{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Table S4 GO annotations"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table S4 GO annotations","index":0,"n_rows":1367,"n_cols":9,"rows_kept":1367,"merged":[[0,0,0,8]],"flags":["formulas_cached_only"]}
["Table S4. GO annotations"]
["Category","ID","Description","p value","p.adjust","q value","gene ID","Count","Enrich_factor"]
["GO-MF","GO:0004674","protein serine/threonine kinase activity",{"v":2.56e-13,"d":"2.56E-13"},{"v":4.55e-11,"d":"4.55E-11"},{"v":2.37e-11,"d":"2.37E-11"},"MAPK14/MAPK8/MAP2K1/RPS6KA1/MAP2K3/RPS6KA4/MAP2K6/MAPK1/ATM/TBK1/PRKAA1/AKT1/EGFR",13,{"v":16.4,"d":"16.40"}]
["GO-MF","GO:0019902","phosphatase binding",{"v":6.46e-13,"d":"6.46E-13"},{"v":5.72e-11,"d":"5.72E-11"},{"v":2.97e-11,"d":"2.97E-11"},"MAPK14/TP53/MAPK1/STAT3/STAT6/TBK1/EIF4EBP1/SMAD2/AKT1/EGFR",10,{"v":29.9,"d":"29.90"}]
["GO-MF","GO:0004712","protein serine/threonine/tyrosine kinase activity",{"v":9.63e-13,"d":"9.63E-13"},{"v":5.72e-11,"d":"5.72E-11"},{"v":2.97e-11,"d":"2.97E-11"},"MAPK14/MAP2K1/RPS6KA1/MAP2K3/MAP2K6/MAPK1/AKT1",7,{"v":90,"d":"90.00"}]
["GO-MF","GO:0004708","MAP kinase kinase activity",{"v":6e-11,"d":"6.00E-11"},{"v":2.67e-09,"d":"2.67E-09"},{"v":1.39e-09,"d":"1.39E-09"},"MAPK14/MAP2K1/MAP2K3/MAP2K6/MAPK1",5,{"v":173,"d":"173.00"}]
["GO-MF","GO:0019903","protein phosphatase binding",{"v":1.12e-10,"d":"1.12E-10"},{"v":4e-09,"d":"4.00E-09"},{"v":2.08e-09,"d":"2.08E-09"},"MAPK14/TP53/STAT3/STAT6/TBK1/EIF4EBP1/AKT1/EGFR",8,{"v":31.6,"d":"31.60"}]
["GO-MF","GO:0004713","protein tyrosine kinase activity",{"v":3.5e-09,"d":"3.50E-09"},{"v":1.04e-07,"d":"1.04E-07"},{"v":5.41e-08,"d":"5.41E-08"},"MAP2K1/MAP2K3/MAP2K6/TYK2/JAK2/ZAP70/EGFR",7,{"v":28.9,"d":"28.90"}]
["GO-MF","GO:0051219","phosphoprotein binding",{"v":3.66e-07,"d":"3.66E-07"},{"v":9.31e-06,"d":"9.31E-06"},{"v":4.85e-06,"d":"4.85E-06"},"PTPN6/PTPN11/MAPK1/ZAP70/TBK1",5,{"v":33.3,"d":"33.30"}]
["GO-MF","GO:0001784","phosphotyrosine residue binding",{"v":7.69e-07,"d":"7.69E-07"},{"v":1.71e-05,"d":"1.71E-05"},{"v":8.9e-06,"d":"8.90E-06"},"PTPN6/PTPN11/MAPK1/ZAP70",4,{"v":55.3,"d":"55.30"}]
["GO-MF","GO:0004707","MAP kinase activity",{"v":1.93e-06,"d":"1.93E-06"},{"v":3.69e-05,"d":"3.69E-05"},{"v":1.92e-05,"d":"1.92E-05"},"MAPK14/MAPK8/MAPK1",3,{"v":119,"d":"119.00"}]
["GO-MF","GO:0045309","protein phosphorylated amino acid binding",{"v":2.07e-06,"d":"2.07E-06"},{"v":3.69e-05,"d":"3.69E-05"},{"v":1.92e-05,"d":"1.92E-05"},"PTPN6/PTPN11/MAPK1/ZAP70",4,{"v":43.4,"d":"43.40"}]
["GO-MF","GO:0001228","DNA-binding transcription activator activity, RNA polymerase II-specific",{"v":1.08e-05,"d":"1.08E-05"},{"v":0.000163,"d":"1.63E-04"},{"v":8.5e-05,"d":"8.50E-05"},"TP53/SMAD4/STAT3/CREB1/STAT6/STAT5A/SMAD2",7,8.82]
["GO-MF","GO:0001216","DNA-binding transcription activator activity",{"v":1.1e-05,"d":"1.10E-05"},{"v":0.000163,"d":"1.63E-04"},{"v":8.5e-05,"d":"8.50E-05"},"TP53/SMAD4/STAT3/CREB1/STAT6/STAT5A/SMAD2",7,{"v":8.8,"d":"8.80"}]
["GO-MF","GO:0051721","protein phosphatase 2A binding",{"v":2.57e-05,"d":"2.57E-05"},{"v":0.000352,"d":"3.52E-04"},{"v":0.000183,"d":"1.83E-04"},"TP53/EIF4EBP1/AKT1",3,{"v":51.8,"d":"51.80"}]
["GO-MF","GO:0140297","DNA-binding transcription factor binding",{"v":3.42e-05,"d":"3.42E-05"},{"v":0.000435,"d":"4.35E-04"},{"v":0.000226,"d":"2.26E-04"},"MAPK14/STAT3/CREB1/NFKBIA/SMAD2/PSMD9",6,9.45]
["GO-MF","GO:0004711","ribosomal protein S6 kinase activity",{"v":6.62e-05,"d":"6.62E-05"},{"v":0.000736,"d":"7.36E-04"},{"v":0.000383,"d":"3.83E-04"},"RPS6KA1/RPS6KA4",2,{"v":158,"d":"158.00"}]
["GO-MF","GO:0031702","type 1 angiotensin receptor binding",{"v":6.62e-05,"d":"6.62E-05"},{"v":0.000736,"d":"7.36E-04"},{"v":0.000383,"d":"3.83E-04"},"TYK2/JAK2",2,{"v":158,"d":"158.00"}]
["GO-MF","GO:0004715","non-membrane spanning protein tyrosine kinase activity",{"v":7.73e-05,"d":"7.73E-05"},{"v":0.00081,"d":"8.10E-04"},{"v":0.000421,"d":"4.21E-04"},"TYK2/JAK2/ZAP70",3,{"v":36.1,"d":"36.10"}]
["GO-MF","GO:0030235","nitric-oxide synthase regulator activity",{"v":8.81e-05,"d":"8.81E-05"},{"v":0.000825,"d":"8.25E-04"},{"v":0.00043,"d":"4.30E-04"},"AKT1/EGFR",2,{"v":138,"d":"138.00"}]
["GO-MF","GO:0031701","angiotensin receptor binding",{"v":8.81e-05,"d":"8.81E-05"},{"v":0.000825,"d":"8.25E-04"},{"v":0.00043,"d":"4.30E-04"},"TYK2/JAK2",2,{"v":138,"d":"138.00"}]
["GO-MF","GO:0005131","growth hormone receptor binding",{"v":0.000113,"d":"1.13E-04"},{"v":0.00101,"d":"1.01E-03"},{"v":0.000524,"d":"5.24E-04"},"TYK2/JAK2",2,{"v":123,"d":"123.00"}]
["GO-MF","GO:0031625","ubiquitin protein ligase binding",{"v":0.00016,"d":"1.60E-04"},{"v":0.00133,"d":"1.33E-03"},{"v":0.000695,"d":"6.95E-04"},"TP53/SMAD5/NFKBIA/SMAD2/EGFR",5,9.53]
["GO-MF","GO:0043560","insulin receptor substrate binding",{"v":0.000172,"d":"1.72E-04"},{"v":0.00133,"d":"1.33E-03"},{"v":0.000695,"d":"6.95E-04"},"PTPN11/JAK2",2,{"v":101,"d":"101.00"}]
["GO-MF","GO:0070411","I-SMAD binding",{"v":0.000172,"d":"1.72E-04"},{"v":0.00133,"d":"1.33E-03"},{"v":0.000695,"d":"6.95E-04"},"SMAD4/SMAD2",2,{"v":101,"d":"101.00"}]
["GO-MF","GO:0044389","ubiquitin-like protein ligase binding",{"v":0.000212,"d":"2.12E-04"},{"v":0.00157,"d":"1.57E-03"},{"v":0.000817,"d":"8.17E-04"},"TP53/SMAD5/NFKBIA/SMAD2/EGFR",5,8.98]
["GO-MF","GO:0051427","hormone receptor binding",{"v":0.000331,"d":"3.31E-04"},{"v":0.00235,"d":"2.35E-03"},{"v":0.00123,"d":"1.23E-03"},"PTPN11/TYK2/STAT3/JAK2",4,{"v":12,"d":"12.00"}]
["GO-MF","GO:0035173","histone kinase activity",{"v":0.000424,"d":"4.24E-04"},{"v":0.0029,"d":"2.90E-03"},{"v":0.00151,"d":"1.51E-03"},"JAK2/PRKAA1",2,{"v":65.1,"d":"65.10"}]
["GO-MF","GO:0051428","peptide hormone receptor binding",{"v":0.000651,"d":"6.51E-04"},{"v":0.00429,"d":"4.29E-03"},{"v":0.00223,"d":"2.23E-03"},"PTPN11/JAK2",2,{"v":52.7,"d":"52.70"}]
["GO-MF","GO:0070412","R-SMAD binding",{"v":0.000783,"d":"7.83E-04"},{"v":0.00498,"d":"4.98E-03"},{"v":0.00259,"d":"2.59E-03"},"SMAD4/SMAD2",2,{"v":48.1,"d":"48.10"}]
["GO-MF","GO:0047485","protein N-terminus binding",{"v":0.00099,"d":"9.90E-04"},{"v":0.00608,"d":"6.08E-03"},{"v":0.00316,"d":"3.16E-03"},"TP53/MAP2K1/ATM",3,{"v":15.2,"d":"15.20"}]
["GO-MF","GO:0035035","histone acetyltransferase binding",{"v":0.00125,"d":"1.25E-03"},{"v":0.0074,"d":"7.40E-03"},{"v":0.00385,"d":"3.85E-03"},"TP53/CREB1",2,{"v":38.1,"d":"38.10"}]
["GO-MF","GO:0061629","RNA polymerase II-specific DNA-binding transcription factor binding",{"v":0.0015,"d":"1.50E-03"},{"v":0.00859,"d":"8.59E-03"},{"v":0.00447,"d":"4.47E-03"},"MAPK14/STAT3/CREB1/NFKBIA",4,7.99]
["GO-MF","GO:0001664","G protein-coupled receptor binding",{"v":0.00156,"d":"1.56E-03"},{"v":0.00866,"d":"8.66E-03"},{"v":0.0045,"d":"4.50E-03"},"PTPN11/TYK2/STAT3/JAK2",4,{"v":7.9,"d":"7.90"}]
["GO-MF","GO:0097718","disordered domain specific binding",{"v":0.00162,"d":"1.62E-03"},{"v":0.00871,"d":"8.71E-03"},{"v":0.00453,"d":"4.53E-03"},"TP53/SMAD2",2,{"v":33.5,"d":"33.50"}]
["GO-MF","GO:0005126","cytokine receptor binding",{"v":0.00168,"d":"1.68E-03"},{"v":0.00881,"d":"8.81E-03"},{"v":0.00458,"d":"4.58E-03"},"TYK2/STAT3/JAK2/SMAD2",4,7.73]
["GO-MF","GO:0042169","SH2 domain binding",{"v":0.00192,"d":"1.92E-03"},{"v":0.00977,"d":"9.77E-03"},{"v":0.00508,"d":"5.08E-03"},"PTPN6/JAK2",2,{"v":30.7,"d":"30.70"}]
["GO-MF","GO:0048156","tau protein binding",{"v":0.00299,"d":"2.99E-03"},{"v":0.0148,"d":"1.48E-02"},{"v":0.00769,"d":"7.69E-03"},"PRKAA1/SMAD2",2,{"v":24.6,"d":"24.60"}]
["GO-MF","GO:0005080","protein kinase C binding",{"v":0.00412,"d":"4.12E-03"},{"v":0.0198,"d":"1.98E-02"},{"v":0.0103,"d":"1.03E-02"},"HSPB1/AKT1",2,{"v":20.9,"d":"20.90"}]
["GO-MF","GO:0008022","protein C-terminus binding",{"v":0.0046,"d":"4.60E-03"},{"v":0.0215,"d":"2.15E-02"},{"v":0.0112,"d":"1.12E-02"},"MAP2K1/JAK2/PRKAA1",3,8.87]
["GO-MF","GO:0001085","RNA polymerase II transcription factor binding",{"v":0.00542,"d":"5.42E-03"},{"v":0.0248,"d":"2.48E-02"},{"v":0.0129,"d":"1.29E-02"},"TP53/SMAD4",2,{"v":18.1,"d":"18.10"}]
["GO-MF","GO:0030971","receptor tyrosine kinase binding",{"v":0.00689,"d":"6.89E-03"},{"v":0.0307,"d":"3.07E-02"},{"v":0.016,"d":"1.60E-02"},"TP53/PTPN11",2,{"v":16,"d":"16.00"}]
["GO-MF","GO:0048273","mitogen-activated protein kinase p38 binding",{"v":0.00901,"d":"9.01E-03"},{"v":0.038,"d":"3.80E-02"},{"v":0.0198,"d":"1.98E-02"},"MAPK14",1,{"v":111,"d":"111.00"}]
["GO-MF","GO:0051525","NFAT protein binding",{"v":0.00901,"d":"9.01E-03"},{"v":0.038,"d":"3.80E-02"},{"v":0.0198,"d":"1.98E-02"},"MAPK14",1,{"v":111,"d":"111.00"}]
["GO-MF","GO:0046332","SMAD binding",{"v":0.00917,"d":"9.17E-03"},{"v":0.038,"d":"3.80E-02"},{"v":0.0198,"d":"1.98E-02"},"SMAD4/SMAD2",2,{"v":13.8,"d":"13.80"}]
["GO-MF","GO:0033613","activating transcription factor binding",{"v":0.0103,"d":"1.03E-02"},{"v":0.0417,"d":"4.17E-02"},{"v":0.0217,"d":"2.17E-02"},"CREB1/SMAD2",2,{"v":13,"d":"13.00"}]
["GO-MF","GO:0005143","interleukin-12 receptor binding",{"v":0.0108,"d":"1.08E-02"},{"v":0.0418,"d":"4.18E-02"},{"v":0.0218,"d":"2.18E-02"},"JAK2",1,{"v":92.2,"d":"92.20"}]
["GO-MF","GO:0035174","histone serine kinase activity",{"v":0.0108,"d":"1.08E-02"},{"v":0.0418,"d":"4.18E-02"},{"v":0.0218,"d":"2.18E-02"},"PRKAA1",1,{"v":92.2,"d":"92.20"}]
["GO-MF","GO:1990782","protein tyrosine kinase binding",{"v":0.0122,"d":"1.22E-02"},{"v":0.0457,"d":"4.57E-02"},{"v":0.0238,"d":"2.38E-02"},"TP53/PTPN11",2,{"v":11.9,"d":"11.90"}]
["GO-MF","GO:0004679","AMP-activated protein kinase activity",{"v":0.0126,"d":"1.26E-02"},{"v":0.0457,"d":"4.57E-02"},{"v":0.0238,"d":"2.38E-02"},"PRKAA1",1,{"v":79,"d":"79.00"}]
["GO-MF","GO:0031730","CCR5 chemokine receptor binding",{"v":0.0126,"d":"1.26E-02"},{"v":0.0457,"d":"4.57E-02"},{"v":0.0238,"d":"2.38E-02"},"STAT3",1,{"v":79,"d":"79.00"}]
["GO-MF","GO:0004725","protein tyrosine phosphatase activity",{"v":0.014,"d":"1.40E-02"},{"v":0.0474,"d":"4.74E-02"},{"v":0.0247,"d":"2.47E-02"},"PTPN6/PTPN11",2,{"v":11.1,"d":"11.10"}]
["GO-MF","GO:0004726","non-membrane spanning protein tyrosine phosphatase activity",{"v":0.0144,"d":"1.44E-02"},{"v":0.0474,"d":"4.74E-02"},{"v":0.0247,"d":"2.47E-02"},"PTPN11",1,{"v":69.1,"d":"69.10"}]
["GO-MF","GO:0017151","DEAD/H-box RNA helicase binding",{"v":0.0144,"d":"1.44E-02"},{"v":0.0474,"d":"4.74E-02"},{"v":0.0247,"d":"2.47E-02"},"SMAD5",1,{"v":69.1,"d":"69.10"}]
["GO-MF","GO:0070878","primary miRNA binding",{"v":0.0144,"d":"1.44E-02"},{"v":0.0474,"d":"4.74E-02"},{"v":0.0247,"d":"2.47E-02"},"SMAD2",1,{"v":69.1,"d":"69.10"}]
["GO-MF","GO:0097371","MDM2/MDM4 family protein binding",{"v":0.0144,"d":"1.44E-02"},{"v":0.0474,"d":"4.74E-02"},{"v":0.0247,"d":"2.47E-02"},"TP53",1,{"v":69.1,"d":"69.10"}]
["GO-CC","GO:0071141","SMAD protein complex",{"v":1.35309096104018e-07,"d":"1.35E-07"},{"v":1.56958551480661e-05,"d":"1.57E-05"},{"v":9.82771329597602e-06,"d":"9.83E-06"},"SMAD4/SMAD5/SMAD2",3,{"v":264.066964285714,"d":"264.07"}]
["GO-CC","GO:0005667","transcription regulator complex",{"v":3.71597678763451e-06,"d":"3.72E-06"},{"v":0.000215526653682802,"d":"2.16E-04"},{"v":0.000134948630708832,"d":"1.35E-04"},"TP53/RBM14/SMAD4/SMAD5/STAT3/CREB1/SMAD2",7,{"v":10.3929969879518,"d":"10.39"}]
["GO-CC","GO:0090575","RNA polymerase II transcription regulator complex",{"v":6.67176101838145e-06,"d":"6.67E-06"},{"v":0.000257974759377416,"d":"2.58E-04"},{"v":0.000161526845708183,"d":"1.62E-04"},"TP53/SMAD4/STAT3/CREB1/SMAD2",5,{"v":18.5589231927711,"d":"18.56"}]
["GO-CC","GO:0000790","nuclear chromatin",{"v":2.75277565700983e-05,"d":"2.75E-05"},{"v":0.000798304940532852,"d":"7.98E-04"},{"v":0.000499846106141259,"d":"5.00E-04"},"TP53/SMAD4/STAT3/CREB1/STAT6/SMAD2",6,{"v":9.83228058510638,"d":"9.83"}]
["GO-CC","GO:0045121","membrane raft",{"v":0.000142473208336253,"d":"1.42E-04"},{"v":0.00279556275180574,"d":"2.80E-03"},{"v":0.00175039773025949,"d":"1.75E-03"},"MAPK1/JAK2/ZAP70/STAT6/EGFR",5,{"v":9.78025793650793,"d":"9.78"}]
["GO-CC","GO:0098857","membrane microdomain",{"v":0.000144598073369262,"d":"1.45E-04"},{"v":0.00279556275180574,"d":"2.80E-03"},{"v":0.00175039773025949,"d":"1.75E-03"},"MAPK1/JAK2/ZAP70/STAT6/EGFR",5,{"v":9.74930775316456,"d":"9.75"}]
["GO-CC","GO:0098589","membrane region",{"v":0.000172042160439905,"d":"1.72E-04"},{"v":0.00285098437300414,"d":"2.85E-03"},{"v":0.00178509910832383,"d":"1.79E-03"},"MAPK1/JAK2/ZAP70/STAT6/EGFR",5,{"v":9.39262576219512,"d":"9.39"}]
["GO-CC","GO:0005819","spindle",{"v":0.000223456333257036,"d":"2.23E-04"},{"v":0.00324011683222702,"d":"3.24E-03"},{"v":0.00202874828878098,"d":"2.03E-03"},"MAPK14/HSPB1/MAPK1/ATM/AKT1",5,{"v":8.87833213256484,"d":"8.88"}]
["GO-CC","GO:0005925","focal adhesion",{"v":0.000454743946118253,"d":"4.55E-04"},{"v":0.00570342290677226,"d":"5.70E-03"},{"v":0.00357110871658154,"d":"3.57E-03"},"MAP2K1/HSPB1/MAPK1/JAK2/EGFR",5,{"v":7.60686728395062,"d":"7.61"}]
["GO-CC","GO:0030055","cell-substrate junction",{"v":0.00049167438851485,"d":"4.92E-04"},{"v":0.00570342290677226,"d":"5.70E-03"},{"v":0.00357110871658154,"d":"3.57E-03"},"MAP2K1/HSPB1/MAPK1/JAK2/EGFR",5,{"v":7.47762439320388,"d":"7.48"}]
["GO-CC","GO:0031983","vesicle lumen",{"v":0.00185130323746025,"d":"1.85E-03"},{"v":0.0195228341404899,"d":"1.95E-02"},{"v":0.0122239161133739,"d":"1.22E-02"},"PTPN6/MAPK14/MAPK1/EGFR",4,{"v":7.53707951070336,"d":"7.54"}]
["GO-CC","GO:0098978","glutamatergic synapse",{"v":0.00234563916697212,"d":"2.35E-03"},{"v":0.0226745119473972,"d":"2.27E-02"},{"v":0.0141972896948313,"d":"1.42E-02"},"MAPK14/STAT3/JAK2/EIF4EBP1",4,{"v":7.06196275071633,"d":"7.06"}]
["GO-CC","GO:0000502","proteasome complex",{"v":0.00468530839545229,"d":"4.69E-03"},{"v":0.0400329922867418,"d":"4.00E-02"},{"v":0.0250660296532231,"d":"2.51E-02"},"HSPB1/PSMD9",2,{"v":19.5605158730159,"d":"19.56"}]
["GO-CC","GO:1905369","endopeptidase complex",{"v":0.00483156803460677,"d":"4.83E-03"},{"v":0.0400329922867418,"d":"4.00E-02"},{"v":0.0250660296532231,"d":"2.51E-02"},"HSPB1/PSMD9",2,{"v":19.2548828125,"d":"19.25"}]
["GO-CC","GO:0005901","caveola",{"v":0.00745205910224348,"d":"7.45E-03"},{"v":0.047489119891191,"d":"4.75E-02"},{"v":0.029734566901018,"d":"2.97E-02"},"MAPK1/JAK2",2,{"v":15.40390625,"d":"15.40"}]
["GO-CC","GO:0005850","eukaryotic translation initiation factor 2 complex",{"v":0.00808934525587612,"d":"8.09E-03"},{"v":0.047489119891191,"d":"4.75E-02"},{"v":0.029734566901018,"d":"2.97E-02"},"EIF2S1",1,{"v":123.23125,"d":"123.23"}]
["GO-CC","GO:0042105","alpha-beta T cell receptor complex",{"v":0.00808934525587612,"d":"8.09E-03"},{"v":0.047489119891191,"d":"4.75E-02"},{"v":0.029734566901018,"d":"2.97E-02"},"PTPN6",1,{"v":123.23125,"d":"123.23"}]
["GO-CC","GO:0097450","astrocyte end-foot",{"v":0.00808934525587612,"d":"8.09E-03"},{"v":0.047489119891191,"d":"4.75E-02"},{"v":0.029734566901018,"d":"2.97E-02"},"EIF2S1",1,{"v":123.23125,"d":"123.23"}]
["GO-CC","GO:0005770","late endosome",{"v":0.00812628677006905,"d":"8.13E-03"},{"v":0.047489119891191,"d":"4.75E-02"},{"v":0.029734566901018,"d":"2.97E-02"},"MAP2K1/MAPK1/EGFR",3,{"v":7.2205810546875,"d":"7.22"}]
["GO-CC","GO:0120111","neuron projection cytoplasm",{"v":0.00818777929158466,"d":"8.19E-03"},{"v":0.047489119891191,"d":"4.75E-02"},{"v":0.029734566901018,"d":"2.97E-02"},"HSPB1/MAPK1",2,{"v":14.6703869047619,"d":"14.67"}]
["GO-BP","GO:0048732","gland development",{"v":3.17e-12,"d":"3.17E-12"},{"v":7.87e-09,"d":"7.87E-09"},{"v":3.06e-09,"d":"3.06E-09"},"MAP2K1/RPS6KA1/SMAD4/MAPK1/ATM/JAK2/CREB1/STAT6/STAT5A/SMAD2/AKT1/EGFR",12,{"v":16.13191244,"d":"16.13"}]
["GO-BP","GO:0062197","cellular response to chemical stress",{"v":7.8e-12,"d":"7.80E-12"},{"v":7.87e-09,"d":"7.87E-09"},{"v":3.06e-09,"d":"3.06E-09"},"MAPK8/TP53/HSPB1/MAPK1/EIF2S1/ATM/JAK2/STAT6/PRKAA1/AKT1/EGFR",11,{"v":18.33660714,"d":"18.34"}]
["GO-BP","GO:0018108","peptidyl-tyrosine phosphorylation",{"v":1.16e-11,"d":"1.16E-11"},{"v":7.87e-09,"d":"7.87E-09"},{"v":3.06e-09,"d":"3.06E-09"},"PTPN6/TP53/MAP2K1/MAP2K3/PTPN11/MAP2K6/TYK2/STAT3/JAK2/ZAP70/EGFR",11,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:0018212","peptidyl-tyrosine modification",{"v":1.26e-11,"d":"1.26E-11"},{"v":7.87e-09,"d":"7.87E-09"},{"v":3.06e-09,"d":"3.06E-09"},"PTPN6/TP53/MAP2K1/MAP2K3/PTPN11/MAP2K6/TYK2/STAT3/JAK2/ZAP70/EGFR",11,{"v":17.53500683,"d":"17.54"}]
["GO-BP","GO:0034599","cellular response to oxidative stress",{"v":4.98e-11,"d":"4.98E-11"},{"v":2.48e-08,"d":"2.48E-08"},{"v":9.64e-09,"d":"9.64E-09"},"MAPK8/TP53/HSPB1/MAPK1/EIF2S1/JAK2/STAT6/PRKAA1/AKT1/EGFR",10,{"v":19.31912252,"d":"19.32"}]
["GO-BP","GO:0032147","activation of protein kinase activity",{"v":1.3e-10,"d":"1.30E-10"},{"v":4.54e-08,"d":"4.54E-08"},{"v":1.76e-08,"d":"1.76E-08"},"MAPK14/MAP2K1/MAP2K3/PTPN11/MAP2K6/MAPK1/JAK2/PRKAA1/AKT1/EGFR",10,{"v":17.52064565,"d":"17.52"}]
["GO-BP","GO:0071902","positive regulation of protein serine/threonine kinase activity",{"v":1.34e-10,"d":"1.34E-10"},{"v":4.54e-08,"d":"4.54E-08"},{"v":1.76e-08,"d":"1.76E-08"},"MAPK14/MAP2K1/MAP2K3/PTPN11/MAP2K6/MAPK1/JAK2/PRKAA1/AKT1/EGFR",10,{"v":17.46818862,"d":"17.47"}]
["GO-BP","GO:0043405","regulation of MAP kinase activity",{"v":1.46e-10,"d":"1.46E-10"},{"v":4.54e-08,"d":"4.54E-08"},{"v":1.76e-08,"d":"1.76E-08"},"PTPN6/MAPK14/MAP2K1/MAP2K3/PTPN11/MAP2K6/MAPK1/JAK2/PRKAA1/EGFR",10,{"v":17.31268546,"d":"17.31"}]
["GO-BP","GO:0043406","positive regulation of MAP kinase activity",{"v":3.4e-10,"d":"3.40E-10"},{"v":9.41e-08,"d":"9.41E-08"},{"v":3.66e-08,"d":"3.66E-08"},"MAPK14/MAP2K1/MAP2K3/PTPN11/MAP2K6/MAPK1/JAK2/PRKAA1/EGFR",9,{"v":20.35247093,"d":"20.35"}]
["GO-BP","GO:1901653","cellular response to peptide",{"v":5.33e-10,"d":"5.33E-10"},{"v":1.33e-07,"d":"1.33E-07"},{"v":5.16e-08,"d":"5.16E-08"},"TP53/PTPN11/STAT3/JAK2/CREB1/STAT6/STAT5A/EIF4EBP1/PRKAA1/AKT1",10,{"v":15.15422078,"d":"15.15"}]
["GO-BP","GO:0018105","peptidyl-serine phosphorylation",{"v":1.25e-09,"d":"1.25E-09"},{"v":2.83e-07,"d":"2.83E-07"},{"v":1.1e-07,"d":"1.10E-07"},"MAPK14/MAPK8/RPS6KA4/MAPK1/ATM/TBK1/PRKAA1/AKT1/EGFR",9,{"v":17.56166388,"d":"17.56"}]
["GO-BP","GO:0007568","aging",{"v":2.33e-09,"d":"2.33E-09"},{"v":4.08e-07,"d":"4.08E-07"},{"v":1.59e-07,"d":"1.59E-07"},"MAPK14/TP53/MAP2K1/MAPK1/EIF2S1/STAT3/ATM/CREB1/AKT1",9,{"v":16.35806075,"d":"16.36"}]
["GO-BP","GO:0071375","cellular response to peptide hormone stimulus",{"v":2.33e-09,"d":"2.33E-09"},{"v":4.08e-07,"d":"4.08E-07"},{"v":1.59e-07,"d":"1.59E-07"},"PTPN11/STAT3/JAK2/CREB1/STAT6/STAT5A/EIF4EBP1/PRKAA1/AKT1",9,{"v":16.35806075,"d":"16.36"}]
["GO-BP","GO:0018209","peptidyl-serine modification",{"v":2.39e-09,"d":"2.39E-09"},{"v":4.08e-07,"d":"4.08E-07"},{"v":1.59e-07,"d":"1.59E-07"},"MAPK14/MAPK8/RPS6KA4/MAPK1/ATM/TBK1/PRKAA1/AKT1/EGFR",9,{"v":16.30725932,"d":"16.31"}]
["GO-BP","GO:0006979","response to oxidative stress",{"v":2.46e-09,"d":"2.46E-09"},{"v":4.08e-07,"d":"4.08E-07"},{"v":1.59e-07,"d":"1.59E-07"},"MAPK8/TP53/HSPB1/MAPK1/EIF2S1/JAK2/STAT6/PRKAA1/AKT1/EGFR",10,{"v":12.93652993,"d":"12.94"}]
["GO-BP","GO:0060416","response to growth hormone",{"v":5.14e-09,"d":"5.14E-09"},{"v":8.01e-07,"d":"8.01E-07"},{"v":3.11e-07,"d":"3.11E-07"},"STAT3/JAK2/STAT6/STAT5A/AKT1",5,{"v":76.76809211,"d":"76.77"}]
["GO-BP","GO:0000187","activation of MAPK activity",{"v":5.86e-09,"d":"5.86E-09"},{"v":8.59e-07,"d":"8.59E-07"},{"v":3.34e-07,"d":"3.34E-07"},"MAPK14/MAP2K1/MAP2K3/PTPN11/MAP2K6/MAPK1/PRKAA1",7,{"v":26.86883224,"d":"26.87"}]
["GO-BP","GO:0060397","growth hormone receptor signaling pathway via JAK-STAT",{"v":7.03e-09,"d":"7.03E-09"},{"v":9.73e-07,"d":"9.73E-07"},{"v":3.78e-07,"d":"3.78E-07"},"STAT3/JAK2/STAT6/STAT5A",4,{"v":166.6964286,"d":"166.70"}]
["GO-BP","GO:0071248","cellular response to metal ion",{"v":2.55e-08,"d":"2.55E-08"},{"v":3.35e-06,"d":"3.35E-06"},{"v":1.3e-06,"d":"1.30E-06"},"MAPK8/MAPK1/EIF2S1/CREB1/PRKAA1/AKT1/EGFR",7,{"v":21.7237367,"d":"21.72"}]
["GO-BP","GO:0043434","response to peptide hormone",{"v":3.31e-08,"d":"3.31E-08"},{"v":4.13e-06,"d":"4.13E-06"},{"v":1.6e-06,"d":"1.60E-06"},"PTPN11/STAT3/JAK2/CREB1/STAT6/STAT5A/EIF4EBP1/PRKAA1/AKT1",9,{"v":12.04343463,"d":"12.04"}]
["GO-BP","GO:0009314","response to radiation",{"v":4.18e-08,"d":"4.18E-08"},{"v":4.79e-06,"d":"4.79E-06"},{"v":1.86e-06,"d":"1.86E-06"},"MAPK14/MAPK8/TP53/EIF2S1/ATM/CREB1/PRKAA1/AKT1/EGFR",9,{"v":11.72084263,"d":"11.72"}]
["GO-BP","GO:1901214","regulation of neuron death",{"v":4.23e-08,"d":"4.23E-08"},{"v":4.79e-06,"d":"4.79E-06"},{"v":1.86e-06,"d":"1.86E-06"},"TP53/EIF2S1/STAT3/ATM/JAK2/CREB1/TBK1/AKT1",8,{"v":14.91214058,"d":"14.91"}]
["GO-BP","GO:0031098","stress-activated protein kinase signaling cascade",{"v":4.44e-08,"d":"4.44E-08"},{"v":4.82e-06,"d":"4.82E-06"},{"v":1.87e-06,"d":"1.87E-06"},"MAPK14/MAPK8/MAP2K1/MAP2K3/MAP2K6/MAPK1/AKT1/EGFR",8,{"v":14.81746032,"d":"14.82"}]
["GO-BP","GO:0010506","regulation of autophagy",{"v":6.07e-08,"d":"6.07E-08"},{"v":5.8e-06,"d":"5.80E-06"},{"v":2.25e-06,"d":"2.25E-06"},"MAPK8/TP53/HSPB1/STAT3/ATM/TBK1/PRKAA1/AKT1",8,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:2000637","positive regulation of gene silencing by miRNA",{"v":6.15e-08,"d":"6.15E-08"},{"v":5.8e-06,"d":"5.80E-06"},{"v":2.25e-06,"d":"2.25E-06"},"TP53/MAP2K1/STAT3/EGFR",4,{"v":101.4673913,"d":"101.47"}]
["GO-BP","GO:0071241","cellular response to inorganic substance",{"v":6.42e-08,"d":"6.42E-08"},{"v":5.8e-06,"d":"5.80E-06"},{"v":2.25e-06,"d":"2.25E-06"},"MAPK8/MAPK1/EIF2S1/CREB1/PRKAA1/AKT1/EGFR",7,{"v":18.99563953,"d":"19.00"}]
["GO-BP","GO:0071214","cellular response to abiotic stimulus",{"v":6.51e-08,"d":"6.51E-08"},{"v":5.8e-06,"d":"5.80E-06"},{"v":2.25e-06,"d":"2.25E-06"},"MAPK14/MAPK8/TP53/PTPN11/EIF2S1/ATM/AKT1/EGFR",8,{"v":14.10120846,"d":"14.10"}]
["GO-BP","GO:0104004","cellular response to environmental stimulus",{"v":6.51e-08,"d":"6.51E-08"},{"v":5.8e-06,"d":"5.80E-06"},{"v":2.25e-06,"d":"2.25E-06"},"MAPK14/MAPK8/TP53/PTPN11/EIF2S1/ATM/AKT1/EGFR",8,{"v":14.10120846,"d":"14.10"}]
["GO-BP","GO:0046887","positive regulation of hormone secretion",{"v":6.9e-08,"d":"6.90E-08"},{"v":5.93e-06,"d":"5.93E-06"},{"v":2.3e-06,"d":"2.30E-06"},"SMAD4/PTPN11/JAK2/CREB1/PSMD9/EGFR",6,{"v":27.56397638,"d":"27.56"}]
["GO-BP","GO:0060148","positive regulation of posttranscriptional gene silencing",{"v":7.37e-08,"d":"7.37E-08"},{"v":5.93e-06,"d":"5.93E-06"},{"v":2.3e-06,"d":"2.30E-06"},"TP53/MAP2K1/STAT3/EGFR",4,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0060396","growth hormone receptor signaling pathway",{"v":7.37e-08,"d":"7.37E-08"},{"v":5.93e-06,"d":"5.93E-06"},{"v":2.3e-06,"d":"2.30E-06"},"STAT3/JAK2/STAT6/STAT5A",4,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0071496","cellular response to external stimulus",{"v":7.83e-08,"d":"7.83E-08"},{"v":6.1e-06,"d":"6.10E-06"},{"v":2.37e-06,"d":"2.37E-06"},"MAPK8/TP53/PTPN11/MAPK1/EIF2S1/PRKAA1/AKT1/EGFR",8,{"v":13.76843658,"d":"13.77"}]
["GO-BP","GO:0071378","cellular response to growth hormone stimulus",{"v":8.76e-08,"d":"8.76E-08"},{"v":6.62e-06,"d":"6.62E-06"},{"v":2.57e-06,"d":"2.57E-06"},"STAT3/JAK2/STAT6/STAT5A",4,93.35]
["GO-BP","GO:0070997","neuron death",{"v":9.57e-08,"d":"9.57E-08"},{"v":7.02e-06,"d":"7.02E-06"},{"v":2.73e-06,"d":"2.73E-06"},"TP53/EIF2S1/STAT3/ATM/JAK2/CREB1/TBK1/AKT1",8,{"v":13.41235632,"d":"13.41"}]
["GO-BP","GO:0031667","response to nutrient levels",{"v":1.05e-07,"d":"1.05E-07"},{"v":7.48e-06,"d":"7.48E-06"},{"v":2.91e-06,"d":"2.91E-06"},"MAPK8/TP53/MAPK1/EIF2S1/CREB1/EIF4EBP1/PRKAA1/AKT1/EGFR",9,{"v":10.52292084,"d":"10.52"}]
["GO-BP","GO:0001666","response to hypoxia",{"v":1.22e-07,"d":"1.22E-07"},{"v":8.42e-06,"d":"8.42E-06"},{"v":3.27e-06,"d":"3.27E-06"},"TP53/SMAD4/ATM/CREB1/EIF4EBP1/PRKAA1/AKT1/PSMD9",8,{"v":13.00139276,"d":"13.00"}]
["GO-BP","GO:0009411","response to UV",{"v":1.29e-07,"d":"1.29E-07"},{"v":8.66e-06,"d":"8.66E-06"},{"v":3.36e-06,"d":"3.36E-06"},"MAPK8/TP53/EIF2S1/PRKAA1/AKT1/EGFR",6,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:0006606","protein import into nucleus",{"v":1.4e-07,"d":"1.40E-07"},{"v":8.93e-06,"d":"8.93E-06"},{"v":3.47e-06,"d":"3.47E-06"},"MAPK14/TP53/MAPK1/STAT3/NFKBIA/AKT1",6,{"v":24.4798951,"d":"24.48"}]
["GO-BP","GO:0030879","mammary gland development",{"v":1.4e-07,"d":"1.40E-07"},{"v":8.93e-06,"d":"8.93E-06"},{"v":3.47e-06,"d":"3.47E-06"},"MAPK1/JAK2/CREB1/STAT6/STAT5A/AKT1",6,{"v":24.4798951,"d":"24.48"}]
["GO-BP","GO:0036293","response to decreased oxygen levels",{"v":1.53e-07,"d":"1.53E-07"},{"v":9.46e-06,"d":"9.46E-06"},{"v":3.67e-06,"d":"3.67E-06"},"TP53/SMAD4/ATM/CREB1/EIF4EBP1/PRKAA1/AKT1/PSMD9",8,{"v":12.61486486,"d":"12.61"}]
["GO-BP","GO:0035264","multicellular organism growth",{"v":1.58e-07,"d":"1.58E-07"},{"v":9.46e-06,"d":"9.46E-06"},{"v":3.67e-06,"d":"3.67E-06"},"TP53/PTPN11/STAT3/ATM/CREB1/STAT5A",6,{"v":23.97688356,"d":"23.98"}]
["GO-BP","GO:0060020","Bergmann glial cell differentiation",{"v":1.59e-07,"d":"1.59E-07"},{"v":9.46e-06,"d":"9.46E-06"},{"v":3.67e-06,"d":"3.67E-06"},"MAP2K1/PTPN11/MAPK1",3,{"v":250.0446429,"d":"250.04"}]
["GO-BP","GO:0070102","interleukin-6-mediated signaling pathway",{"v":1.64e-07,"d":"1.64E-07"},{"v":9.49e-06,"d":"9.49E-06"},{"v":3.69e-06,"d":"3.69E-06"},"SMAD4/PTPN11/STAT3/JAK2",4,{"v":80.47413793,"d":"80.47"}]
["GO-BP","GO:0070482","response to oxygen levels",{"v":2.47e-07,"d":"2.47E-07"},{"v":1.38e-05,"d":"1.38E-05"},{"v":5.36e-06,"d":"5.36E-06"},"TP53/SMAD4/ATM/CREB1/EIF4EBP1/PRKAA1/AKT1/PSMD9",8,{"v":11.8464467,"d":"11.85"}]
["GO-BP","GO:0048708","astrocyte differentiation",{"v":2.49e-07,"d":"2.49E-07"},{"v":1.38e-05,"d":"1.38E-05"},{"v":5.36e-06,"d":"5.36E-06"},"MAP2K1/PTPN11/MAPK1/STAT3/EGFR",5,{"v":36.01466049,"d":"36.01"}]
["GO-BP","GO:1903532","positive regulation of secretion by cell",{"v":2.94e-07,"d":"2.94E-07"},{"v":1.59e-05,"d":"1.59E-05"},{"v":6.18e-06,"d":"6.18E-06"},"MAPK14/SMAD4/PTPN11/MAP2K6/JAK2/CREB1/PSMD9/EGFR",8,{"v":11.58188586,"d":"11.58"}]
["GO-BP","GO:0051170","import into nucleus",{"v":3.03e-07,"d":"3.03E-07"},{"v":1.61e-05,"d":"1.61E-05"},{"v":6.25e-06,"d":"6.25E-06"},"MAPK14/TP53/MAPK1/STAT3/NFKBIA/AKT1",6,{"v":21.47622699,"d":"21.48"}]
["GO-BP","GO:0034614","cellular response to reactive oxygen species",{"v":3.62e-07,"d":"3.62E-07"},{"v":1.88e-05,"d":"1.88E-05"},{"v":7.31e-06,"d":"7.31E-06"},"MAPK8/MAPK1/STAT6/PRKAA1/AKT1/EGFR",6,{"v":20.83705357,"d":"20.84"}]
["GO-BP","GO:0030099","myeloid cell differentiation",{"v":3.74e-07,"d":"3.74E-07"},{"v":1.9e-05,"d":"1.90E-05"},{"v":7.39e-06,"d":"7.39E-06"},"PTPN6/MAPK14/PTPN11/SMAD5/STAT3/JAK2/CREB1/NFKBIA",8,{"v":11.21995192,"d":"11.22"}]
["GO-BP","GO:0038155","interleukin-23-mediated signaling pathway",{"v":3.82e-07,"d":"3.82E-07"},{"v":1.9e-05,"d":"1.90E-05"},{"v":7.39e-06,"d":"7.39E-06"},"TYK2/STAT3/JAK2",3,{"v":194.4791667,"d":"194.48"}]
["GO-BP","GO:0030324","lung development",{"v":4.16e-07,"d":"4.16E-07"},{"v":2.03e-05,"d":"2.03E-05"},{"v":7.9e-06,"d":"7.90E-06"},"MAP2K1/MAPK1/CREB1/EIF4EBP1/SMAD2/EGFR",6,{"v":20.35247093,"d":"20.35"}]
["GO-BP","GO:0051403","stress-activated MAPK cascade",{"v":4.46e-07,"d":"4.46E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAPK14/MAPK8/MAP2K1/MAP2K3/MAPK1/AKT1/EGFR",7,{"v":14.27993881,"d":"14.28"}]
["GO-BP","GO:0071276","cellular response to cadmium ion",{"v":4.51e-07,"d":"4.51E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAPK8/MAPK1/AKT1/EGFR",4,{"v":63.07432432,"d":"63.07"}]
["GO-BP","GO:0051047","positive regulation of secretion",{"v":4.64e-07,"d":"4.64E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAPK14/SMAD4/PTPN11/MAP2K6/JAK2/CREB1/PSMD9/EGFR",8,{"v":10.90537383,"d":"10.91"}]
["GO-BP","GO:0030323","respiratory tube development",{"v":4.76e-07,"d":"4.76E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAP2K1/MAPK1/CREB1/EIF4EBP1/SMAD2/EGFR",6,{"v":19.88991477,"d":"19.89"}]
["GO-BP","GO:0048608","reproductive structure development",{"v":4.89e-07,"d":"4.89E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAPK14/MAP2K1/SMAD4/PTPN11/MAPK1/ATM/AKT1/EGFR",8,{"v":10.82946636,"d":"10.83"}]
["GO-BP","GO:0042063","gliogenesis",{"v":4.9e-07,"d":"4.90E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAP2K1/PTPN11/MAPK1/STAT3/CREB1/AKT1/EGFR",7,{"v":14.08297414,"d":"14.08"}]
["GO-BP","GO:0051090","regulation of DNA-binding transcription factor activity",{"v":4.98e-07,"d":"4.98E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAPK14/MAPK8/RPS6KA4/MAPK1/STAT3/JAK2/NFKBIA/AKT1",8,{"v":10.80439815,"d":"10.80"}]
["GO-BP","GO:0016572","histone phosphorylation",{"v":5.04e-07,"d":"5.04E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"RPS6KA4/ATM/JAK2/PRKAA1",4,{"v":61.41447368,"d":"61.41"}]
["GO-BP","GO:0050673","epithelial cell proliferation",{"v":5.15e-07,"d":"5.15E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAP2K1/RPS6KA1/MAPK1/STAT3/STAT6/STAT5A/AKT1/EGFR",8,{"v":10.75460829,"d":"10.75"}]
["GO-BP","GO:0061458","reproductive system development",{"v":5.15e-07,"d":"5.15E-07"},{"v":2.11e-05,"d":"2.11E-05"},{"v":8.18e-06,"d":"8.18E-06"},"MAPK14/MAP2K1/SMAD4/PTPN11/MAPK1/ATM/AKT1/EGFR",8,{"v":10.75460829,"d":"10.75"}]
["GO-BP","GO:1903800","positive regulation of production of miRNAs involved in gene silencing by miRNA",{"v":5.44e-07,"d":"5.44E-07"},{"v":2.19e-05,"d":"2.19E-05"},{"v":8.5e-06,"d":"8.50E-06"},"TP53/MAP2K1/EGFR",3,{"v":175.03125,"d":"175.03"}]
["GO-BP","GO:0051222","positive regulation of protein transport",{"v":5.72e-07,"d":"5.72E-07"},{"v":2.26e-05,"d":"2.26E-05"},{"v":8.79e-06,"d":"8.79E-06"},"MAPK14/MAPK8/TP53/MAPK1/JAK2/PRKAA1/PSMD9/EGFR",8,{"v":10.60795455,"d":"10.61"}]
["GO-BP","GO:0016570","histone modification",{"v":7.24e-07,"d":"7.24E-07"},{"v":2.78e-05,"d":"2.78E-05"},{"v":1.08e-05,"d":"1.08E-05"},"MAPK8/TP53/RBM14/SMAD4/RPS6KA4/ATM/JAK2/PRKAA1",8,{"v":10.280837,"d":"10.28"}]
["GO-BP","GO:0046879","hormone secretion",{"v":7.34e-07,"d":"7.34E-07"},{"v":2.78e-05,"d":"2.78E-05"},{"v":1.08e-05,"d":"1.08E-05"},"SMAD4/PTPN11/JAK2/CREB1/SMAD2/PSMD9/EGFR",7,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0070106","interleukin-27-mediated signaling pathway",{"v":7.48e-07,"d":"7.48E-07"},{"v":2.78e-05,"d":"2.78E-05"},{"v":1.08e-05,"d":"1.08E-05"},"TYK2/STAT3/JAK2",3,{"v":159.1193182,"d":"159.12"}]
["GO-BP","GO:1904951","positive regulation of establishment of protein localization",{"v":7.48e-07,"d":"7.48E-07"},{"v":2.78e-05,"d":"2.78E-05"},{"v":1.08e-05,"d":"1.08E-05"},"MAPK14/MAPK8/TP53/MAPK1/JAK2/PRKAA1/PSMD9/EGFR",8,{"v":10.23574561,"d":"10.24"}]
["GO-BP","GO:0042594","response to starvation",{"v":7.7e-07,"d":"7.70E-07"},{"v":2.82e-05,"d":"2.82E-05"},{"v":1.1e-05,"d":"1.10E-05"},"MAPK8/TP53/MAPK1/EIF2S1/EIF4EBP1/PRKAA1",6,{"v":18.32787958,"d":"18.33"}]
["GO-BP","GO:2000379","positive regulation of reactive oxygen species metabolic process",{"v":7.9e-07,"d":"7.90E-07"},{"v":2.83e-05,"d":"2.83E-05"},{"v":1.1e-05,"d":"1.10E-05"},"MAPK14/TP53/JAK2/AKT1/EGFR",5,{"v":28.59987745,"d":"28.60"}]
["GO-BP","GO:0017038","protein import",{"v":7.94e-07,"d":"7.94E-07"},{"v":2.83e-05,"d":"2.83E-05"},{"v":1.1e-05,"d":"1.10E-05"},"MAPK14/TP53/MAPK1/STAT3/NFKBIA/AKT1",6,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:0009416","response to light stimulus",{"v":8.35e-07,"d":"8.35E-07"},{"v":2.93e-05,"d":"2.93E-05"},{"v":1.14e-05,"d":"1.14E-05"},"MAPK8/TP53/EIF2S1/CREB1/PRKAA1/AKT1/EGFR",7,{"v":13.00656847,"d":"13.01"}]
["GO-BP","GO:0001819","positive regulation of cytokine production",{"v":8.53e-07,"d":"8.53E-07"},{"v":2.95e-05,"d":"2.95E-05"},{"v":1.15e-05,"d":"1.15E-05"},"MAPK14/HSPB1/PTPN11/STAT3/JAK2/CREB1/STAT6/TBK1",8,{"v":10.05926724,"d":"10.06"}]
["GO-BP","GO:2000377","regulation of reactive oxygen species metabolic process",{"v":8.69e-07,"d":"8.69E-07"},{"v":2.97e-05,"d":"2.97E-05"},{"v":1.15e-05,"d":"1.15E-05"},"MAPK14/TP53/STAT3/JAK2/AKT1/EGFR",6,{"v":17.95192308,"d":"17.95"}]
["GO-BP","GO:0009914","hormone transport",{"v":8.9e-07,"d":"8.90E-07"},{"v":3e-05,"d":"3.00E-05"},{"v":1.16e-05,"d":"1.16E-05"},"SMAD4/PTPN11/JAK2/CREB1/SMAD2/PSMD9/EGFR",7,{"v":12.88347792,"d":"12.88"}]
["GO-BP","GO:0060541","respiratory system development",{"v":9.5e-07,"d":"9.50E-07"},{"v":3.16e-05,"d":"3.16E-05"},{"v":1.23e-05,"d":"1.23E-05"},"MAP2K1/MAPK1/CREB1/EIF4EBP1/SMAD2/EGFR",6,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:0016569","covalent chromatin modification",{"v":1e-06,"d":"1.00E-06"},{"v":3.28e-05,"d":"3.28E-05"},{"v":1.28e-05,"d":"1.28E-05"},"MAPK8/TP53/RBM14/SMAD4/RPS6KA4/ATM/JAK2/PRKAA1",8,{"v":9.847046414,"d":"9.85"}]
["GO-BP","GO:1903829","positive regulation of cellular protein localization",{"v":1.03e-06,"d":"1.03E-06"},{"v":3.3e-05,"d":"3.30E-05"},{"v":1.28e-05,"d":"1.28E-05"},"MAPK14/MAPK8/TP53/MAPK1/PRKAA1/AKT1/EGFR",7,{"v":12.60513117,"d":"12.61"}]
["GO-BP","GO:0034248","regulation of cellular amide metabolic process",{"v":1.03e-06,"d":"1.03E-06"},{"v":3.3e-05,"d":"3.30E-05"},{"v":1.28e-05,"d":"1.28E-05"},"RPS6KA1/HSPB1/MAPK1/EIF2S1/STAT3/EIF4EBP1/PRKAA1/AKT1",8,{"v":9.805672269,"d":"9.81"}]
["GO-BP","GO:0035196","production of miRNAs involved in gene silencing by miRNA",{"v":1.1e-06,"d":"1.10E-06"},{"v":3.39e-05,"d":"3.39E-05"},{"v":1.32e-05,"d":"1.32E-05"},"TP53/MAP2K1/SMAD2/EGFR",4,{"v":50.73369565,"d":"50.73"}]
["GO-BP","GO:0071354","cellular response to interleukin-6",{"v":1.1e-06,"d":"1.10E-06"},{"v":3.39e-05,"d":"3.39E-05"},{"v":1.32e-05,"d":"1.32E-05"},"SMAD4/PTPN11/STAT3/JAK2",4,{"v":50.73369565,"d":"50.73"}]
["GO-BP","GO:1990928","response to amino acid starvation",{"v":1.1e-06,"d":"1.10E-06"},{"v":3.39e-05,"d":"3.39E-05"},{"v":1.32e-05,"d":"1.32E-05"},"MAPK8/MAPK1/EIF2S1/EIF4EBP1",4,{"v":50.73369565,"d":"50.73"}]
["GO-BP","GO:0070849","response to epidermal growth factor",{"v":1.2e-06,"d":"1.20E-06"},{"v":3.63e-05,"d":"3.63E-05"},{"v":1.41e-05,"d":"1.41E-05"},"PTPN11/MAPK1/AKT1/EGFR",4,{"v":49.65425532,"d":"49.65"}]
["GO-BP","GO:0048871","multicellular organismal homeostasis",{"v":1.21e-06,"d":"1.21E-06"},{"v":3.63e-05,"d":"3.63E-05"},{"v":1.41e-05,"d":"1.41E-05"},"HSPB1/PTPN11/MAP2K6/STAT3/JAK2/STAT6/PRKAA1/EGFR",8,{"v":9.603909465,"d":"9.60"}]
["GO-BP","GO:0009612","response to mechanical stimulus",{"v":1.34e-06,"d":"1.34E-06"},{"v":3.97e-05,"d":"3.97E-05"},{"v":1.54e-05,"d":"1.54E-05"},"MAPK14/MAPK8/PTPN11/NFKBIA/AKT1/EGFR",6,{"v":16.66964286,"d":"16.67"}]
["GO-BP","GO:0042035","regulation of cytokine biosynthetic process",{"v":1.37e-06,"d":"1.37E-06"},{"v":4.02e-05,"d":"4.02E-05"},{"v":1.56e-05,"d":"1.56E-05"},"HSPB1/MAP2K3/STAT3/JAK2/TBK1",5,{"v":25.58936404,"d":"25.59"}]
["GO-BP","GO:0006914","autophagy",{"v":1.41e-06,"d":"1.41E-06"},{"v":4.03e-05,"d":"4.03E-05"},{"v":1.57e-05,"d":"1.57E-05"},"MAPK8/TP53/HSPB1/STAT3/ATM/TBK1/PRKAA1/AKT1",8,{"v":9.410282258,"d":"9.41"}]
