_080733 /// NM_080734 /// NM_080735 /// NM_080736 0006508 // proteolysis // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0019828 // aspartic-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation 203893_at NM_016283 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016283.1 /DEF=Homo sapiens adrenal gland protein AD-004 (LOC51578), mRNA. /FEA=mRNA /GEN=LOC51578 /PROD=adrenal gland protein AD-004 /DB_XREF=gi:7706211 /UG=Hs.279586 adrenal gland protein AD-004 /FL=gb:AF151895.1 gb:AF110777.1 gb:NM_016283.1" NM_016283 adenylate kinase 6 AK6 102157402 NM_001015891 /// NM_016283 "0006200 // ATP catabolic process // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred by curator /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from mutant phenotype /// 0032435 // negative regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0060760 // positive regulation of response to cytokine stimulus // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred by curator" 0000125 // PCAF complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030914 // STAGA complex // inferred from direct assay /// 0033276 // transcription factor TFTC complex // inferred from direct assay /// 0070761 // pre-snoRNP complex // inferred from direct assay /// 0071339 // MLL1 complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from mutant phenotype /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070742 // C2H2 zinc finger domain binding // inferred from physical interaction 203894_at NM_016437 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016437.1 /DEF=Homo sapiens tubulin, gamma 2 (TUBG2), mRNA. /FEA=mRNA /GEN=TUBG2 /PROD=tubulin, gamma 2 /DB_XREF=gi:7706750 /UG=Hs.279669 tubulin, gamma 2 /FL=gb:AF225971.1 gb:NM_016437.1" NM_016437 "tubulin, gamma 2" TUBG2 27175 NM_016437 /// XM_005257222 /// XM_005257223 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007020 // microtubule nucleation // inferred from electronic annotation /// 0031122 // cytoplasmic microtubule organization // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0000930 // gamma-tubulin complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 203895_at AL535113 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL535113 /FEA=EST /DB_XREF=gi:12798606 /DB_XREF=est:AL535113 /CLONE=CS0DF008YC23 (3 prime) /UG=Hs.283006 phospholipase C, beta 4 /FL=gb:NM_000933.1 gb:L41349.1" AL535113 "phospholipase C, beta 4" PLCB4 5332 NM_000933 /// NM_001172646 /// NM_182797 /// XM_005260724 /// XM_005260728 /// XM_006723568 /// XM_006723569 /// XM_006723570 /// XM_006723571 /// XM_006723572 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203896_s_at NM_000933 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000933.1 /DEF=Homo sapiens phospholipase C, beta 4 (PLCB4), mRNA. /FEA=mRNA /GEN=PLCB4 /PROD=phospholipase C, beta 4 /DB_XREF=gi:4505866 /UG=Hs.283006 phospholipase C, beta 4 /FL=gb:NM_000933.1 gb:L41349.1" NM_000933 "phospholipase C, beta 4" PLCB4 5332 NM_000933 /// NM_001172646 /// NM_182797 /// XM_005260724 /// XM_005260728 /// XM_006723568 /// XM_006723569 /// XM_006723570 /// XM_006723571 /// XM_006723572 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 203897_at BE963444 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE963444 /FEA=EST /DB_XREF=gi:11766863 /DB_XREF=est:601657224R1 /CLONE=IMAGE:3866357 /UG=Hs.28607 hypothetical protein A-211C6.1 /FL=gb:NM_020424.1 BE963444 LYR motif containing 1 LYRM1 57149 NM_001128301 /// NM_001128302 /// NM_020424 /// XM_005255444 /// XM_005255445 /// XM_006721070 0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 203898_at AU154853 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU154853 /FEA=EST /DB_XREF=gi:11016374 /DB_XREF=est:AU154853 /CLONE=OVARC1000240 /UG=Hs.300684 calcitonin gene-related peptide-receptor component protein /FL=gb:BC000783.1 gb:AF073792.1 gb:U51134.1 gb:NM_014478.1 AU154853 CGRP receptor component CRCP 27297 NM_001040647 /// NM_001040648 /// NM_001142414 /// NM_014478 /// NR_024548 "0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007340 // acrosome reaction // non-traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation" 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009360 // DNA polymerase III complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001635 // calcitonin gene-related polypeptide receptor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0004948 // calcitonin receptor activity // non-traceable author statement 203899_s_at NM_014478 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014478.1 /DEF=Homo sapiens calcitonin gene-related peptide-receptor component protein (CGRP-RCP), mRNA. /FEA=mRNA /GEN=CGRP-RCP /PROD=calcitonin gene-related peptide-receptorcomponent protein /DB_XREF=gi:7656976 /UG=Hs.300684 calcitonin gene-related peptide-receptor component protein /FL=gb:BC000783.1 gb:AF073792.1 gb:U51134.1 gb:NM_014478.1" NM_014478 CGRP receptor component CRCP 27297 NM_001040647 /// NM_001040648 /// NM_001142414 /// NM_014478 /// NR_024548 "0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007340 // acrosome reaction // non-traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation" 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009360 // DNA polymerase III complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0001635 // calcitonin gene-related polypeptide receptor activity // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from direct assay /// 0004948 // calcitonin receptor activity // non-traceable author statement 203900_at NM_024547 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024547.1 /DEF=Homo sapiens KIAA0467 protein (KIAA0467), mRNA. /FEA=mRNA /GEN=KIAA0467 /PROD=hypothetical protein FLJ23425 /DB_XREF=gi:13386459 /UG=Hs.301943 KIAA0467 protein /FL=gb:NM_024547.1" NM_024547 seizure threshold 2 homolog (mouse) SZT2 23334 NM_001012960 /// NM_001012961 /// NM_015284 /// NM_182518 /// XM_005270686 /// XM_006710501 /// XM_006710502 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from electronic annotation /// 1901668 // regulation of superoxide dismutase activity // inferred from sequence or structural similarity 0005777 // peroxisome // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 203901_at NM_006116 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006116.1 /DEF=Homo sapiens transforming growth factor beta-activated kinase-binding protein 1 (TAB1), mRNA. /FEA=mRNA /GEN=TAB1 /PROD=transforming growth factor beta-activatedkinase-binding protein 1 /DB_XREF=gi:5174702 /UG=Hs.31472 transforming growth factor beta-activated kinase-binding protein 1 /FL=gb:U49928.1 gb:NM_006116.1" NM_006116 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TAB1 10454 NM_006116 /// NM_153497 "0000185 // activation of MAPKKK activity // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007249 // I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019209 // kinase activator activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0048273 // mitogen-activated protein kinase p38 binding // inferred from electronic annotation 203902_at AU148222 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU148222 /FEA=EST /DB_XREF=gi:11009743 /DB_XREF=est:AU148222 /CLONE=MAMMA1002938 /UG=Hs.31720 hephaestin /FL=gb:AB014598.1 gb:NM_014799.1 AU148222 hephaestin HEPH 9843 NM_001130860 /// NM_001282141 /// NM_014799 /// NM_138737 /// XM_006724719 /// XM_006724720 /// XM_006724721 /// XM_006724722 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004322 // ferroxidase activity // inferred from mutant phenotype /// 0005507 // copper ion binding // inferred from mutant phenotype /// 0008198 // ferrous iron binding // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203903_s_at NM_014799 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014799.1 /DEF=Homo sapiens hephaestin (HEPH), mRNA. /FEA=mRNA /GEN=HEPH /PROD=hephaestin /DB_XREF=gi:7662253 /UG=Hs.31720 hephaestin /FL=gb:AB014598.1 gb:NM_014799.1" NM_014799 hephaestin HEPH 9843 NM_001130860 /// NM_001282141 /// NM_014799 /// NM_138737 /// XM_006724719 /// XM_006724720 /// XM_006724721 /// XM_006724722 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from mutant phenotype /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0004322 // ferroxidase activity // inferred from mutant phenotype /// 0005507 // copper ion binding // inferred from mutant phenotype /// 0008198 // ferrous iron binding // inferred from mutant phenotype /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203904_x_at NM_002231 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002231.2 /DEF=Homo sapiens kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) (KAI1), mRNA. /FEA=mRNA /GEN=KAI1 /PROD=kangai 1 /DB_XREF=gi:13259537 /UG=Hs.323949 kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) /FL=gb:BC000726.1 gb:BC001821.1 gb:NM_002231.2 gb:U20770.1" NM_002231 CD82 molecule CD82 3732 NM_001024844 /// NM_002231 /// XM_006718222 /// XM_006718223 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 203905_at NM_002582 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002582.1 /DEF=Homo sapiens poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), mRNA. /FEA=mRNA /GEN=PARN /PROD=poly(A)-specific ribonuclease (deadenylationnuclease) /DB_XREF=gi:4505610 /UG=Hs.43445 poly(A)-specific ribonuclease (deadenylation nuclease) /FL=gb:NM_002582.1" NM_002582 poly(A)-specific ribonuclease PARN 5073 NM_001134477 /// NM_001242992 /// NM_002582 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // traceable author statement /// 0006402 // mRNA catabolic process // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0009451 // RNA modification // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0090305 // nucleic acid phosphodiester bond hydrolysis // traceable author statement /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // inferred from electronic annotation /// 0090503 // RNA phosphodiester bond hydrolysis, exonucleolytic // traceable author statement" 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // traceable author statement /// 0004518 // nuclease activity // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0004535 // poly(A)-specific ribonuclease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203906_at AI652645 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI652645 /FEA=EST /DB_XREF=gi:4736624 /DB_XREF=est:wb30b07.x1 /CLONE=IMAGE:2307157 /UG=Hs.4764 KIAA0763 gene product /FL=gb:AB018306.1 gb:NM_014869.1 AI652645 IQ motif and Sec7 domain 1 IQSEC1 9922 NM_001134382 /// NM_014869 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203907_s_at NM_014869 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014869.1 /DEF=Homo sapiens KIAA0763 gene product (KIAA0763), mRNA. /FEA=mRNA /GEN=KIAA0763 /PROD=KIAA0763 gene product /DB_XREF=gi:7662289 /UG=Hs.4764 KIAA0763 gene product /FL=gb:AB018306.1 gb:NM_014869.1" NM_014869 IQ motif and Sec7 domain 1 IQSEC1 9922 NM_001134382 /// NM_014869 0016192 // vesicle-mediated transport // not recorded /// 0030036 // actin cytoskeleton organization // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 203908_at NM_003759 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003759.1 /DEF=Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4), mRNA. /FEA=mRNA /GEN=SLC4A4 /PROD=solute carrier family 4, sodium bicarbonatecotransporter, member 4 /DB_XREF=gi:4507024 /UG=Hs.5462 solute carrier family 4, sodium bicarbonate cotransporter, member 4 /FL=gb:AF007216.1 gb:NM_003759.1" NM_003759 "solute carrier family 4 (sodium bicarbonate cotransporter), member 4" SLC4A4 8671 NM_001098484 /// NM_001134742 /// NM_003759 /// XM_005265704 /// XM_006714398 /// XM_006714399 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation 203909_at NM_006359 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006359.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 6 (SLC9A6), mRNA. /FEA=mRNA /GEN=SLC9A6 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 6 /DB_XREF=gi:5454069 /UG=Hs.62185 solute carrier family 9 (sodiumhydrogen exchanger), isoform 6 /FL=gb:AF030409.1 gb:NM_006359.1" NM_006359 "solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6" SLC9A6 10479 NM_001042537 /// NM_001177651 /// NM_006359 /// XM_006724726 0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006812 // cation transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // inferred from electronic annotation /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0048675 // axon extension // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0097484 // dendrite extension // inferred from direct assay /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0031901 // early endosome membrane // traceable author statement /// 0055038 // recycling endosome membrane // inferred from direct assay 0015297 // antiporter activity // inferred from electronic annotation /// 0015299 // solute:proton antiporter activity // inferred from electronic annotation /// 0015385 // sodium:proton antiporter activity // inferred from electronic annotation 203910_at NM_004815 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004815.1 /DEF=Homo sapiens PTPL1-associated RhoGAP 1 (PARG1), mRNA. /FEA=mRNA /GEN=PARG1 /PROD=PTPL1-associated RhoGAP 1 /DB_XREF=gi:4758881 /UG=Hs.70983 PTPL1-associated RhoGAP 1 /FL=gb:U90920.1 gb:NM_004815.1" NM_004815 Rho GTPase activating protein 29 ARHGAP29 9411 NM_004815 /// XM_006711048 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203911_at NM_002885 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002885.1 /DEF=Homo sapiens RAP1, GTPase activating protein 1 (RAP1GA1), mRNA. /FEA=mRNA /GEN=RAP1GA1 /PROD=RAP1, GTPase activating protein 1 /DB_XREF=gi:4506414 /UG=Hs.75151 RAP1, GTPase activating protein 1 /FL=gb:M64788.1 gb:NM_002885.1" NM_002885 RAP1 GTPase activating protein RAP1GAP 5909 NM_001145657 /// NM_001145658 /// NM_002885 /// XM_005245954 /// XM_005245955 /// XM_005245956 /// XM_006710804 /// XM_006710805 /// XM_006710806 /// XM_006710807 0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0032318 // regulation of Ras GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay 0003924 // GTPase activity // non-traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from physical interaction /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046582 // Rap GTPase activator activity // inferred from direct assay 203912_s_at NM_006730 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006730.1 /DEF=Homo sapiens deoxyribonuclease I-like 1 (DNASE1L1), mRNA. /FEA=mRNA /GEN=DNASE1L1 /PROD=deoxyribonuclease I-like 1 /DB_XREF=gi:5803006 /UG=Hs.77091 deoxyribonuclease I-like 1 /FL=gb:U06846.1 gb:NM_006730.1" NM_006730 deoxyribonuclease I-like 1 DNASE1L1 1774 NM_001009932 /// NM_001009933 /// NM_001009934 /// NM_006730 /// XM_005277829 "0000737 // DNA catabolic process, endonucleolytic // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006308 // DNA catabolic process // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation" 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003677 // DNA binding // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004536 // deoxyribonuclease activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016888 // endodeoxyribonuclease activity, producing 5'-phosphomonoesters // inferred from electronic annotation" 203913_s_at AL574184 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL574184 /FEA=EST /DB_XREF=gi:12934146 /DB_XREF=est:AL574184 /CLONE=CS0DI039YJ22 (3 prime) /UG=Hs.77348 hydroxyprostaglandin dehydrogenase 15-(NAD) /FL=gb:L76465.1 gb:NM_000860.1 AL574184 hydroxyprostaglandin dehydrogenase 15-(NAD) HPGD 3248 NM_000860 /// NM_001145816 /// NM_001256301 /// NM_001256305 /// NM_001256306 /// NM_001256307 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030728 // ovulation // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070493 // thrombin receptor signaling pathway // inferred from sequence or structural similarity /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from direct assay /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay 203914_x_at NM_000860 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000860.1 /DEF=Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), mRNA. /FEA=mRNA /GEN=HPGD /PROD=hydroxyprostaglandin dehydrogenase 15-(NAD) /DB_XREF=gi:4504478 /UG=Hs.77348 hydroxyprostaglandin dehydrogenase 15-(NAD) /FL=gb:L76465.1 gb:NM_000860.1" NM_000860 hydroxyprostaglandin dehydrogenase 15-(NAD) HPGD 3248 NM_000860 /// NM_001145816 /// NM_001256301 /// NM_001256305 /// NM_001256306 /// NM_001256307 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007565 // female pregnancy // inferred from direct assay /// 0007567 // parturition // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019371 // cyclooxygenase pathway // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030728 // ovulation // inferred from sequence or structural similarity /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070493 // thrombin receptor signaling pathway // inferred from sequence or structural similarity /// 0097070 // ductus arteriosus closure // inferred from sequence or structural similarity /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from direct assay /// 0004957 // prostaglandin E receptor activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // inferred from direct assay /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // non-traceable author statement /// 0016404 // 15-hydroxyprostaglandin dehydrogenase (NAD+) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0050662 // coenzyme binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay /// 0070403 // NAD+ binding // inferred from direct assay 203915_at NM_002416 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002416.1 /DEF=Homo sapiens monokine induced by gamma interferon (MIG), mRNA. /FEA=mRNA /GEN=MIG /PROD=monokine induced by gamma interferon /DB_XREF=gi:4505186 /UG=Hs.77367 monokine induced by gamma interferon /FL=gb:NM_002416.1" NM_002416 chemokine (C-X-C motif) ligand 9 CXCL9 4283 NM_002416 0006935 // chemotaxis // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0030816 // positive regulation of cAMP metabolic process // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0043950 // positive regulation of cAMP-mediated signaling // inferred from direct assay /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation 0005125 // cytokine activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from direct assay /// 0048248 // CXCR3 chemokine receptor binding // inferred from direct assay 203916_at NM_003635 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003635.1 /DEF=Homo sapiens N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 2 (NDST2), mRNA. /FEA=mRNA /GEN=NDST2 /PROD=N-deacetylaseN-sulfotransferase (heparanglucosaminyl) 2 /DB_XREF=gi:4505352 /UG=Hs.78473 N-deacetylaseN-sulfotransferase (heparan glucosaminyl) 2 /FL=gb:U36601.1 gb:NM_003635.1" NM_003635 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 NDST2 8509 NM_003635 /// XM_005270255 /// XM_005270256 /// XM_006718046 0002002 // regulation of angiotensin levels in blood // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0015012 // heparan sulfate proteoglycan biosynthetic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030210 // heparin biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0015016 // [heparan sulfate]-glucosamine N-sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019213 // deacetylase activity // inferred from electronic annotation 203917_at NM_001338 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001338.1 /DEF=Homo sapiens coxsackie virus and adenovirus receptor (CXADR), mRNA. /FEA=mRNA /GEN=CXADR /PROD=coxsackie virus and adenovirus receptor /DB_XREF=gi:4503172 /UG=Hs.79187 coxsackie virus and adenovirus receptor /FL=gb:BC003684.1 gb:U90716.1 gb:NM_001338.1" NM_001338 coxsackie virus and adenovirus receptor CXADR 1525 NM_001207063 /// NM_001207064 /// NM_001207065 /// NM_001207066 /// NM_001338 0007005 // mitochondrion organization // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from direct assay /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008354 // germ cell migration // inferred from sequence or structural similarity /// 0009615 // response to virus // inferred from electronic annotation /// 0010669 // epithelial structure maintenance // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034109 // homotypic cell-cell adhesion // inferred from direct assay /// 0045216 // cell-cell junction organization // inferred from sequence or structural similarity /// 0046629 // gamma-delta T cell activation // inferred from sequence or structural similarity /// 0048739 // cardiac muscle fiber development // inferred from sequence or structural similarity /// 0050776 // regulation of immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0060044 // negative regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0070633 // transepithelial transport // inferred from mutant phenotype /// 0086067 // AV node cell to bundle of His cell communication // inferred from sequence or structural similarity 0001669 // acrosomal vesicle // inferred from sequence or structural similarity /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0014704 // intercalated disc // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016327 // apicolateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay /// 0044297 // cell body // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from direct assay 0001618 // virus receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0050839 // cell adhesion molecule binding // inferred from physical interaction /// 0071253 // connexin binding // inferred from sequence or structural similarity 203918_at NM_002587 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002587.1 /DEF=Homo sapiens protocadherin 1 (cadherin-like 1) (PCDH1), mRNA. /FEA=mRNA /GEN=PCDH1 /PROD=protocadherin 1 (cadherin-like 1) /DB_XREF=gi:4505630 /UG=Hs.79769 protocadherin 1 (cadherin-like 1) /FL=gb:L11370.1 gb:NM_002587.1" NM_002587 protocadherin 1 PCDH1 5097 NM_001278613 /// NM_001278615 /// NM_002587 /// NM_032420 /// XM_005268452 /// XM_005268453 /// XM_005268454 /// XM_005268455 /// XM_005268456 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005911 // cell-cell junction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 203919_at NM_003195 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003195.1 /DEF=Homo sapiens transcription elongation factor A (SII), 2 (TCEA2), mRNA. /FEA=mRNA /GEN=TCEA2 /PROD=transcription elongation factor A (SII), 2 /DB_XREF=gi:4507384 /UG=Hs.80598 transcription elongation factor A (SII), 2 /FL=gb:D50495.1 gb:NM_003195.1" NM_003195 "transcription elongation factor A (SII), 2" TCEA2 6919 NM_003195 /// NM_198723 /// XM_005260229 /// XM_006723873 /// XM_006723874 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006354 // DNA-templated transcription, elongation // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0008023 // transcription elongation factor complex // non-traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203920_at NM_005693 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005693.1 /DEF=Homo sapiens nuclear receptor subfamily 1, group H, member 3 (NR1H3), mRNA. /FEA=mRNA /GEN=NR1H3 /PROD=nuclear receptor subfamily 1, group H, member 3 /DB_XREF=gi:5031892 /UG=Hs.81336 nuclear receptor subfamily 1, group H, member 3 /FL=gb:NM_005693.1 gb:U22662.1" NM_005693 "nuclear receptor subfamily 1, group H, member 3" NR1H3 10062 NM_001130101 /// NM_001130102 /// NM_001251934 /// NM_001251935 /// NM_005693 /// XM_005252705 /// XM_005252706 /// XM_005252707 /// XM_005252709 /// XM_005252710 /// XM_005252713 /// XM_005252715 /// XM_005252716 /// XM_005252718 /// XM_006718112 /// XM_006718113 /// XM_006718114 /// XM_006718115 /// XM_006718116 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from mutant phenotype /// 0010870 // positive regulation of receptor biosynthetic process // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from mutant phenotype /// 0010887 // negative regulation of cholesterol storage // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0032376 // positive regulation of cholesterol transport // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // traceable author statement /// 0043031 // negative regulation of macrophage activation // inferred from sequence or structural similarity /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048550 // negative regulation of pinocytosis // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity /// 0055092 // sterol homeostasis // inferred from sequence or structural similarity /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // non-traceable author statement /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0090188 // negative regulation of pancreatic juice secretion // inferred from sequence or structural similarity /// 0090341 // negative regulation of secretion of lysosomal enzymes // inferred from sequence or structural similarity /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015485 // cholesterol binding // traceable author statement /// 0032810 // sterol response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203921_at NM_004267 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004267.1 /DEF=Homo sapiens carbohydrate (chondroitin 6keratan) sulfotransferase 2 (CHST2), mRNA. /FEA=mRNA /GEN=CHST2 /PROD=carbohydrate (chondroitin 6keratan)sulfotransferase 2 /DB_XREF=gi:4757983 /UG=Hs.8786 carbohydrate (chondroitin 6keratan) sulfotransferase 2 /FL=gb:AB021124.1 gb:AB014679.1 gb:AB014680.1 gb:AF083066.1 gb:NM_004267.1" NM_004267 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 CHST2 9435 NM_004267 0005975 // carbohydrate metabolic process // traceable author statement /// 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031228 // intrinsic component of Golgi membrane // non-traceable author statement 0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 203922_s_at AI308863 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI308863 /FEA=EST /DB_XREF=gi:4003734 /DB_XREF=est:qo78d02.x1 /CLONE=IMAGE:1914627 /UG=Hs.88974 cytochrome b-245, beta polypeptide (chronic granulomatous disease) /FL=gb:NM_000397.2" AI308863 "cytochrome b-245, beta polypeptide" CYBB 1536 NM_000397 "0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007584 // response to nutrient // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0090382 // phagosome maturation // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from mutant phenotype 203923_s_at NM_000397 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000397.2 /DEF=Homo sapiens cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB), mRNA. /FEA=mRNA /GEN=CYBB /PROD=cytochrome b-245, beta polypeptide (chronicgranulomatous disease) /DB_XREF=gi:6996020 /UG=Hs.88974 cytochrome b-245, beta polypeptide (chronic granulomatous disease) /FL=gb:NM_000397.2" NM_000397 "cytochrome b-245, beta polypeptide" CYBB 1536 NM_000397 "0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006801 // superoxide metabolic process // inferred from direct assay /// 0006801 // superoxide metabolic process // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007584 // response to nutrient // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from direct assay /// 0042554 // superoxide anion generation // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // inferred from mutant phenotype /// 0045730 // respiratory burst // traceable author statement /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0051701 // interaction with host // traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0055114 // oxidation-reduction process // traceable author statement /// 0090382 // phagosome maturation // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0043020 // NADPH oxidase complex // inferred from direct assay /// 0043020 // NADPH oxidase complex // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from direct assay /// 0016175 // superoxide-generating NADPH oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from mutant phenotype /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050660 // flavin adenine dinucleotide binding // inferred from mutant phenotype 203924_at NM_000846 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000846.1 /DEF=Homo sapiens glutathione S-transferase A2 (GSTA2), mRNA. /FEA=mRNA /GEN=GSTA2 /PROD=glutathione S-transferase A2 /DB_XREF=gi:4504170 /UG=Hs.89552 glutathione S-transferase A2 /FL=gb:BC002895.1 gb:M15872.1 gb:M21758.1 gb:M16594.1 gb:M14777.1 gb:M25627.1 gb:NM_000846.1" NM_000846 glutathione S-transferase alpha 1 GSTA1 2938 NM_145740 /// XM_005249034 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred by curator /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004364 // glutathione transferase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 203925_at NM_002061 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002061.1 /DEF=Homo sapiens glutamate-cysteine ligase, modifier subunit (GCLM), mRNA. /FEA=mRNA /GEN=GCLM /PROD=glutamate-cysteine ligase regulatory protein /DB_XREF=gi:4504010 /UG=Hs.89709 glutamate-cysteine ligase, modifier subunit /FL=gb:NM_002061.1 gb:L35546.1" NM_002061 "glutamate-cysteine ligase, modifier subunit" GCLM 2730 NM_002061 /// XM_005270754 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0006534 // cysteine metabolic process // inferred from electronic annotation /// 0006536 // glutamate metabolic process // inferred from direct assay /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035229 // positive regulation of glutamate-cysteine ligase activity // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050880 // regulation of blood vessel size // inferred from mutant phenotype /// 0051409 // response to nitrosative stress // inferred from electronic annotation /// 0051900 // regulation of mitochondrial depolarization // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0017109 // glutamate-cysteine ligase complex // inferred from electronic annotation 0004357 // glutamate-cysteine ligase activity // inferred from direct assay /// 0004357 // glutamate-cysteine ligase activity // inferred from mutant phenotype /// 0016874 // ligase activity // inferred from electronic annotation /// 0035226 // glutamate-cysteine ligase catalytic subunit binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 203926_x_at NM_001687 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001687.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit (ATP5D), mRNA. /FEA=mRNA /GEN=ATP5D /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, delta subunit /DB_XREF=gi:4502296 /UG=Hs.89761 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit /FL=gb:BC002389.1 gb:BC004426.1 gb:NM_001687.1" NM_001687 "ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit" ATP5D 513 NM_001001975 /// NM_001687 0006119 // oxidative phosphorylation // non-traceable author statement /// 0006200 // ATP catabolic process // non-traceable author statement /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred by curator /// 0042776 // mitochondrial ATP synthesis coupled proton transport // non-traceable author statement /// 0042776 // mitochondrial ATP synthesis coupled proton transport // traceable author statement /// 0044237 // cellular metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046688 // response to copper ion // non-traceable author statement "0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) // non-traceable author statement /// 0005739 // mitochondrion // non-traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation" "0005215 // transporter activity // non-traceable author statement /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from direct assay /// 0022857 // transmembrane transporter activity // inferred by curator /// 0043531 // ADP binding // non-traceable author statement /// 0046933 // proton-transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation" 203927_at NM_004556 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004556.1 /DEF=Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (NFKBIE), mRNA. /FEA=mRNA /GEN=NFKBIE /PROD=nuclear factor of kappa light polypeptide geneenhancer in B-cells inhibitor, epsilon /DB_XREF=gi:4758805 /UG=Hs.91640 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon /FL=gb:U91616.1 gb:NM_004556.1" NM_004556 "nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon" NFKBIE 4794 NM_004556 0042942 // D-serine transport // inferred from electronic annotation /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 203928_x_at AI870749 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI870749 /FEA=EST /DB_XREF=gi:5544717 /DB_XREF=est:wl76d10.x1 /CLONE=IMAGE:2430835 /UG=Hs.101174 microtubule-associated protein tau /FL=gb:NM_016835.1 AI870749 microtubule-associated protein tau MAPT 4137 NM_001123066 /// NM_001123067 /// NM_001203251 /// NM_001203252 /// NM_005910 /// NM_016834 /// NM_016835 /// NM_016841 /// XM_005257362 /// XM_005257364 /// XM_005257365 /// XM_005257366 /// XM_005257367 /// XM_005257368 /// XM_005257369 /// XM_005257370 /// XM_005257371 /// XM_005257372 /// XM_005275647 /// XM_005275648 /// XM_006725265 /// XM_006725266 /// XM_006725267 /// XM_006725268 /// XM_006725269 /// XM_006725270 /// XM_006725271 /// XM_006725272 /// XM_006725273 /// XM_006725274 /// XM_006725275 /// XM_006725616 /// XM_006725617 /// XM_006725618 /// XM_006725619 /// XM_006725620 /// XM_006725621 /// XM_006725622 /// XM_006725623 /// XM_006725624 /// XM_006725625 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from genetic interaction /// 0031113 // regulation of microtubule polymerization // non-traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048699 // generation of neurons // non-traceable author statement /// 0060632 // regulation of microtubule-based movement // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045298 // tubulin complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from physical interaction 203929_s_at AI056359 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI056359 /FEA=EST /DB_XREF=gi:3330225 /DB_XREF=est:oy48b08.x1 /CLONE=IMAGE:1669047 /UG=Hs.101174 microtubule-associated protein tau /FL=gb:NM_016835.1 AI056359 microtubule-associated protein tau MAPT 4137 NM_001123066 /// NM_001123067 /// NM_001203251 /// NM_001203252 /// NM_005910 /// NM_016834 /// NM_016835 /// NM_016841 /// XM_005257362 /// XM_005257364 /// XM_005257365 /// XM_005257366 /// XM_005257367 /// XM_005257368 /// XM_005257369 /// XM_005257370 /// XM_005257371 /// XM_005257372 /// XM_005275647 /// XM_005275648 /// XM_006725265 /// XM_006725266 /// XM_006725267 /// XM_006725268 /// XM_006725269 /// XM_006725270 /// XM_006725271 /// XM_006725272 /// XM_006725273 /// XM_006725274 /// XM_006725275 /// XM_006725616 /// XM_006725617 /// XM_006725618 /// XM_006725619 /// XM_006725620 /// XM_006725621 /// XM_006725622 /// XM_006725623 /// XM_006725624 /// XM_006725625 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from genetic interaction /// 0031113 // regulation of microtubule polymerization // non-traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048699 // generation of neurons // non-traceable author statement /// 0060632 // regulation of microtubule-based movement // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045298 // tubulin complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from physical interaction 203930_s_at NM_016835 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016835.1 /DEF=Homo sapiens microtubule-associated protein tau (MAPT), transcript variant 1, mRNA. /FEA=mRNA /GEN=MAPT /PROD=microtubule-associated protein tau, isoform 1 /DB_XREF=gi:8400712 /UG=Hs.101174 microtubule-associated protein tau /FL=gb:NM_016835.1" NM_016835 microtubule-associated protein tau MAPT 4137 NM_001123066 /// NM_001123067 /// NM_001203251 /// NM_001203252 /// NM_005910 /// NM_016834 /// NM_016835 /// NM_016841 /// XM_005257362 /// XM_005257364 /// XM_005257365 /// XM_005257366 /// XM_005257367 /// XM_005257368 /// XM_005257369 /// XM_005257370 /// XM_005257371 /// XM_005257372 /// XM_005275647 /// XM_005275648 /// XM_006725265 /// XM_006725266 /// XM_006725267 /// XM_006725268 /// XM_006725269 /// XM_006725270 /// XM_006725271 /// XM_006725272 /// XM_006725273 /// XM_006725274 /// XM_006725275 /// XM_006725616 /// XM_006725617 /// XM_006725618 /// XM_006725619 /// XM_006725620 /// XM_006725621 /// XM_006725622 /// XM_006725623 /// XM_006725624 /// XM_006725625 0000226 // microtubule cytoskeleton organization // inferred from direct assay /// 0001764 // neuron migration // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from genetic interaction /// 0031113 // regulation of microtubule polymerization // non-traceable author statement /// 0031116 // positive regulation of microtubule polymerization // inferred from direct assay /// 0032387 // negative regulation of intracellular transport // inferred from electronic annotation /// 0045773 // positive regulation of axon extension // inferred from direct assay /// 0047497 // mitochondrion transport along microtubule // inferred from electronic annotation /// 0048675 // axon extension // inferred from electronic annotation /// 0048699 // generation of neurons // non-traceable author statement /// 0060632 // regulation of microtubule-based movement // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from direct assay /// 0030426 // growth cone // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045298 // tubulin complex // inferred from direct assay 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034185 // apolipoprotein binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from physical interaction 203931_s_at NM_002949 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002949.1 /DEF=Homo sapiens mitochondrial ribosomal protein L12 (MRPL12), mRNA. /FEA=mRNA /GEN=MRPL12 /PROD=mitochondrial ribosomal protein L12 /DB_XREF=gi:4506672 /UG=Hs.109059 mitochondrial ribosomal protein L12 /FL=gb:BC002344.1 gb:U25041.1 gb:AF105278.1 gb:NM_002949.1" NM_002949 mitochondrial ribosomal protein L12 MRPL12 6182 NM_002949 "0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006390 // transcription from mitochondrial promoter // inferred from direct assay /// 0006412 // translation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // traceable author statement /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005762 // mitochondrial large ribosomal subunit // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005310 // dicarboxylic acid transmembrane transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203932_at NM_002118 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002118.1 /DEF=Homo sapiens major histocompatibility complex, class II, DM beta (HLA-DMB), mRNA. /FEA=mRNA /GEN=HLA-DMB /PROD=major histocompatibility complex, class II, DMbeta /DB_XREF=gi:4504398 /UG=Hs.1162 major histocompatibility complex, class II, DM beta /FL=gb:NM_002118.1 gb:U15085.1" NM_002118 "major histocompatibility complex, class II, DM beta" HLA-DMB 3109 NM_002118 0002376 // immune system process // inferred from electronic annotation /// 0002399 // MHC class II protein complex assembly // inferred from mutant phenotype /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 2001190 // positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay 203933_at NM_014700 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014700.1 /DEF=Homo sapiens KIAA0665 gene product (KIAA0665), mRNA. /FEA=mRNA /GEN=KIAA0665 /PROD=KIAA0665 gene product /DB_XREF=gi:7662233 /UG=Hs.119004 KIAA0665 gene product /FL=gb:AB014565.1 gb:NM_014700.1" NM_014700 RAB11 family interacting protein 3 (class II) RAB11FIP3 9727 NM_001142272 /// NM_014700 /// XM_005255713 /// XM_005255714 /// XM_005255715 /// XM_005255717 /// XM_005255718 /// XM_006720987 /// XM_006720988 /// XM_006725242 /// XM_006725243 /// XM_006725244 /// XM_006725245 /// XM_006725246 /// XM_006725247 /// XM_006725248 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0032456 // endocytic recycling // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005825 // half bridge of spindle pole body // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay /// 0055037 // recycling endosome // inferred from direct assay /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // non-traceable author statement /// 0030306 // ADP-ribosylation factor binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203934_at NM_002253 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002253.1 /DEF=Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), mRNA. /FEA=mRNA /GEN=KDR /PROD=kinase insert domain receptor (a type IIIreceptor tyrosine kinase) /DB_XREF=gi:11321596 /UG=Hs.12337 kinase insert domain receptor (a type III receptor tyrosine kinase) /FL=gb:NM_002253.1 gb:AF035121.1 gb:AF063658.1" NM_002253 kinase insert domain receptor (a type III receptor tyrosine kinase) KDR 3791 NM_002253 0001525 // angiogenesis // traceable author statement /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001945 // lymph vessel development // inferred from electronic annotation /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from sequence or structural similarity /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0003158 // endothelium development // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from mutant phenotype /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from mutant phenotype /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from direct assay /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from sequence or structural similarity /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from direct assay /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043129 // surfactant homeostasis // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045446 // endothelial cell differentiation // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // inferred from direct assay /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from mutant phenotype /// 0051894 // positive regulation of focal adhesion assembly // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation /// 0097443 // sorting endosome // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004716 // receptor signaling protein tyrosine kinase activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0038085 // vascular endothelial growth factor binding // inferred from physical interaction /// 0051879 // Hsp90 protein binding // traceable author statement" 203935_at NM_001105 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001105.2 /DEF=Homo sapiens activin A receptor, type I (ACVR1), mRNA. /FEA=mRNA /GEN=ACVR1 /PROD=activin A type I receptor precursor /DB_XREF=gi:10862690 /UG=Hs.150402 activin A receptor, type I /FL=gb:NM_001105.2 gb:L02911.1" NM_001105 "activin A receptor, type I" ACVR1 90 NM_001105 /// NM_001111067 /// XM_005246939 /// XM_005246940 /// XM_006712825 "0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001702 // gastrulation with mouth forming second // inferred from electronic annotation /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0002526 // acute inflammatory response // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from mutant phenotype /// 0003183 // mitral valve morphogenesis // inferred from mutant phenotype /// 0003289 // atrial septum primum morphogenesis // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007281 // germ cell development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0007498 // mesoderm development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009968 // negative regulation of signal transduction // inferred from mutant phenotype /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from mutant phenotype /// 0030501 // positive regulation of bone mineralization // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from mutant phenotype /// 0045669 // positive regulation of osteoblast differentiation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0051145 // smooth muscle cell differentiation // inferred from electronic annotation /// 0060037 // pharyngeal system development // inferred from electronic annotation /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060923 // cardiac muscle cell fate commitment // inferred from mutant phenotype /// 0061445 // endocardial cushion cell fate commitment // inferred from mutant phenotype /// 0071385 // cellular response to glucocorticoid stimulus // inferred from electronic annotation /// 2000017 // positive regulation of determination of dorsal identity // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype" 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048179 // activin receptor complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from reviewed computational analysis /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from electronic annotation /// 0005025 // transforming growth factor beta receptor activity, type I // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016361 // activin receptor activity, type I // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017046 // peptide hormone binding // non-traceable author statement /// 0019838 // growth factor binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048185 // activin binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from direct assay" 203936_s_at NM_004994 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004994.1 /DEF=Homo sapiens matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase) (MMP9), mRNA. /FEA=mRNA /GEN=MMP9 /PROD=matrix metalloproteinase 9 preproprotein /DB_XREF=gi:4826835 /UG=Hs.151738 matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase) /FL=gb:J05070.1 gb:NM_004994.1" NM_004994 "matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)" MMP9 4318 NM_004994 0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0007566 // embryo implantation // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030225 // macrophage differentiation // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation /// 0051549 // positive regulation of keratinocyte migration // inferred from mutant phenotype /// 1900122 // positive regulation of receptor binding // inferred from direct assay /// 2001258 // negative regulation of cation channel activity // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203937_s_at AW015313 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW015313 /FEA=EST /DB_XREF=gi:5864070 /DB_XREF=est:UI-H-BI0-aap-e-09-0-UI.s1 /CLONE=IMAGE:2710001 /UG=Hs.153022 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD /FL=gb:NM_005679.1 gb:L39059.1" AW015313 "TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa" TAF1C 9013 NM_001243156 /// NM_001243157 /// NM_001243158 /// NM_001243159 /// NM_001243160 /// NM_005679 /// NM_139353 /// XM_005256226 /// XM_005256227 /// XM_006721325 /// XM_006721326 /// XM_006721327 /// XM_006721328 /// XM_006721329 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203938_s_at NM_005679 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005679.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD (TAF1C), mRNA. /FEA=mRNA /GEN=TAF1C /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase I, C, 110kD /DB_XREF=gi:5032144 /UG=Hs.153022 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD /FL=gb:NM_005679.1 gb:L39059.1" NM_005679 "TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa" TAF1C 9013 NM_001243156 /// NM_001243157 /// NM_001243158 /// NM_001243159 /// NM_001243160 /// NM_005679 /// NM_139353 /// XM_005256226 /// XM_005256227 /// XM_006721325 /// XM_006721326 /// XM_006721327 /// XM_006721328 /// XM_006721329 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 203939_at NM_002526 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002526.1 /DEF=Homo sapiens 5 nucleotidase (CD73) (NT5), mRNA. /FEA=mRNA /GEN=NT5 /PROD=5 nucleotidase /DB_XREF=gi:4505466 /UG=Hs.153952 5 nucleotidase (CD73) /FL=gb:NM_002526.1" NM_002526 "5'-nucleotidase, ecto (CD73)" NT5E 4907 NM_001204813 /// NM_002526 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006195 // purine nucleotide catabolic process // traceable author statement /// 0006196 // AMP catabolic process // inferred from electronic annotation /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0009166 // nucleotide catabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046086 // adenosine biosynthetic process // inferred from electronic annotation /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0008253 // 5'-nucleotidase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203940_s_at NM_014909 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014909.1 /DEF=Homo sapiens KIAA1036 protein (KIAA1036), mRNA. /FEA=mRNA /GEN=KIAA1036 /PROD=KIAA1036 protein /DB_XREF=gi:7662453 /UG=Hs.155182 KIAA1036 protein /FL=gb:AB028959.1 gb:NM_014909.1" NM_014909 vasohibin 1 VASH1 22846 NM_014909 /// XM_006720080 0001525 // angiogenesis // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0009611 // response to wounding // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from genetic interaction /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from genetic interaction /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0045765 // regulation of angiogenesis // inferred from electronic annotation /// 1901491 // negative regulation of lymphangiogenesis // inferred from genetic interaction /// 2000772 // regulation of cellular senescence // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay 203941_at NM_018250 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018250.1 /DEF=Homo sapiens hypothetical protein FLJ10871 (FLJ10871), mRNA. /FEA=mRNA /GEN=FLJ10871 /PROD=hypothetical protein FLJ10871 /DB_XREF=gi:8922725 /UG=Hs.15562 hypothetical protein FLJ10871 /FL=gb:NM_018250.1" NM_018250 integrator complex subunit 9 INTS9 55756 NM_001145159 /// NM_001172562 /// NM_018250 /// NR_026826 /// XM_005273568 /// XM_006716356 /// XM_006716357 0016180 // snRNA processing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032039 // integrator complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 203942_s_at NM_017490 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017490.1 /DEF=Homo sapiens ELKL motif kinase (EMK1), transcript variant 1, mRNA. /FEA=mRNA /GEN=EMK1 /PROD=ELKL motif kinase 1 isoform a /DB_XREF=gi:9845486 /UG=Hs.157199 ELKL motif kinase /FL=gb:NM_017490.1" NM_017490 MAP/microtubule affinity-regulating kinase 2 MARK2 2011 NM_001039469 /// NM_001163296 /// NM_001163297 /// NM_004954 /// NM_017490 /// XM_006718441 /// XM_006718442 /// XM_006718443 /// XM_006718444 /// XM_006718445 /// XM_006718446 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from direct assay /// 0030010 // establishment of cell polarity // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from sequence or structural similarity /// 0050770 // regulation of axonogenesis // inferred from mutant phenotype /// 0051493 // regulation of cytoskeleton organization // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from mutant phenotype /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0045180 // basal cortex // inferred from electronic annotation /// 0097427 // microtubule bundle // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008289 // lipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from sequence or structural similarity" 203943_at NM_004798 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004798.1 /DEF=Homo sapiens kinesin family member 3B (KIF3B), mRNA. /FEA=mRNA /GEN=KIF3B /PROD=kinesin family member 3B /DB_XREF=gi:4758645 /UG=Hs.168212 kinesin family member 3B /FL=gb:AB002357.1 gb:NM_004798.1" NM_004798 kinesin family member 3B KIF3B 9371 NM_004798 0007018 // microtubule-based movement // traceable author statement /// 0007052 // mitotic spindle organization // traceable author statement /// 0007100 // mitotic centrosome separation // traceable author statement /// 0007368 // determination of left/right symmetry // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008089 // anterograde axon cargo transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0061024 // membrane organization // traceable author statement /// 0072383 // plus-end-directed vesicle transport along microtubule // traceable author statement /// 0090307 // spindle assembly involved in mitosis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // non-traceable author statement /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005873 // plus-end kinesin complex // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // non-traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016939 // kinesin II complex // inferred from direct assay /// 0030496 // midbody // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008574 // plus-end-directed microtubule motor activity // traceable author statement /// 0017048 // Rho GTPase binding // inferred from physical interaction 203944_x_at NM_007049 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007049.1 /DEF=Homo sapiens butyrophilin, subfamily 2, member A1 (BTN2A1), mRNA. /FEA=mRNA /GEN=BTN2A1 /PROD=butyrophilin, subfamily 2, member A1 /DB_XREF=gi:5921460 /UG=Hs.169963 butyrophilin, subfamily 2, member A1 /FL=gb:U90543.1 gb:NM_007049.1" NM_007049 "butyrophilin, subfamily 2, member A1" BTN2A1 11120 NM_001197233 /// NM_001197234 /// NM_007049 /// NM_078476 0006629 // lipid metabolic process // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation 203945_at NM_001172 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001172.2 /DEF=Homo sapiens arginase, type II (ARG2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ARG2 /PROD=arginase, type II precursor /DB_XREF=gi:10947110 /UG=Hs.172851 arginase, type II /FL=gb:NM_001172.2 gb:BC001350.1 gb:D86724.1 gb:U75667.1 gb:U82256.1" NM_001172 arginase 2 ARG2 384 NM_001172 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement "0004053 // arginase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203946_s_at U75667 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U75667.1 /DEF=Human arginase II mRNA, complete cds. /FEA=mRNA /PROD=arginase II /DB_XREF=gi:1763757 /UG=Hs.172851 arginase, type II /FL=gb:NM_001172.2 gb:BC001350.1 gb:D86724.1 gb:U75667.1 gb:U82256.1" U75667 arginase 2 ARG2 384 NM_001172 0000050 // urea cycle // inferred from electronic annotation /// 0000050 // urea cycle // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0006525 // arginine metabolic process // inferred from electronic annotation /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement "0004053 // arginase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 203947_at NM_001326 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001326.1 /DEF=Homo sapiens cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kD (CSTF3), mRNA. /FEA=mRNA /GEN=CSTF3 /PROD=cleavage stimulation factor subunit 3 /DB_XREF=gi:4557494 /UG=Hs.180034 cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kD /FL=gb:NM_001326.1 gb:U15782.1" NM_001326 "cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa" CSTF3 1479 NM_001033505 /// NM_001033506 /// NM_001326 /// XM_006718154 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006378 // mRNA polyadenylation // traceable author statement /// 0006379 // mRNA cleavage // traceable author statement /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay 203948_s_at J02694 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J02694.1 /DEF=Human myeloperoxidase mRNA, complete cds. /FEA=mRNA /GEN=MPO /PROD=myeloperoxidase /DB_XREF=gi:189039 /UG=Hs.1817 myeloperoxidase /FL=gb:M19507.1 gb:J02694.1 gb:NM_000250.1" J02694 myeloperoxidase MPO 4353 NM_000250 0001878 // response to yeast // inferred from electronic annotation /// 0002149 // hypochlorous acid biosynthetic process // inferred from electronic annotation /// 0002679 // respiratory burst involved in defense response // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0030141 // secretory granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0004601 // peroxidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203949_at NM_000250 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000250.1 /DEF=Homo sapiens myeloperoxidase (MPO), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MPO /PROD=myeloperoxidase /DB_XREF=gi:4557758 /UG=Hs.1817 myeloperoxidase /FL=gb:M19507.1 gb:J02694.1 gb:NM_000250.1" NM_000250 myeloperoxidase MPO 4353 NM_000250 0001878 // response to yeast // inferred from electronic annotation /// 0002149 // hypochlorous acid biosynthetic process // inferred from electronic annotation /// 0002679 // respiratory burst involved in defense response // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0050832 // defense response to fungus // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0030141 // secretory granule // inferred from direct assay /// 0042582 // azurophil granule // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0004601 // peroxidase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203950_s_at NM_001286 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001286.1 /DEF=Homo sapiens chloride channel 6 (CLCN6), transcript variant ClC-6a, mRNA. /FEA=mRNA /GEN=CLCN6 /PROD=chloride channel 6, isoform ClC-6a /DB_XREF=gi:4502872 /UG=Hs.211614 chloride channel 6 /FL=gb:NM_001286.1" NM_001286 "chloride channel, voltage-sensitive 6" CLCN6 1185 NM_001256959 /// NM_001286 /// NM_021735 /// NM_021736 /// NM_021737 /// NR_046428 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0006884 // cell volume homeostasis // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0015297 // antiporter activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation 203951_at NM_001299 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001299.1 /DEF=Homo sapiens calponin 1, basic, smooth muscle (CNN1), mRNA. /FEA=mRNA /GEN=CNN1 /PROD=calponin 1, basic, smooth muscle /DB_XREF=gi:4502920 /UG=Hs.21223 calponin 1, basic, smooth muscle /FL=gb:U37019.1 gb:D17408.1 gb:NM_001299.1" NM_001299 "calponin 1, basic, smooth muscle" CNN1 1264 NM_001299 /// XM_005259741 /// XM_006722648 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0031032 // actomyosin structure organization // inferred from electronic annotation 0005856 // cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 203952_at NM_007348 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007348.1 /DEF=Homo sapiens activating transcription factor 6 (ATF6), mRNA. /FEA=mRNA /GEN=ATF6 /PROD=activating transcription factor 6 /DB_XREF=gi:6671584 /UG=Hs.247433 activating transcription factor 6 /FL=gb:AF005887.1 gb:AB015856.1 gb:NM_007348.1" NM_007348 activating transcription factor 6 ATF6 22926 NM_007348 /// XM_006711224 /// XM_006711225 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006457 // protein folding // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006990 // positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0000139 // Golgi membrane // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203953_s_at BE791251 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE791251 /FEA=EST /DB_XREF=gi:10212449 /DB_XREF=est:601583966F1 /CLONE=IMAGE:3938249 /UG=Hs.25640 claudin 3 /FL=gb:AB000714.1 gb:NM_001306.1 BE791251 claudin 3 CLDN3 1365 NM_001306 0001666 // response to hypoxia // inferred from expression pattern /// 0007165 // signal transduction // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203954_x_at NM_001306 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001306.1 /DEF=Homo sapiens claudin 3 (CLDN3), mRNA. /FEA=mRNA /GEN=CLDN3 /PROD=claudin 3 /DB_XREF=gi:4502874 /UG=Hs.25640 claudin 3 /FL=gb:AB000714.1 gb:NM_001306.1" NM_001306 claudin 3 CLDN3 1365 NM_001306 0001666 // response to hypoxia // inferred from expression pattern /// 0007165 // signal transduction // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 203955_at NM_014811 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014811.1 /DEF=Homo sapiens KIAA0649 gene product (KIAA0649), mRNA. /FEA=mRNA /GEN=KIAA0649 /PROD=KIAA0649 gene product /DB_XREF=gi:7662223 /UG=Hs.26163 KIAA0649 gene product /FL=gb:AB014549.1 gb:NM_014811.1" NM_014811 "protein phosphatase 1, regulatory subunit 26" PPP1R26 9858 NM_014811 /// XM_005263411 /// XM_005263412 /// XM_006717340 /// XM_006717341 /// XM_006717342 0010923 // negative regulation of phosphatase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 203956_at NM_014941 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014941.1 /DEF=Homo sapiens KIAA0852 protein (KIAA0852), mRNA. /FEA=mRNA /GEN=KIAA0852 /PROD=KIAA0852 protein /DB_XREF=gi:7662339 /UG=Hs.35276 KIAA0852 protein /FL=gb:AB020659.1 gb:NM_014941.1" NM_014941 MORC family CW-type zinc finger 2 MORC2 22880 NM_014941 /// XM_005261391 /// XM_005261392 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203957_at NM_001952 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001952.2 /DEF=Homo sapiens E2F transcription factor 6 (E2F6), mRNA. /FEA=mRNA /GEN=E2F6 /PROD=E2F transcription factor 6 /DB_XREF=gi:12669917 /UG=Hs.42287 E2F transcription factor 6 /FL=gb:NM_001952.2 gb:AF059292.1" NM_001952 E2F transcription factor 6 E2F6 1876 NM_001278275 /// NM_001278276 /// NM_001278277 /// NM_001278278 /// NM_198256 /// NM_198257 /// NM_198258 /// NM_198325 /// NM_212540 /// NR_103490 /// XM_005246154 /// XM_005246155 "0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement 203958_s_at AI557467 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI557467 /FEA=EST /DB_XREF=gi:4489830 /DB_XREF=est:PT2.1_7_F07.r /UG=Hs.4236 KIAA0478 gene product /FL=gb:AB007947.1 gb:NM_014870.1 AI557467 zinc finger and BTB domain containing 40 ZBTB40 9923 NM_001083621 /// NM_014870 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0030282 // bone mineralization // non-traceable author statement" 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203959_s_at NM_014870 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014870.1 /DEF=Homo sapiens KIAA0478 gene product (KIAA0478), mRNA. /FEA=mRNA /GEN=KIAA0478 /PROD=KIAA0478 gene product /DB_XREF=gi:7662153 /UG=Hs.4236 KIAA0478 gene product /FL=gb:AB007947.1 gb:NM_014870.1" NM_014870 zinc finger and BTB domain containing 40 ZBTB40 9923 NM_001083621 /// NM_014870 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0030282 // bone mineralization // non-traceable author statement" 0005634 // nucleus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203960_s_at NM_016126 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016126.1 /DEF=Homo sapiens HSPCO34 protein (LOC51668), mRNA. /FEA=mRNA /GEN=LOC51668 /PROD=HSPCO34 protein /DB_XREF=gi:7706382 /UG=Hs.46967 HSPCO34 protein /FL=gb:BC005245.1 gb:AF100747.1 gb:NM_016126.1" NM_016126 "heat shock protein family B (small), member 11" HSPB11 51668 NM_016126 /// XM_005270942 /// XM_005270943 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from sequence or structural similarity 0005929 // cilium // inferred from electronic annotation /// 0030992 // intraciliary transport particle B // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0046872 // metal ion binding // inferred from electronic annotation 203961_at AL157398 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL157398 /DEF=Human DNA sequence from clone RP11-56H7 on chromosome 10. Contains ESTs, STSs and GSSs. Contains the gene for the nebulette protein (NEBL, actin-binding Z-disc protein) /FEA=mRNA_1 /DB_XREF=gi:10045326 /UG=Hs.5025 nebulette /FL=gb:NM_006393.1" AL157398 nebulette NEBL 10529 NM_001173484 /// NM_006393 /// NM_016365 /// NM_213569 /// XM_005252342 /// XM_005252343 /// XM_005252344 /// XR_242691 0071691 // cardiac muscle thin filament assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031005 // filamin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 203962_s_at NM_006393 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006393.1 /DEF=Homo sapiens nebulette (NEBL), mRNA. /FEA=mRNA /GEN=NEBL /PROD=nebulette /DB_XREF=gi:5453757 /UG=Hs.5025 nebulette /FL=gb:NM_006393.1" NM_006393 nebulette NEBL 10529 NM_001173484 /// NM_006393 /// NM_016365 /// NM_213569 /// XM_005252342 /// XM_005252343 /// XM_005252344 /// XR_242691 0071691 // cardiac muscle thin filament assembly // inferred from mutant phenotype 0001725 // stress fiber // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030018 // Z disc // inferred from direct assay /// 0031674 // I band // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005523 // tropomyosin binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0008092 // cytoskeletal protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // non-traceable author statement /// 0031005 // filamin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay 203963_at NM_001218 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001218.2 /DEF=Homo sapiens carbonic anhydrase XII (CA12), mRNA. /FEA=mRNA /GEN=CA12 /PROD=carbonic anhydrase XII precursor /DB_XREF=gi:9951924 /UG=Hs.5338 carbonic anhydrase XII /FL=gb:AF037335.1 gb:AF051882.1 gb:NM_001218.2" NM_001218 carbonic anhydrase XII CA12 771 NM_001218 /// NM_001293642 /// NM_206925 0006730 // one-carbon metabolic process // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004089 // carbonate dehydratase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203964_at NM_004688 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004688.1 /DEF=Homo sapiens N-myc (and STAT) interactor (NMI), mRNA. /FEA=mRNA /GEN=NMI /PROD=N-myc and STAT interactor /DB_XREF=gi:4758813 /UG=Hs.54483 N-myc (and STAT) interactor /FL=gb:BC001268.1 gb:U32849.1 gb:NM_004688.1" NM_004688 N-myc (and STAT) interactor NMI 9111 NM_004688 /// XM_005246941 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 203965_at NM_006676 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006676.1 /DEF=Homo sapiens ubiquitin specific protease 20 (USP20), mRNA. /FEA=mRNA /GEN=USP20 /PROD=ubiquitin specific protease 20 /DB_XREF=gi:5730107 /UG=Hs.5452 ubiquitin specific protease 20 /FL=gb:AB023220.1 gb:NM_006676.1" NM_006676 ubiquitin specific peptidase 20 USP20 10868 NM_001008563 /// NM_001110303 /// NM_006676 /// XM_005251665 /// XM_005251666 /// XM_006716938 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from mutant phenotype /// 0016579 // protein deubiquitination // inferred from direct assay /// 0070536 // protein K63-linked deubiquitination // inferred from direct assay /// 0071108 // protein K48-linked deubiquitination // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0001664 // G-protein coupled receptor binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from mutant phenotype /// 0004221 // ubiquitin thiolesterase activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0036459 // ubiquitinyl hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203966_s_at NM_021003 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021003.1 /DEF=Homo sapiens protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform (PPM1A), mRNA. /FEA=mRNA /GEN=PPM1A /PROD=protein phosphatase 1A (formerly 2C),magnesium-dependent, alpha isoform /DB_XREF=gi:10337594 /UG=Hs.57764 protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform /FL=gb:NM_021003.1" NM_021003 "protein phosphatase, Mg2+/Mn2+ dependent, 1A" PPM1A 5494 NM_021003 /// NM_177951 /// NM_177952 /// XM_005267777 /// XM_005267778 /// XM_005267779 /// XM_005267780 /// XM_005267781 /// XM_006720179 /// XM_006720180 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006470 // protein dephosphorylation // inferred from mutant phenotype /// 0006499 // N-terminal protein myristoylation // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010991 // negative regulation of SMAD protein complex assembly // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from direct assay /// 0016311 // dephosphorylation // inferred from direct assay /// 0030177 // positive regulation of Wnt signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0035970 // peptidyl-threonine dephosphorylation // inferred from direct assay /// 0042347 // negative regulation of NF-kappaB import into nucleus // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0033192 // calmodulin-dependent protein phosphatase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070412 // R-SMAD binding // inferred from physical interaction 203967_at U77949 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U77949.1 /DEF=Human Cdc6-related protein (HsCDC6) mRNA, complete cds. /FEA=mRNA /GEN=HsCDC6 /PROD=Cdc6-related protein /DB_XREF=gi:1684902 /UG=Hs.69563 CDC6 (cell division cycle 6, S. cerevisiae) homolog /FL=gb:U77949.1 gb:AF022109.1 gb:NM_001254.1" U77949 cell division cycle 6 CDC6 990 NM_001254 0000076 // DNA replication checkpoint // traceable author statement /// 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051984 // positive regulation of chromosome segregation // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0051233 // spindle midzone // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 203968_s_at NM_001254 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001254.1 /DEF=Homo sapiens CDC6 (cell division cycle 6, S. cerevisiae) homolog (CDC6), mRNA. /FEA=mRNA /GEN=CDC6 /PROD=CDC6 (cell division cycle 6, S. cerevisiae)homolog /DB_XREF=gi:4502702 /UG=Hs.69563 CDC6 (cell division cycle 6, S. cerevisiae) homolog /FL=gb:U77949.1 gb:AF022109.1 gb:NM_001254.1" NM_001254 cell division cycle 6 CDC6 990 NM_001254 0000076 // DNA replication checkpoint // traceable author statement /// 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030071 // regulation of mitotic metaphase/anaphase transition // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051984 // positive regulation of chromosome segregation // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0051233 // spindle midzone // inferred from direct assay 0000166 // nucleotide binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction 203969_at AU157140 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AU157140 /FEA=EST /DB_XREF=gi:11018661 /DB_XREF=est:AU157140 /CLONE=PLACE1006288 /UG=Hs.7277 peroxisomal biogenesis factor 3 /FL=gb:NM_003630.1 gb:AB035307.1 AU157140 peroxisomal biogenesis factor 3 PEX3 8504 NM_003630 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032994 // protein-lipid complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 203970_s_at NM_003630 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003630.1 /DEF=Homo sapiens peroxisomal biogenesis factor 3 (PEX3), mRNA. /FEA=mRNA /GEN=PEX3 /PROD=peroxisomal biogenesis factor 3 /DB_XREF=gi:4505726 /UG=Hs.7277 peroxisomal biogenesis factor 3 /FL=gb:NM_003630.1 gb:AB035307.1" NM_003630 peroxisomal biogenesis factor 3 PEX3 8504 NM_003630 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032994 // protein-lipid complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 203971_at NM_001859 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001859.1 /DEF=Homo sapiens solute carrier family 31 (copper transporters), member 1 (SLC31A1), mRNA. /FEA=mRNA /GEN=SLC31A1 /PROD=solute carrier family 31 (copper transporters),member 1 /DB_XREF=gi:4507014 /UG=Hs.73614 solute carrier family 31 (copper transporters), member 1 /FL=gb:U83460.1 gb:NM_001859.1" NM_001859 "solute carrier family 31 (copper transporter), member 1" SLC31A1 1317 NM_001859 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // traceable author statement /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005375 // copper ion transmembrane transporter activity // inferred from electronic annotation 203972_s_at AB035307 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB035307.1 /DEF=Homo sapiens mRNA for Pex3p, complete cds. /FEA=mRNA /GEN=PEX3 /PROD=Pex3p /DB_XREF=gi:8926848 /UG=Hs.7277 peroxisomal biogenesis factor 3 /FL=gb:NM_003630.1 gb:AB035307.1" AB035307 peroxisomal biogenesis factor 3 PEX3 8504 NM_003630 0007031 // peroxisome organization // inferred from mutant phenotype /// 0016557 // peroxisome membrane biogenesis // inferred from electronic annotation /// 0045046 // protein import into peroxisome membrane // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from mutant phenotype /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032994 // protein-lipid complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from direct assay 203973_s_at NM_005195 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005195.1 /DEF=Homo sapiens CCAATenhancer binding protein (CEBP), delta (CEBPD), mRNA. /FEA=mRNA /GEN=CEBPD /PROD=CCAATenhancer binding protein (CEBP), delta /DB_XREF=gi:4885130 /UG=Hs.76722 CCAATenhancer binding protein (CEBP), delta /FL=gb:M83667.1 gb:NM_005195.1" NM_005195 "CCAAT/enhancer binding protein (C/EBP), delta" CEBPD 1052 NM_005195 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 203974_at NM_012080 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012080.1 /DEF=Homo sapiens DNA segment, numerous copies, expressed probes (GS1 gene) (DXF68S1E), mRNA. /FEA=mRNA /GEN=DXF68S1E /PROD=DNA segment, numerous copies, expressed probes(GS1 gene) /DB_XREF=gi:6912345 /UG=Hs.78991 DNA segment, numerous copies, expressed probes (GS1 gene) /FL=gb:M86934.1 gb:NM_012080.1" NM_012080 haloacid dehalogenase-like hydrolase domain containing 1 HDHD1 8226 NM_001135565 /// NM_001178135 /// NM_001178136 /// NM_012080 0008152 // metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0070062 // extracellular vesicular exosome // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 203975_s_at BF000239 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF000239 /FEA=EST /DB_XREF=gi:10700514 /DB_XREF=est:7h24b08.x1 /CLONE=IMAGE:3316887 /UG=Hs.79018 chromatin assembly factor 1, subunit A (p150) /FL=gb:NM_005483.1 gb:U20979.1" BF000239 "chromatin assembly factor 1, subunit A (p150)" CHAF1A 10036 NM_005483 "0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0033186 // CAF-1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071778 // WINAC complex // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement /// 0070087 // chromo shadow domain binding // inferred from physical interaction 203976_s_at NM_005483 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005483.1 /DEF=Homo sapiens chromatin assembly factor 1, subunit A (p150) (CHAF1A), mRNA. /FEA=mRNA /GEN=CHAF1A /PROD=chromatin assembly factor 1, subunit A (p150) /DB_XREF=gi:4885106 /UG=Hs.79018 chromatin assembly factor 1, subunit A (p150) /FL=gb:NM_005483.1 gb:U20979.1" NM_005483 "chromatin assembly factor 1, subunit A (p150)" CHAF1A 10036 NM_005483 "0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006335 // DNA replication-dependent nucleosome assembly // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031497 // chromatin assembly // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0033186 // CAF-1 complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071778 // WINAC complex // inferred from direct assay 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // traceable author statement /// 0070087 // chromo shadow domain binding // inferred from physical interaction 203977_at NM_000116 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000116.1 /DEF=Homo sapiens tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) (TAZ), mRNA. /FEA=mRNA /GEN=TAZ /PROD=tafazzin /DB_XREF=gi:4507370 /UG=Hs.79021 tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) /FL=gb:NM_000116.1" NM_000116 tafazzin TAZ 6901 NM_000116 /// NM_181311 /// NM_181312 /// NM_181313 /// NM_181314 /// NR_024048 /// XM_006724836 /// XM_006724837 /// XM_006724838 /// XM_006724839 /// XM_006724840 /// XM_006724841 /// XM_006724842 0006644 // phospholipid metabolic process // traceable author statement /// 0006936 // muscle contraction // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0007519 // skeletal muscle tissue development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0032049 // cardiolipin biosynthetic process // inferred from mutant phenotype /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype /// 0035965 // cardiolipin acyl-chain remodeling // traceable author statement /// 0042407 // cristae formation // inferred from mutant phenotype /// 0042775 // mitochondrial ATP synthesis coupled electron transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred by curator /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from direct assay" 203978_at NM_002484 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002484.1 /DEF=Homo sapiens nucleotide binding protein 1 (E.coli MinD like) (NUBP1), mRNA. /FEA=mRNA /GEN=NUBP1 /PROD=nucleotide binding protein 1 (E.coli MinD like) /DB_XREF=gi:4505336 /UG=Hs.81469 nucleotide binding protein 1 (E.coli MinD like) /FL=gb:NM_002484.1 gb:U01833.1" NM_002484 nucleotide binding protein 1 NUBP1 4682 NM_001278506 /// NM_002484 /// XM_006720886 0006879 // cellular iron ion homeostasis // inferred from mutant phenotype /// 0010826 // negative regulation of centrosome duplication // inferred from electronic annotation /// 0016049 // cell growth // inferred from mutant phenotype /// 0016226 // iron-sulfur cluster assembly // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0051642 // centrosome localization // inferred from electronic annotation /// 0072697 // protein localization to cell cortex // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from direct assay /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation" 203979_at NM_000784 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000784.1 /DEF=Homo sapiens cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 (CYP27A1), mRNA. /FEA=mRNA /GEN=CYP27A1 /PROD=cytochrome P450, subfamily XXVIIA (steroid27-hydroxylase, cerebrotendinous xanthomatosis),polypeptide 1 /DB_XREF=gi:4503210 /UG=Hs.82568 cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 /FL=gb:M62401.1 gb:NM_000784.1" NM_000784 "cytochrome P450, family 27, subfamily A, polypeptide 1" CYP27A1 1593 NM_000784 0006699 // bile acid biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016125 // sterol metabolic process // traceable author statement /// 0036378 // calcitriol biosynthetic process from calciol // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030343 // vitamin D3 25-hydroxylase activity // inferred from electronic annotation /// 0031073 // cholesterol 26-hydroxylase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047749 // cholestanetriol 26-monooxygenase activity // inferred from electronic annotation" 203980_at NM_001442 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001442.1 /DEF=Homo sapiens fatty acid binding protein 4, adipocyte (FABP4), mRNA. /FEA=mRNA /GEN=FABP4 /PROD=fatty acid binding protein 4, adipocyte /DB_XREF=gi:4557578 /UG=Hs.83213 fatty acid binding protein 4, adipocyte /FL=gb:BC003672.1 gb:J02874.1 gb:NM_001442.1" NM_001442 "fatty acid binding protein 4, adipocyte" FABP4 2167 NM_001442 "0001816 // cytokine production // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005811 // lipid particle // traceable author statement 0005215 // transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation 203981_s_at AL574660 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL574660 /FEA=EST /DB_XREF=gi:12935072 /DB_XREF=est:AL574660 /CLONE=CS0DI065YF14 (3 prime) /UG=Hs.94395 ATP-binding cassette, sub-family D (ALD), member 4 /FL=gb:AF009746.1 gb:NM_005050.1" AL574660 "ATP-binding cassette, sub-family D (ALD), member 4" ABCD4 5826 NM_005050 /// NM_020324 /// NM_020325 /// NM_020326 /// NR_003256 /// XM_005267936 /// XM_005267938 /// XM_005267939 /// XM_005267940 /// XM_005267941 /// XM_005267942 /// XM_005267946 /// XM_005267949 /// XM_005267951 /// XM_005267952 /// XM_005267953 /// XM_005267954 /// XM_006720223 /// XR_245710 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // non-traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement" 203982_s_at NM_005050 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005050.1 /DEF=Homo sapiens ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 1, mRNA. /FEA=mRNA /GEN=ABCD4 /PROD=ATP-binding cassette, sub-family D, member 4,isoform 1 /DB_XREF=gi:4826957 /UG=Hs.94395 ATP-binding cassette, sub-family D (ALD), member 4 /FL=gb:AF009746.1 gb:NM_005050.1" NM_005050 "ATP-binding cassette, sub-family D (ALD), member 4" ABCD4 5826 NM_005050 /// NM_020324 /// NM_020325 /// NM_020326 /// NR_003256 /// XM_005267936 /// XM_005267938 /// XM_005267939 /// XM_005267940 /// XM_005267941 /// XM_005267942 /// XM_005267946 /// XM_005267949 /// XM_005267951 /// XM_005267952 /// XM_005267953 /// XM_005267954 /// XM_006720223 /// XR_245710 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // inferred from mutant phenotype /// 0055085 // transmembrane transport // non-traceable author statement 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043190 // ATP-binding cassette (ABC) transporter complex // non-traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // non-traceable author statement" 203983_at NM_005999 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005999.1 /DEF=Homo sapiens translin-associated factor X (TSNAX), mRNA. /FEA=mRNA /GEN=TSNAX /PROD=translin-associated factor X /DB_XREF=gi:5174730 /UG=Hs.96247 translin-associated factor X /FL=gb:NM_005999.1" NM_005999 translin-associated factor X TSNAX 7257 NM_005999 0000226 // microtubule cytoskeleton organization // inferred from mutant phenotype /// 0001764 // neuron migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from mutant phenotype /// 0002052 // positive regulation of neuroblast proliferation // inferred from electronic annotation /// 0002052 // positive regulation of neuroblast proliferation // inferred from genetic interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0015031 // protein transport // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0021799 // cerebral cortex radially oriented cell migration // inferred from electronic annotation /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from genetic interaction /// 0031929 // TOR signaling // inferred from electronic annotation /// 0051560 // mitochondrial calcium ion homeostasis // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0090128 // regulation of synapse maturation // inferred from electronic annotation /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008565 // protein transporter activity // traceable author statement /// 0031687 // A2A adenosine receptor binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 203984_s_at U60521 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U60521.1 /DEF=Human protease proMch6 (Mch6) mRNA, complete cds. /FEA=mRNA /GEN=Mch6 /PROD=proMch6 /DB_XREF=gi:1532150 /UG=Hs.100641 caspase 9, apoptosis-related cysteine protease /FL=gb:BC002452.1 gb:U56390.1 gb:U60521.1 gb:NM_001229.1" U60521 "caspase 9, apoptosis-related cysteine peptidase" CASP9 842 NM_001229 /// NM_001278054 /// NM_032996 /// NR_102732 /// NR_102733 /// XM_005246014 /// XR_426635 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from mutant phenotype /// 0008635 // activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c // traceable author statement /// 0009411 // response to UV // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030220 // platelet formation // traceable author statement /// 0032025 // response to cobalt ion // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0034644 // cellular response to UV // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042770 // signal transduction in response to DNA damage // inferred from direct assay /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071549 // cellular response to dexamethasone stimulus // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 2001020 // regulation of response to DNA damage stimulus // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0043293 // apoptosome // inferred from direct assay 0004197 // cysteine-type endopeptidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from direct assay 203985_at NM_012256 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012256.1 /DEF=Homo sapiens zinc finger protein 212 (ZNF212), mRNA. /FEA=mRNA /GEN=ZNF212 /PROD=zinc finger protein 212 /DB_XREF=gi:6912749 /UG=Hs.108139 zinc finger protein 212 /FL=gb:U38864.1 gb:NM_012256.1" NM_012256 zinc finger protein 212 ZNF212 7988 NM_012256 /// XM_005250055 /// XM_006716133 /// XM_006716134 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 203986_at NM_003943 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003943.1 /DEF=Homo sapiens genethonin 1 (GENX-3414), mRNA. /FEA=mRNA /GEN=GENX-3414 /PROD=genethonin 1 /DB_XREF=gi:4503976 /UG=Hs.109590 genethonin 1 /FL=gb:AF062534.1 gb:NM_003943.1" NM_003943 "family with sequence similarity 47, member E /// FAM47E-STBD1 readthrough /// starch binding domain 1" FAM47E /// FAM47E-STBD1 /// STBD1 8987 /// 100129583 /// 100631383 NM_001136570 /// NM_001242936 /// NM_001242939 /// NM_003943 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 2001070 // starch binding // inferred from electronic annotation 203987_at NM_003506 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003506.1 /DEF=Homo sapiens frizzled (Drosophila) homolog 6 (FZD6), mRNA. /FEA=mRNA /GEN=FZD6 /PROD=frizzled 6 /DB_XREF=gi:4503830 /UG=Hs.114218 frizzled (Drosophila) homolog 6 /FL=gb:AB012911.1 gb:NM_003506.1 gb:AF072873.1" NM_003506 frizzled class receptor 6 FZD6 8323 NM_001164615 /// NM_001164616 /// NM_003506 /// XR_428385 "0001525 // angiogenesis // not recorded /// 0001736 // establishment of planar polarity // not recorded /// 0001843 // neural tube closure // not recorded /// 0001942 // hair follicle development // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0008406 // gonad development // not recorded /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation /// 0030901 // midbrain development // inferred from electronic annotation /// 0033278 // cell proliferation in midbrain // not recorded /// 0035567 // non-canonical Wnt signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // not recorded /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype" 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016327 // apicolateral plasma membrane // not recorded /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // not recorded /// 0017147 // Wnt-protein binding // inferred from sequence or structural similarity /// 0030165 // PDZ domain binding // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // inferred from direct assay 203988_s_at NM_004480 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004480.1 /DEF=Homo sapiens fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (FUT8), mRNA. /FEA=mRNA /GEN=FUT8 /PROD=fucosyltransferase 8 (alpha (1,6)fucosyltransferase) /DB_XREF=gi:4758407 /UG=Hs.118722 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) /FL=gb:D89289.1 gb:NM_004480.1" NM_004480 "fucosyltransferase 8 (alpha (1,6) fucosyltransferase)" FUT8 2530 NM_004480 /// NM_178154 /// NM_178155 /// NM_178156 /// NM_178157 /// NR_038167 /// NR_038170 /// XM_006720096 /// XM_006720097 0001701 // in utero embryonic development // non-traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006487 // protein N-linked glycosylation // traceable author statement /// 0006491 // N-glycan processing // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0018279 // protein N-linked glycosylation via asparagine // inferred from direct assay /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0033578 // protein glycosylation in Golgi // inferred from electronic annotation /// 0036065 // fucosylation // inferred from electronic annotation /// 0036071 // N-glycan fucosylation // inferred from direct assay /// 0036071 // N-glycan fucosylation // inferred from electronic annotation /// 0036071 // N-glycan fucosylation // traceable author statement /// 0042355 // L-fucose catabolic process // non-traceable author statement /// 0043112 // receptor metabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0046368 // GDP-L-fucose metabolic process // inferred from direct assay 0000139 // Golgi membrane // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // non-traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005515 // protein binding // inferred from electronic annotation /// 0008424 // glycoprotein 6-alpha-L-fucosyltransferase activity // inferred from direct assay /// 0008424 // glycoprotein 6-alpha-L-fucosyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046921 // alpha-(1->6)-fucosyltransferase activity // inferred from electronic annotation" 203989_x_at NM_001992 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001992.2 /DEF=Homo sapiens coagulation factor II (thrombin) receptor (F2R), mRNA. /FEA=mRNA /GEN=F2R /PROD=coagulation factor II receptor precursor /DB_XREF=gi:6031164 /UG=Hs.128087 coagulation factor II (thrombin) receptor /FL=gb:BC002464.1 gb:M62424.1 gb:NM_001992.2" NM_001992 coagulation factor II (thrombin) receptor F2R 2149 NM_001992 "0000186 // activation of MAPKK activity // inferred from sequence or structural similarity /// 0002248 // connective tissue replacement involved in inflammatory response wound healing // inferred from direct assay /// 0003105 // negative regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from sequence or structural similarity /// 0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007260 // tyrosine phosphorylation of STAT protein // inferred from direct assay /// 0007262 // STAT protein import into nucleus // inferred from direct assay /// 0007529 // establishment of synaptic specificity at neuromuscular junction // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009611 // response to wounding // inferred from direct assay /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016265 // death // inferred from electronic annotation /// 0030168 // platelet activation // inferred from direct assay /// 0030168 // platelet activation // traceable author statement /// 0030193 // regulation of blood coagulation // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032651 // regulation of interleukin-1 beta production // inferred from sequence or structural similarity /// 0032967 // positive regulation of collagen biosynthetic process // inferred from direct assay /// 0035025 // positive regulation of Rho protein signal transduction // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045907 // positive regulation of vasoconstriction // inferred from sequence or structural similarity /// 0045987 // positive regulation of smooth muscle contraction // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from direct assay /// 0048873 // homeostasis of number of cells within a tissue // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051281 // positive regulation of release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from sequence or structural similarity /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0051930 // regulation of sensory perception of pain // inferred from sequence or structural similarity /// 0060155 // platelet dense granule organization // inferred by curator /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070493 // thrombin receptor signaling pathway // inferred from electronic annotation /// 1900134 // negative regulation of renin secretion into blood stream // inferred from sequence or structural similarity /// 2000484 // positive regulation of interleukin-8 secretion // inferred from direct assay /// 2000778 // positive regulation of interleukin-6 secretion // inferred from direct assay" 0005576 // extracellular region // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005901 // caveola // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity 0001965 // G-protein alpha-subunit binding // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from sequence or structural similarity /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0015057 // thrombin receptor activity // inferred from direct assay /// 0031681 // G-protein beta-subunit binding // inferred from sequence or structural similarity 203990_s_at AI140752 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI140752 /FEA=EST /DB_XREF=gi:3648209 /DB_XREF=est:qa50e08.x1 /CLONE=IMAGE:1690214 /UG=Hs.13980 ubiquitously transcribed tetratricopeptide repeat gene, X chromosome /FL=gb:NM_021140.1 gb:AF000992.1 gb:AF000993.1" AI140752 lysine (K)-specific demethylase 6A KDM6A 7403 NM_001291415 /// NM_001291416 /// NM_001291417 /// NM_001291418 /// NM_001291421 /// NM_021140 /// NR_111960 /// XM_005272655 /// XM_005272656 /// XM_005272657 /// XM_005272658 /// XM_005272659 /// XM_005272660 /// XM_005272661 /// XR_430507 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from electronic annotation 203991_s_at NM_021140 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021140.1 /DEF=Homo sapiens ubiquitously transcribed tetratricopeptide repeat gene, X chromosome (UTX), mRNA. /FEA=mRNA /GEN=UTX /PROD=ubiquitously transcribed tetratricopeptiderepeat gene, X chromosome /DB_XREF=gi:10863942 /UG=Hs.13980 ubiquitously transcribed tetratricopeptide repeat gene, X chromosome /FL=gb:NM_021140.1 gb:AF000992.1 gb:AF000993.1" NM_021140 lysine (K)-specific demethylase 6A KDM6A 7403 NM_001291415 /// NM_001291416 /// NM_001291417 /// NM_001291418 /// NM_001291421 /// NM_021140 /// NR_111960 /// XM_005272655 /// XM_005272656 /// XM_005272657 /// XM_005272658 /// XM_005272659 /// XM_005272660 /// XM_005272661 /// XR_430507 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from electronic annotation 203992_s_at AF000992 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF000992.1 /DEF=Homo sapiens ubiquitous TPR motif, X isoform (UTX) mRNA, alternative transcript 1, complete cds. /FEA=mRNA /GEN=UTX /PROD=ubiquitous TPR motif, X isoform /DB_XREF=gi:2580569 /UG=Hs.13980 ubiquitously transcribed tetratricopeptide repeat gene, X chromosome /FL=gb:NM_021140.1 gb:AF000992.1 gb:AF000993.1" AF000992 lysine (K)-specific demethylase 6A KDM6A 7403 NM_001291415 /// NM_001291416 /// NM_001291417 /// NM_001291418 /// NM_001291421 /// NM_021140 /// NR_111960 /// XM_005272655 /// XM_005272656 /// XM_005272657 /// XM_005272658 /// XM_005272659 /// XM_005272660 /// XM_005272661 /// XR_430507 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0003016 // respiratory system process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032525 // somite rostral/caudal axis specification // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048570 // notochord morphogenesis // inferred from electronic annotation /// 0051568 // histone H3-K4 methylation // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0071557 // histone H3-K27 demethylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0035097 // histone methyltransferase complex // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation /// 0071558 // histone demethylase activity (H3-K27 specific) // inferred from electronic annotation 203993_x_at U84569 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:U84569.1 /DEF=Human YF5 mRNA, complete cds. /FEA=mRNA /PROD=YF5 /DB_XREF=gi:1835524 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1" U84569 /// chromosome 21 open reading frame 2 AP001062.7 /// C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203994_s_at U84569 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U84569.1 /DEF=Human YF5 mRNA, complete cds. /FEA=mRNA /PROD=YF5 /DB_XREF=gi:1835524 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1" U84569 chromosome 21 open reading frame 2 C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203995_at NM_004928 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004928.1 /DEF=Homo sapiens chromosome 21 open reading frame 2 (C21ORF2), mRNA. /FEA=mRNA /GEN=C21ORF2 /PROD=chromosome 21 open reading frame 2 /DB_XREF=gi:4826650 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1" NM_004928 chromosome 21 open reading frame 2 C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203996_s_at NM_004928 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004928.1 /DEF=Homo sapiens chromosome 21 open reading frame 2 (C21ORF2), mRNA. /FEA=mRNA /GEN=C21ORF2 /PROD=chromosome 21 open reading frame 2 /DB_XREF=gi:4826650 /UG=Hs.153452 chromosome 21 open reading frame 2 /FL=gb:U84569.1 gb:NM_004928.1" NM_004928 chromosome 21 open reading frame 2 C21orf2 755 NM_001271440 /// NM_001271441 /// NM_001271442 /// NM_004928 /// XM_006724051 /// XM_006724052 /// XM_006724053 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0030030 // cell projection organization // inferred from electronic annotation /// 0060271 // cilium morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 203997_at NM_002829 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002829.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), mRNA. /FEA=mRNA /GEN=PTPN3 /PROD=protein tyrosine phosphatase, non-receptor type3 /DB_XREF=gi:4506292 /UG=Hs.153932 protein tyrosine phosphatase, non-receptor type 3 /FL=gb:M64572.1 gb:NM_002829.1" NM_002829 "protein tyrosine phosphatase, non-receptor type 3" PTPN3 5774 NM_001145368 /// NM_001145369 /// NM_001145370 /// NM_001145371 /// NM_001145372 /// NM_002829 /// NR_026918 /// XM_006717197 /// XM_006717198 /// XM_006717199 /// XM_006717200 /// XM_006717201 /// XM_006717202 /// XM_006717203 /// XM_006717204 /// XM_006717205 /// XM_006717206 /// XM_006717207 0006470 // protein dephosphorylation // inferred from direct assay /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement /// 0045930 // negative regulation of mitotic cell cycle // inferred from direct assay /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0001784 // phosphotyrosine binding // inferred from physical interaction /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction 203998_s_at AV723167 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV723167 /FEA=EST /DB_XREF=gi:10826344 /DB_XREF=est:AV723167 /CLONE=HTBAOF10 /UG=Hs.154679 synaptotagmin I /FL=gb:M55047.1 gb:NM_005639.1 AV723167 synaptotagmin I SYT1 6857 NM_001135805 /// NM_001135806 /// NM_001291901 /// NM_005639 /// XM_005269113 /// XM_006719576 0005513 // detection of calcium ion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // traceable author statement /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from electronic annotation /// 0051260 // protein homooligomerization // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060201 // clathrin-sculpted acetylcholine transport vesicle membrane // traceable author statement /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement "0000149 // SNARE binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // traceable author statement /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay" 203999_at AV731490 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AV731490 /FEA=EST /DB_XREF=gi:10840911 /DB_XREF=est:AV731490 /CLONE=HTFAZD04 /UG=Hs.154679 synaptotagmin I /FL=gb:M55047.1 gb:NM_005639.1 AV731490 synaptotagmin I SYT1 6857 NM_001135805 /// NM_001135806 /// NM_001291901 /// NM_005639 /// XM_005269113 /// XM_006719576 0005513 // detection of calcium ion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // traceable author statement /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from electronic annotation /// 0051260 // protein homooligomerization // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060201 // clathrin-sculpted acetylcholine transport vesicle membrane // traceable author statement /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement "0000149 // SNARE binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // traceable author statement /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay" 204000_at NM_016194 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016194.1 /DEF=Homo sapiens hypothetical protein (DKFZp586O1922), mRNA. /FEA=mRNA /GEN=DKFZp586O1922 /PROD=hypothetical protein /DB_XREF=gi:7705366 /UG=Hs.155090 hypothetical protein /FL=gb:AL117471.1 gb:NM_016194.1" NM_016194 "guanine nucleotide binding protein (G protein), beta 5" GNB5 10681 NM_006578 /// NM_016194 "0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 1901386 // negative regulation of voltage-gated calcium channel activity // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation 0003924 // GTPase activity // non-traceable author statement /// 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031682 // G-protein gamma-subunit binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction 204001_at NM_003084 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003084.1 /DEF=Homo sapiens small nuclear RNA activating complex, polypeptide 3, 50kD (SNAPC3), mRNA. /FEA=mRNA /GEN=SNAPC3 /PROD=small nuclear RNA activating complex,polypeptide 3, 50kD /DB_XREF=gi:4507104 /UG=Hs.164915 small nuclear RNA activating complex, polypeptide 3, 50kD /FL=gb:U66413.1 gb:NM_003084.1" NM_003084 "small nuclear RNA activating complex, polypeptide 3, 50kDa" SNAPC3 6619 NM_001039697 /// NM_003084 /// XR_428427 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation 204002_s_at NM_022307 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022307.1 /DEF=Homo sapiens islet cell autoantigen 1 (69kD) (ICA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=ICA1 /PROD=islet cell autoantigen 1, isoform 1 /DB_XREF=gi:12545394 /UG=Hs.167927 islet cell autoantigen 1 (69kD) /FL=gb:NM_022307.1 gb:U26591.1" NM_022307 "islet cell autoantigen 1, 69kDa" ICA1 3382 NM_001136020 /// NM_001276478 /// NM_004968 /// NM_022307 /// NM_022308 /// XM_005249735 /// XM_005249736 /// XM_006715717 /// XM_006715718 /// XM_006715719 /// XM_006715720 /// XM_006715721 0006810 // transport // inferred from electronic annotation /// 0006836 // neurotransmitter transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030658 // transport vesicle membrane // inferred from electronic annotation /// 0030667 // secretory granule membrane // inferred from direct assay /// 0030672 // synaptic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0019904 // protein domain specific binding // inferred from electronic annotation 204003_s_at NM_007342 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007342.1 /DEF=Homo sapiens nucleoporin-like protein 1 (NLP_1), mRNA. /FEA=mRNA /GEN=NLP_1 /PROD=nucleoporin-like protein 1 /DB_XREF=gi:6679073 /UG=Hs.168352 nucleoporin-like protein 1 /FL=gb:U97198.1 gb:NM_007342.1" NM_007342 nucleoporin like 2 NUPL2 11097 NM_007342 /// XM_005249592 /// XM_005249593 0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006611 // protein export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005049 // nuclear export signal receptor activity // traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204004_at AI336206 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI336206 /FEA=EST /DB_XREF=gi:4073133 /DB_XREF=est:qt44e12.x1 /CLONE=IMAGE:1950862 /UG=Hs.176090 PRKC, apoptosis, WT1, regulator /FL=gb:U63809.1 gb:NM_002583.1" AI336206 "PRKC, apoptosis, WT1, regulator" PAWR 5074 NM_002583 /// XM_006719435 /// XM_006719436 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 204005_s_at NM_002583 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002583.1 /DEF=Homo sapiens PRKC, apoptosis, WT1, regulator (PAWR), mRNA. /FEA=mRNA /GEN=PAWR /PROD=apoptosis response protein /DB_XREF=gi:4505612 /UG=Hs.176090 PRKC, apoptosis, WT1, regulator /FL=gb:U63809.1 gb:NM_002583.1" NM_002583 "PRKC, apoptosis, WT1, regulator" PAWR 5074 NM_002583 /// XM_006719435 /// XM_006719436 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030889 // negative regulation of B cell proliferation // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // non-traceable author statement /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from electronic annotation /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005884 // actin filament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay 0003714 // transcription corepressor activity // traceable author statement /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from direct assay /// 0043522 // leucine zipper domain binding // inferred from physical interaction 204006_s_at NM_000570 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000570.1 /DEF=Homo sapiens Fc fragment of IgG, low affinity IIIb, receptor for (CD16) (FCGR3B), mRNA. /FEA=mRNA /GEN=FCGR3B /PROD=Fc fragment of IgG, low affinity IIIb, receptorfor (CD16) /DB_XREF=gi:10835138 /UG=Hs.176663 Fc fragment of IgG, low affinity IIIb, receptor for (CD16) /FL=gb:NM_000570.1 gb:J04162.1 gb:M24854.1 gb:AB025256.1" NM_000570 "Fc fragment of IgG, low affinity IIIa, receptor (CD16a) /// Fc fragment of IgG, low affinity IIIb, receptor (CD16b)" FCGR3A /// FCGR3B 2214 /// 2215 NM_000569 /// NM_000570 /// NM_001127592 /// NM_001127593 /// NM_001127595 /// NM_001127596 /// NM_001244753 /// NM_001271035 /// NM_001271036 /// NM_001271037 /// XM_006710063 /// XM_006710064 /// XM_006711211 0006955 // immune response // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0019864 // IgG binding // inferred from electronic annotation 204007_at J04162 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:J04162.1 /DEF=Human leukocyte IgG receptor (Fc-gamma-R) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183036 /UG=Hs.176663 Fc fragment of IgG, low affinity IIIb, receptor for (CD16) /FL=gb:NM_000570.1 gb:J04162.1 gb:M24854.1 gb:AB025256.1" J04162 "Fc fragment of IgG, low affinity IIIb, receptor (CD16b)" FCGR3B 2215 NM_000570 /// NM_001244753 /// NM_001271035 /// NM_001271036 /// NM_001271037 0006955 // immune response // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0019864 // IgG binding // inferred from electronic annotation 204008_at NM_005740 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005740.1 /DEF=Homo sapiens dynein, axonemal, light polypeptide 4 (DNAL4), mRNA. /FEA=mRNA /GEN=DNAL4 /PROD=dynein, axonemal, light polypeptide 4 /DB_XREF=gi:5031666 /UG=Hs.182595 dynein, axonemal, light polypeptide 4 /FL=gb:BC002968.1 gb:NM_005740.1" NM_005740 "dynein, axonemal, light chain 4" DNAL4 10126 NM_005740 0007017 // microtubule-based process // inferred from electronic annotation /// 0007018 // microtubule-based movement // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005858 // axonemal dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005929 // cilium // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation "0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0042623 // ATPase activity, coupled // non-traceable author statement" 204009_s_at W80678 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:W80678 /FEA=EST /DB_XREF=gi:1391858 /DB_XREF=est:zd90d06.s1 /CLONE=IMAGE:356747 /UG=Hs.184050 v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog /FL=gb:M54968.1 gb:NM_004985.1 W80678 Kirsten rat sarcoma viral oncogene homolog KRAS 3845 NM_004985 /// NM_033360 /// XM_006719069 "0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 204010_s_at NM_004985 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004985.1 /DEF=Homo sapiens v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog (KRAS2), mRNA. /FEA=mRNA /GEN=KRAS2 /PROD=v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogenehomolog /DB_XREF=gi:4826811 /UG=Hs.184050 v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog /FL=gb:M54968.1 gb:NM_004985.1" NM_004985 Kirsten rat sarcoma viral oncogene homolog KRAS 3845 NM_004985 /// NM_033360 /// XM_006719069 "0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0035022 // positive regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0019002 // GMP binding // inferred from electronic annotation /// 0019003 // GDP binding // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from direct assay 204011_at NM_005842 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005842.1 /DEF=Homo sapiens sprouty (Drosophila) homolog 2 (SPRY2), mRNA. /FEA=mRNA /GEN=SPRY2 /PROD=sprouty (Drosophila) homolog 2 /DB_XREF=gi:5032114 /UG=Hs.18676 sprouty (Drosophila) homolog 2 /FL=gb:AF039843.1 gb:NM_005842.1" NM_005842 sprouty homolog 2 (Drosophila) SPRY2 10253 NM_005842 /// XM_005266217 /// XM_006719752 /// XM_006719753 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010801 // negative regulation of peptidyl-threonine phosphorylation // inferred from direct assay /// 0030324 // lung development // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from mutant phenotype /// 0034261 // negative regulation of Ras GTPase activity // inferred from electronic annotation /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043407 // negative regulation of MAP kinase activity // inferred from electronic annotation /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051387 // negative regulation of neurotrophin TRK receptor signaling pathway // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060425 // lung morphogenesis // inferred from electronic annotation /// 0060437 // lung growth // inferred from electronic annotation /// 0060541 // respiratory system development // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071902 // positive regulation of protein serine/threonine kinase activity // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030291 // protein serine/threonine kinase inhibitor activity // inferred by curator /// 0043539 // protein serine/threonine kinase activator activity // inferred from mutant phenotype 204012_s_at AL529189 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL529189 /FEA=EST /DB_XREF=gi:12792682 /DB_XREF=est:AL529189 /CLONE=CS0DD002YM13 (3 prime) /UG=Hs.200596 KIAA0547 gene product /FL=gb:AB011119.1 gb:NM_014793.1 AL529189 leucine carboxyl methyltransferase 2 LCMT2 9836 NM_014793 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204013_s_at NM_014793 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014793.1 /DEF=Homo sapiens KIAA0547 gene product (KIAA0547), mRNA. /FEA=mRNA /GEN=KIAA0547 /PROD=KIAA0547 gene product /DB_XREF=gi:7662173 /UG=Hs.200596 KIAA0547 gene product /FL=gb:AB011119.1 gb:NM_014793.1" NM_014793 leucine carboxyl methyltransferase 2 LCMT2 9836 NM_014793 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204014_at NM_001394 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001394.2 /DEF=Homo sapiens dual specificity phosphatase 4 (DUSP4), mRNA. /FEA=mRNA /GEN=DUSP4 /PROD=dual specificity phosphatase 4 /DB_XREF=gi:12707552 /UG=Hs.2359 dual specificity phosphatase 4 /FL=gb:U48807.1 gb:NM_001394.2 gb:BC002671.1 gb:U21108.1" NM_001394 dual specificity phosphatase 4 DUSP4 1846 NM_001394 /// NM_057158 0000165 // MAPK cascade // traceable author statement /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 204015_s_at BC002671 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002671.1 /DEF=Homo sapiens, dual specificity phosphatase 4, clone MGC:3713, mRNA, complete cds. /FEA=mRNA /PROD=dual specificity phosphatase 4 /DB_XREF=gi:12803670 /UG=Hs.2359 dual specificity phosphatase 4 /FL=gb:U48807.1 gb:NM_001394.2 gb:BC002671.1 gb:U21108.1" BC002671 dual specificity phosphatase 4 DUSP4 1846 NM_001394 /// NM_057158 0000165 // MAPK cascade // traceable author statement /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 204016_at NM_015340 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015340.1 /DEF=Homo sapiens leucyl-tRNA synthetase, mitochondrial (KIAA0028), mRNA. /FEA=mRNA /GEN=KIAA0028 /PROD=leucyl-tRNA synthetase, mitochondrial /DB_XREF=gi:7661871 /UG=Hs.2450 leucyl-tRNA synthetase, mitochondrial /FL=gb:NM_015340.1" NM_015340 "leucyl-tRNA synthetase 2, mitochondrial" LARS2 23395 NM_015340 /// XM_005265006 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006429 // leucyl-tRNA aminoacylation // inferred from electronic annotation /// 0006450 // regulation of translational fidelity // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0002161 // aminoacyl-tRNA editing activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004823 // leucine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 204017_at NM_006855 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006855.2 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 (KDELR3), transcript variant 1, mRNA. /FEA=mRNA /GEN=KDELR3 /PROD=KDEL receptor 3, isoform a /DB_XREF=gi:8051612 /UG=Hs.250696 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 /FL=gb:BC001277.1 gb:NM_006855.2" NM_006855 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 KDELR3 11015 NM_006855 /// NM_016657 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0046923 // ER retention sequence binding // inferred from electronic annotation 204018_x_at NM_000558 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000558.2 /DEF=Homo sapiens hemoglobin, alpha 1 (HBA1), mRNA. /FEA=mRNA /GEN=HBA1 /PROD=hemoglobin, alpha 1 /DB_XREF=gi:6715603 /UG=Hs.251577 hemoglobin, alpha 1 /FL=gb:NM_000558.2" NM_000558 "hemoglobin, alpha 1 /// hemoglobin, alpha 2" HBA1 /// HBA2 3039 /// 3040 NM_000517 /// NM_000558 0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay 0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204019_s_at NM_015677 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015677.1 /DEF=Homo sapiens hypothetical protein (DKFZP586F1318), mRNA. /FEA=mRNA /GEN=DKFZP586F1318 /PROD=hypothetical protein /DB_XREF=gi:7661669 /UG=Hs.25213 hypothetical protein /FL=gb:NM_015677.1" NM_015677 SH3 and SYLF domain containing 1 SH3YL1 26751 NM_001159597 /// NM_001282682 /// NM_001282687 /// NM_015677 /// NR_104223 /// NR_104224 /// NR_104225 /// NR_104226 /// NR_104227 0006661 // phosphatidylinositol biosynthetic process // inferred from electronic annotation /// 1900027 // regulation of ruffle assembly // inferred from electronic annotation 0032587 // ruffle membrane // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay 204020_at BF739943 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF739943 /FEA=EST /DB_XREF=gi:12066607 /DB_XREF=est:7o41b04.x1 /CLONE=IMAGE:3576534 /UG=Hs.29117 purine-rich element binding protein A /FL=gb:M96684.1 gb:NM_005859.1 BF739943 purine-rich element binding protein A PURA 5813 NM_005859 "0006268 // DNA unwinding involved in DNA replication // inferred from direct assay /// 0006270 // DNA replication initiation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation" "0000784 // nuclear chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation" "0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0032422 // purine-rich negative regulatory element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation" 204021_s_at NM_005859 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005859.1 /DEF=Homo sapiens purine-rich element binding protein A (PURA), mRNA. /FEA=mRNA /GEN=PURA /PROD=purine-rich element binding protein A /DB_XREF=gi:5032006 /UG=Hs.29117 purine-rich element binding protein A /FL=gb:M96684.1 gb:NM_005859.1" NM_005859 purine-rich element binding protein A PURA 5813 NM_005859 "0006268 // DNA unwinding involved in DNA replication // inferred from direct assay /// 0006270 // DNA replication initiation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation" "0000784 // nuclear chromosome, telomeric region // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005662 // DNA replication factor A complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation" "0000900 // translation