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["Additional file 8. The enriched Gene ontology (GO) terms of down-regulated genes in oral cancer"]
[]
[null,"ID","Description"," Benjamini corrected P-value"]
["Biological Processes (BP)","GO:0003002","regionalization",1.24e-27]
[null,"GO:0009952","anterior/posterior pattern formation",1.11e-26]
[null,"GO:0007389","pattern specification process",1.81e-24]
[null,"GO:0001501","skeletal system development",1.14e-20]
[null,"GO:0048598","embryonic morphogenesis",7.56e-19]
[null,"GO:0009954","proximal/distal pattern formation",3.54e-15]
[null,"GO:0030326","embryonic limb morphogenesis",3.54e-15]
[null,"GO:0035113","embryonic appendage morphogenesis",3.54e-15]
[null,"GO:0035107","appendage morphogenesis",8.38e-15]
[null,"GO:0035108","limb morphogenesis",8.38e-15]
[null,"GO:0048736","appendage development",8.38e-15]
[null,"GO:0060173","limb development",8.38e-15]
[null,"GO:0051252","regulation of RNA metabolic process",2.49e-12]
[null,"GO:0006355","regulation of transcription, DNA-dependent",1.47e-11]
[null,"GO:0048705","skeletal system morphogenesis",9.27e-11]
[null,"GO:0048706","embryonic skeletal system development",1.18e-10]
[null,"GO:0001655","urogenital system development",4.31e-09]
[null,"GO:0045449","regulation of transcription",1.09e-08]
[null,"GO:0043009","chordate embryonic development",4.04e-08]
[null,"GO:0035295","tube development",{"v":1.38e-07,"d":"1.38E-07"}]
[null,"GO:0009792","embryonic development ending in birth or egg hatching",{"v":1.64e-07,"d":"1.64E-07"}]
[null,"GO:0042733","embryonic digit morphogenesis",{"v":2.05e-07,"d":"2.05E-07"}]
[null,"GO:0048732","gland development",{"v":2.8e-07,"d":"2.80E-07"}]
[null,"GO:0009953","dorsal/ventral pattern formation",{"v":4.12e-07,"d":"4.12E-07"}]
[null,"GO:0048562","embryonic organ morphogenesis",{"v":5.49e-07,"d":"5.49E-07"}]
[null,"GO:0035239","tube morphogenesis",{"v":1.82e-06,"d":"1.82E-06"}]
[null,"GO:0048568","embryonic organ development",{"v":2.1e-06,"d":"2.10E-06"}]
[null,"GO:0048729","tissue morphogenesis",{"v":2.63e-06,"d":"2.63E-06"}]
[null,"GO:0002009","morphogenesis of an epithelium",{"v":2.84e-06,"d":"2.84E-06"}]
[null,"GO:0048704","embryonic skeletal system morphogenesis",{"v":5.57e-06,"d":"5.57E-06"}]
[null,"GO:0007398","ectoderm development",{"v":1.98e-05,"d":"1.98E-05"}]
[null,"GO:0007267","cell-cell signaling",{"v":4.26e-05,"d":"4.26E-05"}]
[null,"GO:0045944","positive regulation of transcription from RNA polymerase II promoter",{"v":5.1e-05,"d":"5.10E-05"}]
[null,"GO:0007423","sensory organ development",{"v":6.8e-05,"d":"6.80E-05"}]
[null,"GO:0046546","development of primary male sexual characteristics",{"v":7.92e-05,"d":"7.92E-05"}]
[null,"GO:0048592","eye morphogenesis",{"v":7.92e-05,"d":"7.92E-05"}]
[null,"GO:0006357","regulation of transcription from RNA polymerase II promoter",{"v":0.000111,"d":"1.11E-04"}]
[null,"GO:0048608","reproductive structure development",{"v":0.000135,"d":"1.35E-04"}]
[null,"GO:0045893","positive regulation of transcription, DNA-dependent",{"v":0.000179,"d":"1.79E-04"}]
[null,"GO:0060429","epithelium development",{"v":0.000179,"d":"1.79E-04"}]