["GO-BP","GO:0061919","process utilizing autophagic mechanism",{"v":1.41e-06,"d":"1.41E-06"},{"v":4.03e-05,"d":"4.03E-05"},{"v":1.57e-05,"d":"1.57E-05"},"MAPK8/TP53/HSPB1/STAT3/ATM/TBK1/PRKAA1/AKT1",8,{"v":9.410282258,"d":"9.41"}]
["GO-BP","GO:0006913","nucleocytoplasmic transport",{"v":1.51e-06,"d":"1.51E-06"},{"v":4.27e-05,"d":"4.27E-05"},{"v":1.66e-05,"d":"1.66E-05"},"MAPK14/TP53/PTPN11/MAPK1/STAT3/NFKBIA/AKT1",7,{"v":11.90688776,"d":"11.91"}]
["GO-BP","GO:0070741","response to interleukin-6",{"v":1.55e-06,"d":"1.55E-06"},{"v":4.34e-05,"d":"4.34E-05"},{"v":1.68e-05,"d":"1.68E-05"},"SMAD4/PTPN11/STAT3/JAK2",4,{"v":46.675,"d":"46.68"}]
["GO-BP","GO:0051169","nuclear transport",{"v":1.6e-06,"d":"1.60E-06"},{"v":4.42e-05,"d":"4.42E-05"},{"v":1.72e-05,"d":"1.72E-05"},"MAPK14/TP53/PTPN11/MAPK1/STAT3/NFKBIA/AKT1",7,{"v":11.80364884,"d":"11.80"}]
["GO-BP","GO:0010001","glial cell differentiation",{"v":1.66e-06,"d":"1.66E-06"},{"v":4.48e-05,"d":"4.48E-05"},{"v":1.74e-05,"d":"1.74E-05"},"MAP2K1/PTPN11/MAPK1/STAT3/AKT1/EGFR",6,{"v":16.05791284,"d":"16.06"}]
["GO-BP","GO:0031050","dsRNA processing",{"v":1.68e-06,"d":"1.68E-06"},{"v":4.48e-05,"d":"4.48E-05"},{"v":1.74e-05,"d":"1.74E-05"},"TP53/MAP2K1/SMAD2/EGFR",4,{"v":45.75980392,"d":"45.76"}]
["GO-BP","GO:0070918","production of small RNA involved in gene silencing by RNA",{"v":1.68e-06,"d":"1.68E-06"},{"v":4.48e-05,"d":"4.48E-05"},{"v":1.74e-05,"d":"1.74E-05"},"TP53/MAP2K1/SMAD2/EGFR",4,{"v":45.75980392,"d":"45.76"}]
["GO-BP","GO:0007178","transmembrane receptor protein serine/threonine kinase signaling pathway",{"v":1.69e-06,"d":"1.69E-06"},{"v":4.48e-05,"d":"4.48E-05"},{"v":1.74e-05,"d":"1.74E-05"},"MAPK14/TP53/RBM14/SMAD4/SMAD5/CREB1/SMAD2",7,{"v":11.70218481,"d":"11.70"}]
["GO-BP","GO:0042089","cytokine biosynthetic process",{"v":2e-06,"d":"2.00E-06"},{"v":5.24e-05,"d":"5.24E-05"},{"v":2.04e-05,"d":"2.04E-05"},"HSPB1/MAP2K3/STAT3/JAK2/TBK1",5,{"v":23.71697154,"d":"23.72"}]
["GO-BP","GO:0042107","cytokine metabolic process",{"v":2.08e-06,"d":"2.08E-06"},{"v":5.4e-05,"d":"5.40E-05"},{"v":2.1e-05,"d":"2.10E-05"},"HSPB1/MAP2K3/STAT3/JAK2/TBK1",5,{"v":23.52570565,"d":"23.53"}]
["GO-BP","GO:0010038","response to metal ion",{"v":2.16e-06,"d":"2.16E-06"},{"v":5.54e-05,"d":"5.54E-05"},{"v":2.15e-05,"d":"2.15E-05"},"MAPK8/MAPK1/EIF2S1/CREB1/PRKAA1/AKT1/EGFR",7,{"v":11.28194061,"d":"11.28"}]
["GO-BP","GO:0018107","peptidyl-threonine phosphorylation",{"v":2.25e-06,"d":"2.25E-06"},{"v":5.72e-05,"d":"5.72E-05"},{"v":2.22e-05,"d":"2.22E-05"},"MAPK8/MAP2K1/MAPK1/TBK1/AKT1",5,{"v":23.15228175,"d":"23.15"}]
["GO-BP","GO:0035270","endocrine system development",{"v":2.34e-06,"d":"2.34E-06"},{"v":5.89e-05,"d":"5.89E-05"},{"v":2.29e-05,"d":"2.29E-05"},"MAP2K1/MAPK1/CREB1/SMAD2/AKT1",5,{"v":22.96998031,"d":"22.97"}]
["GO-BP","GO:0000302","response to reactive oxygen species",{"v":2.39e-06,"d":"2.39E-06"},{"v":5.95e-05,"d":"5.95E-05"},{"v":2.31e-05,"d":"2.31E-05"},"MAPK8/MAPK1/STAT6/PRKAA1/AKT1/EGFR",6,{"v":15.08890086,"d":"15.09"}]
["GO-BP","GO:0032386","regulation of intracellular transport",{"v":2.49e-06,"d":"2.49E-06"},{"v":6.15e-05,"d":"6.15E-05"},{"v":2.39e-05,"d":"2.39E-05"},"MAPK14/MAPK8/TP53/MAP2K1/PTPN11/MAPK1/PRKAA1",7,{"v":11.03800676,"d":"11.04"}]
["GO-BP","GO:0046777","protein autophosphorylation",{"v":2.57e-06,"d":"2.57E-06"},{"v":6.26e-05,"d":"6.26E-05"},{"v":2.43e-05,"d":"2.43E-05"},"EIF2S1/ATM/JAK2/ZAP70/AKT1/EGFR",6,{"v":14.8962766,"d":"14.90"}]
["GO-BP","GO:0001701","in utero embryonic development",{"v":2.63e-06,"d":"2.63E-06"},{"v":6.26e-05,"d":"6.26E-05"},{"v":2.43e-05,"d":"2.43E-05"},"TP53/MAP2K1/SMAD4/MAPK1/SMAD2/AKT1/EGFR",7,{"v":10.94922922,"d":"10.95"}]
["GO-BP","GO:0051098","regulation of binding",{"v":2.63e-06,"d":"2.63E-06"},{"v":6.26e-05,"d":"6.26E-05"},{"v":2.43e-05,"d":"2.43E-05"},"MAPK8/SMAD4/EIF2S1/JAK2/NFKBIA/SMAD2/AKT1",7,{"v":10.94922922,"d":"10.95"}]
["GO-BP","GO:0071216","cellular response to biotic stimulus",{"v":2.63e-06,"d":"2.63E-06"},{"v":6.26e-05,"d":"6.26E-05"},{"v":2.43e-05,"d":"2.43E-05"},"MAPK14/MAPK8/TP53/MAPK1/NFKBIA/AKT1",6,{"v":14.83315678,"d":"14.83"}]
["GO-BP","GO:0031663","lipopolysaccharide-mediated signaling pathway",{"v":2.83e-06,"d":"2.83E-06"},{"v":6.6e-05,"d":"6.60E-05"},{"v":2.57e-05,"d":"2.57E-05"},"MAPK14/MAPK1/NFKBIA/AKT1",4,{"v":40.23706897,"d":"40.24"}]
["GO-BP","GO:0033002","muscle cell proliferation",{"v":2.83e-06,"d":"2.83E-06"},{"v":6.6e-05,"d":"6.60E-05"},{"v":2.57e-05,"d":"2.57E-05"},"MAPK14/MAPK1/STAT3/JAK2/AKT1/EGFR",6,{"v":14.64696653,"d":"14.65"}]
["GO-BP","GO:0018210","peptidyl-threonine modification",{"v":3.05e-06,"d":"3.05E-06"},{"v":7.03e-05,"d":"7.03E-05"},{"v":2.73e-05,"d":"2.73E-05"},"MAPK8/MAP2K1/MAPK1/TBK1/AKT1",5,{"v":21.77005597,"d":"21.77"}]
["GO-BP","GO:0009266","response to temperature stimulus",{"v":3.12e-06,"d":"3.12E-06"},{"v":7.13e-05,"d":"7.13E-05"},{"v":2.77e-05,"d":"2.77E-05"},"MAPK1/EIF2S1/ATM/NFKBIA/PRKAA1/AKT1",6,{"v":14.4058642,"d":"14.41"}]
["GO-BP","GO:0048872","homeostasis of number of cells",{"v":3.35e-06,"d":"3.35E-06"},{"v":7.59e-05,"d":"7.59E-05"},{"v":2.95e-05,"d":"2.95E-05"},"MAPK14/PTPN11/SMAD5/STAT3/JAK2/AKT1",6,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:0033157","regulation of intracellular protein transport",{"v":3.67e-06,"d":"3.67E-06"},{"v":8.25e-05,"d":"8.25E-05"},{"v":3.21e-05,"d":"3.21E-05"},"MAPK14/MAPK8/TP53/PTPN11/MAPK1/PRKAA1",6,{"v":14.0025,"d":"14.00"}]
["GO-BP","GO:0050867","positive regulation of cell activation",{"v":3.77e-06,"d":"3.77E-06"},{"v":8.4e-05,"d":"8.40E-05"},{"v":3.26e-05,"d":"3.26E-05"},"PTPN6/RPS6KA1/PTPN11/JAK2/ZAP70/STAT6/AKT1",7,{"v":10.36564086,"d":"10.37"}]
["GO-BP","GO:0046686","response to cadmium ion",{"v":3.94e-06,"d":"3.94E-06"},{"v":8.7e-05,"d":"8.70E-05"},{"v":3.38e-05,"d":"3.38E-05"},"MAPK8/MAPK1/AKT1/EGFR",4,{"v":37.04365079,"d":"37.04"}]
["GO-BP","GO:0031056","regulation of histone modification",{"v":4.19e-06,"d":"4.19E-06"},{"v":9.13e-05,"d":"9.13E-05"},{"v":3.55e-05,"d":"3.55E-05"},"MAPK8/TP53/SMAD4/RPS6KA4/ATM",5,{"v":20.39991259,"d":"20.40"}]
["GO-BP","GO:0050730","regulation of peptidyl-tyrosine phosphorylation",{"v":4.21e-06,"d":"4.21E-06"},{"v":9.13e-05,"d":"9.13E-05"},{"v":3.55e-05,"d":"3.55E-05"},"PTPN6/TP53/PTPN11/STAT3/JAK2/EGFR",6,{"v":13.67431641,"d":"13.67"}]
["GO-BP","GO:1903798","regulation of production of miRNAs involved in gene silencing by miRNA",{"v":4.35e-06,"d":"4.35E-06"},{"v":9.35e-05,"d":"9.35E-05"},{"v":3.63e-05,"d":"3.63E-05"},"TP53/MAP2K1/EGFR",3,{"v":92.12171053,"d":"92.12"}]
["GO-BP","GO:0034504","protein localization to nucleus",{"v":4.81e-06,"d":"4.81E-06"},{"v":0.000101652,"d":"1.02E-04"},{"v":3.95e-05,"d":"3.95E-05"},"MAPK14/TP53/MAPK1/STAT3/NFKBIA/AKT1",6,{"v":13.36116412,"d":"13.36"}]
["GO-BP","GO:0046883","regulation of hormone secretion",{"v":4.81e-06,"d":"4.81E-06"},{"v":0.000101652,"d":"1.02E-04"},{"v":3.95e-05,"d":"3.95E-05"},"SMAD4/PTPN11/JAK2/CREB1/PSMD9/EGFR",6,{"v":13.36116412,"d":"13.36"}]
["GO-BP","GO:0014065","phosphatidylinositol 3-kinase signaling",{"v":4.96e-06,"d":"4.96E-06"},{"v":0.000103846,"d":"1.04E-04"},{"v":4.03e-05,"d":"4.03E-05"},"PTPN6/MAPK1/JAK2/AKT1/EGFR",5,{"v":19.71072635,"d":"19.71"}]
["GO-BP","GO:0042108","positive regulation of cytokine biosynthetic process",{"v":5.05e-06,"d":"5.05E-06"},{"v":0.000104903,"d":"1.05E-04"},{"v":4.08e-05,"d":"4.08E-05"},"HSPB1/STAT3/JAK2/TBK1",4,{"v":34.83208955,"d":"34.83"}]
["GO-BP","GO:0009267","cellular response to starvation",{"v":5.12e-06,"d":"5.12E-06"},{"v":0.000105548,"d":"1.06E-04"},{"v":4.1e-05,"d":"4.10E-05"},"MAPK8/TP53/MAPK1/EIF2S1/PRKAA1",5,{"v":19.5784396,"d":"19.58"}]
["GO-BP","GO:0035924","cellular response to vascular endothelial growth factor stimulus",{"v":5.36e-06,"d":"5.36E-06"},{"v":0.000109501,"d":"1.10E-04"},{"v":4.25e-05,"d":"4.25E-05"},"MAPK14/HSPB1/MAP2K3/AKT1",4,{"v":34.31985294,"d":"34.32"}]
["GO-BP","GO:0001890","placenta development",{"v":5.65e-06,"d":"5.65E-06"},{"v":0.000113531,"d":"1.14E-04"},{"v":4.41e-05,"d":"4.41E-05"},"MAPK14/MAP2K1/MAPK1/AKT1/EGFR",5,{"v":19.19202303,"d":"19.19"}]
["GO-BP","GO:0016202","regulation of striated muscle tissue development",{"v":5.65e-06,"d":"5.65E-06"},{"v":0.000113531,"d":"1.14E-04"},{"v":4.41e-05,"d":"4.41E-05"},"MAPK14/SMAD4/MAPK1/CREB1/PRKAA1",5,{"v":19.19202303,"d":"19.19"}]
["GO-BP","GO:0045927","positive regulation of growth",{"v":5.72e-06,"d":"5.72E-06"},{"v":0.000114035,"d":"1.14E-04"},{"v":4.43e-05,"d":"4.43E-05"},"MAPK14/RPS6KA1/MAPK1/CREB1/AKT1/EGFR",6,{"v":12.96527778,"d":"12.97"}]
["GO-BP","GO:0045165","cell fate commitment",{"v":5.84e-06,"d":"5.84E-06"},{"v":0.000115552,"d":"1.16E-04"},{"v":4.49e-05,"d":"4.49E-05"},"TP53/SMAD4/SMAD5/STAT3/STAT6/SMAD2",6,{"v":12.91743542,"d":"12.92"}]
["GO-BP","GO:0070920","regulation of production of small RNA involved in gene silencing by RNA",{"v":5.96e-06,"d":"5.96E-06"},{"v":0.000116931,"d":"1.17E-04"},{"v":4.54e-05,"d":"4.54E-05"},"TP53/MAP2K1/EGFR",3,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0060395","SMAD protein signal transduction",{"v":6.02e-06,"d":"6.02E-06"},{"v":0.000117223,"d":"1.17E-04"},{"v":4.55e-05,"d":"4.55E-05"},"RBM14/SMAD4/SMAD5/SMAD2",4,{"v":33.33928571,"d":"33.34"}]
["GO-BP","GO:0006417","regulation of translation",{"v":6.11e-06,"d":"6.11E-06"},{"v":0.000118031,"d":"1.18E-04"},{"v":4.59e-05,"d":"4.59E-05"},"RPS6KA1/HSPB1/MAPK1/EIF2S1/STAT3/EIF4EBP1/AKT1",7,{"v":9.632222877,"d":"9.63"}]
["GO-BP","GO:1901861","regulation of muscle tissue development",{"v":6.21e-06,"d":"6.21E-06"},{"v":0.00011913,"d":"1.19E-04"},{"v":4.63e-05,"d":"4.63E-05"},"MAPK14/SMAD4/MAPK1/CREB1/PRKAA1",5,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:0048634","regulation of muscle organ development",{"v":6.41e-06,"d":"6.41E-06"},{"v":0.000121988,"d":"1.22E-04"},{"v":4.74e-05,"d":"4.74E-05"},"MAPK14/SMAD4/MAPK1/CREB1/PRKAA1",5,{"v":18.69991987,"d":"18.70"}]
["GO-BP","GO:0061180","mammary gland epithelium development",{"v":6.74e-06,"d":"6.74E-06"},{"v":0.000127237,"d":"1.27E-04"},{"v":4.94e-05,"d":"4.94E-05"},"MAPK1/JAK2/STAT6/AKT1",4,{"v":32.41319444,"d":"32.41"}]
["GO-BP","GO:1901522","positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus",{"v":6.89e-06,"d":"6.89E-06"},{"v":0.000128345,"d":"1.28E-04"},{"v":4.99e-05,"d":"4.99E-05"},"TP53/SMAD4/SMAD5",3,{"v":79.55965909,"d":"79.56"}]
["GO-BP","GO:0000082","G1/S transition of mitotic cell cycle",{"v":6.9e-06,"d":"6.90E-06"},{"v":0.000128345,"d":"1.28E-04"},{"v":4.99e-05,"d":"4.99E-05"},"PTPN6/TP53/ATM/EIF4EBP1/AKT1/EGFR",6,{"v":12.54704301,"d":"12.55"}]
["GO-BP","GO:0072593","reactive oxygen species metabolic process",{"v":7.64e-06,"d":"7.64E-06"},{"v":0.000141007,"d":"1.41E-04"},{"v":5.48e-05,"d":"5.48E-05"},"MAPK14/TP53/STAT3/JAK2/AKT1/EGFR",6,{"v":12.32614437,"d":"12.33"}]
["GO-BP","GO:0071356","cellular response to tumor necrosis factor",{"v":8.77e-06,"d":"8.77E-06"},{"v":0.000160838,"d":"1.61E-04"},{"v":6.25e-05,"d":"6.25E-05"},"MAPK14/MAPK1/JAK2/NFKBIA/AKT1/PSMD9",6,{"v":12.02963918,"d":"12.03"}]
["GO-BP","GO:0051100","negative regulation of binding",{"v":9.46e-06,"d":"9.46E-06"},{"v":0.000171334,"d":"1.71E-04"},{"v":6.66e-05,"d":"6.66E-05"},"MAPK8/EIF2S1/JAK2/NFKBIA/AKT1",5,{"v":17.2614645,"d":"17.26"}]
["GO-BP","GO:0048511","rhythmic process",{"v":9.48e-06,"d":"9.48E-06"},{"v":0.000171334,"d":"1.71E-04"},{"v":6.66e-05,"d":"6.66E-05"},"MAPK8/TP53/MAP2K6/CREB1/PRKAA1/EGFR",6,{"v":11.86652542,"d":"11.87"}]
["GO-BP","GO:0043536","positive regulation of blood vessel endothelial cell migration",{"v":9.76e-06,"d":"9.76E-06"},{"v":0.00017374,"d":"1.74E-04"},{"v":6.75e-05,"d":"6.75E-05"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":29.54113924,"d":"29.54"}]
["GO-BP","GO:0071260","cellular response to mechanical stimulus",{"v":9.76e-06,"d":"9.76E-06"},{"v":0.00017374,"d":"1.74E-04"},{"v":6.75e-05,"d":"6.75E-05"},"MAPK8/PTPN11/AKT1/EGFR",4,{"v":29.54113924,"d":"29.54"}]
["GO-BP","GO:0016241","regulation of macroautophagy",{"v":1e-05,"d":"1.00E-05"},{"v":0.000176383,"d":"1.76E-04"},{"v":6.85e-05,"d":"6.85E-05"},"MAPK8/TP53/TBK1/PRKAA1/AKT1",5,{"v":17.05957602,"d":"17.06"}]
["GO-BP","GO:0044843","cell cycle G1/S phase transition",{"v":1e-05,"d":"1.00E-05"},{"v":0.000176383,"d":"1.76E-04"},{"v":6.85e-05,"d":"6.85E-05"},"PTPN6/TP53/ATM/EIF4EBP1/AKT1/EGFR",6,{"v":11.74706376,"d":"11.75"}]
["GO-BP","GO:0014855","striated muscle cell proliferation",{"v":1.08e-05,"d":"1.08E-05"},{"v":0.000187897,"d":"1.88E-04"},{"v":7.3e-05,"d":"7.30E-05"},"MAPK14/MAPK1/STAT3/JAK2",4,{"v":28.8117284,"d":"28.81"}]
["GO-BP","GO:2001252","positive regulation of chromosome organization",{"v":1.09e-05,"d":"1.09E-05"},{"v":0.000188729,"d":"1.89E-04"},{"v":7.33e-05,"d":"7.33E-05"},"TP53/SMAD4/RPS6KA4/MAPK1/ATM",5,{"v":16.7654454,"d":"16.77"}]
["GO-BP","GO:0042110","T cell activation",{"v":1.1e-05,"d":"1.10E-05"},{"v":0.000189031,"d":"1.89E-04"},{"v":7.34e-05,"d":"7.34E-05"},"PTPN6/TP53/PTPN11/STAT3/ZAP70/STAT6/AKT1",7,{"v":8.801858836,"d":"8.80"}]
["GO-BP","GO:0045088","regulation of innate immune response",{"v":1.15e-05,"d":"1.15E-05"},{"v":0.000195013,"d":"1.95E-04"},{"v":7.58e-05,"d":"7.58E-05"},"PTPN6/RBM14/PTPN11/JAK2/TBK1/PSMD9",6,{"v":11.47745902,"d":"11.48"}]
["GO-BP","GO:0090316","positive regulation of intracellular protein transport",{"v":1.15e-05,"d":"1.15E-05"},{"v":0.000195013,"d":"1.95E-04"},{"v":7.58e-05,"d":"7.58E-05"},"MAPK14/MAPK8/TP53/MAPK1/PRKAA1",5,{"v":16.57492898,"d":"16.57"}]
["GO-BP","GO:0002360","T cell lineage commitment",{"v":1.16e-05,"d":"1.16E-05"},{"v":0.000195013,"d":"1.95E-04"},{"v":7.58e-05,"d":"7.58E-05"},"TP53/STAT3/STAT6",3,{"v":67.31971154,"d":"67.32"}]
["GO-BP","GO:0009895","negative regulation of catabolic process",{"v":1.21e-05,"d":"1.21E-05"},{"v":0.000202798,"d":"2.03E-04"},{"v":7.88e-05,"d":"7.88E-05"},"MAPK14/TP53/STAT3/PRKAA1/AKT1/EGFR",6,{"v":11.36566558,"d":"11.37"}]
["GO-BP","GO:1903706","regulation of hemopoiesis",{"v":1.28e-05,"d":"1.28E-05"},{"v":0.000212099,"d":"2.12E-04"},{"v":8.24e-05,"d":"8.24E-05"},"PTPN6/MAPK14/STAT3/CREB1/ZAP70/NFKBIA/PSMD9",7,{"v":8.598026316,"d":"8.60"}]
["GO-BP","GO:1901796","regulation of signal transduction by p53 class mediator",{"v":1.28e-05,"d":"1.28E-05"},{"v":0.000212099,"d":"2.12E-04"},{"v":8.24e-05,"d":"8.24E-05"},"MAPK14/TP53/ATM/PRKAA1/AKT1",5,{"v":16.20659722,"d":"16.21"}]
["GO-BP","GO:0034612","response to tumor necrosis factor",{"v":1.3e-05,"d":"1.30E-05"},{"v":0.000213903,"d":"2.14E-04"},{"v":8.31e-05,"d":"8.31E-05"},"MAPK14/MAPK1/JAK2/NFKBIA/AKT1/PSMD9",6,{"v":11.21995192,"d":"11.22"}]
["GO-BP","GO:0048015","phosphatidylinositol-mediated signaling",{"v":1.32e-05,"d":"1.32E-05"},{"v":0.000215013,"d":"2.15E-04"},{"v":8.35e-05,"d":"8.35E-05"},"PTPN6/MAPK1/JAK2/AKT1/EGFR",5,{"v":16.11705801,"d":"16.12"}]
["GO-BP","GO:0070371","ERK1 and ERK2 cascade",{"v":1.43e-05,"d":"1.43E-05"},{"v":0.000224466,"d":"2.24E-04"},{"v":8.72e-05,"d":"8.72E-05"},"PTPN6/MAP2K1/SMAD4/PTPN11/MAPK1/EGFR",6,{"v":11.04298107,"d":"11.04"}]
["GO-BP","GO:0048017","inositol lipid-mediated signaling",{"v":1.43e-05,"d":"1.43E-05"},{"v":0.000224466,"d":"2.24E-04"},{"v":8.72e-05,"d":"8.72E-05"},"PTPN6/MAPK1/JAK2/AKT1/EGFR",5,{"v":15.85427989,"d":"15.85"}]
["GO-BP","GO:2000045","regulation of G1/S transition of mitotic cell cycle",{"v":1.43e-05,"d":"1.43E-05"},{"v":0.000224466,"d":"2.24E-04"},{"v":8.72e-05,"d":"8.72E-05"},"PTPN6/TP53/ATM/AKT1/EGFR",5,{"v":15.85427989,"d":"15.85"}]
["GO-BP","GO:0001892","embryonic placenta development",{"v":1.43e-05,"d":"1.43E-05"},{"v":0.000224466,"d":"2.24E-04"},{"v":8.72e-05,"d":"8.72E-05"},"MAP2K1/MAPK1/AKT1/EGFR",4,{"v":26.82471264,"d":"26.82"}]
["GO-BP","GO:0045844","positive regulation of striated muscle tissue development",{"v":1.43e-05,"d":"1.43E-05"},{"v":0.000224466,"d":"2.24E-04"},{"v":8.72e-05,"d":"8.72E-05"},"MAPK14/MAPK1/CREB1/PRKAA1",4,{"v":26.82471264,"d":"26.82"}]
["GO-BP","GO:0048636","positive regulation of muscle organ development",{"v":1.43e-05,"d":"1.43E-05"},{"v":0.000224466,"d":"2.24E-04"},{"v":8.72e-05,"d":"8.72E-05"},"MAPK14/MAPK1/CREB1/PRKAA1",4,{"v":26.82471264,"d":"26.82"}]
["GO-BP","GO:1902275","regulation of chromatin organization",{"v":1.47e-05,"d":"1.47E-05"},{"v":0.000228523,"d":"2.29E-04"},{"v":8.88e-05,"d":"8.88E-05"},"MAPK8/TP53/SMAD4/RPS6KA4/ATM",5,{"v":15.76858108,"d":"15.77"}]
["GO-BP","GO:1901863","positive regulation of muscle tissue development",{"v":1.5e-05,"d":"1.50E-05"},{"v":0.000231955,"d":"2.32E-04"},{"v":9.01e-05,"d":"9.01E-05"},"MAPK14/MAPK1/CREB1/PRKAA1",4,{"v":26.51988636,"d":"26.52"}]
["GO-BP","GO:0031058","positive regulation of histone modification",{"v":1.64e-05,"d":"1.64E-05"},{"v":0.000251992,"d":"2.52E-04"},{"v":9.79e-05,"d":"9.79E-05"},"TP53/SMAD4/RPS6KA4/ATM",4,{"v":25.93055556,"d":"25.93"}]
["GO-BP","GO:0046677","response to antibiotic",{"v":1.7e-05,"d":"1.70E-05"},{"v":0.000260085,"d":"2.60E-04"},{"v":0.000101031,"d":"1.01E-04"},"TP53/STAT3/JAK2/STAT6/EIF4EBP1/PRKAA1",6,{"v":10.70527523,"d":"10.71"}]
["GO-BP","GO:0051054","positive regulation of DNA metabolic process",{"v":1.71e-05,"d":"1.71E-05"},{"v":0.000260085,"d":"2.60E-04"},{"v":0.000101031,"d":"1.01E-04"},"MAPK1/ATM/STAT6/AKT1/EGFR",5,{"v":15.27323298,"d":"15.27"}]
["GO-BP","GO:0032496","response to lipopolysaccharide",{"v":1.79e-05,"d":"1.79E-05"},{"v":0.000270697,"d":"2.71E-04"},{"v":0.000105154,"d":"1.05E-04"},"MAPK14/MAPK8/MAPK1/JAK2/NFKBIA/AKT1",6,{"v":10.60795455,"d":"10.61"}]
["GO-BP","GO:0006476","protein deacetylation",{"v":1.86e-05,"d":"1.86E-05"},{"v":0.000278319,"d":"2.78E-04"},{"v":0.000108115,"d":"1.08E-04"},"MAPK8/TP53/RBM14/PRKAA1",4,{"v":25.09408602,"d":"25.09"}]
["GO-BP","GO:1901655","cellular response to ketone",{"v":1.86e-05,"d":"1.86E-05"},{"v":0.000278319,"d":"2.78E-04"},{"v":0.000108115,"d":"1.08E-04"},"EIF4EBP1/PRKAA1/AKT1/EGFR",4,{"v":25.09408602,"d":"25.09"}]
["GO-BP","GO:0060337","type I interferon signaling pathway",{"v":2.03e-05,"d":"2.03E-05"},{"v":0.000299156,"d":"2.99E-04"},{"v":0.000116209,"d":"1.16E-04"},"PTPN6/PTPN11/TYK2/TBK1",4,{"v":24.56578947,"d":"24.57"}]
["GO-BP","GO:0071357","cellular response to type I interferon",{"v":2.03e-05,"d":"2.03E-05"},{"v":0.000299156,"d":"2.99E-04"},{"v":0.000116209,"d":"1.16E-04"},"PTPN6/PTPN11/TYK2/TBK1",4,{"v":24.56578947,"d":"24.57"}]
["GO-BP","GO:0007179","transforming growth factor beta receptor signaling pathway",{"v":2.08e-05,"d":"2.08E-05"},{"v":0.00030573,"d":"3.06E-04"},{"v":0.000118763,"d":"1.19E-04"},"TP53/SMAD4/SMAD5/CREB1/SMAD2",5,{"v":14.65923367,"d":"14.66"}]
["GO-BP","GO:0033044","regulation of chromosome organization",{"v":2.19e-05,"d":"2.19E-05"},{"v":0.000317884,"d":"3.18E-04"},{"v":0.000123484,"d":"1.23E-04"},"MAPK8/TP53/SMAD4/RPS6KA4/MAPK1/ATM",6,{"v":10.23574561,"d":"10.24"}]
["GO-BP","GO:0060674","placenta blood vessel development",{"v":2.19e-05,"d":"2.19E-05"},{"v":0.000317884,"d":"3.18E-04"},{"v":0.000123484,"d":"1.23E-04"},"MAP2K1/MAPK1/AKT1",3,{"v":54.69726563,"d":"54.70"}]
["GO-BP","GO:0002237","response to molecule of bacterial origin",{"v":2.23e-05,"d":"2.23E-05"},{"v":0.000320984,"d":"3.21E-04"},{"v":0.000124688,"d":"1.25E-04"},"MAPK14/MAPK8/MAPK1/JAK2/NFKBIA/AKT1",6,{"v":10.20590379,"d":"10.21"}]
["GO-BP","GO:1902806","regulation of cell cycle G1/S phase transition",{"v":2.24e-05,"d":"2.24E-05"},{"v":0.000320984,"d":"3.21E-04"},{"v":0.000124688,"d":"1.25E-04"},"PTPN6/TP53/ATM/AKT1/EGFR",5,{"v":14.44152228,"d":"14.44"}]
["GO-BP","GO:0035265","organ growth",{"v":2.35e-05,"d":"2.35E-05"},{"v":0.00033462,"d":"3.35E-04"},{"v":0.000129985,"d":"1.30E-04"},"MAPK14/PTPN11/MAPK1/SMAD2/AKT1",5,{"v":14.29993873,"d":"14.30"}]
["GO-BP","GO:0048638","regulation of developmental growth",{"v":2.38e-05,"d":"2.38E-05"},{"v":0.000335607,"d":"3.36E-04"},{"v":0.000130369,"d":"1.30E-04"},"MAPK14/MAPK1/STAT3/CREB1/STAT5A/AKT1",6,{"v":10.08825648,"d":"10.09"}]
["GO-BP","GO:0034340","response to type I interferon",{"v":2.39e-05,"d":"2.39E-05"},{"v":0.000335607,"d":"3.36E-04"},{"v":0.000130369,"d":"1.30E-04"},"PTPN6/PTPN11/TYK2/TBK1",4,{"v":23.57323232,"d":"23.57"}]
["GO-BP","GO:0071222","cellular response to lipopolysaccharide",{"v":2.4e-05,"d":"2.40E-05"},{"v":0.000335607,"d":"3.36E-04"},{"v":0.000130369,"d":"1.30E-04"},"MAPK14/MAPK8/MAPK1/NFKBIA/AKT1",5,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:2000758","positive regulation of peptidyl-lysine acetylation",{"v":2.41e-05,"d":"2.41E-05"},{"v":0.000335607,"d":"3.36E-04"},{"v":0.000130369,"d":"1.30E-04"},"SMAD4/RPS6KA4/PRKAA1",3,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0055024","regulation of cardiac muscle tissue development",{"v":2.48e-05,"d":"2.48E-05"},{"v":0.000343888,"d":"3.44E-04"},{"v":0.000133585,"d":"1.34E-04"},"MAPK14/SMAD4/MAPK1/CREB1",4,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:0071456","cellular response to hypoxia",{"v":2.52e-05,"d":"2.52E-05"},{"v":0.000347017,"d":"3.47E-04"},{"v":0.000134801,"d":"1.35E-04"},"TP53/EIF4EBP1/PRKAA1/AKT1/PSMD9",5,{"v":14.09269324,"d":"14.09"}]
["GO-BP","GO:0051052","regulation of DNA metabolic process",{"v":2.54e-05,"d":"2.54E-05"},{"v":0.000347438,"d":"3.47E-04"},{"v":0.000134964,"d":"1.35E-04"},"TP53/MAPK1/ATM/STAT6/AKT1/EGFR",6,{"v":9.973290598,"d":"9.97"}]
["GO-BP","GO:0007623","circadian rhythm",{"v":2.58e-05,"d":"2.58E-05"},{"v":0.000351254,"d":"3.51E-04"},{"v":0.000136447,"d":"1.36E-04"},"MAPK8/TP53/CREB1/PRKAA1/EGFR",5,{"v":14.0249399,"d":"14.02"}]
["GO-BP","GO:0030098","lymphocyte differentiation",{"v":2.62e-05,"d":"2.62E-05"},{"v":0.000353821,"d":"3.54E-04"},{"v":0.000137444,"d":"1.37E-04"},"PTPN6/TP53/STAT3/ATM/ZAP70/STAT6",6,{"v":9.916784703,"d":"9.92"}]
["GO-BP","GO:0071229","cellular response to acid chemical",{"v":2.64e-05,"d":"2.64E-05"},{"v":0.000353821,"d":"3.54E-04"},{"v":0.000137444,"d":"1.37E-04"},"ATM/CREB1/PRKAA1/AKT1/EGFR",5,{"v":13.95783493,"d":"13.96"}]
["GO-BP","GO:0043368","positive T cell selection",{"v":2.64e-05,"d":"2.64E-05"},{"v":0.000353821,"d":"3.54E-04"},{"v":0.000137444,"d":"1.37E-04"},"STAT3/ZAP70/STAT6",3,{"v":51.47977941,"d":"51.48"}]
["GO-BP","GO:0035601","protein deacylation",{"v":2.79e-05,"d":"2.79E-05"},{"v":0.000369908,"d":"3.70E-04"},{"v":0.000143693,"d":"1.44E-04"},"MAPK8/TP53/RBM14/PRKAA1",4,{"v":22.65776699,"d":"22.66"}]
["GO-BP","GO:1905269","positive regulation of chromatin organization",{"v":2.79e-05,"d":"2.79E-05"},{"v":0.000369908,"d":"3.70E-04"},{"v":0.000143693,"d":"1.44E-04"},"TP53/SMAD4/RPS6KA4/ATM",4,{"v":22.65776699,"d":"22.66"}]
["GO-BP","GO:0071219","cellular response to molecule of bacterial origin",{"v":2.82e-05,"d":"2.82E-05"},{"v":0.000372626,"d":"3.73E-04"},{"v":0.000144749,"d":"1.45E-04"},"MAPK14/MAPK8/MAPK1/NFKBIA/AKT1",5,{"v":13.7603184,"d":"13.76"}]
["GO-BP","GO:0060338","regulation of type I interferon-mediated signaling pathway",{"v":2.88e-05,"d":"2.88E-05"},{"v":0.000376238,"d":"3.76E-04"},{"v":0.000146152,"d":"1.46E-04"},"PTPN6/PTPN11/TBK1",3,{"v":50.00892857,"d":"50.01"}]
["GO-BP","GO:0046822","regulation of nucleocytoplasmic transport",{"v":2.9e-05,"d":"2.90E-05"},{"v":0.000376238,"d":"3.76E-04"},{"v":0.000146152,"d":"1.46E-04"},"MAPK14/TP53/PTPN11/MAPK1",4,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:0098732","macromolecule deacylation",{"v":2.9e-05,"d":"2.90E-05"},{"v":0.000376238,"d":"3.76E-04"},{"v":0.000146152,"d":"1.46E-04"},"MAPK8/TP53/RBM14/PRKAA1",4,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:0008593","regulation of Notch signaling pathway",{"v":3.01e-05,"d":"3.01E-05"},{"v":0.000388645,"d":"3.89E-04"},{"v":0.000150972,"d":"1.51E-04"},"STAT3/NFKBIA/AKT1/EGFR",4,{"v":22.22619048,"d":"22.23"}]
["GO-BP","GO:0036294","cellular response to decreased oxygen levels",{"v":3.16e-05,"d":"3.16E-05"},{"v":0.000405888,"d":"4.06E-04"},{"v":0.00015767,"d":"1.58E-04"},"TP53/EIF4EBP1/PRKAA1/AKT1/PSMD9",5,{"v":13.44326037,"d":"13.44"}]
["GO-BP","GO:0046326","positive regulation of glucose import",{"v":3.7e-05,"d":"3.70E-05"},{"v":0.000473569,"d":"4.74E-04"},{"v":0.000183961,"d":"1.84E-04"},"MAPK14/PTPN11/AKT1",3,{"v":46.06085526,"d":"46.06"}]
["GO-BP","GO:0060964","regulation of gene silencing by miRNA",{"v":4.01e-05,"d":"4.01E-05"},{"v":0.000510549,"d":"5.11E-04"},{"v":0.000198326,"d":"1.98E-04"},"TP53/MAP2K1/STAT3/EGFR",4,{"v":20.65265487,"d":"20.65"}]
["GO-BP","GO:0032388","positive regulation of intracellular transport",{"v":4.08e-05,"d":"4.08E-05"},{"v":0.000516873,"d":"5.17E-04"},{"v":0.000200782,"d":"2.01E-04"},"MAPK14/MAPK8/TP53/MAPK1/PRKAA1",5,{"v":12.73881004,"d":"12.74"}]
["GO-BP","GO:0030218","erythrocyte differentiation",{"v":4.15e-05,"d":"4.15E-05"},{"v":0.000520513,"d":"5.21E-04"},{"v":0.000202196,"d":"2.02E-04"},"MAPK14/SMAD5/STAT3/JAK2",4,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0042752","regulation of circadian rhythm",{"v":4.15e-05,"d":"4.15E-05"},{"v":0.000520513,"d":"5.21E-04"},{"v":0.000202196,"d":"2.02E-04"},"MAPK8/TP53/CREB1/PRKAA1",4,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0031349","positive regulation of defense response",{"v":4.19e-05,"d":"4.19E-05"},{"v":0.000522906,"d":"5.23E-04"},{"v":0.000203126,"d":"2.03E-04"},"RBM14/JAK2/TBK1/NFKBIA/PSMD9/EGFR",6,{"v":9.116210938,"d":"9.12"}]
["GO-BP","GO:0060440","trachea formation",{"v":4.25e-05,"d":"4.25E-05"},{"v":0.000524622,"d":"5.25E-04"},{"v":0.000203793,"d":"2.04E-04"},"MAP2K1/MAPK1",2,{"v":194.4791667,"d":"194.48"}]
["GO-BP","GO:0070141","response to UV-A",{"v":4.25e-05,"d":"4.25E-05"},{"v":0.000524622,"d":"5.25E-04"},{"v":0.000203793,"d":"2.04E-04"},"AKT1/EGFR",2,{"v":194.4791667,"d":"194.48"}]
["GO-BP","GO:0097305","response to alcohol",{"v":4.44e-05,"d":"4.44E-05"},{"v":0.000543534,"d":"5.44E-04"},{"v":0.000211139,"d":"2.11E-04"},"STAT3/EIF4EBP1/PRKAA1/SMAD2/AKT1",5,{"v":12.52011803,"d":"12.52"}]
["GO-BP","GO:0007569","cell aging",{"v":4.45e-05,"d":"4.45E-05"},{"v":0.000543534,"d":"5.44E-04"},{"v":0.000211139,"d":"2.11E-04"},"MAPK14/TP53/MAP2K1/ATM",4,{"v":20.11853448,"d":"20.12"}]
["GO-BP","GO:0045787","positive regulation of cell cycle",{"v":4.51e-05,"d":"4.51E-05"},{"v":0.000547861,"d":"5.48E-04"},{"v":0.00021282,"d":"2.13E-04"},"TP53/PTPN11/ATM/EIF4EBP1/AKT1/EGFR",6,{"v":8.99903599,"d":"9.00"}]
["GO-BP","GO:0071453","cellular response to oxygen levels",{"v":4.53e-05,"d":"4.53E-05"},{"v":0.000547861,"d":"5.48E-04"},{"v":0.00021282,"d":"2.13E-04"},"TP53/EIF4EBP1/PRKAA1/AKT1/PSMD9",5,{"v":12.46661325,"d":"12.47"}]
["GO-BP","GO:0060147","regulation of posttranscriptional gene silencing",{"v":4.6e-05,"d":"4.60E-05"},{"v":0.00055129,"d":"5.51E-04"},{"v":0.000214152,"d":"2.14E-04"},"TP53/MAP2K1/STAT3/EGFR",4,{"v":19.9465812,"d":"19.95"}]
["GO-BP","GO:0060966","regulation of gene silencing by RNA",{"v":4.6e-05,"d":"4.60E-05"},{"v":0.00055129,"d":"5.51E-04"},{"v":0.000214152,"d":"2.14E-04"},"TP53/MAP2K1/STAT3/EGFR",4,{"v":19.9465812,"d":"19.95"}]
["GO-BP","GO:0007050","cell cycle arrest",{"v":4.81e-05,"d":"4.81E-05"},{"v":0.00057101,"d":"5.71E-04"},{"v":0.000221812,"d":"2.22E-04"},"TP53/MAP2K1/MAP2K6/ATM/PRKAA1",5,{"v":12.30880802,"d":"12.31"}]
["GO-BP","GO:0031669","cellular response to nutrient levels",{"v":4.81e-05,"d":"4.81E-05"},{"v":0.00057101,"d":"5.71E-04"},{"v":0.000221812,"d":"2.22E-04"},"MAPK8/TP53/MAPK1/EIF2S1/PRKAA1",5,{"v":12.30880802,"d":"12.31"}]
["GO-BP","GO:0002831","regulation of response to biotic stimulus",{"v":5.27e-05,"d":"5.27E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"PTPN6/RBM14/PTPN11/JAK2/TBK1/PSMD9",6,{"v":8.7515625,"d":"8.75"}]
["GO-BP","GO:0008631","intrinsic apoptotic signaling pathway in response to oxidative stress",{"v":5.39e-05,"d":"5.39E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"HSPB1/JAK2/AKT1",3,{"v":40.70494186,"d":"40.70"}]
["GO-BP","GO:0034198","cellular response to amino acid starvation",{"v":5.39e-05,"d":"5.39E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"MAPK8/MAPK1/EIF2S1",3,{"v":40.70494186,"d":"40.70"}]
["GO-BP","GO:0045746","negative regulation of Notch signaling pathway",{"v":5.39e-05,"d":"5.39E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"NFKBIA/AKT1/EGFR",3,{"v":40.70494186,"d":"40.70"}]
["GO-BP","GO:0071364","cellular response to epidermal growth factor stimulus",{"v":5.39e-05,"d":"5.39E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"PTPN11/AKT1/EGFR",3,{"v":40.70494186,"d":"40.70"}]
["GO-BP","GO:1901985","positive regulation of protein acetylation",{"v":5.39e-05,"d":"5.39E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"SMAD4/RPS6KA4/PRKAA1",3,{"v":40.70494186,"d":"40.70"}]
["GO-BP","GO:0022407","regulation of cell-cell adhesion",{"v":5.41e-05,"d":"5.41E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"PTPN6/MAPK14/PTPN11/JAK2/ZAP70/AKT1",6,{"v":8.708022388,"d":"8.71"}]
["GO-BP","GO:0034101","erythrocyte homeostasis",{"v":5.42e-05,"d":"5.42E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"MAPK14/SMAD5/STAT3/JAK2",4,{"v":19.12909836,"d":"19.13"}]
["GO-BP","GO:1905477","positive regulation of protein localization to membrane",{"v":5.42e-05,"d":"5.42E-05"},{"v":0.000616624,"d":"6.17E-04"},{"v":0.000239532,"d":"2.40E-04"},"MAPK8/TP53/AKT1/EGFR",4,{"v":19.12909836,"d":"19.13"}]
["GO-BP","GO:0045785","positive regulation of cell adhesion",{"v":5.49e-05,"d":"5.49E-05"},{"v":0.000621934,"d":"6.22E-04"},{"v":0.000241594,"d":"2.42E-04"},"PTPN6/PTPN11/ATM/JAK2/ZAP70/AKT1",6,{"v":8.686414392,"d":"8.69"}]
["GO-BP","GO:0014066","regulation of phosphatidylinositol 3-kinase signaling",{"v":5.77e-05,"d":"5.77E-05"},{"v":0.000645598,"d":"6.46E-04"},{"v":0.000250786,"d":"2.51E-04"},"PTPN6/MAPK1/JAK2/EGFR",4,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:0010828","positive regulation of glucose transmembrane transport",{"v":5.77e-05,"d":"5.77E-05"},{"v":0.000645598,"d":"6.46E-04"},{"v":0.000250786,"d":"2.51E-04"},"MAPK14/PTPN11/AKT1",3,{"v":39.77982955,"d":"39.78"}]
["GO-BP","GO:0090311","regulation of protein deacetylation",{"v":5.77e-05,"d":"5.77E-05"},{"v":0.000645598,"d":"6.46E-04"},{"v":0.000250786,"d":"2.51E-04"},"MAPK8/TP53/PRKAA1",3,{"v":39.77982955,"d":"39.78"}]
["GO-BP","GO:0036302","atrioventricular canal development",{"v":5.94e-05,"d":"5.94E-05"},{"v":0.000656926,"d":"6.57E-04"},{"v":0.000255187,"d":"2.55E-04"},"SMAD4/PTPN11",2,{"v":166.6964286,"d":"166.70"}]
["GO-BP","GO:0031929","TOR signaling",{"v":5.96e-05,"d":"5.96E-05"},{"v":0.000656926,"d":"6.57E-04"},{"v":0.000255187,"d":"2.55E-04"},"ATM/EIF4EBP1/PRKAA1/AKT1",4,18.67]
["GO-BP","GO:0032368","regulation of lipid transport",{"v":5.96e-05,"d":"5.96E-05"},{"v":0.000656926,"d":"6.57E-04"},{"v":0.000255187,"d":"2.55E-04"},"PTPN11/MAP2K6/NFKBIA/AKT1",4,18.67]
["GO-BP","GO:0071560","cellular response to transforming growth factor beta stimulus",{"v":6.08e-05,"d":"6.08E-05"},{"v":0.00066786,"d":"6.68E-04"},{"v":0.000259434,"d":"2.59E-04"},"TP53/SMAD4/SMAD5/CREB1/SMAD2",5,{"v":11.71561245,"d":"11.72"}]
["GO-BP","GO:0048538","thymus development",{"v":6.18e-05,"d":"6.18E-05"},{"v":0.000674721,"d":"6.75E-04"},{"v":0.0002621,"d":"2.62E-04"},"MAP2K1/MAPK1/ATM",3,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0030072","peptide hormone secretion",{"v":6.2e-05,"d":"6.20E-05"},{"v":0.000674721,"d":"6.75E-04"},{"v":0.0002621,"d":"2.62E-04"},"PTPN11/JAK2/SMAD2/PSMD9/EGFR",5,{"v":11.66875,"d":"11.67"}]
["GO-BP","GO:0010595","positive regulation of endothelial cell migration",{"v":6.53e-05,"d":"6.53E-05"},{"v":0.000707997,"d":"7.08E-04"},{"v":0.000275026,"d":"2.75E-04"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:0060711","labyrinthine layer development",{"v":6.6e-05,"d":"6.60E-05"},{"v":0.000712683,"d":"7.13E-04"},{"v":0.000276846,"d":"2.77E-04"},"MAP2K1/MAPK1/AKT1",3,{"v":38.05027174,"d":"38.05"}]
["GO-BP","GO:0071559","response to transforming growth factor beta",{"v":6.81e-05,"d":"6.81E-05"},{"v":0.000731462,"d":"7.31E-04"},{"v":0.000284141,"d":"2.84E-04"},"TP53/SMAD4/SMAD5/CREB1/SMAD2",5,{"v":11.43995098,"d":"11.44"}]
["GO-BP","GO:0045058","T cell selection",{"v":7.05e-05,"d":"7.05E-05"},{"v":0.000749308,"d":"7.49E-04"},{"v":0.000291073,"d":"2.91E-04"},"STAT3/ZAP70/STAT6",3,{"v":37.24069149,"d":"37.24"}]
["GO-BP","GO:0061614","pri-miRNA transcription by RNA polymerase II",{"v":7.05e-05,"d":"7.05E-05"},{"v":0.000749308,"d":"7.49E-04"},{"v":0.000291073,"d":"2.91E-04"},"TP53/SMAD4/STAT3",3,{"v":37.24069149,"d":"37.24"}]
["GO-BP","GO:0048863","stem cell differentiation",{"v":7.06e-05,"d":"7.06E-05"},{"v":0.000749308,"d":"7.49E-04"},{"v":0.000291073,"d":"2.91E-04"},"TP53/SMAD4/MAPK1/STAT3/PSMD9",5,{"v":11.35092412,"d":"11.35"}]
["GO-BP","GO:0060324","face development",{"v":7.51e-05,"d":"7.51E-05"},{"v":0.000792974,"d":"7.93E-04"},{"v":0.000308036,"d":"3.08E-04"},"MAP2K1/PTPN11/MAPK1",3,{"v":36.46484375,"d":"36.46"}]
["GO-BP","GO:0048568","embryonic organ development",{"v":7.66e-05,"d":"7.66E-05"},{"v":0.000805608,"d":"8.06E-04"},{"v":0.000312943,"d":"3.13E-04"},"TP53/MAP2K1/MAPK1/SMAD2/AKT1/EGFR",6,{"v":8.179030374,"d":"8.18"}]
["GO-BP","GO:0006975","DNA damage induced protein phosphorylation",{"v":7.92e-05,"d":"7.92E-05"},{"v":0.000822475,"d":"8.22E-04"},{"v":0.000319496,"d":"3.19E-04"},"MAP2K6/ATM",2,{"v":145.859375,"d":"145.86"}]
["GO-BP","GO:0033129","positive regulation of histone phosphorylation",{"v":7.92e-05,"d":"7.92E-05"},{"v":0.000822475,"d":"8.22E-04"},{"v":0.000319496,"d":"3.19E-04"},"RPS6KA4/ATM",2,{"v":145.859375,"d":"145.86"}]
["GO-BP","GO:0090400","stress-induced premature senescence",{"v":7.92e-05,"d":"7.92E-05"},{"v":0.000822475,"d":"8.22E-04"},{"v":0.000319496,"d":"3.19E-04"},"MAPK14/TP53",2,{"v":145.859375,"d":"145.86"}]
["GO-BP","GO:0035690","cellular response to drug",{"v":8.17e-05,"d":"8.17E-05"},{"v":0.000844657,"d":"8.45E-04"},{"v":0.000328112,"d":"3.28E-04"},"TP53/MAPK1/STAT6/EIF4EBP1/PRKAA1/EGFR",6,{"v":8.084584296,"d":"8.08"}]
["GO-BP","GO:0072331","signal transduction by p53 class mediator",{"v":8.46e-05,"d":"8.46E-05"},{"v":0.000869128,"d":"8.69E-04"},{"v":0.000337618,"d":"3.38E-04"},"MAPK14/TP53/ATM/PRKAA1/AKT1",5,{"v":10.92579588,"d":"10.93"}]
["GO-BP","GO:0002931","response to ischemia",{"v":8.49e-05,"d":"8.49E-05"},{"v":0.000869128,"d":"8.69E-04"},{"v":0.000337618,"d":"3.38E-04"},"TP53/MAP2K6/EIF4EBP1",3,{"v":35.00625,"d":"35.01"}]
["GO-BP","GO:0072655","establishment of protein localization to mitochondrion",{"v":8.51e-05,"d":"8.51E-05"},{"v":0.000869128,"d":"8.69E-04"},{"v":0.000337618,"d":"3.38E-04"},"MAPK8/TP53/PRKAA1/AKT1",4,{"v":17.03467153,"d":"17.03"}]
["GO-BP","GO:0031668","cellular response to extracellular stimulus",{"v":8.61e-05,"d":"8.61E-05"},{"v":0.000875983,"d":"8.76E-04"},{"v":0.000340281,"d":"3.40E-04"},"MAPK8/TP53/MAPK1/EIF2S1/PRKAA1",5,{"v":10.88502799,"d":"10.89"}]