repressor activity, nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003691 // double-stranded telomeric DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from sequence or structural similarity /// 0032422 // purine-rich negative regulatory element binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation" 204022_at AI668780 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI668780 /FEA=EST /DB_XREF=gi:4833554 /DB_XREF=est:wc14b09.x1 /CLONE=IMAGE:2315129 /UG=Hs.315493 Nedd-4-like ubiquitin-protein ligase /FL=gb:U96114.1 gb:NM_007014.2 AI668780 WW domain containing E3 ubiquitin protein ligase 2 WWP2 11060 NM_001270453 /// NM_001270454 /// NM_001270455 /// NM_007014 /// NM_199424 /// XM_005255778 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006464 // cellular protein modification process // traceable author statement /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032410 // negative regulation of transporter activity // inferred from direct assay /// 0034765 // regulation of ion transmembrane transport // inferred from direct assay /// 0042391 // regulation of membrane potential // inferred from direct assay /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0046718 // viral entry into host cell // traceable author statement /// 0051224 // negative regulation of protein transport // inferred from mutant phenotype /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070534 // protein K63-linked ubiquitination // inferred from sequence or structural similarity /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay" 0000151 // ubiquitin ligase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay 0001085 // RNA polymerase II transcription factor binding // inferred from physical interaction /// 0001085 // RNA polymerase II transcription factor binding // inferred from sequence or structural similarity /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 204023_at NM_002916 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002916.1 /DEF=Homo sapiens replication factor C (activator 1) 4 (37kD) (RFC4), mRNA. /FEA=mRNA /GEN=RFC4 /PROD=replication factor C (activator 1) 4 (37kD) /DB_XREF=gi:4506490 /UG=Hs.35120 replication factor C (activator 1) 4 (37kD) /FL=gb:M87339.1 gb:NM_002916.1" NM_002916 "replication factor C (activator 1) 4, 37kDa" RFC4 5984 NM_002916 /// NM_181573 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 204024_at NM_004337 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004337.1 /DEF=Homo sapiens chromosome 8 open reading frame 1 (C8ORF1), mRNA. /FEA=mRNA /GEN=C8ORF1 /PROD=chromosome 8 open reading frame 1 /DB_XREF=gi:4757889 /UG=Hs.40539 chromosome 8 open reading frame 1 /FL=gb:AF061326.1 gb:NM_004337.1" NM_004337 oxidative stress induced growth inhibitor family member 2 OSGIN2 734 NM_001126111 /// NM_004337 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007281 // germ cell development // non-traceable author statement 204025_s_at NM_002598 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002598.1 /DEF=Homo sapiens programmed cell death 2 (PDCD2), mRNA. /FEA=mRNA /GEN=PDCD2 /PROD=programmed cell death 2 /DB_XREF=gi:4505654 /UG=Hs.41639 programmed cell death 2 /FL=gb:NM_002598.1" NM_002598 programmed cell death 2 PDCD2 5134 NM_001199461 /// NM_001199462 /// NM_001199463 /// NM_001199464 /// NM_002598 /// NM_144781 /// XM_006715498 /// XR_427972 0006915 // apoptotic process // inferred from electronic annotation /// 0012501 // programmed cell death // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204026_s_at NM_007057 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007057.1 /DEF=Homo sapiens ZW10 interactor (ZWINT), mRNA. /FEA=mRNA /GEN=ZWINT /PROD=ZW10 interactor /DB_XREF=gi:6857828 /UG=Hs.42650 ZW10 interactor /FL=gb:AF067656.1 gb:NM_007057.1" NM_007057 ZW10 interacting kinetochore protein ZWINT 11130 NM_001005413 /// NM_001005414 /// NM_007057 /// NM_032997 /// XM_005269463 /// XR_428692 /// XR_428693 0000070 // mitotic sister chromatid segregation // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051649 // establishment of localization in cell // inferred from direct assay "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation" 0005515 // protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 204027_s_at NM_005371 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005371.2 /DEF=Homo sapiens methyltransferase-like 1 (METTL1), transcript variant 1, mRNA. /FEA=mRNA /GEN=METTL1 /PROD=methyltransferase-like protein 1, isoform a /DB_XREF=gi:13186321 /UG=Hs.42957 methyltransferase-like 1 /FL=gb:BC000550.1 gb:NM_005371.2" NM_005371 methyltransferase like 1 METTL1 4234 NM_005371 /// NM_023032 /// NM_023033 /// XM_005268873 0006400 // tRNA modification // inferred from direct assay /// 0008033 // tRNA processing // inferred from electronic annotation /// 0030488 // tRNA methylation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0036265 // RNA (guanine-N7)-methylation // inferred from direct assay /// 0036265 // RNA (guanine-N7)-methylation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008176 // tRNA (guanine-N7-)-methyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation 204028_s_at NM_012197 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012197.2 /DEF=Homo sapiens rab6 GTPase activating protein (GAP and centrosome-associated) (GAPCENA), mRNA. /FEA=mRNA /GEN=GAPCENA /PROD=rab6 GTPase activating protein (GAP andcentrosome-associated) /DB_XREF=gi:12232372 /UG=Hs.55099 rab6 GTPase activating protein (GAP and centrosome-associated) /FL=gb:NM_012197.2" NM_012197 RAB GTPase activating protein 1 RABGAP1 23637 NM_012197 /// XM_005251866 /// XM_005251868 /// XM_006717031 /// XM_006717032 0007049 // cell cycle // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // traceable author statement 204029_at NM_001408 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001408.1 /DEF=Homo sapiens cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog (CELSR2), mRNA. /FEA=mRNA /GEN=CELSR2 /PROD=cadherin EGF LAG seven-pass G-type receptor 2 /DB_XREF=gi:13325063 /UG=Hs.57652 cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog /FL=gb:NM_001408.1" NM_001408 "cadherin, EGF LAG seven-pass G-type receptor 2" CELSR2 1952 NM_001408 /// XM_005270580 /// XM_006710405 "0001764 // neuron migration // inferred from electronic annotation /// 0003341 // cilium movement // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from sequence or structural similarity /// 0021591 // ventricular system development // inferred from electronic annotation /// 0021999 // neural plate anterior/posterior regionalization // inferred from sequence or structural similarity /// 0022407 // regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033326 // cerebrospinal fluid secretion // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity" 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 204030_s_at NM_014575 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014575.1 /DEF=Homo sapiens schwannomin interacting protein 1 (SCHIP-1), mRNA. /FEA=mRNA /GEN=SCHIP-1 /PROD=schwannomin interacting protein 1 /DB_XREF=gi:7657539 /UG=Hs.61490 schwannomin interacting protein 1 /FL=gb:AF145713.1 gb:NM_014575.1" NM_014575 IQCJ-SCHIP1 readthrough /// schwannomin interacting protein 1 IQCJ-SCHIP1 /// SCHIP1 29970 /// 100505385 NM_001197107 /// NM_001197108 /// NM_001197109 /// NM_001197113 /// NM_001197114 /// NM_014575 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204031_s_at NM_005016 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005016.1 /DEF=Homo sapiens poly(rC)-binding protein 2 (PCBP2), mRNA. /FEA=mRNA /GEN=PCBP2 /PROD=poly(rC)-binding protein 2 /DB_XREF=gi:4826885 /UG=Hs.63525 poly(rC)-binding protein 2 /FL=gb:BC001155.1 gb:NM_005016.1" NM_005016 poly(rC) binding protein 2 PCBP2 5094 NM_001098620 /// NM_001128911 /// NM_001128912 /// NM_001128913 /// NM_001128914 /// NM_005016 /// NM_031989 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016071 // mRNA metabolic process // non-traceable author statement /// 0032480 // negative regulation of type I interferon production // traceable author statement /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051607 // defense response to virus // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204032_at NM_003567 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003567.1 /DEF=Homo sapiens breast cancer anti-estrogen resistance 3 (BCAR3), mRNA. /FEA=mRNA /GEN=BCAR3 /PROD=breast cancer antiestrogen resistance 3 /DB_XREF=gi:4502370 /UG=Hs.6564 breast cancer anti-estrogen resistance 3 /FL=gb:U92715.1 gb:NM_003567.1 gb:AF124250.1" NM_003567 breast cancer anti-estrogen resistance 3 BCAR3 8412 NM_001261408 /// NM_001261409 /// NM_001261410 /// NM_003567 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204033_at NM_004237 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004237.1 /DEF=Homo sapiens thyroid hormone receptor interactor 13 (TRIP13), mRNA. /FEA=mRNA /GEN=TRIP13 /PROD=thyroid hormone receptor interactor 13 /DB_XREF=gi:11321606 /UG=Hs.6566 thyroid hormone receptor interactor 13 /FL=gb:NM_004237.1 gb:BC000404.1 gb:U96131.1" NM_004237 thyroid hormone receptor interactor 13 TRIP13 9319 NM_001166260 /// NM_004237 /// XM_005248388 0001556 // oocyte maturation // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007130 // synaptonemal complex assembly // inferred from sequence or structural similarity /// 0007131 // reciprocal meiotic recombination // inferred from sequence or structural similarity /// 0007141 // male meiosis I // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007286 // spermatid development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0048477 // oogenesis // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // traceable author statement 0001673 // male germ cell nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204034_at NM_014297 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014297.1 /DEF=Homo sapiens protein expressed in thyroid (YF13H12), mRNA. /FEA=mRNA /GEN=YF13H12 /PROD=protein expressed in thyroid /DB_XREF=gi:7657686 /UG=Hs.7486 protein expressed in thyroid /FL=gb:NM_014297.1" NM_014297 ethylmalonic encephalopathy 1 ETHE1 23474 NM_014297 /// XM_005258687 /// XM_005258688 "0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement /// 0070813 // hydrogen sulfide metabolic process // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement 0005506 // iron ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050313 // sulfur dioxygenase activity // inferred from direct assay /// 0050313 // sulfur dioxygenase activity // traceable author statement /// 0051213 // dioxygenase activity // inferred from electronic annotation 204035_at NM_003469 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003469.2 /DEF=Homo sapiens secretogranin II (chromogranin C) (SCG2), mRNA. /FEA=mRNA /GEN=SCG2 /PROD=secretogranin II precursor /DB_XREF=gi:10800415 /UG=Hs.75426 secretogranin II (chromogranin C) /FL=gb:NM_003469.2 gb:M25756.1" NM_003469 secretogranin II SCG2 7857 NM_003469 0000165 // MAPK cascade // inferred from direct assay /// 0001525 // angiogenesis // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0006928 // cellular component movement // inferred from direct assay /// 0006954 // inflammatory response // traceable author statement /// 0009306 // protein secretion // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043542 // endothelial cell migration // traceable author statement /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050930 // induction of positive chemotaxis // inferred from direct assay /// 2000352 // negative regulation of endothelial cell apoptotic process // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation 0005125 // cytokine activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay 204036_at AW269335 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AW269335 /FEA=EST /DB_XREF=gi:6656365 /DB_XREF=est:xs47d05.x1 /CLONE=IMAGE:2772777 /UG=Hs.75794 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 /FL=gb:U78192.1 gb:U80811.1 gb:NM_001401.1" AW269335 lysophosphatidic acid receptor 1 LPAR1 1902 NM_001401 /// NM_057159 /// XM_005251781 /// XM_005251782 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032060 // bleb assembly // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 204037_at BF055366 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF055366 /FEA=EST /DB_XREF=gi:10809262 /DB_XREF=est:7j78f10.x1 /CLONE=IMAGE:3392587 /UG=Hs.75794 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 /FL=gb:U78192.1 gb:U80811.1 gb:NM_001401.1" BF055366 lysophosphatidic acid receptor 1 LPAR1 1902 NM_001401 /// NM_057159 /// XM_005251781 /// XM_005251782 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032060 // bleb assembly // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 204038_s_at NM_001401 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001401.1 /DEF=Homo sapiens endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 (EDG2), mRNA. /FEA=mRNA /GEN=EDG2 /PROD=endothelial differentiation, lysophosphatidicacid G-protein-coupled receptor, 2 /DB_XREF=gi:4503456 /UG=Hs.75794 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 /FL=gb:U78192.1 gb:U80811.1 gb:NM_001401.1" NM_001401 lysophosphatidic acid receptor 1 LPAR1 1902 NM_001401 /// NM_057159 /// XM_005251781 /// XM_005251782 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // traceable author statement /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0010977 // negative regulation of neuron projection development // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0032060 // bleb assembly // inferred from electronic annotation /// 0035025 // positive regulation of Rho protein signal transduction // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from electronic annotation /// 0060999 // positive regulation of dendritic spine development // inferred from electronic annotation /// 0071453 // cellular response to oxygen levels // inferred from electronic annotation /// 0071673 // positive regulation of smooth muscle cell chemotaxis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043198 // dendritic shaft // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from electronic annotation /// 0070915 // lysophosphatidic acid receptor activity // inferred from electronic annotation 204039_at NM_004364 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004364.1 /DEF=Homo sapiens CCAATenhancer binding protein (CEBP), alpha (CEBPA), mRNA. /FEA=mRNA /GEN=CEBPA /PROD=CCAATenhancer binding protein (CEBP), alpha /DB_XREF=gi:4757971 /UG=Hs.76171 CCAATenhancer binding protein (CEBP), alpha /FL=gb:NM_004364.1" NM_004364 "CCAAT/enhancer binding protein (C/EBP), alpha" CEBPA 1050 NM_001285829 /// NM_001287424 /// NM_001287435 /// NM_004364 "0000050 // urea cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006351 // transcription, DNA-templated // non-traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement /// 0030099 // myeloid cell differentiation // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030225 // macrophage differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033274 // response to vitamin B2 // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045945 // positive regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0048469 // cell maturation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation" 0005634 // nucleus // non-traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0035189 // Rb-E2F complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation 204040_at NM_014746 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014746.1 /DEF=Homo sapiens KIAA0161 gene product (KIAA0161), mRNA. /FEA=mRNA /GEN=KIAA0161 /PROD=KIAA0161 gene product /DB_XREF=gi:7661955 /UG=Hs.78894 KIAA0161 gene product /FL=gb:D79983.1 gb:NM_014746.1" NM_014746 ring finger protein 144A RNF144A 9781 NM_014746 /// XM_005246200 /// XM_005246201 /// XM_005246202 /// XM_005246203 /// XM_006711909 0016567 // protein ubiquitination // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204041_at NM_000898 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000898.1 /DEF=Homo sapiens monoamine oxidase B (MAOB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MAOB /PROD=monoamine oxidase B /DB_XREF=gi:4505092 /UG=Hs.82163 monoamine oxidase B /FL=gb:M69177.1 gb:NM_000898.1" NM_000898 monoamine oxidase B MAOB 4129 NM_000898 /// XM_005272607 /// XM_005272608 0006805 // xenobiotic metabolic process // traceable author statement /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010044 // response to aluminum ion // inferred from electronic annotation /// 0010269 // response to selenium ion // inferred from electronic annotation /// 0014063 // negative regulation of serotonin secretion // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045964 // positive regulation of dopamine metabolic process // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008131 // primary amine oxidase activity // traceable author statement /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204042_at AB020707 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB020707.1 /DEF=Homo sapiens mRNA for KIAA0900 protein, partial cds. /FEA=mRNA /GEN=KIAA0900 /PROD=KIAA0900 protein /DB_XREF=gi:4240288 /UG=Hs.82318 WAS protein family, member 3 /FL=gb:NM_006646.2 gb:AB026543.1" AB020707 "WAS protein family, member 3" WASF3 10810 NM_001291965 /// NM_006646 /// XM_005266239 0006461 // protein complex assembly // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // traceable author statement /// 0031643 // positive regulation of myelination // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 204043_at NM_000355 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000355.1 /DEF=Homo sapiens transcobalamin II; macrocytic anemia (TCN2), mRNA. /FEA=mRNA /GEN=TCN2 /PROD=transcobalamin II /DB_XREF=gi:4507408 /UG=Hs.84232 transcobalamin II; macrocytic anemia /FL=gb:BC001176.1 gb:M60396.1 gb:L02647.1 gb:L02648.1 gb:NM_000355.1" NM_000355 transcobalamin II TCN2 6948 NM_000355 /// NM_001184726 /// NM_001190420 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006824 // cobalt ion transport // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // not recorded /// 0009235 // cobalamin metabolic process // traceable author statement /// 0015889 // cobalamin transport // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // traceable author statement /// 0005768 // endosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0031419 // cobalamin binding // not recorded /// 0031419 // cobalamin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204044_at NM_014298 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014298.2 /DEF=Homo sapiens quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) (QPRT), mRNA. /FEA=mRNA /GEN=QPRT /PROD=quinolinate phosphoribosyltransferase /DB_XREF=gi:9257236 /UG=Hs.8935 quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) /FL=gb:D78177.1 gb:BC005060.1 gb:NM_014298.2" NM_014298 quinolinate phosphoribosyltransferase QPRT 23475 NM_014298 /// XM_005255223 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // traceable author statement /// 0034213 // quinolinate catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046874 // quinolinate metabolic process // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0003824 // catalytic activity // inferred from electronic annotation /// 0004514 // nicotinate-nucleotide diphosphorylase (carboxylating) activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay" 204045_at NM_004780 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004780.1 /DEF=Homo sapiens transcription elongation factor A (SII)-like 1 (TCEAL1), mRNA. /FEA=mRNA /GEN=TCEAL1 /PROD=transcription elongation factor A (SII)-like 1 /DB_XREF=gi:4759215 /UG=Hs.95243 transcription elongation factor A (SII)-like 1 /FL=gb:BC000809.1 gb:NM_004780.1 gb:M99701.1" NM_004780 transcription elongation factor A (SII)-like 1 TCEAL1 9338 NM_001006639 /// NM_001006640 /// NM_004780 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement 204046_at NM_004573 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004573.1 /DEF=Homo sapiens phospholipase C, beta 2 (PLCB2), mRNA. /FEA=mRNA /GEN=PLCB2 /PROD=phospholipase C, beta 2 /DB_XREF=gi:4758937 /UG=Hs.994 phospholipase C, beta 2 /FL=gb:M95678.1 gb:NM_004573.1" NM_004573 "phospholipase C, beta 2" PLCB2 5330 NM_001284297 /// NM_001284298 /// NM_001284299 /// NM_004573 /// XM_005254448 /// XM_005254449 /// XM_005254450 /// XM_006720571 /// XM_006720572 /// XR_243102 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004629 // phospholipase C activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204047_s_at AW295193 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW295193 /FEA=EST /DB_XREF=gi:6701829 /DB_XREF=est:UI-H-BI2-aib-f-02-0-UI.s1 /CLONE=IMAGE:2728827 /UG=Hs.102471 KIAA0680 gene product /FL=gb:AB014580.1 gb:NM_014721.1 AW295193 phosphatase and actin regulator 2 PHACTR2 9749 NM_001100164 /// NM_001100165 /// NM_001100166 /// NM_014721 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204048_s_at AA551142 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA551142 /FEA=EST /DB_XREF=gi:2321394 /DB_XREF=est:nk76a03.s1 /CLONE=IMAGE:1019404 /UG=Hs.102471 KIAA0680 gene product /FL=gb:AB014580.1 gb:NM_014721.1 AA551142 phosphatase and actin regulator 2 PHACTR2 9749 NM_001100164 /// NM_001100165 /// NM_001100166 /// NM_014721 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204049_s_at NM_014721 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014721.1 /DEF=Homo sapiens KIAA0680 gene product (KIAA0680), mRNA. /FEA=mRNA /GEN=KIAA0680 /PROD=KIAA0680 gene product /DB_XREF=gi:7662247 /UG=Hs.102471 KIAA0680 gene product /FL=gb:AB014580.1 gb:NM_014721.1" NM_014721 phosphatase and actin regulator 2 PHACTR2 9749 NM_001100164 /// NM_001100165 /// NM_001100166 /// NM_014721 0043086 // negative regulation of catalytic activity // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204050_s_at NM_001833 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001833.1 /DEF=Homo sapiens clathrin, light polypeptide (Lca) (CLTA), transcript variant nonbrain, mRNA. /FEA=mRNA /GEN=CLTA /PROD=clathrin, light polypeptide A (Lca) isoform a /DB_XREF=gi:4502898 /UG=Hs.104143 clathrin, light polypeptide (Lca) /FL=gb:M20472.1 gb:NM_001833.1" NM_001833 "clathrin, light chain A" CLTA 1211 NM_001076677 /// NM_001184760 /// NM_001184761 /// NM_001184762 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0061024 // membrane organization // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from sequence or structural similarity /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0071439 // clathrin complex // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032050 // clathrin heavy chain binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation 204051_s_at AW089415 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW089415 /FEA=EST /DB_XREF=gi:6046759 /DB_XREF=est:xd05c09.x1 /CLONE=IMAGE:2592880 /UG=Hs.105700 secreted frizzled-related protein 4 /FL=gb:AF026692.1 gb:NM_003014.2 AW089415 secreted frizzled-related protein 4 SFRP4 6424 NM_003014 0001944 // vasculature development // not recorded /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008406 // gonad development // not recorded /// 0009725 // response to hormone // non-traceable author statement /// 0009790 // embryo development // /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0022601 // menstrual cycle phase // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045606 // positive regulation of epidermal cell differentiation // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // not recorded /// 0046697 // decidualization // not recorded /// 0055062 // phosphate ion homeostasis // inferred from direct assay /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 1902174 // positive regulation of keratinocyte apoptotic process // inferred from direct assay /// 2000119 // negative regulation of sodium-dependent phosphate transport // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 204052_s_at NM_003014 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003014.2 /DEF=Homo sapiens secreted frizzled-related protein 4 (SFRP4), mRNA. /FEA=mRNA /GEN=SFRP4 /PROD=secreted frizzled-related protein 4 /DB_XREF=gi:8400733 /UG=Hs.105700 secreted frizzled-related protein 4 /FL=gb:AF026692.1 gb:NM_003014.2" NM_003014 secreted frizzled-related protein 4 SFRP4 6424 NM_003014 0001944 // vasculature development // not recorded /// 0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008406 // gonad development // not recorded /// 0009725 // response to hormone // non-traceable author statement /// 0009790 // embryo development // /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0022601 // menstrual cycle phase // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0045606 // positive regulation of epidermal cell differentiation // inferred from direct assay /// 0046329 // negative regulation of JNK cascade // not recorded /// 0046697 // decidualization // not recorded /// 0055062 // phosphate ion homeostasis // inferred from direct assay /// 0060056 // mammary gland involution // not recorded /// 0060429 // epithelium development // not recorded /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 1902174 // positive regulation of keratinocyte apoptotic process // inferred from direct assay /// 2000119 // negative regulation of sodium-dependent phosphate transport // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0032589 // neuron projection membrane // not recorded 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // not recorded /// 0042813 // Wnt-activated receptor activity // not recorded 204053_x_at U96180 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U96180.1 /DEF=Human protein tyrosine phosphatase (TEP1) mRNA, complete cds. /FEA=mRNA /GEN=TEP1 /PROD=protein tyrosine phosphatase /DB_XREF=gi:2039369 /UG=Hs.10712 phosphatase and tensin homolog (mutated in multiple advanced cancers 1) /FL=gb:U92436.1 gb:U93051.1 gb:U96180.1 gb:NM_000314.1" U96180 phosphatase and tensin homolog PTEN 5728 NM_000314 /// XM_006717926 /// XM_006717927 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007613 // memory // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021955 // central nervous system neuron axonogenesis // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031658 // negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032535 // regulation of cellular component size // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045792 // negative regulation of cell size // inferred from sequence or structural similarity /// 0046621 // negative regulation of organ growth // inferred from sequence or structural similarity /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060024 // rhythmic synaptic transmission // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060074 // synapse maturation // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090071 // negative regulation of ribosome biogenesis // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097107 // postsynaptic density assembly // inferred from sequence or structural similarity /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000808 // negative regulation of synaptic vesicle clustering // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation "0000287 // magnesium ion binding // inferred from electronic annotation /// 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // inferred from direct assay /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // inferred from direct assay /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // traceable author statement /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // inferred from direct assay /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // traceable author statement" 204054_at NM_000314 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000314.1 /DEF=Homo sapiens phosphatase and tensin homolog (mutated in multiple advanced cancers 1) (PTEN), mRNA. /FEA=mRNA /GEN=PTEN /PROD=phosphatase and tensin homolog (mutated inmultiple advanced cancers 1) /DB_XREF=gi:4506248 /UG=Hs.10712 phosphatase and tensin homolog (mutated in multiple advanced cancers 1) /FL=gb:U92436.1 gb:U93051.1 gb:U96180.1 gb:NM_000314.1" NM_000314 phosphatase and tensin homolog PTEN 5728 NM_000314 /// XM_006717926 /// XM_006717927 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0002902 // regulation of B cell apoptotic process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from direct assay /// 0006470 // protein dephosphorylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007092 // activation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007270 // neuron-neuron synaptic transmission // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0007613 // memory // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010043 // response to zinc ion // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from sequence or structural similarity /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0021542 // dentate gyrus development // inferred from sequence or structural similarity /// 0021955 // central nervous system neuron axonogenesis // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0031175 // neuron projection development // inferred from electronic annotation /// 0031642 // negative regulation of myelination // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0031658 // negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle // inferred from direct assay /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032535 // regulation of cellular component size // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033198 // response to ATP // inferred from electronic annotation /// 0033555 // multicellular organismal response to stress // inferred from sequence or structural similarity /// 0035176 // social behavior // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045475 // locomotor rhythm // inferred from sequence or structural similarity /// 0045792 // negative regulation of cell size // inferred from sequence or structural similarity /// 0046621 // negative regulation of organ growth // inferred from sequence or structural similarity /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0046856 // phosphatidylinositol dephosphorylation // inferred from mutant phenotype /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from direct assay /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype /// 0051898 // negative regulation of protein kinase B signaling // inferred from mutant phenotype /// 0060024 // rhythmic synaptic transmission // inferred from sequence or structural similarity /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060074 // synapse maturation // inferred from sequence or structural similarity /// 0060134 // prepulse inhibition // inferred from sequence or structural similarity /// 0060179 // male mating behavior // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060292 // long term synaptic depression // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0090071 // negative regulation of ribosome biogenesis // inferred from electronic annotation /// 0090344 // negative regulation of cell aging // inferred from electronic annotation /// 0090394 // negative regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 0097107 // postsynaptic density assembly // inferred from sequence or structural similarity /// 2000060 // positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity /// 2000808 // negative regulation of synaptic vesicle clustering // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0035749 // myelin sheath adaxonal region // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from direct assay /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043220 // Schmidt-Lanterman incisure // inferred from sequence or structural similarity /// 0045211 // postsynaptic membrane // inferred from electronic annotation "0000287 // magnesium ion binding // inferred from electronic annotation /// 0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004722 // protein serine/threonine phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0010997 // anaphase-promoting complex binding // inferred from physical interaction /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // inferred from direct assay /// 0016314 // phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // inferred from direct assay /// 0051717 // inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity // traceable author statement /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // inferred from direct assay /// 0051800 // phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity // traceable author statement" 204055_s_at NM_005930 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005930.1 /DEF=Homo sapiens meningioma expressed antigen 6 (coiled-coil proline-rich) (MGEA6), mRNA. /FEA=mRNA /GEN=MGEA6 /PROD=meningioma expressed antigen 6 (coiled-coilproline-rich) /DB_XREF=gi:5174560 /UG=Hs.117242 meningioma expressed antigen 6 (coiled-coil proline-rich) /FL=gb:U94780.1 gb:NM_005930.1" NM_005930 "CTAGE family, member 5" CTAGE5 4253 NM_001247988 /// NM_001247989 /// NM_001247990 /// NM_005930 /// NM_203354 /// NM_203355 /// NM_203356 /// NM_203357 /// XM_005267646 /// XM_005267647 /// XM_005267648 /// XM_005267649 /// XM_005267650 /// XM_006720148 0043085 // positive regulation of catalytic activity // traceable author statement 0016020 // membrane // inferred from direct assay 0008047 // enzyme activator activity // traceable author statement 204056_s_at NM_000431 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000431.1 /DEF=Homo sapiens mevalonate kinase (mevalonic aciduria) (MVK), mRNA. /FEA=mRNA /GEN=MVK /PROD=mevalonate kinase /DB_XREF=gi:4557768 /UG=Hs.130607 mevalonate kinase (mevalonic aciduria) /FL=gb:M88468.1 gb:NM_000431.1" NM_000431 mevalonate kinase MVK 4598 NM_000431 /// NM_001114185 /// XM_005253883 /// XM_005253884 "0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from direct assay /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from direct assay /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019287 // isopentenyl diphosphate biosynthetic process, mevalonate pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0050728 // negative regulation of inflammatory response // inferred from mutant phenotype" 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004496 // mevalonate kinase activity // inferred from direct assay /// 0004496 // mevalonate kinase activity // inferred from mutant phenotype /// 0004496 // mevalonate kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction" 204057_at AI073984 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI073984 /FEA=EST /DB_XREF=gi:3400628 /DB_XREF=est:oy66c05.x1 /CLONE=IMAGE:1670792 /UG=Hs.14453 interferon consensus sequence binding protein 1 /FL=gb:M91196.1 gb:NM_002163.1 AI073984 interferon regulatory factor 8 IRF8 3394 NM_002163 /// XM_006721187 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000975 // regulatory region DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204058_at AL049699 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL049699 /DEF=Human DNA sequence from clone 747H23 on chromosome 6q13-15. Contains the 3 part of the ME1 gene for malic enzyme 1, soluble (NADP-dependent malic enzyme, malate oxidoreductase, EC 1.1.1.40), a novel gene and the 5 part of the gene for N-acetylgl... /FEA=mRNA_3 /DB_XREF=gi:5419832 /UG=Hs.14732 malic enzyme 1, NADP(+)-dependent, cytosolic /FL=gb:NM_002395.2" AL049699 "malic enzyme 1, NADP(+)-dependent, cytosolic" ME1 4199 NM_002395 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006108 // malate metabolic process // inferred from direct assay /// 0006741 // NADP biosynthetic process // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement "0004470 // malic enzyme activity // inferred from direct assay /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from direct assay /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from sequence or structural similarity /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043531 // ADP binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement /// 0051287 // NAD binding // traceable author statement" 204059_s_at NM_002395 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002395.2 /DEF=Homo sapiens malic enzyme 1, NADP(+)-dependent, cytosolic (ME1), mRNA. /FEA=mRNA /GEN=ME1 /PROD=cytosolic malic enzyme 1 /DB_XREF=gi:13435400 /UG=Hs.14732 malic enzyme 1, NADP(+)-dependent, cytosolic /FL=gb:NM_002395.2" NM_002395 "malic enzyme 1, NADP(+)-dependent, cytosolic" ME1 4199 NM_002395 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006108 // malate metabolic process // inferred from direct assay /// 0006741 // NADP biosynthetic process // traceable author statement /// 0009725 // response to hormone // inferred from sequence or structural similarity /// 0009743 // response to carbohydrate // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051262 // protein tetramerization // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement "0004470 // malic enzyme activity // inferred from direct assay /// 0004471 // malate dehydrogenase (decarboxylating) (NAD+) activity // inferred from electronic annotation /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from direct assay /// 0004473 // malate dehydrogenase (decarboxylating) (NADP+) activity // inferred from sequence or structural similarity /// 0008948 // oxaloacetate decarboxylase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay /// 0043531 // ADP binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // traceable author statement /// 0051287 // NAD binding // traceable author statement" 204060_s_at NM_005044 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005044.1 /DEF=Homo sapiens protein kinase, X-linked (PRKX), mRNA. /FEA=mRNA /GEN=PRKX /PROD=protein kinase, X-linked /DB_XREF=gi:4826947 /UG=Hs.147996 protein kinase, X-linked /FL=gb:NM_005044.1" NM_005044 "protein kinase, X-linked /// protein kinase, Y-linked, pseudogene" PRKX /// PRKY 5613 /// 5616 NM_002760 /// NM_005044 /// NR_028062 /// XM_005274560 /// XM_005274561 0001525 // angiogenesis // inferred from mutant phenotype /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030334 // regulation of cell migration // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060562 // epithelial tube morphogenesis // inferred from direct assay /// 0060993 // kidney morphogenesis // inferred from direct assay /// 2000696 // regulation of epithelial cell differentiation involved in kidney development // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction" 204061_at NM_005044 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005044.1 /DEF=Homo sapiens protein kinase, X-linked (PRKX), mRNA. /FEA=mRNA /GEN=PRKX /PROD=protein kinase, X-linked /DB_XREF=gi:4826947 /UG=Hs.147996 protein kinase, X-linked /FL=gb:NM_005044.1" NM_005044 "protein kinase, X-linked" PRKX 5613 NM_005044 /// XM_005274560 /// XM_005274561 0001525 // angiogenesis // inferred from mutant phenotype /// 0001935 // endothelial cell proliferation // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030155 // regulation of cell adhesion // inferred from direct assay /// 0030334 // regulation of cell migration // inferred from direct assay /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060562 // epithelial tube morphogenesis // inferred from direct assay /// 0060993 // kidney morphogenesis // inferred from direct assay /// 2000696 // regulation of epithelial cell differentiation involved in kidney development // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004691 // cAMP-dependent protein kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction" 204062_s_at BG526973 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG526973 /FEA=EST /DB_XREF=gi:13518510 /DB_XREF=est:602556210F1 /CLONE=IMAGE:4685114 /UG=Hs.151406 KIAA0623 gene product /FL=gb:AB014523.1 gb:NM_014683.1 BG526973 unc-51 like autophagy activating kinase 2 ULK2 9706 NM_001142610 /// NM_014683 /// XM_006721606 0000045 // autophagic vacuole assembly // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048671 // negative regulation of collateral sprouting // inferred from electronic annotation /// 0048675 // axon extension // not recorded 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0034273 // Atg1p signaling complex // not recorded "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 204063_s_at NM_014683 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014683.1 /DEF=Homo sapiens KIAA0623 gene product (KIAA0623), mRNA. /FEA=mRNA /GEN=KIAA0623 /PROD=KIAA0623 gene product /DB_XREF=gi:7662209 /UG=Hs.151406 KIAA0623 gene product /FL=gb:AB014523.1 gb:NM_014683.1" NM_014683 unc-51 like autophagy activating kinase 2 ULK2 9706 NM_001142610 /// NM_014683 /// XM_006721606 0000045 // autophagic vacuole assembly // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042594 // response to starvation // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048671 // negative regulation of collateral sprouting // inferred from electronic annotation /// 0048675 // axon extension // not recorded 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034045 // pre-autophagosomal structure membrane // inferred from direct assay /// 0034273 // Atg1p signaling complex // not recorded "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 204064_at NM_005131 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005131.1 /DEF=Homo sapiens nuclear matrix protein p84 (P84), mRNA. /FEA=mRNA /GEN=P84 /PROD=nuclear matrix protein p84 /DB_XREF=gi:4826881 /UG=Hs.1540 nuclear matrix protein p84 /FL=gb:NM_005131.1 gb:L36529.1" NM_005131 THO complex 1 THOC1 9984 NM_005131 "0000018 // regulation of DNA recombination // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0031297 // replication fork processing // inferred from mutant phenotype /// 0032784 // regulation of DNA-templated transcription, elongation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0048297 // negative regulation of isotype switching to IgA isotypes // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype" 0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0045171 // intercellular bridge // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204065_at NM_004854 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004854.1 /DEF=Homo sapiens HNK-1 sulfotransferase (HNK-1ST), mRNA. /FEA=mRNA /GEN=HNK-1ST /PROD=HNK-1 sulfotransferase /DB_XREF=gi:4758539 /UG=Hs.155553 HNK-1 sulfotransferase /FL=gb:AF033827.1 gb:AF070594.1 gb:NM_004854.1" NM_004854 carbohydrate sulfotransferase 10 CHST10 9486 NM_004854 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007612 // learning // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0016051 // carbohydrate biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // traceable author statement /// 0016232 // HNK-1 sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204066_s_at NM_014914 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014914.1 /DEF=Homo sapiens KIAA1099 protein (KIAA1099), mRNA. /FEA=mRNA /GEN=KIAA1099 /PROD=KIAA1099 protein /DB_XREF=gi:7662483 /UG=Hs.159377 KIAA1099 protein /FL=gb:AB029022.1 gb:NM_014914.1" NM_014914 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 1" AGAP1 116987 NM_001037131 /// NM_001244888 /// NM_014914 /// XM_005246058 /// XM_005246059 /// XM_006712234 /// XM_006712235 /// XM_006712236 /// XM_006712237 /// XM_006712238 /// XM_006712239 /// XM_006712240 /// XM_006712241 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from direct assay /// 0008060 // ARF GTPase activator activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204067_at AA129776 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA129776 /FEA=EST /DB_XREF=gi:1690187 /DB_XREF=est:zl16h11.s1 /CLONE=IMAGE:502149 /UG=Hs.16340 sulfite oxidase /FL=gb:NM_000456.1 gb:L31573.1 AA129776 sulfite oxidase SUOX 6821 NM_000456 /// NM_001032386 /// NM_001032387 /// XM_005269112 "0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006790 // sulfur compound metabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0070221 // sulfide oxidation, using sulfide:quinone oxidoreductase // traceable author statement" 0005739 // mitochondrion // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0008482 // sulfite oxidase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0030151 // molybdenum ion binding // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204068_at NM_006281 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006281.1 /DEF=Homo sapiens serinethreonine kinase 3 (Ste20, yeast homolog) (STK3), mRNA. /FEA=mRNA /GEN=STK3 /PROD=serinethreonine kinase 3 (Ste20, yeasthomolog) /DB_XREF=gi:5454093 /UG=Hs.166684 serinethreonine kinase 3 (Ste20, yeast homolog) /FL=gb:U26424.1 gb:U60206.1 gb:NM_006281.1" NM_006281 serine/threonine kinase 3 STK3 6788 NM_001256312 /// NM_001256313 /// NM_006281 /// XM_005251034 0001841 // neural tube formation // inferred from electronic annotation /// 0003157 // endocardium development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // not recorded /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0046621 // negative regulation of organ growth // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0060215 // primitive hemopoiesis // inferred from electronic annotation /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation /// 0071902 // positive regulation of protein serine/threonine kinase activity // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097284 // hepatocyte apoptotic process // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0043539 // protein serine/threonine kinase activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from sequence or structural similarity" 204069_at NM_002398 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002398.1 /DEF=Homo sapiens Meis1 (mouse) homolog (MEIS1), mRNA. /FEA=mRNA /GEN=MEIS1 /PROD=Meis1 homolog /DB_XREF=gi:4505150 /UG=Hs.170177 Meis1 (mouse) homolog /FL=gb:U85707.1 gb:NM_002398.1" NM_002398 Meis homeobox 1 MEIS1 4211 NM_002398 /// XM_005264321 /// XM_005264322 /// XM_005264323 /// XM_005264324 /// XM_005264325 /// XM_006712020 /// XR_244932 /// XR_244933 "0001525 // angiogenesis // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from sequence or structural similarity /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0060216 // definitive hemopoiesis // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204070_at NM_004585 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004585.2 /DEF=Homo sapiens retinoic acid receptor responder (tazarotene induced) 3 (RARRES3), mRNA. /FEA=mRNA /GEN=RARRES3 /PROD=retinoic acid receptor responder (tazaroteneinduced) 3 /DB_XREF=gi:8051633 /UG=Hs.17466 retinoic acid receptor responder (tazarotene induced) 3 /FL=gb:AF060228.1 gb:AF092922.1 gb:NM_004585.2 gb:AB030815.1" NM_004585 retinoic acid receptor responder (tazarotene induced) 3 RARRES3 5920 NM_004585 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 204071_s_at NM_005802 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005802.1 /DEF=Homo sapiens tumor protein p53-binding protein (TP53BPL), mRNA. /FEA=mRNA /GEN=TP53BPL /PROD=tumor protein p53-binding protein /DB_XREF=gi:5032190 /UG=Hs.179982 tumor protein p53-binding protein /FL=gb:U82939.1 gb:AF098300.1 gb:NM_005802.1 gb:AB045732.1" NM_005802 "topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase" TOPORS 10210 NM_001195622 /// NM_005802 "0006351 // transcription, DNA-templated // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0006513 // protein monoubiquitination // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0016925 // protein sumoylation // inferred from direct assay /// 0016925 // protein sumoylation // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from mutant phenotype /// 0035845 // photoreceptor cell outer segment organization // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046548 // retinal rod cell development // inferred from sequence or structural similarity /// 0046549 // retinal cone cell development // inferred from sequence or structural similarity /// 0051443 // positive regulation of ubiquitin-protein transferase activity // inferred from direct assay /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay" 0000151 // ubiquitin ligase complex // inferred from direct assay /// 0000922 // spindle pole // inferred from direct assay /// 0000930 // gamma-tubulin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005868 // cytoplasmic dynein complex // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0032391 // photoreceptor connecting cilium // inferred from direct assay /// 0036064 // ciliary basal body // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003823 // antigen binding // inferred from physical interaction /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019789 // SUMO ligase activity // inferred from direct assay /// 0019789 // SUMO ligase activity // inferred from mutant phenotype /// 0044547 // DNA topoisomerase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204072_s_at NM_023037 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_023037.1 /DEF=Homo sapiens putative gene product (13CDNA73), mRNA. /FEA=mRNA /GEN=13CDNA73 /PROD=putative gene product /DB_XREF=gi:12957487 /UG=Hs.181304 putative gene product /FL=gb:NM_023037.1" NM_023037 furry homolog (Drosophila) FRY 10129 NM_023037 /// XM_006719749 0000922 // spindle pole // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation 204073_s_at NM_013279 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013279.1 /DEF=Homo sapiens chromosome 11open reading frame 9 (C11ORF9), mRNA. /FEA=mRNA /GEN=C11ORF9 /PROD=chromosome 11open reading frame 9 /DB_XREF=gi:7019334 /UG=Hs.184640 chromosome 11open reading frame 9 /FL=gb:BC004938.1 gb:AF086762.1 gb:NM_013279.1" NM_013279 myelin regulatory factor MYRF 745 NM_001127392 /// NM_013279 /// XM_005274222 /// XM_005274223 /// XM_005274224 /// XM_005274225 /// XM_005274226 /// XM_005274227 /// XM_005274228 /// XM_005274229 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from sequence or structural similarity /// 0022010 // central nervous system myelination // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031643 // positive regulation of myelination // inferred from sequence or structural similarity /// 0032286 // central nervous system myelin maintenance // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048709 // oligodendrocyte differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204074_s_at AI936976 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI936976 /FEA=EST /DB_XREF=gi:5675846 /DB_XREF=est:wp71f07.x1 /CLONE=IMAGE:2467237 /UG=Hs.200595 KIAA0562 gene product /FL=gb:AB011134.1 gb:NM_014704.1 AI936976 centrosomal protein 104kDa CEP104 9731 NM_014704 /// XM_005244815 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0016594 // glycine binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016596 // thienylcyclohexylpiperidine binding // inferred from electronic annotation 204075_s_at NM_014704 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014704.1 /DEF=Homo sapiens KIAA0562 gene product (KIAA0562), mRNA. /FEA=mRNA /GEN=KIAA0562 /PROD=KIAA0562 gene product /DB_XREF=gi:7662179 /UG=Hs.200595 KIAA0562 gene product /FL=gb:AB011134.1 gb:NM_014704.1" NM_014704 centrosomal protein 104kDa CEP104 9731 NM_014704 /// XM_005244815 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0016594 // glycine binding // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0016596 // thienylcyclohexylpiperidine binding // inferred from electronic annotation 204076_at AB002390 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB002390.1 /DEF=Human mRNA for KIAA0392 gene, partial cds. /FEA=mRNA /GEN=KIAA0392 /DB_XREF=gi:2280487 /UG=Hs.201377 apyrase, lysosomal /FL=gb:AF016032.1 gb:NM_004901.1" AB002390 ectonucleoside triphosphate diphosphohydrolase 4 ENTPD4 9583 NM_001128930 /// NM_004901 0006256 // UDP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from direct assay 204077_x_at NM_004901 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004901.1 /DEF=Homo sapiens apyrase, lysosomal (LAP70), mRNA. /FEA=mRNA /GEN=LAP70 /PROD=apyrase, lysosomal /DB_XREF=gi:4758661 /UG=Hs.201377 apyrase, lysosomal /FL=gb:AF016032.1 gb:NM_004901.1" NM_004901 ectonucleoside triphosphate diphosphohydrolase 4 ENTPD4 9583 NM_001128930 /// NM_004901 0006256 // UDP catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000421 // autophagic vacuole membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0045134 // uridine-diphosphatase activity // inferred from direct assay 204078_at NM_006455 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006455.1 /DEF=Homo sapiens nucleolar autoantigen (55kD) similar to rat synaptonemal complex protein (SC65), mRNA. /FEA=mRNA /GEN=SC65 /PROD=nucleolar autoantigen (55kD) similar to ratsynaptonemal complex protein /DB_XREF=gi:5454037 /UG=Hs.207251 nucleolar autoantigen (55kD) similar to rat synaptonemal complex protein /FL=gb:BC001047.1 gb:U47621.1 gb:NM_006455.1" NM_006455 leprecan-like 4 LEPREL4 10609 NM_006455 /// XM_005256952 /// XM_005256953 /// XM_006721640 0007130 // synaptonemal complex assembly // traceable author statement 0000794 // condensed nuclear chromosome // traceable author statement /// 0000795 // synaptonemal complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation 204079_at NM_003595 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003595.1 /DEF=Homo sapiens tyrosylprotein sulfotransferase 2 (TPST2), mRNA. /FEA=mRNA /GEN=TPST2 /PROD=tyrosylprotein sulfotransferase 2 /DB_XREF=gi:4507666 /UG=Hs.26350 tyrosylprotein sulfotransferase 2 /FL=gb:AL136623.1 gb:BC001057.1 gb:AF061254.1 gb:AF049891.1 gb:NM_003595.1" NM_003595 tyrosylprotein sulfotransferase 2 TPST2 8459 NM_001008566 /// NM_003595 /// XM_006724338 0006478 // peptidyl-tyrosine sulfation // inferred from electronic annotation /// 0007342 // fusion of sperm to egg plasma membrane // inferred from electronic annotation /// 0060468 // prevention of polyspermy // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008476 // protein-tyrosine sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204080_at NM_025077 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_025077.1 /DEF=Homo sapiens hypothetical protein FLJ13949 (FLJ13949), mRNA. /FEA=mRNA /GEN=FLJ13949 /PROD=hypothetical protein FLJ13949 /DB_XREF=gi:13376627 /UG=Hs.288198 hypothetical protein FLJ13949 /FL=gb:NM_025077.1" NM_025077 "target of EGR1, member 1 (nuclear)" TOE1 114034 NM_025077 /// XM_005270412 /// XM_005270413 /// XR_246230 /// XR_426587 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204081_at NM_006176 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006176.1 /DEF=Homo sapiens neurogranin (protein kinase C substrate, RC3) (NRGN), mRNA. /FEA=mRNA /GEN=NRGN /PROD=neurogranin /DB_XREF=gi:5453799 /UG=Hs.26944 neurogranin (protein kinase C substrate, RC3) /FL=gb:BC002835.1 gb:U89165.1 gb:NM_006176.1" NM_006176 "neurogranin (protein kinase C substrate, RC3)" NRGN 4900 NM_001126181 /// NM_006176 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 204082_at NM_006195 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006195.1 /DEF=Homo sapiens pre-B-cell leukemia transcription factor 3 (PBX3), mRNA. /FEA=mRNA /GEN=PBX3 /PROD=pre-B-cell leukemia transcription factor 3 /DB_XREF=gi:5453851 /UG=Hs.294101 pre-B-cell leukemia transcription factor 3 /FL=gb:NM_006195.1" NM_006195 pre-B-cell leukemia homeobox 3 PBX3 5090 NM_001134778 /// NM_006195 /// NR_024122 /// NR_024123 /// XM_006717130 /// XM_006717131 /// XM_006717132 /// XM_006717133 "0002087 // regulation of respiratory gaseous exchange by neurological system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007387 // anterior compartment pattern formation // traceable author statement /// 0007388 // posterior compartment specification // traceable author statement /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0021516 // dorsal spinal cord development // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204083_s_at NM_003289 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003289.1 /DEF=Homo sapiens tropomyosin 2 (beta) (TPM2), mRNA. /FEA=mRNA /GEN=TPM2 /PROD=tropomyosin 2 (beta) /DB_XREF=gi:4507648 /UG=Hs.300772 tropomyosin 2 (beta) /FL=gb:M75165.1 gb:M12125.1 gb:M74817.1 gb:NM_003289.1" NM_003289 tropomyosin 2 (beta) TPM2 7169 NM_001145822 /// NM_003289 /// NM_213674 /// XM_005251566 /// XM_005251567 /// XM_005251568 /// XM_005251569 /// XM_005251570 /// XM_005251571 /// XM_005251572 0006936 // muscle contraction // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement /// 0043462 // regulation of ATPase activity // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005862 // muscle thin filament tropomyosin // traceable author statement 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement 204084_s_at AI911687 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI911687 /FEA=EST /DB_XREF=gi:5631542 /DB_XREF=est:wc71g01.x1 /CLONE=IMAGE:2324112 /UG=Hs.30213 ceroid-lipofuscinosis, neuronal 5 /FL=gb:AF068227.1 gb:NM_006493.1" AI911687 "ceroid-lipofuscinosis, neuronal 5" CLN5 1203 NM_006493 0006465 // signal peptide processing // inferred from direct assay /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007420 // brain development // inferred from expression pattern /// 0007601 // visual perception // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from expression pattern /// 0030163 // protein catabolic process // non-traceable author statement /// 0042551 // neuron maturation // non-traceable author statement /// 0070085 // glycosylation // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005775 // vacuolar lumen // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from direct assay 204085_s_at NM_006493 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006493.1 /DEF=Homo sapiens ceroid-lipofuscinosis, neuronal 5 (CLN5), mRNA. /FEA=mRNA /GEN=CLN5 /PROD=ceroid-lipofuscinosis, neuronal 5 /DB_XREF=gi:5729771 /UG=Hs.30213 ceroid-lipofuscinosis, neuronal 5 /FL=gb:AF068227.1 gb:NM_006493.1" NM_006493 "ceroid-lipofuscinosis, neuronal 5" CLN5 1203 NM_006493 0006465 // signal peptide processing // inferred from direct assay /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007420 // brain development // inferred from expression pattern /// 0007601 // visual perception // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from expression pattern /// 0030163 // protein catabolic process // non-traceable author statement /// 0042551 // neuron maturation // non-traceable author statement /// 0070085 // glycosylation // inferred from direct assay 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005775 // vacuolar lumen // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005537 // mannose binding // inferred from direct assay 204086_at NM_006115 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006115.1 /DEF=Homo sapiens preferentially expressed antigen in melanoma (PRAME), mRNA. /FEA=mRNA /GEN=PRAME /PROD=preferentially expressed antigen of melanoma /DB_XREF=gi:5174640 /UG=Hs.30743 preferentially expressed antigen in melanoma /FL=gb:U65011.1 gb:NM_006115.1" NM_006115 preferentially expressed antigen in melanoma PRAME 23532 NM_001291715 /// NM_001291716 /// NM_001291717 /// NM_001291719 /// NM_006115 /// NM_206953 /// NM_206954 /// NM_206955 /// NM_206956 /// XM_006725402 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0045596 // negative regulation of cell differentiation // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042974 // retinoic acid receptor binding // inferred from direct assay 204087_s_at NM_021095 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021095.1 /DEF=Homo sapiens solute carrier family 5 (sodium-dependent vitamin transporter), member 6 (SLC5A6), mRNA. /FEA=mRNA /GEN=SLC5A6 /PROD=solute carrier family 5 (sodium-dependentvitamin transporter), member 6 /DB_XREF=gi:10863878 /UG=Hs.321579 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 /FL=gb:NM_021095.1 gb:AF069307.1 gb:AF081571.1" NM_021095 "solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6" SLC5A6 8884 NM_021095 /// NR_028323 /// XM_006712128 /// XM_006712129 /// XM_006712130 /// XM_006712131 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0015878 // biotin transport // inferred from electronic annotation /// 0015887 // pantothenate transmembrane transport // inferred from electronic annotation /// 0015939 // pantothenate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0012506 // vesicle membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0008523 // sodium-dependent multivitamin transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation 204088_at NM_002560 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002560.1 /DEF=Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), mRNA. /FEA=mRNA /GEN=P2RX4 /PROD=purinergic receptor P2X, ligand-gated ionchannel, 4 /DB_XREF=gi:4505548 /UG=Hs.321709 purinergic receptor P2X, ligand-gated ion channel, 4 /FL=gb:U83993.1 gb:NM_002560.1" NM_002560 "purinergic receptor P2X, ligand-gated ion channel, 4" P2RX4 5025 NM_001256796 /// NM_001261397 /// NM_001261398 /// NM_002560 /// NM_175567 /// NM_175568 /// NR_046372 /// NR_046373 /// XR_429105 0001894 // tissue homeostasis // non-traceable author statement /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from direct assay /// 0006811 // ion transport // inferred from electronic annotation /// 0006812 // cation transport // inferred from direct assay /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from direct assay /// 0010524 // positive regulation of calcium ion transport into cytosol // inferred from mutant phenotype /// 0010614 // negative regulation of cardiac muscle hypertrophy // inferred from mutant phenotype /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from sequence or structural similarity /// 0032308 // positive regulation of prostaglandin secretion // non-traceable author statement /// 0033198 // response to ATP // inferred from direct assay /// 0034220 // ion transmembrane transport // inferred from direct assay /// 0034405 // response to fluid shear stress // inferred from direct assay /// 0035590 // purinergic nucleotide receptor signaling pathway // inferred from mutant phenotype /// 0042118 // endothelial cell activation // traceable author statement /// 0042311 // vasodilation // inferred from electronic annotation /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050850 // positive regulation of calcium-mediated signaling // inferred from direct assay /// 0050850 // positive regulation of calcium-mediated signaling // inferred from mutant phenotype /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // non-traceable author statement /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0055119 // relaxation of cardiac muscle // inferred from mutant phenotype /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0071318 // cellular response to ATP // inferred from direct assay /// 0097190 // apoptotic signaling pathway // inferred from direct assay 0005639 // integral component of nuclear inner membrane // not recorded /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred by curator /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043195 // terminal bouton // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001614 // purinergic nucleotide receptor activity // inferred from direct assay /// 0001614 // purinergic nucleotide receptor activity // inferred from mutant phenotype /// 0004931 // extracellular ATP-gated cation channel activity // inferred from direct assay /// 0005102 // receptor binding // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred by curator /// 0008144 // drug binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0045296 // cadherin binding // inferred from physical interaction 204089_x_at NM_006724 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006724.1 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 4 (MAP3K4), transcript variant 2, mRNA. /FEA=mRNA /GEN=MAP3K4 /PROD=MAPERK kinase kinase 4, isoform b /DB_XREF=gi:6031179 /UG=Hs.32353 mitogen-activated protein kinase kinase kinase 4 /FL=gb:NM_006724.1 gb:AF116604.1" NM_006724 mitogen-activated protein kinase kinase kinase 4 MAP3K4 4216 NM_001291958 /// NM_005922 /// NM_006724 /// NR_120425 /// XM_005266988 /// XM_005266989 /// XR_245517 0000165 // MAPK cascade // inferred from direct assay /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0010225 // response to UV-C // inferred from mutant phenotype /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019100 // male germ-line sex determination // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043507 // positive regulation of JUN kinase activity // inferred from direct assay /// 0060718 // chorionic trophoblast cell differentiation // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004709 // MAP kinase kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204090_at NM_004197 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004197.1 /DEF=Homo sapiens serinethreonine kinase 19 (STK19), mRNA. /FEA=mRNA /GEN=STK19 /PROD=serinethreonine kinase 19 /DB_XREF=gi:4759179 /UG=Hs.444 serinethreonine kinase 19 /FL=gb:L26260.1 gb:NM_004197.1" NM_004197 serine/threonine kinase 19 STK19 8859 NM_004197 /// NM_032454 /// NR_026717 0006468 // protein phosphorylation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204091_at NM_002601 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002601.1 /DEF=Homo sapiens phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mRNA. /FEA=mRNA /GEN=PDE6D /PROD=phosphodiesterase 6D, cGMP-specific, rod, delta /DB_XREF=gi:4505670 /UG=Hs.48291 phosphodiesterase 6D, cGMP-specific, rod, delta /FL=gb:AF022912.1 gb:NM_002601.1" NM_002601 "phosphodiesterase 6D, cGMP-specific, rod, delta" PDE6D 5147 NM_001291018 /// NM_002601 /// NR_110994 0007601 // visual perception // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033124 // regulation of GTP catabolic process // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from sequence or structural similarity /// 0050896 // response to stimulus // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from direct assay "0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from physical interaction" 204092_s_at NM_003600 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003600.1 /DEF=Homo sapiens serinethreonine kinase 15 (STK15), mRNA. /FEA=mRNA /GEN=STK15 /PROD=serinethreonine kinase 15 /DB_XREF=gi:4507274 /UG=Hs.48915 serinethreonine kinase 15 /FL=gb:AF008551.1 gb:AF011468.1 gb:NM_003600.1" NM_003600 aurora kinase A AURKA 6790 NM_003600 /// NM_198433 /// NM_198434 /// NM_198435 /// NM_198436 /// NM_198437 /// XM_005260534 /// XM_006723871 /// XM_006723872 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0043146 // spindle stabilization // inferred from mutant phenotype /// 0045840 // positive regulation of mitosis // traceable author statement /// 0046605 // regulation of centrosome cycle // traceable author statement /// 0046777 // protein autophosphorylation // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030496 // midbody // traceable author statement /// 0031616 // spindle pole centrosome // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004712 // protein serine/threonine/tyrosine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation" 204093_at NM_001239 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001239.1 /DEF=Homo sapiens cyclin H (CCNH), mRNA. /FEA=mRNA /GEN=CCNH /PROD=cyclin H /DB_XREF=gi:4502622 /UG=Hs.514 cyclin H /FL=gb:BC005280.1 gb:NM_001239.1 gb:U12685.1 gb:U11791.1" NM_001239 cyclin H CCNH 902 NM_001199189 /// NM_001239 /// XM_005248627 /// XM_005248629 /// XR_427721 "0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006362 // transcription elongation from RNA polymerase I promoter // traceable author statement /// 0006363 // termination of RNA polymerase I transcription // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0050434 // positive regulation of viral transcription // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation" "0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005675 // holo TFIIH complex // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0016591 // DNA-directed RNA polymerase II, holoenzyme // inferred from electronic annotation /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0070985 // TFIIK complex // inferred from electronic annotation" 0005515 // protein binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008353 // RNA polymerase II carboxy-terminal domain kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation 204094_s_at NM_014779 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014779.1 /DEF=Homo sapiens KIAA0669 gene product (KIAA0669), mRNA. /FEA=mRNA /GEN=KIAA0669 /PROD=KIAA0669 gene product /DB_XREF=gi:7662235 /UG=Hs.52526 KIAA0669 gene product /FL=gb:AB014569.1 gb:NM_014779.1" NM_014779 "TSC22 domain family, member 2" TSC22D2 9819 NM_014779 /// XM_005247920 /// XR_427388 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006970 // response to osmotic stress // inferred from electronic annotation" 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation 204095_s_at AL521391 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL521391 /FEA=EST /DB_XREF=gi:12784884 /DB_XREF=est:AL521391 /CLONE=CS0DB001YB07 (3 prime) /UG=Hs.5881 ELL gene (11-19 lysine-rich leukemia gene) /FL=gb:AL136771.1 gb:NM_006532.1 gb:U16282.1 AL521391 elongation factor RNA polymerase II ELL 8178 NM_006532 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0008023 // transcription elongation factor complex // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 204096_s_at AL136771 Homo sapiens 6-Oct-14 Exemplar sequence GenBank gb:AL136771.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434I1916 (from clone DKFZp434I1916); complete cds. /FEA=mRNA /GEN=DKFZp434I1916 /PROD=hypothetical protein /DB_XREF=gi:12053058 /UG=Hs.5881 ELL gene (11-19 lysine-rich leukemia gene) /FL=gb:AL136771.1 gb:NM_006532.1 gb:U16282.1 AL136771 elongation factor RNA polymerase II ELL 8178 NM_006532 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0032786 // positive regulation of DNA-templated transcription, elongation // traceable author statement /// 0050434 // positive regulation of viral transcription // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0008023 // transcription elongation factor complex // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019902 // phosphatase binding // inferred from direct assay 204097_s_at AF078865 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF078865.1 /DEF=Homo sapiens RNA-binding protein mRNA, complete cds. /FEA=mRNA /PROD=RNA-binding protein /DB_XREF=gi:5531844 /UG=Hs.61184 CGI-79 protein /FL=gb:AF151837.1 gb:AF078865.1 gb:NM_016024.1" AF078865 "RNA binding motif protein, X-linked 2" RBMX2 51634 NM_016024 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204098_at NM_016024 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016024.1 /DEF=Homo sapiens CGI-79 protein (LOC51634), mRNA. /FEA=mRNA /GEN=LOC51634 /PROD=CGI-79 protein /DB_XREF=gi:7706315 /UG=Hs.61184 CGI-79 protein /FL=gb:AF151837.1 gb:AF078865.1 gb:NM_016024.1" NM_016024 "RNA binding motif protein, X-linked 2" RBMX2 51634 NM_016024 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204099_at NM_003078 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003078.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 (SMARCD3), mRNA. /FEA=mRNA /GEN=SMARCD3 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily d, member 3 /DB_XREF=gi:4507086 /UG=Hs.71622 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 /FL=gb:BC002628.1 gb:U66619.1 gb:NM_003078.1" NM_003078 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" SMARCD3 6604 NM_001003801 /// NM_001003802 /// NM_003078 "0002052 // positive regulation of neuroblast proliferation // inferred from direct assay /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0003139 // secondary heart field specification // inferred from electronic annotation /// 0003219 // cardiac right ventricle formation // inferred from electronic annotation /// 0003407 // neural retina development // inferred from expression pattern /// 0006337 // nucleosome disassembly // inferred from direct assay /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0016514 // SWI/SNF complex // non-traceable author statement /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity /// 0071565 // nBAF complex // inferred from sequence or structural similarity 0003713 // transcription coactivator activity // non-traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from mutant phenotype /// 0035257 // nuclear hormone receptor binding // inferred from physical interaction 204100_at NM_003250 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003250.1 /DEF=Homo sapiens thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog) (THRA), mRNA. /FEA=mRNA /GEN=THRA /PROD=thyroid hormone receptor, alpha (avianerythroblastic leukemia viral (v-erb-a) oncogene homolog) /DB_XREF=gi:4507494 /UG=Hs.724 thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog) /FL=gb:BC000261.1 gb:BC002728.1 gb:NM_003250.1 gb:J03239.1 gb:M24899.1" NM_003250 "thyroid hormone receptor, alpha" THRA 7067 NM_001190918 /// NM_001190919 /// NM_003250 /// NM_199334 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0002155 // regulation of thyroid hormone mediated signaling pathway // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0008050 // female courtship behavior // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010498 // proteasomal protein catabolic process // inferred from sequence or structural similarity /// 0010831 // positive regulation of myotube differentiation // inferred from electronic annotation /// 0010871 // negative regulation of receptor biosynthetic process // inferred from mutant phenotype /// 0017055 // negative regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from direct assay /// 0019216 // regulation of lipid metabolic process // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0033032 // regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0034144 // negative regulation of toll-like receptor 4 signaling pathway // inferred from mutant phenotype /// 0035947 // regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044321 // response to leptin // inferred from sequence or structural similarity /// 0045598 // regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045925 // positive regulation of female receptivity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050994 // regulation of lipid catabolic process // inferred from electronic annotation /// 0060086 // circadian temperature homeostasis // inferred from sequence or structural similarity /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0061178 // regulation of insulin secretion involved in cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0061469 // regulation of type B pancreatic cell proliferation // inferred from sequence or structural similarity /// 0070859 // positive regulation of bile acid biosynthetic process // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from mutant phenotype /// 2000143 // negative regulation of DNA-templated transcription, initiation // inferred from direct assay /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay" 0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from mutant phenotype /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from direct assay /// 0001222 // transcription corepressor binding // inferred from mutant phenotype /// 0002153 // steroid receptor RNA activator RNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // traceable author statement /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0004887 // thyroid hormone receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017025 // TBP-class protein binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from physical interaction 204101_at NM_000252 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000252.1 /DEF=Homo sapiens myotubular myopathy 1 (MTM1), mRNA. /FEA=mRNA /GEN=MTM1 /PROD=myotubularin /DB_XREF=gi:4557895 /UG=Hs.75302 myotubular myopathy 1 /FL=gb:U46024.1 gb:NM_000252.1" NM_000252 myotubularin 1 MTM1 4534 NM_000252 /// XM_005274687 /// XM_006724820 /// XM_006724821 /// XM_006724822 0006470 // protein dephosphorylation // inferred from direct assay /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0044088 // regulation of vacuole organization // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045109 // intermediate filament organization // inferred from mutant phenotype /// 0046716 // muscle cell cellular homeostasis // inferred from electronic annotation /// 0046856 // phosphatidylinositol dephosphorylation // inferred from direct assay /// 0048311 // mitochondrion distribution // inferred from mutant phenotype /// 0070584 // mitochondrion morphogenesis // inferred from direct assay 0001726 // ruffle // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0031674 // I band // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004438 // phosphatidylinositol-3-phosphatase activity // inferred from direct assay /// 0004721 // phosphoprotein phosphatase activity // inferred from direct assay /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0019215 // intermediate filament binding // inferred from direct assay /// 0035091 // phosphatidylinositol binding // inferred from direct assay /// 0052629 // phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity // inferred from direct assay" 204102_s_at NM_001961 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001961.1 /DEF=Homo sapiens eukaryotic translation elongation factor 2 (EEF2), mRNA. /FEA=mRNA /GEN=EEF2 /PROD=eukaryotic translation elongation factor 2 /DB_XREF=gi:4503482 /UG=Hs.75309 eukaryotic translation elongation factor 2 /FL=gb:NM_001961.1" NM_001961 eukaryotic translation elongation factor 2 EEF2 1938 NM_001961 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045727 // positive regulation of translation // inferred from genetic interaction 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005844 // polysome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008494 // translation activator activity // inferred from genetic interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204103_at NM_002984 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002984.1 /DEF=Homo sapiens small inducible cytokine A4 (homologous to mouse Mip-1b) (SCYA4), mRNA. /FEA=mRNA /GEN=SCYA4 /PROD=small inducible cytokine A4 (homologous to mouseMip-1b) /DB_XREF=gi:4506844 /UG=Hs.75703 small inducible cytokine A4 (homologous to mouse Mip-1b) /FL=gb:J04130.1 gb:NM_002984.1 gb:M23502.1 gb:M25316.1" NM_002984 chemokine (C-C motif) ligand 4 CCL4 6351 NM_002984 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0009636 // response to toxic substance // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0050850 // positive regulation of calcium-mediated signaling // inferred from mutant phenotype /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 2000503 // positive regulation of natural killer cell chemotaxis // inferred from direct assay 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005125 // cytokine activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation /// 0031726 // CCR1 chemokine receptor binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204104_at NM_003083 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003083.1 /DEF=Homo sapiens small nuclear RNA activating complex, polypeptide 2, 45kD (SNAPC2), mRNA. /FEA=mRNA /GEN=SNAPC2 /PROD=small nuclear RNA activating complex,polypeptide 2, 45kD /DB_XREF=gi:4507102 /UG=Hs.78403 small nuclear RNA activating complex, polypeptide 2, 45kD /FL=gb:U44755.1 gb:U44898.1 gb:NM_003083.1" NM_003083 "small nuclear RNA activating complex, polypeptide 2, 45kDa" SNAPC2 6618 NM_003083 /// NR_030717 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009301 // snRNA transcription // traceable author statement /// 0010467 // gene expression // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement 204105_s_at NM_005010 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005010.1 /DEF=Homo sapiens neuronal cell adhesion molecule (NRCAM), mRNA. /FEA=mRNA /GEN=NRCAM /PROD=neuronal cell adhesion molecule /DB_XREF=gi:4826863 /UG=Hs.7912 neuronal cell adhesion molecule /FL=gb:AB002341.1 gb:NM_005010.1" NM_005010 neuronal cell adhesion molecule NRCAM 4897 NM_001037132 /// NM_001037133 /// NM_001193582 /// NM_001193583 /// NM_001193584 /// NM_005010 /// XM_005250373 /// XM_005250380 /// XM_005250383 /// XM_005250385 /// XM_006716003 /// XM_006716004 /// XM_006716005 /// XM_006716006 /// XM_006716007 /// XM_006716008 /// XM_006716009 /// XM_006716010 /// XM_006716011 /// XM_006716012 /// XM_006716013 /// XM_006716014 /// XR_428177 /// XR_428178 0001525 // angiogenesis // inferred from expression pattern /// 0001764 // neuron migration // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007409 // axonogenesis // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // non-traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0030516 // regulation of axon extension // non-traceable author statement /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0045162 // clustering of voltage-gated sodium channels // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // non-traceable author statement /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from direct assay /// 0086080 // protein binding involved in heterotypic cell-cell adhesion // inferred from electronic annotation 204106_at NM_006285 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006285.1 /DEF=Homo sapiens testis-specific kinase 1 (TESK1), mRNA. /FEA=mRNA /GEN=TESK1 /PROD=testis-specific protein kinase 1 /DB_XREF=gi:5454109 /UG=Hs.79358 testis-specific kinase 1 /FL=gb:D50863.1 gb:NM_006285.1" NM_006285 testis-specific kinase 1 TESK1 7016 NM_006285 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204107_at BF445142 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF445142 /FEA=EST /DB_XREF=gi:11510203 /DB_XREF=est:nad21b05.x1 /CLONE=IMAGE:3366081 /UG=Hs.797 nuclear transcription factor Y, alpha /FL=gb:NM_002505.2 gb:M59079.1" BF445142 "nuclear transcription factor Y, alpha" NFYA 4800 NM_002505 /// NM_021705 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204108_at AL031778 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AL031778 /DEF=Human DNA sequence from clone 34B21 on chromosome 6p12.1-21.1. Contains part of a gene for a novel protein with ZU5 domain similar to part of Tight Junction Protein ZO1 (TJP1) and UNC5 Homologs, the gene for a novel BZRP (peripheral benzodiazapine... /FEA=mRNA_5 /DB_XREF=gi:4153958 /UG=Hs.797 nuclear transcription factor Y, alpha /FL=gb:NM_002505.2 gb:M59079.1" AL031778 "nuclear transcription factor Y, alpha" NFYA 4800 NM_002505 /// NM_021705 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204109_s_at NM_002505 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002505.2 /DEF=Homo sapiens nuclear transcription factor Y, alpha (NFYA), transcript variant 1, mRNA. /FEA=mRNA /GEN=NFYA /PROD=nuclear transcription factor Y, alpha, isoform1 /DB_XREF=gi:11496975 /UG=Hs.797 nuclear transcription factor Y, alpha /FL=gb:NM_002505.2 gb:M59079.1" NM_002505 "nuclear transcription factor Y, alpha" NFYA 4800 NM_002505 /// NM_021705 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0016602 // CCAAT-binding factor complex // inferred from direct assay 0001046 // core promoter sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204110_at U08092 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:U08092.1 /DEF=Human histamine N-methyltransferase (HNMT) mRNA, complete cds. /FEA=mRNA /GEN=HNMT /PROD=histamine N-methyltransferase /DB_XREF=gi:468258 /UG=Hs.81182 histamine N-methyltransferase /FL=gb:U08092.1 gb:D16224.1 gb:NM_006895.1" U08092 histamine N-methyltransferase HNMT 3176 NM_001024074 /// NM_001024075 /// NM_006895 /// XM_005263654 0002347 // response to tumor cell // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0014075 // response to amine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046539 // histamine N-methyltransferase activity // inferred from electronic annotation 204111_at N40285 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N40285 /FEA=EST /DB_XREF=gi:1163830 /DB_XREF=est:yx80c01.r1 /CLONE=IMAGE:268032 /UG=Hs.81182 histamine N-methyltransferase /FL=gb:U08092.1 gb:D16224.1 gb:NM_006895.1 N40285 histamine N-methyltransferase HNMT 3176 NM_001024074 /// NM_001024075 /// NM_006895 /// XM_005263654 0002347 // response to tumor cell // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0014075 // response to amine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046539 // histamine N-methyltransferase activity // inferred from electronic annotation 204112_s_at NM_006895 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006895.1 /DEF=Homo sapiens histamine N-methyltransferase (HNMT), mRNA. /FEA=mRNA /GEN=HNMT /PROD=histamine N-methyltransferase /DB_XREF=gi:5901969 /UG=Hs.81182 histamine N-methyltransferase /FL=gb:U08092.1 gb:D16224.1 gb:NM_006895.1" NM_006895 histamine N-methyltransferase HNMT 3176 NM_001024074 /// NM_001024075 /// NM_006895 /// XM_005263654 0002347 // response to tumor cell // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006972 // hyperosmotic response // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // traceable author statement /// 0014075 // response to amine // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008170 // N-methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046539 // histamine N-methyltransferase activity // inferred from electronic annotation 204113_at NM_006560 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006560.1 /DEF=Homo sapiens CUG triplet repeat, RNA-binding protein 1 (CUGBP1), mRNA. /FEA=mRNA /GEN=CUGBP1 /PROD=CUG triplet repeat, RNA-binding protein 1 /DB_XREF=gi:5729793 /UG=Hs.81248 CUG triplet repeat, RNA-binding protein 1 /FL=gb:U63289.1 gb:NM_006560.1 gb:AF267533.1 gb:AF267534.1" NM_006560 "CUGBP, Elav-like family member 1" CELF1 10658 NM_001025596 /// NM_001172639 /// NM_001172640 /// NM_006560 /// NM_198700 /// XM_005252754 /// XM_005252755 /// XM_005252756 /// XM_006718122 /// XM_006718123 /// XM_006718124 /// XM_006718125 /// XM_006718126 /// XM_006718127 /// XM_006718128 /// XM_006718129 /// XM_006718130 /// XM_006718131 0006376 // mRNA splice site selection // inferred from sequence or structural similarity /// 0006397 // mRNA processing // traceable author statement /// 0007281 // germ cell development // non-traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009790 // embryo development // non-traceable author statement /// 0016246 // RNA interference // non-traceable author statement /// 0017148 // negative regulation of translation // non-traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030529 // ribonucleoprotein complex // non-traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0000900 // translation repressor activity, nucleic acid binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0031369 // translation initiation factor binding // inferred from electronic annotation /// 0042835 // BRE binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay" 204114_at NM_007361 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007361.1 /DEF=Homo sapiens nidogen 2 (NID2), mRNA. /FEA=mRNA /GEN=NID2 /PROD=nidogen 2 /DB_XREF=gi:6679055 /UG=Hs.82733 nidogen 2 /FL=gb:D86425.1 gb:NM_007361.1" NM_007361 nidogen 2 (osteonidogen) NID2 22795 NM_007361 /// XM_005267405 /// XM_005267406 /// XM_005267407 /// XM_006720079 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0071711 // basement membrane organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement 204115_at NM_004126 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004126.1 /DEF=Homo sapiens guanine nucleotide binding protein 11 (GNG11), mRNA. /FEA=mRNA /GEN=GNG11 /PROD=guanine nucleotide binding protein 11 /DB_XREF=gi:4758447 /UG=Hs.83381 guanine nucleotide binding protein 11 /FL=gb:NM_004126.1 gb:U31384.1" NM_004126 "guanine nucleotide binding protein (G protein), gamma 11" GNG11 2791 NM_004126 0006112 // energy reserve metabolic process // traceable author statement /// 0006184 // GTP catabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0071377 // cellular response to glucagon stimulus // traceable author statement 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation 204116_at NM_000206 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000206.1 /DEF=Homo sapiens interleukin 2 receptor, gamma (severe combined immunodeficiency) (IL2RG), mRNA. /FEA=mRNA /GEN=IL2RG /PROD=interleukin 2 receptor, gamma chain, precursor /DB_XREF=gi:4557881 /UG=Hs.84 interleukin 2 receptor, gamma (severe combined immunodeficiency) /FL=gb:NM_000206.1" NM_000206 "interleukin 2 receptor, gamma" IL2RG 3561 NM_000206 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0035771 // interleukin-4-mediated signaling pathway // traceable author statement /// 0038110 // interleukin-2-mediated signaling pathway // traceable author statement /// 0038111 // interleukin-7-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004911 // interleukin-2 receptor activity // traceable author statement /// 0004913 // interleukin-4 receptor activity // traceable author statement /// 0004917 // interleukin-7 receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019976 // interleukin-2 binding // inferred from sequence or structural similarity /// 0019982 // interleukin-7 binding // inferred from electronic annotation 204117_at NM_002726 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002726.1 /DEF=Homo sapiens prolyl endopeptidase (PREP), mRNA. /FEA=mRNA /GEN=PREP /PROD=prolyl endopeptidase /DB_XREF=gi:4506042 /UG=Hs.86978 prolyl endopeptidase /FL=gb:AB028867.1 gb:NM_002726.1 gb:AB020018.1 gb:D21102.1" NM_002726 prolyl endopeptidase PREP 5550 NM_002726 /// XM_005267044 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0070008 // serine-type exopeptidase activity // inferred from electronic annotation 204118_at NM_001778 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001778.1 /DEF=Homo sapiens CD48 antigen (B-cell membrane protein) (CD48), mRNA. /FEA=mRNA /GEN=CD48 /PROD=CD48 antigen (B-cell membrane protein) /DB_XREF=gi:4502674 /UG=Hs.901 CD48 antigen (B-cell membrane protein) /FL=gb:M59904.1 gb:M37766.1 gb:NM_001778.1" NM_001778 CD48 molecule CD48 962 NM_001256030 /// NM_001778 /// XM_005245625 /// XM_006711640 0006952 // defense response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0042110 // T cell activation // inferred from electronic annotation /// 0045576 // mast cell activation // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0046658 // anchored component of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003823 // antigen binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204119_s_at U90339 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U90339.1 /DEF=Human adenosine kinase short form mRNA, complete cds. /FEA=mRNA /PROD=adenosine kinase short form /DB_XREF=gi:1906010 /UG=Hs.94382 adenosine kinase /FL=gb:U50196.1 gb:BC003568.1 gb:U90339.1 gb:NM_001123.1" U90339 adenosine kinase ADK 132 NM_001123 /// NM_001202449 /// NM_001202450 /// NM_006721 /// XM_005269538 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0006175 // dATP biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044209 // AMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0046085 // adenosine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004001 // adenosine kinase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 204120_s_at NM_001123 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001123.1 /DEF=Homo sapiens adenosine kinase (ADK), transcript variant ADK-short, mRNA. /FEA=mRNA /GEN=ADK /PROD=adenosine kinase, isoform a /DB_XREF=gi:4501942 /UG=Hs.94382 adenosine kinase /FL=gb:U50196.1 gb:BC003568.1 gb:U90339.1 gb:NM_001123.1" NM_001123 adenosine kinase ADK 132 NM_001123 /// NM_001202449 /// NM_001202450 /// NM_006721 /// XM_005269538 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006166 // purine ribonucleoside salvage // inferred from electronic annotation /// 0006167 // AMP biosynthetic process // inferred from electronic annotation /// 0006175 // dATP biosynthetic process // inferred from electronic annotation /// 0009156 // ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044209 // AMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044342 // type B pancreatic cell proliferation // inferred from electronic annotation /// 0046085 // adenosine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004001 // adenosine kinase activity // not recorded /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 204121_at NM_006705 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006705.2 /DEF=Homo sapiens growth arrest and DNA-damage-inducible, gamma (GADD45G), mRNA. /FEA=mRNA /GEN=GADD45G /PROD=growth arrest and DNA-damage-inducible, gamma /DB_XREF=gi:9790905 /UG=Hs.9701 growth arrest and DNA-damage-inducible, gamma /FL=gb:AF087883.1 gb:BC000465.1 gb:AF078078.1 gb:AF079806.1 gb:D83023.1 gb:NM_006705.2" NM_006705 "growth arrest and DNA-damage-inducible, gamma" GADD45G 10912 NM_006705 0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204122_at NM_003332 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003332.1 /DEF=Homo sapiens TYRO protein tyrosine kinase binding protein (TYROBP), mRNA. /FEA=mRNA /GEN=TYROBP /PROD=TYRO protein tyrosine kinase binding protein /DB_XREF=gi:4507754 /UG=Hs.9963 TYRO protein tyrosine kinase binding protein /FL=gb:AF019562.1 gb:NM_003332.1" NM_003332 TYRO protein tyrosine kinase binding protein TYROBP 7305 NM_001173514 /// NM_001173515 /// NM_003332 /// NM_198125 /// NR_033390 /// XM_006723350 0002281 // macrophage activation involved in immune response // inferred from electronic annotation /// 0002283 // neutrophil activation involved in immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050776 // regulation of immune response // traceable author statement /// 2001204 // regulation of osteoclast development // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 204123_at NM_013975 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013975.1 /DEF=Homo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant alpha, mRNA. /FEA=mRNA /GEN=LIG3 /PROD=ligase III, DNA, ATP-dependent, isoform alpha /DB_XREF=gi:7710125 /UG=Hs.100299 ligase III, DNA, ATP-dependent /FL=gb:NM_013975.1" NM_013975 "ligase III, DNA, ATP-dependent" LIG3 3980 NM_002311 /// NM_013975 /// XM_005257970 /// XM_005257971 /// XM_006721896 "0006260 // DNA replication // inferred from electronic annotation /// 0006273 // lagging strand elongation // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006288 // base-excision repair, DNA ligation // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // not recorded /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0033151 // V(D)J recombination // inferred from direct assay /// 0043504 // mitochondrial DNA repair // inferred from electronic annotation /// 0045910 // negative regulation of DNA recombination // inferred from electronic annotation /// 0051103 // DNA ligation involved in DNA repair // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation" 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000795 // synaptonemal complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // not recorded /// 0005739 // mitochondrion // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003909 // DNA ligase activity // inferred from direct assay /// 0003910 // DNA ligase (ATP) activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204124_at AF146796 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF146796.1 /DEF=Homo sapiens sodium dependent phosphate transporter isoform NaPi-IIb mRNA, complete cds. /FEA=mRNA /PROD=sodium dependent phosphate transporter isoformNaPi-IIb /DB_XREF=gi:6910977 /UG=Hs.105039 solute carrier family 34 (sodium phosphate), member 2 /FL=gb:AF111856.1 gb:NM_006424.1 gb:AF146796.1" AF146796 "solute carrier family 34 (type II sodium/phosphate contransporter), member 2" SLC34A2 10568 NM_001177998 /// NM_001177999 /// NM_006424 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009750 // response to fructose // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030643 // cellular phosphate ion homeostasis // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0031528 // microvillus membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from direct assay /// 0042301 // phosphate ion binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation" 204125_at NM_016013 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016013.1 /DEF=Homo sapiens CGI-65 protein (LOC51103), mRNA. /FEA=mRNA /GEN=LOC51103 /PROD=CGI-65 protein /DB_XREF=gi:7705778 /UG=Hs.106529 CGI-65 protein /FL=gb:BC000780.1 gb:AF151823.1 gb:NM_016013.1" NM_016013 "NADH dehydrogenase (ubiquinone) complex I, assembly factor 1" NDUFAF1 51103 NM_016013 /// NR_045620 /// XM_006720555 /// XM_006720556 /// XM_006720557 /// XM_006720558 "0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006461 // protein complex assembly // non-traceable author statement" 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // non-traceable author statement 204126_s_at NM_003504 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003504.1 /DEF=Homo sapiens CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like (CDC45L), mRNA. /FEA=mRNA /GEN=CDC45L /PROD=CDC45 (cell division cycle 45, S.cerevisiae,homolog)-like /DB_XREF=gi:4502712 /UG=Hs.114311 CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like /FL=gb:AF053074.1 gb:AF062495.1 gb:AF081535.1 gb:NM_003504.1" NM_003504 cell division cycle 45 CDC45 8318 NM_001178010 /// NM_001178011 /// NM_003504 /// XM_005261285 /// XM_005261286 0000076 // DNA replication checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204127_at BC000149 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000149.2 /DEF=Homo sapiens, replication factor C (activator 1) 3 (38kD), clone MGC:5276, mRNA, complete cds. /FEA=mRNA /PROD=replication factor C (activator 1) 3 (38kD) /DB_XREF=gi:12803002 /UG=Hs.115474 replication factor C (activator 1) 3 (38kD) /FL=gb:BC000149.2 gb:L07541.1 gb:NM_002915.1" BC000149 "replication factor C (activator 1) 3, 38kDa" RFC3 5983 NM_002915 /// NM_181558 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0046683 // response to organophosphorus // inferred from expression pattern" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005663 // DNA replication factor C complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003689 // DNA clamp loader activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 204128_s_at NM_002915 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002915.1 /DEF=Homo sapiens replication factor C (activator 1) 3 (38kD) (RFC3), mRNA. /FEA=mRNA /GEN=RFC3 /PROD=replication factor C (activator 1) 3 (38kD) /DB_XREF=gi:4506488 /UG=Hs.115474 replication factor C (activator 1) 3 (38kD) /FL=gb:BC000149.2 gb:L07541.1 gb:NM_002915.1" NM_002915 "replication factor C (activator 1) 3, 38kDa" RFC3 5983 NM_002915 /// NM_181558 "0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0046683 // response to organophosphorus // inferred from expression pattern" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005663 // DNA replication factor C complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003689 // DNA clamp loader activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 204129_at NM_004326 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004326.1 /DEF=Homo sapiens B-cell CLLlymphoma 9 (BCL9), mRNA. /FEA=mRNA /GEN=BCL9 /PROD=B-cell CLLlymphoma 9 /DB_XREF=gi:4757845 /UG=Hs.122607 B-cell CLLlymphoma 9 /FL=gb:NM_004326.1" NM_004326 B-cell CLL/lymphoma 9 BCL9 607 NM_004326 /// XM_005272971 /// XM_005277417 /// XM_005277418 /// XM_006711483 0014908 // myotube differentiation involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation 204130_at NM_000196 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000196.1 /DEF=Homo sapiens hydroxysteroid (11-beta) dehydrogenase 2 (HSD11B2), mRNA. /FEA=mRNA /GEN=HSD11B2 /PROD=hydroxysteroid (11-beta) dehydrogenase 2 /DB_XREF=gi:4504498 /UG=Hs.1376 hydroxysteroid (11-beta) dehydrogenase 2 /FL=gb:U26726.1 gb:U14631.1 gb:NM_000196.1" NM_000196 hydroxysteroid (11-beta) dehydrogenase 2 HSD11B2 3291 NM_000196 0001666 // response to hypoxia // inferred from electronic annotation /// 0002017 // regulation of blood volume by renal aldosterone // inferred from electronic annotation /// 0006704 // glucocorticoid biosynthetic process // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008211 // glucocorticoid metabolic process // inferred from electronic annotation /// 0032094 // response to food // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0003845 // 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 204131_s_at N25732 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N25732 /FEA=EST /DB_XREF=gi:1140080 /DB_XREF=est:yx83c03.s1 /CLONE=IMAGE:268324 /UG=Hs.14845 forkhead box O3A /FL=gb:AF032886.1 gb:NM_001455.1 N25732 forkhead box O3 FOXO3 2309 NM_001455 /// NM_201559 /// XM_005266867 /// XM_005266868 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001544 // initiation of primordial ovarian follicle growth // inferred from electronic annotation /// 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // not recorded /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // not recorded /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // not recorded /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation "0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay" 204132_s_at NM_001455 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001455.1 /DEF=Homo sapiens forkhead box O3A (FOXO3A), mRNA. /FEA=mRNA /GEN=FOXO3A /PROD=forkhead box O3A /DB_XREF=gi:4503738 /UG=Hs.14845 forkhead box O3A /FL=gb:AF032886.1 gb:NM_001455.1" NM_001455 forkhead box O3 /// forkhead box O3B pseudogene FOXO3 /// FOXO3B 2309 /// 2310 NM_001455 /// NM_201559 /// NR_026718 /// XM_005266867 /// XM_005266868 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001542 // ovulation from ovarian follicle // inferred from electronic annotation /// 0001544 // initiation of primordial ovarian follicle growth // inferred from electronic annotation /// 0001547 // antral ovarian follicle growth // inferred from electronic annotation /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006417 // regulation of translation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // not recorded /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007389 // pattern specification process // not recorded /// 0008286 // insulin receptor signaling pathway // not recorded /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009790 // embryo development // /// 0009888 // tissue development // not recorded /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042127 // regulation of cell proliferation // not recorded /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation "0001047 // core promoter binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008301 // DNA binding, bending // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay" 204133_at NM_004704 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004704.1 /DEF=Homo sapiens U3 snoRNP-associated 55-kDa protein (U3-55K), mRNA. /FEA=mRNA /GEN=U3-55K /PROD=U3 snoRNP-associated 55-kDa protein /DB_XREF=gi:4759275 /UG=Hs.153768 U3 snoRNP-associated 55-kDa protein /FL=gb:BC001113.1 gb:NM_004704.1" NM_004704 "ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)" RRP9 9136 NM_004704 0006364 // rRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005732 // small nucleolar ribonucleoprotein complex // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204134_at NM_002599 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002599.1 /DEF=Homo sapiens phosphodiesterase 2A, cGMP-stimulated (PDE2A), mRNA. /FEA=mRNA /GEN=PDE2A /PROD=phosphodiesterase 2A, cGMP-stimulated /DB_XREF=gi:4505656 /UG=Hs.154437 phosphodiesterase 2A, cGMP-stimulated /FL=gb:U67733.1 gb:NM_002599.1" NM_002599 "phosphodiesterase 2A, cGMP-stimulated" PDE2A 5138 NM_001143839 /// NM_001146209 /// NM_001243784 /// NM_002599 /// XM_005274040 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from direct assay /// 0006198 // cAMP catabolic process // inferred from mutant phenotype /// 0006626 // protein targeting to mitochondrion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from direct assay /// 0019933 // cAMP-mediated signaling // inferred from mutant phenotype /// 0019934 // cGMP-mediated signaling // inferred from mutant phenotype /// 0030224 // monocyte differentiation // inferred from expression pattern /// 0030818 // negative regulation of cAMP biosynthetic process // inferred from sequence or structural similarity /// 0033159 // negative regulation of protein import into nucleus, translocation // inferred from direct assay /// 0035690 // cellular response to drug // inferred from expression pattern /// 0035690 // cellular response to drug // inferred from mutant phenotype /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from direct assay /// 0043116 // negative regulation of vascular permeability // inferred from mutant phenotype /// 0043117 // positive regulation of vascular permeability // inferred from mutant phenotype /// 0046069 // cGMP catabolic process // inferred from direct assay /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0061028 // establishment of endothelial barrier // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0071260 // cellular response to mechanical stimulus // inferred from sequence or structural similarity /// 0071321 // cellular response to cGMP // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from expression pattern /// 0097011 // cellular response to granulocyte macrophage colony-stimulating factor stimulus // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004118 // cGMP-stimulated cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0005262 // calcium channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from mutant phenotype /// 0030553 // cGMP binding // inferred from direct assay /// 0030553 // cGMP binding // inferred from mutant phenotype /// 0030911 // TPR domain binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation" 204135_at NM_014890 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014890.1 /DEF=Homo sapiens downregulated in ovarian cancer 1 (DOC1), mRNA. /FEA=mRNA /GEN=DOC1 /PROD=downregulated in ovarian cancer 1 /DB_XREF=gi:7657036 /UG=Hs.15432 downregulated in ovarian cancer 1 /FL=gb:U53445.1 gb:NM_014890.1" NM_014890 filamin A interacting protein 1-like FILIP1L 11259 NM_001042459 /// NM_001282793 /// NM_001282794 /// NM_014890 /// NM_182909 /// XM_006713486 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016459 // myosin complex // non-traceable author statement 204136_at NM_000094 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000094.1 /DEF=Homo sapiens collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) (COL7A1), mRNA. /FEA=mRNA /GEN=COL7A1 /PROD=collagen, type VII, alpha 1 (epidermolysisbullosa, dystrophic, dominant and recessive) /DB_XREF=gi:4502960 /UG=Hs.1640 collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) /FL=gb:NM_000094.1 gb:L02870.1" NM_000094 "collagen, type VII, alpha 1" COL7A1 1294 NM_000094 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005590 // collagen type VII trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from sequence or structural similarity 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204137_at NM_003272 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003272.1 /DEF=Homo sapiens transmembrane 7 superfamily member 1 (upregulated in kidney) (TM7SF1), mRNA. /FEA=mRNA /GEN=TM7SF1 /PROD=transmembrane 7 superfamily member 1(upregulated in kidney) /DB_XREF=gi:4507544 /UG=Hs.15791 transmembrane 7 superfamily member 1 (upregulated in kidney) /FL=gb:AF027826.1 gb:NM_003272.1" NM_003272 G protein-coupled receptor 137B GPR137B 7107 NM_003272 /// XM_005273244 /// XR_247039 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 204138_s_at AI762174 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI762174 /FEA=EST /DB_XREF=gi:5177841 /DB_XREF=est:wh90g05.x1 /CLONE=IMAGE:2388056 /UG=Hs.169832 zinc finger protein 42 (myeloid-specific retinoic acid- responsive) /FL=gb:M58297.1 gb:NM_003422.1 AI762174 myeloid zinc finger 1 MZF1 7593 NM_001267033 /// NM_003422 /// NM_198055 /// XM_005259203 /// XM_005259204 /// XM_006723358 /// XM_006723359 /// XM_006723360 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204139_x_at NM_003422 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003422.1 /DEF=Homo sapiens zinc finger protein 42 (myeloid-specific retinoic acid- responsive) (ZNF42), mRNA. /FEA=mRNA /GEN=ZNF42 /PROD=zinc finger protein 42 (myeloid-specificretinoic acid- responsive) /DB_XREF=gi:4508024 /UG=Hs.169832 zinc finger protein 42 (myeloid-specific retinoic acid- responsive) /FL=gb:M58297.1 gb:NM_003422.1" NM_003422 myeloid zinc finger 1 MZF1 7593 NM_001267033 /// NM_003422 /// NM_198055 /// XM_005259203 /// XM_005259204 /// XM_006723358 /// XM_006723359 /// XM_006723360 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from electronic annotation 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204140_at NM_003596 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003596.1 /DEF=Homo sapiens tyrosylprotein sulfotransferase 1 (TPST1), mRNA. /FEA=mRNA /GEN=TPST1 /PROD=tyrosylprotein sulfotransferase 1 /DB_XREF=gi:4507664 /UG=Hs.17279 tyrosylprotein sulfotransferase 1 /FL=gb:AF038009.1 gb:NM_003596.1" NM_003596 tyrosylprotein sulfotransferase 1 TPST1 8460 NM_003596 /// XM_005250642 0006478 // peptidyl-tyrosine sulfation // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0008146 // sulfotransferase activity // inferred from electronic annotation /// 0008476 // protein-tyrosine sulfotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204141_at NM_001069 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001069.1 /DEF=Homo sapiens tubulin, beta polypeptide (TUBB), mRNA. /FEA=mRNA /GEN=TUBB /PROD=tubulin, beta polypeptide /DB_XREF=gi:4507728 /UG=Hs.179661 tubulin, beta polypeptide /FL=gb:BC001194.1 gb:NM_001069.1" NM_001069 "tubulin, beta 2A class IIa" TUBB2A 7280 NM_001069 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051084 // 'de novo' posttranslational protein folding // traceable author statement /// 0051258 // protein polymerization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 204142_at NM_017512 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017512.1 /DEF=Homo sapiens rTS beta protein (HSRTSBETA), mRNA. /FEA=mRNA /GEN=HSRTSBETA /PROD=rTS beta protein /DB_XREF=gi:8923790 /UG=Hs.180433 rTS beta protein /FL=gb:BC001285.1 gb:NM_017512.1" NM_017512 enolase superfamily member 1 ENOSF1 55556 NM_001126123 /// NM_017512 /// NM_202758 /// XM_005258118 /// XR_243810 /// XR_243811 /// XR_430041 /// XR_430042 /// XR_430043 /// XR_430044 /// XR_430045 0008152 // metabolic process // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // inferred from electronic annotation /// 0044275 // cellular carbohydrate catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050023 // L-fuconate dehydratase activity // inferred from direct assay 204143_s_at NM_017512 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017512.1 /DEF=Homo sapiens rTS beta protein (HSRTSBETA), mRNA. /FEA=mRNA /GEN=HSRTSBETA /PROD=rTS beta protein /DB_XREF=gi:8923790 /UG=Hs.180433 rTS beta protein /FL=gb:BC001285.1 gb:NM_017512.1" NM_017512 enolase superfamily member 1 ENOSF1 55556 NM_001126123 /// NM_017512 /// NM_202758 /// XM_005258118 /// XR_243810 /// XR_243811 /// XR_430041 /// XR_430042 /// XR_430043 /// XR_430044 /// XR_430045 0008152 // metabolic process // inferred from electronic annotation /// 0009063 // cellular amino acid catabolic process // inferred from electronic annotation /// 0044275 // cellular carbohydrate catabolic process // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050023 // L-fuconate dehydratase activity // inferred from direct assay 204144_s_at NM_004204 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004204.1 /DEF=Homo sapiens phosphatidylinositol glycan, class Q (PIGQ), mRNA. /FEA=mRNA /GEN=PIGQ /PROD=phosphatidylinositol glycan, class Q /DB_XREF=gi:4758465 /UG=Hs.18079 phosphatidylinositol glycan, class Q /FL=gb:AF030177.1 gb:AB003723.1 gb:NM_004204.1" NM_004204 "phosphatidylinositol glycan anchor biosynthesis, class Q" PIGQ 9091 NM_004204 /// NM_148920 0005975 // carbohydrate metabolic process // traceable author statement /// 0006501 // C-terminal protein lipidation // traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement 0000506 // glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0017176 // phosphatidylinositol N-acetylglucosaminyltransferase activity // inferred from electronic annotation" 204145_at NM_004477 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004477.1 /DEF=Homo sapiens FSHD region gene 1 (FRG1), mRNA. /FEA=mRNA /GEN=FRG1 /PROD=FSHD region gene 1 /DB_XREF=gi:4758403 /UG=Hs.203772 FSHD region gene 1 /FL=gb:L76159.1 gb:NM_004477.1" NM_004477 FSHD region gene 1 /// protein FRG1-like /// uncharacterized LOC101930278 /// protein FRG1-like FRG1 /// LOC100289097 /// LOC101930278 /// LOC101930531 2483 /// 100289097 /// 101930278 /// 101930531 NM_004477 /// XM_005262879 /// XM_005262880 /// XM_006714166 /// XM_006725445 /// XM_006725446 /// XM_006725447 /// XR_250590 /// XR_250603 /// XR_426484 /// XR_430284 /// XR_430390 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0015030 // Cajal body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay "0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation" 204146_at BE966146 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE966146 /FEA=EST /DB_XREF=gi:11771248 /DB_XREF=est:601660074R1 /CLONE=IMAGE:3905635 /UG=Hs.24596 RAD51-interacting protein /FL=gb:AF006259.1 gb:NM_006479.1 BE966146 RAD51 associated protein 1 RAD51AP1 10635 NM_001130862 /// NM_006479 /// XM_006718952 /// XM_006718953 /// XM_006718954 /// XM_006718955 0000724 // double-strand break repair via homologous recombination // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay 0005634 // nucleus // inferred by curator 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204147_s_at NM_007111 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007111.1 /DEF=Homo sapiens transcription factor Dp-1 (TFDP1), mRNA. /FEA=mRNA /GEN=TFDP1 /PROD=transcription factor Dp-1 /DB_XREF=gi:6005899 /UG=Hs.279576 transcription factor Dp-1 /FL=gb:L23959.1 