[null,"GO:0051254","positive regulation of RNA metabolic process",{"v":0.000185,"d":"1.85E-04"}]
[null,"GO:0008544","epidermis development",{"v":0.000247,"d":"2.47E-04"}]
[null,"GO:0021680","cerebellar Purkinje cell layer development",{"v":0.000248,"d":"2.48E-04"}]
[null,"GO:0045941","positive regulation of transcription",{"v":0.000386,"d":"3.86E-04"}]
[null,"GO:0021517","ventral spinal cord development",{"v":0.000386,"d":"3.86E-04"}]
[null,"GO:0021522","spinal cord motor neuron differentiation",{"v":0.000386,"d":"3.86E-04"}]
[null,"GO:0010628","positive regulation of gene expression",{"v":0.000411,"d":"4.11E-04"}]
[null,"GO:0046661","male sex differentiation",{"v":0.00051,"d":"5.10E-04"}]
[null,"GO:0021575","hindbrain morphogenesis",{"v":0.000531,"d":"5.31E-04"}]
[null,"GO:0030539","male genitalia development",{"v":0.000531,"d":"5.31E-04"}]
[null,"GO:0045935","positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process",{"v":0.000597,"d":"5.97E-04"}]
[null,"GO:0008284","positive regulation of cell proliferation",{"v":0.00061,"d":"6.10E-04"}]
[null,"GO:0003006","reproductive developmental process",{"v":0.000651,"d":"6.51E-04"}]
[null,"GO:0048806","genitalia development",{"v":0.000682,"d":"6.82E-04"}]
[null,"GO:0051173","positive regulation of nitrogen compound metabolic process",{"v":0.000682,"d":"6.82E-04"}]
[null,"GO:0010557","positive regulation of macromolecule biosynthetic process",{"v":0.000767,"d":"7.67E-04"}]
[null,"GO:0022037","metencephalon development",{"v":0.000863,"d":"8.63E-04"}]
[null,"GO:0031328","positive regulation of cellular biosynthetic process",{"v":0.00089,"d":"8.90E-04"}]
[null,"GO:0009891","positive regulation of biosynthetic process",{"v":0.000973,"d":"9.73E-04"}]
[null,"GO:0048663","neuron fate commitment",{"v":0.00105,"d":"1.05E-03"}]
[null,"GO:0045137","development of primary sexual characteristics",{"v":0.00164,"d":"1.64E-03"}]
[null,"GO:0030097","hemopoiesis",{"v":0.00174,"d":"1.74E-03"}]
[null,"GO:0001841","neural tube formation",{"v":0.00174,"d":"1.74E-03"}]
[null,"GO:0001843","neural tube closure",{"v":0.00174,"d":"1.74E-03"}]
[null,"GO:0014020","primary neural tube formation",{"v":0.00174,"d":"1.74E-03"}]
[null,"GO:0060606","tube closure",{"v":0.00174,"d":"1.74E-03"}]
[null,"GO:0042127","regulation of cell proliferation",{"v":0.00186,"d":"1.86E-03"}]
[null,"GO:0001838","embryonic epithelial tube formation",{"v":0.0019,"d":"1.90E-03"}]
[null,"GO:0030902","hindbrain development",{"v":0.0019,"d":"1.90E-03"}]
[null,"GO:0035148","tube lumen formation",{"v":0.0019,"d":"1.90E-03"}]
[null,"GO:0007548","sex differentiation",{"v":0.0019,"d":"1.90E-03"}]
[null,"GO:0010604","positive regulation of macromolecule metabolic process",{"v":0.0019,"d":"1.90E-03"}]
[null,"GO:0060562","epithelial tube morphogenesis",{"v":0.00215,"d":"2.15E-03"}]
[null,"GO:0021915","neural tube development",{"v":0.00241,"d":"2.41E-03"}]
[null,"GO:0048839","inner ear development",{"v":0.00241,"d":"2.41E-03"}]
[null,"GO:0016331","morphogenesis of embryonic epithelium",{"v":0.00271,"d":"2.71E-03"}]
[null,"GO:0030099","myeloid cell differentiation",{"v":0.00339,"d":"3.39E-03"}]
[null,"GO:0030182","neuron differentiation",{"v":0.00479,"d":"4.79E-03"}]