["GO-BP","GO:0060249","anatomical structure homeostasis",{"v":8.81e-05,"d":"8.81E-05"},{"v":0.000892666,"d":"8.93E-04"},{"v":0.000346762,"d":"3.47E-04"},"HSPB1/PTPN11/MAPK1/ATM/PRKAA1/EGFR",6,{"v":7.974088838,"d":"7.97"}]
["GO-BP","GO:0033135","regulation of peptidyl-serine phosphorylation",{"v":9e-05,"d":"9.00E-05"},{"v":0.000904556,"d":"9.05E-04"},{"v":0.00035138,"d":"3.51E-04"},"TBK1/PRKAA1/AKT1/EGFR",4,{"v":16.78956835,"d":"16.79"}]
["GO-BP","GO:0060968","regulation of gene silencing",{"v":9e-05,"d":"9.00E-05"},{"v":0.000904556,"d":"9.05E-04"},{"v":0.00035138,"d":"3.51E-04"},"TP53/MAP2K1/STAT3/EGFR",4,{"v":16.78956835,"d":"16.79"}]
["GO-BP","GO:0046651","lymphocyte proliferation",{"v":9.23e-05,"d":"9.23E-05"},{"v":0.000924215,"d":"9.24E-04"},{"v":0.000359017,"d":"3.59E-04"},"PTPN6/TP53/ATM/ZAP70/TBK1",5,{"v":10.72495404,"d":"10.72"}]
["GO-BP","GO:1901990","regulation of mitotic cell cycle phase transition",{"v":9.37e-05,"d":"9.37E-05"},{"v":0.000934859,"d":"9.35E-04"},{"v":0.000363152,"d":"3.63E-04"},"PTPN6/TP53/ATM/AKT1/PSMD9/EGFR",6,{"v":7.884290541,"d":"7.88"}]
["GO-BP","GO:0008286","insulin receptor signaling pathway",{"v":9.51e-05,"d":"9.51E-05"},{"v":0.000940876,"d":"9.41E-04"},{"v":0.000365489,"d":"3.65E-04"},"PTPN11/EIF4EBP1/PRKAA1/AKT1",4,{"v":16.55141844,"d":"16.55"}]
["GO-BP","GO:0070585","protein localization to mitochondrion",{"v":9.51e-05,"d":"9.51E-05"},{"v":0.000940876,"d":"9.41E-04"},{"v":0.000365489,"d":"3.65E-04"},"MAPK8/TP53/PRKAA1/AKT1",4,{"v":16.55141844,"d":"16.55"}]
["GO-BP","GO:0032943","mononuclear cell proliferation",{"v":9.55e-05,"d":"9.55E-05"},{"v":0.000941516,"d":"9.42E-04"},{"v":0.000365738,"d":"3.66E-04"},"PTPN6/TP53/ATM/ZAP70/TBK1",5,{"v":10.64666971,"d":"10.65"}]
["GO-BP","GO:0038127","ERBB signaling pathway",{"v":9.77e-05,"d":"9.77E-05"},{"v":0.000959373,"d":"9.59E-04"},{"v":0.000372674,"d":"3.73E-04"},"PTPN11/MAPK1/AKT1/EGFR",4,{"v":16.43485915,"d":"16.43"}]
["GO-BP","GO:0000186","activation of MAPKK activity",{"v":0.000101082,"d":"1.01E-04"},{"v":0.000975079,"d":"9.75E-04"},{"v":0.000378775,"d":"3.79E-04"},"MAPK1/JAK2/EGFR",3,{"v":33.02476415,"d":"33.02"}]
["GO-BP","GO:0038113","interleukin-9-mediated signaling pathway",{"v":0.000101693,"d":"1.02E-04"},{"v":0.000975079,"d":"9.75E-04"},{"v":0.000378775,"d":"3.79E-04"},"STAT3/STAT5A",2,{"v":129.6527778,"d":"129.65"}]
["GO-BP","GO:0071355","cellular response to interleukin-9",{"v":0.000101693,"d":"1.02E-04"},{"v":0.000975079,"d":"9.75E-04"},{"v":0.000378775,"d":"3.79E-04"},"STAT3/STAT5A",2,{"v":129.6527778,"d":"129.65"}]
["GO-BP","GO:0097011","cellular response to granulocyte macrophage colony-stimulating factor stimulus",{"v":0.000101693,"d":"1.02E-04"},{"v":0.000975079,"d":"9.75E-04"},{"v":0.000378775,"d":"3.79E-04"},"MAPK1/AKT1",2,{"v":129.6527778,"d":"129.65"}]
["GO-BP","GO:0097012","response to granulocyte macrophage colony-stimulating factor",{"v":0.000101693,"d":"1.02E-04"},{"v":0.000975079,"d":"9.75E-04"},{"v":0.000378775,"d":"3.79E-04"},"MAPK1/AKT1",2,{"v":129.6527778,"d":"129.65"}]
["GO-BP","GO:0099527","postsynapse to nucleus signaling pathway",{"v":0.000101693,"d":"1.02E-04"},{"v":0.000975079,"d":"9.75E-04"},{"v":0.000378775,"d":"3.79E-04"},"STAT3/JAK2",2,{"v":129.6527778,"d":"129.65"}]
["GO-BP","GO:0030522","intracellular receptor signaling pathway",{"v":0.000102288,"d":"1.02E-04"},{"v":0.000977031,"d":"9.77E-04"},{"v":0.000379534,"d":"3.80E-04"},"RBM14/MAP2K6/STAT3/JAK2/NFKBIA",5,{"v":10.49348022,"d":"10.49"}]
["GO-BP","GO:0000077","DNA damage checkpoint",{"v":0.000105984,"d":"1.06E-04"},{"v":0.001008466,"d":"1.01E-03"},{"v":0.000391745,"d":"3.92E-04"},"MAPK14/TP53/PTPN11/ATM",4,{"v":16.09482759,"d":"16.09"}]
["GO-BP","GO:0016579","protein deubiquitination",{"v":0.000111221,"d":"1.11E-04"},{"v":0.001051285,"d":"1.05E-03"},{"v":0.000408378,"d":"4.08E-04"},"TP53/SMAD4/NFKBIA/SMAD2/PSMD9",5,{"v":10.30808304,"d":"10.31"}]
["GO-BP","GO:0002262","myeloid cell homeostasis",{"v":0.000111749,"d":"1.12E-04"},{"v":0.001051285,"d":"1.05E-03"},{"v":0.000408378,"d":"4.08E-04"},"MAPK14/SMAD5/STAT3/JAK2",4,{"v":15.87585034,"d":"15.88"}]
["GO-BP","GO:0010212","response to ionizing radiation",{"v":0.000111749,"d":"1.12E-04"},{"v":0.001051285,"d":"1.05E-03"},{"v":0.000408378,"d":"4.08E-04"},"MAPK14/TP53/ATM/PRKAA1",4,{"v":15.87585034,"d":"15.88"}]
["GO-BP","GO:0010332","response to gamma radiation",{"v":0.000119194,"d":"1.19E-04"},{"v":0.00111292,"d":"1.11E-03"},{"v":0.000432321,"d":"4.32E-04"},"TP53/ATM/PRKAA1",3,{"v":31.25558036,"d":"31.26"}]
["GO-BP","GO:0031295","T cell costimulation",{"v":0.000119194,"d":"1.19E-04"},{"v":0.00111292,"d":"1.11E-03"},{"v":0.000432321,"d":"4.32E-04"},"PTPN6/PTPN11/AKT1",3,{"v":31.25558036,"d":"31.26"}]
["GO-BP","GO:0097193","intrinsic apoptotic signaling pathway",{"v":0.00012272,"d":"1.23E-04"},{"v":0.00114157,"d":"1.14E-03"},{"v":0.00044345,"d":"4.43E-04"},"TP53/HSPB1/ATM/JAK2/AKT1",5,{"v":10.09407439,"d":"10.09"}]
["GO-BP","GO:0031294","lymphocyte costimulation",{"v":0.000125669,"d":"1.26E-04"},{"v":0.001160345,"d":"1.16E-03"},{"v":0.000450743,"d":"4.51E-04"},"PTPN6/PTPN11/AKT1",3,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:0071398","cellular response to fatty acid",{"v":0.000125669,"d":"1.26E-04"},{"v":0.001160345,"d":"1.16E-03"},{"v":0.000450743,"d":"4.51E-04"},"CREB1/PRKAA1/AKT1",3,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:0071104","response to interleukin-9",{"v":0.00012698,"d":"1.27E-04"},{"v":0.001168124,"d":"1.17E-03"},{"v":0.000453765,"d":"4.54E-04"},"STAT3/STAT5A",2,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0030168","platelet activation",{"v":0.000130413,"d":"1.30E-04"},{"v":0.001195293,"d":"1.20E-03"},{"v":0.000464319,"d":"4.64E-04"},"PTPN6/HSPB1/PTPN11/MAPK1",4,{"v":15.25326797,"d":"15.25"}]
["GO-BP","GO:0061900","glial cell activation",{"v":0.00013237,"d":"1.32E-04"},{"v":0.001204371,"d":"1.20E-03"},{"v":0.000467845,"d":"4.68E-04"},"ATM/JAK2/EGFR",3,{"v":30.17780172,"d":"30.18"}]
["GO-BP","GO:1903749","positive regulation of establishment of protein localization to mitochondrion",{"v":0.00013237,"d":"1.32E-04"},{"v":0.001204371,"d":"1.20E-03"},{"v":0.000467845,"d":"4.68E-04"},"MAPK8/TP53/PRKAA1",3,{"v":30.17780172,"d":"30.18"}]
["GO-BP","GO:0016236","macroautophagy",{"v":0.000135112,"d":"1.35E-04"},{"v":0.00122485,"d":"1.22E-03"},{"v":0.0004758,"d":"4.76E-04"},"MAPK8/TP53/TBK1/PRKAA1/AKT1",5,{"v":9.888771186,"d":"9.89"}]
["GO-BP","GO:2000756","regulation of peptidyl-lysine acetylation",{"v":0.000139299,"d":"1.39E-04"},{"v":0.001258231,"d":"1.26E-03"},{"v":0.000488768,"d":"4.89E-04"},"SMAD4/RPS6KA4/PRKAA1",3,{"v":29.66631356,"d":"29.67"}]
["GO-BP","GO:0043535","regulation of blood vessel endothelial cell migration",{"v":0.000140548,"d":"1.41E-04"},{"v":0.001260378,"d":"1.26E-03"},{"v":0.000489602,"d":"4.90E-04"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":14.9599359,"d":"14.96"}]
["GO-BP","GO:1905952","regulation of lipid localization",{"v":0.000140548,"d":"1.41E-04"},{"v":0.001260378,"d":"1.26E-03"},{"v":0.000489602,"d":"4.90E-04"},"PTPN11/MAP2K6/NFKBIA/AKT1",4,{"v":14.9599359,"d":"14.96"}]
["GO-BP","GO:0070661","leukocyte proliferation",{"v":0.000141657,"d":"1.42E-04"},{"v":0.001265775,"d":"1.27E-03"},{"v":0.000491698,"d":"4.92E-04"},"PTPN6/TP53/ATM/ZAP70/TBK1",5,{"v":9.789219799,"d":"9.79"}]
["GO-BP","GO:1901987","regulation of cell cycle phase transition",{"v":0.000143672,"d":"1.44E-04"},{"v":0.001268956,"d":"1.27E-03"},{"v":0.000492934,"d":"4.93E-04"},"PTPN6/TP53/ATM/AKT1/PSMD9/EGFR",6,{"v":7.29296875,"d":"7.29"}]
["GO-BP","GO:0070646","protein modification by small protein removal",{"v":0.000143892,"d":"1.44E-04"},{"v":0.001268956,"d":"1.27E-03"},{"v":0.000492934,"d":"4.93E-04"},"TP53/SMAD4/NFKBIA/SMAD2/PSMD9",5,{"v":9.756479933,"d":"9.76"}]
["GO-BP","GO:0031570","DNA integrity checkpoint",{"v":0.000144049,"d":"1.44E-04"},{"v":0.001268956,"d":"1.27E-03"},{"v":0.000492934,"d":"4.93E-04"},"MAPK14/TP53/PTPN11/ATM",4,{"v":14.86464968,"d":"14.86"}]
["GO-BP","GO:0043467","regulation of generation of precursor metabolites and energy",{"v":0.000144049,"d":"1.44E-04"},{"v":0.001268956,"d":"1.27E-03"},{"v":0.000492934,"d":"4.93E-04"},"TP53/STAT3/PRKAA1/AKT1",4,{"v":14.86464968,"d":"14.86"}]
["GO-BP","GO:0070372","regulation of ERK1 and ERK2 cascade",{"v":0.000146154,"d":"1.46E-04"},{"v":0.001281138,"d":"1.28E-03"},{"v":0.000497666,"d":"4.98E-04"},"PTPN6/MAP2K1/SMAD4/PTPN11/EGFR",5,{"v":9.723958333,"d":"9.72"}]
["GO-BP","GO:0046324","regulation of glucose import",{"v":0.00014646,"d":"1.46E-04"},{"v":0.001281138,"d":"1.28E-03"},{"v":0.000497666,"d":"4.98E-04"},"MAPK14/PTPN11/AKT1",3,{"v":29.171875,"d":"29.17"}]
["GO-BP","GO:0007259","receptor signaling pathway via JAK-STAT",{"v":0.000151241,"d":"1.51E-04"},{"v":0.001318338,"d":"1.32E-03"},{"v":0.000512117,"d":"5.12E-04"},"STAT3/JAK2/STAT6/STAT5A",4,{"v":14.67767296,"d":"14.68"}]
["GO-BP","GO:0051249","regulation of lymphocyte activation",{"v":0.000152019,"d":"1.52E-04"},{"v":0.001319093,"d":"1.32E-03"},{"v":0.00051241,"d":"5.12E-04"},"PTPN6/PTPN11/ATM/ZAP70/STAT6/AKT1",6,{"v":7.217783505,"d":"7.22"}]
["GO-BP","GO:1905953","negative regulation of lipid localization",{"v":0.000153856,"d":"1.54E-04"},{"v":0.001319093,"d":"1.32E-03"},{"v":0.00051241,"d":"5.12E-04"},"PTPN11/NFKBIA/AKT1",3,{"v":28.69364754,"d":"28.69"}]
["GO-BP","GO:0032680","regulation of tumor necrosis factor production",{"v":0.000154933,"d":"1.55E-04"},{"v":0.001319093,"d":"1.32E-03"},{"v":0.00051241,"d":"5.12E-04"},"PTPN6/HSPB1/PTPN11/JAK2",4,{"v":14.5859375,"d":"14.59"}]
["GO-BP","GO:0035404","histone-serine phosphorylation",{"v":0.000155032,"d":"1.55E-04"},{"v":0.001319093,"d":"1.32E-03"},{"v":0.00051241,"d":"5.12E-04"},"RPS6KA4/PRKAA1",2,{"v":106.0795455,"d":"106.08"}]
["GO-BP","GO:0045899","positive regulation of RNA polymerase II transcription preinitiation complex assembly",{"v":0.000155032,"d":"1.55E-04"},{"v":0.001319093,"d":"1.32E-03"},{"v":0.00051241,"d":"5.12E-04"},"TP53/CREB1",2,{"v":106.0795455,"d":"106.08"}]
["GO-BP","GO:0060439","trachea morphogenesis",{"v":0.000155032,"d":"1.55E-04"},{"v":0.001319093,"d":"1.32E-03"},{"v":0.00051241,"d":"5.12E-04"},"MAP2K1/MAPK1",2,{"v":106.0795455,"d":"106.08"}]
["GO-BP","GO:0070757","interleukin-35-mediated signaling pathway",{"v":0.000155032,"d":"1.55E-04"},{"v":0.001319093,"d":"1.32E-03"},{"v":0.00051241,"d":"5.12E-04"},"STAT3/JAK2",2,{"v":106.0795455,"d":"106.08"}]
["GO-BP","GO:0009880","embryonic pattern specification",{"v":0.000161491,"d":"1.61E-04"},{"v":0.001355549,"d":"1.36E-03"},{"v":0.000526571,"d":"5.27E-04"},"SMAD4/SMAD5/SMAD2",3,{"v":28.23084677,"d":"28.23"}]
["GO-BP","GO:0046824","positive regulation of nucleocytoplasmic transport",{"v":0.000161491,"d":"1.61E-04"},{"v":0.001355549,"d":"1.36E-03"},{"v":0.000526571,"d":"5.27E-04"},"MAPK14/TP53/MAPK1",3,{"v":28.23084677,"d":"28.23"}]
["GO-BP","GO:0051205","protein insertion into membrane",{"v":0.000161491,"d":"1.61E-04"},{"v":0.001355549,"d":"1.36E-03"},{"v":0.000526571,"d":"5.27E-04"},"MAPK8/TP53/EGFR",3,{"v":28.23084677,"d":"28.23"}]
["GO-BP","GO:0055025","positive regulation of cardiac muscle tissue development",{"v":0.000161491,"d":"1.61E-04"},{"v":0.001355549,"d":"1.36E-03"},{"v":0.000526571,"d":"5.27E-04"},"MAPK14/MAPK1/CREB1",3,{"v":28.23084677,"d":"28.23"}]
["GO-BP","GO:0032640","tumor necrosis factor production",{"v":0.000166401,"d":"1.66E-04"},{"v":0.001382796,"d":"1.38E-03"},{"v":0.000537155,"d":"5.37E-04"},"PTPN6/HSPB1/PTPN11/JAK2",4,{"v":14.31748466,"d":"14.32"}]
["GO-BP","GO:0045931","positive regulation of mitotic cell cycle",{"v":0.000166401,"d":"1.66E-04"},{"v":0.001382796,"d":"1.38E-03"},{"v":0.000537155,"d":"5.37E-04"},"PTPN11/EIF4EBP1/AKT1/EGFR",4,{"v":14.31748466,"d":"14.32"}]
["GO-BP","GO:1903555","regulation of tumor necrosis factor superfamily cytokine production",{"v":0.000166401,"d":"1.66E-04"},{"v":0.001382796,"d":"1.38E-03"},{"v":0.000537155,"d":"5.37E-04"},"PTPN6/HSPB1/PTPN11/JAK2",4,{"v":14.31748466,"d":"14.32"}]
["GO-BP","GO:0046622","positive regulation of organ growth",{"v":0.000169369,"d":"1.69E-04"},{"v":0.001402779,"d":"1.40E-03"},{"v":0.000544918,"d":"5.45E-04"},"MAPK14/MAPK1/AKT1",3,{"v":27.7827381,"d":"27.78"}]
["GO-BP","GO:0042113","B cell activation",{"v":0.000170307,"d":"1.70E-04"},{"v":0.001405875,"d":"1.41E-03"},{"v":0.000546121,"d":"5.46E-04"},"PTPN6/TP53/ATM/ZAP70/STAT6",5,{"v":9.410282258,"d":"9.41"}]
["GO-BP","GO:0045600","positive regulation of fat cell differentiation",{"v":0.000177492,"d":"1.77E-04"},{"v":0.001460354,"d":"1.46E-03"},{"v":0.000567283,"d":"5.67E-04"},"MAPK14/CREB1/AKT1",3,{"v":27.34863281,"d":"27.35"}]
["GO-BP","GO:0071706","tumor necrosis factor superfamily cytokine production",{"v":0.000186862,"d":"1.87E-04"},{"v":0.001532394,"d":"1.53E-03"},{"v":0.000595268,"d":"5.95E-04"},"PTPN6/HSPB1/PTPN11/JAK2",4,{"v":13.89136905,"d":"13.89"}]
["GO-BP","GO:0097696","receptor signaling pathway via STAT",{"v":0.000191163,"d":"1.91E-04"},{"v":0.001562522,"d":"1.56E-03"},{"v":0.000606971,"d":"6.07E-04"},"STAT3/JAK2/STAT6/STAT5A",4,{"v":13.8091716,"d":"13.81"}]
["GO-BP","GO:0040014","regulation of multicellular organism growth",{"v":0.000194488,"d":"1.94E-04"},{"v":0.001584506,"d":"1.58E-03"},{"v":0.000615511,"d":"6.16E-04"},"STAT3/CREB1/STAT5A",3,{"v":26.51988636,"d":"26.52"}]
["GO-BP","GO:0010634","positive regulation of epithelial cell migration",{"v":0.000199978,"d":"2.00E-04"},{"v":0.001623927,"d":"1.62E-03"},{"v":0.000630824,"d":"6.31E-04"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":13.64766082,"d":"13.65"}]
["GO-BP","GO:0001659","temperature homeostasis",{"v":0.000209083,"d":"2.09E-04"},{"v":0.001692353,"d":"1.69E-03"},{"v":0.000657405,"d":"6.57E-04"},"MAP2K6/STAT3/JAK2/STAT6",4,{"v":13.48988439,"d":"13.49"}]
["GO-BP","GO:0046323","glucose import",{"v":0.000212507,"d":"2.13E-04"},{"v":0.001714498,"d":"1.71E-03"},{"v":0.000666007,"d":"6.66E-04"},"MAPK14/PTPN11/AKT1",3,{"v":25.73988971,"d":"25.74"}]
["GO-BP","GO:0007183","SMAD protein complex assembly",{"v":0.000219393,"d":"2.19E-04"},{"v":0.001736338,"d":"1.74E-03"},{"v":0.000674491,"d":"6.74E-04"},"SMAD4/SMAD2",2,{"v":89.75961538,"d":"89.76"}]
["GO-BP","GO:0014842","regulation of skeletal muscle satellite cell proliferation",{"v":0.000219393,"d":"2.19E-04"},{"v":0.001736338,"d":"1.74E-03"},{"v":0.000674491,"d":"6.74E-04"},"STAT3/JAK2",2,{"v":89.75961538,"d":"89.76"}]
["GO-BP","GO:0033127","regulation of histone phosphorylation",{"v":0.000219393,"d":"2.19E-04"},{"v":0.001736338,"d":"1.74E-03"},{"v":0.000674491,"d":"6.74E-04"},"RPS6KA4/ATM",2,{"v":89.75961538,"d":"89.76"}]
["GO-BP","GO:0035723","interleukin-15-mediated signaling pathway",{"v":0.000219393,"d":"2.19E-04"},{"v":0.001736338,"d":"1.74E-03"},{"v":0.000674491,"d":"6.74E-04"},"STAT3/STAT5A",2,{"v":89.75961538,"d":"89.76"}]
["GO-BP","GO:0071350","cellular response to interleukin-15",{"v":0.000219393,"d":"2.19E-04"},{"v":0.001736338,"d":"1.74E-03"},{"v":0.000674491,"d":"6.74E-04"},"STAT3/STAT5A",2,{"v":89.75961538,"d":"89.76"}]
["GO-BP","GO:0090399","replicative senescence",{"v":0.000219393,"d":"2.19E-04"},{"v":0.001736338,"d":"1.74E-03"},{"v":0.000674491,"d":"6.74E-04"},"TP53/ATM",2,{"v":89.75961538,"d":"89.76"}]
["GO-BP","GO:0009408","response to heat",{"v":0.000223297,"d":"2.23E-04"},{"v":0.001761645,"d":"1.76E-03"},{"v":0.000684322,"d":"6.84E-04"},"MAPK1/EIF2S1/ATM/AKT1",4,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0001959","regulation of cytokine-mediated signaling pathway",{"v":0.000228186,"d":"2.28E-04"},{"v":0.001788895,"d":"1.79E-03"},{"v":0.000694907,"d":"6.95E-04"},"PTPN6/PTPN11/JAK2/TBK1",4,{"v":13.18502825,"d":"13.19"}]
["GO-BP","GO:0043488","regulation of mRNA stability",{"v":0.000228186,"d":"2.28E-04"},{"v":0.001788895,"d":"1.79E-03"},{"v":0.000694907,"d":"6.95E-04"},"MAPK14/HSPB1/AKT1/PSMD9",4,{"v":13.18502825,"d":"13.19"}]
["GO-BP","GO:0001756","somitogenesis",{"v":0.000231575,"d":"2.32E-04"},{"v":0.001809768,"d":"1.81E-03"},{"v":0.000703015,"d":"7.03E-04"},"TP53/SMAD4/ATM",3,{"v":25.00446429,"d":"25.00"}]
["GO-BP","GO:0010821","regulation of mitochondrion organization",{"v":0.000238196,"d":"2.38E-04"},{"v":0.001855692,"d":"1.86E-03"},{"v":0.000720855,"d":"7.21E-04"},"MAPK8/TP53/PRKAA1/AKT1",4,{"v":13.0377095,"d":"13.04"}]
["GO-BP","GO:0051251","positive regulation of lymphocyte activation",{"v":0.000240747,"d":"2.41E-04"},{"v":0.00186973,"d":"1.87E-03"},{"v":0.000726308,"d":"7.26E-04"},"PTPN6/PTPN11/ZAP70/STAT6/AKT1",5,{"v":8.734094311,"d":"8.73"}]
["GO-BP","GO:0071479","cellular response to ionizing radiation",{"v":0.00024151,"d":"2.42E-04"},{"v":0.00186983,"d":"1.87E-03"},{"v":0.000726347,"d":"7.26E-04"},"MAPK14/TP53/ATM",3,{"v":24.65228873,"d":"24.65"}]
["GO-BP","GO:0043534","blood vessel endothelial cell migration",{"v":0.000243317,"d":"2.43E-04"},{"v":0.0018779859999999999,"d":"1.88E-03"},{"v":0.000729515,"d":"7.30E-04"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":12.96527778,"d":"12.97"}]
["GO-BP","GO:0007596","blood coagulation",{"v":0.000247487,"d":"2.47E-04"},{"v":0.001904278,"d":"1.90E-03"},{"v":0.000739728,"d":"7.40E-04"},"PTPN6/HSPB1/PTPN11/MAPK1/JAK2",5,{"v":8.682105655,"d":"8.68"}]
["GO-BP","GO:0035019","somatic stem cell population maintenance",{"v":0.000251718,"d":"2.52E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"SMAD4/STAT3/SMAD2",3,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:1903747","regulation of establishment of protein localization to mitochondrion",{"v":0.000251718,"d":"2.52E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"MAPK8/TP53/PRKAA1",3,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0014841","skeletal muscle satellite cell proliferation",{"v":0.000255684,"d":"2.56E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"STAT3/JAK2",2,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0014857","regulation of skeletal muscle cell proliferation",{"v":0.000255684,"d":"2.56E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"STAT3/JAK2",2,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0048308","organelle inheritance",{"v":0.000255684,"d":"2.56E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"MAP2K1/MAPK1",2,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0048313","Golgi inheritance",{"v":0.000255684,"d":"2.56E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"MAP2K1/MAPK1",2,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0070672","response to interleukin-15",{"v":0.000255684,"d":"2.56E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"STAT3/STAT5A",2,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:1905050","positive regulation of metallopeptidase activity",{"v":0.000255684,"d":"2.56E-04"},{"v":0.001919943,"d":"1.92E-03"},{"v":0.000745814,"d":"7.46E-04"},"MAPK14/STAT3",2,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0038061","NIK/NF-kappaB signaling",{"v":0.000259158,"d":"2.59E-04"},{"v":0.001934376,"d":"1.93E-03"},{"v":0.00075142,"d":"7.51E-04"},"NFKBIA/AKT1/PSMD9/EGFR",4,{"v":12.75273224,"d":"12.75"}]
["GO-BP","GO:0043487","regulation of RNA stability",{"v":0.000259158,"d":"2.59E-04"},{"v":0.001934376,"d":"1.93E-03"},{"v":0.00075142,"d":"7.51E-04"},"MAPK14/HSPB1/AKT1/PSMD9",4,{"v":12.75273224,"d":"12.75"}]
["GO-BP","GO:1901983","regulation of protein acetylation",{"v":0.000262201,"d":"2.62E-04"},{"v":0.001951242,"d":"1.95E-03"},{"v":0.000757972,"d":"7.58E-04"},"SMAD4/RPS6KA4/PRKAA1",3,{"v":23.97688356,"d":"23.98"}]
["GO-BP","GO:0048639","positive regulation of developmental growth",{"v":0.0002646,"d":"2.65E-04"},{"v":0.00196013,"d":"1.96E-03"},{"v":0.000761424,"d":"7.61E-04"},"MAPK14/MAPK1/CREB1/AKT1",4,{"v":12.68342391,"d":"12.68"}]
["GO-BP","GO:0007599","hemostasis",{"v":0.000264967,"d":"2.65E-04"},{"v":0.00196013,"d":"1.96E-03"},{"v":0.000761424,"d":"7.61E-04"},"PTPN6/HSPB1/PTPN11/MAPK1/JAK2",5,{"v":8.554802053,"d":"8.55"}]
["GO-BP","GO:0050817","coagulation",{"v":0.000268574,"d":"2.69E-04"},{"v":0.001980928,"d":"1.98E-03"},{"v":0.000769504,"d":"7.70E-04"},"PTPN6/HSPB1/PTPN11/MAPK1/JAK2",5,{"v":8.529788012,"d":"8.53"}]
["GO-BP","GO:1903708","positive regulation of hemopoiesis",{"v":0.000270123,"d":"2.70E-04"},{"v":0.001986481,"d":"1.99E-03"},{"v":0.000771661,"d":"7.72E-04"},"MAPK14/STAT3/CREB1/ZAP70",4,{"v":12.61486486,"d":"12.61"}]
["GO-BP","GO:0001101","response to acid chemical",{"v":0.000272217,"d":"2.72E-04"},{"v":0.001995584,"d":"2.00E-03"},{"v":0.000775197,"d":"7.75E-04"},"ATM/CREB1/PRKAA1/AKT1/EGFR",5,{"v":8.504919825,"d":"8.50"}]
["GO-BP","GO:1900182","positive regulation of protein localization to nucleus",{"v":0.000272962,"d":"2.73E-04"},{"v":0.001995584,"d":"2.00E-03"},{"v":0.000775197,"d":"7.75E-04"},"MAPK14/MAPK1/AKT1",3,{"v":23.65287162,"d":"23.65"}]
["GO-BP","GO:1905475","regulation of protein localization to membrane",{"v":0.000281418,"d":"2.81E-04"},{"v":0.002051391,"d":"2.05E-03"},{"v":0.000796876,"d":"7.97E-04"},"MAPK8/TP53/AKT1/EGFR",4,{"v":12.47994652,"d":"12.48"}]
["GO-BP","GO:0150076","neuroinflammatory response",{"v":0.000284005,"d":"2.84E-04"},{"v":0.00206421,"d":"2.06E-03"},{"v":0.000801855,"d":"8.02E-04"},"ATM/JAK2/EGFR",3,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:0014856","skeletal muscle cell proliferation",{"v":0.000294705,"d":"2.95E-04"},{"v":0.002115702,"d":"2.12E-03"},{"v":0.000821857,"d":"8.22E-04"},"STAT3/JAK2",2,{"v":77.79166667,"d":"77.79"}]
["GO-BP","GO:0045898","regulation of RNA polymerase II transcription preinitiation complex assembly",{"v":0.000294705,"d":"2.95E-04"},{"v":0.002115702,"d":"2.12E-03"},{"v":0.000821857,"d":"8.22E-04"},"TP53/CREB1",2,{"v":77.79166667,"d":"77.79"}]
["GO-BP","GO:0051770","positive regulation of nitric-oxide synthase biosynthetic process",{"v":0.000294705,"d":"2.95E-04"},{"v":0.002115702,"d":"2.12E-03"},{"v":0.000821857,"d":"8.22E-04"},"MAP2K6/JAK2",2,{"v":77.79166667,"d":"77.79"}]
["GO-BP","GO:1903358","regulation of Golgi organization",{"v":0.000294705,"d":"2.95E-04"},{"v":0.002115702,"d":"2.12E-03"},{"v":0.000821857,"d":"8.22E-04"},"MAP2K1/MAPK1",2,{"v":77.79166667,"d":"77.79"}]
["GO-BP","GO:0046902","regulation of mitochondrial membrane permeability",{"v":0.000295333,"d":"2.95E-04"},{"v":0.002115702,"d":"2.12E-03"},{"v":0.000821857,"d":"8.22E-04"},"MAPK8/TP53/STAT3",3,{"v":23.03042763,"d":"23.03"}]
["GO-BP","GO:0060759","regulation of response to cytokine stimulus",{"v":0.000298993,"d":"2.99E-04"},{"v":0.002135786,"d":"2.14E-03"},{"v":0.000829659,"d":"8.30E-04"},"PTPN6/PTPN11/JAK2/TBK1",4,{"v":12.28289474,"d":"12.28"}]
["GO-BP","GO:0071478","cellular response to radiation",{"v":0.000305022,"d":"3.05E-04"},{"v":0.00216777,"d":"2.17E-03"},{"v":0.000842083,"d":"8.42E-04"},"MAPK14/TP53/EIF2S1/ATM",4,{"v":12.21858639,"d":"12.22"}]
["GO-BP","GO:0010631","epithelial cell migration",{"v":0.000306729,"d":"3.07E-04"},{"v":0.00216777,"d":"2.17E-03"},{"v":0.000842083,"d":"8.42E-04"},"HSPB1/MAP2K3/PTPN11/STAT5A/AKT1",5,{"v":8.287464489,"d":"8.29"}]
["GO-BP","GO:0016575","histone deacetylation",{"v":0.000306949,"d":"3.07E-04"},{"v":0.00216777,"d":"2.17E-03"},{"v":0.000842083,"d":"8.42E-04"},"MAPK8/TP53/RBM14",3,{"v":22.73133117,"d":"22.73"}]
["GO-BP","GO:0032481","positive regulation of type I interferon production",{"v":0.000306949,"d":"3.07E-04"},{"v":0.00216777,"d":"2.17E-03"},{"v":0.000842083,"d":"8.42E-04"},"PTPN11/STAT6/TBK1",3,{"v":22.73133117,"d":"22.73"}]
["GO-BP","GO:0050731","positive regulation of peptidyl-tyrosine phosphorylation",{"v":0.000311139,"d":"3.11E-04"},{"v":0.002191157,"d":"2.19E-03"},{"v":0.000851168,"d":"8.51E-04"},"TP53/PTPN11/STAT3/JAK2",4,{"v":12.15494792,"d":"12.15"}]
["GO-BP","GO:0007219","Notch signaling pathway",{"v":0.000317343,"d":"3.17E-04"},{"v":0.002214827,"d":"2.21E-03"},{"v":0.000860363,"d":"8.60E-04"},"STAT3/NFKBIA/AKT1/EGFR",4,{"v":12.09196891,"d":"12.09"}]
["GO-BP","GO:1901654","response to ketone",{"v":0.000317343,"d":"3.17E-04"},{"v":0.002214827,"d":"2.21E-03"},{"v":0.000860363,"d":"8.60E-04"},"EIF4EBP1/PRKAA1/AKT1/EGFR",4,{"v":12.09196891,"d":"12.09"}]
["GO-BP","GO:0010827","regulation of glucose transmembrane transport",{"v":0.000318856,"d":"3.19E-04"},{"v":0.002214827,"d":"2.21E-03"},{"v":0.000860363,"d":"8.60E-04"},"MAPK14/PTPN11/AKT1",3,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:0090398","cellular senescence",{"v":0.000318856,"d":"3.19E-04"},{"v":0.002214827,"d":"2.21E-03"},{"v":0.000860363,"d":"8.60E-04"},"MAPK14/TP53/MAP2K1",3,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:0090132","epithelium migration",{"v":0.000318942,"d":"3.19E-04"},{"v":0.002214827,"d":"2.21E-03"},{"v":0.000860363,"d":"8.60E-04"},"HSPB1/MAP2K3/PTPN11/STAT5A/AKT1",5,{"v":8.217429577,"d":"8.22"}]
["GO-BP","GO:0006446","regulation of translational initiation",{"v":0.000331057,"d":"3.31E-04"},{"v":0.002292568,"d":"2.29E-03"},{"v":0.000890562,"d":"8.91E-04"},"HSPB1/EIF2S1/EIF4EBP1",3,{"v":22.15585443,"d":"22.16"}]
["GO-BP","GO:0002295","T-helper cell lineage commitment",{"v":0.000336445,"d":"3.36E-04"},{"v":0.002310626,"d":"2.31E-03"},{"v":0.000897577,"d":"8.98E-04"},"STAT3/STAT6",2,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0031958","corticosteroid receptor signaling pathway",{"v":0.000336445,"d":"3.36E-04"},{"v":0.002310626,"d":"2.31E-03"},{"v":0.000897577,"d":"8.98E-04"},"RBM14/JAK2",2,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0071380","cellular response to prostaglandin E stimulus",{"v":0.000336445,"d":"3.36E-04"},{"v":0.002310626,"d":"2.31E-03"},{"v":0.000897577,"d":"8.98E-04"},"PRKAA1/AKT1",2,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0090130","tissue migration",{"v":0.000344475,"d":"3.44E-04"},{"v":0.002359278,"d":"2.36E-03"},{"v":0.000916476,"d":"9.16E-04"},"HSPB1/MAP2K3/PTPN11/STAT5A/AKT1",5,{"v":8.080851801,"d":"8.08"}]
["GO-BP","GO:0006109","regulation of carbohydrate metabolic process",{"v":0.000356451,"d":"3.56E-04"},{"v":0.002427957,"d":"2.43E-03"},{"v":0.000943155,"d":"9.43E-04"},"TP53/STAT3/PRKAA1/AKT1",4,{"v":11.72738693,"d":"11.73"}]
["GO-BP","GO:0061013","regulation of mRNA catabolic process",{"v":0.000356451,"d":"3.56E-04"},{"v":0.002427957,"d":"2.43E-03"},{"v":0.000943155,"d":"9.43E-04"},"MAPK14/HSPB1/AKT1/PSMD9",4,{"v":11.72738693,"d":"11.73"}]
["GO-BP","GO:0006402","mRNA catabolic process",{"v":0.00035781,"d":"3.58E-04"},{"v":0.002430573,"d":"2.43E-03"},{"v":0.000944171,"d":"9.44E-04"},"MAPK14/HSPB1/ATM/AKT1/PSMD9",5,{"v":8.014251374,"d":"8.01"}]
["GO-BP","GO:0050852","T cell receptor signaling pathway",{"v":0.000377248,"d":"3.77E-04"},{"v":0.002545777,"d":"2.55E-03"},{"v":0.000988922,"d":"9.89E-04"},"PTPN6/MAPK1/ZAP70/PSMD9",4,{"v":11.55321782,"d":"11.55"}]
["GO-BP","GO:0050870","positive regulation of T cell activation",{"v":0.000377248,"d":"3.77E-04"},{"v":0.002545777,"d":"2.55E-03"},{"v":0.000988922,"d":"9.89E-04"},"PTPN6/PTPN11/ZAP70/AKT1",4,{"v":11.55321782,"d":"11.55"}]
["GO-BP","GO:0008340","determination of adult lifespan",{"v":0.000380896,"d":"3.81E-04"},{"v":0.002545777,"d":"2.55E-03"},{"v":0.000988922,"d":"9.89E-04"},"TP53/ATM",2,{"v":68.63970588,"d":"68.64"}]
["GO-BP","GO:0035855","megakaryocyte development",{"v":0.000380896,"d":"3.81E-04"},{"v":0.002545777,"d":"2.55E-03"},{"v":0.000988922,"d":"9.89E-04"},"PTPN6/PTPN11",2,{"v":68.63970588,"d":"68.64"}]
["GO-BP","GO:0043373","CD4-positive, alpha-beta T cell lineage commitment",{"v":0.000380896,"d":"3.81E-04"},{"v":0.002545777,"d":"2.55E-03"},{"v":0.000988922,"d":"9.89E-04"},"STAT3/STAT6",2,{"v":68.63970588,"d":"68.64"}]
["GO-BP","GO:2000641","regulation of early endosome to late endosome transport",{"v":0.000380896,"d":"3.81E-04"},{"v":0.002545777,"d":"2.55E-03"},{"v":0.000988922,"d":"9.89E-04"},"MAP2K1/MAPK1",2,{"v":68.63970588,"d":"68.64"}]
["GO-BP","GO:0048145","regulation of fibroblast proliferation",{"v":0.000382867,"d":"3.83E-04"},{"v":0.002552103,"d":"2.55E-03"},{"v":0.00099138,"d":"9.91E-04"},"TP53/CREB1/EGFR",3,{"v":21.08810241,"d":"21.09"}]
["GO-BP","GO:0006006","glucose metabolic process",{"v":0.000391588,"d":"3.92E-04"},{"v":0.002603276,"d":"2.60E-03"},{"v":0.001011258,"d":"1.01E-03"},"MAPK14/TP53/PRKAA1/AKT1",4,{"v":11.43995098,"d":"11.44"}]
["GO-BP","GO:0010507","negative regulation of autophagy",{"v":0.000396586,"d":"3.97E-04"},{"v":0.002615576,"d":"2.62E-03"},{"v":0.001016036,"d":"1.02E-03"},"TP53/STAT3/AKT1",3,{"v":20.83705357,"d":"20.84"}]
["GO-BP","GO:0046889","positive regulation of lipid biosynthetic process",{"v":0.000396586,"d":"3.97E-04"},{"v":0.002615576,"d":"2.62E-03"},{"v":0.001016036,"d":"1.02E-03"},"CREB1/PRKAA1/AKT1",3,{"v":20.83705357,"d":"20.84"}]
["GO-BP","GO:0048144","fibroblast proliferation",{"v":0.000396586,"d":"3.97E-04"},{"v":0.002615576,"d":"2.62E-03"},{"v":0.001016036,"d":"1.02E-03"},"TP53/CREB1/EGFR",3,{"v":20.83705357,"d":"20.84"}]
["GO-BP","GO:0050727","regulation of inflammatory response",{"v":0.000405107,"d":"4.05E-04"},{"v":0.002664726,"d":"2.66E-03"},{"v":0.001035129,"d":"1.04E-03"},"MAPK14/ATM/JAK2/NFKBIA/EGFR",5,{"v":7.799966578,"d":"7.80"}]
["GO-BP","GO:0050679","positive regulation of epithelial cell proliferation",{"v":0.000406314,"d":"4.06E-04"},{"v":0.002665632,"d":"2.67E-03"},{"v":0.001035481,"d":"1.04E-03"},"STAT3/STAT5A/AKT1/EGFR",4,{"v":11.3288835,"d":"11.33"}]
["GO-BP","GO:0030073","insulin secretion",{"v":0.000413823,"d":"4.14E-04"},{"v":0.002707774,"d":"2.71E-03"},{"v":0.001051851,"d":"1.05E-03"},"PTPN11/JAK2/SMAD2/PSMD9",4,{"v":11.27415459,"d":"11.27"}]
["GO-BP","GO:0090276","regulation of peptide hormone secretion",{"v":0.000421432,"d":"4.21E-04"},{"v":0.00274316,"d":"2.74E-03"},{"v":0.001065597,"d":"1.07E-03"},"PTPN11/JAK2/PSMD9/EGFR",4,{"v":11.21995192,"d":"11.22"}]
["GO-BP","GO:1901215","negative regulation of neuron death",{"v":0.000421432,"d":"4.21E-04"},{"v":0.00274316,"d":"2.74E-03"},{"v":0.001065597,"d":"1.07E-03"},"STAT3/JAK2/CREB1/AKT1",4,{"v":11.21995192,"d":"11.22"}]
["GO-BP","GO:0032760","positive regulation of tumor necrosis factor production",{"v":0.000424965,"d":"4.25E-04"},{"v":0.002744654,"d":"2.74E-03"},{"v":0.001066178,"d":"1.07E-03"},"HSPB1/PTPN11/JAK2",3,{"v":20.35247093,"d":"20.35"}]
["GO-BP","GO:0070542","response to fatty acid",{"v":0.000424965,"d":"4.25E-04"},{"v":0.002744654,"d":"2.74E-03"},{"v":0.001066178,"d":"1.07E-03"},"CREB1/PRKAA1/AKT1",3,{"v":20.35247093,"d":"20.35"}]
["GO-BP","GO:0090559","regulation of membrane permeability",{"v":0.000424965,"d":"4.25E-04"},{"v":0.002744654,"d":"2.74E-03"},{"v":0.001066178,"d":"1.07E-03"},"MAPK8/TP53/STAT3",3,{"v":20.35247093,"d":"20.35"}]
["GO-BP","GO:0035994","response to muscle stretch",{"v":0.00042805,"d":"4.28E-04"},{"v":0.002750331,"d":"2.75E-03"},{"v":0.001068383,"d":"1.07E-03"},"MAPK14/NFKBIA",2,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0043555","regulation of translation in response to stress",{"v":0.00042805,"d":"4.28E-04"},{"v":0.002750331,"d":"2.75E-03"},{"v":0.001068383,"d":"1.07E-03"},"RPS6KA1/EIF2S1",2,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0002696","positive regulation of leukocyte activation",{"v":0.000435673,"d":"4.36E-04"},{"v":0.002792116,"d":"2.79E-03"},{"v":0.001084614,"d":"1.08E-03"},"PTPN6/PTPN11/ZAP70/STAT6/AKT1",5,{"v":7.676809211,"d":"7.68"}]
["GO-BP","GO:0043470","regulation of carbohydrate catabolic process",{"v":0.000439631,"d":"4.40E-04"},{"v":0.002810254,"d":"2.81E-03"},{"v":0.00109166,"d":"1.09E-03"},"TP53/STAT3/PRKAA1",3,{"v":20.11853448,"d":"20.12"}]
["GO-BP","GO:1903557","positive regulation of tumor necrosis factor superfamily cytokine production",{"v":0.000454618,"d":"4.55E-04"},{"v":0.002898627,"d":"2.90E-03"},{"v":0.001125989,"d":"1.13E-03"},"HSPB1/PTPN11/JAK2",3,{"v":19.88991477,"d":"19.89"}]
["GO-BP","GO:0061053","somite development",{"v":0.00046993,"d":"4.70E-04"},{"v":0.002988614,"d":"2.99E-03"},{"v":0.001160945,"d":"1.16E-03"},"TP53/SMAD4/ATM",3,{"v":19.66643258,"d":"19.67"}]
["GO-BP","GO:0002363","alpha-beta T cell lineage commitment",{"v":0.000477897,"d":"4.78E-04"},{"v":0.002993461,"d":"2.99E-03"},{"v":0.001162828,"d":"1.16E-03"},"STAT3/STAT6",2,{"v":61.41447368,"d":"61.41"}]
["GO-BP","GO:0034063","stress granule assembly",{"v":0.000477897,"d":"4.78E-04"},{"v":0.002993461,"d":"2.99E-03"},{"v":0.001162828,"d":"1.16E-03"},"EIF2S1/PRKAA1",2,{"v":61.41447368,"d":"61.41"}]
["GO-BP","GO:0045947","negative regulation of translational initiation",{"v":0.000477897,"d":"4.78E-04"},{"v":0.002993461,"d":"2.99E-03"},{"v":0.001162828,"d":"1.16E-03"},"EIF2S1/EIF4EBP1",2,{"v":61.41447368,"d":"61.41"}]
["GO-BP","GO:0060438","trachea development",{"v":0.000477897,"d":"4.78E-04"},{"v":0.002993461,"d":"2.99E-03"},{"v":0.001162828,"d":"1.16E-03"},"MAP2K1/MAPK1",2,{"v":61.41447368,"d":"61.41"}]
["GO-BP","GO:0060716","labyrinthine layer blood vessel development",{"v":0.000477897,"d":"4.78E-04"},{"v":0.002993461,"d":"2.99E-03"},{"v":0.001162828,"d":"1.16E-03"},"MAPK1/AKT1",2,{"v":61.41447368,"d":"61.41"}]
["GO-BP","GO:1902176","negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway",{"v":0.000477897,"d":"4.78E-04"},{"v":0.002993461,"d":"2.99E-03"},{"v":0.001162828,"d":"1.16E-03"},"HSPB1/AKT1",2,{"v":61.41447368,"d":"61.41"}]
["GO-BP","GO:0000075","cell cycle checkpoint",{"v":0.000485952,"d":"4.86E-04"},{"v":0.003028694,"d":"3.03E-03"},{"v":0.001176515,"d":"1.18E-03"},"MAPK14/TP53/PTPN11/ATM",4,{"v":10.80439815,"d":"10.80"}]
["GO-BP","GO:0032869","cellular response to insulin stimulus",{"v":0.000485952,"d":"4.86E-04"},{"v":0.003028694,"d":"3.03E-03"},{"v":0.001176515,"d":"1.18E-03"},"PTPN11/EIF4EBP1/PRKAA1/AKT1",4,{"v":10.80439815,"d":"10.80"}]
["GO-BP","GO:0014706","striated muscle tissue development",{"v":0.000490462,"d":"4.90E-04"},{"v":0.003049179,"d":"3.05E-03"},{"v":0.001184472,"d":"1.18E-03"},"MAPK14/SMAD4/MAPK1/CREB1/PRKAA1",5,{"v":7.479967949,"d":"7.48"}]
["GO-BP","GO:0060348","bone development",{"v":0.000494484,"d":"4.94E-04"},{"v":0.003066541,"d":"3.07E-03"},{"v":0.001191217,"d":"1.19E-03"},"PTPN6/TP53/PTPN11/SMAD5",4,{"v":10.75460829,"d":"10.75"}]
["GO-BP","GO:0045639","positive regulation of myeloid cell differentiation",{"v":0.000501541,"d":"5.02E-04"},{"v":0.003102583,"d":"3.10E-03"},{"v":0.001205217,"d":"1.21E-03"},"MAPK14/STAT3/CREB1",3,{"v":19.2342033,"d":"19.23"}]
["GO-BP","GO:1903039","positive regulation of leukocyte cell-cell adhesion",{"v":0.000503124,"d":"5.03E-04"},{"v":0.003104671,"d":"3.10E-03"},{"v":0.001206028,"d":"1.21E-03"},"PTPN6/PTPN11/ZAP70/AKT1",4,{"v":10.70527523,"d":"10.71"}]
["GO-BP","GO:0010639","negative regulation of organelle organization",{"v":0.000507871,"d":"5.08E-04"},{"v":0.003126228,"d":"3.13E-03"},{"v":0.001214402,"d":"1.21E-03"},"TP53/RBM14/SMAD4/ATM/AKT1",5,{"v":7.422868957,"d":"7.42"}]
["GO-BP","GO:0009952","anterior/posterior pattern specification",{"v":0.00051187,"d":"5.12E-04"},{"v":0.003143084,"d":"3.14E-03"},{"v":0.00122095,"d":"1.22E-03"},"TP53/SMAD4/ATM/SMAD2",4,{"v":10.65639269,"d":"10.66"}]