gb:NM_007111.1" NM_007111 transcription factor Dp-1 TFDP1 7027 NM_007111 /// NR_026580 /// XM_005268326 /// XM_005268327 /// XM_005268328 /// XM_005268330 /// XM_005268331 /// XM_006719977 /// XM_006719978 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 204148_s_at NM_012230 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012230.1 /DEF=Homo sapiens POM (POM121 rat homolog) and ZP3 fusion protein (POMZP3), mRNA. /FEA=mRNA /GEN=POMZP3 /PROD=POM (POM121 rat homolog) and ZP3 fusion protein /DB_XREF=gi:6912599 /UG=Hs.296380 POM (POM121 rat homolog) and ZP3 fusion protein /FL=gb:U10099.1 gb:NM_012230.1" NM_012230 POM121 and ZP3 fusion /// zona pellucida glycoprotein 3 (sperm receptor) POMZP3 /// ZP3 7784 /// 22932 NM_001110354 /// NM_007155 /// NM_012230 /// NM_152992 "0001809 // positive regulation of type IV hypersensitivity // inferred from sequence or structural similarity /// 0001825 // blastocyst formation // inferred from sequence or structural similarity /// 0002455 // humoral immune response mediated by circulating immunoglobulin // inferred from sequence or structural similarity /// 0002687 // positive regulation of leukocyte migration // inferred from sequence or structural similarity /// 0002922 // positive regulation of humoral immune response // inferred from direct assay /// 0006828 // manganese ion transport // inferred from sequence or structural similarity /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from direct assay /// 0007339 // binding of sperm to zona pellucida // inferred from genetic interaction /// 0007339 // binding of sperm to zona pellucida // inferred from mutant phenotype /// 0007339 // binding of sperm to zona pellucida // traceable author statement /// 0010513 // positive regulation of phosphatidylinositol biosynthetic process // inferred from sequence or structural similarity /// 0032504 // multicellular organism reproduction // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035803 // egg coat formation // inferred from sequence or structural similarity /// 0042102 // positive regulation of T cell proliferation // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048015 // phosphatidylinositol-mediated signaling // inferred from sequence or structural similarity /// 0048599 // oocyte development // inferred from sequence or structural similarity /// 0050729 // positive regulation of inflammatory response // inferred from sequence or structural similarity /// 0051897 // positive regulation of protein kinase B signaling // inferred from sequence or structural similarity /// 0070528 // protein kinase C signaling // inferred from mutant phenotype /// 0070588 // calcium ion transmembrane transport // inferred from direct assay /// 0071421 // manganese ion transmembrane transport // inferred from sequence or structural similarity /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 2000344 // positive regulation of acrosome reaction // inferred from direct assay /// 2000360 // negative regulation of binding of sperm to zona pellucida // inferred from direct assay /// 2000368 // positive regulation of acrosomal vesicle exocytosis // inferred from direct assay /// 2000368 // positive regulation of acrosomal vesicle exocytosis // inferred from mutant phenotype /// 2000386 // positive regulation of ovarian follicle development // inferred from sequence or structural similarity /// 2000388 // positive regulation of antral ovarian follicle growth // inferred from sequence or structural similarity" 0001669 // acrosomal vesicle // inferred from sequence or structural similarity /// 0002081 // outer acrosomal membrane // inferred from sequence or structural similarity /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay /// 0005771 // multivesicular body // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0031012 // extracellular matrix // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005384 // manganese ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0015279 // store-operated calcium channel activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from direct assay /// 0032190 // acrosin binding // inferred from physical interaction 204149_s_at NM_000850 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000850.1 /DEF=Homo sapiens glutathione S-transferase M4 (GSTM4), mRNA. /FEA=mRNA /GEN=GSTM4 /PROD=glutathione S-transferase M4 /DB_XREF=gi:4504178 /UG=Hs.301961 glutathione S-transferase M4 /FL=gb:M96234.1 gb:NM_000850.1" NM_000850 glutathione S-transferase mu 4 GSTM4 2948 NM_000850 /// NM_147148 /// NM_147149 /// NR_024538 0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay 204150_at NM_015136 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015136.1 /DEF=Homo sapiens KIAA0246 protein (KIAA0246), mRNA. /FEA=mRNA /GEN=KIAA0246 /PROD=KIAA0246 protein /DB_XREF=gi:12225239 /UG=Hs.301989 KIAA0246 protein /FL=gb:NM_015136.1" NM_015136 stabilin 1 STAB1 23166 NM_015136 /// XM_005264973 /// XM_005264974 /// XM_005264975 /// XM_006713065 /// XM_006713066 /// XR_427261 0006898 // receptor-mediated endocytosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007267 // cell-cell signaling // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0042742 // defense response to bacterium // inferred from direct assay /// 0055114 // oxidation-reduction process // non-traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement 0005041 // low-density lipoprotein receptor activity // inferred from direct assay /// 0005044 // scavenger receptor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // non-traceable author statement /// 0030169 // low-density lipoprotein particle binding // inferred from direct assay 204151_x_at NM_001353 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001353.2 /DEF=Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1), mRNA. /FEA=mRNA /GEN=AKR1C1 /PROD=aldo-keto reductase family 1, member C1(dihydrodiol dehydrogenase 1; 20-alpha(3-alpha)-hydroxysteroid dehydrogenase) /DB_XREF=gi:5453542 /UG=Hs.306098 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) /FL=gb:U05684.1 gb:NM_001353.2 gb:M86609.1" NM_001353 "aldo-keto reductase family 1, member C1" AKR1C1 1645 NM_001353 "0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay" 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation" 204152_s_at AI738965 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI738965 /FEA=EST /DB_XREF=gi:5100946 /DB_XREF=est:wi12e11.x1 /CLONE=IMAGE:2390060 /UG=Hs.31939 manic fringe (Drosophila) homolog /FL=gb:U94352.1 gb:NM_002405.1 AI738965 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase MFNG 4242 NM_001166343 /// NM_002405 /// NR_029413 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation "0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033829 // O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204153_s_at NM_002405 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002405.1 /DEF=Homo sapiens manic fringe (Drosophila) homolog (MFNG), mRNA. /FEA=mRNA /GEN=MFNG /PROD=manic fringe (Drosophila) homolog /DB_XREF=gi:4505158 /UG=Hs.31939 manic fringe (Drosophila) homolog /FL=gb:U94352.1 gb:NM_002405.1" NM_002405 MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase MFNG 4242 NM_001166343 /// NM_002405 /// NR_029413 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation "0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033829 // O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204154_at NM_001801 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001801.1 /DEF=Homo sapiens cysteine dioxygenase, type I (CDO1), mRNA. /FEA=mRNA /GEN=CDO1 /PROD=cysteine dioxygenase, type I /DB_XREF=gi:4502754 /UG=Hs.3229 cysteine dioxygenase, type I /FL=gb:D85777.1 gb:NM_001801.1" NM_001801 cysteine dioxygenase type 1 CDO1 1036 NM_001801 /// XR_427700 0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000097 // sulfur amino acid biosynthetic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006534 // cysteine metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0019448 // L-cysteine catabolic process // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042412 // taurine biosynthetic process // inferred from electronic annotation /// 0042412 // taurine biosynthetic process // traceable author statement /// 0043200 // response to amino acid // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0046439 // L-cysteine metabolic process // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055114 // oxidation-reduction process // traceable author statement 0005829 // cytosol // traceable author statement 0005506 // iron ion binding // inferred from electronic annotation /// 0008198 // ferrous iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017172 // cysteine dioxygenase activity // inferred from sequence or structural similarity /// 0017172 // cysteine dioxygenase activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047800 // cysteamine dioxygenase activity // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation 204155_s_at AA044154 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA044154 /FEA=EST /DB_XREF=gi:1522030 /DB_XREF=est:zk50b06.r1 /CLONE=IMAGE:486227 /UG=Hs.4278 KIAA0999 protein /FL=gb:NM_025164.1 AA044154 SIK family kinase 3 SIK3 23387 NM_001281748 /// NM_001281749 /// NM_025164 /// XM_005271481 /// XM_005271482 /// XM_005271484 /// XM_005271485 /// XM_005271486 0001958 // endochondral ossification // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204156_at AA044154 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA044154 /FEA=EST /DB_XREF=gi:1522030 /DB_XREF=est:zk50b06.r1 /CLONE=IMAGE:486227 /UG=Hs.4278 KIAA0999 protein /FL=gb:NM_025164.1 AA044154 SIK family kinase 3 SIK3 23387 NM_001281748 /// NM_001281749 /// NM_025164 /// XM_005271481 /// XM_005271482 /// XM_005271484 /// XM_005271485 /// XM_005271486 0001958 // endochondral ossification // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204157_s_at NM_025164 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_025164.1 /DEF=Homo sapiens KIAA0999 protein (KIAA0999), mRNA. /FEA=mRNA /GEN=KIAA0999 /PROD=hypothetical protein FLJ12240 /DB_XREF=gi:13386467 /UG=Hs.4278 KIAA0999 protein /FL=gb:NM_025164.1" NM_025164 SIK family kinase 3 SIK3 23387 NM_001281748 /// NM_001281749 /// NM_025164 /// XM_005271481 /// XM_005271482 /// XM_005271484 /// XM_005271485 /// XM_005271486 0001958 // endochondral ossification // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0035108 // limb morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204158_s_at NM_006019 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006019.1 /DEF=Homo sapiens T-cell, immune regulator 1 (TCIRG1), mRNA. /FEA=mRNA /GEN=TCIRG1 /PROD=ATPase, H+ transporting, 116kD /DB_XREF=gi:5174620 /UG=Hs.46465 T-cell, immune regulator 1 /FL=gb:U45285.1 gb:NM_006019.1" NM_006019 "T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3" TCIRG1 10312 NM_006019 /// NM_006053 /// XM_005273709 /// XM_005273710 /// XM_006718417 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006968 // cellular defense response // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0033572 // transferrin transport // traceable author statement /// 0051701 // interaction with host // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 0090382 // phagosome maturation // traceable author statement "0000220 // vacuolar proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0010008 // endosome membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // traceable author statement /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation" 0005215 // transporter activity // traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 204159_at NM_001262 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001262.1 /DEF=Homo sapiens cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), mRNA. /FEA=mRNA /GEN=CDKN2C /PROD=cyclin-dependent kinase inhibitor 2C (p18,inhibits CDK4) /DB_XREF=gi:4502750 /UG=Hs.4854 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) /FL=gb:AF041248.1 gb:NM_001262.1" NM_001262 "cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)" CDKN2C 1031 NM_001262 /// NM_078626 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 204160_s_at AW194947 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW194947 /FEA=EST /DB_XREF=gi:6473915 /DB_XREF=est:xn32e06.x1 /CLONE=IMAGE:2695426 /UG=Hs.54037 ectonucleotide pyrophosphatasephosphodiesterase 4 (putative function) /FL=gb:AB020686.1 gb:NM_014936.1 AW194947 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) ENPP4 22875 NM_014936 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0046130 // purine ribonucleoside catabolic process // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047710 // bis(5'-adenosyl)-triphosphatase activity // inferred from direct assay 204161_s_at NM_014936 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014936.1 /DEF=Homo sapiens ectonucleotide pyrophosphatasephosphodiesterase 4 (putative function) (ENPP4), mRNA. /FEA=mRNA /GEN=ENPP4 /PROD=ectonucleotide pyrophosphatasephosphodiesterase4 (putative function) /DB_XREF=gi:7662357 /UG=Hs.54037 ectonucleotide pyrophosphatasephosphodiesterase 4 (putative function) /FL=gb:AB020686.1 gb:NM_014936.1" NM_014936 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) ENPP4 22875 NM_014936 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0046130 // purine ribonucleoside catabolic process // inferred from direct assay 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047710 // bis(5'-adenosyl)-triphosphatase activity // inferred from direct assay 204162_at NM_006101 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006101.1 /DEF=Homo sapiens highly expressed in cancer, rich in leucine heptad repeats (HEC), mRNA. /FEA=mRNA /GEN=HEC /PROD=highly expressed in cancer, rich in leucineheptad repeats /DB_XREF=gi:5174456 /UG=Hs.58169 highly expressed in cancer, rich in leucine heptad repeats /FL=gb:AF017790.1 gb:NM_006101.1" NM_006101 NDC80 kinetochore complex component NDC80 10403 NM_006101 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007052 // mitotic spindle organization // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // traceable author statement /// 0008608 // attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation "0000775 // chromosome, centromeric region // traceable author statement /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000942 // condensed nuclear chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031262 // Ndc80 complex // inferred from direct assay" 0005515 // protein binding // inferred from physical interaction 204163_at NM_007046 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007046.1 /DEF=Homo sapiens elastin microfibril interface located protein (EMILIN), mRNA. /FEA=mRNA /GEN=EMILIN /PROD=elastin microfibril interface located protein /DB_XREF=gi:5901943 /UG=Hs.63348 elastin microfibril interface located protein /FL=gb:AF088916.1 gb:NM_007046.1" NM_007046 elastin microfibril interfacer 1 EMILIN1 11117 NM_007046 /// XM_006711928 0007155 // cell adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation 204164_at NM_006747 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006747.1 /DEF=Homo sapiens signal-induced proliferation-associated gene 1 (SIPA1), mRNA. /FEA=mRNA /GEN=SIPA1 /PROD=signal-induced proliferation-associated gene 1 /DB_XREF=gi:5803168 /UG=Hs.7019 signal-induced proliferation-associated gene 1 /FL=gb:AB005666.1 gb:AF029789.1 gb:NM_006747.1" NM_006747 signal-induced proliferation-associated 1 SIPA1 6494 NM_006747 /// NM_153253 /// XM_005274189 /// XR_247210 0007010 // cytoskeleton organization // non-traceable author statement /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0032854 // positive regulation of Rap GTPase activity // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0045786 // negative regulation of cell cycle // non-traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0046582 // Rap GTPase activator activity // non-traceable author statement 204165_at NM_003931 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003931.1 /DEF=Homo sapiens WAS protein family, member 1 (WASF1), mRNA. /FEA=mRNA /GEN=WASF1 /PROD=WAS protein family, member 1 /DB_XREF=gi:4507912 /UG=Hs.75850 WAS protein family, member 1 /FL=gb:D87459.1 gb:NM_003931.1 gb:AF134303.1" NM_003931 "WAS protein family, member 1" WASF1 8936 NM_001024934 /// NM_001024935 /// NM_001024936 /// NM_003931 /// XM_005267203 /// XM_005267204 /// XM_005267205 /// XM_005267206 /// XM_005267207 /// XM_005267208 /// XM_006715595 0006461 // protein complex assembly // non-traceable author statement /// 0006928 // cellular component movement // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // traceable author statement /// 0072673 // lamellipodium morphogenesis // inferred from electronic annotation /// 2000601 // positive regulation of Arp2/3 complex-mediated actin nucleation // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031209 // SCAR complex // inferred from mutant phenotype /// 0045202 // synapse // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from mutant phenotype /// 0048365 // Rac GTPase binding // inferred from mutant phenotype 204166_at NM_014963 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014963.1 /DEF=Homo sapiens KIAA0963 protein (KIAA0963), mRNA. /FEA=mRNA /GEN=KIAA0963 /PROD=KIAA0963 protein /DB_XREF=gi:7662409 /UG=Hs.7724 KIAA0963 protein /FL=gb:AB023180.1 gb:NM_014963.1" NM_014963 strawberry notch homolog 2 (Drosophila) SBNO2 22904 NM_001100122 /// NM_014963 /// XM_005259519 /// XM_005259520 "0002281 // macrophage activation involved in immune response // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0050727 // regulation of inflammatory response // inferred from mutant phenotype" 204167_at NM_000060 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000060.1 /DEF=Homo sapiens biotinidase (BTD), mRNA. /FEA=mRNA /GEN=BTD /PROD=biotinidase precursor /DB_XREF=gi:4557372 /UG=Hs.78885 biotinidase /FL=gb:NM_000060.1 gb:U03274.1" NM_000060 biotinidase BTD 686 NM_000060 /// NM_001281723 /// NM_001281724 /// NM_001281725 /// NM_001281726 /// XM_005265417 /// XM_006713314 /// XM_006713315 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0043204 // perikaryon // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004075 // biotin carboxylase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0047708 // biotinidase activity // inferred from electronic annotation" 204168_at NM_002413 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002413.1 /DEF=Homo sapiens microsomal glutathione S-transferase 2 (MGST2), mRNA. /FEA=mRNA /GEN=MGST2 /PROD=microsomal glutathione S-transferase 2 /DB_XREF=gi:4505180 /UG=Hs.81874 microsomal glutathione S-transferase 2 /FL=gb:U77604.1 gb:NM_002413.1" NM_002413 microsomal glutathione S-transferase 2 MGST2 4258 NM_001204366 /// NM_001204367 /// NM_001204368 /// NM_002413 /// XM_006714221 0006691 // leukotriene metabolic process // inferred from electronic annotation /// 0006750 // glutathione biosynthetic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // not recorded /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 1901687 // glutathione derivative biosynthetic process // traceable author statement 0005635 // nuclear envelope // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004364 // glutathione transferase activity // inferred from direct assay /// 0004464 // leukotriene-C4 synthase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // not recorded /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204169_at NM_000883 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000883.1 /DEF=Homo sapiens IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), mRNA. /FEA=mRNA /GEN=IMPDH1 /PROD=IMP (inosine monophosphate) dehydrogenase 1 /DB_XREF=gi:4504686 /UG=Hs.850 IMP (inosine monophosphate) dehydrogenase 1 /FL=gb:J05272.1 gb:NM_000883.1" NM_000883 IMP (inosine 5'-monophosphate) dehydrogenase 1 IMPDH1 3614 NM_000883 /// NM_001102605 /// NM_001142573 /// NM_001142574 /// NM_001142575 /// NM_001142576 /// NM_183243 /// XM_005250313 /// XM_005250314 /// XM_006715967 /// XM_006715968 /// XM_006715969 /// XM_006715970 /// XM_006715971 /// XM_006715972 /// XM_006715973 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006177 // GMP biosynthetic process // inferred from electronic annotation /// 0009168 // purine ribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046651 // lymphocyte proliferation // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003938 // IMP dehydrogenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0018580 // nitronate monooxygenase activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204170_s_at NM_001827 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001827.1 /DEF=Homo sapiens CDC28 protein kinase 2 (CKS2), mRNA. /FEA=mRNA /GEN=CKS2 /PROD=CDC28 protein kinase 2 /DB_XREF=gi:4502858 /UG=Hs.83758 CDC28 protein kinase 2 /FL=gb:NM_001827.1" NM_001827 CDC28 protein kinase regulatory subunit 2 CKS2 1164 NM_001827 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007127 // meiosis I // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation 204171_at NM_003161 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003161.1 /DEF=Homo sapiens ribosomal protein S6 kinase, 70kD, polypeptide 1 (RPS6KB1), mRNA. /FEA=mRNA /GEN=RPS6KB1 /PROD=serinethreonine kinase 14 alpha /DB_XREF=gi:4506736 /UG=Hs.86858 ribosomal protein S6 kinase, 70kD, polypeptide 1 /FL=gb:M60724.1 gb:NM_003161.1" NM_003161 "ribosomal protein S6 kinase, 70kDa, polypeptide 1" RPS6KB1 6198 NM_001272042 /// NM_001272043 /// NM_001272044 /// NM_001272060 /// NM_003161 /// XM_006722009 /// XM_006722010 0000082 // G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0003009 // skeletal muscle contraction // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007616 // long-term memory // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014732 // skeletal muscle atrophy // inferred from electronic annotation /// 0014878 // response to electrical stimulus involved in regulation of muscle adaptation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0031929 // TOR signaling // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0034612 // response to tumor necrosis factor // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043201 // response to leucine // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045948 // positive regulation of translational initiation // inferred from mutant phenotype /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048633 // positive regulation of skeletal muscle tissue growth // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004711 // ribosomal protein S6 kinase activity // inferred from electronic annotation /// 0004712 // protein serine/threonine/tyrosine kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation" 204172_at NM_000097 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000097.1 /DEF=Homo sapiens coproporphyrinogen oxidase (coproporphyria, harderoporphyria) (CPO), mRNA. /FEA=mRNA /GEN=CPO /PROD=coproporphyrinogen oxidase (coproporphyria,harderoporphyria) /DB_XREF=gi:4503016 /UG=Hs.89866 coproporphyrinogen oxidase (coproporphyria, harderoporphyria) /FL=gb:NM_000097.1 gb:D16611.1" NM_000097 coproporphyrinogen oxidase CPOX 1371 NM_000097 /// XM_005247125 0006778 // porphyrin-containing compound metabolic process // traceable author statement /// 0006779 // porphyrin-containing compound biosynthetic process // inferred from electronic annotation /// 0006782 // protoporphyrinogen IX biosynthetic process // inferred from electronic annotation /// 0006783 // heme biosynthetic process // traceable author statement /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0017085 // response to insecticide // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // traceable author statement 0004109 // coproporphyrinogen oxidase activity // traceable author statement /// 0005212 // structural constituent of eye lens // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay 204173_at NM_002475 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002475.1 /DEF=Homo sapiens myosin, light polypeptide 1, alkali; skeletal, fast (MYL1), mRNA. /FEA=mRNA /GEN=MYL1 /PROD=myosin, light polypeptide 1, alkali; skeletal,fast /DB_XREF=gi:4505302 /UG=Hs.90318 myosin, light polypeptide 1, alkali; skeletal, fast /FL=gb:M31211.1 gb:NM_002475.1" NM_002475 "myosin, light chain 6B, alkali, smooth muscle and non-muscle" MYL6B 140465 NM_001199629 /// NM_002475 0006936 // muscle contraction // traceable author statement /// 0007519 // skeletal muscle tissue development // traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030049 // muscle filament sliding // traceable author statement 0005829 // cytosol // traceable author statement /// 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // traceable author statement /// 0016461 // unconventional myosin complex // traceable author statement 0003774 // motor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // traceable author statement 204174_at NM_001629 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001629.1 /DEF=Homo sapiens arachidonate 5-lipoxygenase-activating protein (ALOX5AP), mRNA. /FEA=mRNA /GEN=ALOX5AP /PROD=arachidonate 5-lipoxygenase-activating protein /DB_XREF=gi:4502058 /UG=Hs.100194 arachidonate 5-lipoxygenase-activating protein /FL=gb:NM_001629.1" NM_001629 arachidonate 5-lipoxygenase-activating protein ALOX5AP 241 NM_001204406 /// NM_001629 0002540 // leukotriene production involved in inflammatory response // inferred from electronic annotation /// 0002675 // positive regulation of acute inflammatory response // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0070207 // protein homotrimerization // inferred from physical interaction /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 2001300 // lipoxin metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0004364 // glutathione transferase activity // not recorded /// 0004464 // leukotriene-C4 synthase activity // not recorded /// 0004602 // glutathione peroxidase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050544 // arachidonic acid binding // inferred from direct assay 204175_at NM_015871 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015871.1 /DEF=Homo sapiens zinc finger protein (LOC51042), mRNA. /FEA=mRNA /GEN=LOC51042 /PROD=zinc finger protein /DB_XREF=gi:7705661 /UG=Hs.102419 zinc finger protein /FL=gb:BC002580.1 gb:D45213.1 gb:NM_015871.1" NM_015871 zinc finger protein 593 ZNF593 51042 NM_015871 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204176_at AA808694 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA808694 /FEA=EST /DB_XREF=gi:2878100 /DB_XREF=est:oa47b08.s1 /CLONE=IMAGE:1308087 /UG=Hs.106290 Kelch motif containing protein /FL=gb:NM_014458.2 gb:AB026190.1 AA808694 kelch-like family member 20 KLHL20 27252 NM_014458 /// XM_005245093 /// XM_006711277 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035455 // response to interferon-alpha // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 1990390 // protein K33-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019964 // interferon-gamma binding // inferred from direct assay 204177_s_at NM_014458 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014458.2 /DEF=Homo sapiens Kelch motif containing protein (AB026190), mRNA. /FEA=mRNA /GEN=AB026190 /PROD=Kelch motif containing protein /DB_XREF=gi:13677223 /UG=Hs.106290 Kelch motif containing protein /FL=gb:NM_014458.2 gb:AB026190.1" NM_014458 kelch-like family member 20 KLHL20 27252 NM_014458 /// XM_005245093 /// XM_006711277 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035455 // response to interferon-alpha // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043161 // proteasome-mediated ubiquitin-dependent protein catabolic process // inferred from direct assay /// 1990390 // protein K33-linked ubiquitination // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016605 // PML body // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031463 // Cul3-RING ubiquitin ligase complex // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019964 // interferon-gamma binding // inferred from direct assay 204178_s_at NM_006328 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006328.1 /DEF=Homo sapiens RNA binding motif protein 14 (RBM14), mRNA. /FEA=mRNA /GEN=RBM14 /PROD=RNA binding motif protein 14 /DB_XREF=gi:5454063 /UG=Hs.11170 RNA binding motif protein 14 /FL=gb:AF080561.1 gb:NM_006328.1" NM_006328 RNA binding motif protein 14 RBM14 10432 NM_001198836 /// NM_001198837 /// NM_006328 /// NM_032886 "0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // non-traceable author statement /// 0009725 // response to hormone // traceable author statement /// 0016575 // histone deacetylation // inferred from physical interaction /// 0030520 // intracellular estrogen receptor signaling pathway // non-traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0016592 // mediator complex // non-traceable author statement /// 0030529 // ribonucleoprotein complex // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement /// 0044822 // poly(A) RNA binding // inferred from direct assay" 204179_at NM_005368 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005368.1 /DEF=Homo sapiens myoglobin (MB), mRNA. /FEA=mRNA /GEN=MB /PROD=myoglobin /DB_XREF=gi:4885476 /UG=Hs.118836 myoglobin /FL=gb:NM_005368.1" NM_005368 myoglobin MB 4151 NM_005368 /// NM_203377 /// NM_203378 /// XM_005261605 0001666 // response to hypoxia // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009725 // response to hormone // inferred from electronic annotation /// 0015671 // oxygen transport // inferred from electronic annotation /// 0031444 // slow-twitch skeletal muscle fiber contraction // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204180_s_at AI745225 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI745225 /FEA=EST /DB_XREF=gi:5113513 /DB_XREF=est:wg10d12.x1 /CLONE=IMAGE:2364695 /UG=Hs.127649 KIAA0414 protein /FL=gb:NM_014007.1 AI745225 zinc finger and BTB domain containing 43 ZBTB43 23099 NM_001135776 /// NM_014007 /// XM_005251835 /// XM_005251836 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204181_s_at T90308 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:T90308 /FEA=EST /DB_XREF=gi:718821 /DB_XREF=est:ye16a03.s1 /CLONE=IMAGE:117868 /UG=Hs.127649 KIAA0414 protein /FL=gb:NM_014007.1 T90308 zinc finger and BTB domain containing 43 ZBTB43 23099 NM_001135776 /// NM_014007 /// XM_005251835 /// XM_005251836 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204182_s_at NM_014007 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014007.1 /DEF=Homo sapiens KIAA0414 protein (KIAA0414), mRNA. /FEA=mRNA /GEN=KIAA0414 /PROD=KIAA0414 protein /DB_XREF=gi:7662099 /UG=Hs.127649 KIAA0414 protein /FL=gb:NM_014007.1" NM_014007 zinc finger and BTB domain containing 43 ZBTB43 23099 NM_001135776 /// NM_014007 /// XM_005251835 /// XM_005251836 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204183_s_at AI478542 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI478542 /FEA=EST /DB_XREF=gi:4371768 /DB_XREF=est:tm53c11.x1 /CLONE=IMAGE:2161844 /UG=Hs.13944 adrenergic, beta, receptor kinase 2 /FL=gb:NM_005160.2" AI478542 "adrenergic, beta, receptor kinase 2" ADRBK2 157 NM_005160 /// XM_006724158 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation" 204184_s_at NM_005160 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005160.2 /DEF=Homo sapiens adrenergic, beta, receptor kinase 2 (ADRBK2), mRNA. /FEA=mRNA /GEN=ADRBK2 /PROD=beta adrenergic receptor kinase 2 /DB_XREF=gi:6138972 /UG=Hs.13944 adrenergic, beta, receptor kinase 2 /FL=gb:NM_005160.2" NM_005160 "adrenergic, beta, receptor kinase 2" ADRBK2 157 NM_005160 /// XM_006724158 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031623 // receptor internalization // inferred from direct assay /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation" 204185_x_at NM_005038 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005038.1 /DEF=Homo sapiens peptidylprolyl isomerase D (cyclophilin D) (PPID), mRNA. /FEA=mRNA /GEN=PPID /PROD=peptidylprolyl isomerase D (cyclophilin D) /DB_XREF=gi:4826931 /UG=Hs.143482 peptidylprolyl isomerase D (cyclophilin D) /FL=gb:L11667.1 gb:NM_005038.1" NM_005038 peptidylprolyl isomerase D PPID 5481 NM_005038 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019076 // viral release from host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from sequence or structural similarity /// 0030544 // Hsp70 protein binding // inferred from sequence or structural similarity /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 204186_s_at AI014573 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI014573 /FEA=EST /DB_XREF=gi:3228954 /DB_XREF=est:ou40h11.x1 /CLONE=IMAGE:1628805 /UG=Hs.143482 peptidylprolyl isomerase D (cyclophilin D) /FL=gb:L11667.1 gb:NM_005038.1 AI014573 peptidylprolyl isomerase D PPID 5481 NM_005038 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006457 // protein folding // inferred from sequence or structural similarity /// 0006461 // protein complex assembly // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019076 // viral release from host cell // traceable author statement /// 0034389 // lipid particle organization // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0050714 // positive regulation of protein secretion // inferred from mutant phenotype /// 0061077 // chaperone-mediated protein folding // inferred from direct assay /// 0071492 // cellular response to UV-A // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030331 // estrogen receptor binding // inferred from sequence or structural similarity /// 0030544 // Hsp70 protein binding // inferred from sequence or structural similarity /// 0031072 // heat shock protein binding // inferred from physical interaction /// 0042277 // peptide binding // inferred from electronic annotation /// 0051879 // Hsp90 protein binding // inferred from direct assay 204187_at NM_006877 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006877.1 /DEF=Homo sapiens guanosine monophosphate reductase (GMPR), mRNA. /FEA=mRNA /GEN=GMPR /PROD=guanosine monophosphate reductase /DB_XREF=gi:11321610 /UG=Hs.1435 guanosine monophosphate reductase /FL=gb:NM_006877.1 gb:M24470.1" NM_006877 guanosine monophosphate reductase GMPR 2766 NM_006877 0006144 // purine nucleobase metabolic process // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 1902560 // GMP reductase complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003920 // GMP reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204188_s_at M57707 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M57707.1 /DEF=Human retinoic acid receptor gamma mRNA, complete cds. /FEA=mRNA /GEN=RARG /PROD=retinoic acid receptor-gamma /DB_XREF=gi:190867 /UG=Hs.1497 retinoic acid receptor, gamma /FL=gb:M24857.1 gb:M57707.1 gb:M38258.1 gb:NM_000966.1" M57707 "retinoic acid receptor, gamma" RARG 5916 NM_000966 /// NM_001042728 /// NM_001243730 /// NM_001243731 /// NM_001243732 /// XM_005269054 /// XM_005269055 /// XM_005269056 /// XM_005269057 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0003430 // growth plate cartilage chondrocyte growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043068 // positive regulation of programmed cell death // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // traceable author statement /// 0060173 // limb development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060429 // epithelium development // inferred from electronic annotation /// 0060534 // trachea cartilage development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070384 // Harderian gland development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from sequence or structural similarity 204189_at NM_000966 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000966.1 /DEF=Homo sapiens retinoic acid receptor, gamma (RARG), mRNA. /FEA=mRNA /GEN=RARG /PROD=retinoic acid receptor, gamma /DB_XREF=gi:4506422 /UG=Hs.1497 retinoic acid receptor, gamma /FL=gb:M24857.1 gb:M57707.1 gb:M38258.1 gb:NM_000966.1" NM_000966 "retinoic acid receptor, gamma" RARG 5916 NM_000966 /// NM_001042728 /// NM_001243730 /// NM_001243731 /// NM_001243732 /// XM_005269054 /// XM_005269055 /// XM_005269056 /// XM_005269057 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0003430 // growth plate cartilage chondrocyte growth // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // traceable author statement /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032331 // negative regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from direct assay /// 0035116 // embryonic hindlimb morphogenesis // inferred from sequence or structural similarity /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043068 // positive regulation of programmed cell death // inferred from sequence or structural similarity /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045596 // negative regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from direct assay /// 0048608 // reproductive structure development // inferred from electronic annotation /// 0048732 // gland development // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // traceable author statement /// 0060173 // limb development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060429 // epithelium development // inferred from electronic annotation /// 0060534 // trachea cartilage development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0061037 // negative regulation of cartilage development // inferred from electronic annotation /// 0070384 // Harderian gland development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from sequence or structural similarity 204190_at NM_005800 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005800.1 /DEF=Homo sapiens highly charged protein (D13S106E), mRNA. /FEA=mRNA /GEN=D13S106E /PROD=highly charged protein /DB_XREF=gi:5031648 /UG=Hs.151236 highly charged protein /FL=gb:NM_005800.1" NM_005800 ubiquitin specific peptidase like 1 USPL1 10208 NM_005800 /// XM_005266213 /// XM_005266214 /// XM_006719751 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0016926 // protein desumoylation // inferred from direct assay /// 0030576 // Cajal body organization // inferred from mutant phenotype 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032183 // SUMO binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from direct assay /// 0070140 // SUMO-specific isopeptidase activity // inferred from direct assay 204191_at NM_000629 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000629.1 /DEF=Homo sapiens interferon (alpha, beta and omega) receptor 1 (IFNAR1), mRNA. /FEA=mRNA /GEN=IFNAR1 /PROD=interferon (alpha, beta and omega) receptor 1 /DB_XREF=gi:10835182 /UG=Hs.1513 interferon (alpha, beta and omega) receptor 1 /FL=gb:NM_000629.1 gb:J03171.1" NM_000629 "interferon (alpha, beta and omega) receptor 1" IFNAR1 3454 NM_000629 /// XM_005260964 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0042110 // T cell activation // inferred from electronic annotation /// 0045351 // type I interferon biosynthetic process // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004904 // interferon receptor activity // inferred from electronic annotation /// 0004905 // type I interferon receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204192_at NM_001774 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001774.1 /DEF=Homo sapiens CD37 antigen (CD37), mRNA. /FEA=mRNA /GEN=CD37 /PROD=CD37 antigen /DB_XREF=gi:4502662 /UG=Hs.153053 CD37 antigen /FL=gb:NM_001774.1" NM_001774 CD37 molecule CD37 951 NM_001040031 /// NM_001774 /// XM_005259435 /// XM_005259436 /// XM_006723511 "0001570 // vasculogenesis // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0002639 // positive regulation of immunoglobulin production // inferred from electronic annotation /// 0002920 // regulation of humoral immune response // inferred from electronic annotation /// 0003143 // embryonic heart tube morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030886 // negative regulation of myeloid dendritic cell activation // inferred from electronic annotation /// 0030903 // notochord development // inferred from electronic annotation /// 0035329 // hippo signaling // inferred from direct assay /// 0035329 // hippo signaling // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048339 // paraxial mesoderm development // inferred from electronic annotation /// 0048368 // lateral mesoderm development // inferred from electronic annotation /// 0050688 // regulation of defense response to virus // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation" 0001772 // immunological synapse // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204193_at NM_005198 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005198.2 /DEF=Homo sapiens choline kinase-like (CHKL), mRNA. /FEA=mRNA /GEN=CHKL /PROD=choline kinase-like /DB_XREF=gi:6978648 /UG=Hs.154886 choline kinase-like /FL=gb:AB029886.1 gb:NM_005198.2" NM_005198 choline kinase beta CHKB 1120 NM_005198 /// NM_152253 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from direct assay /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004095 // carnitine O-palmitoyltransferase activity // inferred from electronic annotation /// 0004095 // carnitine O-palmitoyltransferase activity // traceable author statement /// 0004103 // choline kinase activity // inferred from direct assay /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 204194_at NM_001186 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001186.1 /DEF=Homo sapiens BTB and CNC homology 1, basic leucine zipper transcription factor 1 (BACH1), mRNA. /FEA=mRNA /GEN=BACH1 /PROD=BTB and CNC homology 1, basic leucine zippertranscription factor 1 /DB_XREF=gi:4502352 /UG=Hs.154276 BTB and CNC homology 1, basic leucine zipper transcription factor 1 /FL=gb:AB002803.1 gb:NM_001186.1" NM_001186 "BTB and CNC homology 1, basic leucine zipper transcription factor 1" BACH1 571 NM_001011545 /// NM_001186 /// NM_206866 /// NR_027655 /// XM_005261012 /// XM_005261013 /// XM_005261014 /// XM_006724034 /// XR_430352 /// XR_430353 /// XR_430354 "0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // inferred from mutant phenotype /// 0000117 // regulation of transcription involved in G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0061418 // regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0020037 // heme binding // non-traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204195_s_at AL570914 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL570914 /FEA=EST /DB_XREF=gi:12927687 /DB_XREF=est:AL570914 /CLONE=CS0DI013YK18 (3 prime) /UG=Hs.158225 PBXknotted 1 homeobox 1 /FL=gb:U68727.1 gb:NM_004571.1 AL570914 PBX/knotted 1 homeobox 1 PKNOX1 5316 NM_001286258 /// NM_004571 "0001525 // angiogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204196_x_at NM_004571 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004571.1 /DEF=Homo sapiens PBXknotted 1 hoemobox 1 (PKNOX1), mRNA. /FEA=mRNA /GEN=PKNOX1 /PROD=PBXknotted 1 hoemobox 1 /DB_XREF=gi:4758929 /UG=Hs.158225 PBXknotted 1 homeobox 1 /FL=gb:U68727.1 gb:NM_004571.1" NM_004571 PBX/knotted 1 homeobox 1 PKNOX1 5316 NM_001286258 /// NM_004571 "0001525 // angiogenesis // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0043010 // camera-type eye development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 204197_s_at NM_004350 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004350.1 /DEF=Homo sapiens runt-related transcription factor 3 (RUNX3), mRNA. /FEA=mRNA /GEN=RUNX3 /PROD=runt-related transcription factor 3 /DB_XREF=gi:4757917 /UG=Hs.170019 runt-related transcription factor 3 /FL=gb:NM_004350.1" NM_004350 runt-related transcription factor 3 RUNX3 864 NM_001031680 /// NM_004350 /// XM_005246024 /// XM_006711016 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007411 // axon guidance // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement 204198_s_at AA541630 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA541630 /FEA=EST /DB_XREF=gi:2288064 /DB_XREF=est:ni99e01.s1 /CLONE=IMAGE:984984 /UG=Hs.170019 runt-related transcription factor 3 /FL=gb:NM_004350.1 AA541630 runt-related transcription factor 3 RUNX3 864 NM_001031680 /// NM_004350 /// XM_005246024 /// XM_006711016 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007411 // axon guidance // inferred from electronic annotation /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0032609 // interferon-gamma production // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0050680 // negative regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // non-traceable author statement 204199_at NM_014636 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014636.1 /DEF=Homo sapiens Ral guanine nucleotide exchange factor RalGPS1A (RalGPS1A), mRNA. /FEA=mRNA /GEN=RalGPS1A /PROD=Ral guanine nucleotide exchange factor RalGPS1A /DB_XREF=gi:7662069 /UG=Hs.170307 Ral guanine nucleotide exchange factor RalGPS1A /FL=gb:AB002349.1 gb:NM_014636.1" NM_014636 Ral GEF with PH domain and SH3 binding motif 1 RALGPS1 9649 NM_001190728 /// NM_001190729 /// NM_001190730 /// NM_014636 /// XM_005252318 /// XM_006717327 /// XM_006717328 /// XM_006717329 /// XM_006717330 /// XM_006717331 /// XM_006717332 /// XM_006717333 /// XM_006717334 /// XM_006717335 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032315 // regulation of Ral GTPase activity // inferred from direct assay /// 0032485 // regulation of Ral protein signal transduction // inferred from direct assay /// 0032852 // positive regulation of Ral GTPase activity // inferred from direct assay /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0043087 // regulation of GTPase activity // non-traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // non-traceable author statement /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008321 // Ral guanyl-nucleotide exchange factor activity // inferred from direct assay 204200_s_at NM_002608 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002608.1 /DEF=Homo sapiens platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) (PDGFB), mRNA. /FEA=mRNA /GEN=PDGFB /PROD=platelet-derived growth factor beta polypeptide(simian sarcoma viral (v-sis) oncogene homolog) /DB_XREF=gi:4505680 /UG=Hs.1976 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) /FL=gb:M12783.1 gb:NM_002608.1" NM_002608 platelet-derived growth factor beta polypeptide PDGFB 5155 NM_002608 /// NM_033016 "0001568 // blood vessel development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from sequence or structural similarity /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0002576 // platelet degranulation // traceable author statement /// 0003104 // positive regulation of glomerular filtration // inferred from sequence or structural similarity /// 0006260 // DNA replication // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006929 // substrate-dependent cell migration // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009611 // response to wounding // inferred from direct assay /// 0009611 // response to wounding // non-traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010512 // negative regulation of phosphatidylinositol biosynthetic process // inferred from direct assay /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from direct assay /// 0016049 // cell growth // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from mutant phenotype /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0031954 // positive regulation of protein autophosphorylation // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032148 // activation of protein kinase B activity // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035793 // positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway // inferred from direct assay /// 0038001 // paracrine signaling // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from direct assay /// 0045743 // positive regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048146 // positive regulation of fibroblast proliferation // inferred from direct assay /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050730 // regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0050918 // positive chemotaxis // inferred from direct assay /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060445 // branching involved in salivary gland morphogenesis // inferred from electronic annotation /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from electronic annotation /// 0061098 // positive regulation of protein tyrosine kinase activity // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0071363 // cellular response to growth factor stimulus // inferred from direct assay /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0072126 // positive regulation of glomerular mesangial cell proliferation // inferred from direct assay /// 0072255 // metanephric glomerular mesangial cell development // inferred from sequence or structural similarity /// 0072262 // metanephric glomerular mesangial cell proliferation involved in metanephros development // inferred from electronic annotation /// 0072264 // metanephric glomerular endothelium development // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from mutant phenotype /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 1900127 // positive regulation of hyaluronan biosynthetic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from direct assay /// 2000573 // positive regulation of DNA biosynthetic process // inferred from direct assay /// 2000591 // positive regulation of metanephric mesenchymal cell migration // inferred from direct assay" 0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement 0005161 // platelet-derived growth factor receptor binding // inferred from direct assay /// 0005161 // platelet-derived growth factor receptor binding // inferred from physical interaction /// 0005161 // platelet-derived growth factor receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008083 // growth factor activity // inferred from direct assay /// 0016176 // superoxide-generating NADPH oxidase activator activity // inferred from direct assay /// 0042056 // chemoattractant activity // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from physical interaction 204201_s_at NM_006264 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006264.1 /DEF=Homo sapiens protein tyrosine phosphatase, non-receptor type 13 (APO-1CD95 (Fas)-associated phosphatase) (PTPN13), mRNA. /FEA=mRNA /GEN=PTPN13 /PROD=protein tyrosine phosphatase, non-receptor type13 (APO-1CD95 (Fas)-associated phosphatase) /DB_XREF=gi:5453991 /UG=Hs.211595 protein tyrosine phosphatase, non-receptor type 13 (APO-1CD95 (Fas)-associated phosphatase) /FL=gb:D21210.1 gb:NM_006264.1" NM_006264 "protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)" PTPN13 5783 NM_006264 /// NM_080683 /// NM_080684 /// NM_080685 /// XM_005263167 0006470 // protein dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 204202_at NM_017604 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_017604.1 /DEF=Homo sapiens KIAA1023 protein (KIAA1023), mRNA. /FEA=mRNA /GEN=KIAA1023 /PROD=hypothetical protein DKFZp434I0118 /DB_XREF=gi:8922140 /UG=Hs.21361 KIAA1023 protein /FL=gb:NM_017604.1" NM_017604 IQ motif containing E IQCE 23288 NM_001100390 /// NM_001287499 /// NM_001287500 /// NM_001287501 /// NM_001287502 /// NM_152558 /// XM_006715676 /// XM_006715677 /// XR_242067 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204203_at NM_001806 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001806.1 /DEF=Homo sapiens CCAATenhancer binding protein (CEBP), gamma (CEBPG), mRNA. /FEA=mRNA /GEN=CEBPG /PROD=CCAATenhancer binding protein gamma /DB_XREF=gi:4502768 /UG=Hs.2227 CCAATenhancer binding protein (CEBP), gamma /FL=gb:NM_001806.1 gb:U20240.1" NM_001806 "CCAAT/enhancer binding protein (C/EBP), gamma" CEBPG 1054 NM_001252296 /// NM_001806 "0001889 // liver development // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006955 // immune response // inferred from sequence or structural similarity /// 0016071 // mRNA metabolic process // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0042267 // natural killer cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0043353 // enucleate erythrocyte differentiation // inferred from sequence or structural similarity /// 0043388 // positive regulation of DNA binding // traceable author statement /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0045078 // positive regulation of interferon-gamma biosynthetic process // inferred from sequence or structural similarity /// 0045739 // positive regulation of DNA repair // inferred from expression pattern /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 204204_at NM_001860 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001860.1 /DEF=Homo sapiens solute carrier family 31 (copper transporters), member 2 (SLC31A2), mRNA. /FEA=mRNA /GEN=SLC31A2 /PROD=solute carrier family 31 (copper transporters),member 2 /DB_XREF=gi:4507016 /UG=Hs.24030 solute carrier family 31 (copper transporters), member 2 /FL=gb:U83461.1 gb:NM_001860.1" NM_001860 "solute carrier family 31 (copper transporter), member 2" SLC31A2 1318 NM_001860 /// XM_006716951 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006825 // copper ion transport // traceable author statement /// 0035434 // copper ion transmembrane transport // inferred from electronic annotation 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005375 // copper ion transmembrane transporter activity // inferred from electronic annotation 204205_at NM_021822 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021822.1 /DEF=Homo sapiens phorbolin-like protein MDS019 (MDS019), mRNA. /FEA=mRNA /GEN=MDS019 /PROD=phorbolin-like protein MDS019 /DB_XREF=gi:13399303 /UG=Hs.250619 phorbolin-like protein MDS019 /FL=gb:AF182420.1 gb:NM_021822.1" NM_021822 "apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G" APOBEC3G 60489 NM_021822 /// XM_006724290 0002230 // positive regulation of defense response to virus by host // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009972 // cytidine deamination // inferred from direct assay /// 0010529 // negative regulation of transposition // inferred from direct assay /// 0016032 // viral process // traceable author statement /// 0016553 // base conversion or substitution editing // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045071 // negative regulation of viral genome replication // inferred from direct assay /// 0045087 // innate immune response // inferred from direct assay /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0048525 // negative regulation of viral process // inferred from direct assay /// 0051607 // defense response to virus // inferred from direct assay /// 0070383 // DNA cytosine deamination // inferred from direct assay 0000932 // cytoplasmic mRNA processing body // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0030895 // apolipoprotein B mRNA editing enzyme complex // traceable author statement "0003723 // RNA binding // inferred from direct assay /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004126 // cytidine deaminase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016814 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047844 // deoxycytidine deaminase activity // inferred from direct assay" 204206_at NM_020310 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020310.1 /DEF=Homo sapiens MAX binding protein (MNT), mRNA. /FEA=mRNA /GEN=MNT /PROD=MAX binding protein /DB_XREF=gi:9945317 /UG=Hs.25497 MAX binding protein /FL=gb:NM_020310.1" NM_020310 MAX network transcriptional repressor MNT 4335 NM_020310 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0001227 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 204207_s_at AB012142 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB012142.1 /DEF=Homo sapiens hCAP1a mRNA for mRNA capping enzyme, complete cds. /FEA=mRNA /GEN=hCAP1a /PROD=mRNA capping enzyme /DB_XREF=gi:2979495 /UG=Hs.27345 RNA guanylyltransferase and 5-phosphatase /FL=gb:AF025654.1 gb:AB012142.1 gb:AB009022.1 gb:NM_003800.1" AB012142 RNA guanylyltransferase and 5'-phosphatase RNGTT 8732 NM_001286426 /// NM_001286428 /// NM_003800 /// XM_006715589 /// XR_427976 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0098507 // polynucleotide 5' dephosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004484 // mRNA guanylyltransferase activity // inferred from direct assay /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008192 // RNA guanylyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050355 // triphosphatase activity // inferred from direct assay 204208_at NM_003800 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003800.1 /DEF=Homo sapiens RNA guanylyltransferase and 5-phosphatase (RNGTT), mRNA. /FEA=mRNA /GEN=RNGTT /PROD=RNA guanylyltransferase and 5-phosphatase /DB_XREF=gi:4506562 /UG=Hs.27345 RNA guanylyltransferase and 5-phosphatase /FL=gb:AF025654.1 gb:AB012142.1 gb:AB009022.1 gb:NM_003800.1" NM_003800 RNA guanylyltransferase and 5'-phosphatase RNGTT 8732 NM_001286426 /// NM_001286428 /// NM_003800 /// XM_006715589 /// XR_427976 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006370 // 7-methylguanosine mRNA capping // inferred from direct assay /// 0006370 // 7-methylguanosine mRNA capping // traceable author statement /// 0006396 // RNA processing // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0098507 // polynucleotide 5' dephosphorylation // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004484 // mRNA guanylyltransferase activity // inferred from direct assay /// 0004651 // polynucleotide 5'-phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0008192 // RNA guanylyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0050355 // triphosphatase activity // inferred from direct assay 204209_at AI638771 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AI638771 /FEA=EST /DB_XREF=gi:4691005 /DB_XREF=est:tt32b06.x1 /CLONE=IMAGE:2242451 /UG=Hs.273558 phosphate cytidylyltransferase 1, choline, alpha isoform /FL=gb:NM_005017.1 gb:L28957.1" AI638771 "phosphate cytidylyltransferase 1, choline, alpha" PCYT1A 5130 NM_005017 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from sequence or structural similarity /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004105 // choline-phosphate cytidylyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 204210_s_at NM_005017 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005017.1 /DEF=Homo sapiens phosphate cytidylyltransferase 1, choline, alpha isoform (PCYT1A), mRNA. /FEA=mRNA /GEN=PCYT1A /PROD=phosphate cytidylyltransferase 1, choline, alphaisoform /DB_XREF=gi:4826887 /UG=Hs.273558 phosphate cytidylyltransferase 1, choline, alpha isoform /FL=gb:NM_005017.1 gb:L28957.1" NM_005017 "phosphate cytidylyltransferase 1, choline, alpha" PCYT1A 5130 NM_005017 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from sequence or structural similarity /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0009628 // response to abiotic stimulus // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0042587 // glycogen granule // inferred from sequence or structural similarity 0003824 // catalytic activity // inferred from electronic annotation /// 0004105 // choline-phosphate cytidylyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation 204211_x_at NM_002759 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002759.1 /DEF=Homo sapiens protein kinase, interferon-inducible double stranded RNA dependent (PRKR), mRNA. /FEA=mRNA /GEN=PRKR /PROD=protein kinase, interferon-inducible doublestranded RNA dependent /DB_XREF=gi:4506102 /UG=Hs.274382 protein kinase, interferon-inducible double stranded RNA dependent /FL=gb:M35663.1 gb:M85294.1 gb:NM_002759.1" NM_002759 eukaryotic translation initiation factor 2-alpha kinase 2 EIF2AK2 5610 NM_001135651 /// NM_001135652 /// NM_002759 "0000186 // activation of MAPKK activity // inferred from mutant phenotype /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0030683 // evasion or tolerance by virus of host immune response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 1900225 // regulation of NLRP3 inflammasome complex assembly // inferred from sequence or structural similarity /// 1901224 // positive regulation of NIK/NF-kappaB signaling // inferred from sequence or structural similarity /// 1901532 // regulation of hematopoietic progenitor cell differentiation // inferred from sequence or structural similarity /// 1902033 // regulation of hematopoietic stem cell proliferation // inferred from sequence or structural similarity /// 1902036 // regulation of hematopoietic stem cell differentiation // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from mutant phenotype /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay" 204212_at NM_005469 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005469.1 /DEF=Homo sapiens peroxisomal acyl-CoA thioesterase (PTE1), mRNA. /FEA=mRNA /GEN=PTE1 /PROD=peroxisomal acyl-CoA thioesterase /DB_XREF=gi:4885564 /UG=Hs.283476 peroxisomal acyl-CoA thioesterase /FL=gb:AF014404.1 gb:AF124264.1 gb:NM_005469.1" NM_005469 acyl-CoA thioesterase 8 ACOT8 10005 NM_005469 /// NM_183385 /// NM_183386 /// XM_005260239 /// XM_005260240 /// XR_244130 0006637 // acyl-CoA metabolic process // inferred from direct assay /// 0006699 // bile acid biosynthetic process // traceable author statement /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016559 // peroxisome fission // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0033559 // unsaturated fatty acid metabolic process // traceable author statement /// 0036109 // alpha-linolenic acid metabolic process // traceable author statement /// 0043649 // dicarboxylic acid catabolic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005782 // peroxisomal matrix // inferred from direct assay /// 0005782 // peroxisomal matrix // inferred from mutant phenotype /// 0005782 // peroxisomal matrix // traceable author statement 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0033882 // choloyl-CoA hydrolase activity // inferred from electronic annotation /// 0047617 // acyl-CoA hydrolase activity // inferred from direct assay /// 0052815 // medium-chain acyl-CoA hydrolase activity // inferred from direct assay 204213_at NM_002644 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002644.1 /DEF=Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA. /FEA=mRNA /GEN=PIGR /PROD=polymeric immunoglobulin receptor /DB_XREF=gi:11342673 /UG=Hs.288579 polymeric immunoglobulin receptor /FL=gb:NM_002644.1" NM_002644 polymeric immunoglobulin receptor PIGR 5284 NM_002644 /// XM_005273163 0001580 // detection of chemical stimulus involved in sensory perception of bitter taste // inferred from direct assay /// 0001895 // retina homeostasis // inferred from expression pattern /// 0002415 // immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0038093 // Fc receptor signaling pathway // inferred from direct assay /// 0043113 // receptor clustering // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0001792 // polymeric immunoglobulin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 204214_s_at NM_006834 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006834.1 /DEF=Homo sapiens RAB32, member RAS oncogene family (RAB32), mRNA. /FEA=mRNA /GEN=RAB32 /PROD=RAB32, member RAS oncogene family /DB_XREF=gi:5803132 /UG=Hs.32217 RAB32, member RAS oncogene family /FL=gb:U71127.1 gb:NM_006834.1" NM_006834 "RAB32, member RAS oncogene family" RAB32 10981 NM_006834 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0032438 // melanosome organization // inferred from mutant phenotype /// 0035646 // endosome to melanosome transport // inferred from mutant phenotype /// 0090382 // phagosome maturation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030670 // phagocytic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031905 // early endosome lumen // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0045335 // phagocytic vesicle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // non-traceable author statement /// 0030742 // GTP-dependent protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from physical interaction /// 0035612 // AP-2 adaptor complex binding // inferred from direct assay /// 0035650 // AP-1 adaptor complex binding // inferred from physical interaction /// 0035651 // AP-3 adaptor complex binding // inferred from physical interaction 204215_at NM_024315 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024315.1 /DEF=Homo sapiens hypothetical protein MGC4175 (MGC4175), mRNA. /FEA=mRNA /GEN=MGC4175 /PROD=hypothetical protein MGC4175 /DB_XREF=gi:13236556 /UG=Hs.322404 hypothetical protein MGC4175 /FL=gb:BC002837.1 gb:NM_024315.1" NM_024315 "transmembrane protein 243, mitochondrial" TMEM243 79161 NM_024315 /// XM_005250585 /// XM_005250586 /// XM_005250587 /// XM_005250588 /// XM_005250589 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204216_s_at NM_024824 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024824.1 /DEF=Homo sapiens hypothetical protein FLJ11806 (FLJ11806), mRNA. /FEA=mRNA /GEN=FLJ11806 /PROD=hypothetical protein FLJ11806 /DB_XREF=gi:13376221 /UG=Hs.323443 hypothetical protein FLJ11806 /FL=gb:NM_024824.1" NM_024824 zinc finger CCCH-type containing 14 ZC3H14 79882 NM_001160103 /// NM_001160104 /// NM_024824 /// NM_207660 /// NM_207661 /// NM_207662 /// XM_005268067 /// XM_005268068 /// XM_005268069 /// XM_005268070 /// XM_005268071 /// XM_005268073 /// XM_006720257 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204217_s_at NM_005619 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005619.1 /DEF=Homo sapiens reticulon 2 (RTN2), mRNA. /FEA=mRNA /GEN=RTN2 /PROD=reticulon 2 /DB_XREF=gi:5032054 /UG=Hs.3803 reticulon 2 /FL=gb:AF004222.1 gb:AF004224.1 gb:NM_005619.1" NM_005619 reticulon 2 RTN2 6253 NM_005619 /// NM_206900 /// NM_206901 /// NM_206902 /// XR_243948 0007165 // signal transduction // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0046324 // regulation of glucose import // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0014802 // terminal cisterna // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // non-traceable author statement /// 0030315 // T-tubule // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204218_at NM_014042 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014042.1 /DEF=Homo sapiens DKFZP564M082 protein (DKFZP564M082), mRNA. /FEA=mRNA /GEN=DKFZP564M082 /PROD=DKFZP564M082 protein /DB_XREF=gi:7661621 /UG=Hs.38044 DKFZP564M082 protein /FL=gb:BC005156.1 gb:BC005393.1 gb:AF077206.1 gb:AL080071.1 gb:NM_014042.1" NM_014042 anaphase promoting complex subunit 15 ANAPC15 25906 NM_001278485 /// NM_001278486 /// NM_001278487 /// NM_001278488 /// NM_001278489 /// NM_001278490 /// NM_001278491 /// NM_001278492 /// NM_001278493 /// NM_001278494 /// NM_014042 /// XM_005273885 /// XM_005273886 /// XM_005273887 /// XM_005273888 /// XM_006718492 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype 0005622 // intracellular // inferred from direct assay /// 0005680 // anaphase-promoting complex // inferred from direct assay 204219_s_at NM_002802 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002802.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 1 (PSMC1), mRNA. /FEA=mRNA /GEN=PSMC1 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 1 /DB_XREF=gi:4506206 /UG=Hs.4745 proteasome (prosome, macropain) 26S subunit, ATPase, 1 /FL=gb:L02426.1 gb:NM_002802.1" NM_002802 "proteasome (prosome, macropain) 26S subunit, ATPase, 1" PSMC1 5700 NM_002802 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement" 0000502 // proteasome complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022624 // proteasome accessory complex // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0009378 // four-way junction helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0017025 // TBP-class protein binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204220_at NM_004877 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004877.1 /DEF=Homo sapiens glia maturation factor, gamma (GMFG), mRNA. /FEA=mRNA /GEN=GMFG /PROD=glia maturation factor, gamma /DB_XREF=gi:4758439 /UG=Hs.5210 glia maturation factor, gamma /FL=gb:AB001993.1 gb:AF038956.1 gb:NM_004877.1" NM_004877 "glia maturation factor, gamma" GMFG 9535 NM_004877 /// XM_005259440 0006468 // protein phosphorylation // traceable author statement /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005622 // intracellular // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004860 // protein kinase inhibitor activity // traceable author statement /// 0008047 // enzyme activator activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation 204221_x_at U16307 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:U16307.1 /DEF=Human glioma pathogenesis-related protein (GliPR) mRNA, complete cds. /FEA=mRNA /GEN=GliPR /PROD=glioma pathogenesis-related protein /DB_XREF=gi:1100927 /UG=Hs.64639 glioma pathogenesis-related protein /FL=gb:U16307.1 gb:NM_006851.1" U16307 GLI pathogenesis-related 1 GLIPR1 11010 NM_006851 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204222_s_at NM_006851 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006851.1 /DEF=Homo sapiens glioma pathogenesis-related protein (RTVP1), mRNA. /FEA=mRNA /GEN=RTVP1 /PROD=glioma pathogenesis-related protein /DB_XREF=gi:5803150 /UG=Hs.64639 glioma pathogenesis-related protein /FL=gb:U16307.1 gb:NM_006851.1" NM_006851 GLI pathogenesis-related 1 GLIPR1 11010 NM_006851 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 204223_at NM_002725 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002725.1 /DEF=Homo sapiens proline arginine-rich end leucine-rich repeat protein (PRELP), mRNA. /FEA=mRNA /GEN=PRELP /PROD=proline arginine-rich end leucine-rich repeatprotein /DB_XREF=gi:4506040 /UG=Hs.76494 proline arginine-rich end leucine-rich repeat protein /FL=gb:NM_002725.1 gb:U29089.1" NM_002725 proline/arginine-rich end leucine-rich repeat protein PRELP 5549 NM_002725 /// NM_201348 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 204224_s_at NM_000161 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000161.1 /DEF=Homo sapiens GTP cyclohydrolase 1 (dopa-responsive dystonia) (GCH1), mRNA. /FEA=mRNA /GEN=GCH1 /PROD=GTP cyclohydrolase 1 (dopa-responsive dystonia) /DB_XREF=gi:4503948 /UG=Hs.86724 GTP cyclohydrolase 1 (dopa-responsive dystonia) /FL=gb:NM_000161.1 gb:U66097.1 gb:U19523.1" NM_000161 GTP cyclohydrolase 1 GCH1 2643 NM_000161 /// NM_001024024 /// NM_001024070 /// NM_001024071 /// XM_005267530 "0006184 // GTP catabolic process // inferred from direct assay /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from direct assay /// 0006729 // tetrahydrobiopterin biosynthetic process // inferred from mutant phenotype /// 0006809 // nitric oxide biosynthetic process // non-traceable author statement /// 0008152 // metabolic process // inferred from direct assay /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0014916 // regulation of lung blood pressure // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0035998 // 7,8-dihydroneopterin 3'-triphosphate biosynthetic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042416 // dopamine biosynthetic process // inferred from direct assay /// 0042559 // pteridine-containing compound biosynthetic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0046209 // nitric oxide metabolic process // traceable author statement /// 0046654 // tetrahydrofolate biosynthetic process // inferred from electronic annotation /// 0048265 // response to pain // inferred from sequence or structural similarity /// 0050884 // neuromuscular process controlling posture // inferred from mutant phenotype /// 0050999 // regulation of nitric-oxide synthase activity // traceable author statement /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from mutant phenotype /// 0051066 // dihydrobiopterin metabolic process // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003934 // GTP cyclohydrolase I activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 204225_at NM_006037 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006037.2 /DEF=Homo sapiens histone deacetylase 4 (HDAC4), mRNA. /FEA=mRNA /GEN=HDAC4 /PROD=histone deacetylase 4 /DB_XREF=gi:13259519 /UG=Hs.91400 histone deacetylase 4 /FL=gb:NM_006037.2 gb:AF132607.1" NM_006037 histone deacetylase 4 HDAC4 9759 NM_006037 /// XM_006712877 /// XM_006712878 /// XM_006712879 /// XM_006712880 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010832 // negative regulation of myotube differentiation // inferred from mutant phenotype /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from electronic annotation /// 0014894 // response to denervation involved in regulation of muscle adaptation // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from direct assay /// 0016575 // histone deacetylation // inferred from mutant phenotype /// 0030183 // B cell differentiation // traceable author statement /// 0033235 // positive regulation of protein sumoylation // inferred from direct assay /// 0034983 // peptidyl-lysine deacetylation // inferred from direct assay /// 0042113 // B cell activation // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0045668 // negative regulation of osteoblast differentiation // inferred from electronic annotation /// 0045820 // negative regulation of glycolytic process // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048742 // regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051153 // regulation of striated muscle cell differentiation // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from mutant phenotype /// 0070932 // histone H3 deacetylation // inferred from direct assay /// 0070933 // histone H4 deacetylation // inferred from direct assay" 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0031672 // A band // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001047 // core promoter binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from direct assay /// 0031078 // histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032041 // NAD-dependent histone deacetylase activity (H3-K14 specific) // inferred from electronic annotation /// 0032129 // histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0033558 // protein deacetylase activity // inferred from direct assay /// 0033613 // activating transcription factor binding // inferred from physical interaction /// 0034739 // histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046969 // NAD-dependent histone deacetylase activity (H3-K9 specific) // inferred from electronic annotation /// 0046970 // NAD-dependent histone deacetylase activity (H4-K16 specific) // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from physical interaction /// 0097372 // NAD-dependent histone deacetylase activity (H3-K18 specific) // inferred from electronic annotation 204226_at NM_014393 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014393.1 /DEF=Homo sapiens staufen (Drosophila, RNA-binding protein) homolog 2 (STAU2), mRNA. /FEA=mRNA /GEN=STAU2 /PROD=staufen homolog 2 /DB_XREF=gi:7657624 /UG=Hs.96870 staufen (Drosophila, RNA-binding protein) homolog 2 /FL=gb:NM_014393.1" NM_014393 staufen double-stranded RNA binding protein 2 STAU2 27067 NM_001164380 /// NM_001164381 /// NM_001164382 /// NM_001164383 /// NM_001164384 /// NM_001164385 /// NM_014393 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204227_s_at NM_004614 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004614.1 /DEF=Homo sapiens thymidine kinase 2, mitochondrial (TK2), mRNA. /FEA=mRNA /GEN=TK2 /PROD=thymidine kinase 2, mitochondrial /DB_XREF=gi:10281329 /UG=Hs.274701 thymidine kinase 2, mitochondrial /FL=gb:NM_004614.1 gb:U77088.1" NM_004614 "thymidine kinase 2, mitochondrial" TK2 7084 NM_001172643 /// NM_001172644 /// NM_001172645 /// NM_001271934 /// NM_001271935 /// NM_001272050 /// NM_004614 /// NR_073520 /// NR_073521 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032042 // mitochondrial DNA metabolic process // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046092 // deoxycytidine metabolic process // inferred from electronic annotation /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 204228_at NM_006347 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006347.1 /DEF=Homo sapiens cyclophilin (USA-CYP), mRNA. /FEA=mRNA /GEN=USA-CYP /PROD=cyclophilin /DB_XREF=gi:5454153 /UG=Hs.9880 peptidyl prolyl isomerase H (cyclophilin H) /FL=gb:BC003412.1 gb:AF016371.1 gb:AF036331.1 gb:NM_006347.1" NM_006347 peptidylprolyl isomerase H (cyclophilin H) PPIH 10465 NM_006347 /// XM_005270362 /// XM_005270364 /// XM_005270366 /// XM_006710293 /// XR_426585 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0000413 // protein peptidyl-prolyl isomerization // inferred from direct assay /// 0000413 // protein peptidyl-prolyl isomerization // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype" 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosomal complex // inferred by curator /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from direct assay /// 0046540 // U4/U6 x U5 tri-snRNP complex // inferred from direct assay /// 0071001 // U4/U6 snRNP // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016018 // cyclosporin A binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0043021 // ribonucleoprotein complex binding // inferred from direct assay 204229_at H40895 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:H40895 /FEA=EST /DB_XREF=gi:916947 /DB_XREF=est:yn93f01.s1 /CLONE=IMAGE:175993 /UG=Hs.6535 brain-specific Na-dependent inorganic phosphate cotransporter /FL=gb:AB032436.1 gb:NM_020309.1 H40895 "solute carrier family 17 (vesicular glutamate transporter), member 7" SLC17A7 57030 NM_020309 "0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0042137 // sequestering of neurotransmitter // inferred from electronic annotation /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation" 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement 0005313 // L-glutamate transmembrane transporter activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015319 // sodium:inorganic phosphate symporter activity // inferred from direct assay /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from electronic annotation 204230_s_at NM_020309 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_020309.1 /DEF=Homo sapiens brain-specific Na-dependent inorganic phosphate cotransporter (BNPI), mRNA. /FEA=mRNA /GEN=BNPI /PROD=brain-specific Na-dependent inorganic phosphatecotransporter /DB_XREF=gi:9945321 /UG=Hs.6535 brain-specific Na-dependent inorganic phosphate cotransporter /FL=gb:AB032436.1 gb:NM_020309.1" NM_020309 "solute carrier family 17 (vesicular glutamate transporter), member 7" SLC17A7 57030 NM_020309 "0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // traceable author statement /// 0006836 // neurotransmitter transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007616 // long-term memory // inferred from electronic annotation /// 0014047 // glutamate secretion // traceable author statement /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0042137 // sequestering of neurotransmitter // inferred from electronic annotation /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation" 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0048786 // presynaptic active zone // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement 0005313 // L-glutamate transmembrane transporter activity // traceable author statement /// 0005315 // inorganic phosphate transmembrane transporter activity // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015319 // sodium:inorganic phosphate symporter activity // inferred from direct assay /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from electronic annotation 204231_s_at NM_001441 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001441.1 /DEF=Homo sapiens fatty acid amide hydrolase (FAAH), mRNA. /FEA=mRNA /GEN=FAAH /PROD=fatty acid amide hydrolase /DB_XREF=gi:4557574 /UG=Hs.326190 fatty acid amide hydrolase /FL=gb:U82535.1 gb:NM_001441.1" NM_001441 fatty acid amide hydrolase FAAH 2166 NM_001441 0008152 // metabolic process // inferred from electronic annotation /// 0009062 // fatty acid catabolic process // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from sequence or structural similarity "0016787 // hydrolase activity // inferred from electronic annotation /// 0016811 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0017064 // fatty acid amide hydrolase activity // inferred from direct assay /// 0047372 // acylglycerol lipase activity // inferred from electronic annotation" 204232_at NM_004106 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004106.1 /DEF=Homo sapiens Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide (FCER1G), mRNA. /FEA=mRNA /GEN=FCER1G /PROD=Fc fragment of IgE, high affinity I, receptorfor, gamma polypeptide precursor /DB_XREF=gi:4758343 /UG=Hs.743 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide /FL=gb:M33195.1 gb:NM_004106.1" NM_004106 "Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide" FCER1G 2207 NM_004106 "0001798 // positive regulation of type IIa hypersensitivity // inferred from electronic annotation /// 0001805 // positive regulation of type III hypersensitivity // inferred from electronic annotation /// 0001812 // positive regulation of type I hypersensitivity // inferred from electronic annotation /// 0002283 // neutrophil activation involved in immune response // inferred from electronic annotation /// 0002431 // Fc receptor mediated stimulatory signaling pathway // inferred from electronic annotation /// 0002554 // serotonin secretion by platelet // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0010543 // regulation of platelet activation // inferred from electronic annotation /// 0016064 // immunoglobulin mediated immune response // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032765 // positive regulation of mast cell cytokine production // inferred from electronic annotation /// 0033026 // negative regulation of mast cell apoptotic process // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0043306 // positive regulation of mast cell degranulation // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045576 // mast cell activation // inferred from electronic annotation /// 0050766 // positive regulation of phagocytosis // inferred from electronic annotation /// 0050776 // regulation of immune response // inferred from electronic annotation /// 0050778 // positive regulation of immune response // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement" 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032998 // Fc-epsilon receptor I complex // inferred from electronic annotation 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019767 // IgE receptor activity // inferred from electronic annotation /// 0019863 // IgE binding // inferred from electronic annotation /// 0019864 // IgG binding // inferred from electronic annotation 204233_s_at AI991328 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI991328 /FEA=EST /DB_XREF=gi:5838233 /DB_XREF=est:wu42f05.x1 /CLONE=IMAGE:2522721 /UG=Hs.77221 choline kinase /FL=gb:NM_001277.1 AI991328 choline kinase alpha CHKA 1119 NM_001277 /// NM_212469 /// XR_428904 /// XR_428905 /// XR_428906 /// XR_428907 0006629 // lipid metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from direct assay /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006657 // CDP-choline pathway // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019695 // choline metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004103 // choline kinase activity // inferred from direct assay /// 0004104 // cholinesterase activity // inferred from electronic annotation /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0033265 // choline binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation" 204234_s_at AI476267 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI476267 /FEA=EST /DB_XREF=gi:4329312 /DB_XREF=est:ti72g01.x1 /CLONE=IMAGE:2137584 /UG=Hs.104382 zinc finger protein 195 /FL=gb:AF003540.1 gb:NM_007152.1 AI476267 zinc finger protein 195 ZNF195 7748 NM_001130519 /// NM_001130520 /// NM_001242841 /// NM_001242842 /// NM_001242843 /// NM_001256823 /// NM_001256824 /// NM_001256825 /// NM_007152 /// NR_040083 /// NR_046381 /// NR_046382 /// XM_006718306 /// XM_006718307 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204235_s_at AF200715 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF200715.1 /DEF=Homo sapiens PTB domain adaptor protein CED-6 mRNA, complete cds. /FEA=mRNA /PROD=PTB domain adaptor protein CED-6 /DB_XREF=gi:6409467 /UG=Hs.107056 CED-6 protein /FL=gb:AF200715.1 gb:AF191771.1 gb:NM_016315.1" AF200715 "GULP, engulfment adaptor PTB domain containing 1" GULP1 51454 NM_001252668 /// NM_001252669 /// NM_016315 /// NR_045562 /// NR_045563 /// XM_006712580 /// XM_006712581 /// XM_006712582 /// XM_006712583 /// XM_006712584 /// XM_006712585 /// XM_006712586 /// XM_006712587 /// XM_006712588 /// XM_006712589 /// XM_006712590 /// XM_006712591 "0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement" 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204236_at NM_002017 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002017.2 /DEF=Homo sapiens Friend leukemia virus integration 1 (FLI1), mRNA. /FEA=mRNA /GEN=FLI1 /PROD=Friend leukemia virus integration 1 /DB_XREF=gi:7110592 /UG=Hs.108043 Friend leukemia virus integration 1 /FL=gb:BC001670.1 gb:M98833.3 gb:NM_002017.2" NM_002017 "Fli-1 proto-oncogene, ETS transcription factor" FLI1 2313 NM_001167681 /// NM_001271010 /// NM_001271012 /// NM_002017 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007599 // hemostasis // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement /// 0030154 // cell differentiation // not recorded" 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204237_at NM_016315 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016315.1 /DEF=Homo sapiens CED-6 protein (CED-6), mRNA. /FEA=mRNA /GEN=CED-6 /PROD=CED-6 protein /DB_XREF=gi:7705317 /UG=Hs.107056 CED-6 protein /FL=gb:AF200715.1 gb:AF191771.1 gb:NM_016315.1" NM_016315 "GULP, engulfment adaptor PTB domain containing 1" GULP1 51454 NM_001252668 /// NM_001252669 /// NM_016315 /// NR_045562 /// NR_045563 /// XM_006712580 /// XM_006712581 /// XM_006712582 /// XM_006712583 /// XM_006712584 /// XM_006712585 /// XM_006712586 /// XM_006712587 /// XM_006712588 /// XM_006712589 /// XM_006712590 /// XM_006712591 "0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement" 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 204238_s_at NM_006443 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006443.1 /DEF=Homo sapiens putative c-Myc-responsive (RCL), mRNA. /FEA=mRNA /GEN=RCL /PROD=putative c-Myc-responsive /DB_XREF=gi:5454001 /UG=Hs.109752 putative c-Myc-responsive /FL=gb:AF040105.1 gb:NM_006443.1" NM_006443 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 DNPH1 10591 NM_006443 /// NM_199184 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009159 // deoxyribonucleoside monophosphate catabolic process // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0016799 // hydrolase activity, hydrolyzing N-glycosyl compounds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0050144 // nucleoside deoxyribosyltransferase activity // inferred from electronic annotation /// 0070694 // deoxyribonucleoside 5'-monophosphate N-glycosidase activity // inferred from sequence or structural similarity" 204239_s_at NM_005386 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005386.1 /DEF=Homo sapiens neuronatin (NNAT), mRNA. /FEA=mRNA /GEN=NNAT /PROD=neuronatin /DB_XREF=gi:4885520 /UG=Hs.117546 neuronatin /FL=gb:U25033.1 gb:BC001768.1 gb:AB002392.1 gb:NM_005386.1" NM_005386 neuronatin NNAT 4826 NM_005386 /// NM_181689 0006810 // transport // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009249 // protein lipoylation // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 204240_s_at NM_006444 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006444.1 /DEF=Homo sapiens structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E (CAP-E), mRNA. /FEA=mRNA /GEN=CAP-E /PROD=structural maintenance of chromosomes (SMC)family member, chromosome-associated protein E /DB_XREF=gi:5453590 /UG=Hs.119023 SMC2 (structural maintenance of chromosomes 2, yeast)-like 1 /FL=gb:AF092563.1 gb:NM_006444.1" NM_006444 structural maintenance of chromosomes 2 SMC2 10592 NM_001042550 /// NM_001042551 /// NM_001265602 /// NM_006444 /// XM_006716933 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 204241_at BF055171 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BF055171 /FEA=EST /DB_XREF=gi:10809067 /DB_XREF=est:7j75g12.x1 /CLONE=IMAGE:3392326 /UG=Hs.12773 acyl-Coenzyme A oxidase 3, pristanoyl /FL=gb:NM_003501.1" BF055171 "acyl-CoA oxidase 3, pristanoyl" ACOX3 8310 NM_001101667 /// NM_003501 /// XM_005248011 /// XM_005248012 /// XM_005248013 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay "0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016402 // pristanoyl-CoA oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 204242_s_at NM_003501 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003501.1 /DEF=Homo sapiens acyl-Coenzyme A oxidase 3, pristanoyl (ACOX3), mRNA. /FEA=mRNA /GEN=ACOX3 /PROD=acyl-Coenzyme A oxidase 3, pristanoyl /DB_XREF=gi:4501870 /UG=Hs.12773 acyl-Coenzyme A oxidase 3, pristanoyl /FL=gb:NM_003501.1" NM_003501 "acyl-CoA oxidase 3, pristanoyl" ACOX3 8310 NM_001101667 /// NM_003501 /// XM_005248011 /// XM_005248012 /// XM_005248013 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // inferred from electronic annotation /// 0033540 // fatty acid beta-oxidation using acyl-CoA oxidase // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005782 // peroxisomal matrix // traceable author statement /// 0016020 // membrane // inferred from direct assay "0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0003997 // acyl-CoA oxidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0016402 // pristanoyl-CoA oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation" 204243_at NM_012421 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_012421.1 /DEF=Homo sapiens rearranged L-myc fusion sequence (RLF), mRNA. /FEA=mRNA /GEN=RLF /PROD=rearranged L-myc fusion sequence /DB_XREF=gi:6912631 /UG=Hs.13321 rearranged L-myc fusion sequence /FL=gb:U22377.1 gb:NM_012421.1" NM_012421 rearranged L-myc fusion RLF 6018 NM_012421 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0009294 // DNA mediated transformation // non-traceable author statement /// 0015074 // DNA integration // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051276 // chromosome organization // inferred from direct assay /// 0051276 // chromosome organization // non-traceable author statement" 0005634 // nucleus // inferred by curator 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204244_s_at NM_006716 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006716.1 /DEF=Homo sapiens activator of S phase kinase (ASK), mRNA. /FEA=mRNA /GEN=ASK /PROD=activator of S phase kinase /DB_XREF=gi:5729733 /UG=Hs.152759 activator of S phase kinase /FL=gb:AB028069.1 gb:AF160249.1 gb:AF160876.1 gb:NM_006716.1" NM_006716 DBF4 zinc finger DBF4 10926 NM_006716 /// XM_005250120 /// XM_005250121 /// XM_005250122 /// XM_006715843 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204245_s_at AW242755 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AW242755 /FEA=EST /DB_XREF=gi:6576602 /DB_XREF=est:xm90f12.x1 /CLONE=IMAGE:2691503 /UG=Hs.155150 ribonuclease P (14kD) /FL=gb:AF001175.1 gb:NM_007042.1 AW242755 ribonuclease P/MRP 14kDa subunit RPP14 11102 NM_001098783 /// NM_007042 /// NR_049755 /// NR_049756 /// NR_049757 /// NR_049758 "0008033 // tRNA processing // inferred from electronic annotation /// 0090501 // RNA phosphodiester bond hydrolysis // inferred from electronic annotation /// 0090502 // RNA phosphodiester bond hydrolysis, endonucleolytic // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0004526 // ribonuclease P activity // inferred from electronic annotation /// 0004540 // ribonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204246_s_at NM_007234 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007234.2 /DEF=Homo sapiens dynactin 3 (p22) (DCTN3), transcript variant 1, mRNA. /FEA=mRNA /GEN=DCTN3 /PROD=dynactin 3, isoform 1 /DB_XREF=gi:13259516 /UG=Hs.15961 dynactin 3 (p22) /FL=gb:NM_007234.2 gb:AF082513.1" NM_007234 dynactin 3 (p22) DCTN3 11258 NM_001281425 /// NM_001281426 /// NM_001281427 /// NM_007234 /// NM_024348 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from direct assay /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0051301 // cell division // inferred from electronic annotation "0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from physical interaction /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay" 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204247_s_at NM_004935 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004935.1 /DEF=Homo sapiens cyclin-dependent kinase 5 (CDK5), mRNA. /FEA=mRNA /GEN=CDK5 /PROD=cyclin-dependent kinase 5 /DB_XREF=gi:4826674 /UG=Hs.166071 cyclin-dependent kinase 5 /FL=gb:BC005115.1 gb:NM_004935.1" NM_004935 cyclin-dependent kinase 5 CDK5 1020 NM_001164410 /// NM_004935 "0001764 // neuron migration // traceable author statement /// 0001963 // synaptic transmission, dopaminergic // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008306 // associative learning // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0014044 // Schwann cell development // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // traceable author statement /// 0016310 // phosphorylation // inferred from direct assay /// 0016477 // cell migration // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from electronic annotation /// 0021697 // cerebellar cortex formation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021819 // layer formation in cerebral cortex // inferred from electronic annotation /// 0021954 // central nervous system neuron development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0022038 // corpus callosum development // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030182 // neuron differentiation // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030517 // negative regulation of axon extension // inferred from electronic annotation /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from sequence or structural similarity /// 0031397 // negative regulation of protein ubiquitination // inferred from electronic annotation /// 0031914 // negative regulation of synaptic plasticity // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0032801 // receptor catabolic process // inferred from electronic annotation /// 0033136 // serine phosphorylation of STAT3 protein // inferred from electronic annotation /// 0035249 // synaptic transmission, glutamatergic // inferred from electronic annotation /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043113 // receptor clustering // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046826 // negative regulation of protein export from nucleus // inferred from electronic annotation /// 0048148 // behavioral response to cocaine // inferred from electronic annotation /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // traceable author statement /// 0048488 // synaptic vesicle endocytosis // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048675 // axon extension // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from direct assay /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0060078 // regulation of postsynaptic membrane potential // inferred from electronic annotation /// 0060079 // regulation of excitatory postsynaptic membrane potential // inferred from electronic annotation /// 0061001 // regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0070509 // calcium ion import // inferred from electronic annotation /// 0071156 // regulation of cell cycle arrest // traceable author statement /// 0090314 // positive regulation of protein targeting to membrane // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 2000251 // positive regulation of actin cytoskeleton reorganization // traceable author statement /// 2000273 // positive regulation of receptor activity // inferred from electronic annotation /// 2000273 // positive regulation of receptor activity // inferred from sequence or structural similarity" 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016533 // cyclin-dependent protein kinase 5 holoenzyme complex // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043204 // perikaryon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0002039 // p53 binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005176 // ErbB-2 class receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030549 // acetylcholine receptor activator activity // inferred from sequence or structural similarity /// 0043125 // ErbB-3 class receptor binding // inferred from sequence or structural similarity /// 0046875 // ephrin receptor binding // inferred from electronic annotation /// 0050321 // tau-protein kinase activity // inferred from sequence or structural similarity" 204248_at NM_002067 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002067.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha 11 (Gq class) (GNA11), mRNA. /FEA=mRNA /GEN=GNA11 /PROD=guanine nucleotide binding protein (G protein),alpha 11 (Gq class) /DB_XREF=gi:4504036 /UG=Hs.1686 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) /FL=gb:M69013.1 gb:AF011497.1 gb:NM_002067.1" NM_002067 "guanine nucleotide binding protein (G protein), alpha 11 (Gq class)" GNA11 2767 NM_002067 0001501 // skeletal system development // inferred from electronic annotation /// 0001508 // action potential // not recorded /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045634 // regulation of melanocyte differentiation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0060158 // phospholipase C-activating dopamine receptor signaling pathway // not recorded 0005737 // cytoplasm // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001664 // G-protein coupled receptor binding // not recorded /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // not recorded /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031826 // type 2A serotonin receptor binding // /// 0046872 // metal ion binding // inferred from electronic annotation 204249_s_at NM_005574 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005574.2 /DEF=Homo sapiens LIM domain only 2 (rhombotin-like 1) (LMO2), mRNA. /FEA=mRNA /GEN=LMO2 /PROD=LIM domain only 2 /DB_XREF=gi:6633806 /UG=Hs.184585 LIM domain only 2 (rhombotin-like 1) /FL=gb:NM_005574.2" NM_005574 LIM domain only 2 (rhombotin-like 1) LMO2 4005 NM_001142315 /// NM_001142316 /// NM_005574 /// XM_005252920 /// XM_005252921 /// XM_006718229 0007275 // multicellular organismal development // traceable author statement /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0045647 // negative regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from physical interaction /// 0070888 // E-box binding // inferred from direct assay 204250_s_at AI655714 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI655714 /FEA=EST /DB_XREF=gi:4739693 /DB_XREF=est:tt14f03.x1 /CLONE=IMAGE:2240765 /UG=Hs.18624 KIAA1052 protein /FL=gb:AB028975.1 gb:NM_014956.1 AI655714 centrosomal protein 164kDa CEP164 22897 NM_001271933 /// NM_014956 /// XM_005271452 /// XM_005271453 /// XM_005271454 /// XM_005271455 /// XM_005271456 /// XM_005271457 /// XM_005271458 /// XM_005271459 /// XM_005271460 /// XM_006718788 /// XM_006718789 /// XM_006718790 /// XM_006718791 /// XM_006718792 /// XM_006718793 /// XM_006718794 /// XR_428971 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0097539 // ciliary transition fiber // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204251_s_at NM_014956 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014956.1 /DEF=Homo sapiens KIAA1052 protein (KIAA1052), mRNA. /FEA=mRNA /GEN=KIAA1052 /PROD=KIAA1052 protein /DB_XREF=gi:7662463 /UG=Hs.18624 KIAA1052 protein /FL=gb:AB028975.1 gb:NM_014956.1" NM_014956 centrosomal protein 164kDa CEP164 22897 NM_001271933 /// NM_014956 /// XM_005271452 /// XM_005271453 /// XM_005271454 /// XM_005271455 /// XM_005271456 /// XM_005271457 /// XM_005271458 /// XM_005271459 /// XM_005271460 /// XM_006718788 /// XM_006718789 /// XM_006718790 /// XM_006718791 /// XM_006718792 /// XM_006718793 /// XM_006718794 /// XR_428971 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0030030 // cell projection organization // inferred from electronic annotation /// 0042384 // cilium assembly // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0097539 // ciliary transition fiber // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204252_at M68520 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M68520.1 /DEF=Human cdc2-related protein kinase mRNA, complete cds. /FEA=mRNA /PROD=cdc2-related protein kinase /DB_XREF=gi:180177 /UG=Hs.19192 cyclin-dependent kinase 2 /FL=gb:BC003065.1 gb:M68520.1 gb:NM_001798.1" M68520 cyclin-dependent kinase 2 CDK2 1017 NM_001290230 /// NM_001798 /// NM_052827 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000085 // mitotic G2 phase // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016572 // histone phosphorylation // inferred from direct assay /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0031571 // mitotic G1 DNA damage checkpoint // traceable author statement /// 0032298 // positive regulation of DNA-dependent DNA replication initiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051298 // centrosome duplication // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060968 // regulation of gene silencing // inferred from direct assay /// 0071732 // cellular response to nitric oxide // traceable author statement" "0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000805 // X chromosome // inferred from electronic annotation /// 0000806 // Y chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005813 // centrosome // traceable author statement /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay" "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030332 // cyclin binding // inferred from direct assay /// 0035173 // histone kinase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 204253_s_at AA454701 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA454701 /FEA=EST /DB_XREF=gi:2177477 /DB_XREF=est:zx76e01.s1 /CLONE=IMAGE:809688 /UG=Hs.2062 vitamin D (1,25- dihydroxyvitamin D3) receptor /FL=gb:AF026260.1 gb:J03258.1 gb:NM_000376.1" AA454701 "vitamin D (1,25- dihydroxyvitamin D3) receptor" VDR 7421 NM_000376 /// NM_001017535 /// NM_001017536 /// XM_006719587 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0038183 // bile acid signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060558 // regulation of calcidiol 1-monooxygenase activity // inferred from sequence or structural similarity /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0070561 // vitamin D receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008434 // calcitriol receptor activity // inferred from direct assay /// 0038186 // lithocholic acid receptor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 1902098 // calcitriol binding // inferred from direct assay /// 1902121 // lithocholic acid binding // inferred from direct assay 204254_s_at NM_000376 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000376.1 /DEF=Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor (VDR), mRNA. /FEA=mRNA /GEN=VDR /PROD=vitamin D (1,25- dihydroxyvitamin D3) receptor /DB_XREF=gi:4507882 /UG=Hs.2062 vitamin D (1,25- dihydroxyvitamin D3) receptor /FL=gb:AF026260.1 gb:J03258.1 gb:NM_000376.1" NM_000376 "vitamin D (1,25- dihydroxyvitamin D3) receptor" VDR 7421 NM_000376 /// NM_001017535 /// NM_001017536 /// XM_006719587 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0038183 // bile acid signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060558 // regulation of calcidiol 1-monooxygenase activity // inferred from sequence or structural similarity /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0070561 // vitamin D receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008434 // calcitriol receptor activity // inferred from direct assay /// 0038186 // lithocholic acid receptor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 1902098 // calcitriol binding // inferred from direct assay /// 1902121 // lithocholic acid binding // inferred from direct assay 204255_s_at AA772285 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA772285 /FEA=EST /DB_XREF=gi:2824068 /DB_XREF=est:ai42d11.s1 /CLONE=1359669 /UG=Hs.2062 vitamin D (1,25- dihydroxyvitamin D3) receptor /FL=gb:AF026260.1 gb:J03258.1 gb:NM_000376.1" AA772285 "vitamin D (1,25- dihydroxyvitamin D3) receptor" VDR 7421 NM_000376 /// NM_001017535 /// NM_001017536 /// XM_006719587 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from mutant phenotype /// 0001501 // skeletal system development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010839 // negative regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0010980 // positive regulation of vitamin D 24-hydroxylase activity // inferred from direct assay /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0038183 // bile acid signaling pathway // inferred from direct assay /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046697 // decidualization // inferred from expression pattern /// 0050892 // intestinal absorption // inferred from electronic annotation /// 0060058 // positive regulation of apoptotic process involved in mammary gland involution // inferred from electronic annotation /// 0060558 // regulation of calcidiol 1-monooxygenase activity // inferred from sequence or structural similarity /// 0060745 // mammary gland branching involved in pregnancy // inferred from electronic annotation /// 0070561 // vitamin D receptor signaling pathway // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004879 // ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008434 // calcitriol receptor activity // inferred from direct assay /// 0038186 // lithocholic acid receptor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046965 // retinoid X receptor binding // inferred from physical interaction /// 0070644 // vitamin D response element binding // inferred from direct assay /// 1902098 // calcitriol binding // inferred from direct assay /// 1902121 // lithocholic acid binding // inferred from direct assay 204256_at NM_024090 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024090.1 /DEF=Homo sapiens hypothetical protein MGC5487 (MGC5487), mRNA. /FEA=mRNA /GEN=MGC5487 /PROD=hypothetical protein MGC5487 /DB_XREF=gi:13129087 /UG=Hs.211556 hypothetical protein MGC5487 /FL=gb:NM_024090.1" NM_024090 ELOVL fatty acid elongase 6 ELOVL6 79071 NM_001130721 /// NM_024090 "0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0019367 // fatty acid elongation, saturated fatty acid // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0030497 // fatty acid elongation // inferred from electronic annotation /// 0035338 // long-chain fatty-acyl-CoA biosynthetic process // traceable author statement /// 0042759 // long-chain fatty acid biosynthetic process // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement" 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from electronic annotation "0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation" 204257_at NM_021727 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021727.1 /DEF=Homo sapiens fatty acid desaturase 3 (FADS3), mRNA. /FEA=mRNA /GEN=FADS3 /PROD=fatty acid desaturase 3 /DB_XREF=gi:13375615 /UG=Hs.21765 fatty acid desaturase 3 /FL=gb:AF084560.1 gb:NM_021727.1 gb:BC004901.1 gb:AF134404.1" NM_021727 fatty acid desaturase 3 FADS3 3995 NM_021727 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006636 // unsaturated fatty acid biosynthetic process // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation "0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation" 204258_at NM_001270 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001270.