[null,"GO:0045597","positive regulation of cell differentiation",{"v":0.00609,"d":"6.09E-03"}]
[null,"GO:0048666","neuron development",{"v":0.00723,"d":"7.23E-03"}]
[null,"GO:0046545","development of primary female sexual characteristics",{"v":0.00809,"d":"8.09E-03"}]
[null,"GO:0046660","female sex differentiation",{"v":0.00809,"d":"8.09E-03"}]
[null,"GO:0048534","hemopoietic or lymphoid organ development",{"v":0.00809,"d":"8.09E-03"}]
[null,"GO:0002520","immune system development",{"v":0.00929,"d":"9.29E-03"}]
["Cellular Components (CC)","GO:0005576","extracellular region",{"v":6.19e-05,"d":"6.19E-05"}]
[null,"GO:0044421","extracellular region part",{"v":0.000261,"d":"2.61E-04"}]
[null,"GO:0005615","extracellular space",{"v":0.000514,"d":"5.14E-04"}]
[null,"GO:0005578","proteinaceous extracellular matrix",{"v":0.00966,"d":"9.66E-03"}]
[null,"GO:0005581","collagen",{"v":0.00966,"d":"9.66E-03"}]
["Molecular Function (MF)","GO:0043565","sequence-specific DNA binding",6.68e-24]
[null,"GO:0003700","transcription factor activity",1.32e-16]
[null,"GO:0030528","transcription regulator activity",3.36e-12]
[null,"GO:0003677","DNA binding",7.59e-10]
[null,"GO:0003702","RNA polymerase II transcription factor activity",{"v":0.000886,"d":"8.86E-04"}]
[null,"GO:0008514","organic anion transmembrane transporter activity",{"v":0.000966,"d":"9.66E-04"}]
[null,"GO:0015125","bile acid transmembrane transporter activity",{"v":0.000966,"d":"9.66E-04"}]
[null,"GO:0016564","transcription repressor activity",{"v":0.00279,"d":"2.79E-03"}]
[null,"GO:0008028","monocarboxylic acid transmembrane transporter activity",{"v":0.00423,"d":"4.23E-03"}]
["Note: Benjamini corrected P-value: Benjamini and Hochberg False Discovery Rate (FDR) correction."]

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["Cellular Components (CC)","GO:0005576","extracellular region",{"v":2.26e-05,"d":"2.26E-05"}]
[null,"GO:0044421","extracellular region part",{"v":0.00436,"d":"4.36E-03"}]
[null,"GO:0005923","tight junction",{"v":0.00436,"d":"4.36E-03"}]
[null,"GO:0070160","occluding junction",{"v":0.00436,"d":"4.36E-03"}]
[null,"GO:0043296","apical junction complex",{"v":0.00436,"d":"4.36E-03"}]
[null,"GO:0016327","apicolateral plasma membrane",{"v":0.00985,"d":"9.85E-03"}]
["molecular function (MF)","GO:0005372","water transporter activity ",{"v":0.00176,"d":"1.76E-03"}]
[null,"GO:0015250","water channel activity",{"v":0.00176,"d":"1.76E-03"}]
[null,"GO:0042802","identical protein binding",{"v":0.00715,"d":"7.15E-03"}]
[null,"GO:0015168","glycerol transmembrane transporter activity",{"v":0.00896,"d":"8.96E-03"}]
[null,"GO:0015254","glycerol channel activity",{"v":0.00896,"d":"8.96E-03"}]
[null,"GO:0031705","bombesin receptor binding",{"v":0.00896,"d":"8.96E-03"}]
[null,"GO:0031708","endothelin B receptor binding",{"v":0.00896,"d":"8.96E-03"}]
[null,"GO:0047961","glycine N-acyltransferase activity",{"v":0.00896,"d":"8.96E-03"}]
[null,"GO:0050508","glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity",{"v":0.00896,"d":"8.96E-03"}]
["Note: Benjamini corrected P-value: Benjamini and Hochberg False Discovery Rate (FDR) correction."]