["GO-BP","GO:0030220","platelet formation",{"v":0.000530429,"d":"5.30E-04"},{"v":0.003201837,"d":"3.20E-03"},{"v":0.001243773,"d":"1.24E-03"},"PTPN6/PTPN11",2,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0032495","response to muramyl dipeptide",{"v":0.000530429,"d":"5.30E-04"},{"v":0.003201837,"d":"3.20E-03"},{"v":0.001243773,"d":"1.24E-03"},"MAPK14/NFKBIA",2,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0042535","positive regulation of tumor necrosis factor biosynthetic process",{"v":0.000530429,"d":"5.30E-04"},{"v":0.003201837,"d":"3.20E-03"},{"v":0.001243773,"d":"1.24E-03"},"HSPB1/JAK2",2,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0043369","CD4-positive or CD8-positive, alpha-beta T cell lineage commitment",{"v":0.000530429,"d":"5.30E-04"},{"v":0.003201837,"d":"3.20E-03"},{"v":0.001243773,"d":"1.24E-03"},"STAT3/STAT6",2,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0051767","nitric-oxide synthase biosynthetic process",{"v":0.000530429,"d":"5.30E-04"},{"v":0.003201837,"d":"3.20E-03"},{"v":0.001243773,"d":"1.24E-03"},"MAP2K6/JAK2",2,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0051769","regulation of nitric-oxide synthase biosynthetic process",{"v":0.000530429,"d":"5.30E-04"},{"v":0.003201837,"d":"3.20E-03"},{"v":0.001243773,"d":"1.24E-03"},"MAP2K6/JAK2",2,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0060261","positive regulation of transcription initiation from RNA polymerase II promoter",{"v":0.000530429,"d":"5.30E-04"},{"v":0.003201837,"d":"3.20E-03"},{"v":0.001243773,"d":"1.24E-03"},"TP53/CREB1",2,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0006401","RNA catabolic process",{"v":0.000531805,"d":"5.32E-04"},{"v":0.003202394,"d":"3.20E-03"},{"v":0.001243989,"d":"1.24E-03"},"MAPK14/HSPB1/ATM/AKT1/PSMD9",5,{"v":7.348079345,"d":"7.35"}]
["GO-BP","GO:0036473","cell death in response to oxidative stress",{"v":0.000534484,"d":"5.34E-04"},{"v":0.00321077,"d":"3.21E-03"},{"v":0.001247243,"d":"1.25E-03"},"HSPB1/JAK2/AKT1",3,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:0001503","ossification",{"v":0.00053792,"d":"5.38E-04"},{"v":0.00322364,"d":"3.22E-03"},{"v":0.001252243,"d":"1.25E-03"},"MAPK14/SMAD5/MAPK1/AKT1/EGFR",5,{"v":7.329616834,"d":"7.33"}]
["GO-BP","GO:1901216","positive regulation of neuron death",{"v":0.000551464,"d":"5.51E-04"},{"v":0.003296879,"d":"3.30E-03"},{"v":0.001280693,"d":"1.28E-03"},"TP53/EIF2S1/ATM",3,{"v":18.62034574,"d":"18.62"}]
["GO-BP","GO:0034249","negative regulation of cellular amide metabolic process",{"v":0.000576163,"d":"5.76E-04"},{"v":0.003436301,"d":"3.44E-03"},{"v":0.001334852,"d":"1.33E-03"},"EIF2S1/STAT3/EIF4EBP1/PRKAA1",4,{"v":10.32632743,"d":"10.33"}]
["GO-BP","GO:0021697","cerebellar cortex formation",{"v":0.000585636,"d":"5.86E-04"},{"v":0.003464507,"d":"3.46E-03"},{"v":0.001345809,"d":"1.35E-03"},"MAP2K1/PTPN11",2,{"v":55.56547619,"d":"55.57"}]
["GO-BP","GO:0036344","platelet morphogenesis",{"v":0.000585636,"d":"5.86E-04"},{"v":0.003464507,"d":"3.46E-03"},{"v":0.001345809,"d":"1.35E-03"},"PTPN6/PTPN11",2,{"v":55.56547619,"d":"55.57"}]
["GO-BP","GO:0090277","positive regulation of peptide hormone secretion",{"v":0.000586451,"d":"5.86E-04"},{"v":0.003464507,"d":"3.46E-03"},{"v":0.001345809,"d":"1.35E-03"},"JAK2/PSMD9/EGFR",3,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:0097327","response to antineoplastic agent",{"v":0.000586451,"d":"5.86E-04"},{"v":0.003464507,"d":"3.46E-03"},{"v":0.001345809,"d":"1.35E-03"},"EIF4EBP1/PRKAA1/EGFR",3,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:2001233","regulation of apoptotic signaling pathway",{"v":0.000588767,"d":"5.89E-04"},{"v":0.003469969,"d":"3.47E-03"},{"v":0.001347931,"d":"1.35E-03"},"MAPK8/TP53/HSPB1/JAK2/AKT1",5,{"v":7.185190887,"d":"7.19"}]
["GO-BP","GO:0060537","muscle tissue development",{"v":0.000602027,"d":"6.02E-04"},{"v":0.003539747,"d":"3.54E-03"},{"v":0.001375036,"d":"1.38E-03"},"MAPK14/SMAD4/MAPK1/CREB1/PRKAA1",5,{"v":7.149969363,"d":"7.15"}]
["GO-BP","GO:0001657","ureteric bud development",{"v":0.000604465,"d":"6.04E-04"},{"v":0.003542884,"d":"3.54E-03"},{"v":0.001376255,"d":"1.38E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":18.04445876,"d":"18.04"}]
["GO-BP","GO:0010594","regulation of endothelial cell migration",{"v":0.000605403,"d":"6.05E-04"},{"v":0.003542884,"d":"3.54E-03"},{"v":0.001376255,"d":"1.38E-03"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":10.19104803,"d":"10.19"}]
["GO-BP","GO:0007517","muscle organ development",{"v":0.00061551,"d":"6.16E-04"},{"v":0.003593599,"d":"3.59E-03"},{"v":0.001395955,"d":"1.40E-03"},"MAPK14/SMAD4/MAPK1/CREB1/PRKAA1",5,{"v":7.115091463,"d":"7.12"}]
["GO-BP","GO:0072163","mesonephric epithelium development",{"v":0.000622829,"d":"6.23E-04"},{"v":0.003619377,"d":"3.62E-03"},{"v":0.001405969,"d":"1.41E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":17.86033163,"d":"17.86"}]
["GO-BP","GO:0072164","mesonephric tubule development",{"v":0.000622829,"d":"6.23E-04"},{"v":0.003619377,"d":"3.62E-03"},{"v":0.001405969,"d":"1.41E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":17.86033163,"d":"17.86"}]
["GO-BP","GO:0019395","fatty acid oxidation",{"v":0.000641547,"d":"6.42E-04"},{"v":0.003696481,"d":"3.70E-03"},{"v":0.001435921,"d":"1.44E-03"},"MAPK14/PRKAA1/AKT1",3,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:0062014","negative regulation of small molecule metabolic process",{"v":0.000641547,"d":"6.42E-04"},{"v":0.003696481,"d":"3.70E-03"},{"v":0.001435921,"d":"1.44E-03"},"TP53/STAT3/AKT1",3,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:0030878","thyroid gland development",{"v":0.000643511,"d":"6.44E-04"},{"v":0.003696481,"d":"3.70E-03"},{"v":0.001435921,"d":"1.44E-03"},"MAP2K1/MAPK1",2,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0031281","positive regulation of cyclase activity",{"v":0.000643511,"d":"6.44E-04"},{"v":0.003696481,"d":"3.70E-03"},{"v":0.001435921,"d":"1.44E-03"},"MAPK14/MAPK8",2,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0071379","cellular response to prostaglandin stimulus",{"v":0.000643511,"d":"6.44E-04"},{"v":0.003696481,"d":"3.70E-03"},{"v":0.001435921,"d":"1.44E-03"},"PRKAA1/AKT1",2,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0048738","cardiac muscle tissue development",{"v":0.000646013,"d":"6.46E-04"},{"v":0.003702321,"d":"3.70E-03"},{"v":0.001438189,"d":"1.44E-03"},"MAPK14/SMAD4/MAPK1/CREB1",4,{"v":10.01609442,"d":"10.02"}]
["GO-BP","GO:0001558","regulation of cell growth",{"v":0.000657328,"d":"6.57E-04"},{"v":0.00375853,"d":"3.76E-03"},{"v":0.001460024,"d":"1.46E-03"},"TP53/RPS6KA1/SMAD4/AKT1/EGFR",5,{"v":7.012469952,"d":"7.01"}]
["GO-BP","GO:0035282","segmentation",{"v":0.00066062,"d":"6.61E-04"},{"v":0.003760106,"d":"3.76E-03"},{"v":0.001460636,"d":"1.46E-03"},"TP53/SMAD4/ATM",3,{"v":17.503125,"d":"17.50"}]
["GO-BP","GO:0070498","interleukin-1-mediated signaling pathway",{"v":0.00066062,"d":"6.61E-04"},{"v":0.003760106,"d":"3.76E-03"},{"v":0.001460636,"d":"1.46E-03"},"RPS6KA4/NFKBIA/PSMD9",3,{"v":17.503125,"d":"17.50"}]
["GO-BP","GO:0034440","lipid oxidation",{"v":0.000680053,"d":"6.80E-04"},{"v":0.003835683,"d":"3.84E-03"},{"v":0.001489994,"d":"1.49E-03"},"MAPK14/PRKAA1/AKT1",3,{"v":17.32982673,"d":"17.33"}]
["GO-BP","GO:0046632","alpha-beta T cell differentiation",{"v":0.000680053,"d":"6.80E-04"},{"v":0.003835683,"d":"3.84E-03"},{"v":0.001489994,"d":"1.49E-03"},"STAT3/ZAP70/STAT6",3,{"v":17.32982673,"d":"17.33"}]
["GO-BP","GO:0048661","positive regulation of smooth muscle cell proliferation",{"v":0.000680053,"d":"6.80E-04"},{"v":0.003835683,"d":"3.84E-03"},{"v":0.001489994,"d":"1.49E-03"},"JAK2/AKT1/EGFR",3,{"v":17.32982673,"d":"17.33"}]
["GO-BP","GO:1903426","regulation of reactive oxygen species biosynthetic process",{"v":0.000680053,"d":"6.80E-04"},{"v":0.003835683,"d":"3.84E-03"},{"v":0.001489994,"d":"1.49E-03"},"STAT3/JAK2/AKT1",3,{"v":17.32982673,"d":"17.33"}]
["GO-BP","GO:0032872","regulation of stress-activated MAPK cascade",{"v":0.000688524,"d":"6.89E-04"},{"v":0.003874697,"d":"3.87E-03"},{"v":0.00150515,"d":"1.51E-03"},"MAP2K1/MAPK1/AKT1/EGFR",4,{"v":9.847046414,"d":"9.85"}]
["GO-BP","GO:0001823","mesonephros development",{"v":0.000699847,"d":"7.00E-04"},{"v":0.003920717,"d":"3.92E-03"},{"v":0.001523026,"d":"1.52E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":17.15992647,"d":"17.16"}]
["GO-BP","GO:0021549","cerebellum development",{"v":0.000699847,"d":"7.00E-04"},{"v":0.003920717,"d":"3.92E-03"},{"v":0.001523026,"d":"1.52E-03"},"TP53/MAP2K1/PTPN11",3,{"v":17.15992647,"d":"17.16"}]
["GO-BP","GO:0034695","response to prostaglandin E",{"v":0.000704044,"d":"7.04E-04"},{"v":0.003926582,"d":"3.93E-03"},{"v":0.001525305,"d":"1.53E-03"},"PRKAA1/AKT1",2,{"v":50.73369565,"d":"50.73"}]
["GO-BP","GO:0050995","negative regulation of lipid catabolic process",{"v":0.000704044,"d":"7.04E-04"},{"v":0.003926582,"d":"3.93E-03"},{"v":0.001525305,"d":"1.53E-03"},"PRKAA1/AKT1",2,{"v":50.73369565,"d":"50.73"}]
["GO-BP","GO:0070302","regulation of stress-activated protein kinase signaling cascade",{"v":0.000710509,"d":"7.11E-04"},{"v":0.00395379,"d":"3.95E-03"},{"v":0.001535874,"d":"1.54E-03"},"MAP2K1/MAPK1/AKT1/EGFR",4,{"v":9.764644351,"d":"9.76"}]
["GO-BP","GO:0032091","negative regulation of protein binding",{"v":0.000720006,"d":"7.20E-04"},{"v":0.003997715,"d":"4.00E-03"},{"v":0.001552937,"d":"1.55E-03"},"MAPK8/EIF2S1/AKT1",3,{"v":16.99332524,"d":"16.99"}]
["GO-BP","GO:0030217","T cell differentiation",{"v":0.000721686,"d":"7.22E-04"},{"v":0.003998138,"d":"4.00E-03"},{"v":0.001553101,"d":"1.55E-03"},"TP53/STAT3/ZAP70/STAT6",4,{"v":9.723958333,"d":"9.72"}]
["GO-BP","GO:0042593","glucose homeostasis",{"v":0.000732987,"d":"7.33E-04"},{"v":0.004051744,"d":"4.05E-03"},{"v":0.001573925,"d":"1.57E-03"},"PTPN11/STAT3/PRKAA1/AKT1",4,{"v":9.683609959,"d":"9.68"}]
["GO-BP","GO:0033500","carbohydrate homeostasis",{"v":0.000744413,"d":"7.44E-04"},{"v":0.004105802,"d":"4.11E-03"},{"v":0.001594924,"d":"1.59E-03"},"PTPN11/STAT3/PRKAA1/AKT1",4,{"v":9.643595041,"d":"9.64"}]
["GO-BP","GO:0043254","regulation of protein-containing complex assembly",{"v":0.000755242,"d":"7.55E-04"},{"v":0.004147176,"d":"4.15E-03"},{"v":0.001610996,"d":"1.61E-03"},"TP53/PTPN11/ATM/CREB1/EIF4EBP1",5,{"v":6.799970862,"d":"6.80"}]
["GO-BP","GO:0062012","regulation of small molecule metabolic process",{"v":0.000755242,"d":"7.55E-04"},{"v":0.004147176,"d":"4.15E-03"},{"v":0.001610996,"d":"1.61E-03"},"TP53/STAT3/PRKAA1/AKT1/PSMD9",5,{"v":6.799970862,"d":"6.80"}]
["GO-BP","GO:0033138","positive regulation of peptidyl-serine phosphorylation",{"v":0.000761427,"d":"7.61E-04"},{"v":0.004171949,"d":"4.17E-03"},{"v":0.001620619,"d":"1.62E-03"},"TBK1/AKT1/EGFR",3,{"v":16.66964286,"d":"16.67"}]
["GO-BP","GO:0062009","secondary palate development",{"v":0.000767227,"d":"7.67E-04"},{"v":0.004178466,"d":"4.18E-03"},{"v":0.001623151,"d":"1.62E-03"},"SMAD4/SMAD2",2,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:1903649","regulation of cytoplasmic transport",{"v":0.000767227,"d":"7.67E-04"},{"v":0.004178466,"d":"4.18E-03"},{"v":0.001623151,"d":"1.62E-03"},"MAP2K1/MAPK1",2,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0019318","hexose metabolic process",{"v":0.000767644,"d":"7.68E-04"},{"v":0.004178466,"d":"4.18E-03"},{"v":0.001623151,"d":"1.62E-03"},"MAPK14/TP53/PRKAA1/AKT1",4,{"v":9.56454918,"d":"9.56"}]
["GO-BP","GO:0002286","T cell activation involved in immune response",{"v":0.000782695,"d":"7.83E-04"},{"v":0.004251106,"d":"4.25E-03"},{"v":0.001651368,"d":"1.65E-03"},"TP53/STAT3/STAT6",3,{"v":16.51238208,"d":"16.51"}]
["GO-BP","GO:0002683","negative regulation of immune system process",{"v":0.000803955,"d":"8.04E-04"},{"v":0.004357088,"d":"4.36E-03"},{"v":0.001692537,"d":"1.69E-03"},"PTPN6/ATM/STAT6/NFKBIA/AKT1",5,{"v":6.706178161,"d":"6.71"}]
["GO-BP","GO:0050804","modulation of chemical synaptic transmission",{"v":0.000812298,"d":"8.12E-04"},{"v":0.004392752,"d":"4.39E-03"},{"v":0.001706391,"d":"1.71E-03"},"MAPK1/STAT3/JAK2/CREB1/EGFR",5,{"v":6.690797018,"d":"6.69"}]
["GO-BP","GO:0071383","cellular response to steroid hormone stimulus",{"v":0.000815642,"d":"8.16E-04"},{"v":0.004401288,"d":"4.40E-03"},{"v":0.001709707,"d":"1.71E-03"},"RBM14/JAK2/EIF4EBP1/EGFR",4,{"v":9.410282258,"d":"9.41"}]
["GO-BP","GO:0099177","regulation of trans-synaptic signaling",{"v":0.000820705,"d":"8.21E-04"},{"v":0.004419046,"d":"4.42E-03"},{"v":0.001716605,"d":"1.72E-03"},"MAPK1/STAT3/JAK2/CREB1/EGFR",5,{"v":6.67548627,"d":"6.68"}]
["GO-BP","GO:1904659","glucose transmembrane transport",{"v":0.000826358,"d":"8.26E-04"},{"v":0.004430347,"d":"4.43E-03"},{"v":0.001720995,"d":"1.72E-03"},"MAPK14/PTPN11/AKT1",3,{"v":16.20659722,"d":"16.21"}]
["GO-BP","GO:2000278","regulation of DNA biosynthetic process",{"v":0.000826358,"d":"8.26E-04"},{"v":0.004430347,"d":"4.43E-03"},{"v":0.001720995,"d":"1.72E-03"},"TP53/MAPK1/ATM",3,{"v":16.20659722,"d":"16.21"}]
["GO-BP","GO:0009299","mRNA transcription",{"v":0.000833051,"d":"8.33E-04"},{"v":0.004456642,"d":"4.46E-03"},{"v":0.00173121,"d":"1.73E-03"},"TP53/STAT3",2,{"v":46.675,"d":"46.68"}]
["GO-BP","GO:0045637","regulation of myeloid cell differentiation",{"v":0.000853008,"d":"8.53E-04"},{"v":0.004553637,"d":"4.55E-03"},{"v":0.001768888,"d":"1.77E-03"},"MAPK14/STAT3/CREB1/NFKBIA",4,{"v":9.297808765,"d":"9.30"}]
["GO-BP","GO:0031330","negative regulation of cellular catabolic process",{"v":0.000878582,"d":"8.79E-04"},{"v":0.004680137,"d":"4.68E-03"},{"v":0.001818028,"d":"1.82E-03"},"MAPK14/TP53/STAT3/AKT1",4,{"v":9.2243083,"d":"9.22"}]
["GO-BP","GO:0022037","metencephalon development",{"v":0.000894714,"d":"8.95E-04"},{"v":0.004731487,"d":"4.73E-03"},{"v":0.001837975,"d":"1.84E-03"},"TP53/MAP2K1/PTPN11",3,{"v":15.76858108,"d":"15.77"}]
["GO-BP","GO:0007389","pattern specification process",{"v":0.00089934,"d":"8.99E-04"},{"v":0.004731487,"d":"4.73E-03"},{"v":0.001837975,"d":"1.84E-03"},"TP53/SMAD4/SMAD5/ATM/SMAD2",5,{"v":6.540779148,"d":"6.54"}]
["GO-BP","GO:1900739","regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway",{"v":0.000901507,"d":"9.02E-04"},{"v":0.004731487,"d":"4.73E-03"},{"v":0.001837975,"d":"1.84E-03"},"MAPK8/TP53",2,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:1900740","positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway",{"v":0.000901507,"d":"9.02E-04"},{"v":0.004731487,"d":"4.73E-03"},{"v":0.001837975,"d":"1.84E-03"},"MAPK8/TP53",2,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:1903579","negative regulation of ATP metabolic process",{"v":0.000901507,"d":"9.02E-04"},{"v":0.004731487,"d":"4.73E-03"},{"v":0.001837975,"d":"1.84E-03"},"TP53/STAT3",2,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:1904353","regulation of telomere capping",{"v":0.000901507,"d":"9.02E-04"},{"v":0.004731487,"d":"4.73E-03"},{"v":0.001837975,"d":"1.84E-03"},"MAPK1/ATM",2,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:1905048","regulation of metallopeptidase activity",{"v":0.000901507,"d":"9.02E-04"},{"v":0.004731487,"d":"4.73E-03"},{"v":0.001837975,"d":"1.84E-03"},"MAPK14/STAT3",2,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0022409","positive regulation of cell-cell adhesion",{"v":0.000904693,"d":"9.05E-04"},{"v":0.004738237,"d":"4.74E-03"},{"v":0.001840597,"d":"1.84E-03"},"PTPN6/PTPN11/ZAP70/AKT1",4,{"v":9.151960784,"d":"9.15"}]
["GO-BP","GO:0001938","positive regulation of endothelial cell proliferation",{"v":0.000918272,"d":"9.18E-04"},{"v":0.004789231,"d":"4.79E-03"},{"v":0.001860406,"d":"1.86E-03"},"STAT3/STAT5A/AKT1",3,{"v":15.62779018,"d":"15.63"}]
["GO-BP","GO:0008645","hexose transmembrane transport",{"v":0.000918272,"d":"9.18E-04"},{"v":0.004789231,"d":"4.79E-03"},{"v":0.001860406,"d":"1.86E-03"},"MAPK14/PTPN11/AKT1",3,{"v":15.62779018,"d":"15.63"}]
["GO-BP","GO:0046620","regulation of organ growth",{"v":0.000942221,"d":"9.42E-04"},{"v":0.004903877,"d":"4.90E-03"},{"v":0.001904941,"d":"1.90E-03"},"MAPK14/MAPK1/AKT1",3,{"v":15.48949115,"d":"15.49"}]
["GO-BP","GO:0006839","mitochondrial transport",{"v":0.000944883,"d":"9.45E-04"},{"v":0.004907488,"d":"4.91E-03"},{"v":0.001906344,"d":"1.91E-03"},"MAPK8/TP53/STAT3/PRKAA1",4,{"v":9.045542636,"d":"9.05"}]
["GO-BP","GO:0052547","regulation of peptidase activity",{"v":0.000954811,"d":"9.55E-04"},{"v":0.004948738,"d":"4.95E-03"},{"v":0.001922367,"d":"1.92E-03"},"MAPK14/RPS6KA1/STAT3/JAK2/AKT1",5,{"v":6.453954646,"d":"6.45"}]
["GO-BP","GO:0015749","monosaccharide transmembrane transport",{"v":0.000966564,"d":"9.67E-04"},{"v":0.004989009,"d":"4.99E-03"},{"v":0.001938011,"d":"1.94E-03"},"MAPK14/PTPN11/AKT1",3,{"v":15.35361842,"d":"15.35"}]
["GO-BP","GO:1902175","regulation of oxidative stress-induced intrinsic apoptotic signaling pathway",{"v":0.000972587,"d":"9.73E-04"},{"v":0.004989009,"d":"4.99E-03"},{"v":0.001938011,"d":"1.94E-03"},"HSPB1/AKT1",2,{"v":43.21759259,"d":"43.22"}]
["GO-BP","GO:1905208","negative regulation of cardiocyte differentiation",{"v":0.000972587,"d":"9.73E-04"},{"v":0.004989009,"d":"4.99E-03"},{"v":0.001938011,"d":"1.94E-03"},"SMAD4/EGFR",2,{"v":43.21759259,"d":"43.22"}]
["GO-BP","GO:2000144","positive regulation of DNA-templated transcription, initiation",{"v":0.000972587,"d":"9.73E-04"},{"v":0.004989009,"d":"4.99E-03"},{"v":0.001938011,"d":"1.94E-03"},"TP53/CREB1",2,{"v":43.21759259,"d":"43.22"}]
["GO-BP","GO:2000191","regulation of fatty acid transport",{"v":0.000972587,"d":"9.73E-04"},{"v":0.004989009,"d":"4.99E-03"},{"v":0.001938011,"d":"1.94E-03"},"MAP2K6/AKT1",2,{"v":43.21759259,"d":"43.22"}]
["GO-BP","GO:0051091","positive regulation of DNA-binding transcription factor activity",{"v":0.000986319,"d":"9.86E-04"},{"v":0.005049061,"d":"5.05E-03"},{"v":0.001961339,"d":"1.96E-03"},"RPS6KA4/STAT3/JAK2/AKT1",4,{"v":8.941570881,"d":"8.94"}]
["GO-BP","GO:0010822","positive regulation of mitochondrion organization",{"v":0.001016439,"d":"1.02E-03"},{"v":0.005171393,"d":"5.17E-03"},{"v":0.002008859,"d":"2.01E-03"},"MAPK8/TP53/PRKAA1",3,{"v":15.08890086,"d":"15.09"}]
["GO-BP","GO:0034219","carbohydrate transmembrane transport",{"v":0.001016439,"d":"1.02E-03"},{"v":0.005171393,"d":"5.17E-03"},{"v":0.002008859,"d":"2.01E-03"},"MAPK14/PTPN11/AKT1",3,{"v":15.08890086,"d":"15.09"}]
["GO-BP","GO:1900180","regulation of protein localization to nucleus",{"v":0.001016439,"d":"1.02E-03"},{"v":0.005171393,"d":"5.17E-03"},{"v":0.002008859,"d":"2.01E-03"},"MAPK14/MAPK1/AKT1",3,{"v":15.08890086,"d":"15.09"}]
["GO-BP","GO:0033598","mammary gland epithelial cell proliferation",{"v":0.001046282,"d":"1.05E-03"},{"v":0.005290831,"d":"5.29E-03"},{"v":0.002055256,"d":"2.06E-03"},"MAPK1/STAT6",2,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0051123","RNA polymerase II preinitiation complex assembly",{"v":0.001046282,"d":"1.05E-03"},{"v":0.005290831,"d":"5.29E-03"},{"v":0.002055256,"d":"2.06E-03"},"TP53/CREB1",2,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0060260","regulation of transcription initiation from RNA polymerase II promoter",{"v":0.001046282,"d":"1.05E-03"},{"v":0.005290831,"d":"5.29E-03"},{"v":0.002055256,"d":"2.06E-03"},"TP53/CREB1",2,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0001667","ameboidal-type cell migration",{"v":0.001052897,"d":"1.05E-03"},{"v":0.005313507,"d":"5.31E-03"},{"v":0.002064064,"d":"2.06E-03"},"HSPB1/MAP2K3/PTPN11/STAT5A/AKT1",5,{"v":6.314258658,"d":"6.31"}]
["GO-BP","GO:0050714","positive regulation of protein secretion",{"v":0.001087965,"d":"1.09E-03"},{"v":0.005479387,"d":"5.48E-03"},{"v":0.002128501,"d":"2.13E-03"},"MAPK14/JAK2/PSMD9/EGFR",4,{"v":8.708022388,"d":"8.71"}]
["GO-BP","GO:0007173","epidermal growth factor receptor signaling pathway",{"v":0.001094266,"d":"1.09E-03"},{"v":0.00550001,"d":"5.50E-03"},{"v":0.002136513,"d":"2.14E-03"},"PTPN11/AKT1/EGFR",3,{"v":14.7085084,"d":"14.71"}]
["GO-BP","GO:0007249","I-kappaB kinase/NF-kappaB signaling",{"v":0.001103065,"d":"1.10E-03"},{"v":0.005533079,"d":"5.53E-03"},{"v":0.002149358,"d":"2.15E-03"},"HSPB1/TBK1/NFKBIA/AKT1",4,{"v":8.675650558,"d":"8.68"}]
["GO-BP","GO:0007409","axonogenesis",{"v":0.001115248,"d":"1.12E-03"},{"v":0.005563815,"d":"5.56E-03"},{"v":0.002161298,"d":"2.16E-03"},"MAP2K1/SMAD4/PTPN11/MAPK1/CREB1",5,{"v":6.233306624,"d":"6.23"}]
["GO-BP","GO:0042326","negative regulation of phosphorylation",{"v":0.001115248,"d":"1.12E-03"},{"v":0.005563815,"d":"5.56E-03"},{"v":0.002161298,"d":"2.16E-03"},"PTPN6/HSPB1/SMAD4/STAT3/AKT1",5,{"v":6.233306624,"d":"6.23"}]
["GO-BP","GO:0007548","sex differentiation",{"v":0.001118311,"d":"1.12E-03"},{"v":0.005563815,"d":"5.56E-03"},{"v":0.002161298,"d":"2.16E-03"},"SMAD4/PTPN11/SMAD5/ATM",4,{"v":8.643518519,"d":"8.64"}]
["GO-BP","GO:0017015","regulation of transforming growth factor beta receptor signaling pathway",{"v":0.001121022,"d":"1.12E-03"},{"v":0.005563815,"d":"5.56E-03"},{"v":0.002161298,"d":"2.16E-03"},"TP53/SMAD4/SMAD2",3,{"v":14.5859375,"d":"14.59"}]
["GO-BP","GO:0022612","gland morphogenesis",{"v":0.001121022,"d":"1.12E-03"},{"v":0.005563815,"d":"5.56E-03"},{"v":0.002161298,"d":"2.16E-03"},"RPS6KA1/STAT6/EGFR",3,{"v":14.5859375,"d":"14.59"}]
["GO-BP","GO:0031063","regulation of histone deacetylation",{"v":0.001122583,"d":"1.12E-03"},{"v":0.005563815,"d":"5.56E-03"},{"v":0.002161298,"d":"2.16E-03"},"MAPK8/TP53",2,{"v":40.23706897,"d":"40.24"}]
["GO-BP","GO:1903578","regulation of ATP metabolic process",{"v":0.001148189,"d":"1.15E-03"},{"v":0.005673422,"d":"5.67E-03"},{"v":0.002203875,"d":"2.20E-03"},"TP53/STAT3/PRKAA1",3,{"v":14.46539256,"d":"14.47"}]
["GO-BP","GO:0032868","response to insulin",{"v":0.001149249,"d":"1.15E-03"},{"v":0.005673422,"d":"5.67E-03"},{"v":0.002203875,"d":"2.20E-03"},"PTPN11/EIF4EBP1/PRKAA1/AKT1",4,{"v":8.579963235,"d":"8.58"}]
["GO-BP","GO:0050708","regulation of protein secretion",{"v":0.001158318,"d":"1.16E-03"},{"v":0.005706892,"d":"5.71E-03"},{"v":0.002216877,"d":"2.22E-03"},"MAPK14/PTPN11/JAK2/PSMD9/EGFR",5,{"v":6.180481992,"d":"6.18"}]
["GO-BP","GO:0006260","DNA replication",{"v":0.001164942,"d":"1.16E-03"},{"v":0.005728205,"d":"5.73E-03"},{"v":0.002225156,"d":"2.23E-03"},"TP53/RBM14/ATM/EGFR",4,{"v":8.548534799,"d":"8.55"}]
["GO-BP","GO:1903409","reactive oxygen species biosynthetic process",{"v":0.001175769,"d":"1.18E-03"},{"v":0.005758729,"d":"5.76E-03"},{"v":0.002237013,"d":"2.24E-03"},"STAT3/JAK2/AKT1",3,{"v":14.34682377,"d":"14.35"}]
["GO-BP","GO:1903844","regulation of cellular response to transforming growth factor beta stimulus",{"v":0.001175769,"d":"1.18E-03"},{"v":0.005758729,"d":"5.76E-03"},{"v":0.002237013,"d":"2.24E-03"},"TP53/SMAD4/SMAD2",3,{"v":14.34682377,"d":"14.35"}]
["GO-BP","GO:0043542","endothelial cell migration",{"v":0.001180785,"d":"1.18E-03"},{"v":0.005771953,"d":"5.77E-03"},{"v":0.00224215,"d":"2.24E-03"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":8.517335766,"d":"8.52"}]
["GO-BP","GO:0001844","protein insertion into mitochondrial membrane involved in apoptotic signaling pathway",{"v":0.001201482,"d":"1.20E-03"},{"v":0.005793607,"d":"5.79E-03"},{"v":0.002250562,"d":"2.25E-03"},"MAPK8/TP53",2,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0021696","cerebellar cortex morphogenesis",{"v":0.001201482,"d":"1.20E-03"},{"v":0.005793607,"d":"5.79E-03"},{"v":0.002250562,"d":"2.25E-03"},"MAP2K1/PTPN11",2,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0032728","positive regulation of interferon-beta production",{"v":0.001201482,"d":"1.20E-03"},{"v":0.005793607,"d":"5.79E-03"},{"v":0.002250562,"d":"2.25E-03"},"PTPN11/TBK1",2,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0035066","positive regulation of histone acetylation",{"v":0.001201482,"d":"1.20E-03"},{"v":0.005793607,"d":"5.79E-03"},{"v":0.002250562,"d":"2.25E-03"},"SMAD4/RPS6KA4",2,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0038111","interleukin-7-mediated signaling pathway",{"v":0.001201482,"d":"1.20E-03"},{"v":0.005793607,"d":"5.79E-03"},{"v":0.002250562,"d":"2.25E-03"},"STAT3/STAT5A",2,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0071480","cellular response to gamma radiation",{"v":0.001201482,"d":"1.20E-03"},{"v":0.005793607,"d":"5.79E-03"},{"v":0.002250562,"d":"2.25E-03"},"TP53/ATM",2,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0071549","cellular response to dexamethasone stimulus",{"v":0.001201482,"d":"1.20E-03"},{"v":0.005793607,"d":"5.79E-03"},{"v":0.002250562,"d":"2.25E-03"},"EIF4EBP1/EGFR",2,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0008637","apoptotic mitochondrial changes",{"v":0.00123218,"d":"1.23E-03"},{"v":0.005918737,"d":"5.92E-03"},{"v":0.00229917,"d":"2.30E-03"},"MAPK8/TP53/AKT1",3,{"v":14.11542339,"d":"14.12"}]
["GO-BP","GO:0051101","regulation of DNA binding",{"v":0.00123218,"d":"1.23E-03"},{"v":0.005918737,"d":"5.92E-03"},{"v":0.00229917,"d":"2.30E-03"},"MAPK8/JAK2/NFKBIA",3,{"v":14.11542339,"d":"14.12"}]
["GO-BP","GO:0045471","response to ethanol",{"v":0.001261015,"d":"1.26E-03"},{"v":0.006045597,"d":"6.05E-03"},{"v":0.002348449,"d":"2.35E-03"},"STAT3/EIF4EBP1/PRKAA1",3,{"v":14.0025,"d":"14.00"}]
["GO-BP","GO:0010165","response to X-ray",{"v":0.001282971,"d":"1.28E-03"},{"v":0.006092277,"d":"6.09E-03"},{"v":0.002366582,"d":"2.37E-03"},"TP53/ATM",2,{"v":37.64112903,"d":"37.64"}]
["GO-BP","GO:0034694","response to prostaglandin",{"v":0.001282971,"d":"1.28E-03"},{"v":0.006092277,"d":"6.09E-03"},{"v":0.002366582,"d":"2.37E-03"},"PRKAA1/AKT1",2,{"v":37.64112903,"d":"37.64"}]
["GO-BP","GO:0045648","positive regulation of erythrocyte differentiation",{"v":0.001282971,"d":"1.28E-03"},{"v":0.006092277,"d":"6.09E-03"},{"v":0.002366582,"d":"2.37E-03"},"MAPK14/STAT3",2,{"v":37.64112903,"d":"37.64"}]
["GO-BP","GO:0045737","positive regulation of cyclin-dependent protein serine/threonine kinase activity",{"v":0.001282971,"d":"1.28E-03"},{"v":0.006092277,"d":"6.09E-03"},{"v":0.002366582,"d":"2.37E-03"},"AKT1/EGFR",2,{"v":37.64112903,"d":"37.64"}]
["GO-BP","GO:1902895","positive regulation of pri-miRNA transcription by RNA polymerase II",{"v":0.001282971,"d":"1.28E-03"},{"v":0.006092277,"d":"6.09E-03"},{"v":0.002366582,"d":"2.37E-03"},"TP53/STAT3",2,{"v":37.64112903,"d":"37.64"}]
["GO-BP","GO:0032479","regulation of type I interferon production",{"v":0.001290273,"d":"1.29E-03"},{"v":0.006115306,"d":"6.12E-03"},{"v":0.002375528,"d":"2.38E-03"},"PTPN11/STAT6/TBK1",3,{"v":13.89136905,"d":"13.89"}]
["GO-BP","GO:0016049","cell growth",{"v":0.001294982,"d":"1.29E-03"},{"v":0.006125976,"d":"6.13E-03"},{"v":0.002379673,"d":"2.38E-03"},"TP53/RPS6KA1/SMAD4/AKT1/EGFR",5,{"v":6.027246901,"d":"6.03"}]
["GO-BP","GO:0060047","heart contraction",{"v":0.00131303,"d":"1.31E-03"},{"v":0.006199589,"d":"6.20E-03"},{"v":0.002408268,"d":"2.41E-03"},"MAP2K3/SMAD5/MAP2K6/JAK2",4,{"v":8.27570922,"d":"8.28"}]
["GO-BP","GO:0043620","regulation of DNA-templated transcription in response to stress",{"v":0.001319957,"d":"1.32E-03"},{"v":0.006220514,"d":"6.22E-03"},{"v":0.002416397,"d":"2.42E-03"},"TP53/RPS6KA1/PSMD9",3,{"v":13.78198819,"d":"13.78"}]
["GO-BP","GO:0032606","type I interferon production",{"v":0.001350068,"d":"1.35E-03"},{"v":0.006350414,"d":"6.35E-03"},{"v":0.002466857,"d":"2.47E-03"},"PTPN11/STAT6/TBK1",3,{"v":13.67431641,"d":"13.67"}]
["GO-BP","GO:0051348","negative regulation of transferase activity",{"v":0.001365196,"d":"1.37E-03"},{"v":0.006406072,"d":"6.41E-03"},{"v":0.002488478,"d":"2.49E-03"},"PTPN6/TP53/HSPB1/AKT1",4,{"v":8.188596491,"d":"8.19"}]
["GO-BP","GO:0045907","positive regulation of vasoconstriction",{"v":0.00136704,"d":"1.37E-03"},{"v":0.006406072,"d":"6.41E-03"},{"v":0.002488478,"d":"2.49E-03"},"AKT1/EGFR",2,{"v":36.46484375,"d":"36.46"}]
["GO-BP","GO:0005996","monosaccharide metabolic process",{"v":0.00140077,"d":"1.40E-03"},{"v":0.006551818,"d":"6.55E-03"},{"v":0.002545094,"d":"2.55E-03"},"MAPK14/TP53/PRKAA1/AKT1",4,{"v":8.131533101,"d":"8.13"}]
["GO-BP","GO:0002793","positive regulation of peptide secretion",{"v":0.001418798,"d":"1.42E-03"},{"v":0.006623715,"d":"6.62E-03"},{"v":0.002573023,"d":"2.57E-03"},"MAPK14/JAK2/PSMD9/EGFR",4,{"v":8.103298611,"d":"8.10"}]
["GO-BP","GO:0007162","negative regulation of cell adhesion",{"v":0.001436989,"d":"1.44E-03"},{"v":0.006696099,"d":"6.70E-03"},{"v":0.002601141,"d":"2.60E-03"},"PTPN6/PTPN11/JAK2/AKT1",4,{"v":8.075259516,"d":"8.08"}]
["GO-BP","GO:0030183","B cell differentiation",{"v":0.001442992,"d":"1.44E-03"},{"v":0.006711528,"d":"6.71E-03"},{"v":0.002607134,"d":"2.61E-03"},"PTPN6/TP53/ATM",3,{"v":13.36116412,"d":"13.36"}]
["GO-BP","GO:0016242","negative regulation of macroautophagy",{"v":0.001453681,"d":"1.45E-03"},{"v":0.00673611,"d":"6.74E-03"},{"v":0.002616683,"d":"2.62E-03"},"TP53/AKT1",2,{"v":35.35984848,"d":"35.36"}]
["GO-BP","GO:0030513","positive regulation of BMP signaling pathway",{"v":0.001453681,"d":"1.45E-03"},{"v":0.00673611,"d":"6.74E-03"},{"v":0.002616683,"d":"2.62E-03"},"SMAD4/SMAD2",2,{"v":35.35984848,"d":"35.36"}]
["GO-BP","GO:0010632","regulation of epithelial cell migration",{"v":0.001473859,"d":"1.47E-03"},{"v":0.006808834,"d":"6.81E-03"},{"v":0.002644933,"d":"2.64E-03"},"HSPB1/MAP2K3/STAT5A/AKT1",4,{"v":8.01975945,"d":"8.02"}]
["GO-BP","GO:0045598","regulation of fat cell differentiation",{"v":0.001474838,"d":"1.47E-03"},{"v":0.006808834,"d":"6.81E-03"},{"v":0.002644933,"d":"2.64E-03"},"MAPK14/CREB1/AKT1",3,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0050900","leukocyte migration",{"v":0.001482252,"d":"1.48E-03"},{"v":0.006830415,"d":"6.83E-03"},{"v":0.002653316,"d":"2.65E-03"},"PTPN6/MAPK14/PTPN11/ZAP70/AKT1",5,{"v":5.846067134,"d":"5.85"}]
["GO-BP","GO:0003015","heart process",{"v":0.001492541,"d":"1.49E-03"},{"v":0.006852493,"d":"6.85E-03"},{"v":0.002661893,"d":"2.66E-03"},"MAP2K3/SMAD5/MAP2K6/JAK2",4,{"v":7.992294521,"d":"7.99"}]
["GO-BP","GO:0009410","response to xenobiotic stimulus",{"v":0.001492541,"d":"1.49E-03"},{"v":0.006852493,"d":"6.85E-03"},{"v":0.002661893,"d":"2.66E-03"},"STAT5A/EIF4EBP1/PRKAA1/EGFR",4,{"v":7.992294521,"d":"7.99"}]
["GO-BP","GO:0002791","regulation of peptide secretion",{"v":0.001495412,"d":"1.50E-03"},{"v":0.006853057,"d":"6.85E-03"},{"v":0.002662112,"d":"2.66E-03"},"MAPK14/PTPN11/JAK2/PSMD9/EGFR",5,{"v":5.834375,"d":"5.83"}]
["GO-BP","GO:0042770","signal transduction in response to DNA damage",{"v":0.001507123,"d":"1.51E-03"},{"v":0.00689405,"d":"6.89E-03"},{"v":0.002678036,"d":"2.68E-03"},"MAPK14/TP53/ATM",3,{"v":13.16024436,"d":"13.16"}]
["GO-BP","GO:0007006","mitochondrial membrane organization",{"v":0.001539849,"d":"1.54E-03"},{"v":0.006980791,"d":"6.98E-03"},{"v":0.002711731,"d":"2.71E-03"},"MAPK8/TP53/STAT3",3,{"v":13.06203358,"d":"13.06"}]
["GO-BP","GO:0032212","positive regulation of telomere maintenance via telomerase",{"v":0.001542886,"d":"1.54E-03"},{"v":0.006980791,"d":"6.98E-03"},{"v":0.002711731,"d":"2.71E-03"},"MAPK1/ATM",2,{"v":34.31985294,"d":"34.32"}]
["GO-BP","GO:0042533","tumor necrosis factor biosynthetic process",{"v":0.001542886,"d":"1.54E-03"},{"v":0.006980791,"d":"6.98E-03"},{"v":0.002711731,"d":"2.71E-03"},"HSPB1/JAK2",2,{"v":34.31985294,"d":"34.32"}]
["GO-BP","GO:0042534","regulation of tumor necrosis factor biosynthetic process",{"v":0.001542886,"d":"1.54E-03"},{"v":0.006980791,"d":"6.98E-03"},{"v":0.002711731,"d":"2.71E-03"},"HSPB1/JAK2",2,{"v":34.31985294,"d":"34.32"}]
["GO-BP","GO:0043516","regulation of DNA damage response, signal transduction by p53 class mediator",{"v":0.001542886,"d":"1.54E-03"},{"v":0.006980791,"d":"6.98E-03"},{"v":0.002711731,"d":"2.71E-03"},"TP53/ATM",2,{"v":34.31985294,"d":"34.32"}]
["GO-BP","GO:0097009","energy homeostasis",{"v":0.001542886,"d":"1.54E-03"},{"v":0.006980791,"d":"6.98E-03"},{"v":0.002711731,"d":"2.71E-03"},"STAT3/PRKAA1",2,{"v":34.31985294,"d":"34.32"}]
["GO-BP","GO:0007498","mesoderm development",{"v":0.00157302,"d":"1.57E-03"},{"v":0.007104237,"d":"7.10E-03"},{"v":0.002759684,"d":"2.76E-03"},"SMAD4/JAK2/SMAD2",3,{"v":12.96527778,"d":"12.97"}]
["GO-BP","GO:0090068","positive regulation of cell cycle process",{"v":0.001608125,"d":"1.61E-03"},{"v":0.007249647,"d":"7.25E-03"},{"v":0.00281617,"d":"2.82E-03"},"TP53/ATM/AKT1/EGFR",4,{"v":7.831375839,"d":"7.83"}]
["GO-BP","GO:0001893","maternal placenta development",{"v":0.001634647,"d":"1.63E-03"},{"v":0.007290116,"d":"7.29E-03"},{"v":0.00283189,"d":"2.83E-03"},"MAPK1/AKT1",2,{"v":33.33928571,"d":"33.34"}]
["GO-BP","GO:0010259","multicellular organism aging",{"v":0.001634647,"d":"1.63E-03"},{"v":0.007290116,"d":"7.29E-03"},{"v":0.00283189,"d":"2.83E-03"},"TP53/ATM",2,{"v":33.33928571,"d":"33.34"}]
["GO-BP","GO:0070423","nucleotide-binding oligomerization domain containing signaling pathway",{"v":0.001634647,"d":"1.63E-03"},{"v":0.007290116,"d":"7.29E-03"},{"v":0.00283189,"d":"2.83E-03"},"MAP2K6/NFKBIA",2,{"v":33.33928571,"d":"33.34"}]
["GO-BP","GO:0098751","bone cell development",{"v":0.001634647,"d":"1.63E-03"},{"v":0.007290116,"d":"7.29E-03"},{"v":0.00283189,"d":"2.83E-03"},"PTPN6/PTPN11",2,{"v":33.33928571,"d":"33.34"}]
["GO-BP","GO:1901030","positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway",{"v":0.001634647,"d":"1.63E-03"},{"v":0.007290116,"d":"7.29E-03"},{"v":0.00283189,"d":"2.83E-03"},"MAPK8/TP53",2,{"v":33.33928571,"d":"33.34"}]
["GO-BP","GO:1904031","positive regulation of cyclin-dependent protein kinase activity",{"v":0.001634647,"d":"1.63E-03"},{"v":0.007290116,"d":"7.29E-03"},{"v":0.00283189,"d":"2.83E-03"},"AKT1/EGFR",2,{"v":33.33928571,"d":"33.34"}]
["GO-BP","GO:0010675","regulation of cellular carbohydrate metabolic process",{"v":0.001640702,"d":"1.64E-03"},{"v":0.007291033,"d":"7.29E-03"},{"v":0.002832246,"d":"2.83E-03"},"TP53/STAT3/AKT1",3,{"v":12.77600365,"d":"12.78"}]
["GO-BP","GO:0034605","cellular response to heat",{"v":0.001640702,"d":"1.64E-03"},{"v":0.007291033,"d":"7.29E-03"},{"v":0.002832246,"d":"2.83E-03"},"MAPK1/EIF2S1/ATM",3,{"v":12.77600365,"d":"12.78"}]
["GO-BP","GO:0046631","alpha-beta T cell activation",{"v":0.001675217,"d":"1.68E-03"},{"v":0.007431168,"d":"7.43E-03"},{"v":0.002886683,"d":"2.89E-03"},"STAT3/ZAP70/STAT6",3,{"v":12.68342391,"d":"12.68"}]
["GO-BP","GO:0000578","embryonic axis specification",{"v":0.001728954,"d":"1.73E-03"},{"v":0.007605735,"d":"7.61E-03"},{"v":0.002954494,"d":"2.95E-03"},"SMAD4/SMAD2",2,{"v":32.41319444,"d":"32.41"}]
["GO-BP","GO:0035872","nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",{"v":0.001728954,"d":"1.73E-03"},{"v":0.007605735,"d":"7.61E-03"},{"v":0.002954494,"d":"2.95E-03"},"MAP2K6/NFKBIA",2,{"v":32.41319444,"d":"32.41"}]