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 1 (CHD1), mRNA. /FEA=mRNA /GEN=CHD1 /PROD=chromodomain helicase DNA binding protein 1 /DB_XREF=gi:4557446 /UG=Hs.22670 chromodomain helicase DNA binding protein 1 /FL=gb:AF006513.1 gb:NM_001270.1" NM_001270 chromodomain helicase DNA binding protein 1 CHD1 1105 NM_001270 /// XM_005271866 /// XM_005271867 /// XR_427702 "0006338 // chromatin remodeling // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // traceable author statement" 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035064 // methylated histone binding // inferred from direct assay 204259_at NM_002423 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002423.2 /DEF=Homo sapiens matrix metalloproteinase 7 (matrilysin, uterine) (MMP7), mRNA. /FEA=mRNA /GEN=MMP7 /PROD=matrix metalloproteinase 7 preproprotein /DB_XREF=gi:13027804 /UG=Hs.2256 matrix metalloproteinase 7 (matrilysin, uterine) /FL=gb:NM_002423.2 gb:BC003635.1" NM_002423 "matrix metallopeptidase 7 (matrilysin, uterine)" MMP7 4316 NM_002423 0002779 // antibacterial peptide secretion // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204260_at NM_001819 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001819.1 /DEF=Homo sapiens chromogranin B (secretogranin 1) (CHGB), mRNA. /FEA=mRNA /GEN=CHGB /PROD=chromogranin B precursor /DB_XREF=gi:4502806 /UG=Hs.2281 chromogranin B (secretogranin 1) /FL=gb:BC000375.1 gb:NM_001819.1" NM_001819 chromogranin B (secretogranin 1) CHGB 1114 NM_001819 0005576 // extracellular region // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204261_s_at AA716657 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA716657 /FEA=EST /DB_XREF=gi:2728931 /DB_XREF=est:zg70h11.s1 /CLONE=IMAGE:398757 /UG=Hs.25363 presenilin 2 (Alzheimer disease 4) /FL=gb:NM_000447.1 gb:NM_012486.1 gb:L44577.1 gb:L43964.1 AA716657 presenilin 2 PSEN2 5664 NM_000447 /// NM_012486 /// XM_005273199 0001666 // response to hypoxia // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // inferred from direct assay /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030426 // growth cone // not recorded /// 0031594 // neuromuscular junction // not recorded /// 0035253 // ciliary rootlet // not recorded /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded 0004175 // endopeptidase activity // not recorded /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204262_s_at NM_000447 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000447.1 /DEF=Homo sapiens presenilin 2 (Alzheimer disease 4) (PSEN2), transcript variant 1, mRNA. /FEA=mRNA /GEN=PSEN2 /PROD=presenilin 2 isoform 1 /DB_XREF=gi:4506164 /UG=Hs.25363 presenilin 2 (Alzheimer disease 4) /FL=gb:NM_000447.1 gb:NM_012486.1 gb:L44577.1 gb:L43964.1" NM_000447 presenilin 2 PSEN2 5664 NM_000447 /// NM_012486 /// XM_005273199 0001666 // response to hypoxia // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001756 // somitogenesis // inferred from electronic annotation /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002286 // T cell activation involved in immune response // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from direct assay /// 0006816 // calcium ion transport // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007176 // regulation of epidermal growth factor-activated receptor activity // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007220 // Notch receptor processing // not recorded /// 0007220 // Notch receptor processing // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016485 // protein processing // inferred from direct assay /// 0021904 // dorsal/ventral neural tube patterning // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031293 // membrane protein intracellular domain proteolysis // traceable author statement /// 0031333 // negative regulation of protein complex assembly // inferred from electronic annotation /// 0032091 // negative regulation of protein binding // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0040011 // locomotion // inferred from electronic annotation /// 0042640 // anagen // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // not recorded /// 0042987 // amyloid precursor protein catabolic process // traceable author statement /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048854 // brain morphogenesis // inferred from electronic annotation /// 0050435 // beta-amyloid metabolic process // not recorded /// 0050820 // positive regulation of coagulation // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0005637 // nuclear inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // not recorded /// 0005765 // lysosomal membrane // not recorded /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0030018 // Z disc // not recorded /// 0030424 // axon // not recorded /// 0030426 // growth cone // not recorded /// 0031594 // neuromuscular junction // not recorded /// 0035253 // ciliary rootlet // not recorded /// 0043025 // neuronal cell body // not recorded /// 0043198 // dendritic shaft // not recorded /// 0043234 // protein complex // inferred from direct assay /// 0045121 // membrane raft // not recorded /// 0048471 // perinuclear region of cytoplasm // not recorded 0004175 // endopeptidase activity // not recorded /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204263_s_at M58581 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M58581.1 /DEF=Human carnitine palmitoyltransferase (CPT1) mRNA, complete cds. /FEA=mRNA /GEN=CPT1 /PROD=carnitine palmitoyltransferase /DB_XREF=gi:180988 /UG=Hs.274336 carnitine palmitoyltransferase II /FL=gb:U09648.1 gb:BC002445.1 gb:BC005172.1 gb:M58581.1 gb:NM_000098.1" M58581 carnitine palmitoyltransferase 2 CPT2 1376 NM_000098 /// XM_005270484 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0004095 // carnitine O-palmitoyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation" 204264_at NM_000098 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000098.1 /DEF=Homo sapiens carnitine palmitoyltransferase II (CPT2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=CPT2 /PROD=carnitine palmitoyltransferase II /DB_XREF=gi:4503022 /UG=Hs.274336 carnitine palmitoyltransferase II /FL=gb:U09648.1 gb:BC002445.1 gb:BC005172.1 gb:M58581.1 gb:NM_000098.1" NM_000098 carnitine palmitoyltransferase 2 CPT2 1376 NM_000098 /// XM_005270484 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // non-traceable author statement /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation "0004095 // carnitine O-palmitoyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation" 204265_s_at NM_022107 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022107.1 /DEF=Homo sapiens G18.2 protein (G18.2), mRNA. /FEA=mRNA /GEN=G18.2 /PROD=G18.2 protein /DB_XREF=gi:11545816 /UG=Hs.288316 chromosome 6 open reading frame 9 /FL=gb:NM_022107.1 gb:AF155657.1" NM_022107 G-protein signaling modulator 3 GPSM3 63940 NM_001276501 /// NM_022107 0006955 // immune response // non-traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0005092 // GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0030695 // GTPase regulator activity // inferred from electronic annotation 204266_s_at NM_001277 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001277.1 /DEF=Homo sapiens choline kinase (CHK), mRNA. /FEA=mRNA /GEN=CHK /PROD=choline kinase /DB_XREF=gi:4557454 /UG=Hs.77221 choline kinase /FL=gb:NM_001277.1" NM_001277 choline kinase alpha CHKA 1119 NM_001277 /// NM_212469 /// XR_428904 /// XR_428905 /// XR_428906 /// XR_428907 0006629 // lipid metabolic process // traceable author statement /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from direct assay /// 0006646 // phosphatidylethanolamine biosynthetic process // inferred from electronic annotation /// 0006646 // phosphatidylethanolamine biosynthetic process // traceable author statement /// 0006656 // phosphatidylcholine biosynthetic process // inferred from direct assay /// 0006656 // phosphatidylcholine biosynthetic process // traceable author statement /// 0006657 // CDP-choline pathway // inferred from direct assay /// 0006657 // CDP-choline pathway // inferred from electronic annotation /// 0006657 // CDP-choline pathway // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019695 // choline metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004103 // choline kinase activity // inferred from direct assay /// 0004104 // cholinesterase activity // inferred from electronic annotation /// 0004305 // ethanolamine kinase activity // inferred from direct assay /// 0004871 // signal transducer activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008144 // drug binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0033265 // choline binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation" 204267_x_at NM_004203 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004203.1 /DEF=Homo sapiens membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1), mRNA. /FEA=mRNA /GEN=PKMYT1 /PROD=membrane-associated tyrosine- andthreonine-specific cdc2-inhibitory kinase /DB_XREF=gi:4758927 /UG=Hs.77783 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase /FL=gb:U56816.1 gb:AF014118.1 gb:NM_004203.1" NM_004203 "protein kinase, membrane associated tyrosine/threonine 1" PKMYT1 9088 NM_001258450 /// NM_001258451 /// NM_004203 /// NM_182687 /// XM_005255675 /// XM_006720976 0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007088 // regulation of mitosis // traceable author statement /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0051726 // regulation of cell cycle // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204268_at NM_005978 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005978.2 /DEF=Homo sapiens S100 calcium-binding protein A2 (S100A2), mRNA. /FEA=mRNA /GEN=S100A2 /PROD=S100 calcium-binding protein A2 /DB_XREF=gi:9845513 /UG=Hs.38991 S100 calcium-binding protein A2 /FL=gb:BC002829.1 gb:NM_005978.2" NM_005978 S100 calcium binding protein A2 S100A2 6273 NM_005978 0043542 // endothelial cell migration // inferred from mutant phenotype 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204269_at NM_006875 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006875.1 /DEF=Homo sapiens pim-2 oncogene (PIM2), mRNA. /FEA=mRNA /GEN=PIM2 /PROD=pim-2 oncogene /DB_XREF=gi:5803124 /UG=Hs.80205 pim-2 oncogene /FL=gb:U77735.1 gb:NM_006875.1" NM_006875 "Pim-2 proto-oncogene, serine/threonine kinase" PIM2 11040 NM_006875 "0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007140 // male meiosis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0010508 // positive regulation of autophagy // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity" "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation" 204270_at AI568728 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI568728 /FEA=EST /DB_XREF=gi:4532102 /DB_XREF=est:th15a06.x1 /CLONE=IMAGE:2118322 /UG=Hs.2969 v-ski avian sarcoma viral oncogene homolog /FL=gb:NM_003036.1 AI568728 SKI proto-oncogene SKI 6497 NM_003036 /// XM_005244775 /// XM_005244776 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001843 // neural tube closure // inferred from sequence or structural similarity /// 0002089 // lens morphogenesis in camera-type eye // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009948 // anterior/posterior axis specification // inferred from sequence or structural similarity /// 0010467 // gene expression // traceable author statement /// 0010626 // negative regulation of Schwann cell proliferation // inferred from genetic interaction /// 0014902 // myotube differentiation // inferred from direct assay /// 0021772 // olfactory bulb development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // non-traceable author statement /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from genetic interaction /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030514 // negative regulation of BMP signaling pathway // inferred from direct assay /// 0030514 // negative regulation of BMP signaling pathway // inferred from mutant phenotype /// 0031064 // negative regulation of histone deacetylation // inferred from electronic annotation /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from sequence or structural similarity /// 0042981 // regulation of apoptotic process // not recorded /// 0042981 // regulation of apoptotic process // inferred from sequence or structural similarity /// 0043010 // camera-type eye development // inferred from sequence or structural similarity /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0043585 // nose morphogenesis // inferred from sequence or structural similarity /// 0045668 // negative regulation of osteoblast differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0048870 // cell motility // non-traceable author statement /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060041 // retina development in camera-type eye // inferred from sequence or structural similarity /// 0060325 // face morphogenesis // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0070207 // protein homotrimerization // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0016604 // nuclear body // inferred from direct assay /// 0016605 // PML body // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from physical interaction /// 0046811 // histone deacetylase inhibitor activity // inferred from sequence or structural similarity /// 0070491 // repressing transcription factor binding // inferred from physical interaction 204271_s_at M74921 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M74921.1 /DEF=Human endothelin receptor mRNA, complete cds. /FEA=mRNA /GEN=ETs /PROD=endothelin receptor /DB_XREF=gi:182275 /UG=Hs.82002 endothelin receptor type B /FL=gb:M74921.1 gb:D90402.1 gb:NM_000115.1" M74921 endothelin receptor type B EDNRB 1910 NM_000115 /// NM_001122659 /// NM_001201397 /// NM_003991 /// NR_047024 /// XM_005266275 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014043 // negative regulation of neuron maturation // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014826 // vein smooth muscle contraction // inferred from mutant phenotype /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019934 // cGMP-mediated signaling // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0031620 // regulation of fever generation // inferred from electronic annotation /// 0032269 // negative regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035645 // enteric smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042311 // vasodilation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from mutant phenotype /// 0048265 // response to pain // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from direct assay /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // inferred from direct assay /// 0004962 // endothelin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 204272_at NM_006149 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006149.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 4 (galectin 4) (LGALS4), mRNA. /FEA=mRNA /GEN=LGALS4 /PROD=galectin 4 /DB_XREF=gi:6006017 /UG=Hs.5302 lectin, galactoside-binding, soluble, 4 (galectin 4) /FL=gb:BC003661.1 gb:BC005146.1 gb:AF014838.1 gb:AB006781.1 gb:U82953.1 gb:NM_006149.2" NM_006149 "lectin, galactoside-binding, soluble, 4" LGALS4 3960 NM_006149 0007155 // cell adhesion // traceable author statement 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation 204273_at NM_000115 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000115.1 /DEF=Homo sapiens endothelin receptor type B (EDNRB), transcript variant 1, mRNA. /FEA=mRNA /GEN=EDNRB /PROD=endothelin receptor type B, isoform 1 /DB_XREF=gi:4557546 /UG=Hs.82002 endothelin receptor type B /FL=gb:M74921.1 gb:D90402.1 gb:NM_000115.1" NM_000115 endothelin receptor type B EDNRB 1910 NM_000115 /// NM_001122659 /// NM_001201397 /// NM_003991 /// NR_047024 /// XM_005266275 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007497 // posterior midgut development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0014043 // negative regulation of neuron maturation // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014826 // vein smooth muscle contraction // inferred from mutant phenotype /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0019934 // cGMP-mediated signaling // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0031620 // regulation of fever generation // inferred from electronic annotation /// 0032269 // negative regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0035645 // enteric smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0035810 // positive regulation of urine volume // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042045 // epithelial fluid transport // inferred from electronic annotation /// 0042310 // vasoconstriction // inferred from mutant phenotype /// 0042311 // vasodilation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048246 // macrophage chemotaxis // inferred from mutant phenotype /// 0048265 // response to pain // inferred from electronic annotation /// 0048484 // enteric nervous system development // inferred from sequence or structural similarity /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051930 // regulation of sensory perception of pain // inferred from electronic annotation /// 0060406 // positive regulation of penile erection // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from direct assay /// 0086100 // endothelin receptor signaling pathway // inferred from electronic annotation /// 0086100 // endothelin receptor signaling pathway // inferred from mutant phenotype 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004962 // endothelin receptor activity // inferred from direct assay /// 0004962 // endothelin receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 204274_at AA812215 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AA812215 /FEA=EST /DB_XREF=gi:2881826 /DB_XREF=est:ob84g01.s1 /CLONE=IMAGE:1338096 /UG=Hs.9222 estrogen receptor binding site associated, antigen, 9 /FL=gb:BC005249.1 gb:AF006265.1 gb:AB007619.1 gb:NM_004215.1" AA812215 "estrogen receptor binding site associated, antigen, 9" EBAG9 9166 NM_001278938 /// NM_004215 /// NM_198120 0001558 // regulation of cell growth // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016505 // peptidase activator activity involved in apoptotic process // non-traceable author statement 204275_at AI796687 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI796687 /FEA=EST /DB_XREF=gi:5362150 /DB_XREF=est:wh59f02.x1 /CLONE=IMAGE:2385051 /UG=Hs.55836 small optic lobes (Drosophila) homolog /FL=gb:U85647.1 gb:NM_005632.1 AI796687 calpain 15 CAPN15 6650 NM_005632 /// XM_005255514 /// XM_005255516 /// XM_005255517 /// XM_005255518 /// XM_006720931 /// XM_006720932 /// XM_006720933 /// XM_006720934 /// XM_006720935 "0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0006508 // proteolysis // not recorded" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // not recorded /// 0008233 // peptidase activity // traceable author statement /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204276_at BE895437 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE895437 /FEA=EST /DB_XREF=gi:10358829 /DB_XREF=est:601437912F1 /CLONE=IMAGE:3922971 /UG=Hs.274701 thymidine kinase 2, mitochondrial /FL=gb:NM_004614.1 gb:U77088.1" BE895437 "thymidine kinase 2, mitochondrial" TK2 7084 NM_001172643 /// NM_001172644 /// NM_001172645 /// NM_001271934 /// NM_001271935 /// NM_001272050 /// NM_004614 /// NR_073520 /// NR_073521 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032042 // mitochondrial DNA metabolic process // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046092 // deoxycytidine metabolic process // inferred from electronic annotation /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 204277_s_at BE895437 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:BE895437 /FEA=EST /DB_XREF=gi:10358829 /DB_XREF=est:601437912F1 /CLONE=IMAGE:3922971 /UG=Hs.274701 thymidine kinase 2, mitochondrial /FL=gb:NM_004614.1 gb:U77088.1" BE895437 "thymidine kinase 2, mitochondrial" TK2 7084 NM_001172643 /// NM_001172644 /// NM_001172645 /// NM_001271934 /// NM_001271935 /// NM_001272050 /// NM_004614 /// NR_073520 /// NR_073521 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009262 // deoxyribonucleotide metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032042 // mitochondrial DNA metabolic process // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046092 // deoxycytidine metabolic process // inferred from electronic annotation /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement "0000166 // nucleotide binding // inferred from electronic annotation /// 0004137 // deoxycytidine kinase activity // inferred from electronic annotation /// 0004797 // thymidine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 204278_s_at NM_004215 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004215.1 /DEF=Homo sapiens estrogen receptor binding site associated, antigen, 9 (EBAG9), mRNA. /FEA=mRNA /GEN=EBAG9 /PROD=estrogen receptor binding site associated,antigen, 9 /DB_XREF=gi:4758229 /UG=Hs.9222 estrogen receptor binding site associated, antigen, 9 /FL=gb:BC005249.1 gb:AF006265.1 gb:AB007619.1 gb:NM_004215.1" NM_004215 "estrogen receptor binding site associated, antigen, 9" EBAG9 9166 NM_001278938 /// NM_004215 /// NM_198120 0001558 // regulation of cell growth // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0016505 // peptidase activator activity involved in apoptotic process // non-traceable author statement 204279_at NM_002800 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002800.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2) (PSMB9), mRNA. /FEA=mRNA /GEN=PSMB9 /PROD=proteasome (prosome, macropain) subunit, betatype, 9 (large multifunctional protease 2) /DB_XREF=gi:4506204 /UG=Hs.9280 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2) /FL=gb:U01025.1 gb:NM_002800.1" NM_002800 "proteasome (prosome, macropain) subunit, beta type, 9" PSMB9 5698 NM_002800 /// NM_148954 "0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000209 // protein polyubiquitination // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002479 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation" 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005839 // proteasome core complex // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 1990111 // spermatoproteasome complex // inferred from sequence or structural similarity 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 204280_at NM_006480 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006480.1 /DEF=Homo sapiens regulator of G-protein signalling 14 (RGS14), mRNA. /FEA=mRNA /GEN=RGS14 /PROD=regulator of G-protein signalling 14 /DB_XREF=gi:5454005 /UG=Hs.9347 regulator of G-protein signalling 14 /FL=gb:AF037195.1 gb:NM_006480.1" NM_006480 regulator of G-protein signaling 14 RGS14 10636 NM_006480 /// XM_005265794 /// XM_005265795 0006913 // nucleocytoplasmic transport // inferred from sequence or structural similarity /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0007049 // cell cycle // inferred from electronic annotation /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from sequence or structural similarity /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007612 // learning // inferred from sequence or structural similarity /// 0007616 // long-term memory // inferred from sequence or structural similarity /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0010070 // zygote asymmetric cell division // inferred from sequence or structural similarity /// 0031914 // negative regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0043620 // regulation of DNA-templated transcription in response to stress // inferred from sequence or structural similarity /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0050769 // positive regulation of neurogenesis // inferred from sequence or structural similarity /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051301 // cell division // inferred from mutant phenotype /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity 0000922 // spindle pole // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016604 // nuclear body // inferred from sequence or structural similarity /// 0016605 // PML body // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from sequence or structural similarity /// 0005092 // GDP-dissociation inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // not recorded /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008017 // microtubule binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // inferred from sequence or structural similarity /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0032794 // GTPase activating protein binding // inferred from electronic annotation 204281_at NM_003213 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003213.1 /DEF=Homo sapiens TEA domain family member 4 (TEAD4), mRNA. /FEA=mRNA /GEN=TEAD4 /PROD=TEA domain family member 4 /DB_XREF=gi:4507426 /UG=Hs.94865 TEA domain family member 4 /FL=gb:U63824.1 gb:NM_003213.1" NM_003213 TEA domain family member 4 TEAD4 7004 NM_003213 /// NM_201441 /// NM_201443 "0001501 // skeletal system development // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001708 // cell fate specification // inferred from electronic annotation /// 0001825 // blastocyst formation // inferred from electronic annotation /// 0001830 // trophectodermal cell fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007517 // muscle organ development // traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0035329 // hippo signaling // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204282_s_at NM_006567 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006567.1 /DEF=Homo sapiens phenylalanine-tRNA synthetase (FARS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FARS1 /PROD=phenylalanine-tRNA synthetase /DB_XREF=gi:5729819 /UG=Hs.57969 phenylalanine-tRNA synthetase /FL=gb:AF097441.1 gb:NM_006567.1" NM_006567 "phenylalanyl-tRNA synthetase 2, mitochondrial" FARS2 10667 NM_006567 /// XM_005248811 /// XM_005248812 /// XM_005248813 /// XM_005248814 /// XM_006714966 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 204283_at NM_006567 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006567.1 /DEF=Homo sapiens phenylalanine-tRNA synthetase (FARS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=FARS1 /PROD=phenylalanine-tRNA synthetase /DB_XREF=gi:5729819 /UG=Hs.57969 phenylalanine-tRNA synthetase /FL=gb:AF097441.1 gb:NM_006567.1" NM_006567 "phenylalanyl-tRNA synthetase 2, mitochondrial" FARS2 10667 NM_006567 /// XM_005248811 /// XM_005248812 /// XM_005248813 /// XM_005248814 /// XM_006714966 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006432 // phenylalanyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0000049 // tRNA binding // inferred from direct assay /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004826 // phenylalanine-tRNA ligase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 204284_at N26005 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:N26005 /FEA=EST /DB_XREF=gi:1140353 /DB_XREF=est:yx88f04.s1 /CLONE=IMAGE:268831 /UG=Hs.303090 protein phosphatase 1, regulatory (inhibitor) subunit 5 /FL=gb:NM_005398.1" N26005 "protein phosphatase 1, regulatory subunit 3C" PPP1R3C 5507 NM_005398 0005975 // carbohydrate metabolic process // traceable author statement /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005978 // glycogen biosynthetic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0016311 // dephosphorylation // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005829 // cytosol // traceable author statement 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019903 // protein phosphatase binding // inferred from electronic annotation 204285_s_at AI857639 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI857639 /FEA=EST /DB_XREF=gi:5511255 /DB_XREF=est:wk95g09.x1 /CLONE=IMAGE:2423200 /UG=Hs.96 phorbol-12-myristate-13-acetate-induced protein 1 /FL=gb:NM_021127.1 AI857639 phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 5366 NM_021127 "0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010498 // proteasomal protein catabolic process // inferred from direct assay /// 0010907 // positive regulation of glucose metabolic process // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043331 // response to dsRNA // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 204286_s_at NM_021127 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021127.1 /DEF=Homo sapiens phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1), mRNA. /FEA=mRNA /GEN=PMAIP1 /PROD=phorbol-12-myristate-13-acetate-induced protein1 /DB_XREF=gi:10863922 /UG=Hs.96 phorbol-12-myristate-13-acetate-induced protein 1 /FL=gb:NM_021127.1" NM_021127 phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 5366 NM_021127 "0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from electronic annotation /// 0009411 // response to UV // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010498 // proteasomal protein catabolic process // inferred from direct assay /// 0010907 // positive regulation of glucose metabolic process // inferred from direct assay /// 0010917 // negative regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from mutant phenotype /// 0042771 // intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043331 // response to dsRNA // inferred from direct assay /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0051607 // defense response to virus // inferred from direct assay /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097193 // intrinsic apoptotic signaling pathway // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement" 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction 204287_at NM_004711 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004711.1 /DEF=Homo sapiens synaptogyrin 1 (SYNGR1), mRNA. /FEA=mRNA /GEN=SYNGR1 /PROD=synaptogyrin 1 /DB_XREF=gi:4759199 /UG=Hs.6139 synaptogyrin 1 /FL=gb:NM_004711.1" NM_004711 synaptogyrin 1 SYNGR1 9145 NM_004711 /// NM_145731 /// NM_145738 0006605 // protein targeting // inferred from electronic annotation /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from sequence or structural similarity /// 0048172 // regulation of short-term neuronal synaptic plasticity // inferred from sequence or structural similarity 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 204288_s_at NM_021069 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021069.1 /DEF=Homo sapiens ArgAbl-interacting protein ArgBP2 (ARGBP2), transcript variant 2, mRNA. /FEA=mRNA /GEN=ARGBP2 /PROD=ArgAbl-interacting protein 2, isoform 2 /DB_XREF=gi:10947117 /UG=Hs.278626 ArgAbl-interacting protein ArgBP2 /FL=gb:NM_021069.1 gb:AB018320.1" NM_021069 sorbin and SH3 domain containing 2 SORBS2 8470 NM_001145670 /// NM_001145671 /// NM_001145672 /// NM_001145673 /// NM_001145674 /// NM_001145675 /// NM_001270771 /// NM_003603 /// NM_021069 /// XM_005263302 /// XM_005263305 /// XM_005263306 /// XM_005263307 /// XM_005263308 /// XM_005263310 /// XM_005263311 /// XM_005263312 /// XM_005263313 /// XM_006714345 /// XM_006714346 /// XM_006714347 /// XM_006714348 /// XM_006714349 /// XM_006714350 /// XM_006714351 /// XM_006714352 /// XM_006714353 /// XM_006714354 /// XM_006714355 /// XM_006714356 /// XM_006714357 /// XM_006714358 /// XM_006714359 /// XM_006714360 /// XM_006714361 /// XM_006714362 /// XM_006714363 /// XM_006714364 /// XM_006714365 /// XM_006714366 /// XM_006714367 /// XM_006714368 /// XM_006714369 /// XM_006714370 /// XM_006714371 /// XM_006714372 /// XM_006714373 /// XM_006714374 /// XM_006714375 /// XM_006714376 /// XM_006714377 /// XM_006714378 /// XM_006714379 /// XM_006714380 /// XM_006714381 /// XM_006714382 /// XM_006714383 /// XM_006714384 /// XM_006714385 /// XM_006714386 /// XM_006714387 /// XM_006714388 /// XM_006714389 /// XM_006714390 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204289_at BG399778 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG399778 /FEA=EST /DB_XREF=gi:13293226 /DB_XREF=est:602441382F1 /CLONE=IMAGE:4556900 /UG=Hs.293970 methylmalonate-semialdehyde dehydrogenase /FL=gb:NM_005589.1 gb:BC004909.1 gb:M93405.1 gb:AF148505.1 gb:AF159889.1 BG399778 "aldehyde dehydrogenase 6 family, member A1" ALDH6A1 4329 NM_001278593 /// NM_001278594 /// NM_005589 0006210 // thymine catabolic process // inferred from mutant phenotype /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006574 // valine catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0019859 // thymine metabolic process // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000062 // fatty-acyl-CoA binding // inferred from sequence or structural similarity /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from mutant phenotype /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0018478 // malonate-semialdehyde dehydrogenase (acetylating) activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay" 204290_s_at NM_005589 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005589.1 /DEF=Homo sapiens methylmalonate-semialdehyde dehydrogenase (MMSDH), mRNA. /FEA=mRNA /GEN=MMSDH /PROD=methylmalonate-semialdehyde dehydrogenase /DB_XREF=gi:11095440 /UG=Hs.293970 methylmalonate-semialdehyde dehydrogenase /FL=gb:NM_005589.1 gb:BC004909.1 gb:M93405.1 gb:AF148505.1 gb:AF159889.1" NM_005589 "aldehyde dehydrogenase 6 family, member A1" ALDH6A1 4329 NM_001278593 /// NM_001278594 /// NM_005589 0006210 // thymine catabolic process // inferred from mutant phenotype /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006574 // valine catabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0019859 // thymine metabolic process // inferred from sequence or structural similarity /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // non-traceable author statement /// 0005759 // mitochondrial matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000062 // fatty-acyl-CoA binding // inferred from sequence or structural similarity /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from mutant phenotype /// 0004491 // methylmalonate-semialdehyde dehydrogenase (acylating) activity // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0018478 // malonate-semialdehyde dehydrogenase (acetylating) activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay" 204291_at NM_014803 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014803.1 /DEF=Homo sapiens KIAA0335 gene product (KIAA0335), mRNA. /FEA=mRNA /GEN=KIAA0335 /PROD=KIAA0335 gene product /DB_XREF=gi:7662059 /UG=Hs.29878 KIAA0335 gene product /FL=gb:AB002333.1 gb:NM_014803.1" NM_014803 zinc finger protein 518A ZNF518A 9849 NM_001278524 /// NM_001278525 /// NM_001278526 /// NM_014803 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204292_x_at NM_000455 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000455.1 /DEF=Homo sapiens serinethreonine kinase 11 (Peutz-Jeghers syndrome) (STK11), mRNA. /FEA=mRNA /GEN=STK11 /PROD=serinethreonine protein kinase 11 /DB_XREF=gi:4507270 /UG=Hs.301772 serinethreonine kinase 11 (Peutz-Jeghers syndrome) /FL=gb:U63333.1 gb:AF035625.1 gb:NM_000455.1" NM_000455 serine/threonine kinase 11 STK11 6794 NM_000455 /// XM_005259617 /// XM_005259618 0001558 // regulation of cell growth // inferred from sequence or structural similarity /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0001944 // vasculature development // inferred from sequence or structural similarity /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0010212 // response to ionizing radiation // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0030111 // regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032147 // activation of protein kinase activity // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0033993 // response to lipid // inferred from electronic annotation /// 0036399 // TCR signalosome assembly // inferred from electronic annotation /// 0042304 // regulation of fatty acid biosynthetic process // traceable author statement /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043276 // anoikis // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045059 // positive thymic T cell selection // inferred from electronic annotation /// 0045722 // positive regulation of gluconeogenesis // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation /// 0051896 // regulation of protein kinase B signaling // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060770 // negative regulation of epithelial cell proliferation involved in prostate gland development // inferred from electronic annotation /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from sequence or structural similarity /// 0036398 // TCR signalosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0002039 // p53 binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0030275 // LRR domain binding // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation" 204293_at NM_000199 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000199.1 /DEF=Homo sapiens N-sulfoglucosamine sulfohydrolase (sulfamidase) (SGSH), mRNA. /FEA=mRNA /GEN=SGSH /PROD=N-sulfoglucosamine sulfohydrolase (sulfamidase) /DB_XREF=gi:4506918 /UG=Hs.31074 N-sulfoglucosamine sulfohydrolase (sulfamidase) /FL=gb:U30894.1 gb:NM_000199.1" NM_000199 N-sulfoglucosamine sulfohydrolase SGSH 6448 NM_000199 /// XM_005257582 /// XM_005257583 /// XR_429917 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0006029 // proteoglycan metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement 0005764 // lysosome // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003824 // catalytic activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008484 // sulfuric ester hydrolase activity // inferred from electronic annotation /// 0016250 // N-sulfoglucosamine sulfohydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204294_at NM_000481 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000481.1 /DEF=Homo sapiens aminomethyltransferase (glycine cleavage system protein T) (AMT), mRNA. /FEA=mRNA /GEN=AMT /PROD=aminomethyltransferase (glycine cleavage systemprotein T) /DB_XREF=gi:4502082 /UG=Hs.102 aminomethyltransferase (glycine cleavage system protein T) /FL=gb:D13811.1 gb:NM_000481.1" NM_000481 aminomethyltransferase AMT 275 NM_000481 /// NM_001164710 /// NM_001164711 /// NM_001164712 /// NR_028435 0006546 // glycine catabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 204295_at NM_003172 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003172.1 /DEF=Homo sapiens surfeit 1 (SURF1), mRNA. /FEA=mRNA /GEN=SURF1 /PROD=surfeit 1 /DB_XREF=gi:4507318 /UG=Hs.3196 surfeit 1 /FL=gb:NM_003172.1" NM_003172 surfeit 1 SURF1 6834 NM_001280787 /// NM_003172 /// XM_006717255 /// XM_006717256 0006119 // oxidative phosphorylation // inferred from mutant phenotype /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0008535 // respiratory chain complex IV assembly // traceable author statement /// 0009060 // aerobic respiration // traceable author statement /// 0055114 // oxidation-reduction process // traceable author statement /// 1902600 // hydrogen ion transmembrane transport // inferred from electronic annotation /// 1902600 // hydrogen ion transmembrane transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204296_at NM_021196 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021196.1 /DEF=Homo sapiens sodium bicarbonate transporter 4 (NBC4), mRNA. /FEA=mRNA /GEN=NBC4 /PROD=sodium bicarbonate transporter 4 /DB_XREF=gi:10864004 /UG=Hs.321127 sodium bicarbonate transporter 4 /FL=gb:NM_021196.1" NM_021196 "solute carrier family 4 (sodium bicarbonate cotransporter), member 5" SLC4A5 57835 NM_021196 /// NM_033323 /// NM_133478 /// NM_133479 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0010970 // microtubule-based transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // non-traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // non-traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005869 // dynactin complex // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // non-traceable author statement /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0045502 // dynein binding // inferred from electronic annotation 204297_at NM_002647 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002647.1 /DEF=Homo sapiens phosphoinositide-3-kinase, class 3 (PIK3C3), mRNA. /FEA=mRNA /GEN=PIK3C3 /PROD=phosphoinositide-3-kinase, class 3 /DB_XREF=gi:4505800 /UG=Hs.32971 phosphoinositide-3-kinase, class 3 /FL=gb:NM_002647.1" NM_002647 "phosphatidylinositol 3-kinase, catalytic subunit type 3" PIK3C3 5289 NM_002647 0000045 // autophagic vacuole assembly // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0006914 // autophagy // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from mutant phenotype /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // traceable author statement /// 0043201 // response to leucine // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045022 // early endosome to late endosome transport // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // inferred from electronic annotation /// 0050708 // regulation of protein secretion // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005930 // axoneme // inferred from sequence or structural similarity /// 0005942 // phosphatidylinositol 3-kinase complex // not recorded /// 0016020 // membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from mutant phenotype /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // inferred from electronic annotation" 204298_s_at NM_002317 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002317.1 /DEF=Homo sapiens lysyl oxidase (LOX), mRNA. /FEA=mRNA /GEN=LOX /PROD=lysyl oxidase /DB_XREF=gi:4505008 /UG=Hs.102267 lysyl oxidase /FL=gb:M94054.1 gb:AF039291.1 gb:NM_002317.1" NM_002317 lysyl oxidase LOX 4015 NM_001178102 /// NM_002317 0001568 // blood vessel development // inferred from electronic annotation /// 0006464 // cellular protein modification process // traceable author statement /// 0009725 // response to hormone // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0048251 // elastic fiber assembly // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation "0004720 // protein-lysine 6-oxidase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016641 // oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204299_at NM_021993 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021993.1 /DEF=Homo sapiens TLS-associated serine-arginine protein 2 (TASR2), mRNA. /FEA=mRNA /GEN=TASR2 /PROD=TLS-associated serine-arginine protein 2 /DB_XREF=gi:12056475 /UG=Hs.3530 TLS-associated serine-arginine protein 2 /FL=gb:NM_021993.1 gb:BC005039.1 gb:AF067730.1" NM_021993 serine/arginine-rich splicing factor 10 SRSF10 10772 NM_001191005 /// NM_001191006 /// NM_001191007 /// NM_001191009 /// NM_006625 /// NM_054016 /// NR_034035 /// XM_006710298 /// XM_006710299 /// XM_006710300 /// XM_006710301 "0000244 // spliceosomal tri-snRNP complex assembly // non-traceable author statement /// 0000375 // RNA splicing, via transesterification reactions // inferred from direct assay /// 0000398 // mRNA splicing, via spliceosome // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006376 // mRNA splice site selection // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from direct assay /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay" 0005634 // nucleus // inferred by curator /// 0005654 // nucleoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0050733 // RS domain binding // non-traceable author statement /// 0051082 // unfolded protein binding // non-traceable author statement 204300_at NM_004564 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004564.1 /DEF=Homo sapiens PET112 (yeast homolog)-like (PET112L), mRNA. /FEA=mRNA /GEN=PET112L /PROD=PET112 (yeast homolog)-like /DB_XREF=gi:4758893 /UG=Hs.11127 PET112 (yeast homolog)-like /FL=gb:AF026851.1 gb:NM_004564.1 gb:AF151033.1" NM_004564 PET112 homolog (yeast) PET112 5188 NM_004564 /// XM_005263063 0006412 // translation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0032543 // mitochondrial translation // inferred from mutant phenotype /// 0070681 // glutaminyl-tRNAGln biosynthesis via transamidation // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0030956 // glutamyl-tRNA(Gln) amidotransferase complex // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016884 // carbon-nitrogen ligase activity, with glutamine as amido-N-donor // inferred from electronic annotation /// 0050567 // glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity // inferred from direct assay" 204301_at NM_014867 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014867.1 /DEF=Homo sapiens KIAA0711 gene product (KIAA0711), mRNA. /FEA=mRNA /GEN=KIAA0711 /PROD=KIAA0711 gene product /DB_XREF=gi:7662259 /UG=Hs.5333 KIAA0711 gene product /FL=gb:AB018254.1 gb:NM_014867.1" NM_014867 kelch repeat and BTB (POZ) domain containing 11 KBTBD11 9920 NM_014867 /// XM_005266043 /// XM_005266044 /// XM_005266045 /// XM_006725112 /// XM_006725113 /// XM_006725114 0005515 // protein binding // inferred from electronic annotation 204302_s_at U55962 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:U55962 /FEA=EST /DB_XREF=gi:1354518 /DB_XREF=est:HSU55962 /CLONE=41430 /UG=Hs.64096 KIAA0427 gene product /FL=gb:AB007887.1 gb:NM_014772.1 U55962 CBP80/20-dependent translation initiation factor CTIF 9811 NM_001142397 /// NM_014772 /// XM_005258392 /// XM_006722583 /// XM_006722584 /// XM_006722585 /// XM_006722586 /// XM_006722587 /// XM_006722588 /// XM_006722589 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from mutant phenotype /// 0016070 // RNA metabolic process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204303_s_at NM_014772 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014772.1 /DEF=Homo sapiens KIAA0427 gene product (KIAA0427), mRNA. /FEA=mRNA /GEN=KIAA0427 /PROD=KIAA0427 gene product /DB_XREF=gi:7662111 /UG=Hs.64096 KIAA0427 gene product /FL=gb:AB007887.1 gb:NM_014772.1" NM_014772 CBP80/20-dependent translation initiation factor CTIF 9811 NM_001142397 /// NM_014772 /// XM_005258392 /// XM_006722583 /// XM_006722584 /// XM_006722585 /// XM_006722586 /// XM_006722587 /// XM_006722588 /// XM_006722589 "0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from mutant phenotype /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from mutant phenotype /// 0016070 // RNA metabolic process // inferred from electronic annotation" 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 204304_s_at NM_006017 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006017.1 /DEF=Homo sapiens prominin (mouse)-like 1 (PROML1), mRNA. /FEA=mRNA /GEN=PROML1 /PROD=prominin (mouse)-like 1 /DB_XREF=gi:5174386 /UG=Hs.112360 prominin (mouse)-like 1 /FL=gb:AF027208.1 gb:NM_006017.1" NM_006017 prominin 1 PROM1 8842 NM_001145847 /// NM_001145848 /// NM_001145849 /// NM_001145850 /// NM_001145851 /// NM_001145852 /// NM_006017 /// XM_005248195 /// XM_005248196 /// XM_006713973 /// XM_006713974 0010842 // retina layer formation // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0060042 // retina morphogenesis in camera-type eye // inferred from mutant phenotype /// 0060219 // camera-type eye photoreceptor cell differentiation // inferred from mutant phenotype /// 0060219 // camera-type eye photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype 0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042805 // actinin binding // inferred from direct assay /// 0045296 // cadherin binding // inferred from physical interaction 204305_at NM_005932 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005932.1 /DEF=Homo sapiens mitochondrial intermediate peptidase (MIPEP), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MIPEP /PROD=mitochondrial intermediate peptidase /DB_XREF=gi:5174566 /UG=Hs.68583 mitochondrial intermediate peptidase /FL=gb:U80034.1 gb:NM_005932.1" NM_005932 mitochondrial intermediate peptidase MIPEP 4285 NM_005932 0006508 // proteolysis // inferred from electronic annotation /// 0006627 // protein processing involved in protein targeting to mitochondrion // traceable author statement 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 204306_s_at NM_004357 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004357.1 /DEF=Homo sapiens CD151 antigen (CD151), mRNA. /FEA=mRNA /GEN=CD151 /PROD=CD151 antigen /DB_XREF=gi:4757941 /UG=Hs.75564 CD151 antigen /FL=gb:BC001374.1 gb:D29963.1 gb:NM_004357.1 gb:U14650.1" NM_004357 CD151 molecule (Raph blood group) CD151 977 NM_001039490 /// NM_004357 /// NM_139029 /// NM_139030 0007155 // cell adhesion // non-traceable author statement /// 0016477 // cell migration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204307_at AB002295 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AB002295.1 /DEF=Human mRNA for KIAA0297 gene, partial cds. /FEA=mRNA /GEN=KIAA0297 /DB_XREF=gi:2224534 /UG=Hs.11711 KIAA0329 gene product /FL=gb:AB002327.1 gb:NM_014844.1" AB002295 tectonin beta-propeller repeat containing 2 TECPR2 9895 NM_001172631 /// NM_014844 /// XM_005268246 0006914 // autophagy // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204308_s_at NM_014844 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014844.1 /DEF=Homo sapiens KIAA0329 gene product (KIAA0329), mRNA. /FEA=mRNA /GEN=KIAA0329 /PROD=KIAA0329 gene product /DB_XREF=gi:7662057 /UG=Hs.11711 KIAA0329 gene product /FL=gb:AB002327.1 gb:NM_014844.1" NM_014844 tectonin beta-propeller repeat containing 2 TECPR2 9895 NM_001172631 /// NM_014844 /// XM_005268246 0006914 // autophagy // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 204309_at NM_000781 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000781.1 /DEF=Homo sapiens cytochrome P450, subfamily XIA (cholesterol side chain cleavage) (CYP11A), mRNA. /FEA=mRNA /GEN=CYP11A /PROD=cytochrome P450, subfamily XIA (cholesterol sidechain cleavage) /DB_XREF=gi:4503188 /UG=Hs.76205 cytochrome P450, subfamily XIA (cholesterol side chain cleavage) /FL=gb:M14565.1 gb:NM_000781.1" NM_000781 "cytochrome P450, family 11, subfamily A, polypeptide 1" CYP11A1 1583 NM_000781 /// NM_001099773 /// XM_006720404 /// XM_006720405 0001101 // response to acid // inferred from electronic annotation /// 0006082 // organic acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006700 // C21-steroid hormone biosynthetic process // inferred from direct assay /// 0006700 // C21-steroid hormone biosynthetic process // traceable author statement /// 0006701 // progesterone biosynthetic process // inferred from electronic annotation /// 0006703 // estrogen biosynthetic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007617 // mating behavior // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008203 // cholesterol metabolic process // inferred from sequence or structural similarity /// 0008207 // C21-steroid hormone metabolic process // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016125 // sterol metabolic process // traceable author statement /// 0017085 // response to insecticide // inferred from electronic annotation /// 0018879 // biphenyl metabolic process // inferred from electronic annotation /// 0018894 // dibenzo-p-dioxin metabolic process // inferred from electronic annotation /// 0018958 // phenol-containing compound metabolic process // inferred from electronic annotation /// 0018963 // phthalate metabolic process // inferred from electronic annotation /// 0021549 // cerebellum development // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0033595 // response to genistein // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043279 // response to alkaloid // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050756 // fractalkine metabolic process // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060014 // granulosa cell differentiation // inferred from electronic annotation /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation /// 0060992 // response to fungicide // inferred from electronic annotation /// 0061370 // testosterone biosynthetic process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071276 // cellular response to cadmium ion // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // inferred from electronic annotation /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071375 // cellular response to peptide hormone stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030061 // mitochondrial crista // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation "0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008386 // cholesterol monooxygenase (side-chain-cleaving) activity // inferred from direct assay /// 0008386 // cholesterol monooxygenase (side-chain-cleaving) activity // inferred from sequence or structural similarity /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015485 // cholesterol binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation" 204310_s_at NM_003995 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003995.2 /DEF=Homo sapiens natriuretic peptide receptor Bguanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2), mRNA. /FEA=mRNA /GEN=NPR2 /PROD=natriuretic peptide receptor B precursor,isoform b /DB_XREF=gi:4580421 /UG=Hs.78518 natriuretic peptide receptor Bguanylate cyclase B (atrionatriuretic peptide receptor B) /FL=gb:NM_003995.2" NM_003995 natriuretic peptide receptor 2 NPR2 4882 NM_000907 /// NM_003995 /// XM_005251478 /// XM_005251479 /// XM_006716778 0001503 // ossification // inferred from electronic annotation /// 0006182 // cGMP biosynthetic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007168 // receptor guanylyl cyclase signaling pathway // inferred from direct assay /// 0008217 // regulation of blood pressure // traceable author statement /// 0009190 // cyclic nucleotide biosynthetic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0097011 // cellular response to granulocyte macrophage colony-stimulating factor stimulus // inferred from expression pattern 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004383 // guanylate cyclase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016849 // phosphorus-oxygen lyase activity // inferred from electronic annotation /// 0016941 // natriuretic peptide receptor activity // inferred from direct assay /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation" 204311_at NM_001678 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001678.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, beta 2 polypeptide (ATP1B2), mRNA. /FEA=mRNA /GEN=ATP1B2 /PROD=ATPase, Na+K+ transporting, beta 2 polypeptide /DB_XREF=gi:4502278 /UG=Hs.78854 ATPase, Na+K+ transporting, beta 2 polypeptide /FL=gb:U45945.1 gb:M81181.1 gb:NM_001678.1" NM_001678 "ATPase, Na+/K+ transporting, beta 2 polypeptide" ATP1B2 482 NM_001678 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005890 // sodium:potassium-exchanging ATPase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005391 // sodium:potassium-exchanging ATPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204312_x_at AI655737 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI655737 /FEA=EST /DB_XREF=gi:4739716 /DB_XREF=est:tt14h05.x1 /CLONE=IMAGE:2240793 /UG=Hs.79194 cAMP responsive element binding protein 1 /FL=gb:M27691.1 gb:NM_004379.1 AI655737 cAMP responsive element binding protein 1 CREB1 1385 NM_004379 /// NM_134442 /// XR_241289 /// XR_241290 /// XR_241292 /// XR_427071 "0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204313_s_at AA161486 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA161486 /FEA=EST /DB_XREF=gi:1735796 /DB_XREF=est:zq42d09.s1 /CLONE=IMAGE:632369 /UG=Hs.79194 cAMP responsive element binding protein 1 /FL=gb:M27691.1 gb:NM_004379.1 AA161486 cAMP responsive element binding protein 1 CREB1 1385 NM_004379 /// NM_134442 /// XR_241289 /// XR_241290 /// XR_241292 /// XR_427071 "0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204314_s_at NM_004379 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004379.1 /DEF=Homo sapiens cAMP responsive element binding protein 1 (CREB1), mRNA. /FEA=mRNA /GEN=CREB1 /PROD=cAMP responsive element binding protein 1 /DB_XREF=gi:4758053 /UG=Hs.79194 cAMP responsive element binding protein 1 /FL=gb:M27691.1 gb:NM_004379.1" NM_004379 cAMP responsive element binding protein 1 CREB1 1385 NM_004379 /// NM_134442 /// XR_241289 /// XR_241290 /// XR_241292 /// XR_427071 "0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0008361 // regulation of cell size // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from sequence or structural similarity /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0060428 // lung epithelium development // inferred from electronic annotation /// 0060430 // lung saccule development // inferred from electronic annotation /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation" 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003712 // transcription cofactor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 204315_s_at AI340239 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI340239 /FEA=EST /DB_XREF=gi:4077166 /DB_XREF=est:qx86a08.x1 /CLONE=IMAGE:2009366 /UG=Hs.122552 G-2 and S-phase expressed 1 /FL=gb:AF223408.1 gb:NM_016426.1 AI340239 G-2 and S-phase expressed 1 GTSE1 51512 NM_016426 /// XM_005261627 "0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 204316_at W19676 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:W19676 /FEA=EST /DB_XREF=gi:1295644 /DB_XREF=est:zb36h07.r1 /CLONE=IMAGE:305725 /UG=Hs.82280 regulator of G-protein signalling 10 /FL=gb:NM_002925.2 gb:AF045229.1 W19676 regulator of G-protein signaling 10 RGS10 6001 NM_001005339 /// NM_002925 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 204317_at BF305380 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF305380 /FEA=EST /DB_XREF=gi:11252279 /DB_XREF=est:601892858F1 /CLONE=IMAGE:4138335 /UG=Hs.122552 G-2 and S-phase expressed 1 /FL=gb:AF223408.1 gb:NM_016426.1 BF305380 G-2 and S-phase expressed 1 /// tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase GTSE1 /// TRMU 51512 /// 55687 NM_001008569 /// NM_001008571 /// NM_001282782 /// NM_001282783 /// NM_001282784 /// NM_001282785 /// NM_016426 /// NM_018006 /// NR_104240 /// NR_104241 /// XM_005261627 /// XM_005261678 /// XM_005261681 "0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 204318_s_at NM_016426 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_016426.1 /DEF=Homo sapiens G-2 and S-phase expressed 1 (GTSE1), mRNA. /FEA=mRNA /GEN=GTSE1 /PROD=G-2 and S-phase expressed 1 /DB_XREF=gi:7705291 /UG=Hs.122552 G-2 and S-phase expressed 1 /FL=gb:AF223408.1 gb:NM_016426.1" NM_016426 G-2 and S-phase expressed 1 GTSE1 51512 NM_016426 /// XM_005261627 "0000085 // mitotic G2 phase // non-traceable author statement /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // non-traceable author statement /// 0007017 // microtubule-based process // non-traceable author statement /// 0008033 // tRNA processing // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation" 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // non-traceable author statement /// 0016020 // membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016783 // sulfurtransferase activity // inferred from electronic annotation 204319_s_at NM_002925 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002925.2 /DEF=Homo sapiens regulator of G-protein signalling 10 (RGS10), mRNA. /FEA=mRNA /GEN=RGS10 /PROD=regulator of G-protein signaling 10 /DB_XREF=gi:11184225 /UG=Hs.82280 regulator of G-protein signalling 10 /FL=gb:NM_002925.2 gb:AF045229.1" NM_002925 regulator of G-protein signaling 10 RGS10 6001 NM_001005339 /// NM_002925 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation 204320_at NM_001854 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001854.1 /DEF=Homo sapiens collagen, type XI, alpha 1 (COL11A1), mRNA. /FEA=mRNA /GEN=COL11A1 /PROD=collagen, type XI, alpha 1 /DB_XREF=gi:4502938 /UG=Hs.82772 collagen, type XI, alpha 1 /FL=gb:J04177.1 gb:NM_001854.1" NM_001854 "collagen, type XI, alpha 1" COL11A1 1301 NM_001190709 /// NM_001854 /// NM_080629 /// NM_080630 0001502 // cartilage condensation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0035989 // tendon development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005592 // collagen type XI trimer // inferred from direct assay /// 0005592 // collagen type XI trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation "0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // non-traceable author statement" 204321_at NM_002499 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002499.1 /DEF=Homo sapiens neogenin (chicken) homolog 1 (NEO1), mRNA. /FEA=mRNA /GEN=NEO1 /PROD=neogenin (chicken) homolog 1 /DB_XREF=gi:4505374 /UG=Hs.90408 neogenin (chicken) homolog 1 /FL=gb:U61262.1 gb:U72391.1 gb:NM_002499.1" NM_002499 neogenin 1 NEO1 4756 NM_001172623 /// NM_001172624 /// NM_002499 /// XM_005254408 /// XM_005254410 /// XM_005254411 /// XM_005254412 /// XM_005254413 /// XM_005254414 /// XM_005254415 /// XM_005254416 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0055072 // iron ion homeostasis // inferred from genetic interaction" 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from electronic annotation 204322_at BF002254 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF002254 /FEA=EST /DB_XREF=gi:10702529 /DB_XREF=est:7h02a03.x1 /CLONE=IMAGE:3314764 /UG=Hs.143600 type II Golgi membrane protein /FL=gb:U55853.1 gb:NM_014498.1 BF002254 golgi integral membrane protein 4 GOLIM4 27333 NM_014498 /// XM_005247364 /// XM_005247365 /// XM_005247366 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005801 // cis-Golgi network // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 204323_x_at M61213 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M61213.1 /DEF=Human neurofibromatosis type 1 (NF1) mRNA, complete cds. /FEA=mRNA /GEN=NF1 /PROD=neurofibromatosis protein type 1 /DB_XREF=gi:189162 /UG=Hs.93207 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) /FL=gb:M61213.1 gb:M82814.1 gb:NM_000267.1" M61213 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 "0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 204324_s_at NM_014498 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014498.1 /DEF=Homo sapiens type II Golgi membrane protein (GPP130), mRNA. /FEA=mRNA /GEN=GPP130 /PROD=type II Golgi membrane protein /DB_XREF=gi:7657137 /UG=Hs.143600 type II Golgi membrane protein /FL=gb:U55853.1 gb:NM_014498.1" NM_014498 golgi integral membrane protein 4 GOLIM4 27333 NM_014498 /// XM_005247364 /// XM_005247365 /// XM_005247366 0006810 // transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0005801 // cis-Golgi network // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 204325_s_at NM_000267 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000267.1 /DEF=Homo sapiens neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) (NF1), mRNA. /FEA=mRNA /GEN=NF1 /PROD=neurofibromin /DB_XREF=gi:4557792 /UG=Hs.93207 neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) /FL=gb:M61213.1 gb:M82814.1 gb:NM_000267.1" NM_000267 neurofibromin-like /// neurofibromin 1 LOC101930150 /// NF1 4763 /// 101930150 NM_000267 /// NM_001042492 /// NM_001128147 /// XM_005257983 /// XM_005257984 /// XM_006721922 /// XM_006721923 /// XM_006721924 /// XM_006721925 /// XM_006721926 /// XM_006721927 /// XM_006721928 "0000165 // MAPK cascade // inferred from sequence or structural similarity /// 0001649 // osteoblast differentiation // inferred from sequence or structural similarity /// 0001656 // metanephros development // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from sequence or structural similarity /// 0001953 // negative regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from sequence or structural similarity /// 0007154 // cell communication // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from sequence or structural similarity /// 0007406 // negative regulation of neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from sequence or structural similarity /// 0007422 // peripheral nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008542 // visual learning // inferred from sequence or structural similarity /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 0009451 // RNA modification // inferred from electronic annotation /// 0014044 // Schwann cell development // inferred from sequence or structural similarity /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from sequence or structural similarity /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021897 // forebrain astrocyte development // inferred from sequence or structural similarity /// 0021915 // neural tube development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from sequence or structural similarity /// 0022011 // myelination in peripheral nervous system // inferred from sequence or structural similarity /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // inferred from sequence or structural similarity /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030325 // adrenal gland development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0032318 // regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from direct assay /// 0032320 // positive regulation of Ras GTPase activity // inferred from mutant phenotype /// 0032320 // positive regulation of Ras GTPase activity // inferred from sequence or structural similarity /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0042060 // wound healing // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042992 // negative regulation of transcription factor import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0043409 // negative regulation of MAPK cascade // inferred from mutant phenotype /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043525 // positive regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0043535 // regulation of blood vessel endothelial cell migration // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045124 // regulation of bone resorption // inferred from sequence or structural similarity /// 0045671 // negative regulation of osteoclast differentiation // inferred from electronic annotation /// 0045685 // regulation of glial cell differentiation // inferred from sequence or structural similarity /// 0045762 // positive regulation of adenylate cyclase activity // inferred from sequence or structural similarity /// 0045765 // regulation of angiogenesis // inferred from mutant phenotype /// 0046580 // negative regulation of Ras protein signal transduction // not recorded /// 0046929 // negative regulation of neurotransmitter secretion // inferred from electronic annotation /// 0048147 // negative regulation of fibroblast proliferation // inferred from sequence or structural similarity /// 0048169 // regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0048593 // camera-type eye morphogenesis // inferred from sequence or structural similarity /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0048745 // smooth muscle tissue development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048853 // forebrain morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030425 // dendrite // inferred from direct assay /// 0031235 // intrinsic component of the cytoplasmic side of the plasma membrane // not recorded 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0008429 // phosphatidylethanolamine binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // inferred from direct assay 204326_x_at NM_002450 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002450.1 /DEF=Homo sapiens metallothionein 1L (MT1L), mRNA. /FEA=mRNA /GEN=MT1L /PROD=metallothionein 1L /DB_XREF=gi:4505270 /UG=Hs.94360 metallothionein 1L /FL=gb:NM_002450.1" NM_002450 metallothionein 1X MT1X 4501 NM_005952 0010038 // response to metal ion // traceable author statement /// 0036018 // cellular response to erythropoietin // inferred from expression pattern /// 0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // traceable author statement 204327_s_at N91520 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N91520 /FEA=EST /DB_XREF=gi:1444847 /DB_XREF=est:za91h09.s1 /CLONE=IMAGE:299969 /UG=Hs.9443 zinc finger protein 202 /FL=gb:NM_003455.1 gb:AF027218.1 gb:AF027219.1 N91520 zinc finger protein 202 ZNF202 7753 NM_003455 /// XM_005271659 /// XM_005271660 /// XM_005271661 /// XM_005271662 /// XM_005271663 /// XM_005271664 /// XM_006718900 /// XM_006718901 /// XM_006718902 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204328_at NM_007267 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007267.2 /DEF=Homo sapiens expressed in activated TLAK lymphocytes (LAK-4P), mRNA. /FEA=mRNA /GEN=LAK-4P /PROD=expressed in activated TLAK lymphocytes /DB_XREF=gi:7305226 /UG=Hs.16165 expressed in activated TLAK lymphocytes /FL=gb:AB002405.2 gb:NM_007267.2" NM_007267 transmembrane channel-like 6 TMC6 11322 NM_001127198 /// NM_007267 /// XM_005256995 /// XM_005256996 /// XM_005256997 /// XM_005256998 /// XR_243632 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 204329_s_at N46430 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:N46430 /FEA=EST /DB_XREF=gi:1187596 /DB_XREF=est:yy75g11.s1 /CLONE=IMAGE:279428 /UG=Hs.9443 zinc finger protein 202 /FL=gb:NM_003455.1 gb:AF027218.1 gb:AF027219.1 N46430 zinc finger protein 202 ZNF202 7753 NM_003455 /// XM_005271659 /// XM_005271660 /// XM_005271661 /// XM_005271662 /// XM_005271663 /// XM_005271664 /// XM_006718900 /// XM_006718901 /// XM_006718902 "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // not recorded 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204330_s_at AA587905 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA587905 /FEA=EST /DB_XREF=gi:2402080 /DB_XREF=est:nm71c09.s1 /CLONE=IMAGE:1073680 /UG=Hs.9964 mitochondrial ribosomal protein S12 /FL=gb:NM_021107.1 AA587905 mitochondrial ribosomal protein S12 MRPS12 6183 NM_021107 /// NM_033362 /// NM_033363 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204331_s_at NM_021107 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_021107.1 /DEF=Homo sapiens mitochondrial ribosomal protein S12 (MRPS12), mRNA. /FEA=mRNA /GEN=MRPS12 /PROD=mitochondrial ribosomal protein S12 /DB_XREF=gi:11056055 /UG=Hs.9964 mitochondrial ribosomal protein S12 /FL=gb:NM_021107.1" NM_021107 mitochondrial ribosomal protein S12 MRPS12 6183 NM_021107 /// NM_033362 /// NM_033363 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay 204332_s_at M64073 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:M64073.1 /DEF=Human glycosylasparaginase mRNA, complete cds. /FEA=CDS /PROD=glycosylasparaginase /DB_XREF=gi:183329 /UG=Hs.207776 aspartylglucosaminidase /FL=gb:M64073.1 gb:NM_000027.1" M64073 aspartylglucosaminidase AGA 175 NM_000027 /// NM_001171988 /// NR_033655 /// XM_006714123 0006508 // proteolysis // inferred from electronic annotation /// 0006517 // protein deglycosylation // inferred from direct assay /// 0006517 // protein deglycosylation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from direct assay /// 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation 204333_s_at NM_000027 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000027.1 /DEF=Homo sapiens aspartylglucosaminidase (AGA), mRNA. /FEA=mRNA /GEN=AGA /PROD=aspartylglucosaminidase precursor /DB_XREF=gi:4557272 /UG=Hs.207776 aspartylglucosaminidase /FL=gb:M64073.1 gb:NM_000027.1" NM_000027 aspartylglucosaminidase AGA 175 NM_000027 /// NM_001171988 /// NR_033655 /// XM_006714123 0006508 // proteolysis // inferred from electronic annotation /// 0006517 // protein deglycosylation // inferred from direct assay /// 0006517 // protein deglycosylation // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0051604 // protein maturation // inferred from electronic annotation 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from direct assay /// 0003948 // N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation 204334_at AA488672 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AA488672 /FEA=EST /DB_XREF=gi:2216103 /DB_XREF=est:ab40d10.s1 /CLONE=IMAGE:843283 /UG=Hs.21599 Kruppel-like factor 7 (ubiquitous) /FL=gb:AB015132.1 gb:NM_003709.1 AA488672 Kruppel-like factor 7 (ubiquitous) KLF7 8609 NM_001270942 /// NM_001270943 /// NM_001270944 /// NM_003709 /// NR_073108 /// XM_005246926 /// XM_006712815 /// XM_006712816 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 204335_at NM_018074 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_018074.1 /DEF=Homo sapiens hypothetical protein FLJ10374 (FLJ10374), mRNA. /FEA=mRNA /GEN=FLJ10374 /PROD=hypothetical protein FLJ10374 /DB_XREF=gi:8922381 /UG=Hs.21811 hypothetical protein FLJ10374 /FL=gb:BC000561.1 gb:NM_018074.1" NM_018074 coiled-coil domain containing 94 CCDC94 55702 NM_018074 204336_s_at NM_005873 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005873.1 /DEF=Homo sapiens regulator of G-protein signalling 19 (RGS19), mRNA. /FEA=mRNA /GEN=RGS19 /PROD=G protein signalling regulator 19 /DB_XREF=gi:5031704 /UG=Hs.22698 regulator of G-protein signalling 19 /FL=gb:NM_005873.1" NM_005873 regulator of G-protein signaling 19 RGS19 10287 NM_001039467 /// NM_005873 /// XM_005260182 /// XM_005260183 0006914 // autophagy // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0030136 // clathrin-coated vesicle // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction 204337_at AL514445 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AL514445 /FEA=EST /DB_XREF=gi:12777939 /DB_XREF=est:AL514445 /CLONE=CL0BB010ZF08 (3 prime) /UG=Hs.227571 regulator of G-protein signalling 4 /FL=gb:NM_005613.2 gb:BC000737.1 AL514445 regulator of G-protein signaling 4 RGS4 5999 NM_001102445 /// NM_001113380 /// NM_001113381 /// NM_005613 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 204338_s_at NM_005613 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005613.2 /DEF=Homo sapiens regulator of G-protein signalling 4 (RGS4), mRNA. /FEA=mRNA /GEN=RGS4 /PROD=regulator of G-protein signaling 4 /DB_XREF=gi:11184227 /UG=Hs.227571 regulator of G-protein signalling 4 /FL=gb:NM_005613.2 gb:BC000737.1" NM_005613 regulator of G-protein signaling 4 RGS4 5999 NM_001102445 /// NM_001113380 /// NM_001113381 /// NM_005613 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 204339_s_at BC000737 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC000737.1 /DEF=Homo sapiens, regulator of G-protein signalling 4, clone MGC:2124, mRNA, complete cds. /FEA=mRNA /PROD=regulator of G-protein signalling 4 /DB_XREF=gi:12653888 /UG=Hs.227571 regulator of G-protein signalling 4 /FL=gb:NM_005613.2 gb:BC000737.1" BC000737 regulator of G-protein signaling 4 RGS4 5999 NM_001102445 /// NM_001113380 /// NM_001113381 /// NM_005613 0000188 // inactivation of MAPK activity // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045744 // negative regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0001965 // G-protein alpha-subunit binding // inferred from electronic annotation /// 0005096 // GTPase activator activity // not recorded /// 0005516 // calmodulin binding // traceable author statement 204340_at NM_003492 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003492.1 /DEF=Homo sapiens chromosome X open reading frame 12 (CXORF12), mRNA. /FEA=mRNA /GEN=CXORF12 /PROD=chromosome X open reading frame 12 /DB_XREF=gi:4504738 /UG=Hs.23119 chromosome X open reading frame 12 /FL=gb:NM_003492.1" NM_003492 transmembrane protein 187 TMEM187 8269 NM_003492 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay 204341_at NM_006470 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006470.1 /DEF=Homo sapiens estrogen-responsive B box protein (EBBP), mRNA. /FEA=mRNA /GEN=EBBP /PROD=estrogen-responsive B box protein /DB_XREF=gi:5453643 /UG=Hs.241305 estrogen-responsive B box protein /FL=gb:AF096870.1 gb:NM_006470.1" NM_006470 tripartite motif containing 16 TRIM16 10626 NM_006470 "0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from expression pattern /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0048386 // positive regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from mutant phenotype /// 0060416 // response to growth hormone // inferred from direct assay" 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019966 // interleukin-1 binding // inferred from physical interaction /// 0032089 // NACHT domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204342_at NM_013386 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013386.1 /DEF=Homo sapiens hypothetical protein (DKFZp586G0123), mRNA. /FEA=mRNA /GEN=DKFZp586G0123 /PROD=hypothetical protein /DB_XREF=gi:9558726 /UG=Hs.24713 hypothetical protein /FL=gb:AL050209.1 gb:NM_013386.1" NM_013386 "solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24" SLC25A24 29957 NM_013386 /// NM_213651 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from mutant phenotype /// 0010941 // regulation of cell death // inferred from mutant phenotype /// 0015867 // ATP transport // inferred from mutant phenotype /// 0034599 // cellular response to oxidative stress // inferred from mutant phenotype /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay 0005347 // ATP transmembrane transporter activity // inferred from mutant phenotype /// 0005509 // calcium ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 204343_at NM_001089 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001089.1 /DEF=Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3), mRNA. /FEA=mRNA /GEN=ABCA3 /PROD=ATP-binding cassette, sub-family A member 3 /DB_XREF=gi:4501848 /UG=Hs.26630 ATP-binding cassette, sub-family A (ABC1), member 3 /FL=gb:U78735.1 gb:NM_001089.1" NM_001089 "ATP-binding cassette, sub-family A (ABC1), member 3" ABCA3 21 NM_001089 0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0042493 // response to drug // traceable author statement /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0097208 // alveolar lamellar body // inferred from direct assay /// 0097233 // alveolar lamellar body membrane // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // traceable author statement" 204344_s_at NM_006364 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006364.1 /DEF=Homo sapiens Sec23 (S. cerevisiae) homolog A (SEC23A), mRNA. /FEA=mRNA /GEN=SEC23A /PROD=Sec23 (S. cerevisiae) homolog A /DB_XREF=gi:5454041 /UG=Hs.272927 Sec23 (S. cerevisiae) homolog A /FL=gb:NM_006364.1" NM_006364 Sec23 homolog A (S. cerevisiae) SEC23A 10484 NM_006364 /// XM_005267262 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048208 // COPII vesicle coating // traceable author statement /// 0061024 // membrane organization // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0030868 // smooth endoplasmic reticulum membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 204345_at NM_001856 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001856.1 /DEF=Homo sapiens collagen, type XVI, alpha 1 (COL16A1), mRNA. /FEA=mRNA /GEN=COL16A1 /PROD=collagen, type XVI, alpha 1 /DB_XREF=gi:11386158 /UG=Hs.26208 collagen, type XVI, alpha 1 /FL=gb:NM_001856.1 gb:M92642.1" NM_001856 "collagen, type XVI, alpha 1" COL16A1 1307 NM_001856 /// XM_005270481 0007155 // cell adhesion // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0007565 // female pregnancy // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005597 // collagen type XVI trimer // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement 0005178 // integrin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 204346_s_at NM_007182 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_007182.2 /DEF=Homo sapiens Ras association (RalGDSAF-6) domain family 1 (RASSF1), mRNA. /FEA=mRNA /GEN=RASSF1 /PROD=Ras association (RalGDSAF-6) domain family 1 /DB_XREF=gi:9256633 /UG=Hs.26931 Ras association (RalGDSAF-6) domain family 1 /FL=gb:AF061836.1 gb:AF132676.1 gb:AF040703.2 gb:NM_007182.2" NM_007182 Ras association (RalGDS/AF-6) domain family member 1 RASSF1 11186 NM_001206957 /// NM_007182 /// NM_170712 /// NM_170713 /// NM_170714 /// NM_170715 /// NM_170716 /// NM_170717 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // inferred from direct assay /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 204347_at AI653169 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI653169 /FEA=EST /DB_XREF=gi:4737148 /DB_XREF=est:wb43g08.x1 /CLONE=IMAGE:2308478 /UG=Hs.274691 adenylate kinase 3 /FL=gb:NM_013410.1 AI653169 "adenylate kinase 4 /// adenylate kinase 4, mitochondrial-like" AK4 /// LOC100507855 205 /// 100507855 NM_001005353 /// NM_013410 /// NM_203464 /// XM_003119530 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018885 // carbon tetrachloride metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043643 // tetracycline metabolic process // inferred from electronic annotation /// 0046033 // AMP metabolic process // inferred from direct assay /// 0046034 // ATP metabolic process // inferred from direct assay /// 0046039 // GTP metabolic process // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019201 // nucleotide kinase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation /// 0046899 // nucleoside triphosphate adenylate kinase activity // inferred from direct assay" 204348_s_at NM_013410 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013410.1 /DEF=Homo sapiens adenylate kinase 3 (AK3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=AK3 /PROD=adenylate kinase 3 /DB_XREF=gi:8051578 /UG=Hs.274691 adenylate kinase 3 /FL=gb:NM_013410.1" NM_013410 "adenylate kinase 4 /// adenylate kinase 4, mitochondrial-like" AK4 /// LOC100507855 205 /// 100507855 NM_001005353 /// NM_013410 /// NM_203464 /// XM_003119530 0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006165 // nucleoside diphosphate phosphorylation // inferred from direct assay /// 0006172 // ADP biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018885 // carbon tetrachloride metabolic process // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043643 // tetracycline metabolic process // inferred from electronic annotation /// 0046033 // AMP metabolic process // inferred from direct assay /// 0046034 // ATP metabolic process // inferred from direct assay /// 0046039 // GTP metabolic process // inferred from direct assay /// 0046939 // nucleotide phosphorylation // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004017 // adenylate kinase activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016776 // phosphotransferase activity, phosphate group as acceptor // inferred from electronic annotation /// 0019201 // nucleotide kinase activity // inferred from electronic annotation /// 0019205 // nucleobase-containing compound kinase activity // inferred from electronic annotation /// 0046899 // nucleoside triphosphate adenylate kinase activity // inferred from direct assay" 204349_at BC005250 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC005250.1 /DEF=Homo sapiens, cofactor required for Sp1 transcriptional activation, subunit 9 (33kD), clone MGC:12284, mRNA, complete cds. /FEA=mRNA /PROD=cofactor required for Sp1 transcriptionalactivation, subunit 9 (33kD) /DB_XREF=gi:13528908 /UG=Hs.279902 cofactor required for Sp1 transcriptional activation, subunit 9 (33kD) /FL=gb:BC005250.1 gb:AF031383.1 gb:AF104251.1 gb:NM_004270.1" BC005250 mediator complex subunit 7 MED7 9443 NM_001100816 /// NM_004270 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204350_s_at NM_004270 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004270.1 /DEF=Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 9 (33kD) (CRSP9), mRNA. /FEA=mRNA /GEN=CRSP9 /PROD=cofactor required for Sp1 transcriptionalactivation, subunit 9 (33kD) /DB_XREF=gi:4758063 /UG=Hs.279902 cofactor required for Sp1 transcriptional activation, subunit 9 (33kD) /FL=gb:BC005250.1 gb:AF031383.1 gb:AF104251.1 gb:NM_004270.1" NM_004270 mediator complex subunit 7 MED7 9443 NM_001100816 /// NM_004270 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0019827 // stem cell maintenance // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016592 // mediator complex // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 0001104 // RNA polymerase II transcription cofactor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 204351_at NM_005980 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005980.1 /DEF=Homo sapiens S100 calcium-binding protein P (S100P), mRNA. /FEA=mRNA /GEN=S100P /PROD=S100 calcium-binding protein P /DB_XREF=gi:5174662 /UG=Hs.2962 S100 calcium-binding protein P /FL=gb:NM_005980.1" NM_005980 S100 calcium binding protein P S100P 6286 NM_005980 0010033 // response to organic substance // inferred from expression pattern /// 0043542 // endothelial cell migration // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000287 // magnesium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from physical interaction /// 0050786 // RAGE receptor binding // inferred from electronic annotation 204352_at NM_004619 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004619.1 /DEF=Homo sapiens TNF receptor-associated factor 5 (TRAF5), mRNA. /FEA=mRNA /GEN=TRAF5 /PROD=TNF receptor-associated factor 5 /DB_XREF=gi:11321602 /UG=Hs.29736 TNF receptor-associated factor 5 /FL=gb:NM_004619.1 gb:AB000509.1" NM_004619 TNF receptor-associated factor 5 TRAF5 7188 NM_001033910 /// NM_004619 /// NM_145759 /// XM_005273249 /// XM_006711524 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from expression pattern /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0035631 // CD40 receptor complex // inferred from sequence or structural similarity 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0031996 // thioesterase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204353_s_at BC002923 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:BC002923.1 /DEF=Homo sapiens, clone MGC:10280, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:10280) /DB_XREF=gi:12804138 /UG=Hs.31968 DKFZP586D211 protein /FL=gb:BC002923.1 gb:NM_015450.1" BC002923 protection of telomeres 1 POT1 25913 NM_001042594 /// NM_015450 /// NR_003102 /// NR_003103 /// NR_003104 /// XM_006715917 0000723 // telomere maintenance // traceable author statement /// 0007004 // telomere maintenance via telomerase // inferred from direct assay /// 0016233 // telomere capping // inferred from genetic interaction /// 0016233 // telomere capping // inferred from mutant phenotype /// 0032203 // telomere formation via telomerase // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0051973 // positive regulation of telomerase activity // inferred from direct assay /// 0051974 // negative regulation of telomerase activity // inferred from direct assay /// 0060383 // positive regulation of DNA strand elongation // inferred from direct assay "0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay" 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010521 // telomerase inhibitor activity // inferred from direct assay /// 0017151 // DEAD/H-box RNA helicase binding // inferred from physical interaction /// 0043047 // single-stranded telomeric DNA binding // inferred from direct assay /// 0043047 // single-stranded telomeric DNA binding // inferred from mutant phenotype 204354_at NM_015450 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015450.1 /DEF=Homo sapiens DKFZP586D211 protein (DKFZP586D211), mRNA. /FEA=mRNA /GEN=DKFZP586D211 /PROD=DKFZP586D211 protein /DB_XREF=gi:13123773 /UG=Hs.31968 DKFZP586D211 protein /FL=gb:BC002923.1 gb:NM_015450.1" NM_015450 protection of telomeres 1 POT1 25913 NM_001042594 /// NM_015450 /// NR_003102 /// NR_003103 /// NR_003104 /// XM_006715917 0000723 // telomere maintenance // traceable author statement /// 0007004 // telomere maintenance via telomerase // inferred from direct assay /// 0016233 // telomere capping // inferred from genetic interaction /// 0016233 // telomere capping // inferred from mutant phenotype /// 0032203 // telomere formation via telomerase // inferred from direct assay /// 0032211 // negative regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032212 // positive regulation of telomere maintenance via telomerase // inferred from mutant phenotype /// 0032508 // DNA duplex unwinding // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0051973 // positive regulation of telomerase activity // inferred from direct assay /// 0051974 // negative regulation of telomerase activity // inferred from direct assay /// 0060383 // positive regulation of DNA strand elongation // inferred from direct assay "0000781 // chromosome, telomeric region // inferred from direct assay /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay" 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0010521 // telomerase inhibitor activity // inferred from direct assay /// 0017151 // DEAD/H-box RNA helicase binding // inferred from physical interaction /// 0043047 // single-stranded telomeric DNA binding // inferred from direct assay /// 0043047 // single-stranded telomeric DNA binding // inferred from mutant phenotype 204355_at NM_014966 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014966.1 /DEF=Homo sapiens KIAA0890 protein (KIAA0890), mRNA. /FEA=mRNA /GEN=KIAA0890 /PROD=KIAA0890 protein /DB_XREF=gi:7662361 /UG=Hs.323462 KIAA0890 protein /FL=gb:AB020697.1 gb:NM_014966.1" NM_014966 DEAH (Asp-Glu-Ala-His) box helicase 30 DHX30 22907 NM_014966 /// NM_138614 /// NM_138615 /// NR_075079 /// XM_006713032 /// XM_006713033 0006200 // ATP catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204356_at D26309 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:D26309.1 /DEF=Human mRNA for LIMK (LIM kinase), complete cds. /FEA=mRNA /GEN=limk /PROD=LIMK /DB_XREF=gi:565279 /UG=Hs.36566 LIM domain kinase 1 /FL=gb:D26309.1 gb:NM_002314.2" D26309 LIM domain kinase 1 LIMK1 3984 NM_001204426 /// NM_002314 /// NM_016735 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation" 204357_s_at NM_002314 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002314.2 /DEF=Homo sapiens LIM domain kinase 1 (LIMK1), transcript variant 1, mRNA. /FEA=mRNA /GEN=LIMK1 /PROD=LIM domain kinase 1 isoform 1 /DB_XREF=gi:8051616 /UG=Hs.36566 LIM domain kinase 1 /FL=gb:D26309.1 gb:NM_002314.2" NM_002314 LIM domain kinase 1 LIMK1 3984 NM_001204426 /// NM_002314 /// NM_016735 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation" 204358_s_at AF169676 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AF169676.1 /DEF=Homo sapiens leucine-rich repeat transmembrane protein FLRT2 (FLRT2) mRNA, complete cds. /FEA=mRNA /GEN=FLRT2 /PROD=leucine-rich repeat transmembrane protein FLRT2 /DB_XREF=gi:6808604 /UG=Hs.48998 fibronectin leucine rich transmembrane protein 2 /FL=gb:AB007865.1 gb:AF169676.1 gb:NM_013231.1" AF169676 fibronectin leucine rich transmembrane protein 2 /// uncharacterized LOC100506718 FLRT2 /// LOC100506718 23768 /// 100506718 NM_013231 /// XM_005267489 /// XM_005267490 /// XM_006720095 /// XR_111450 /// XR_172052 /// XR_248023 /// XR_248024 /// XR_248025 /// XR_424524 /// XR_424525 /// XR_424526 /// XR_424527 /// XR_429303 /// XR_429304 /// XR_429305 /// XR_429306 /// XR_429307 /// XR_429308 /// XR_429309 /// XR_433009 /// XR_433010 /// XR_433011 /// XR_433012 /// XR_433013 0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement" 204359_at NM_013231 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_013231.1 /DEF=Homo sapiens fibronectin leucine rich transmembrane protein 2 (FLRT2), mRNA. /FEA=mRNA /GEN=FLRT2 /PROD=fibronectin leucine rich transmembrane protein2 /DB_XREF=gi:7019380 /UG=Hs.48998 fibronectin leucine rich transmembrane protein 2 /FL=gb:AB007865.1 gb:AF169676.1 gb:NM_013231.1" NM_013231 fibronectin leucine rich transmembrane protein 2 /// uncharacterized LOC100506718 FLRT2 /// LOC100506718 23768 /// 100506718 NM_013231 /// XM_005267489 /// XM_005267490 /// XM_006720095 /// XR_111450 /// XR_172052 /// XR_248023 /// XR_248024 /// XR_248025 /// XR_424524 /// XR_424525 /// XR_424526 /// XR_424527 /// XR_429303 /// XR_429304 /// XR_429305 /// XR_429306 /// XR_429307 /// XR_429308 /// XR_429309 /// XR_433009 /// XR_433010 /// XR_433011 /// XR_433012 /// XR_433013 0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement" 204360_s_at NM_000263 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000263.1 /DEF=Homo sapiens N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) (NAGLU), mRNA. /FEA=mRNA /GEN=NAGLU /PROD=N-acetylglucosaminidase, alpha- (Sanfilippodisease IIIB) /DB_XREF=gi:4505326 /UG=Hs.50727 N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) /FL=gb:U43573.1 gb:U40846.1 gb:L78464.1 gb:NM_000263.1" NM_000263 "N-acetylglucosaminidase, alpha" NAGLU 4669 NM_000263 /// XM_006721920 /// XM_006721921 0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045475 // locomotor rhythm // inferred from electronic annotation /// 0046548 // retinal rod cell development // inferred from electronic annotation /// 0060119 // inner ear receptor cell development // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0004561 // alpha-N-acetylglucosaminidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation" 204361_s_at AB014486 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:AB014486.1 /DEF=Homo sapiens mRNA for RA70, complete cds. /FEA=mRNA /GEN=RA70 /PROD=RA70 /DB_XREF=gi:4062959 /UG=Hs.52644 SKAP55 homologue /FL=gb:BC002893.1 gb:AF072166.1 gb:AB014486.1 gb:AF051323.1 gb:NM_003930.1" AB014486 src kinase associated phosphoprotein 2 SKAP2 8935 NM_003930 /// XM_005249901 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 204362_at NM_003930 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003930.1 /DEF=Homo sapiens SKAP55 homologue (SKAP-HOM), mRNA. /FEA=mRNA /GEN=SKAP-HOM /PROD=SKAP55 homologue /DB_XREF=gi:4506962 /UG=Hs.52644 SKAP55 homologue /FL=gb:BC002893.1 gb:AF072166.1 gb:AB014486.1 gb:AF051323.1 gb:NM_003930.1" NM_003930 src kinase associated phosphoprotein 2 SKAP2 8935 NM_003930 /// XM_005249901 0006461 // protein complex assembly // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation 204363_at NM_001993 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001993.2 /DEF=Homo sapiens coagulation factor III (thromboplastin, tissue factor) (F3), mRNA. /FEA=mRNA /GEN=F3 /PROD=coagulation factor III precursor /DB_XREF=gi:10518499 /UG=Hs.62192 coagulation factor III (thromboplastin, tissue factor) /FL=gb:NM_001993.2 gb:J02931.1 gb:M16553.1 gb:M27436.1" NM_001993 "coagulation factor III (thromboplastin, tissue factor)" F3 2152 NM_001178096 /// NM_001993 "0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002541 // activation of plasma proteins involved in acute inflammatory response // inferred from direct assay /// 0002543 // activation of blood coagulation via clotting cascade // inferred by curator /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010641 // positive regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0030335 // positive regulation of cell migration // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from direct assay /// 0050927 // positive regulation of positive chemotaxis // inferred by curator /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype" 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031233 // intrinsic component of external side of plasma membrane // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay 204364_s_at BE535746 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BE535746 /FEA=EST /DB_XREF=gi:9764391 /DB_XREF=est:601060419F1 /CLONE=IMAGE:3446788 /UG=Hs.7358 hypothetical protein FLJ13110 /FL=gb:NM_022912.1 BE535746 receptor accessory protein 1 REEP1 65055 NM_001164730 /// NM_001164731 /// NM_001164732 /// NM_022912 /// XM_005264502 /// XM_005264503 /// XM_005264504 /// XM_005264505 /// XM_006712078 0008219 // cell death // inferred from electronic annotation /// 0051205 // protein insertion into membrane // inferred from direct assay /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0031849 // olfactory receptor binding // inferred from mutant phenotype 204365_s_at NM_022912 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022912.1 /DEF=Homo sapiens hypothetical protein FLJ13110 (FLJ13110), mRNA. /FEA=mRNA /GEN=FLJ13110 /PROD=hypothetical protein FLJ13110 /DB_XREF=gi:12597656 /UG=Hs.7358 hypothetical protein FLJ13110 /FL=gb:NM_022912.1" NM_022912 receptor accessory protein 1 REEP1 65055 NM_001164730 /// NM_001164731 /// NM_001164732 /// NM_022912 /// XM_005264502 /// XM_005264503 /// XM_005264504 /// XM_005264505 /// XM_006712078 0008219 // cell death // inferred from electronic annotation /// 0051205 // protein insertion into membrane // inferred from direct assay /// 0071786 // endoplasmic reticulum tubular network organization // inferred from mutant phenotype 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0031849 // olfactory receptor binding // inferred from mutant phenotype 204366_s_at NM_001521 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_001521.1 /DEF=Homo sapiens general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD) (GTF3C2), mRNA. /FEA=mRNA /GEN=GTF3C2 /PROD=general transcription factor IIIC, polypeptide 2(beta subunit, 110kD) /DB_XREF=gi:4504204 /UG=Hs.75782 general transcription factor IIIC, polypeptide 2 (beta subunit, 110kD) /FL=gb:D13636.1 gb:NM_001521.1" NM_001521 "general transcription factor IIIC, polypeptide 2, beta 110kDa" GTF3C2 2976 NM_001035521 /// NM_001521 /// XM_005264272 /// XM_005264273 "0006351 // transcription, DNA-templated // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // inferred from direct assay /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0042791 // 5S class rRNA transcription from RNA polymerase III type 1 promoter // inferred by curator /// 0042797 // tRNA transcription from RNA polymerase III promoter // inferred by curator" 0000127 // transcription factor TFIIIC complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement 0003677 // DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation 204367_at D28588 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:D28588.1 /DEF=Human mRNA for KIAA0048 gene, complete cds. /FEA=mRNA /GEN=KIAA0048 /DB_XREF=gi:460712 /UG=Hs.77031 Sp2 transcription factor /FL=gb:M97190.1 gb:NM_003110.1 gb:D28588.1" D28588 Sp2 transcription factor SP2 6668 NM_003110 /// XM_006722023 /// XM_006722024 /// XM_006722025 /// XM_006722026 /// XM_006722027 /// XM_006722028 "0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006955 // immune response // traceable author statement /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0048144 // fibroblast proliferation // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation" 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 204368_at NM_005630 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_005630.1 /DEF=Homo sapiens solute carrier family 21 (prostaglandin transporter), member 2 (SLC21A2), mRNA. /FEA=mRNA /GEN=SLC21A2 /PROD=solute carrier family 21 (prostaglandintransporter), member 2 /DB_XREF=gi:5032094 /UG=Hs.83974 solute carrier family 21 (prostaglandin transporter), member 2 /FL=gb:U70867.1 gb:NM_005630.1" NM_005630 "solute carrier organic anion transporter family, member 2A1" SLCO2A1 6578 NM_005630 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // traceable author statement /// 0015732 // prostaglandin transport // inferred from electronic annotation /// 0043252 // sodium-independent organic anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0015132 // prostaglandin transmembrane transporter activity // inferred from electronic annotation 204369_at NM_006218 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006218.1 /DEF=Homo sapiens phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA), mRNA. /FEA=mRNA /GEN=PIK3CA /PROD=phosphoinositide-3-kinase, catalytic, alphapolypeptide /DB_XREF=gi:5453891 /UG=Hs.85701 phosphoinositide-3-kinase, catalytic, alpha polypeptide /FL=gb:U79143.1 gb:NM_006218.1" NM_006218 "phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha" PIK3CA 5290 NM_006218 /// XM_006713658 0001525 // angiogenesis // inferred from electronic annotation /// 0001944 // vasculature development // traceable author statement /// 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006661 // phosphatidylinositol biosynthetic process // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from direct assay /// 0036092 // phosphatidylinositol-3-phosphate biosynthetic process // inferred from electronic annotation /// 0038028 // insulin receptor signaling pathway via phosphatidylinositol 3-kinase // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043542 // endothelial cell migration // traceable author statement /// 0044029 // hypomethylation of CpG island // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0046854 // phosphatidylinositol phosphorylation // inferred from sequence or structural similarity /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050900 // leukocyte migration // traceable author statement /// 0060048 // cardiac muscle contraction // traceable author statement /// 2000270 // negative regulation of fibroblast apoptotic process // inferred from electronic annotation /// 2000653 // regulation of genetic imprinting // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype "0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005942 // phosphatidylinositol 3-kinase complex // inferred from sequence or structural similarity /// 0005943 // 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation" "0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // traceable author statement /// 0016303 // 1-phosphatidylinositol-3-kinase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0030295 // protein kinase activator activity // inferred from electronic annotation /// 0035004 // phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0035004 // phosphatidylinositol 3-kinase activity // traceable author statement /// 0035005 // 1-phosphatidylinositol-4-phosphate 3-kinase activity // not recorded /// 0043560 // insulin receptor substrate binding // inferred from electronic annotation /// 0046934 // phosphatidylinositol-4,5-bisphosphate 3-kinase activity // traceable author statement" 204370_at NM_006831 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_006831.1 /DEF=Homo sapiens ATPGTP-binding protein (HEAB), mRNA. /FEA=mRNA /GEN=HEAB /PROD=ATPGTP-binding protein /DB_XREF=gi:5803028 /UG=Hs.87465 ATPGTP-binding protein /FL=gb:BC000446.1 gb:U73524.1 gb:NM_006831.1" NM_006831 cleavage and polyadenylation factor I subunit 1 CLP1 10978 NM_001142597 /// NM_006831 /// XM_006718425 "0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from direct assay /// 0006388 // tRNA splicing, via endonucleolytic cleavage and ligation // inferred from mutant phenotype /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008033 // tRNA processing // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0021695 // cerebellar cortex development // inferred from mutant phenotype /// 0030423 // targeting of mRNA for destruction involved in RNA interference // inferred from mutant phenotype /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0035087 // siRNA loading onto RISC involved in RNA interference // inferred from direct assay" 0000214 // tRNA-intron endonuclease complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005849 // mRNA cleavage factor complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046404 // ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity // inferred from electronic annotation /// 0051733 // polydeoxyribonucleotide kinase activity // inferred from direct assay /// 0051736 // ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity // inferred from direct assay /// 0051736 // ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity // inferred from mutant phenotype 204371_s_at AI933301 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:AI933301 /FEA=EST /DB_XREF=gi:5672038 /DB_XREF=est:wp65f12.x1 /CLONE=IMAGE:2466671 /UG=Hs.91142 KH-type splicing regulatory protein (FUSE binding protein 2) /FL=gb:U94832.1 gb:NM_003685.1 AI933301 KH-type splicing regulatory protein KHSRP 8570 NM_003685 /// XM_005259668 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204372_s_at NM_003685 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003685.1 /DEF=Homo sapiens KH-type splicing regulatory protein (FUSE binding protein 2) (KHSRP), mRNA. /FEA=mRNA /GEN=KHSRP /PROD=KH-type splicing regulatory protein (FUSEbinding protein 2) /DB_XREF=gi:4504864 /UG=Hs.91142 KH-type splicing regulatory protein (FUSE binding protein 2) /FL=gb:U94832.1 gb:NM_003685.1" NM_003685 KH-type splicing regulatory protein KHSRP 8570 NM_003685 /// XM_005259668 "0000375 // RNA splicing, via transesterification reactions // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation" 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay 204373_s_at NM_014810 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014810.1 /DEF=Homo sapiens KIAA0480 gene product (KIAA0480), mRNA. /FEA=mRNA /GEN=KIAA0480 /PROD=KIAA0480 gene product /DB_XREF=gi:7662155 /UG=Hs.92200 KIAA0480 gene product /FL=gb:AB007949.1 gb:NM_014810.1" NM_014810 centrosomal protein 350kDa CEP350 9857 NM_014810 /// XM_005245638 /// XM_006711666 /// XM_006711667 /// XM_006711668 /// XM_006711669 /// XM_006711670 /// XM_006711671 0034453 // microtubule anchoring // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay 0008017 // microtubule binding // inferred from electronic annotation 204374_s_at BG474736 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BG474736 /FEA=EST /DB_XREF=gi:13407000 /DB_XREF=est:602517557F1 /CLONE=IMAGE:4649007 /UG=Hs.92357 galactokinase 1 /FL=gb:U26401.1 gb:BC001166.1 gb:NM_000154.1 BG474736 galactokinase 1 GALK1 2584 NM_000154 0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019388 // galactose catabolic process // traceable author statement /// 0019402 // galactitol metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0004335 // galactokinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005534 // galactose binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation" 204375_at NM_014718 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014718.1 /DEF=Homo sapiens KIAA0726 gene product (KIAA0726), mRNA. /FEA=mRNA /GEN=KIAA0726 /PROD=KIAA0726 gene product /DB_XREF=gi:7662267 /UG=Hs.107809 KIAA0726 gene product /FL=gb:AB018269.1 gb:NM_014718.1" NM_014718 calsyntenin 3 CLSTN3 9746 NM_014718 /// XM_006719163 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation 204376_at NM_014703 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014703.1 /DEF=Homo sapiens KIAA0800 gene product (KIAA0800), mRNA. /FEA=mRNA /GEN=KIAA0800 /PROD=KIAA0800 gene product /DB_XREF=gi:7662315 /UG=Hs.118738 KIAA0800 gene product /FL=gb:AB018343.1 gb:NM_014703.1" NM_014703 Vpr (HIV-1) binding protein VPRBP 9730 NM_001171904 /// NM_014703 /// XM_005276751 /// XM_005276752 /// XM_005276753 /// XM_005276754 /// XM_005276755 /// XM_006713426 /// XM_006713427 /// XM_006713428 /// XR_254197 /// XR_254198 /// XR_427298 /// XR_427299 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from sequence or structural similarity /// 0035212 // cell competition in a multicellular organism // inferred from mutant phenotype /// 1990245 // histone H2A-T120 phosphorylation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 1990244 // histone kinase activity (H2A-T120 specific) // inferred from direct assay 204377_s_at NM_014703 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_014703.1 /DEF=Homo sapiens KIAA0800 gene product (KIAA0800), mRNA. /FEA=mRNA /GEN=KIAA0800 /PROD=KIAA0800 gene product /DB_XREF=gi:7662315 /UG=Hs.118738 KIAA0800 gene product /FL=gb:AB018343.1 gb:NM_014703.1" NM_014703 Vpr (HIV-1) binding protein VPRBP 9730 NM_001171904 /// NM_014703 /// XM_005276751 /// XM_005276752 /// XM_005276753 /// XM_005276754 /// XM_005276755 /// XM_006713426 /// XM_006713427 /// XM_006713428 /// XR_254197 /// XR_254198 /// XR_427298 /// XR_427299 "0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0033151 // V(D)J recombination // inferred from sequence or structural similarity /// 0035212 // cell competition in a multicellular organism // inferred from mutant phenotype /// 1990245 // histone H2A-T120 phosphorylation // inferred from direct assay" 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // COP9 signalosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 1990244 // histone kinase activity (H2A-T120 specific) // inferred from direct assay 204378_at NM_003657 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003657.1 /DEF=Homo sapiens breast carcinoma amplified sequence 1 (BCAS1), mRNA. /FEA=mRNA /GEN=BCAS1 /PROD=breast carcinoma amplified sequence 1 /DB_XREF=gi:4502372 /UG=Hs.129057 breast carcinoma amplified sequence 1 /FL=gb:AF041260.1 gb:NM_003657.1" NM_003657 breast carcinoma amplified sequence 1 BCAS1 8537 NM_003657 /// XM_005260587 /// XM_005260589 /// XM_005260590 /// XM_005260591 /// XM_005260592 /// XM_005260593 /// XM_005260594 /// XM_005260595 /// XM_005260596 0005737 // cytoplasm // inferred from electronic annotation 204379_s_at NM_000142 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000142.2 /DEF=Homo sapiens fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) (FGFR3), transcript variant 1, mRNA. /FEA=mRNA /GEN=FGFR3 /PROD=fibroblast growth factor receptor 3, isoform 1precursor /DB_XREF=gi:13112046 /UG=Hs.1420 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) /FL=gb:NM_000142.2 gb:M58051.1" NM_000142 fibroblast growth factor receptor 3 FGFR3 2261 NM_000142 /// NM_001163213 /// NM_022965 /// XM_006713868 /// XM_006713869 /// XM_006713870 /// XM_006713871 /// XM_006713872 /// XM_006713873 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001958 // endochondral ossification // traceable author statement /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // traceable author statement /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003416 // endochondral bone growth // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021762 // substantia nigra development // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035988 // chondrocyte proliferation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048640 // negative regulation of developmental growth // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // traceable author statement /// 0060385 // axonogenesis involved in innervation // inferred from electronic annotation /// 0061144 // alveolar secondary septum development // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070977 // bone maturation // inferred from sequence or structural similarity /// 0072148 // epithelial cell fate commitment // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 1902178 // fibroblast growth factor receptor apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction" 204380_s_at M58051 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:M58051.1 /DEF=Human fibroblast growth factor receptor (FGFR3) mRNA, complete cds. /FEA=mRNA /GEN=FGFR3 /PROD=fibroblast growth factor receptor /DB_XREF=gi:182568 /UG=Hs.1420 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) /FL=gb:NM_000142.2 gb:M58051.1" M58051 fibroblast growth factor receptor 3 FGFR3 2261 NM_000142 /// NM_001163213 /// NM_022965 /// XM_006713868 /// XM_006713869 /// XM_006713870 /// XM_006713871 /// XM_006713872 /// XM_006713873 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000165 // MAPK cascade // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0001958 // endochondral ossification // traceable author statement /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // traceable author statement /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0003416 // endochondral bone growth // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021762 // substantia nigra development // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030900 // forebrain development // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035988 // chondrocyte proliferation // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from mutant phenotype /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048640 // negative regulation of developmental growth // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060113 // inner ear receptor cell differentiation // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // traceable author statement /// 0060385 // axonogenesis involved in innervation // inferred from electronic annotation /// 0061144 // alveolar secondary septum development // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070977 // bone maturation // inferred from sequence or structural similarity /// 0072148 // epithelial cell fate commitment // inferred from electronic annotation /// 0090080 // positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 1902178 // fibroblast growth factor receptor apoptotic signaling pathway // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // traceable author statement /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation "0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction" 204381_at NM_002333 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_002333.1 /DEF=Homo sapiens low density lipoprotein receptor-related protein 3 (LRP3), mRNA. /FEA=mRNA /GEN=LRP3 /PROD=low density lipoprotein receptor-related protein3 /DB_XREF=gi:4505014 /UG=Hs.143641 low density lipoprotein receptor-related protein 3 /FL=gb:AB009462.1 gb:NM_002333.1" NM_002333 low density lipoprotein receptor-related protein 3 LRP3 4037 NM_002333 /// XM_005258945 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 204382_at NM_015654 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015654.1 /DEF=Homo sapiens DKFZP564C103 protein (DKFZP564C103), mRNA. /FEA=mRNA /GEN=DKFZP564C103 /PROD=DKFZP564C103 protein /DB_XREF=gi:7661603 /UG=Hs.144058 DKFZP564C103 protein /FL=gb:BC004195.1 gb:BC004225.1 gb:NM_015654.1" NM_015654 "N-acetyltransferase 9 (GCN5-related, putative)" NAT9 26151 NM_015654 /// XM_005257207 /// XM_005257212 /// XM_006721812 /// XM_006721813 /// XM_006721814 /// XM_006721815 /// XM_006721816 /// XR_243644 0008152 // metabolic process // inferred from electronic annotation 0043234 // protein complex // inferred from direct assay "0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation" 204383_at NM_022719 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_022719.1 /DEF=Homo sapiens DiGeorge syndrome critical region gene DGSI (DGSI), mRNA. /FEA=mRNA /GEN=DGSI /PROD=DiGeorge syndrome critical region gene DGSIprotein /DB_XREF=gi:13027629 /UG=Hs.154879 DiGeorge syndrome critical region gene DGSI /FL=gb:NM_022719.1" NM_022719 DiGeorge syndrome critical region gene 14 /// testis-specific serine kinase 2 DGCR14 /// TSSK2 8220 /// 23617 NM_022719 /// NM_053006 /// XM_005261282 /// XM_006724329 /// XM_006724330 /// XM_006724331 "0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay" 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005814 // centriole // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay "0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from sequence or structural similarity /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation" 204384_at NM_004486 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_004486.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 2 (GOLGA2), mRNA. /FEA=mRNA /GEN=GOLGA2 /PROD=golgi autoantigen, golgin subfamily a, 2 /DB_XREF=gi:4758451 /UG=Hs.169055 golgi autoantigen, golgin subfamily a, 2 /FL=gb:L06147.1 gb:NM_004486.1 gb:AF248953.1" NM_004486 golgin A2 GOLGA2 2801 NM_004486 /// XM_005251930 /// XM_005251931 /// XM_005251932 0000278 // mitotic cell cycle // traceable author statement /// 0007021 // tubulin complex assembly // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051645 // Golgi localization // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 204385_at NM_003937 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_003937.1 /DEF=Homo sapiens kynureninase (L-kynurenine hydrolase) (KYNU), mRNA. /FEA=mRNA /GEN=KYNU /PROD=kynureninase (L-kynurenine hydrolase) /DB_XREF=gi:4504936 /UG=Hs.169139 kynureninase (L-kynurenine hydrolase) /FL=gb:U57721.1 gb:NM_003937.1" NM_003937 kynureninase KYNU 8942 NM_001032998 /// NM_001199241 /// NM_003937 0006569 // tryptophan catabolic process // inferred from mutant phenotype /// 0006569 // tryptophan catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0019363 // pyridine nucleotide biosynthetic process // inferred from electronic annotation /// 0019441 // tryptophan catabolic process to kynurenine // inferred from electronic annotation /// 0019442 // tryptophan catabolic process to acetyl-CoA // inferred from electronic annotation /// 0019805 // quinolinate biosynthetic process // inferred from direct assay /// 0034341 // response to interferon-gamma // inferred from direct assay /// 0034354 // 'de novo' NAD biosynthetic process from tryptophan // inferred from electronic annotation /// 0034516 // response to vitamin B6 // inferred from mutant phenotype /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043420 // anthranilate metabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0097053 // L-kynurenine catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0030429 // kynureninase activity // inferred from direct assay /// 0030429 // kynureninase activity // inferred from mutant phenotype /// 0030429 // kynureninase activity // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay 204386_s_at BF303597 Homo sapiens 6-Oct-14 Consensus sequence GenBank Consensus includes gb:BF303597 /FEA=EST /DB_XREF=gi:11250218 /DB_XREF=est:601886230F2 /CLONE=IMAGE:4120446 /UG=Hs.182695 hypothetical protein MGC3243 /FL=gb:BC000002.1 gb:NM_024026.1 BF303597 mitochondrial ribosomal protein L57 MRPL57 78988 NM_024026 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 204387_x_at NM_024026 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_024026.1 /DEF=Homo sapiens hypothetical protein MGC3243 (MGC3243), mRNA. /FEA=mRNA /GEN=MGC3243 /PROD=hypothetical protein MGC3243 /DB_XREF=gi:13128969 /UG=Hs.182695 hypothetical protein MGC3243 /FL=gb:BC000002.1 gb:NM_024026.1" NM_024026 mitochondrial ribosomal protein L57 MRPL57 78988 NM_024026 0006412 // translation // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005761 // mitochondrial ribosome // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 204388_s_at NM_000240 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000240.1 /DEF=Homo sapiens monoamine oxidase A (MAOA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MAOA /PROD=monoamine oxidase A /DB_XREF=gi:4557734 /UG=Hs.183109 monoamine oxidase A /FL=gb:M68840.1 gb:M69226.1 gb:NM_000240.1" NM_000240 monoamine oxidase A MAOA 4128 NM_000240 /// NM_001270458 0006576 // cellular biogenic amine metabolic process // traceable author statement /// 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // traceable author statement /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008131 // primary amine oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204389_at NM_000240 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_000240.1 /DEF=Homo sapiens monoamine oxidase A (MAOA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MAOA /PROD=monoamine oxidase A /DB_XREF=gi:4557734 /UG=Hs.183109 monoamine oxidase A /FL=gb:M68840.1 gb:M69226.1 gb:NM_000240.1" NM_000240 monoamine oxidase A MAOA 4128 NM_000240 /// NM_001270458 0006576 // cellular biogenic amine metabolic process // traceable author statement /// 0006584 // catecholamine metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0007610 // behavior // traceable author statement /// 0042135 // neurotransmitter catabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // traceable author statement /// 0042420 // dopamine catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0008131 // primary amine oxidase activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation 204390_at AF009353 Homo sapiens 6-Oct-14 Consensus sequence GenBank "Consensus includes gb:AF009353.1 /DEF=Homo sapiens transcription intermediary factor 1 (TIF1) mRNA, complete cds. /FEA=CDS /GEN=TIF1 /PROD=transcription intermediary factor 1 /DB_XREF=gi:2267584 /UG=Hs.183858 transcriptional intermediary factor 1 /FL=gb:AF009353.1 gb:AF119042.1 gb:NM_003852.1 gb:NM_015905.1" AF009353 204391_x_at NM_015905 Homo sapiens 6-Oct-14 Exemplar sequence GenBank "gb:NM_015905.1 /DEF=Homo sapiens transcriptional intermediary factor 1 (TIF1), mRNA. /FEA=mRNA /GEN=TIF1 /PROD=transcriptional intermediary factor 1 alpha /DB_XREF=gi:7706233 /UG=Hs.183858 transcriptional intermediary factor 1 /FL=gb:AF009353.1 gb:AF119042.1 gb:NM_003852.1 gb:NM_015905.1" NM_015905 tripartite motif containing 24 TRIM24 8805 NM_003852 /// NM_015905 "0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0042981 // regulation of apoptotic process // inferred from mutant phenotype /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0055074 // calcium ion homeostasis // inferred from electronic annotation /// 0070562 // regulation of vitamin D receptor signaling pathway // inferred from electronic annotation /// 0071391 // cellular response to estrogen stimulus // inferred from direct assay /// 1901796 // regulation of signal transduction by p53 class mediator // inferred from electronic annotation" 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005719 // nuclear euchromatin // inferred from electronic annotation /// 0005726 // perichromatin fibrils // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0002039 // p53 binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation /// 0034056 // estrogen response element binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 00435