["GO-BP","GO:0060428","lung epithelium development",{"v":0.001728954,"d":"1.73E-03"},{"v":0.007605735,"d":"7.61E-03"},{"v":0.002954494,"d":"2.95E-03"},"MAP2K1/CREB1",2,{"v":32.41319444,"d":"32.41"}]
["GO-BP","GO:0071634","regulation of transforming growth factor beta production",{"v":0.001728954,"d":"1.73E-03"},{"v":0.007605735,"d":"7.61E-03"},{"v":0.002954494,"d":"2.95E-03"},"SMAD4/CREB1",2,{"v":32.41319444,"d":"32.41"}]
["GO-BP","GO:1903037","regulation of leukocyte cell-cell adhesion",{"v":0.001729824,"d":"1.73E-03"},{"v":0.007605735,"d":"7.61E-03"},{"v":0.002954494,"d":"2.95E-03"},"PTPN6/PTPN11/ZAP70/AKT1",4,{"v":7.676809211,"d":"7.68"}]
["GO-BP","GO:0060048","cardiac muscle contraction",{"v":0.001745609,"d":"1.75E-03"},{"v":0.00764816,"d":"7.65E-03"},{"v":0.002970975,"d":"2.97E-03"},"MAP2K3/SMAD5/MAP2K6",3,{"v":12.50223214,"d":"12.50"}]
["GO-BP","GO:0072073","kidney epithelium development",{"v":0.001745609,"d":"1.75E-03"},{"v":0.00764816,"d":"7.65E-03"},{"v":0.002970975,"d":"2.97E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":12.50223214,"d":"12.50"}]
["GO-BP","GO:0062013","positive regulation of small molecule metabolic process",{"v":0.001781489,"d":"1.78E-03"},{"v":0.007791672,"d":"7.79E-03"},{"v":0.003026723,"d":"3.03E-03"},"STAT3/PRKAA1/AKT1",3,{"v":12.41356383,"d":"12.41"}]
["GO-BP","GO:0021587","cerebellum morphogenesis",{"v":0.0018258,"d":"1.83E-03"},{"v":0.007916032,"d":"7.92E-03"},{"v":0.003075031,"d":"3.08E-03"},"MAP2K1/PTPN11",2,{"v":31.53716216,"d":"31.54"}]
["GO-BP","GO:0042307","positive regulation of protein import into nucleus",{"v":0.0018258,"d":"1.83E-03"},{"v":0.007916032,"d":"7.92E-03"},{"v":0.003075031,"d":"3.08E-03"},"MAPK14/MAPK1",2,{"v":31.53716216,"d":"31.54"}]
["GO-BP","GO:0098926","postsynaptic signal transduction",{"v":0.0018258,"d":"1.83E-03"},{"v":0.007916032,"d":"7.92E-03"},{"v":0.003075031,"d":"3.08E-03"},"STAT3/JAK2",2,{"v":31.53716216,"d":"31.54"}]
["GO-BP","GO:1904358","positive regulation of telomere maintenance via telomere lengthening",{"v":0.0018258,"d":"1.83E-03"},{"v":0.007916032,"d":"7.92E-03"},{"v":0.003075031,"d":"3.08E-03"},"MAPK1/ATM",2,{"v":31.53716216,"d":"31.54"}]
["GO-BP","GO:2000142","regulation of DNA-templated transcription, initiation",{"v":0.0018258,"d":"1.83E-03"},{"v":0.007916032,"d":"7.92E-03"},{"v":0.003075031,"d":"3.08E-03"},"TP53/CREB1",2,{"v":31.53716216,"d":"31.54"}]
["GO-BP","GO:0106106","cold-induced thermogenesis",{"v":0.001854631,"d":"1.85E-03"},{"v":0.008013161,"d":"8.01E-03"},{"v":0.003112761,"d":"3.11E-03"},"MAP2K6/JAK2/STAT6",3,{"v":12.23994755,"d":"12.24"}]
["GO-BP","GO:0120161","regulation of cold-induced thermogenesis",{"v":0.001854631,"d":"1.85E-03"},{"v":0.008013161,"d":"8.01E-03"},{"v":0.003112761,"d":"3.11E-03"},"MAP2K6/JAK2/STAT6",3,{"v":12.23994755,"d":"12.24"}]
["GO-BP","GO:0045022","early endosome to late endosome transport",{"v":0.001925175,"d":"1.93E-03"},{"v":0.008232352,"d":"8.23E-03"},{"v":0.003197907,"d":"3.20E-03"},"MAP2K1/MAPK1",2,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:0046676","negative regulation of insulin secretion",{"v":0.001925175,"d":"1.93E-03"},{"v":0.008232352,"d":"8.23E-03"},{"v":0.003197907,"d":"3.20E-03"},"PTPN11/PSMD9",2,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:0046825","regulation of protein export from nucleus",{"v":0.001925175,"d":"1.93E-03"},{"v":0.008232352,"d":"8.23E-03"},{"v":0.003197907,"d":"3.20E-03"},"TP53/PTPN11",2,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:0060045","positive regulation of cardiac muscle cell proliferation",{"v":0.001925175,"d":"1.93E-03"},{"v":0.008232352,"d":"8.23E-03"},{"v":0.003197907,"d":"3.20E-03"},"MAPK14/MAPK1",2,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:0071604","transforming growth factor beta production",{"v":0.001925175,"d":"1.93E-03"},{"v":0.008232352,"d":"8.23E-03"},{"v":0.003197907,"d":"3.20E-03"},"SMAD4/CREB1",2,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:1904037","positive regulation of epithelial cell apoptotic process",{"v":0.001925175,"d":"1.93E-03"},{"v":0.008232352,"d":"8.23E-03"},{"v":0.003197907,"d":"3.20E-03"},"EIF2S1/JAK2",2,{"v":30.70723684,"d":"30.71"}]
["GO-BP","GO:0071901","negative regulation of protein serine/threonine kinase activity",{"v":0.001929626,"d":"1.93E-03"},{"v":0.008237256,"d":"8.24E-03"},{"v":0.003199812,"d":"3.20E-03"},"PTPN6/HSPB1/AKT1",3,{"v":12.07112069,"d":"12.07"}]
["GO-BP","GO:0050863","regulation of T cell activation",{"v":0.001946705,"d":"1.95E-03"},{"v":0.008295959,"d":"8.30E-03"},{"v":0.003222616,"d":"3.22E-03"},"PTPN6/PTPN11/ZAP70/AKT1",4,{"v":7.432324841,"d":"7.43"}]
["GO-BP","GO:0045834","positive regulation of lipid metabolic process",{"v":0.001967824,"d":"1.97E-03"},{"v":0.008371648,"d":"8.37E-03"},{"v":0.003252018,"d":"3.25E-03"},"CREB1/PRKAA1/AKT1",3,{"v":11.98844178,"d":"11.99"}]
["GO-BP","GO:0050851","antigen receptor-mediated signaling pathway",{"v":0.001992245,"d":"1.99E-03"},{"v":0.0084611,"d":"8.46E-03"},{"v":0.003286766,"d":"3.29E-03"},"PTPN6/MAPK1/ZAP70/PSMD9",4,{"v":7.38528481,"d":"7.39"}]
["GO-BP","GO:0071236","cellular response to antibiotic",{"v":0.002006492,"d":"2.01E-03"},{"v":0.008507118,"d":"8.51E-03"},{"v":0.003304642,"d":"3.30E-03"},"TP53/STAT6/PRKAA1",3,{"v":11.90688776,"d":"11.91"}]
["GO-BP","GO:1902116","negative regulation of organelle assembly",{"v":0.002027072,"d":"2.03E-03"},{"v":0.008565238,"d":"8.57E-03"},{"v":0.003327219,"d":"3.33E-03"},"RBM14/SMAD4",2,{"v":29.91987179,"d":"29.92"}]
["GO-BP","GO:1904591","positive regulation of protein import",{"v":0.002027072,"d":"2.03E-03"},{"v":0.008565238,"d":"8.57E-03"},{"v":0.003327219,"d":"3.33E-03"},"MAPK14/MAPK1",2,{"v":29.91987179,"d":"29.92"}]
["GO-BP","GO:0008643","carbohydrate transport",{"v":0.002045633,"d":"2.05E-03"},{"v":0.008629039,"d":"8.63E-03"},{"v":0.003352003,"d":"3.35E-03"},"MAPK14/PTPN11/AKT1",3,{"v":11.82643581,"d":"11.83"}]
["GO-BP","GO:0071548","response to dexamethasone",{"v":0.002131482,"d":"2.13E-03"},{"v":0.008945765,"d":"8.95E-03"},{"v":0.003475037,"d":"3.48E-03"},"EIF4EBP1/EGFR",2,{"v":29.171875,"d":"29.17"}]
["GO-BP","GO:0098760","response to interleukin-7",{"v":0.002131482,"d":"2.13E-03"},{"v":0.008945765,"d":"8.95E-03"},{"v":0.003475037,"d":"3.48E-03"},"STAT3/STAT5A",2,{"v":29.171875,"d":"29.17"}]
["GO-BP","GO:0098761","cellular response to interleukin-7",{"v":0.002131482,"d":"2.13E-03"},{"v":0.008945765,"d":"8.95E-03"},{"v":0.003475037,"d":"3.48E-03"},"STAT3/STAT5A",2,{"v":29.171875,"d":"29.17"}]
["GO-BP","GO:1903311","regulation of mRNA metabolic process",{"v":0.002181821,"d":"2.18E-03"},{"v":0.009141647,"d":"9.14E-03"},{"v":0.003551129,"d":"3.55E-03"},"MAPK14/HSPB1/AKT1/PSMD9",4,{"v":7.202932099,"d":"7.20"}]
["GO-BP","GO:0030902","hindbrain development",{"v":0.002206954,"d":"2.21E-03"},{"v":0.009215975,"d":"9.22E-03"},{"v":0.003580002,"d":"3.58E-03"},"TP53/MAP2K1/PTPN11",3,{"v":11.51521382,"d":"11.52"}]
["GO-BP","GO:0032675","regulation of interleukin-6 production",{"v":0.002206954,"d":"2.21E-03"},{"v":0.009215975,"d":"9.22E-03"},{"v":0.003580002,"d":"3.58E-03"},"PTPN6/PTPN11/STAT3",3,{"v":11.51521382,"d":"11.52"}]
["GO-BP","GO:0021575","hindbrain morphogenesis",{"v":0.002238397,"d":"2.24E-03"},{"v":0.009285063,"d":"9.29E-03"},{"v":0.003606839,"d":"3.61E-03"},"MAP2K1/PTPN11",2,{"v":28.46036585,"d":"28.46"}]
["GO-BP","GO:0098927","vesicle-mediated transport between endosomal compartments",{"v":0.002238397,"d":"2.24E-03"},{"v":0.009285063,"d":"9.29E-03"},{"v":0.003606839,"d":"3.61E-03"},"MAP2K1/MAPK1",2,{"v":28.46036585,"d":"28.46"}]
["GO-BP","GO:0140353","lipid export from cell",{"v":0.002238397,"d":"2.24E-03"},{"v":0.009285063,"d":"9.29E-03"},{"v":0.003606839,"d":"3.61E-03"},"PTPN11/MAP2K6",2,{"v":28.46036585,"d":"28.46"}]
["GO-BP","GO:1902893","regulation of pri-miRNA transcription by RNA polymerase II",{"v":0.002238397,"d":"2.24E-03"},{"v":0.009285063,"d":"9.29E-03"},{"v":0.003606839,"d":"3.61E-03"},"TP53/STAT3",2,{"v":28.46036585,"d":"28.46"}]
["GO-BP","GO:0050729","positive regulation of inflammatory response",{"v":0.002248485,"d":"2.25E-03"},{"v":0.009311418,"d":"9.31E-03"},{"v":0.003617077,"d":"3.62E-03"},"JAK2/NFKBIA/EGFR",3,{"v":11.43995098,"d":"11.44"}]
["GO-BP","GO:1990845","adaptive thermogenesis",{"v":0.0022905,"d":"2.29E-03"},{"v":0.00946968,"d":"9.47E-03"},{"v":0.003678555,"d":"3.68E-03"},"MAP2K6/JAK2/STAT6",3,{"v":11.36566558,"d":"11.37"}]
["GO-BP","GO:0042149","cellular response to glucose starvation",{"v":0.002347808,"d":"2.35E-03"},{"v":0.009690538,"d":"9.69E-03"},{"v":0.003764348,"d":"3.76E-03"},"TP53/PRKAA1",2,{"v":27.7827381,"d":"27.78"}]
["GO-BP","GO:0019827","stem cell population maintenance",{"v":0.00241947,"d":"2.42E-03"},{"v":0.009953364,"d":"9.95E-03"},{"v":0.003866445,"d":"3.87E-03"},"SMAD4/STAT3/SMAD2",3,{"v":11.14848726,"d":"11.15"}]
["GO-BP","GO:0030509","BMP signaling pathway",{"v":0.00241947,"d":"2.42E-03"},{"v":0.009953364,"d":"9.95E-03"},{"v":0.003866445,"d":"3.87E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":11.14848726,"d":"11.15"}]
["GO-BP","GO:0031279","regulation of cyclase activity",{"v":0.002459707,"d":"2.46E-03"},{"v":0.010085608,"d":"1.01E-02"},{"v":0.003917816,"d":"3.92E-03"},"MAPK14/MAPK8",2,{"v":27.13662791,"d":"27.14"}]
["GO-BP","GO:0045429","positive regulation of nitric oxide biosynthetic process",{"v":0.002459707,"d":"2.46E-03"},{"v":0.010085608,"d":"1.01E-02"},{"v":0.003917816,"d":"3.92E-03"},"JAK2/AKT1",2,{"v":27.13662791,"d":"27.14"}]
["GO-BP","GO:0098727","maintenance of cell number",{"v":0.002507907,"d":"2.51E-03"},{"v":0.010266358,"d":"1.03E-02"},{"v":0.003988029,"d":"3.99E-03"},"SMAD4/STAT3/SMAD2",3,{"v":11.00825472,"d":"11.01"}]
["GO-BP","GO:0007159","leukocyte cell-cell adhesion",{"v":0.002516005,"d":"2.52E-03"},{"v":0.010282624,"d":"1.03E-02"},{"v":0.003994348,"d":"3.99E-03"},"PTPN6/PTPN11/ZAP70/AKT1",4,{"v":6.925074184,"d":"6.93"}]
["GO-BP","GO:0045930","negative regulation of mitotic cell cycle",{"v":0.002543091,"d":"2.54E-03"},{"v":0.010376309,"d":"1.04E-02"},{"v":0.004030741,"d":"4.03E-03"},"TP53/ATM/PSMD9/EGFR",4,{"v":6.904585799,"d":"6.90"}]
["GO-BP","GO:0044060","regulation of endocrine process",{"v":0.002574086,"d":"2.57E-03"},{"v":0.010434465,"d":"1.04E-02"},{"v":0.004053332,"d":"4.05E-03"},"SMAD4/PTPN11",2,{"v":26.51988636,"d":"26.52"}]
["GO-BP","GO:0070897","transcription preinitiation complex assembly",{"v":0.002574086,"d":"2.57E-03"},{"v":0.010434465,"d":"1.04E-02"},{"v":0.004053332,"d":"4.05E-03"},"TP53/CREB1",2,{"v":26.51988636,"d":"26.52"}]
["GO-BP","GO:1901028","regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway",{"v":0.002574086,"d":"2.57E-03"},{"v":0.010434465,"d":"1.04E-02"},{"v":0.004053332,"d":"4.05E-03"},"MAPK8/TP53",2,{"v":26.51988636,"d":"26.52"}]
["GO-BP","GO:1904407","positive regulation of nitric oxide metabolic process",{"v":0.002574086,"d":"2.57E-03"},{"v":0.010434465,"d":"1.04E-02"},{"v":0.004053332,"d":"4.05E-03"},"JAK2/AKT1",2,{"v":26.51988636,"d":"26.52"}]
["GO-BP","GO:0032635","interleukin-6 production",{"v":0.002598327,"d":"2.60E-03"},{"v":0.010515633,"d":"1.05E-02"},{"v":0.004084862,"d":"4.08E-03"},"PTPN6/PTPN11/STAT3",3,{"v":10.87150621,"d":"10.87"}]
["GO-BP","GO:0051204","protein insertion into mitochondrial membrane",{"v":0.002690936,"d":"2.69E-03"},{"v":0.010855185,"d":"1.09E-02"},{"v":0.004216763,"d":"4.22E-03"},"MAPK8/TP53",2,{"v":25.93055556,"d":"25.93"}]
["GO-BP","GO:0090278","negative regulation of peptide hormone secretion",{"v":0.002690936,"d":"2.69E-03"},{"v":0.010855185,"d":"1.09E-02"},{"v":0.004216763,"d":"4.22E-03"},"PTPN11/PSMD9",2,{"v":25.93055556,"d":"25.93"}]
["GO-BP","GO:2001242","regulation of intrinsic apoptotic signaling pathway",{"v":0.002785179,"d":"2.79E-03"},{"v":0.011209525,"d":"1.12E-02"},{"v":0.004354408,"d":"4.35E-03"},"TP53/HSPB1/AKT1",3,{"v":10.60795455,"d":"10.61"}]
["GO-BP","GO:0006984","ER-nucleus signaling pathway",{"v":0.00281025,"d":"2.81E-03"},{"v":0.011209525,"d":"1.12E-02"},{"v":0.004354408,"d":"4.35E-03"},"TP53/EIF2S1",2,{"v":25.36684783,"d":"25.37"}]
["GO-BP","GO:0032369","negative regulation of lipid transport",{"v":0.00281025,"d":"2.81E-03"},{"v":0.011209525,"d":"1.12E-02"},{"v":0.004354408,"d":"4.35E-03"},"PTPN11/AKT1",2,{"v":25.36684783,"d":"25.37"}]
["GO-BP","GO:0033628","regulation of cell adhesion mediated by integrin",{"v":0.00281025,"d":"2.81E-03"},{"v":0.011209525,"d":"1.12E-02"},{"v":0.004354408,"d":"4.35E-03"},"PTPN6/PTPN11",2,{"v":25.36684783,"d":"25.37"}]
["GO-BP","GO:0043330","response to exogenous dsRNA",{"v":0.00281025,"d":"2.81E-03"},{"v":0.011209525,"d":"1.12E-02"},{"v":0.004354408,"d":"4.35E-03"},"MAPK1/NFKBIA",2,{"v":25.36684783,"d":"25.37"}]
["GO-BP","GO:0045981","positive regulation of nucleotide metabolic process",{"v":0.00281025,"d":"2.81E-03"},{"v":0.011209525,"d":"1.12E-02"},{"v":0.004354408,"d":"4.35E-03"},"STAT3/PRKAA1",2,{"v":25.36684783,"d":"25.37"}]
["GO-BP","GO:1900544","positive regulation of purine nucleotide metabolic process",{"v":0.00281025,"d":"2.81E-03"},{"v":0.011209525,"d":"1.12E-02"},{"v":0.004354408,"d":"4.35E-03"},"STAT3/PRKAA1",2,{"v":25.36684783,"d":"25.37"}]
["GO-BP","GO:0002244","hematopoietic progenitor cell differentiation",{"v":0.002833155,"d":"2.83E-03"},{"v":0.011282838,"d":"1.13E-02"},{"v":0.004382887,"d":"4.38E-03"},"PTPN6/TP53/PSMD9",3,{"v":10.5440512,"d":"10.54"}]
["GO-BP","GO:0033209","tumor necrosis factor-mediated signaling pathway",{"v":0.002881641,"d":"2.88E-03"},{"v":0.011439379,"d":"1.14E-02"},{"v":0.004443696,"d":"4.44E-03"},"JAK2/NFKBIA/PSMD9",3,{"v":10.48091317,"d":"10.48"}]
["GO-BP","GO:0035051","cardiocyte differentiation",{"v":0.002881641,"d":"2.88E-03"},{"v":0.011439379,"d":"1.14E-02"},{"v":0.004443696,"d":"4.44E-03"},"SMAD4/MAPK1/EGFR",3,{"v":10.48091317,"d":"10.48"}]
["GO-BP","GO:0003002","regionalization",{"v":0.002913752,"d":"2.91E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"TP53/SMAD4/ATM/SMAD2",4,{"v":6.648860399,"d":"6.65"}]
["GO-BP","GO:0050806","positive regulation of synaptic transmission",{"v":0.002930636,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"MAPK1/CREB1/EGFR",3,{"v":10.41852679,"d":"10.42"}]
["GO-BP","GO:0021695","cerebellar cortex development",{"v":0.002932019,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"MAP2K1/PTPN11",2,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:0035722","interleukin-12-mediated signaling pathway",{"v":0.002932019,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"TYK2/JAK2",2,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:0045646","regulation of erythrocyte differentiation",{"v":0.002932019,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"MAPK14/STAT3",2,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:0060986","endocrine hormone secretion",{"v":0.002932019,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"SMAD4/PTPN11",2,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:0070231","T cell apoptotic process",{"v":0.002932019,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"TP53/AKT1",2,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:0090151","establishment of protein localization to mitochondrial membrane",{"v":0.002932019,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"MAPK8/TP53",2,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:1903580","positive regulation of ATP metabolic process",{"v":0.002932019,"d":"2.93E-03"},{"v":0.011474917,"d":"1.15E-02"},{"v":0.004457501,"d":"4.46E-03"},"STAT3/PRKAA1",2,{"v":24.82712766,"d":"24.83"}]
["GO-BP","GO:0018394","peptidyl-lysine acetylation",{"v":0.002980145,"d":"2.98E-03"},{"v":0.011590486,"d":"1.16E-02"},{"v":0.004502395,"d":"4.50E-03"},"SMAD4/RPS6KA4/PRKAA1",3,{"v":10.3568787,"d":"10.36"}]
["GO-BP","GO:0030307","positive regulation of cell growth",{"v":0.002980145,"d":"2.98E-03"},{"v":0.011590486,"d":"1.16E-02"},{"v":0.004502395,"d":"4.50E-03"},"RPS6KA1/AKT1/EGFR",3,{"v":10.3568787,"d":"10.36"}]
["GO-BP","GO:0038095","Fc-epsilon receptor signaling pathway",{"v":0.002980145,"d":"2.98E-03"},{"v":0.011590486,"d":"1.16E-02"},{"v":0.004502395,"d":"4.50E-03"},"MAPK8/MAPK1/PSMD9",3,{"v":10.3568787,"d":"10.36"}]
["GO-BP","GO:0048660","regulation of smooth muscle cell proliferation",{"v":0.002980145,"d":"2.98E-03"},{"v":0.011590486,"d":"1.16E-02"},{"v":0.004502395,"d":"4.50E-03"},"JAK2/AKT1/EGFR",3,{"v":10.3568787,"d":"10.36"}]
["GO-BP","GO:0071772","response to BMP",{"v":0.003030168,"d":"3.03E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":10.29595588,"d":"10.30"}]
["GO-BP","GO:0071773","cellular response to BMP stimulus",{"v":0.003030168,"d":"3.03E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"SMAD4/SMAD5/SMAD2",3,{"v":10.29595588,"d":"10.30"}]
["GO-BP","GO:0001774","microglial cell activation",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"ATM/JAK2",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0002269","leukocyte activation involved in inflammatory response",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"ATM/JAK2",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0007595","lactation",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"CREB1/STAT5A",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0032648","regulation of interferon-beta production",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"PTPN11/TBK1",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0045912","negative regulation of carbohydrate metabolic process",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"TP53/STAT3",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0051972","regulation of telomerase activity",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"TP53/MAPK1",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0055023","positive regulation of cardiac muscle tissue growth",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"MAPK14/MAPK1",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0090199","regulation of release of cytochrome c from mitochondria",{"v":0.003056234,"d":"3.06E-03"},{"v":0.011703826,"d":"1.17E-02"},{"v":0.004546423,"d":"4.55E-03"},"TP53/AKT1",2,{"v":24.30989583,"d":"24.31"}]
["GO-BP","GO:0048659","smooth muscle cell proliferation",{"v":0.003080707,"d":"3.08E-03"},{"v":0.011779452,"d":"1.18E-02"},{"v":0.0045758,"d":"4.58E-03"},"JAK2/AKT1/EGFR",3,{"v":10.23574561,"d":"10.24"}]
["GO-BP","GO:0045862","positive regulation of proteolysis",{"v":0.003127977,"d":"3.13E-03"},{"v":0.01194188,"d":"1.19E-02"},{"v":0.004638896,"d":"4.64E-03"},"MAPK14/STAT3/JAK2/AKT1",4,{"v":6.518854749,"d":"6.52"}]
["GO-BP","GO:0035094","response to nicotine",{"v":0.003182888,"d":"3.18E-03"},{"v":0.012059177,"d":"1.21E-02"},{"v":0.004684461,"d":"4.68E-03"},"MAPK1/CREB1",2,{"v":23.81377551,"d":"23.81"}]
["GO-BP","GO:0048546","digestive tract morphogenesis",{"v":0.003182888,"d":"3.18E-03"},{"v":0.012059177,"d":"1.21E-02"},{"v":0.004684461,"d":"4.68E-03"},"SMAD2/EGFR",2,{"v":23.81377551,"d":"23.81"}]
["GO-BP","GO:0061912","selective autophagy",{"v":0.003182888,"d":"3.18E-03"},{"v":0.012059177,"d":"1.21E-02"},{"v":0.004684461,"d":"4.68E-03"},"TP53/TBK1",2,{"v":23.81377551,"d":"23.81"}]
["GO-BP","GO:0071349","cellular response to interleukin-12",{"v":0.003182888,"d":"3.18E-03"},{"v":0.012059177,"d":"1.21E-02"},{"v":0.004684461,"d":"4.68E-03"},"TYK2/JAK2",2,{"v":23.81377551,"d":"23.81"}]
["GO-BP","GO:1990090","cellular response to nerve growth factor stimulus",{"v":0.003182888,"d":"3.18E-03"},{"v":0.012059177,"d":"1.21E-02"},{"v":0.004684461,"d":"4.68E-03"},"CREB1/AKT1",2,{"v":23.81377551,"d":"23.81"}]
["GO-BP","GO:0010948","negative regulation of cell cycle process",{"v":0.003223011,"d":"3.22E-03"},{"v":0.012192667,"d":"1.22E-02"},{"v":0.004736316,"d":"4.74E-03"},"TP53/RBM14/ATM/PSMD9",4,{"v":6.46468144,"d":"6.46"}]
["GO-BP","GO:0031331","positive regulation of cellular catabolic process",{"v":0.003255125,"d":"3.26E-03"},{"v":0.012295494,"d":"1.23E-02"},{"v":0.00477626,"d":"4.78E-03"},"ATM/TBK1/PRKAA1/AKT1",4,{"v":6.446823204,"d":"6.45"}]
["GO-BP","GO:0009409","response to cold",{"v":0.003311972,"d":"3.31E-03"},{"v":0.012397516,"d":"1.24E-02"},{"v":0.004815891,"d":"4.82E-03"},"NFKBIA/PRKAA1",2,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:0010718","positive regulation of epithelial to mesenchymal transition",{"v":0.003311972,"d":"3.31E-03"},{"v":0.012397516,"d":"1.24E-02"},{"v":0.004815891,"d":"4.82E-03"},"SMAD4/SMAD2",2,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:0032608","interferon-beta production",{"v":0.003311972,"d":"3.31E-03"},{"v":0.012397516,"d":"1.24E-02"},{"v":0.004815891,"d":"4.82E-03"},"PTPN11/TBK1",2,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:0060425","lung morphogenesis",{"v":0.003311972,"d":"3.31E-03"},{"v":0.012397516,"d":"1.24E-02"},{"v":0.004815891,"d":"4.82E-03"},"MAP2K1/MAPK1",2,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:0070671","response to interleukin-12",{"v":0.003311972,"d":"3.31E-03"},{"v":0.012397516,"d":"1.24E-02"},{"v":0.004815891,"d":"4.82E-03"},"TYK2/JAK2",2,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:1900087","positive regulation of G1/S transition of mitotic cell cycle",{"v":0.003311972,"d":"3.31E-03"},{"v":0.012397516,"d":"1.24E-02"},{"v":0.004815891,"d":"4.82E-03"},"AKT1/EGFR",2,{"v":23.3375,"d":"23.34"}]
["GO-BP","GO:0001936","regulation of endothelial cell proliferation",{"v":0.003341206,"d":"3.34E-03"},{"v":0.012469503,"d":"1.25E-02"},{"v":0.004843854,"d":"4.84E-03"},"STAT3/STAT5A/AKT1",3,{"v":9.944957386,"d":"9.94"}]
["GO-BP","GO:0050796","regulation of insulin secretion",{"v":0.003341206,"d":"3.34E-03"},{"v":0.012469503,"d":"1.25E-02"},{"v":0.004843854,"d":"4.84E-03"},"PTPN11/JAK2/PSMD9",3,{"v":9.944957386,"d":"9.94"}]
["GO-BP","GO:0006941","striated muscle contraction",{"v":0.003394879,"d":"3.39E-03"},{"v":0.012650873,"d":"1.27E-02"},{"v":0.004914309,"d":"4.91E-03"},"MAP2K3/SMAD5/MAP2K6",3,{"v":9.888771186,"d":"9.89"}]
["GO-BP","GO:0002712","regulation of B cell mediated immunity",{"v":0.003443478,"d":"3.44E-03"},{"v":0.012717912,"d":"1.27E-02"},{"v":0.00494035,"d":"4.94E-03"},"PTPN6/STAT6",2,{"v":22.87990196,"d":"22.88"}]
["GO-BP","GO:0002889","regulation of immunoglobulin mediated immune response",{"v":0.003443478,"d":"3.44E-03"},{"v":0.012717912,"d":"1.27E-02"},{"v":0.00494035,"d":"4.94E-03"},"PTPN6/STAT6",2,{"v":22.87990196,"d":"22.88"}]
["GO-BP","GO:0031103","axon regeneration",{"v":0.003443478,"d":"3.44E-03"},{"v":0.012717912,"d":"1.27E-02"},{"v":0.00494035,"d":"4.94E-03"},"MAP2K1/JAK2",2,{"v":22.87990196,"d":"22.88"}]
["GO-BP","GO:0032007","negative regulation of TOR signaling",{"v":0.003443478,"d":"3.44E-03"},{"v":0.012717912,"d":"1.27E-02"},{"v":0.00494035,"d":"4.94E-03"},"ATM/PRKAA1",2,{"v":22.87990196,"d":"22.88"}]
["GO-BP","GO:0032206","positive regulation of telomere maintenance",{"v":0.003443478,"d":"3.44E-03"},{"v":0.012717912,"d":"1.27E-02"},{"v":0.00494035,"d":"4.94E-03"},"MAPK1/ATM",2,{"v":22.87990196,"d":"22.88"}]
["GO-BP","GO:0050999","regulation of nitric-oxide synthase activity",{"v":0.003443478,"d":"3.44E-03"},{"v":0.012717912,"d":"1.27E-02"},{"v":0.00494035,"d":"4.94E-03"},"AKT1/EGFR",2,{"v":22.87990196,"d":"22.88"}]
["GO-BP","GO:0071347","cellular response to interleukin-1",{"v":0.003503811,"d":"3.50E-03"},{"v":0.012902513,"d":"1.29E-02"},{"v":0.00501206,"d":"5.01E-03"},"RPS6KA4/NFKBIA/PSMD9",3,{"v":9.778282123,"d":"9.78"}]
["GO-BP","GO:2001235","positive regulation of apoptotic signaling pathway",{"v":0.003503811,"d":"3.50E-03"},{"v":0.012902513,"d":"1.29E-02"},{"v":0.00501206,"d":"5.01E-03"},"MAPK8/TP53/JAK2",3,{"v":9.778282123,"d":"9.78"}]
["GO-BP","GO:0022408","negative regulation of cell-cell adhesion",{"v":0.003559074,"d":"3.56E-03"},{"v":0.013057765,"d":"1.31E-02"},{"v":0.005072369,"d":"5.07E-03"},"PTPN6/JAK2/AKT1",3,{"v":9.723958333,"d":"9.72"}]
["GO-BP","GO:0071466","cellular response to xenobiotic stimulus",{"v":0.003559074,"d":"3.56E-03"},{"v":0.013057765,"d":"1.31E-02"},{"v":0.005072369,"d":"5.07E-03"},"STAT5A/EIF4EBP1/EGFR",3,{"v":9.723958333,"d":"9.72"}]
["GO-BP","GO:0032731","positive regulation of interleukin-1 beta production",{"v":0.003577398,"d":"3.58E-03"},{"v":0.013057765,"d":"1.31E-02"},{"v":0.005072369,"d":"5.07E-03"},"HSPB1/JAK2",2,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:0060421","positive regulation of heart growth",{"v":0.003577398,"d":"3.58E-03"},{"v":0.013057765,"d":"1.31E-02"},{"v":0.005072369,"d":"5.07E-03"},"MAPK14/MAPK1",2,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:0072132","mesenchyme morphogenesis",{"v":0.003577398,"d":"3.58E-03"},{"v":0.013057765,"d":"1.31E-02"},{"v":0.005072369,"d":"5.07E-03"},"SMAD4/SMAD2",2,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:1990089","response to nerve growth factor",{"v":0.003577398,"d":"3.58E-03"},{"v":0.013057765,"d":"1.31E-02"},{"v":0.005072369,"d":"5.07E-03"},"CREB1/AKT1",2,{"v":22.43990385,"d":"22.44"}]
["GO-BP","GO:0002285","lymphocyte activation involved in immune response",{"v":0.00361487,"d":"3.61E-03"},{"v":0.013175249,"d":"1.32E-02"},{"v":0.005118006,"d":"5.12E-03"},"TP53/STAT3/STAT6",3,{"v":9.670234807,"d":"9.67"}]
["GO-BP","GO:0010823","negative regulation of mitochondrion organization",{"v":0.003713724,"d":"3.71E-03"},{"v":0.013456853,"d":"1.35E-02"},{"v":0.005227397,"d":"5.23E-03"},"TP53/AKT1",2,{"v":22.01650943,"d":"22.02"}]
["GO-BP","GO:0035065","regulation of histone acetylation",{"v":0.003713724,"d":"3.71E-03"},{"v":0.013456853,"d":"1.35E-02"},{"v":0.005227397,"d":"5.23E-03"},"SMAD4/RPS6KA4",2,{"v":22.01650943,"d":"22.02"}]
["GO-BP","GO:0038066","p38MAPK cascade",{"v":0.003713724,"d":"3.71E-03"},{"v":0.013456853,"d":"1.35E-02"},{"v":0.005227397,"d":"5.23E-03"},"MAPK14/MAP2K3",2,{"v":22.01650943,"d":"22.02"}]
["GO-BP","GO:0043331","response to dsRNA",{"v":0.003713724,"d":"3.71E-03"},{"v":0.013456853,"d":"1.35E-02"},{"v":0.005227397,"d":"5.23E-03"},"MAPK1/NFKBIA",2,{"v":22.01650943,"d":"22.02"}]
["GO-BP","GO:0042098","T cell proliferation",{"v":0.003785474,"d":"3.79E-03"},{"v":0.013657287,"d":"1.37E-02"},{"v":0.005305257,"d":"5.31E-03"},"PTPN6/TP53/ZAP70",3,{"v":9.512567935,"d":"9.51"}]
["GO-BP","GO:0043409","negative regulation of MAPK cascade",{"v":0.003785474,"d":"3.79E-03"},{"v":0.013657287,"d":"1.37E-02"},{"v":0.005305257,"d":"5.31E-03"},"PTPN6/SMAD4/AKT1",3,{"v":9.512567935,"d":"9.51"}]
["GO-BP","GO:0050864","regulation of B cell activation",{"v":0.003785474,"d":"3.79E-03"},{"v":0.013657287,"d":"1.37E-02"},{"v":0.005305257,"d":"5.31E-03"},"PTPN6/ATM/STAT6",3,{"v":9.512567935,"d":"9.51"}]
["GO-BP","GO:0050678","regulation of epithelial cell proliferation",{"v":0.003799198,"d":"3.80E-03"},{"v":0.013686994,"d":"1.37E-02"},{"v":0.005316796,"d":"5.32E-03"},"STAT3/STAT5A/AKT1/EGFR",4,{"v":6.173941799,"d":"6.17"}]
["GO-BP","GO:0007369","gastrulation",{"v":0.003843419,"d":"3.84E-03"},{"v":0.013779273,"d":"1.38E-02"},{"v":0.005352643,"d":"5.35E-03"},"TP53/SMAD4/SMAD2",3,{"v":9.461148649,"d":"9.46"}]
["GO-BP","GO:0032210","regulation of telomere maintenance via telomerase",{"v":0.003852448,"d":"3.85E-03"},{"v":0.013779273,"d":"1.38E-02"},{"v":0.005352643,"d":"5.35E-03"},"MAPK1/ATM",2,{"v":21.6087963,"d":"21.61"}]
["GO-BP","GO:0043392","negative regulation of DNA binding",{"v":0.003852448,"d":"3.85E-03"},{"v":0.013779273,"d":"1.38E-02"},{"v":0.005352643,"d":"5.35E-03"},"JAK2/NFKBIA",2,{"v":21.6087963,"d":"21.61"}]
["GO-BP","GO:0050994","regulation of lipid catabolic process",{"v":0.003852448,"d":"3.85E-03"},{"v":0.013779273,"d":"1.38E-02"},{"v":0.005352643,"d":"5.35E-03"},"PRKAA1/AKT1",2,{"v":21.6087963,"d":"21.61"}]
["GO-BP","GO:0097345","mitochondrial outer membrane permeabilization",{"v":0.003852448,"d":"3.85E-03"},{"v":0.013779273,"d":"1.38E-02"},{"v":0.005352643,"d":"5.35E-03"},"MAPK8/TP53",2,{"v":21.6087963,"d":"21.61"}]
["GO-BP","GO:0006869","lipid transport",{"v":0.003871295,"d":"3.87E-03"},{"v":0.013826847,"d":"1.38E-02"},{"v":0.005371123,"d":"5.37E-03"},"PTPN11/MAP2K6/NFKBIA/AKT1",4,{"v":6.141447368,"d":"6.14"}]
["GO-BP","GO:0048545","response to steroid hormone",{"v":0.003981183,"d":"3.98E-03"},{"v":0.014182264,"d":"1.42E-02"},{"v":0.005509187,"d":"5.51E-03"},"RBM14/JAK2/EIF4EBP1/EGFR",4,{"v":6.093342037,"d":"6.09"}]
["GO-BP","GO:0001541","ovarian follicle development",{"v":0.003993562,"d":"3.99E-03"},{"v":0.014182264,"d":"1.42E-02"},{"v":0.005509187,"d":"5.51E-03"},"SMAD4/ATM",2,{"v":21.21590909,"d":"21.22"}]
["GO-BP","GO:0016233","telomere capping",{"v":0.003993562,"d":"3.99E-03"},{"v":0.014182264,"d":"1.42E-02"},{"v":0.005509187,"d":"5.51E-03"},"MAPK1/ATM",2,{"v":21.21590909,"d":"21.22"}]
["GO-BP","GO:0042306","regulation of protein import into nucleus",{"v":0.003993562,"d":"3.99E-03"},{"v":0.014182264,"d":"1.42E-02"},{"v":0.005509187,"d":"5.51E-03"},"MAPK14/MAPK1",2,{"v":21.21590909,"d":"21.22"}]
["GO-BP","GO:0006977","DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",{"v":0.004137057,"d":"4.14E-03"},{"v":0.014629337,"d":"1.46E-02"},{"v":0.005682855,"d":"5.68E-03"},"TP53/ATM",2,{"v":20.83705357,"d":"20.84"}]
["GO-BP","GO:1903078","positive regulation of protein localization to plasma membrane",{"v":0.004137057,"d":"4.14E-03"},{"v":0.014629337,"d":"1.46E-02"},{"v":0.005682855,"d":"5.68E-03"},"AKT1/EGFR",2,{"v":20.83705357,"d":"20.84"}]
["GO-BP","GO:1903202","negative regulation of oxidative stress-induced cell death",{"v":0.004137057,"d":"4.14E-03"},{"v":0.014629337,"d":"1.46E-02"},{"v":0.005682855,"d":"5.68E-03"},"HSPB1/AKT1",2,{"v":20.83705357,"d":"20.84"}]
["GO-BP","GO:0001935","endothelial cell proliferation",{"v":0.004202515,"d":"4.20E-03"},{"v":0.014839759,"d":"1.48E-02"},{"v":0.005764595,"d":"5.76E-03"},"STAT3/STAT5A/AKT1",3,{"v":9.163939791,"d":"9.16"}]
["GO-BP","GO:0010665","regulation of cardiac muscle cell apoptotic process",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"TP53/JAK2",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0042743","hydrogen peroxide metabolic process",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"STAT3/EGFR",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0043525","positive regulation of neuron apoptotic process",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"TP53/ATM",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0048008","platelet-derived growth factor receptor signaling pathway",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"PTPN11/JAK2",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0060043","regulation of cardiac muscle cell proliferation",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"MAPK14/MAPK1",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0072431","signal transduction involved in mitotic G1 DNA damage checkpoint",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"TP53/ATM",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:1900408","negative regulation of cellular response to oxidative stress",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"HSPB1/AKT1",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:1902400","intracellular signal transduction involved in G1 DNA damage checkpoint",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"TP53/ATM",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:1903428","positive regulation of reactive oxygen species biosynthetic process",{"v":0.004282926,"d":"4.28E-03"},{"v":0.014933333,"d":"1.49E-02"},{"v":0.005800944,"d":"5.80E-03"},"JAK2/AKT1",2,{"v":20.47149123,"d":"20.47"}]
["GO-BP","GO:0006413","translational initiation",{"v":0.004326603,"d":"4.33E-03"},{"v":0.015064555,"d":"1.51E-02"},{"v":0.005851918,"d":"5.85E-03"},"HSPB1/EIF2S1/EIF4EBP1",3,{"v":9.068976684,"d":"9.07"}]
["GO-BP","GO:1902115","regulation of organelle assembly",{"v":0.004389477,"d":"4.39E-03"},{"v":0.015262155,"d":"1.53E-02"},{"v":0.005928677,"d":"5.93E-03"},"RBM14/SMAD4/PRKAA1",3,{"v":9.022229381,"d":"9.02"}]
["GO-BP","GO:0019229","regulation of vasoconstriction",{"v":0.00443116,"d":"4.43E-03"},{"v":0.01532161,"d":"1.53E-02"},{"v":0.005951773,"d":"5.95E-03"},"AKT1/EGFR",2,{"v":20.11853448,"d":"20.12"}]
["GO-BP","GO:0042093","T-helper cell differentiation",{"v":0.00443116,"d":"4.43E-03"},{"v":0.01532161,"d":"1.53E-02"},{"v":0.005951773,"d":"5.95E-03"},"STAT3/STAT6",2,{"v":20.11853448,"d":"20.12"}]
["GO-BP","GO:0071385","cellular response to glucocorticoid stimulus",{"v":0.00443116,"d":"4.43E-03"},{"v":0.01532161,"d":"1.53E-02"},{"v":0.005951773,"d":"5.95E-03"},"EIF4EBP1/EGFR",2,{"v":20.11853448,"d":"20.12"}]
["GO-BP","GO:1904589","regulation of protein import",{"v":0.00443116,"d":"4.43E-03"},{"v":0.01532161,"d":"1.53E-02"},{"v":0.005951773,"d":"5.95E-03"},"MAPK14/MAPK1",2,{"v":20.11853448,"d":"20.12"}]
["GO-BP","GO:0071897","DNA biosynthetic process",{"v":0.004516892,"d":"4.52E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"TP53/MAPK1/ATM",3,{"v":8.930165816,"d":"8.93"}]
["GO-BP","GO:0002221","pattern recognition receptor signaling pathway",{"v":0.004581435,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"MAP2K6/TBK1/NFKBIA",3,{"v":8.884835025,"d":"8.88"}]
["GO-BP","GO:0010952","positive regulation of peptidase activity",{"v":0.004581435,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"MAPK14/STAT3/JAK2",3,{"v":8.884835025,"d":"8.88"}]
["GO-BP","GO:0001836","release of cytochrome c from mitochondria",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"TP53/AKT1",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:0010662","regulation of striated muscle cell apoptotic process",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"TP53/JAK2",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:0031102","neuron projection regeneration",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"MAP2K1/JAK2",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:0032732","positive regulation of interleukin-1 production",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"HSPB1/JAK2",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:0032890","regulation of organic acid transport",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"MAP2K6/AKT1",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:0070527","platelet aggregation",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"PTPN6/HSPB1",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:0072413","signal transduction involved in mitotic cell cycle checkpoint",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"TP53/ATM",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:1902402","signal transduction involved in mitotic DNA damage checkpoint",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"TP53/ATM",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:1902403","signal transduction involved in mitotic DNA integrity checkpoint",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"TP53/ATM",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:1902883","negative regulation of response to oxidative stress",{"v":0.004581751,"d":"4.58E-03"},{"v":0.015561725,"d":"1.56E-02"},{"v":0.006045047,"d":"6.05E-03"},"HSPB1/AKT1",2,{"v":19.77754237,"d":"19.78"}]
["GO-BP","GO:0016052","carbohydrate catabolic process",{"v":0.004646539,"d":"4.65E-03"},{"v":0.015717533,"d":"1.57E-02"},{"v":0.006105571,"d":"6.11E-03"},"TP53/STAT3/PRKAA1",3,{"v":8.839962121,"d":"8.84"}]
["GO-BP","GO:0031099","regeneration",{"v":0.004646539,"d":"4.65E-03"},{"v":0.015717533,"d":"1.57E-02"},{"v":0.006105571,"d":"6.11E-03"},"MAP2K1/JAK2/EGFR",3,{"v":8.839962121,"d":"8.84"}]
["GO-BP","GO:0046890","regulation of lipid biosynthetic process",{"v":0.004646539,"d":"4.65E-03"},{"v":0.015717533,"d":"1.57E-02"},{"v":0.006105571,"d":"6.11E-03"},"CREB1/PRKAA1/AKT1",3,{"v":8.839962121,"d":"8.84"}]
["GO-BP","GO:0002294","CD4-positive, alpha-beta T cell differentiation involved in immune response",{"v":0.004734692,"d":"4.73E-03"},{"v":0.015929269,"d":"1.59E-02"},{"v":0.006187821,"d":"6.19E-03"},"STAT3/STAT6",2,{"v":19.44791667,"d":"19.45"}]
["GO-BP","GO:0010659","cardiac muscle cell apoptotic process",{"v":0.004734692,"d":"4.73E-03"},{"v":0.015929269,"d":"1.59E-02"},{"v":0.006187821,"d":"6.19E-03"},"TP53/JAK2",2,{"v":19.44791667,"d":"19.45"}]
["GO-BP","GO:1902110","positive regulation of mitochondrial membrane permeability involved in apoptotic process",{"v":0.004734692,"d":"4.73E-03"},{"v":0.015929269,"d":"1.59E-02"},{"v":0.006187821,"d":"6.19E-03"},"MAPK8/TP53",2,{"v":19.44791667,"d":"19.45"}]
["GO-BP","GO:1902808","positive regulation of cell cycle G1/S phase transition",{"v":0.004734692,"d":"4.73E-03"},{"v":0.015929269,"d":"1.59E-02"},{"v":0.006187821,"d":"6.19E-03"},"AKT1/EGFR",2,{"v":19.44791667,"d":"19.45"}]
["GO-BP","GO:0002287","alpha-beta T cell activation involved in immune response",{"v":0.004889975,"d":"4.89E-03"},{"v":0.016363366,"d":"1.64E-02"},{"v":0.006356449,"d":"6.36E-03"},"STAT3/STAT6",2,{"v":19.12909836,"d":"19.13"}]
["GO-BP","GO:0002293","alpha-beta T cell differentiation involved in immune response",{"v":0.004889975,"d":"4.89E-03"},{"v":0.016363366,"d":"1.64E-02"},{"v":0.006356449,"d":"6.36E-03"},"STAT3/STAT6",2,{"v":19.12909836,"d":"19.13"}]
["GO-BP","GO:0032370","positive regulation of lipid transport",{"v":0.004889975,"d":"4.89E-03"},{"v":0.016363366,"d":"1.64E-02"},{"v":0.006356449,"d":"6.36E-03"},"MAP2K6/NFKBIA",2,{"v":19.12909836,"d":"19.13"}]
["GO-BP","GO:0071384","cellular response to corticosteroid stimulus",{"v":0.004889975,"d":"4.89E-03"},{"v":0.016363366,"d":"1.64E-02"},{"v":0.006356449,"d":"6.36E-03"},"EIF4EBP1/EGFR",2,{"v":19.12909836,"d":"19.13"}]
["GO-BP","GO:0030278","regulation of ossification",{"v":0.004980501,"d":"4.98E-03"},{"v":0.016643954,"d":"1.66E-02"},{"v":0.006465445,"d":"6.47E-03"},"MAPK14/SMAD5/MAPK1",3,{"v":8.622229064,"d":"8.62"}]
["GO-BP","GO:0002562","somatic diversification of immune receptors via germline recombination within a single locus",{"v":0.005047591,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"ATM/STAT6",2,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:0002753","cytoplasmic pattern recognition receptor signaling pathway",{"v":0.005047591,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"MAP2K6/NFKBIA",2,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:0010658","striated muscle cell apoptotic process",{"v":0.005047591,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"TP53/JAK2",2,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:0016444","somatic cell DNA recombination",{"v":0.005047591,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"ATM/STAT6",2,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:1902686","mitochondrial outer membrane permeabilization involved in programmed cell death",{"v":0.005047591,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"MAPK8/TP53",2,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:1904356","regulation of telomere maintenance via telomere lengthening",{"v":0.005047591,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"MAPK1/ATM",2,{"v":18.82056452,"d":"18.82"}]
["GO-BP","GO:0006473","protein acetylation",{"v":0.005048993,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"SMAD4/RPS6KA4/PRKAA1",3,{"v":8.579963235,"d":"8.58"}]
["GO-BP","GO:0034764","positive regulation of transmembrane transport",{"v":0.005048993,"d":"5.05E-03"},{"v":0.016693817,"d":"1.67E-02"},{"v":0.006484815,"d":"6.48E-03"},"MAPK14/PTPN11/AKT1",3,{"v":8.579963235,"d":"8.58"}]
["GO-BP","GO:0031571","mitotic G1 DNA damage checkpoint",{"v":0.005207533,"d":"5.21E-03"},{"v":0.017127149,"d":"1.71E-02"},{"v":0.006653146,"d":"6.65E-03"},"TP53/ATM",2,{"v":18.5218254,"d":"18.52"}]
["GO-BP","GO:0044819","mitotic G1/S transition checkpoint",{"v":0.005207533,"d":"5.21E-03"},{"v":0.017127149,"d":"1.71E-02"},{"v":0.006653146,"d":"6.65E-03"},"TP53/ATM",2,{"v":18.5218254,"d":"18.52"}]
["GO-BP","GO:0046888","negative regulation of hormone secretion",{"v":0.005207533,"d":"5.21E-03"},{"v":0.017127149,"d":"1.71E-02"},{"v":0.006653146,"d":"6.65E-03"},"PTPN11/PSMD9",2,{"v":18.5218254,"d":"18.52"}]
["GO-BP","GO:1904377","positive regulation of protein localization to cell periphery",{"v":0.005207533,"d":"5.21E-03"},{"v":0.017127149,"d":"1.71E-02"},{"v":0.006653146,"d":"6.65E-03"},"AKT1/EGFR",2,{"v":18.5218254,"d":"18.52"}]
["GO-BP","GO:0070555","response to interleukin-1",{"v":0.005257889,"d":"5.26E-03"},{"v":0.017269982,"d":"1.73E-02"},{"v":0.00670863,"d":"6.71E-03"},"RPS6KA4/NFKBIA/PSMD9",3,{"v":8.455615942,"d":"8.46"}]
["GO-BP","GO:0010876","lipid localization",{"v":0.005288266,"d":"5.29E-03"},{"v":0.017346904,"d":"1.73E-02"},{"v":0.006738511,"d":"6.74E-03"},"PTPN11/MAP2K6/NFKBIA/AKT1",4,{"v":5.623493976,"d":"5.62"}]
["GO-BP","GO:0050670","regulation of lymphocyte proliferation",{"v":0.005328666,"d":"5.33E-03"},{"v":0.017456458,"d":"1.75E-02"},{"v":0.006781068,"d":"6.78E-03"},"PTPN6/ATM/ZAP70",3,{"v":8.414963942,"d":"8.41"}]
["GO-BP","GO:0035794","positive regulation of mitochondrial membrane permeability",{"v":0.005369792,"d":"5.37E-03"},{"v":0.01747636,"d":"1.75E-02"},{"v":0.006788799,"d":"6.79E-03"},"MAPK8/TP53",2,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:0044783","G1 DNA damage checkpoint",{"v":0.005369792,"d":"5.37E-03"},{"v":0.01747636,"d":"1.75E-02"},{"v":0.006788799,"d":"6.79E-03"},"TP53/ATM",2,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:0048645","animal organ formation",{"v":0.005369792,"d":"5.37E-03"},{"v":0.01747636,"d":"1.75E-02"},{"v":0.006788799,"d":"6.79E-03"},"MAP2K1/MAPK1",2,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:0060135","maternal process involved in female pregnancy",{"v":0.005369792,"d":"5.37E-03"},{"v":0.01747636,"d":"1.75E-02"},{"v":0.006788799,"d":"6.79E-03"},"MAPK1/AKT1",2,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:2000378","negative regulation of reactive oxygen species metabolic process",{"v":0.005369792,"d":"5.37E-03"},{"v":0.01747636,"d":"1.75E-02"},{"v":0.006788799,"d":"6.79E-03"},"TP53/STAT3",2,{"v":18.23242188,"d":"18.23"}]
["GO-BP","GO:0017148","negative regulation of translation",{"v":0.005400018,"d":"5.40E-03"},{"v":0.017528966,"d":"1.75E-02"},{"v":0.006809234,"d":"6.81E-03"},"EIF2S1/STAT3/EIF4EBP1",3,{"v":8.374700957,"d":"8.37"}]
["GO-BP","GO:0032944","regulation of mononuclear cell proliferation",{"v":0.005400018,"d":"5.40E-03"},{"v":0.017528966,"d":"1.75E-02"},{"v":0.006809234,"d":"6.81E-03"},"PTPN6/ATM/ZAP70",3,{"v":8.374700957,"d":"8.37"}]
["GO-BP","GO:0043523","regulation of neuron apoptotic process",{"v":0.005471947,"d":"5.47E-03"},{"v":0.017739355,"d":"1.77E-02"},{"v":0.006890961,"d":"6.89E-03"},"TP53/ATM/JAK2",3,{"v":8.334821429,"d":"8.33"}]
["GO-BP","GO:0014823","response to activity",{"v":0.005534361,"d":"5.53E-03"},{"v":0.017895153,"d":"1.79E-02"},{"v":0.006951481,"d":"6.95E-03"},"CREB1/PRKAA1",2,{"v":17.95192308,"d":"17.95"}]
["GO-BP","GO:0032768","regulation of monooxygenase activity",{"v":0.005534361,"d":"5.53E-03"},{"v":0.017895153,"d":"1.79E-02"},{"v":0.006951481,"d":"6.95E-03"},"AKT1/EGFR",2,{"v":17.95192308,"d":"17.95"}]
["GO-BP","GO:1902749","regulation of cell cycle G2/M phase transition",{"v":0.005691203,"d":"5.69E-03"},{"v":0.018292371,"d":"1.83E-02"},{"v":0.007105783,"d":"7.11E-03"},"TP53/ATM/PSMD9",3,{"v":8.217429577,"d":"8.22"}]
["GO-BP","GO:0045428","regulation of nitric oxide biosynthetic process",{"v":0.005701232,"d":"5.70E-03"},{"v":0.018292371,"d":"1.83E-02"},{"v":0.007105783,"d":"7.11E-03"},"JAK2/AKT1",2,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:0046626","regulation of insulin receptor signaling pathway",{"v":0.005701232,"d":"5.70E-03"},{"v":0.018292371,"d":"1.83E-02"},{"v":0.007105783,"d":"7.11E-03"},"PTPN11/PRKAA1",2,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:1902108","regulation of mitochondrial membrane permeability involved in apoptotic process",{"v":0.005701232,"d":"5.70E-03"},{"v":0.018292371,"d":"1.83E-02"},{"v":0.007105783,"d":"7.11E-03"},"MAPK8/TP53",2,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:1905207","regulation of cardiocyte differentiation",{"v":0.005701232,"d":"5.70E-03"},{"v":0.018292371,"d":"1.83E-02"},{"v":0.007105783,"d":"7.11E-03"},"SMAD4/EGFR",2,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:1905710","positive regulation of membrane permeability",{"v":0.005701232,"d":"5.70E-03"},{"v":0.018292371,"d":"1.83E-02"},{"v":0.007105783,"d":"7.11E-03"},"MAPK8/TP53",2,{"v":17.67992424,"d":"17.68"}]
["GO-BP","GO:0009896","positive regulation of catabolic process",{"v":0.005749523,"d":"5.75E-03"},{"v":0.018380135,"d":"1.84E-02"},{"v":0.007139876,"d":"7.14E-03"},"ATM/TBK1/PRKAA1/AKT1",4,{"v":5.491176471,"d":"5.49"}]
["GO-BP","GO:0052548","regulation of endopeptidase activity",{"v":0.005749523,"d":"5.75E-03"},{"v":0.018380135,"d":"1.84E-02"},{"v":0.007139876,"d":"7.14E-03"},"RPS6KA1/STAT3/JAK2/AKT1",4,{"v":5.491176471,"d":"5.49"}]
["GO-BP","GO:0007254","JNK cascade",{"v":0.005765449,"d":"5.77E-03"},{"v":0.018380135,"d":"1.84E-02"},{"v":0.007139876,"d":"7.14E-03"},"MAPK8/AKT1/EGFR",3,{"v":8.179030374,"d":"8.18"}]
["GO-BP","GO:0045089","positive regulation of innate immune response",{"v":0.005765449,"d":"5.77E-03"},{"v":0.018380135,"d":"1.84E-02"},{"v":0.007139876,"d":"7.14E-03"},"RBM14/TBK1/PSMD9",3,{"v":8.179030374,"d":"8.18"}]
["GO-BP","GO:2001020","regulation of response to DNA damage stimulus",{"v":0.005765449,"d":"5.77E-03"},{"v":0.018380135,"d":"1.84E-02"},{"v":0.007139876,"d":"7.14E-03"},"TP53/ATM/EGFR",3,{"v":8.179030374,"d":"8.18"}]
["GO-BP","GO:0043281","regulation of cysteine-type endopeptidase activity involved in apoptotic process",{"v":0.005840279,"d":"5.84E-03"},{"v":0.018571192,"d":"1.86E-02"},{"v":0.007214093,"d":"7.21E-03"},"RPS6KA1/JAK2/AKT1",3,{"v":8.140988372,"d":"8.14"}]
["GO-BP","GO:0070374","positive regulation of ERK1 and ERK2 cascade",{"v":0.005840279,"d":"5.84E-03"},{"v":0.018571192,"d":"1.86E-02"},{"v":0.007214093,"d":"7.21E-03"},"MAP2K1/PTPN11/EGFR",3,{"v":8.140988372,"d":"8.14"}]
["GO-BP","GO:0060038","cardiac muscle cell proliferation",{"v":0.005870397,"d":"5.87E-03"},{"v":0.018619466,"d":"1.86E-02"},{"v":0.007232845,"d":"7.23E-03"},"MAPK14/MAPK1",2,{"v":17.41604478,"d":"17.42"}]
["GO-BP","GO:2000573","positive regulation of DNA biosynthetic process",{"v":0.005870397,"d":"5.87E-03"},{"v":0.018619466,"d":"1.86E-02"},{"v":0.007232845,"d":"7.23E-03"},"MAPK1/ATM",2,{"v":17.41604478,"d":"17.42"}]
["GO-BP","GO:0001933","negative regulation of protein phosphorylation",{"v":0.005941356,"d":"5.94E-03"},{"v":0.018820586,"d":"1.88E-02"},{"v":0.007310971,"d":"7.31E-03"},"PTPN6/HSPB1/SMAD4/AKT1",4,{"v":5.43997669,"d":"5.44"}]
["GO-BP","GO:0043393","regulation of protein binding",{"v":0.00599169,"d":"5.99E-03"},{"v":0.018955943,"d":"1.90E-02"},{"v":0.007363552,"d":"7.36E-03"},"MAPK8/EIF2S1/AKT1",3,{"v":8.065956221,"d":"8.07"}]
["GO-BP","GO:0002292","T cell differentiation involved in immune response",{"v":0.006041849,"d":"6.04E-03"},{"v":0.019066239,"d":"1.91E-02"},{"v":0.007406397,"d":"7.41E-03"},"STAT3/STAT6",2,{"v":17.15992647,"d":"17.16"}]
["GO-BP","GO:0033627","cell adhesion mediated by integrin",{"v":0.006041849,"d":"6.04E-03"},{"v":0.019066239,"d":"1.91E-02"},{"v":0.007406397,"d":"7.41E-03"},"PTPN6/PTPN11",2,{"v":17.15992647,"d":"17.16"}]
["GO-BP","GO:0019722","calcium-mediated signaling",{"v":0.006068275,"d":"6.07E-03"},{"v":0.019125422,"d":"1.91E-02"},{"v":0.007429387,"d":"7.43E-03"},"ZAP70/PRKAA1/EGFR",3,{"v":8.028956422,"d":"8.03"}]
["GO-BP","GO:0042698","ovulation cycle",{"v":0.006215578,"d":"6.22E-03"},{"v":0.019515041,"d":"1.95E-02"},{"v":0.007580737,"d":"7.58E-03"},"MAP2K6/EGFR",2,{"v":16.91123188,"d":"16.91"}]
["GO-BP","GO:0070227","lymphocyte apoptotic process",{"v":0.006215578,"d":"6.22E-03"},{"v":0.019515041,"d":"1.95E-02"},{"v":0.007580737,"d":"7.58E-03"},"TP53/AKT1",2,{"v":16.91123188,"d":"16.91"}]
["GO-BP","GO:0071300","cellular response to retinoic acid",{"v":0.006215578,"d":"6.22E-03"},{"v":0.019515041,"d":"1.95E-02"},{"v":0.007580737,"d":"7.58E-03"},"ATM/CREB1",2,{"v":16.91123188,"d":"16.91"}]
["GO-BP","GO:0048762","mesenchymal cell differentiation",{"v":0.006223208,"d":"6.22E-03"},{"v":0.019515041,"d":"1.95E-02"},{"v":0.007580737,"d":"7.58E-03"},"SMAD4/MAPK1/SMAD2",3,{"v":7.955965909,"d":"7.96"}]
["GO-BP","GO:0070663","regulation of leukocyte proliferation",{"v":0.006380502,"d":"6.38E-03"},{"v":0.019942684,"d":"1.99E-02"},{"v":0.007746857,"d":"7.75E-03"},"PTPN6/ATM/ZAP70",3,{"v":7.884290541,"d":"7.88"}]
["GO-BP","GO:0007004","telomere maintenance via telomerase",{"v":0.006391578,"d":"6.39E-03"},{"v":0.019942684,"d":"1.99E-02"},{"v":0.007746857,"d":"7.75E-03"},"MAPK1/ATM",2,{"v":16.66964286,"d":"16.67"}]
["GO-BP","GO:0033077","T cell differentiation in thymus",{"v":0.006391578,"d":"6.39E-03"},{"v":0.019942684,"d":"1.99E-02"},{"v":0.007746857,"d":"7.75E-03"},"TP53/ZAP70",2,{"v":16.66964286,"d":"16.67"}]
["GO-BP","GO:0061515","myeloid cell development",{"v":0.006391578,"d":"6.39E-03"},{"v":0.019942684,"d":"1.99E-02"},{"v":0.007746857,"d":"7.75E-03"},"PTPN6/PTPN11",2,{"v":16.66964286,"d":"16.67"}]
["GO-BP","GO:0045444","fat cell differentiation",{"v":0.006460037,"d":"6.46E-03"},{"v":0.020131089,"d":"2.01E-02"},{"v":0.007820044,"d":"7.82E-03"},"MAPK14/CREB1/AKT1",3,{"v":7.848934978,"d":"7.85"}]
["GO-BP","GO:0042531","positive regulation of tyrosine phosphorylation of STAT protein",{"v":0.006569841,"d":"6.57E-03"},{"v":0.020447708,"d":"2.04E-02"},{"v":0.007943037,"d":"7.94E-03"},"STAT3/JAK2",2,{"v":16.43485915,"d":"16.43"}]
["GO-BP","GO:0032024","positive regulation of insulin secretion",{"v":0.006750359,"d":"6.75E-03"},{"v":0.020961167,"d":"2.10E-02"},{"v":0.008142493,"d":"8.14E-03"},"JAK2/PSMD9",2,{"v":16.20659722,"d":"16.21"}]
["GO-BP","GO:0010256","endomembrane system organization",{"v":0.006751631,"d":"6.75E-03"},{"v":0.020961167,"d":"2.10E-02"},{"v":0.008142493,"d":"8.14E-03"},"MAP2K1/MAPK1/CREB1/AKT1",4,{"v":5.244382022,"d":"5.24"}]
["GO-BP","GO:0032945","negative regulation of mononuclear cell proliferation",{"v":0.006933124,"d":"6.93E-03"},{"v":0.021391433,"d":"2.14E-02"},{"v":0.008309633,"d":"8.31E-03"},"PTPN6/ATM",2,{"v":15.98458904,"d":"15.98"}]
["GO-BP","GO:0050672","negative regulation of lymphocyte proliferation",{"v":0.006933124,"d":"6.93E-03"},{"v":0.021391433,"d":"2.14E-02"},{"v":0.008309633,"d":"8.31E-03"},"PTPN6/ATM",2,{"v":15.98458904,"d":"15.98"}]
["GO-BP","GO:0072401","signal transduction involved in DNA integrity checkpoint",{"v":0.006933124,"d":"6.93E-03"},{"v":0.021391433,"d":"2.14E-02"},{"v":0.008309633,"d":"8.31E-03"},"TP53/ATM",2,{"v":15.98458904,"d":"15.98"}]
["GO-BP","GO:0072422","signal transduction involved in DNA damage checkpoint",{"v":0.006933124,"d":"6.93E-03"},{"v":0.021391433,"d":"2.14E-02"},{"v":0.008309633,"d":"8.31E-03"},"TP53/ATM",2,{"v":15.98458904,"d":"15.98"}]
["GO-BP","GO:1903524","positive regulation of blood circulation",{"v":0.006933124,"d":"6.93E-03"},{"v":0.021391433,"d":"2.14E-02"},{"v":0.008309633,"d":"8.31E-03"},"AKT1/EGFR",2,{"v":15.98458904,"d":"15.98"}]
["GO-BP","GO:0001894","tissue homeostasis",{"v":0.006949752,"d":"6.95E-03"},{"v":0.021416232,"d":"2.14E-02"},{"v":0.008319266,"d":"8.32E-03"},"HSPB1/PTPN11/EGFR",3,{"v":7.643286026,"d":"7.64"}]
["GO-BP","GO:0009743","response to carbohydrate",{"v":0.007033466,"d":"7.03E-03"},{"v":0.021647445,"d":"2.16E-02"},{"v":0.008409082,"d":"8.41E-03"},"MAP2K6/PRKAA1/SMAD2",3,{"v":7.610054348,"d":"7.61"}]
["GO-BP","GO:0043367","CD4-positive, alpha-beta T cell differentiation",{"v":0.007118128,"d":"7.12E-03"},{"v":0.021827176,"d":"2.18E-02"},{"v":0.0084789,"d":"8.48E-03"},"STAT3/STAT6",2,{"v":15.76858108,"d":"15.77"}]
["GO-BP","GO:0072395","signal transduction involved in cell cycle checkpoint",{"v":0.007118128,"d":"7.12E-03"},{"v":0.021827176,"d":"2.18E-02"},{"v":0.0084789,"d":"8.48E-03"},"TP53/ATM",2,{"v":15.76858108,"d":"15.77"}]
["GO-BP","GO:1900076","regulation of cellular response to insulin stimulus",{"v":0.007118128,"d":"7.12E-03"},{"v":0.021827176,"d":"2.18E-02"},{"v":0.0084789,"d":"8.48E-03"},"PTPN11/PRKAA1",2,{"v":15.76858108,"d":"15.77"}]
["GO-BP","GO:0009755","hormone-mediated signaling pathway",{"v":0.007288222,"d":"7.29E-03"},{"v":0.022318963,"d":"2.23E-02"},{"v":0.008669937,"d":"8.67E-03"},"RBM14/PTPN11/JAK2",3,{"v":7.512070815,"d":"7.51"}]
["GO-BP","GO:0002200","somatic diversification of immune receptors",{"v":0.007305365,"d":"7.31E-03"},{"v":0.022318963,"d":"2.23E-02"},{"v":0.008669937,"d":"8.67E-03"},"ATM/STAT6",2,{"v":15.55833333,"d":"15.56"}]
["GO-BP","GO:1903201","regulation of oxidative stress-induced cell death",{"v":0.007305365,"d":"7.31E-03"},{"v":0.022318963,"d":"2.23E-02"},{"v":0.008669937,"d":"8.67E-03"},"HSPB1/AKT1",2,{"v":15.55833333,"d":"15.56"}]
["GO-BP","GO:0006469","negative regulation of protein kinase activity",{"v":0.007461081,"d":"7.46E-03"},{"v":0.0227668,"d":"2.28E-02"},{"v":0.008843902,"d":"8.84E-03"},"PTPN6/HSPB1/AKT1",3,{"v":7.448138298,"d":"7.45"}]
["GO-BP","GO:0007492","endoderm development",{"v":0.007494825,"d":"7.49E-03"},{"v":0.022786096,"d":"2.28E-02"},{"v":0.008851398,"d":"8.85E-03"},"SMAD4/SMAD2",2,{"v":15.35361842,"d":"15.35"}]
["GO-BP","GO:0042310","vasoconstriction",{"v":0.007494825,"d":"7.49E-03"},{"v":0.022786096,"d":"2.28E-02"},{"v":0.008851398,"d":"8.85E-03"},"AKT1/EGFR",2,{"v":15.35361842,"d":"15.35"}]
["GO-BP","GO:0060411","cardiac septum morphogenesis",{"v":0.007494825,"d":"7.49E-03"},{"v":0.022786096,"d":"2.28E-02"},{"v":0.008851398,"d":"8.85E-03"},"TP53/SMAD4",2,{"v":15.35361842,"d":"15.35"}]
["GO-BP","GO:0043122","regulation of I-kappaB kinase/NF-kappaB signaling",{"v":0.007636368,"d":"7.64E-03"},{"v":0.023188144,"d":"2.32E-02"},{"v":0.009007576,"d":"9.01E-03"},"HSPB1/TBK1/AKT1",3,{"v":7.38528481,"d":"7.39"}]
["GO-BP","GO:0006110","regulation of glycolytic process",{"v":0.007686502,"d":"7.69E-03"},{"v":0.023199091,"d":"2.32E-02"},{"v":0.009011828,"d":"9.01E-03"},"STAT3/PRKAA1",2,{"v":15.15422078,"d":"15.15"}]
["GO-BP","GO:0006278","RNA-dependent DNA biosynthetic process",{"v":0.007686502,"d":"7.69E-03"},{"v":0.023199091,"d":"2.32E-02"},{"v":0.009011828,"d":"9.01E-03"},"MAPK1/ATM",2,{"v":15.15422078,"d":"15.15"}]
["GO-BP","GO:0006809","nitric oxide biosynthetic process",{"v":0.007686502,"d":"7.69E-03"},{"v":0.023199091,"d":"2.32E-02"},{"v":0.009011828,"d":"9.01E-03"},"JAK2/AKT1",2,{"v":15.15422078,"d":"15.15"}]
["GO-BP","GO:0048678","response to axon injury",{"v":0.007686502,"d":"7.69E-03"},{"v":0.023199091,"d":"2.32E-02"},{"v":0.009011828,"d":"9.01E-03"},"MAP2K1/JAK2",2,{"v":15.15422078,"d":"15.15"}]
["GO-BP","GO:0061418","regulation of transcription from RNA polymerase II promoter in response to hypoxia",{"v":0.007686502,"d":"7.69E-03"},{"v":0.023199091,"d":"2.32E-02"},{"v":0.009011828,"d":"9.01E-03"},"TP53/PSMD9",2,{"v":15.15422078,"d":"15.15"}]
["GO-BP","GO:0030258","lipid modification",{"v":0.007724925,"d":"7.72E-03"},{"v":0.023286865,"d":"2.33E-02"},{"v":0.009045925,"d":"9.05E-03"},"MAPK14/PRKAA1/AKT1",3,{"v":7.354254202,"d":"7.35"}]
["GO-BP","GO:0051402","neuron apoptotic process",{"v":0.007814091,"d":"7.81E-03"},{"v":0.023498828,"d":"2.35E-02"},{"v":0.009128263,"d":"9.13E-03"},"TP53/ATM/JAK2",3,{"v":7.323483264,"d":"7.32"}]
["GO-BP","GO:2000116","regulation of cysteine-type endopeptidase activity",{"v":0.007814091,"d":"7.81E-03"},{"v":0.023498828,"d":"2.35E-02"},{"v":0.009128263,"d":"9.13E-03"},"RPS6KA1/JAK2/AKT1",3,{"v":7.323483264,"d":"7.32"}]
["GO-BP","GO:0031016","pancreas development",{"v":0.007880387,"d":"7.88E-03"},{"v":0.023612747,"d":"2.36E-02"},{"v":0.009172515,"d":"9.17E-03"},"SMAD2/AKT1",2,{"v":14.9599359,"d":"14.96"}]
["GO-BP","GO:0055021","regulation of cardiac muscle tissue growth",{"v":0.007880387,"d":"7.88E-03"},{"v":0.023612747,"d":"2.36E-02"},{"v":0.009172515,"d":"9.17E-03"},"MAPK14/MAPK1",2,{"v":14.9599359,"d":"14.96"}]
["GO-BP","GO:0070664","negative regulation of leukocyte proliferation",{"v":0.007880387,"d":"7.88E-03"},{"v":0.023612747,"d":"2.36E-02"},{"v":0.009172515,"d":"9.17E-03"},"PTPN6/ATM",2,{"v":14.9599359,"d":"14.96"}]
["GO-BP","GO:0038093","Fc receptor signaling pathway",{"v":0.007994257,"d":"7.99E-03"},{"v":0.023896503,"d":"2.39E-02"},{"v":0.009282742,"d":"9.28E-03"},"MAPK8/MAPK1/PSMD9",3,{"v":7.262707469,"d":"7.26"}]
["GO-BP","GO:0090092","regulation of transmembrane receptor protein serine/threonine kinase signaling pathway",{"v":0.007994257,"d":"7.99E-03"},{"v":0.023896503,"d":"2.39E-02"},{"v":0.009282742,"d":"9.28E-03"},"TP53/SMAD4/SMAD2",3,{"v":7.262707469,"d":"7.26"}]
["GO-BP","GO:0045913","positive regulation of carbohydrate metabolic process",{"v":0.008076474,"d":"8.08E-03"},{"v":0.024084508,"d":"2.41E-02"},{"v":0.009355774,"d":"9.36E-03"},"PRKAA1/AKT1",2,{"v":14.77056962,"d":"14.77"}]
["GO-BP","GO:1900034","regulation of cellular response to heat",{"v":0.008076474,"d":"8.08E-03"},{"v":0.024084508,"d":"2.41E-02"},{"v":0.009355774,"d":"9.36E-03"},"MAPK1/ATM",2,{"v":14.77056962,"d":"14.77"}]
["GO-BP","GO:0031334","positive regulation of protein-containing complex assembly",{"v":0.008269107,"d":"8.27E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53/ATM/CREB1",3,{"v":7.173411885,"d":"7.17"}]
["GO-BP","GO:0051896","regulation of protein kinase B signaling",{"v":0.008269107,"d":"8.27E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PTPN11/AKT1/EGFR",3,{"v":7.173411885,"d":"7.17"}]
["GO-BP","GO:0003012","muscle system process",{"v":0.008280554,"d":"8.28E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"MAP2K3/SMAD4/SMAD5/MAP2K6",4,{"v":4.944385593,"d":"4.94"}]
["GO-BP","GO:0002429","immune response-activating cell surface receptor signaling pathway",{"v":0.008341205,"d":"8.34E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PTPN6/MAPK1/ZAP70/PSMD9",4,{"v":4.933932347,"d":"4.93"}]
["GO-BP","GO:0002757","immune response-activating signal transduction",{"v":0.008341205,"d":"8.34E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PTPN6/MAPK1/ZAP70/PSMD9",4,{"v":4.933932347,"d":"4.93"}]
["GO-BP","GO:0030512","negative regulation of transforming growth factor beta receptor signaling pathway",{"v":0.008475219,"d":"8.48E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53/SMAD2",2,{"v":14.4058642,"d":"14.41"}]
["GO-BP","GO:0032204","regulation of telomere maintenance",{"v":0.008475219,"d":"8.48E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"MAPK1/ATM",2,{"v":14.4058642,"d":"14.41"}]
["GO-BP","GO:0034109","homotypic cell-cell adhesion",{"v":0.008475219,"d":"8.48E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PTPN6/HSPB1",2,{"v":14.4058642,"d":"14.41"}]
["GO-BP","GO:0002190","cap-independent translational initiation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"EIF4EBP1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0002309","T cell proliferation involved in immune response",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0002329","pre-B cell differentiation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"ATM",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0010750","positive regulation of nitric oxide mediated signal transduction",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"EGFR",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0015911","long-chain fatty acid import across plasma membrane",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"AKT1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0019659","glucose catabolic process to lactate",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0019660","glycolytic fermentation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0019661","glucose catabolic process to lactate via pyruvate",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0031999","negative regulation of fatty acid beta-oxidation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"AKT1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0032077","positive regulation of deoxyribonuclease activity",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"AKT1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0032907","transforming growth factor beta3 production",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"CREB1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0032910","regulation of transforming growth factor beta3 production",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"CREB1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0038033","positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"HSPB1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0043504","mitochondrial DNA repair",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0043987","histone H3-S10 phosphorylation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"RPS6KA4",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0048859","formation of anatomical boundary",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"SMAD4",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0051097","negative regulation of helicase activity",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0060398","regulation of growth hormone receptor signaling pathway",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"JAK2",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0060509","type I pneumocyte differentiation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"CREB1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0062028","regulation of stress granule assembly",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PRKAA1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0070245","positive regulation of thymocyte apoptotic process",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0072656","maintenance of protein location in mitochondrion",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"AKT1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0072708","response to sorbitol",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"MAP2K6",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0080184","response to phenylpropanoid",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"EGFR",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0090155","negative regulation of sphingolipid biosynthetic process",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PRKAA1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1900019","regulation of protein kinase C activity",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"EGFR",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1900020","positive regulation of protein kinase C activity",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"EGFR",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1900060","negative regulation of ceramide biosynthetic process",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PRKAA1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1900145","regulation of nodal signaling pathway involved in determination of left/right asymmetry",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"SMAD2",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1900175","regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"SMAD2",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1901563","response to camptothecin",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PRKAA1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1902688","regulation of NAD metabolic process",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1903721","positive regulation of I-kappaB phosphorylation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"AKT1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1904023","regulation of glucose catabolic process to lactate via pyruvate",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"TP53",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1904428","negative regulation of tubulin deacetylation",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"PRKAA1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:1905098","negative regulation of guanyl-nucleotide exchange factor activity",{"v":0.008541483,"d":"8.54E-03"},{"v":0.024197634,"d":"2.42E-02"},{"v":0.009399718,"d":"9.40E-03"},"EIF2S1",1,{"v":116.6875,"d":"116.69"}]
["GO-BP","GO:0043543","protein acylation",{"v":0.0086442,"d":"8.64E-03"},{"v":0.024389982,"d":"2.44E-02"},{"v":0.009474437,"d":"9.47E-03"},"SMAD4/RPS6KA4/PRKAA1",3,{"v":7.057711694,"d":"7.06"}]
["GO-BP","GO:1901991","negative regulation of mitotic cell cycle phase transition",{"v":0.0086442,"d":"8.64E-03"},{"v":0.024389982,"d":"2.44E-02"},{"v":0.009474437,"d":"9.47E-03"},"TP53/ATM/PSMD9",3,{"v":7.057711694,"d":"7.06"}]
["GO-BP","GO:0010833","telomere maintenance via telomere lengthening",{"v":0.008677863,"d":"8.68E-03"},{"v":0.024389982,"d":"2.44E-02"},{"v":0.009474437,"d":"9.47E-03"},"MAPK1/ATM",2,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:0034644","cellular response to UV",{"v":0.008677863,"d":"8.68E-03"},{"v":0.024389982,"d":"2.44E-02"},{"v":0.009474437,"d":"9.47E-03"},"TP53/EIF2S1",2,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:0046209","nitric oxide metabolic process",{"v":0.008677863,"d":"8.68E-03"},{"v":0.024389982,"d":"2.44E-02"},{"v":0.009474437,"d":"9.47E-03"},"JAK2/AKT1",2,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:0071158","positive regulation of cell cycle arrest",{"v":0.008677863,"d":"8.68E-03"},{"v":0.024389982,"d":"2.44E-02"},{"v":0.009474437,"d":"9.47E-03"},"TP53/ATM",2,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:1905954","positive regulation of lipid localization",{"v":0.008677863,"d":"8.68E-03"},{"v":0.024389982,"d":"2.44E-02"},{"v":0.009474437,"d":"9.47E-03"},"MAP2K6/NFKBIA",2,{"v":14.23018293,"d":"14.23"}]
["GO-BP","GO:0002833","positive regulation of response to biotic stimulus",{"v":0.00873952,"d":"8.74E-03"},{"v":0.024535611,"d":"2.45E-02"},{"v":0.009531008,"d":"9.53E-03"},"RBM14/TBK1/PSMD9",3,{"v":7.02936747,"d":"7.03"}]
["GO-BP","GO:0006970","response to osmotic stress",{"v":0.008882678,"d":"8.88E-03"},{"v":0.024825691,"d":"2.48E-02"},{"v":0.009643691,"d":"9.64E-03"},"TP53/EGFR",2,{"v":14.05873494,"d":"14.06"}]
["GO-BP","GO:0042509","regulation of tyrosine phosphorylation of STAT protein",{"v":0.008882678,"d":"8.88E-03"},{"v":0.024825691,"d":"2.48E-02"},{"v":0.009643691,"d":"9.64E-03"},"STAT3/JAK2",2,{"v":14.05873494,"d":"14.06"}]
["GO-BP","GO:0060218","hematopoietic stem cell differentiation",{"v":0.008882678,"d":"8.88E-03"},{"v":0.024825691,"d":"2.48E-02"},{"v":0.009643691,"d":"9.64E-03"},"TP53/PSMD9",2,{"v":14.05873494,"d":"14.06"}]
["GO-BP","GO:1903845","negative regulation of cellular response to transforming growth factor beta stimulus",{"v":0.008882678,"d":"8.88E-03"},{"v":0.024825691,"d":"2.48E-02"},{"v":0.009643691,"d":"9.64E-03"},"TP53/SMAD2",2,{"v":14.05873494,"d":"14.06"}]
["GO-BP","GO:0043154","negative regulation of cysteine-type endopeptidase activity involved in apoptotic process",{"v":0.009089656,"d":"9.09E-03"},{"v":0.025290751,"d":"2.53E-02"},{"v":0.009824346,"d":"9.82E-03"},"RPS6KA1/AKT1",2,{"v":13.89136905,"d":"13.89"}]
["GO-BP","GO:0050886","endocrine process",{"v":0.009089656,"d":"9.09E-03"},{"v":0.025290751,"d":"2.53E-02"},{"v":0.009824346,"d":"9.82E-03"},"SMAD4/PTPN11",2,{"v":13.89136905,"d":"13.89"}]
["GO-BP","GO:0060420","regulation of heart growth",{"v":0.009089656,"d":"9.09E-03"},{"v":0.025290751,"d":"2.53E-02"},{"v":0.009824346,"d":"9.82E-03"},"MAPK14/MAPK1",2,{"v":13.89136905,"d":"13.89"}]
["GO-BP","GO:0097756","negative regulation of blood vessel diameter",{"v":0.009089656,"d":"9.09E-03"},{"v":0.025290751,"d":"2.53E-02"},{"v":0.009824346,"d":"9.82E-03"},"AKT1/EGFR",2,{"v":13.89136905,"d":"13.89"}]
["GO-BP","GO:0009798","axis specification",{"v":0.00929879,"d":"9.30E-03"},{"v":0.025815014,"d":"2.58E-02"},{"v":0.010028,"d":"1.00E-02"},"SMAD4/SMAD2",2,{"v":13.72794118,"d":"13.73"}]
["GO-BP","GO:2001057","reactive nitrogen species metabolic process",{"v":0.00929879,"d":"9.30E-03"},{"v":0.025815014,"d":"2.58E-02"},{"v":0.010028,"d":"1.00E-02"},"JAK2/AKT1",2,{"v":13.72794118,"d":"13.73"}]
["GO-BP","GO:0007611","learning or memory",{"v":0.009424184,"d":"9.42E-03"},{"v":0.026134028,"d":"2.61E-02"},{"v":0.010151923,"d":"1.02E-02"},"MAPK1/CREB1/EGFR",3,{"v":6.837158203,"d":"6.84"}]
["GO-BP","GO:0001942","hair follicle development",{"v":0.009510071,"d":"9.51E-03"},{"v":0.026255379,"d":"2.63E-02"},{"v":0.010199062,"d":"1.02E-02"},"SMAD4/EGFR",2,{"v":13.56831395,"d":"13.57"}]
["GO-BP","GO:0007260","tyrosine phosphorylation of STAT protein",{"v":0.009510071,"d":"9.51E-03"},{"v":0.026255379,"d":"2.63E-02"},{"v":0.010199062,"d":"1.02E-02"},"STAT3/JAK2",2,{"v":13.56831395,"d":"13.57"}]
["GO-BP","GO:0042058","regulation of epidermal growth factor receptor signaling pathway",{"v":0.009510071,"d":"9.51E-03"},{"v":0.026255379,"d":"2.63E-02"},{"v":0.010199062,"d":"1.02E-02"},"AKT1/EGFR",2,{"v":13.56831395,"d":"13.57"}]
["GO-BP","GO:0060291","long-term synaptic potentiation",{"v":0.009510071,"d":"9.51E-03"},{"v":0.026255379,"d":"2.63E-02"},{"v":0.010199062,"d":"1.02E-02"},"MAPK1/CREB1",2,{"v":13.56831395,"d":"13.57"}]
["GO-BP","GO:0033673","negative regulation of kinase activity",{"v":0.009524493,"d":"9.52E-03"},{"v":0.026266108,"d":"2.63E-02"},{"v":0.01020323,"d":"1.02E-02"},"PTPN6/HSPB1/AKT1",3,{"v":6.810554475,"d":"6.81"}]
["GO-BP","GO:0014068","positive regulation of phosphatidylinositol 3-kinase signaling",{"v":0.009723493,"d":"9.72E-03"},{"v":0.026785269,"d":"2.68E-02"},{"v":0.010404901,"d":"1.04E-02"},"PTPN6/JAK2",2,{"v":13.41235632,"d":"13.41"}]
["GO-BP","GO:0009791","post-embryonic development",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"ATM/SMAD2",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0022404","molting cycle process",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"SMAD4/EGFR",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0022405","hair cycle process",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"SMAD4/EGFR",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0034103","regulation of tissue remodeling",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"TP53/EGFR",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0097194","execution phase of apoptosis",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"TP53/AKT1",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0098773","skin epidermis development",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"SMAD4/EGFR",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:1900407","regulation of cellular response to oxidative stress",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"HSPB1/AKT1",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:1904035","regulation of epithelial cell apoptotic process",{"v":0.009939048,"d":"9.94E-03"},{"v":0.027139154,"d":"2.71E-02"},{"v":0.01054237,"d":"1.05E-02"},"EIF2S1/JAK2",2,{"v":13.25994318,"d":"13.26"}]
["GO-BP","GO:0007281","germ cell development",{"v":0.010035468,"d":"1.00E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"SMAD5/ATM/AKT1",3,{"v":6.680582061,"d":"6.68"}]
["GO-BP","GO:0046427","positive regulation of receptor signaling pathway via JAK-STAT",{"v":0.010156729,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"STAT3/JAK2",2,{"v":13.11095506,"d":"13.11"}]
["GO-BP","GO:0060021","roof of mouth development",{"v":0.010156729,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"SMAD4/SMAD2",2,{"v":13.11095506,"d":"13.11"}]
["GO-BP","GO:0097306","cellular response to alcohol",{"v":0.010156729,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"PRKAA1/AKT1",2,{"v":13.11095506,"d":"13.11"}]
["GO-BP","GO:0002326","B cell lineage commitment",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"TP53",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0002924","negative regulation of humoral immune response mediated by circulating immunoglobulin",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"PTPN6",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0006113","fermentation",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"TP53",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0007182","common-partner SMAD protein phosphorylation",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"SMAD2",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0032055","negative regulation of translation in response to stress",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"EIF2S1",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0032430","positive regulation of phospholipase A2 activity",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"EGFR",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0043400","cortisol secretion",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"PTPN11",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0043465","regulation of fermentation",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"TP53",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0046880","regulation of follicle-stimulating hormone secretion",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"SMAD4",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0046881","positive regulation of follicle-stimulating hormone secretion",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"SMAD4",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0048289","isotype switching to IgE isotypes",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"STAT6",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0048293","regulation of isotype switching to IgE isotypes",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"STAT6",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0051462","regulation of cortisol secretion",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"PTPN11",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0061419","positive regulation of transcription from RNA polymerase II promoter in response to hypoxia",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"TP53",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0071500","cellular response to nitrosative stress",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"ATM",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0140212","regulation of long-chain fatty acid import into cell",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"AKT1",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:1903626","positive regulation of DNA catabolic process",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"ATM",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:1903719","regulation of I-kappaB phosphorylation",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"AKT1",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:1904415","regulation of xenophagy",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"TBK1",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:1904417","positive regulation of xenophagy",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"TBK1",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:1905323","telomerase holoenzyme complex assembly",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"ATM",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:2000138","positive regulation of cell proliferation involved in heart morphogenesis",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"SMAD4",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:2000489","regulation of hepatic stellate cell activation",{"v":0.010241278,"d":"1.02E-02"},{"v":0.027161177,"d":"2.72E-02"},{"v":0.010550925,"d":"1.06E-02"},"RPS6KA1",1,{"v":97.23958333,"d":"97.24"}]
["GO-BP","GO:0010717","regulation of epithelial to mesenchymal transition",{"v":0.010376528,"d":"1.04E-02"},{"v":0.027403268,"d":"2.74E-02"},{"v":0.010644967,"d":"1.06E-02"},"SMAD4/SMAD2",2,{"v":12.96527778,"d":"12.97"}]
["GO-BP","GO:0014033","neural crest cell differentiation",{"v":0.010376528,"d":"1.04E-02"},{"v":0.027403268,"d":"2.74E-02"},{"v":0.010644967,"d":"1.06E-02"},"SMAD4/MAPK1",2,{"v":12.96527778,"d":"12.97"}]
["GO-BP","GO:0032651","regulation of interleukin-1 beta production",{"v":0.010376528,"d":"1.04E-02"},{"v":0.027403268,"d":"2.74E-02"},{"v":0.010644967,"d":"1.06E-02"},"HSPB1/JAK2",2,{"v":12.96527778,"d":"12.97"}]
["GO-BP","GO:0045185","maintenance of protein location",{"v":0.010376528,"d":"1.04E-02"},{"v":0.027403268,"d":"2.74E-02"},{"v":0.010644967,"d":"1.06E-02"},"NFKBIA/AKT1",2,{"v":12.96527778,"d":"12.97"}]
["GO-BP","GO:0044839","cell cycle G2/M phase transition",{"v":0.010455611,"d":"1.05E-02"},{"v":0.027582897,"d":"2.76E-02"},{"v":0.010714745,"d":"1.07E-02"},"TP53/ATM/PSMD9",3,{"v":6.58012218,"d":"6.58"}]
["GO-BP","GO:1901988","negative regulation of cell cycle phase transition",{"v":0.010562231,"d":"1.06E-02"},{"v":0.027834717,"d":"2.78E-02"},{"v":0.010812566,"d":"1.08E-02"},"TP53/ATM/PSMD9",3,{"v":6.555477528,"d":"6.56"}]
["GO-BP","GO:0030510","regulation of BMP signaling pathway",{"v":0.010598438,"d":"1.06E-02"},{"v":0.02784184,"d":"2.78E-02"},{"v":0.010815333,"d":"1.08E-02"},"SMAD4/SMAD2",2,{"v":12.8228022,"d":"12.82"}]
["GO-BP","GO:0060333","interferon-gamma-mediated signaling pathway",{"v":0.010598438,"d":"1.06E-02"},{"v":0.02784184,"d":"2.78E-02"},{"v":0.010815333,"d":"1.08E-02"},"TP53/JAK2",2,{"v":12.8228022,"d":"12.82"}]
["GO-BP","GO:1901992","positive regulation of mitotic cell cycle phase transition",{"v":0.010598438,"d":"1.06E-02"},{"v":0.02784184,"d":"2.78E-02"},{"v":0.010815333,"d":"1.08E-02"},"AKT1/EGFR",2,{"v":12.8228022,"d":"12.82"}]
["GO-BP","GO:0043491","protein kinase B signaling",{"v":0.010777379,"d":"1.08E-02"},{"v":0.028281312,"d":"2.83E-02"},{"v":0.010986048,"d":"1.10E-02"},"PTPN11/AKT1/EGFR",3,{"v":6.506737918,"d":"6.51"}]
["GO-BP","GO:0035710","CD4-positive, alpha-beta T cell activation",{"v":0.010822451,"d":"1.08E-02"},{"v":0.028281312,"d":"2.83E-02"},{"v":0.010986048,"d":"1.10E-02"},"STAT3/STAT6",2,{"v":12.68342391,"d":"12.68"}]
["GO-BP","GO:0045833","negative regulation of lipid metabolic process",{"v":0.010822451,"d":"1.08E-02"},{"v":0.028281312,"d":"2.83E-02"},{"v":0.010986048,"d":"1.10E-02"},"PRKAA1/AKT1",2,{"v":12.68342391,"d":"12.68"}]
["GO-BP","GO:1904894","positive regulation of receptor signaling pathway via STAT",{"v":0.010822451,"d":"1.08E-02"},{"v":0.028281312,"d":"2.83E-02"},{"v":0.010986048,"d":"1.10E-02"},"STAT3/JAK2",2,{"v":12.68342391,"d":"12.68"}]
["GO-BP","GO:2000117","negative regulation of cysteine-type endopeptidase activity",{"v":0.010822451,"d":"1.08E-02"},{"v":0.028281312,"d":"2.83E-02"},{"v":0.010986048,"d":"1.10E-02"},"RPS6KA1/AKT1",2,{"v":12.68342391,"d":"12.68"}]
["GO-BP","GO:0007589","body fluid secretion",{"v":0.011048561,"d":"1.10E-02"},{"v":0.028781674,"d":"2.88E-02"},{"v":0.011180417,"d":"1.12E-02"},"CREB1/STAT5A",2,{"v":12.54704301,"d":"12.55"}]
["GO-BP","GO:0010972","negative regulation of G2/M transition of mitotic cell cycle",{"v":0.011048561,"d":"1.10E-02"},{"v":0.028781674,"d":"2.88E-02"},{"v":0.011180417,"d":"1.12E-02"},"ATM/PSMD9",2,{"v":12.54704301,"d":"12.55"}]
["GO-BP","GO:1901184","regulation of ERBB signaling pathway",{"v":0.011048561,"d":"1.10E-02"},{"v":0.028781674,"d":"2.88E-02"},{"v":0.011180417,"d":"1.12E-02"},"AKT1/EGFR",2,{"v":12.54704301,"d":"12.55"}]
["GO-BP","GO:1902105","regulation of leukocyte differentiation",{"v":0.011104879,"d":"1.11E-02"},{"v":0.028898187,"d":"2.89E-02"},{"v":0.011225677,"d":"1.12E-02"},"PTPN6/CREB1/ZAP70",3,{"v":6.434972426,"d":"6.43"}]
["GO-BP","GO:0002702","positive regulation of production of molecular mediator of immune response",{"v":0.011507037,"d":"1.15E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"MAPK14/STAT6",2,{"v":12.28289474,"d":"12.28"}]
["GO-BP","GO:0042116","macrophage activation",{"v":0.011507037,"d":"1.15E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"ATM/JAK2",2,{"v":12.28289474,"d":"12.28"}]
["GO-BP","GO:0044070","regulation of anion transport",{"v":0.011507037,"d":"1.15E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"MAP2K6/AKT1",2,{"v":12.28289474,"d":"12.28"}]
["GO-BP","GO:1903076","regulation of protein localization to plasma membrane",{"v":0.011507037,"d":"1.15E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"AKT1/EGFR",2,{"v":12.28289474,"d":"12.28"}]
["GO-BP","GO:0007411","axon guidance",{"v":0.011550495,"d":"1.16E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4/PTPN11/MAPK1",3,{"v":6.341711957,"d":"6.34"}]
["GO-BP","GO:0097485","neuron projection guidance",{"v":0.011663502,"d":"1.17E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4/PTPN11/MAPK1",3,{"v":6.31881769,"d":"6.32"}]
["GO-BP","GO:0008585","female gonad development",{"v":0.01173939,"d":"1.17E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4/ATM",2,{"v":12.15494792,"d":"12.15"}]
["GO-BP","GO:0010660","regulation of muscle cell apoptotic process",{"v":0.01173939,"d":"1.17E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"TP53/JAK2",2,{"v":12.15494792,"d":"12.15"}]
["GO-BP","GO:0030219","megakaryocyte differentiation",{"v":0.01173939,"d":"1.17E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"PTPN6/PTPN11",2,{"v":12.15494792,"d":"12.15"}]
["GO-BP","GO:0032755","positive regulation of interleukin-6 production",{"v":0.01173939,"d":"1.17E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"PTPN11/STAT3",2,{"v":12.15494792,"d":"12.15"}]
["GO-BP","GO:0048010","vascular endothelial growth factor receptor signaling pathway",{"v":0.01173939,"d":"1.17E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"MAPK14/HSPB1",2,{"v":12.15494792,"d":"12.15"}]
["GO-BP","GO:0001822","kidney development",{"v":0.011777151,"d":"1.18E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4/SMAD5/SMAD2",3,{"v":6.296088129,"d":"6.30"}]
["GO-BP","GO:0060485","mesenchyme development",{"v":0.011891443,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4/MAPK1/SMAD2",3,{"v":6.273521505,"d":"6.27"}]
["GO-BP","GO:0003360","brainstem development",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0006924","activation-induced cell death of T cells",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"AKT1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0007253","cytoplasmic sequestering of NF-kappaB",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"NFKBIA",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0015959","diadenosine polyphosphate metabolic process",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"MAPK1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0019530","taurine metabolic process",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"STAT5A",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0019694","alkanesulfonate metabolic process",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"STAT5A",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0032278","positive regulation of gonadotropin secretion",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0032287","peripheral nervous system myelin maintenance",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"AKT1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0033684","regulation of luteinizing hormone secretion",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0035771","interleukin-4-mediated signaling pathway",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"STAT6",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0038026","reelin-mediated signaling pathway",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"STAT5A",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0038089","positive regulation of cell migration by vascular endothelial growth factor signaling pathway",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"HSPB1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0038107","nodal signaling pathway involved in determination of left/right asymmetry",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD2",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0045359","positive regulation of interferon-beta biosynthetic process",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"TBK1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0045362","positive regulation of interleukin-1 biosynthetic process",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"JAK2",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0046884","follicle-stimulating hormone secretion",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD4",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0050725","positive regulation of interleukin-1 beta biosynthetic process",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"JAK2",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0061744","motor behavior",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"PRKAA1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0061762","CAMKK-AMPK signaling cascade",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"PRKAA1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0071494","cellular response to UV-C",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"TP53",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:1900094","regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD2",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:1900107","regulation of nodal signaling pathway",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD2",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:1900164","nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"SMAD2",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:1901525","negative regulation of mitophagy",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"TP53",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:1905097","regulation of guanyl-nucleotide exchange factor activity",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"EIF2S1",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:1990144","intrinsic apoptotic signaling pathway in response to hypoxia",{"v":0.01193825,"d":"1.19E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"TP53",1,{"v":83.34821429,"d":"83.35"}]
["GO-BP","GO:0015908","fatty acid transport",{"v":0.01197381,"d":"1.20E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"MAP2K6/AKT1",2,{"v":12.02963918,"d":"12.03"}]
["GO-BP","GO:0030316","osteoclast differentiation",{"v":0.01197381,"d":"1.20E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"MAPK14/CREB1",2,{"v":12.02963918,"d":"12.03"}]
["GO-BP","GO:0044773","mitotic DNA damage checkpoint",{"v":0.01197381,"d":"1.20E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"TP53/ATM",2,{"v":12.02963918,"d":"12.03"}]
["GO-BP","GO:0120162","positive regulation of cold-induced thermogenesis",{"v":0.01197381,"d":"1.20E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"JAK2/STAT6",2,{"v":12.02963918,"d":"12.03"}]
["GO-BP","GO:1902882","regulation of response to oxidative stress",{"v":0.01197381,"d":"1.20E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"HSPB1/AKT1",2,{"v":12.02963918,"d":"12.03"}]
["GO-BP","GO:2001022","positive regulation of response to DNA damage stimulus",{"v":0.01197381,"d":"1.20E-02"},{"v":0.029761423,"d":"2.98E-02"},{"v":0.011561006,"d":"1.16E-02"},"ATM/EGFR",2,{"v":12.02963918,"d":"12.03"}]
["GO-BP","GO:2001243","negative regulation of intrinsic apoptotic signaling pathway",{"v":0.012210289,"d":"1.22E-02"},{"v":0.030318973,"d":"3.03E-02"},{"v":0.01177759,"d":"1.18E-02"},"HSPB1/AKT1",2,{"v":11.90688776,"d":"11.91"}]
["GO-BP","GO:0044262","cellular carbohydrate metabolic process",{"v":0.012238184,"d":"1.22E-02"},{"v":0.030358002,"d":"3.04E-02"},{"v":0.011792751,"d":"1.18E-02"},"TP53/STAT3/AKT1",3,{"v":6.206781915,"d":"6.21"}]
["GO-BP","GO:0070301","cellular response to hydrogen peroxide",{"v":0.012448819,"d":"1.24E-02"},{"v":0.030849808,"d":"3.08E-02"},{"v":0.011983796,"d":"1.20E-02"},"STAT6/PRKAA1",2,{"v":11.78661616,"d":"11.79"}]
["GO-BP","GO:0031647","regulation of protein stability",{"v":0.012472571,"d":"1.25E-02"},{"v":0.030877974,"d":"3.09E-02"},{"v":0.011994737,"d":"1.20E-02"},"TP53/MAPK1/CREB1",3,{"v":6.163072183,"d":"6.16"}]
["GO-BP","GO:0010657","muscle cell apoptotic process",{"v":0.012689395,"d":"1.27E-02"},{"v":0.031371185,"d":"3.14E-02"},{"v":0.012186328,"d":"1.22E-02"},"TP53/JAK2",2,{"v":11.66875,"d":"11.67"}]
["GO-BP","GO:0002440","production of molecular mediator of immune response",{"v":0.012709546,"d":"1.27E-02"},{"v":0.031371185,"d":"3.14E-02"},{"v":0.012186328,"d":"1.22E-02"},"MAPK14/ATM/STAT6",3,{"v":6.119973776,"d":"6.12"}]
["GO-BP","GO:0060828","regulation of canonical Wnt signaling pathway",{"v":0.012709546,"d":"1.27E-02"},{"v":0.031371185,"d":"3.14E-02"},{"v":0.012186328,"d":"1.22E-02"},"MAPK14/PSMD9/EGFR",3,{"v":6.119973776,"d":"6.12"}]
["GO-BP","GO:0032611","interleukin-1 beta production",{"v":0.012932008,"d":"1.29E-02"},{"v":0.031857209,"d":"3.19E-02"},{"v":0.012375127,"d":"1.24E-02"},"HSPB1/JAK2",2,{"v":11.55321782,"d":"11.55"}]
["GO-BP","GO:0046545","development of primary female sexual characteristics",{"v":0.012932008,"d":"1.29E-02"},{"v":0.031857209,"d":"3.19E-02"},{"v":0.012375127,"d":"1.24E-02"},"SMAD4/ATM",2,{"v":11.55321782,"d":"11.55"}]
["GO-BP","GO:0000079","regulation of cyclin-dependent protein serine/threonine kinase activity",{"v":0.013176651,"d":"1.32E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"AKT1/EGFR",2,{"v":11.43995098,"d":"11.44"}]
["GO-BP","GO:0035335","peptidyl-tyrosine dephosphorylation",{"v":0.013176651,"d":"1.32E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"PTPN6/PTPN11",2,{"v":11.43995098,"d":"11.44"}]
["GO-BP","GO:0032652","regulation of interleukin-1 production",{"v":0.013423317,"d":"1.34E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"HSPB1/JAK2",2,{"v":11.3288835,"d":"11.33"}]
["GO-BP","GO:0006310","DNA recombination",{"v":0.013436038,"d":"1.34E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"RBM14/ATM/STAT6",3,{"v":5.99422089,"d":"5.99"}]
["GO-BP","GO:0090287","regulation of cellular response to growth factor stimulus",{"v":0.013436038,"d":"1.34E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"TP53/SMAD4/SMAD2",3,{"v":5.99422089,"d":"5.99"}]
["GO-BP","GO:0051146","striated muscle cell differentiation",{"v":0.013559397,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"MAPK14/SMAD4/AKT1",3,{"v":5.973762799,"d":"5.97"}]
["GO-BP","GO:0072001","renal system development",{"v":0.013559397,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4/SMAD5/SMAD2",3,{"v":5.973762799,"d":"5.97"}]
["GO-BP","GO:0000733","DNA strand renaturation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"TP53",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0002741","positive regulation of cytokine secretion involved in immune response",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"MAPK14",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0003140","determination of left/right asymmetry in lateral mesoderm",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD2",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0003190","atrioventricular valve formation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0003348","cardiac endothelial cell differentiation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0007406","negative regulation of neuroblast proliferation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"TP53",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0010727","negative regulation of hydrogen peroxide metabolic process",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"STAT3",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0032071","regulation of endodeoxyribonuclease activity",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"AKT1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0032075","positive regulation of nuclease activity",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"AKT1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0032906","transforming growth factor beta2 production",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0032909","regulation of transforming growth factor beta2 production",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0032927","positive regulation of activin receptor signaling pathway",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD2",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0035655","interleukin-18-mediated signaling pathway",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"AKT1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0035733","hepatic stellate cell activation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"RPS6KA1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0036289","peptidyl-serine autophosphorylation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"ATM",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0038114","interleukin-21-mediated signaling pathway",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"STAT3",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0045350","interferon-beta biosynthetic process",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"TBK1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0045357","regulation of interferon-beta biosynthetic process",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"TBK1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0046476","glycosylceramide biosynthetic process",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"PRKAA1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0046600","negative regulation of centriole replication",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"RBM14",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0048539","bone marrow development",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"TP53",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0048733","sebaceous gland development",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0051195","negative regulation of cofactor metabolic process",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"STAT3",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0060430","lung saccule development",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"CREB1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0060956","endocardial cell differentiation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0070459","prolactin secretion",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"EGFR",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0071351","cellular response to interleukin-18",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"AKT1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0090045","positive regulation of deacetylase activity",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"MAPK8",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0098756","response to interleukin-21",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"STAT3",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0098757","cellular response to interleukin-21",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"STAT3",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0099004","calmodulin dependent kinase signaling pathway",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"PRKAA1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:1904354","negative regulation of telomere capping",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"ATM",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:2000192","negative regulation of fatty acid transport",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"AKT1",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:2000617","positive regulation of histone H3-K9 acetylation",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"SMAD4",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:2001182","regulation of interleukin-12 secretion",{"v":0.013632403,"d":"1.36E-02"},{"v":0.032244383,"d":"3.22E-02"},{"v":0.012525527,"d":"1.25E-02"},"MAPK14",1,{"v":72.9296875,"d":"72.93"}]
["GO-BP","GO:0008630","intrinsic apoptotic signaling pathway in response to DNA damage",{"v":0.013671999,"d":"1.37E-02"},{"v":0.032246257,"d":"3.22E-02"},{"v":0.012526255,"d":"1.25E-02"},"TP53/ATM",2,{"v":11.21995192,"d":"11.22"}]
["GO-BP","GO:0071887","leukocyte apoptotic process",{"v":0.013671999,"d":"1.37E-02"},{"v":0.032246257,"d":"3.22E-02"},{"v":0.012526255,"d":"1.25E-02"},"TP53/AKT1",2,{"v":11.21995192,"d":"11.22"}]
["GO-BP","GO:0090100","positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway",{"v":0.013671999,"d":"1.37E-02"},{"v":0.032246257,"d":"3.22E-02"},{"v":0.012526255,"d":"1.25E-02"},"SMAD4/SMAD2",2,{"v":11.21995192,"d":"11.22"}]
["GO-BP","GO:0032006","regulation of TOR signaling",{"v":0.01392269,"d":"1.39E-02"},{"v":0.032708031,"d":"3.27E-02"},{"v":0.012705634,"d":"1.27E-02"},"ATM/PRKAA1",2,{"v":11.11309524,"d":"11.11"}]
["GO-BP","GO:0055017","cardiac muscle tissue growth",{"v":0.01392269,"d":"1.39E-02"},{"v":0.032708031,"d":"3.27E-02"},{"v":0.012705634,"d":"1.27E-02"},"MAPK14/MAPK1",2,{"v":11.11309524,"d":"11.11"}]
["GO-BP","GO:1902750","negative regulation of cell cycle G2/M phase transition",{"v":0.01392269,"d":"1.39E-02"},{"v":0.032708031,"d":"3.27E-02"},{"v":0.012705634,"d":"1.27E-02"},"ATM/PSMD9",2,{"v":11.11309524,"d":"11.11"}]
["GO-BP","GO:0001818","negative regulation of cytokine production",{"v":0.013933385,"d":"1.39E-02"},{"v":0.032708031,"d":"3.27E-02"},{"v":0.012705634,"d":"1.27E-02"},"PTPN6/RPS6KA4/TBK1",3,{"v":5.913217905,"d":"5.91"}]
["GO-BP","GO:0050890","cognition",{"v":0.013933385,"d":"1.39E-02"},{"v":0.032708031,"d":"3.27E-02"},{"v":0.012705634,"d":"1.27E-02"},"MAPK1/CREB1/EGFR",3,{"v":5.913217905,"d":"5.91"}]
["GO-BP","GO:1903522","regulation of blood circulation",{"v":0.014059354,"d":"1.41E-02"},{"v":0.03297269,"d":"3.30E-02"},{"v":0.012808442,"d":"1.28E-02"},"JAK2/AKT1/EGFR",3,{"v":5.893308081,"d":"5.89"}]
["GO-BP","GO:0042136","neurotransmitter biosynthetic process",{"v":0.014175382,"d":"1.42E-02"},{"v":0.033120176,"d":"3.31E-02"},{"v":0.012865734,"d":"1.29E-02"},"JAK2/AKT1",2,{"v":11.00825472,"d":"11.01"}]
["GO-BP","GO:0044774","mitotic DNA integrity checkpoint",{"v":0.014175382,"d":"1.42E-02"},{"v":0.033120176,"d":"3.31E-02"},{"v":0.012865734,"d":"1.29E-02"},"TP53/ATM",2,{"v":11.00825472,"d":"11.01"}]
["GO-BP","GO:1901989","positive regulation of cell cycle phase transition",{"v":0.014175382,"d":"1.42E-02"},{"v":0.033120176,"d":"3.31E-02"},{"v":0.012865734,"d":"1.29E-02"},"AKT1/EGFR",2,{"v":11.00825472,"d":"11.01"}]
["GO-BP","GO:1904029","regulation of cyclin-dependent protein kinase activity",{"v":0.014175382,"d":"1.42E-02"},{"v":0.033120176,"d":"3.31E-02"},{"v":0.012865734,"d":"1.29E-02"},"AKT1/EGFR",2,{"v":11.00825472,"d":"11.01"}]
["GO-BP","GO:0030330","DNA damage response, signal transduction by p53 class mediator",{"v":0.014430069,"d":"1.44E-02"},{"v":0.033652162,"d":"3.37E-02"},{"v":0.013072388,"d":"1.31E-02"},"TP53/ATM",2,{"v":10.90537383,"d":"10.91"}]
["GO-BP","GO:0051341","regulation of oxidoreductase activity",{"v":0.014430069,"d":"1.44E-02"},{"v":0.033652162,"d":"3.37E-02"},{"v":0.013072388,"d":"1.31E-02"},"AKT1/EGFR",2,{"v":10.90537383,"d":"10.91"}]
["GO-BP","GO:0006275","regulation of DNA replication",{"v":0.014686743,"d":"1.47E-02"},{"v":0.034154897,"d":"3.42E-02"},{"v":0.013267678,"d":"1.33E-02"},"TP53/EGFR",2,{"v":10.80439815,"d":"10.80"}]
["GO-BP","GO:0032526","response to retinoic acid",{"v":0.014686743,"d":"1.47E-02"},{"v":0.034154897,"d":"3.42E-02"},{"v":0.013267678,"d":"1.33E-02"},"ATM/CREB1",2,{"v":10.80439815,"d":"10.80"}]
["GO-BP","GO:0071156","regulation of cell cycle arrest",{"v":0.014686743,"d":"1.47E-02"},{"v":0.034154897,"d":"3.42E-02"},{"v":0.013267678,"d":"1.33E-02"},"TP53/ATM",2,{"v":10.80439815,"d":"10.80"}]
["GO-BP","GO:0046034","ATP metabolic process",{"v":0.01495947,"d":"1.50E-02"},{"v":0.034756719,"d":"3.48E-02"},{"v":0.013501459,"d":"1.35E-02"},"TP53/STAT3/PRKAA1",3,{"v":5.757606908,"d":"5.76"}]
["GO-BP","GO:0002327","immature B cell differentiation",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"ATM",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0006678","glucosylceramide metabolic process",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"PRKAA1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0010728","regulation of hydrogen peroxide biosynthetic process",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"STAT3",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0031053","primary miRNA processing",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"SMAD2",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0042473","outer ear morphogenesis",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"MAPK1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0045542","positive regulation of cholesterol biosynthetic process",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"PRKAA1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0048617","embryonic foregut morphogenesis",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"SMAD2",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0060502","epithelial cell proliferation involved in lung morphogenesis",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"MAP2K1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0070417","cellular response to cold",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"NFKBIA",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0090043","regulation of tubulin deacetylation",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"PRKAA1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0098792","xenophagy",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"TBK1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0099641","anterograde axonal protein transport",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"HSPB1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0106120","positive regulation of sterol biosynthetic process",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"PRKAA1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:1903147","negative regulation of autophagy of mitochondrion",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"TP53",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:1904685","positive regulation of metalloendopeptidase activity",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"STAT3",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:1990314","cellular response to insulin-like growth factor stimulus",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"CREB1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:2000382","positive regulation of mesoderm development",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"SMAD2",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:2000674","regulation of type B pancreatic cell apoptotic process",{"v":0.015323741,"d":"1.53E-02"},{"v":0.035015662,"d":"3.50E-02"},{"v":0.013602047,"d":"1.36E-02"},"EIF2S1",1,{"v":64.82638889,"d":"64.83"}]
["GO-BP","GO:0072676","lymphocyte migration",{"v":0.015468616,"d":"1.55E-02"},{"v":0.035282031,"d":"3.53E-02"},{"v":0.01370552,"d":"1.37E-02"},"ZAP70/AKT1",2,{"v":10.51238739,"d":"10.51"}]
["GO-BP","GO:1904019","epithelial cell apoptotic process",{"v":0.015468616,"d":"1.55E-02"},{"v":0.035282031,"d":"3.53E-02"},{"v":0.01370552,"d":"1.37E-02"},"EIF2S1/JAK2",2,{"v":10.51238739,"d":"10.51"}]
["GO-BP","GO:0003279","cardiac septum development",{"v":0.015733168,"d":"1.57E-02"},{"v":0.035722029,"d":"3.57E-02"},{"v":0.01387644,"d":"1.39E-02"},"TP53/SMAD4",2,{"v":10.41852679,"d":"10.42"}]
["GO-BP","GO:0010906","regulation of glucose metabolic process",{"v":0.015733168,"d":"1.57E-02"},{"v":0.035722029,"d":"3.57E-02"},{"v":0.01387644,"d":"1.39E-02"},"TP53/AKT1",2,{"v":10.41852679,"d":"10.42"}]
["GO-BP","GO:0042303","molting cycle",{"v":0.015733168,"d":"1.57E-02"},{"v":0.035722029,"d":"3.57E-02"},{"v":0.01387644,"d":"1.39E-02"},"SMAD4/EGFR",2,{"v":10.41852679,"d":"10.42"}]
["GO-BP","GO:0042633","hair cycle",{"v":0.015733168,"d":"1.57E-02"},{"v":0.035722029,"d":"3.57E-02"},{"v":0.01387644,"d":"1.39E-02"},"SMAD4/EGFR",2,{"v":10.41852679,"d":"10.42"}]
["GO-BP","GO:0060419","heart growth",{"v":0.015733168,"d":"1.57E-02"},{"v":0.035722029,"d":"3.57E-02"},{"v":0.01387644,"d":"1.39E-02"},"MAPK14/MAPK1",2,{"v":10.41852679,"d":"10.42"}]
["GO-BP","GO:0006096","glycolytic process",{"v":0.015999671,"d":"1.60E-02"},{"v":0.036261074,"d":"3.63E-02"},{"v":0.014085835,"d":"1.41E-02"},"STAT3/PRKAA1",2,{"v":10.32632743,"d":"10.33"}]
["GO-BP","GO:0043200","response to amino acid",{"v":0.015999671,"d":"1.60E-02"},{"v":0.036261074,"d":"3.63E-02"},{"v":0.014085835,"d":"1.41E-02"},"CREB1/EGFR",2,{"v":10.32632743,"d":"10.33"}]
["GO-BP","GO:0006757","ATP generation from ADP",{"v":0.01626812,"d":"1.63E-02"},{"v":0.036802561,"d":"3.68E-02"},{"v":0.014296179,"d":"1.43E-02"},"STAT3/PRKAA1",2,{"v":10.23574561,"d":"10.24"}]
["GO-BP","GO:0008543","fibroblast growth factor receptor signaling pathway",{"v":0.01626812,"d":"1.63E-02"},{"v":0.036802561,"d":"3.68E-02"},{"v":0.014296179,"d":"1.43E-02"},"PTPN11/MAPK1",2,{"v":10.23574561,"d":"10.24"}]
["GO-BP","GO:0051235","maintenance of location",{"v":0.016439043,"d":"1.64E-02"},{"v":0.037155515,"d":"3.72E-02"},{"v":0.014433286,"d":"1.44E-02"},"PTPN6/NFKBIA/AKT1",3,{"v":5.556547619,"d":"5.56"}]
["GO-BP","GO:0032612","interleukin-1 production",{"v":0.016538506,"d":"1.65E-02"},{"v":0.037245253,"d":"3.72E-02"},{"v":0.014468146,"d":"1.45E-02"},"HSPB1/JAK2",2,{"v":10.14673913,"d":"10.15"}]
["GO-BP","GO:0046660","female sex differentiation",{"v":0.016538506,"d":"1.65E-02"},{"v":0.037245253,"d":"3.72E-02"},{"v":0.014468146,"d":"1.45E-02"},"SMAD4/ATM",2,{"v":10.14673913,"d":"10.15"}]
["GO-BP","GO:1900542","regulation of purine nucleotide metabolic process",{"v":0.016538506,"d":"1.65E-02"},{"v":0.037245253,"d":"3.72E-02"},{"v":0.014468146,"d":"1.45E-02"},"STAT3/PRKAA1",2,{"v":10.14673913,"d":"10.15"}]
["GO-BP","GO:1904375","regulation of protein localization to cell periphery",{"v":0.016538506,"d":"1.65E-02"},{"v":0.037245253,"d":"3.72E-02"},{"v":0.014468146,"d":"1.45E-02"},"AKT1/EGFR",2,{"v":10.14673913,"d":"10.15"}]
["GO-BP","GO:0021782","glial cell development",{"v":0.016810823,"d":"1.68E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"AKT1/EGFR",2,{"v":10.05926724,"d":"10.06"}]
["GO-BP","GO:2000736","regulation of stem cell differentiation",{"v":0.016810823,"d":"1.68E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"STAT3/PSMD9",2,{"v":10.05926724,"d":"10.06"}]
["GO-BP","GO:0002713","negative regulation of B cell mediated immunity",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"PTPN6",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0002890","negative regulation of immunoglobulin mediated immune response",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"PTPN6",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0007440","foregut morphogenesis",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"SMAD2",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0010749","regulation of nitric oxide mediated signal transduction",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"EGFR",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0010918","positive regulation of mitochondrial membrane potential",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"AKT1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0010944","negative regulation of transcription by competitive promoter binding",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"CREB1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0032070","regulation of deoxyribonuclease activity",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"AKT1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0032275","luteinizing hormone secretion",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"SMAD4",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0032308","positive regulation of prostaglandin secretion",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"MAP2K6",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0032525","somite rostral/caudal axis specification",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"SMAD4",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0033210","leptin-mediated signaling pathway",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"STAT3",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0045348","positive regulation of MHC class II biosynthetic process",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"JAK2",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0045792","negative regulation of cell size",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"AKT1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0046322","negative regulation of fatty acid oxidation",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"AKT1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0048340","paraxial mesoderm morphogenesis",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"SMAD2",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0048382","mesendoderm development",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"SMAD4",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0051409","response to nitrosative stress",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"ATM",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0060033","anatomical structure regression",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"SMAD5",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0070391","response to lipoteichoic acid",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"MAPK14",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0071223","cellular response to lipoteichoic acid",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"MAPK14",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0072610","interleukin-12 secretion",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"MAPK14",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0090205","positive regulation of cholesterol metabolic process",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"PRKAA1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0090336","positive regulation of brown fat cell differentiation",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"MAPK14",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0097050","type B pancreatic cell apoptotic process",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"EIF2S1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0140052","cellular response to oxidised low-density lipoprotein particle stimulus",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"AKT1",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:1903799","negative regulation of production of miRNAs involved in gene silencing by miRNA",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"TP53",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:2000849","regulation of glucocorticoid secretion",{"v":0.01701227,"d":"1.70E-02"},{"v":0.037334146,"d":"3.73E-02"},{"v":0.014502677,"d":"1.45E-02"},"PTPN11",1,{"v":58.34375,"d":"58.34"}]
["GO-BP","GO:0006140","regulation of nucleotide metabolic process",{"v":0.017085064,"d":"1.71E-02"},{"v":0.037395139,"d":"3.74E-02"},{"v":0.01452637,"d":"1.45E-02"},"STAT3/PRKAA1",2,{"v":9.973290598,"d":"9.97"}]
["GO-BP","GO:0051153","regulation of striated muscle cell differentiation",{"v":0.017085064,"d":"1.71E-02"},{"v":0.037395139,"d":"3.74E-02"},{"v":0.01452637,"d":"1.45E-02"},"MAPK14/SMAD4",2,{"v":9.973290598,"d":"9.97"}]
["GO-BP","GO:1901222","regulation of NIK/NF-kappaB signaling",{"v":0.017085064,"d":"1.71E-02"},{"v":0.037395139,"d":"3.74E-02"},{"v":0.01452637,"d":"1.45E-02"},"NFKBIA/EGFR",2,{"v":9.973290598,"d":"9.97"}]
["GO-BP","GO:0006470","protein dephosphorylation",{"v":0.017279782,"d":"1.73E-02"},{"v":0.037788156,"d":"3.78E-02"},{"v":0.014679039,"d":"1.47E-02"},"PTPN6/PTPN11/JAK2",3,{"v":5.452686916,"d":"5.45"}]
["GO-BP","GO:0009615","response to virus",{"v":0.017565333,"d":"1.76E-02"},{"v":0.038378944,"d":"3.84E-02"},{"v":0.014908535,"d":"1.49E-02"},"MAPK14/HSPB1/TBK1",3,{"v":5.418924149,"d":"5.42"}]
["GO-BP","GO:0010508","positive regulation of autophagy",{"v":0.01791926,"d":"1.79E-02"},{"v":0.039117963,"d":"3.91E-02"},{"v":0.015195611,"d":"1.52E-02"},"TBK1/PRKAA1",2,{"v":9.723958333,"d":"9.72"}]
["GO-BP","GO:0043618","regulation of transcription from RNA polymerase II promoter in response to stress",{"v":0.018201126,"d":"1.82E-02"},{"v":0.03969852,"d":"3.97E-02"},{"v":0.015421132,"d":"1.54E-02"},"TP53/PSMD9",2,{"v":9.643595041,"d":"9.64"}]
["GO-BP","GO:0016999","antibiotic metabolic process",{"v":0.018484882,"d":"1.85E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"STAT3/EGFR",2,{"v":9.56454918,"d":"9.56"}]
["GO-BP","GO:0046031","ADP metabolic process",{"v":0.018484882,"d":"1.85E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"STAT3/PRKAA1",2,{"v":9.56454918,"d":"9.56"}]
["GO-BP","GO:0001655","urogenital system development",{"v":0.018585691,"d":"1.86E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"SMAD4/SMAD5/SMAD2",3,{"v":5.303977273,"d":"5.30"}]
["GO-BP","GO:0002923","regulation of humoral immune response mediated by circulating immunoglobulin",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"PTPN6",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0009950","dorsal/ventral axis specification",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"SMAD2",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0032276","regulation of gonadotropin secretion",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"SMAD4",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0032306","regulation of prostaglandin secretion",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"MAP2K6",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0033629","negative regulation of cell adhesion mediated by integrin",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"PTPN11",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0035933","glucocorticoid secretion",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"PTPN11",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0045060","negative thymic T cell selection",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"ZAP70",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0045141","meiotic telomere clustering",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"ATM",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0045351","type I interferon biosynthetic process",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"TBK1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0051974","negative regulation of telomerase activity",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"TP53",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0061307","cardiac neural crest cell differentiation involved in heart development",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"MAPK1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0061308","cardiac neural crest cell development involved in heart development",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"MAPK1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0070673","response to interleukin-18",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"AKT1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0072537","fibroblast activation",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"RPS6KA1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0072584","caveolin-mediated endocytosis",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"MAPK1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0090042","tubulin deacetylation",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"PRKAA1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:1902065","response to L-glutamate",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"CREB1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:1905383","protein localization to presynapse",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"HSPB1",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:1990440","positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"TP53",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:2000615","regulation of histone H3-K9 acetylation",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"SMAD4",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:2001269","positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway",{"v":0.018697994,"d":"1.87E-02"},{"v":0.03994353,"d":"3.99E-02"},{"v":0.015516308,"d":"1.55E-02"},"JAK2",1,{"v":53.03977273,"d":"53.04"}]
["GO-BP","GO:0051053","negative regulation of DNA metabolic process",{"v":0.018770521,"d":"1.88E-02"},{"v":0.040064133,"d":"4.01E-02"},{"v":0.015563157,"d":"1.56E-02"},"TP53/ATM",2,{"v":9.486788618,"d":"9.49"}]
["GO-BP","GO:0090150","establishment of protein localization to membrane",{"v":0.018883211,"d":"1.89E-02"},{"v":0.040270185,"d":"4.03E-02"},{"v":0.015643199,"d":"1.56E-02"},"MAPK8/TP53/EGFR",3,{"v":5.272025602,"d":"5.27"}]
["GO-BP","GO:0060070","canonical Wnt signaling pathway",{"v":0.01933449,"d":"1.93E-02"},{"v":0.041189676,"d":"4.12E-02"},{"v":0.016000381,"d":"1.60E-02"},"MAPK14/PSMD9/EGFR",3,{"v":5.224813433,"d":"5.22"}]
["GO-BP","GO:2000134","negative regulation of G1/S transition of mitotic cell cycle",{"v":0.019347417,"d":"1.93E-02"},{"v":0.041189676,"d":"4.12E-02"},{"v":0.016000381,"d":"1.60E-02"},"TP53/ATM",2,{"v":9.335,"d":"9.34"}]
["GO-BP","GO:0090101","negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway",{"v":0.019638661,"d":"1.96E-02"},{"v":0.041774046,"d":"4.18E-02"},{"v":0.016227383,"d":"1.62E-02"},"TP53/SMAD2",2,{"v":9.260912698,"d":"9.26"}]
["GO-BP","GO:0002921","negative regulation of humoral immune response",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"PTPN6",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0006983","ER overload response",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"TP53",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0010826","negative regulation of centrosome duplication",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"RBM14",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0010960","magnesium ion homeostasis",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"EGFR",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0032042","mitochondrial DNA metabolic process",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"TP53",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0032429","regulation of phospholipase A2 activity",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"EGFR",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0038110","interleukin-2-mediated signaling pathway",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"STAT5A",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0042118","endothelial cell activation",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"SMAD4",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0043383","negative T cell selection",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"ZAP70",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0051095","regulation of helicase activity",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"TP53",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0060019","radial glial cell differentiation",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"STAT3",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0060391","positive regulation of SMAD protein signal transduction",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"SMAD4",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0070243","regulation of thymocyte apoptotic process",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"TP53",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0070486","leukocyte aggregation",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"ZAP70",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0071044","histone mRNA catabolic process",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"ATM",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0071481","cellular response to X-ray",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"ATM",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0072520","seminiferous tubule development",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"SMAD4",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0072540","T-helper 17 cell lineage commitment",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"STAT3",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0090220","chromosome localization to nuclear envelope involved in homologous chromosome segregation",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"ATM",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0150065","regulation of deacetylase activity",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"MAPK8",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:1904424","regulation of GTP binding",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"EIF2S1",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:2001223","negative regulation of neuron migration",{"v":0.020380918,"d":"2.04E-02"},{"v":0.042554127,"d":"4.26E-02"},{"v":0.01653041,"d":"1.65E-02"},"STAT3",1,{"v":48.61979167,"d":"48.62"}]
["GO-BP","GO:0003206","cardiac chamber morphogenesis",{"v":0.020523497,"d":"2.05E-02"},{"v":0.042708746,"d":"4.27E-02"},{"v":0.016590473,"d":"1.66E-02"},"TP53/SMAD4",2,{"v":9.045542636,"d":"9.05"}]
["GO-BP","GO:0050853","B cell receptor signaling pathway",{"v":0.020523497,"d":"2.05E-02"},{"v":0.042708746,"d":"4.27E-02"},{"v":0.016590473,"d":"1.66E-02"},"PTPN6/MAPK1",2,{"v":9.045542636,"d":"9.05"}]
["GO-BP","GO:0071482","cellular response to light stimulus",{"v":0.020523497,"d":"2.05E-02"},{"v":0.042708746,"d":"4.27E-02"},{"v":0.016590473,"d":"1.66E-02"},"TP53/EIF2S1",2,{"v":9.045542636,"d":"9.05"}]
["GO-BP","GO:1903038","negative regulation of leukocyte cell-cell adhesion",{"v":0.020523497,"d":"2.05E-02"},{"v":0.042708746,"d":"4.27E-02"},{"v":0.016590473,"d":"1.66E-02"},"PTPN6/AKT1",2,{"v":9.045542636,"d":"9.05"}]
["GO-BP","GO:0010721","negative regulation of cell development",{"v":0.020724368,"d":"2.07E-02"},{"v":0.043090784,"d":"4.31E-02"},{"v":0.016738878,"d":"1.67E-02"},"TP53/SMAD4/STAT3",3,{"v":5.088117733,"d":"5.09"}]
["GO-BP","GO:0030518","intracellular steroid hormone receptor signaling pathway",{"v":0.02082212,"d":"2.08E-02"},{"v":0.043257955,"d":"4.33E-02"},{"v":0.016803816,"d":"1.68E-02"},"RBM14/JAK2",2,{"v":8.975961538,"d":"8.98"}]
["GO-BP","GO:1902807","negative regulation of cell cycle G1/S phase transition",{"v":0.021122572,"d":"2.11E-02"},{"v":0.043845605,"d":"4.38E-02"},{"v":0.017032093,"d":"1.70E-02"},"TP53/ATM",2,{"v":8.907442748,"d":"8.91"}]
["GO-BP","GO:0006165","nucleoside diphosphate phosphorylation",{"v":0.021424845,"d":"2.14E-02"},{"v":0.044436055,"d":"4.44E-02"},{"v":0.017261457,"d":"1.73E-02"},"STAT3/PRKAA1",2,{"v":8.839962121,"d":"8.84"}]
["GO-BP","GO:0009135","purine nucleoside diphosphate metabolic process",{"v":0.022034827,"d":"2.20E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT3/PRKAA1",2,{"v":8.708022388,"d":"8.71"}]
["GO-BP","GO:0009179","purine ribonucleoside diphosphate metabolic process",{"v":0.022034827,"d":"2.20E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT3/PRKAA1",2,{"v":8.708022388,"d":"8.71"}]
["GO-BP","GO:0032355","response to estradiol",{"v":0.022034827,"d":"2.20E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT3/EGFR",2,{"v":8.708022388,"d":"8.71"}]
["GO-BP","GO:0046939","nucleotide phosphorylation",{"v":0.022034827,"d":"2.20E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT3/PRKAA1",2,{"v":8.708022388,"d":"8.71"}]
["GO-BP","GO:0048565","digestive tract development",{"v":0.022034827,"d":"2.20E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"SMAD2/EGFR",2,{"v":8.708022388,"d":"8.71"}]
["GO-BP","GO:0002829","negative regulation of type 2 immune response",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT6",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0003157","endocardium development",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"SMAD4",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0007494","midgut development",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"EGFR",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0010745","negative regulation of macrophage derived foam cell differentiation",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"NFKBIA",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0010763","positive regulation of fibroblast migration",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"AKT1",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0010870","positive regulation of receptor biosynthetic process",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"JAK2",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0034397","telomere localization",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"ATM",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0043248","proteasome assembly",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"PSMD9",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0043970","histone H3-K9 acetylation",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"SMAD4",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0045059","positive thymic T cell selection",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"ZAP70",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0045820","negative regulation of glycolytic process",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT3",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0050722","regulation of interleukin-1 beta biosynthetic process",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"JAK2",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0060123","regulation of growth hormone secretion",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"PTPN11",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0060340","positive regulation of type I interferon-mediated signaling pathway",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"TBK1",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0060712","spongiotrophoblast layer development",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"AKT1",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0061029","eyelid development in camera-type eye",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"EGFR",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0070431","nucleotide-binding oligomerization domain containing 2 signaling pathway",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"NFKBIA",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0071287","cellular response to manganese ion",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"EIF2S1",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0071352","cellular response to interleukin-2",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT5A",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0099640","axo-dendritic protein transport",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"HSPB1",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:1903960","negative regulation of anion transmembrane transport",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"AKT1",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:2001171","positive regulation of ATP biosynthetic process",{"v":0.022061045,"d":"2.21E-02"},{"v":0.044750353,"d":"4.48E-02"},{"v":0.017383548,"d":"1.74E-02"},"STAT3",1,{"v":44.87980769,"d":"44.88"}]
["GO-BP","GO:0001889","liver development",{"v":0.022342524,"d":"2.23E-02"},{"v":0.045247694,"d":"4.52E-02"},{"v":0.017576743,"d":"1.76E-02"},"RPS6KA1/EGFR",2,{"v":8.643518519,"d":"8.64"}]
["GO-BP","GO:0050921","positive regulation of chemotaxis",{"v":0.022342524,"d":"2.23E-02"},{"v":0.045247694,"d":"4.52E-02"},{"v":0.017576743,"d":"1.76E-02"},"MAPK14/HSPB1",2,{"v":8.643518519,"d":"8.64"}]
["GO-BP","GO:0009185","ribonucleoside diphosphate metabolic process",{"v":0.022652015,"d":"2.27E-02"},{"v":0.045837234,"d":"4.58E-02"},{"v":0.017805753,"d":"1.78E-02"},"STAT3/PRKAA1",2,{"v":8.579963235,"d":"8.58"}]
["GO-BP","GO:0046425","regulation of receptor signaling pathway via JAK-STAT",{"v":0.022963293,"d":"2.30E-02"},{"v":0.046429432,"d":"4.64E-02"},{"v":0.018035796,"d":"1.80E-02"},"STAT3/JAK2",2,{"v":8.517335766,"d":"8.52"}]
["GO-BP","GO:0045861","negative regulation of proteolysis",{"v":0.022994084,"d":"2.30E-02"},{"v":0.046454012,"d":"4.65E-02"},{"v":0.018045344,"d":"1.80E-02"},"TP53/RPS6KA1/AKT1",3,{"v":4.889141061,"d":"4.89"}]
["GO-BP","GO:0061008","hepaticobiliary system development",{"v":0.023276353,"d":"2.33E-02"},{"v":0.046986193,"d":"4.70E-02"},{"v":0.018252073,"d":"1.83E-02"},"RPS6KA1/EGFR",2,{"v":8.455615942,"d":"8.46"}]
["GO-BP","GO:0002460","adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",{"v":0.023497532,"d":"2.35E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"PTPN6/STAT3/STAT6",3,{"v":4.84851108,"d":"4.85"}]
["GO-BP","GO:0022412","cellular process involved in reproduction in multicellular organism",{"v":0.023497532,"d":"2.35E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"SMAD5/ATM/AKT1",3,{"v":4.84851108,"d":"4.85"}]
["GO-BP","GO:0002700","regulation of production of molecular mediator of immune response",{"v":0.023591188,"d":"2.36E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"MAPK14/STAT6",2,{"v":8.394784173,"d":"8.39"}]
["GO-BP","GO:0003188","heart valve formation",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"SMAD4",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0003214","cardiac left ventricle morphogenesis",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"SMAD4",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0032310","prostaglandin secretion",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"MAP2K6",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0036092","phosphatidylinositol-3-phosphate biosynthetic process",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"ATM",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0043558","regulation of translational initiation in response to stress",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"EIF2S1",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0045346","regulation of MHC class II biosynthetic process",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"JAK2",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0046606","negative regulation of centrosome cycle",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"RBM14",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0050720","interleukin-1 beta biosynthetic process",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"JAK2",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0070234","positive regulation of T cell apoptotic process",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"TP53",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0070669","response to interleukin-2",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"STAT5A",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0071361","cellular response to ethanol",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"PRKAA1",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0072425","signal transduction involved in G2 DNA damage checkpoint",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"ATM",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:1903624","regulation of DNA catabolic process",{"v":0.02373838,"d":"2.37E-02"},{"v":0.04730598,"d":"4.73E-02"},{"v":0.018376297,"d":"1.84E-02"},"ATM",1,{"v":41.67410714,"d":"41.67"}]
["GO-BP","GO:0006936","muscle contraction",{"v":0.023836516,"d":"2.38E-02"},{"v":0.047425725,"d":"4.74E-02"},{"v":0.018422812,"d":"1.84E-02"},"MAP2K3/SMAD5/MAP2K6",3,{"v":4.821797521,"d":"4.82"}]
["GO-BP","GO:0030111","regulation of Wnt signaling pathway",{"v":0.023836516,"d":"2.38E-02"},{"v":0.047425725,"d":"4.74E-02"},{"v":0.018422812,"d":"1.84E-02"},"MAPK14/PSMD9/EGFR",3,{"v":4.821797521,"d":"4.82"}]
["GO-BP","GO:0001837","epithelial to mesenchymal transition",{"v":0.024226154,"d":"2.42E-02"},{"v":0.048124146,"d":"4.81E-02"},{"v":0.018694118,"d":"1.87E-02"},"SMAD4/SMAD2",2,{"v":8.27570922,"d":"8.28"}]
["GO-BP","GO:0050709","negative regulation of protein secretion",{"v":0.024226154,"d":"2.42E-02"},{"v":0.048124146,"d":"4.81E-02"},{"v":0.018694118,"d":"1.87E-02"},"PTPN11/PSMD9",2,{"v":8.27570922,"d":"8.28"}]
["GO-BP","GO:0002218","activation of innate immune response",{"v":0.024546273,"d":"2.45E-02"},{"v":0.048682466,"d":"4.87E-02"},{"v":0.018911001,"d":"1.89E-02"},"RBM14/PSMD9",2,{"v":8.217429577,"d":"8.22"}]
["GO-BP","GO:0007030","Golgi organization",{"v":0.024546273,"d":"2.45E-02"},{"v":0.048682466,"d":"4.87E-02"},{"v":0.018911001,"d":"1.89E-02"},"MAP2K1/MAPK1",2,{"v":8.217429577,"d":"8.22"}]
["GO-BP","GO:0035296","regulation of tube diameter",{"v":0.024868141,"d":"2.49E-02"},{"v":0.049203393,"d":"4.92E-02"},{"v":0.019113358,"d":"1.91E-02"},"AKT1/EGFR",2,{"v":8.159965035,"d":"8.16"}]
["GO-BP","GO:0044344","cellular response to fibroblast growth factor stimulus",{"v":0.024868141,"d":"2.49E-02"},{"v":0.049203393,"d":"4.92E-02"},{"v":0.019113358,"d":"1.91E-02"},"PTPN11/MAPK1",2,{"v":8.159965035,"d":"8.16"}]
["GO-BP","GO:0097746","regulation of blood vessel diameter",{"v":0.024868141,"d":"2.49E-02"},{"v":0.049203393,"d":"4.92E-02"},{"v":0.019113358,"d":"1.91E-02"},"AKT1/EGFR",2,{"v":8.159965035,"d":"8.16"}]
["GO-BP","GO:0035150","regulation of tube size",{"v":0.02519175,"d":"2.52E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"AKT1/EGFR",2,{"v":8.103298611,"d":"8.10"}]
["GO-BP","GO:0071322","cellular response to carbohydrate stimulus",{"v":0.02519175,"d":"2.52E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"MAP2K6/PRKAA1",2,{"v":8.103298611,"d":"8.10"}]
["GO-BP","GO:1902107","positive regulation of leukocyte differentiation",{"v":0.02519175,"d":"2.52E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"CREB1/ZAP70",2,{"v":8.103298611,"d":"8.10"}]
["GO-BP","GO:0006390","mitochondrial transcription",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"PRKAA1",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0010759","positive regulation of macrophage chemotaxis",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"MAPK14",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0032274","gonadotropin secretion",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"SMAD4",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0033151","V(D)J recombination",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"ATM",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0034349","glial cell apoptotic process",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"TP53",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0042159","lipoprotein catabolic process",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"ATM",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0042921","glucocorticoid receptor signaling pathway",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"RBM14",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0042976","activation of Janus kinase activity",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"JAK2",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0043517","positive regulation of DNA damage response, signal transduction by p53 class mediator",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"ATM",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0044539","long-chain fatty acid import into cell",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"AKT1",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0045342","MHC class II biosynthetic process",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"JAK2",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0045360","regulation of interleukin-1 biosynthetic process",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"JAK2",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0045410","positive regulation of interleukin-6 biosynthetic process",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"STAT3",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0045838","positive regulation of membrane potential",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"AKT1",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0048368","lateral mesoderm development",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"SMAD2",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0055089","fatty acid homeostasis",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"PRKAA1",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0072075","metanephric mesenchyme development",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"SMAD4",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0140354","lipid import into cell",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"AKT1",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:1900119","positive regulation of execution phase of apoptosis",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"TP53",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:2000402","negative regulation of lymphocyte migration",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"AKT1",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:2001028","positive regulation of endothelial cell chemotaxis",{"v":0.025412928,"d":"2.54E-02"},{"v":0.049341456,"d":"4.93E-02"},{"v":0.01916699,"d":"1.92E-02"},"HSPB1",1,{"v":38.89583333,"d":"38.90"}]
["GO-BP","GO:0002822","regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",{"v":0.025517094,"d":"2.55E-02"},{"v":0.049505148,"d":"4.95E-02"},{"v":0.019230577,"d":"1.92E-02"},"PTPN6/STAT6",2,{"v":8.047413793,"d":"8.05"}]
["GO-BP","GO:0002224","toll-like receptor signaling pathway",{"v":0.025844167,"d":"2.58E-02"},{"v":0.049906669,"d":"4.99E-02"},{"v":0.01938655,"d":"1.94E-02"},"TBK1/NFKBIA",2,{"v":7.992294521,"d":"7.99"}]
["GO-BP","GO:0042542","response to hydrogen peroxide",{"v":0.025844167,"d":"2.58E-02"},{"v":0.049906669,"d":"4.99E-02"},{"v":0.01938655,"d":"1.94E-02"},"STAT6/PRKAA1",2,{"v":7.992294521,"d":"7.99"}]
["GO-BP","GO:0051250","negative regulation of lymphocyte activation",{"v":0.025844167,"d":"2.58E-02"},{"v":0.049906669,"d":"4.99E-02"},{"v":0.01938655,"d":"1.94E-02"},"PTPN6/ATM",2,{"v":7.992294521,"d":"7.99"}]
["GO-BP","GO:0051384","response to glucocorticoid",{"v":0.025844167,"d":"2.58E-02"},{"v":0.049906669,"d":"4.99E-02"},{"v":0.01938655,"d":"1.94E-02"},"EIF4EBP1/EGFR",2,{"v":7.992294521,"d":"7.99"}]
["GO-BP","GO:0055123","digestive system development",{"v":0.025844167,"d":"2.58E-02"},{"v":0.049906669,"d":"4.99E-02"},{"v":0.01938655,"d":"1.94E-02"},"SMAD2/EGFR",2,{"v":7.992294521,"d":"7.99"}]
["GO-BP","GO:1904892","regulation of receptor signaling pathway via STAT",{"v":0.025844167,"d":"2.58E-02"},{"v":0.049906669,"d":"4.99E-02"},{"v":0.01938655,"d":"1.94E-02"},"STAT3/JAK2",2,{"v":7.992294521,"d":"7.99"}]